Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Exposure to asbestos in the use of consumer spackling, patching, and taping compounds. | Analysis of representative samples of spackling, patching, and jointing compounds, purchased at retail stores in the New York City area, has shown that some contain asbestos minerals as well as other biologically active substances. Measurements suggest that home repair work involving the use of such materials may resul... | ['Asbestos', 'Construction Materials', 'Environmental Exposure', 'Humans'] | 1,145,211 | [['D01.578.725.050', 'D01.837.725.700.760.070'], ['J01.637.241'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Schwannoma of the breast showing massive exophytic growth: a case report. | Schwannoma is a slow-growing tumor that frequently occurs in the extremities, the trunk and the head region. Its occurrence in the breast is rare with only a few cases being reported. We present here the case of breast schwannoma in a 41-year-old woman who presented with a palpable mass in her right breast. This is the... | ['Adult', 'Breast Neoplasms', 'Female', 'Humans', 'Immunohistochemistry', 'Magnetic Resonance Imaging', 'Neurilemmoma', 'S100 Proteins', 'Ultrasonography, Mammary'] | 16,844,378 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Prosthetic rehabilitation of a midfacial defect resulting from lethal midline granuloma--a clinical report. | Prosthetic rehabilitation of the midfacial defects has always perplexed maxillofacial prosthodontists. These midfacial defects lead to functional and cosmetic deficiencies. One of the causes of such defects is midline lethal granuloma, which is a destructive granulomatous lesion of uncertain aetiology, involving the no... | ['Adult', 'Granuloma, Lethal Midline', 'Humans', 'Male', 'Maxillofacial Prosthesis', 'Mouth Diseases', 'Nose Deformities, Acquired', 'Palate', 'Paranasal Sinus Diseases', 'Treatment Outcome'] | 17,002,746 | [['M01.060.116'], ['C08.460.393', 'C09.603.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.510'], ['C07.465'], ['C08.460.619', 'C09.603.619'], ['A14.521.658', 'A14.549.617'], ['C08.460.692', 'C09.603.692'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The reach of commercially motivated junk news on Facebook. | Commercially motivated junk news-i.e. money-driven, highly shareable clickbait with low journalistic production standards-constitutes a vast and largely unexplored news media ecosystem. Using publicly available Facebook data, we compared the reach of junk news on Facebook pages in the Netherlands to the reach of Dutch ... | ['Commerce', 'Humans', 'Journalism', 'Mass Media', 'Netherlands', 'Social Media'] | 31,369,596 | [['J01.219'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.737.498'], ['L01.178.590'], ['Z01.542.651'], ['L01.178.751', 'L01.224.230.110.500.750']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
[Delays in the diagnosis of lung cancer]. | OBJECTIVE: To study the clinical and demographic factors associated with delays in the diagnosis of lung cancer.PATIENTS AND METHODS: A 2-year prospective study of patients admitted to the respiratory medicine ward with a suspected diagnosis of lung cancer. We studied demographic factors, health care received, place of... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Length of Stay', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Office Visits', 'Patient Admission', 'Prospective Studies', 'Spain', 'Time Factors'] | 14,533,992 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['N04.452.758.635'], ['E02.760.400.600', 'N02.421.585.400.600'], ['E05.318.372.500.750.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Integrating Geriatrics Into Oncology Ambulatory Care Clinics | BACKGROUND: Geriatric oncology offers specialized care that incorporates comprehensive geriatric assessment (CGA) and multidisciplinary teams (MDTs) with oncology care. Geriatric syndromes, comorbidities, and caregiver concerns are relevant to the oncology assessment in older adult patients to make treatment decisions,... | ['Aged', 'Ambulatory Care Facilities', 'Geriatrics', 'Humans', 'Neoplasms', 'Patient Care Team'] | 26,207,721 | [['M01.060.116.100'], ['N02.278.035'], ['H02.403.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['N04.590.715']] | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Anterior spinal artery aneurysm. Case report. | An anomaly of the anterior spinal artery in association with a berry aneurysm is reported. The embryological basis for this previously unreported combination is reviewed. | ['Adult', 'Arteries', 'Basilar Artery', 'Female', 'Humans', 'Intracranial Aneurysm', 'Rupture, Spontaneous', 'Spinal Cord'] | 7,420,184 | [['M01.060.116'], ['A07.015.114'], ['A07.015.114.106'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['C23.300.909'], ['A08.186.854']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incidence of cancer in a cohort of magnesium production workers. | The results from a cohort study on the incidence of cancer and the mortality in a cohort of 2391 male workers producing magnesium metal are presented. The study population was restricted to employees with more than one year of work experience in the study plant between 1951 and 1974 and the cohort was observed from 195... | ['Chemical Industry', 'Cohort Studies', 'Humans', 'Incidence', 'Lip Neoplasms', 'Lung Neoplasms', 'Magnesium', 'Male', 'Neoplasms', 'Norway', 'Occupational Diseases', 'Stomach Neoplasms'] | 2,789,964 | [['J01.576.655.437'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04.588.443.591.550', 'C07.465.409.640', 'C07.465.530.... | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: a mechanistic study with 12 months follow-up. | OBJECTIVE: To perform a mechanistic study on the effect of interleukin (IL)-1 blockade by anakinra in patients with refractory myositis and to explore possible predictive biomarkers.METHODS: Fifteen patients with refractory myositis were treated with anakinra for 12 months. Clinical response was assessed by the six-ite... | ['Aged', 'Antirheumatic Agents', 'Biomarkers', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Flow Cytometry', 'Follow-Up Studies', 'Humans', 'Immunohistochemistry', 'Interleukin 1 Receptor Antagonist Protein', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Myositis', 'T-Lymphocyte Subsets', 'T-Lymphocytes', 'Treatment O... | 23,625,983 | [['M01.060.116.100'], ['D27.505.954.329'], ['D23.101'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.34... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells. | We previously isolated and characterized a Chinese hamster ovary (CHO) cell mutant, ZPG207, that is defective in import of proteins carrying a peroxisome-targeting signal type 2 (PTS2) nonapeptide. Herein we have cloned Chinese hamster (Cl) PEX7 encoding the PTS2 receptor. ClPex7p consists of 318 amino acids, shorter t... | ['Amino Acid Sequence', 'Animals', 'Antibody Specificity', 'Base Sequence', 'Biological Transport', 'Cell Line', 'Cricetinae', 'Cricetulus', 'Microbodies', 'Molecular Sequence Data', 'Mutation', 'Peroxisomal Targeting Signal 2 Receptor', 'Peroxisome-Targeting Signal 1 Receptor', 'RNA, Messenger', 'Receptors, Cytoplasmi... | 11,756,410 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G12.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G03.143'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['A11.284.430.214.190.500.585', 'A11.284.430.214.190.875.190.190.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Interindividual differences in the capability to change automatized movement patterns. | When modifying established, automatized skills, performers often experience proactive interference resulting in initial performance decrements. Notably, individuals seem to differ quite largely with respect to their interference susceptibility. The aim of the present study was to scrutinize the roots of these interindi... | ['Adult', 'Executive Function', 'Female', 'Fingers', 'Humans', 'Individuality', 'Inhibition, Psychological', 'Male', 'Motor Skills', 'Proactive Inhibition', 'Young Adult'] | 32,050,121 | [['M01.060.116'], ['F02.463.217'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F02.808.260'], ['F01.145.544.538', 'F02.463.425.475.538'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in myometrial expression of progesterone receptor membrane components 1 and 2 are associated with human parturition at term. | While the exact mechanism of human parturition remains unknown, functional progesterone withdrawal is believed to play a key regulatory role. Progesterone receptor membrane components 1 and 2 (PGRMC1, PGRMC2) are putative progesterone receptors and the aim of this project was to investigate their expression in human my... | ['Adult', 'Cells, Cultured', 'Female', 'Gene Expression Regulation', 'Humans', 'Membrane Proteins', 'Myometrium', 'Parturition', 'Pregnancy', 'Protein Transport', 'RNA Interference', 'RNA, Messenger', 'Receptors, Progesterone', 'Signal Transduction', 'Term Birth', 'Transfection'] | 25,266,650 | [['M01.060.116'], ['A11.251'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['A02.633.570.500', 'A05.360.319.679.690', 'A10.690.467.500'], ['G08.686.784.769.490'], ['G08.686.784.769'], ['G03.143.700'], ['G05.308.203.374.790'], ['D13.444.735.544'], ['D12.776.826.750.765'], ['G02.111.820... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of aminoacid decarboxylases by non-steroidal antiinflammatory drugs. | Several non-steroidal antiinflammatory drugs (NSAID) were shown to inhibit to various extents the decarboxylases of ornithine, lysine, histidine, arginine, and tyrosine. The most sensitive enzyme was ornithine decarboxylase, for which piroxicam, benoxaprofen and aminophenazone showed an IC50 of 0.007 mM; ibuprofen comp... | ['Animals', 'Anti-Inflammatory Agents', 'Arginine', 'Aromatic Amino Acid Decarboxylase Inhibitors', 'Carboxy-Lyases', 'Kinetics', 'Lysine', 'Ornithine Decarboxylase Inhibitors', 'Rats', 'Tyrosine'] | 6,442,285 | [['B01.050'], ['D27.505.954.158'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D27.505.519.389.124', 'D27.505.954.427.090.050.249'], ['D08.811.520.224.125'], ['G01.374.661', 'G02.111.490'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['D27.505.519.389.705'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases. | DNA glycosylases are important repair enzymes that eliminate a diverse array of aberrant nucleobases from the genomes of all organisms. Individual bacterial species often contain multiple paralogs of a particular glycosylase, yet the molecular and functional distinctions between these paralogs are not well understood. ... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'DNA', 'DNA Damage', 'DNA Glycosylases', 'DNA Mutational Analysis', 'DNA Repair', 'Models, Molecular', 'Phylogeny', 'Protein Structure, Tertiary', 'Streptococcus mutans'] | 25,978,435 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D13.444.308'], ['G05.200'], ['D08.811.074.249', 'D08.811.277.450.430.099'], ['E05.393.760.700.300'], ['G02.111.222', 'G05.219'], ['E05.599.595'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.570.820.70... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Anti-inflammatory effects of antimicrobial agents: an in vivo study. | Antimicrobials are used emperically in a variety of inflammatory dermatoses such as rosacea and dermatitis herpetiformis, although these diseases are not believed to be of bacterial etiology. We have used potassium iodide ointment to induce follicular pustules and have found in this in vivo model properties of antimicr... | ['Administration, Oral', 'Administration, Topical', 'Anti-Infective Agents', 'Anti-Inflammatory Agents', 'Dermatitis', 'Humans', 'Male', 'Potassium Iodide'] | 1,194,716 | [['E02.319.267.100'], ['E02.319.267.120'], ['D27.505.954.122'], ['D27.505.954.158'], ['C17.800.174'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.475.410.700', 'D01.745.680']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum contains a potent factor that decreases beta-adrenergic receptor-stimulated L-type Ca2+ current in cardiac myocytes. | L-type Ca2+ current (ICa) was measured in cultured atrial myocytes from hearts of adult guinea-pigs using whole-cell voltage clamp. Potentiation of ICa induced by beta-adrenergic stimulation (isoprenaline 2.10(-7) M) could be completely antagonized by diluted sera (1:100 v/v). Half-maximal inhibition of beta-receptor-s... | ['Acetylcholine', 'Adenylate Cyclase Toxin', 'Animals', 'Atrial Function', 'Atropine', 'Blood', 'Calcium Channels', 'Cells, Cultured', 'Cyclic AMP', 'Electric Conductivity', 'Guinea Pigs', 'Heart', 'Isoproterenol', 'Pertussis Toxin', 'Receptors, Adrenergic, beta', 'Virulence Factors, Bordetella'] | 8,391,681 | [['D02.092.211.111'], ['D08.811.520.650.200.040', 'D23.946.123.946.040', 'D23.946.896.980.040'], ['B01.050'], ['G09.330.040'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['A12.207.152', 'A15.145'], ['D12.776.157.530.400.150', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antidepressant activity of aqueous extracts of Curcuma longa in mice. | Curcuma longa (turmeric) is a well-known indigenous herbal medicine. The aqueous extracts, when administered orally to the mice from 140 to 560 mg/kg for 14 days, were able to elicit dose-dependent relation of immobility reduction in the tail suspension test and the forced swimming test in mice. The effects of the extr... | ['Administration, Oral', 'Animals', 'Antidepressive Agents', 'Brain', 'Curcuma', 'Depression', 'Dose-Response Relationship, Drug', 'Fluoxetine', 'Male', 'Mice', 'Mice, Inbred ICR', 'Mitochondria', 'Monoamine Oxidase', 'Motor Activity', 'Phytotherapy', 'Plant Extracts'] | 12,413,724 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.427.700.122'], ['A08.186.211'], ['B01.650.940.800.575.912.250.618.937.900.166'], ['F01.145.126.350'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.092.831.280'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.63... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-performance liquid chromatographic determination of the stereoselective biotransformation of the chiral drug praziquantel. | A selective reversed-phase high-performance liquid chromatographic method for the simultaneous quantification of praziquantel and its monohydroxylated metabolites in serum is described. The quantitative analysis was followed by determination of the enantiomeric ratio of praziquantel and trans-4-hydroxypraziquantel, the... | ['Biotransformation', 'Chromatography, High Pressure Liquid', 'Humans', 'Microsomes, Liver', 'Praziquantel', 'Reference Values', 'Reproducibility of Results', 'Spectrophotometry, Ultraviolet', 'Stereoisomerism'] | 1,400,806 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.835.540.541'], ['D03.633.100.531.690'], ['E05.978.810'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.196.712.726.802', 'E05.196.867.826.802'], [... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The clip-wrap technique in the treatment of intracranial unclippable aneurysms. | UNLABELLED: Fusiform and dolichoectatic aneurysms are challenging lesions to treat with direct clipping. Treatment of these aneurysms often requires alternative surgical strategies, including extracranial-intracranial bypass, wrapping, or clip-wrap techniques. Nonetheless, these alternatives methods of treatment have b... | ['Adult', 'Aged', 'Aneurysm, Ruptured', 'Female', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Neurosurgical Procedures', 'Retrospective Studies', 'Treatment Outcome'] | 20,339,665 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.055.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['M01.060.116.630'], ['E04.525'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Accumulated occurrence of illnesses with Salmonella enteritidis in hospitals and nursing homes in the district Oberallgaeu, Bavaria, in July 2004]. | We report on the investigation of a Salmonella enteritidis outbreak in hospitals and nursing homes in the district Oberallgaeu, Bavaria, in July 2004. Affected by this outbreak were hospital patients, inhabitants of nursing homes, kitchen coworkers and maintenance personnel. Within this outbreak six deaths were observe... | ['Adult', 'Disease Outbreaks', 'Disease Transmission, Infectious', 'Female', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Nursing Homes', 'Prevalence', 'Risk Assessment', 'Risk Factors', 'Salmonella Food Poisoning', 'Salmonella Infections', 'Salmonella enteritidis'] | 16,379,046 | [['M01.060.116'], ['N06.850.290'], ['N06.850.335'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N02.278.825.610'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.740.600.800.715',... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Triple Stimulation Technique in Amyotrophic Lateral Sclerosis. | PURPOSE: To identify upper motor neuron (UMN) dysfunction using the triple stimulation technique (TST) in amyotrophic lateral sclerosis (ALS).METHODS: Fifty ALS and 42 non-ALS patients were examined clinically, using conventional transcranial magnetic stimulation and TST.RESULTS: For ALS patients presenting with UMN in... | ['Adolescent', 'Adult', 'Aged', 'Amyotrophic Lateral Sclerosis', 'Child', 'Electric Stimulation', 'Electrodiagnosis', 'Evoked Potentials, Motor', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motor Neurons', 'Neural Conduction', 'Prospective Studies', 'Transcranial Magnetic Stimulation', 'Upper Extremity', 'Young Adult'] | 30,531,427 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['M01.060.406'], ['E05.723.402'], ['E01.370.405'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mesoangioblasts, vessel-associated multipotent stem cells, repair the infarcted heart by multiple cellular mechanisms: a comparison with bone marrow progenitors, fibroblasts, and endothelial cells. | OBJECTIVE: To test the potential of mesoangioblasts (Mabs) in reducing postischemic injury in comparison with bone marrow progenitor cells (BMPCs), fibroblasts (Fbs), and embryonic stem cell-derived endothelial cells (ECs), and to identify putative cellular protective mechanisms.METHODS AND RESULTS: Cells were injected... | ['Animals', 'Apoptosis', 'Blood Vessels', 'Echocardiography', 'Endothelium, Vascular', 'Fibroblasts', 'Graft Survival', 'Hematopoietic Stem Cells', 'Mesoderm', 'Mice', 'Mice, Inbred C57BL', 'Multipotent Stem Cells', 'Myocardial Infarction', 'Myocardium', 'Neovascularization, Physiologic', 'Stem Cell Transplantation', '... | 15,662,021 | [['B01.050'], ['G04.146.954.035'], ['A07.015'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.015.700.500', 'A10.272.491.355'], ['A11.329.228'], ['G12.875.545.340'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['A16.504.660'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Purification and characterization of a human bradykinin binding protein from inflammatory cells. | Bradykinin (BK) is a potent mediator with a broad spectrum of pharmacological and inflammatory actions which are exerted through cell surface receptors. We report here the affinity chromatographic purification of a novel 14 kDa BK binding protein from human blood neutrophils and also peripheral blood mononuclear cells ... | ['Bradykinin', 'Carrier Proteins', 'Cell Line', 'Cell Membrane', 'Chromatography, Affinity', 'Cross-Linking Reagents', 'Humans', 'Inflammation', 'Inflammation Mediators', 'Leukocytes, Mononuclear', 'Membrane Proteins', 'Molecular Weight', 'Neutrophils', 'Radioligand Assay', 'Receptors, Bradykinin'] | 9,611,777 | [['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['D12.776.157'], ['A11.251.210'], ['A11.284.149'], ['E05.196.181.400.170'], ['D27.720.470.410.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], [... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Health reform in Ecuador: never again the right to health as a privilege]. | The process of the health reform being experienced by Ecuador has had significant achievements because it occurs within the framework of a new Constitution of the Republic, which allowed the incorporation of historical social demands that arose from the criticism of neoliberalism in the restructure and modernization of... | ['Ecuador', 'Health Care Reform', 'Human Rights', 'Humans', 'Public Policy'] | 25,597,730 | [['Z01.107.757.362'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Lateral interactions in the perception of flicker and in the physiology of the lateral geniculate nucleus. | The perception of flicker strength in a center stimulus can be affected by the presence of a surrounding stimulus. We correlated this effect with the interactions between centers and surrounds of the receptive fields (RFs) of neurons in the retino-geniculate pathways. The responses of cells in the lateral geniculate nu... | ['Animals', 'Aotidae', 'Callithrix', 'Contrast Sensitivity', 'Electrophysiology', 'Geniculate Bodies', 'Humans', 'Neurons', 'Photic Stimulation', 'Psychophysics', 'Retina', 'Visual Pathways', 'Visual Perception'] | 15,330,708 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.037'], ['B01.050.150.900.649.313.988.400.600.150.150.114'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['H01.158.344.528', 'H01.158.782.236'], ['A08.186.211.200.317.826.701.444'], ['B01.050.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis. | Hepcidin, a key regulator of iron metabolism, decreases intestinal absorption of iron and its release from macrophages. Iron, anemia, hypoxia, and inflammation were reported to influence hepcidin expression. To investigate regulation of the expression of hepcidin and other iron-related genes, we manipulated erythropoie... | ['Anemia, Hemolytic', 'Animals', 'Antimicrobial Cationic Peptides', 'Cation Transport Proteins', 'Erythropoiesis', 'Erythropoietin', 'Ferritins', 'GPI-Linked Proteins', 'Gamma Rays', 'Gene Expression Regulation', 'Hemochromatosis Protein', 'Hemolysis', 'Hepcidins', 'Iron Compounds', 'Liver', 'Male', 'Membrane Proteins'... | 16,497,104 | [['C15.378.071.141'], ['B01.050'], ['D12.644.050', 'D12.776.543.695.054'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['G04.152.825.414', 'G09.188.343.414'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['D12.776.157.427.249', 'D12.776.55... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical and pathologic features of canine ocular melanomas. | Ocular melanomas in 40 dogs were reviewed and classified by site of origin and cytologic features. An apparent correlation existed between site, cytologic classification, and prognosis. Limbal melanomas and intraocular melanomas classified as spindle A or spindle B were less aggressive and had a more favorable prognosi... | ['Animals', 'Dog Diseases', 'Dogs', 'Eye', 'Eye Neoplasms', 'Female', 'Male', 'Melanoma', 'Uveal Neoplasms'] | 6,698,840 | [['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['A01.456.505.420', 'A09.371'], ['C04.588.364', 'C11.319'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['C04.588.364.978', 'C11.319.494', 'C11.941.855']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The cardiovascular risk profile in persons with normal glucose tolerance with reference to the familial occurrence of diabetes mellitus]. | Of 96 persons each with normal glucose tolerance test (oral glucose tolerance test in all deviations "securely normal"), but different hereditary load with diabetes the cardiovascular risk factors overweight, hypertension, hypertriglyceridaemia, hypercholesterolaemia and hyperuricaemia were established and compared acc... | ['Adolescent', 'Adult', 'Aged', 'Cardiovascular Diseases', 'Diabetes Mellitus', 'Female', 'Glucose Tolerance Test', 'Humans', 'Hypercholesterolemia', 'Hypertension', 'Male', 'Middle Aged', 'Obesity', 'Risk', 'Triglycerides', 'Uric Acid'] | 7,306,279 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14'], ['C18.452.394.750', 'C19.246'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['C14.907.489'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PF-3758309, p21-activated kinase 4 inhibitor, suppresses migration and invasion of A549 human lung cancer cells via regulation of CREB, NF-êB, and â-catenin signalings. | Migration and invasion comprise key steps in cancer metastasis. Through the migration and invasion into and out of lymphatic and/or blood vessels, cancer cells can be spread out into the tissues in remote site from the origin. Degradation of extracellular matrix (ECM) must be preceded prior to the metastasis of cancer ... | ['Cell Line, Tumor', 'Cell Movement', 'Cyclic AMP Response Element-Binding Protein', 'Down-Regulation', 'Extracellular Matrix', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 9', 'NF-kappa B', 'Neoplasm Invasiveness', 'Pyrazoles', 'Pyrroles'... | 24,366,569 | [['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A11.284.295.310'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['D08.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A randomized trial of computer-delivered brief intervention and low-intensity contingency management for smoking during pregnancy. | INTRODUCTION: Implementation of evidence-based interventions for smoking during pregnancy is challenging. We developed 2 highly replicable interventions for smoking during pregnancy: (a) a computer-delivered 5As-based brief intervention (CD-5As) and (b) a computer-assisted, simplified, and low-intensity contingency man... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Motivation', 'Odds Ratio', 'Patient Compliance', 'Patient Education as Topic', 'Pregnancy', 'Prenatal Care', 'Smoking Cessation', 'Smoking Prevention'] | 22,157,229 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.830.600.600'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['I02.233.332.500', 'N0... | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Spectral analysis of fluctuations in heart rate: an objective evaluation of autonomic nervous control in chronic renal failure. | A quantitative, noninvasive method of assessing autonomic control, based on the spectral analysis of beat-to-beat fluctuations in heart rate (HR), was applied to patients with chronic renal failure (RF). Since the power spectrum of HR fluctuations measures the dynamic nervous control of HR, it can be used to quantitate... | ['Adult', 'Aged', 'Aged, 80 and over', 'Autonomic Nervous System', 'Female', 'Heart Rate', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Parasympathetic Nervous System', 'Spectrum Analysis', 'Sympathetic Nervous System'] | 3,574,569 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.800.050'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['A08.800.050.600'], ['E05.196.867'], ['A08.800.050.800']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Experimental study of anti-atherosclerosis potency by lycium seed oil and its possible mechanism]. | OBJECTIVE: To study the effect of anti-atherosclerosis of Lycium Seed Oil (Lso) and its possible mechanism.METHODS: The rabbit atherosclerosis model was established by high fat diet, and the TC, TG, LDL-C, HDL-C levels in plasma were examined dynamically. The SOD, GSH-PX, T-AOC activities and the MDA levels in serum we... | ['Animals', 'Antioxidants', 'Aorta', 'Arteriosclerosis', 'Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Glutathione Peroxidase', 'Hypolipidemic Agents', 'Immunohistochemistry', 'Lipid Peroxidation', 'Lipids', 'Lycium', 'Male', 'Malondialdehyde', 'NF-kappa B', 'Plant Oils', 'Rabbits', 'Reverse Transcr... | 17,918,438 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A07.015.114.056'], ['C14.907.137.126'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.24... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Quality characteristics of cold-dried beef slices. | In this study, salted and pasteurized beef slices were dried to approximately 40% water content at different low temperatures (10, 15 and 20 °C) and air flow rates (1, 2, 3 and 4 m/s) and the quality characteristics of the cold-dried beef slices were investigated. The TBARS values of cold-dried slices increased from 42... | ['Air Movements', 'Animals', 'Cattle', 'Color', 'Desiccation', 'Food Handling', 'Humans', 'Odorants', 'Red Meat', 'Taste', 'Temperature', 'Thiobarbituric Acid Reactive Substances'] | 31,075,737 | [['G16.500.175.249', 'G16.500.275.063.725.154', 'N06.230.300.100.150.185'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G01.590.540.199'], ['E05.196.335', 'G02.176'], ['J01.576.423.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.500.275.640', 'N06.230.480'], ['G07.203.300.600.813', 'J02.500.60... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Immunoactive TSH in the amniotic fluid of the rat. | Amniotic fluid was obtained from 19-day-old rat fetuses by aspiration. Pooled samples measured at 4 different dilutions demonstrated parallelism with standard rat TSH. It is concluded that rat amniotic fluid has TSH immunoactivity. | ['Amniotic Fluid', 'Animals', 'Female', 'Pregnancy', 'Radioimmunoassay', 'Rats', 'Rats, Inbred Strains', 'Thyrotropin'] | 6,723,932 | [['A12.098', 'A16.378.149'], ['B01.050'], ['G08.686.784.769'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D06.472.699.631.525.883', 'D12.644.548.691.525.883']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulation of the effects of mutations in the basic region of the OmpA signal peptide by the mature portion of the protein. | Oligonucleotide-directed site-specific mutagenesis was used to study the structure-function relationship of the positively charged amino terminus of the Escherichia coli outer membrane protein OmpA signal peptide. Mutations were isolated which reduced the overall charge of the amino-terminal region from +2 (wild type) ... | ['Amino Acid Sequence', 'Bacterial Outer Membrane Proteins', 'Base Sequence', 'Escherichia coli', 'Genes', 'Genes, Bacterial', 'Kinetics', 'Molecular Sequence Data', 'Mutation', 'Protein Sorting Signals', 'beta-Lactamases'] | 3,292,525 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097.120', 'D12.776.543.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G01.37... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A phylogenomic analysis of turtles. | Molecular analyses of turtle relationships have overturned prevailing morphological hypotheses and prompted the development of a new taxonomy. Here we provide the first genome-scale analysis of turtle phylogeny. We sequenced 2381 ultraconserved element (UCE) loci representing a total of 1,718,154bp of aligned sequence.... | ['Animals', 'Bayes Theorem', 'Conserved Sequence', 'Likelihood Functions', 'Phylogeny', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Turtles'] | 25,450,099 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G02.111.570.580'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.400'], ['G05.697', 'G16.075.605', 'L01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations. | BACKGROUND: A gene on chromosome 9p, p16INK4, has been implicated in the pathogenesis of cutaneous malignant melanoma in 19 melanoma-prone families. In 10 of these kindreds mutations that impaired the function of the p16INK4 protein (p16M alleles) cosegregated with the disease. By contrast, in the other nine kindreds t... | ['Adult', 'Alleles', 'Chromosomes, Human, Pair 9', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Melanoma', 'Mutation', 'Neoplastic Syndromes, Hereditary', 'Pancreatic Neoplasms', 'Pedigree', 'Prospective Studies', 'Risk', 'Skin Neoplasms'] | 7,666,916 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['A11.284.187.520.300.325.345', 'G05.360.162.520.300.325.345'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['G05.365.590'], ['C04.700', 'C16.320.700'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glycinebetaine accumulation is more effective in chloroplasts than in the cytosol for protecting transgenic tomato plants against abiotic stress. | Tomato (Lycopersicon esculentum Mill. cv. Moneymaker) plants were transformed with a gene for choline oxidase (codA) from Arthrobacter globiformis. The gene product (CODA) was targeted to the chloroplasts (Chl-codA), cytosol (Cyt-codA) or both compartments simultaneously (ChlCyt-codA). These three transgenic plant type... | ['Alcohol Oxidoreductases', 'Arthrobacter', 'Betaine', 'Catalase', 'Chloroplasts', 'Cold Temperature', 'Cytosol', 'Germination', 'Hydrogen Peroxide', 'Lycopersicon esculentum', 'Oxidative Stress', 'Photosystem II Protein Complex', 'Plant Leaves', 'Plant Proteins', 'Plants, Genetically Modified', 'Protein Transport', 'S... | 17,617,827 | [['D08.811.682.047'], ['B03.510.024.850.050', 'B03.510.460.400.400.049.074'], ['D02.092.877.883.077', 'D02.675.276.125'], ['D08.811.682.732.332'], ['A11.284.430.214.190.875.700.140'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ideal Positions: 3D Sonography, Medical Visuality, Popular Culture. | As digital technologies are integrated into medical environments, they continue to transform the experience of contemporary health care. Importantly, medicine is increasingly visual. In the history of sonography, visibility has played an important role in accessing fetal bodies for diagnostic and entertainment purposes... | ['Culture', 'Female', 'Fetus', 'Humans', 'Imaging, Three-Dimensional', 'Pregnancy', 'Ultrasonography, Prenatal'] | 26,164,291 | [['I01.076.201.450', 'I01.880.853.100'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['G08.686.784.769'], ['E01.370.350.850.865', 'E01.370.378.630.865']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Simultaneous injection of hepatitis B vaccine with BCG and killed poliovirus vaccine. | In most developing countries, hepatitis B virus is endemic and prevention has to be carried out early in life and on a mass scale. In these regions, simultaneous administration of multiple antigens is normal practice. We have therefore investigated the interaction of hepatitis B vaccine with BCG and inactivated polio v... | ['BCG Vaccine', 'Hepatitis B Vaccines', 'Humans', 'Immunization', 'Infant, Newborn', 'Poliovirus Vaccine, Inactivated', 'Vaccines, Inactivated', 'Viral Hepatitis Vaccines'] | 1,533,479 | [['D20.215.894.135.825.100'], ['D20.215.894.899.955.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['M01.060.703.520'], ['D20.215.894.830.614', 'D20.215.894.899.623.500'], ['D20.215.894.830'], ['D20.215... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Baroreflex sensitivity and sympatho-vagal balance during intradialytic hypotensive episodes. | OBJECTIVES: The role of the baroreflex function in the pathogenesis of hemodialysis-associated hypotension is controversial. Complex demodulation technique (CDM), providing continuous assessment of the amplitude of cardiovascular oscillation over time, is particularly suitable to assess dynamic changes in autonomic ner... | ['Adult', 'Aged', 'Autonomic Nervous System', 'Baroreflex', 'Blood Pressure', 'Female', 'Heart Rate', 'Humans', 'Hypotension', 'Male', 'Middle Aged', 'Models, Cardiovascular', 'Renal Dialysis', 'Risk Factors', 'Sympathetic Nervous System', 'Vagus Nerve'] | 19,927,010 | [['M01.060.116'], ['M01.060.116.100'], ['A08.800.050'], ['G09.330.380.057', 'G11.561.731.063'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.514'], ['M01.060.116.630'], ['E05.599.395.161'], ['E02.870.300', 'E02.912.800... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cine-MRI detection of intraabdominal adhesions: correlation with intraoperative findings in 89 consecutive cases. | BACKGROUND: This study aimed to evaluate the accuracy of functional cine-MRI in detecting abdominal adhesions.METHODS: For this study, 89 consecutive patients with adhesion-related complaints after previous abdominal surgery underwent preoperative workup including cine-MRI in transverse and sagittal orientations for a ... | ['Abdominal Cavity', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Laparoscopy', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Sensitivity and Specificity', 'Tissue Adhesions'] | 18,322,749 | [['A01.923.047.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E01.370.350.825.500.510'], ['M01.060.116.630'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.72... | ['Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Drug consumption in workers in France: a comparative study at a 10-year interval (1996 versus 1986). | This study compared drug consumption and associated social factors in workers in France between 1986 and 1996. The same transversal survey was performed in 1986 and 1996 using the same methodology by means of an anonymous questionnaire given to the subject and answered in the presence of an occupational physician. The ... | ['Adult', 'Drug Utilization', 'Female', 'France', 'Humans', 'Male', 'Middle Aged', 'Occupations', 'Odds Ratio', 'Risk Factors', 'Sex Distribution', 'Socioeconomic Factors'] | 10,360,343 | [['M01.060.116'], ['N04.452.706.477'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N01.824.547'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.830.600.600'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', '... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
C-reactive protein as a marker of the surgical stress reduction within an ERAS protocol (Enhanced Recovery After Surgery) in colorectal surgery: A prospective cohort study. | BACKGROUND: The aim of this study is to evaluate the effectiveness of an Enhanced Recovery After Surgery Protocol (ERAS) in relation to reduce the Systemic Inflammatory Response (SIR) to surgery using C-reactive protein (CRP) in the first (POD1), second (POD2) and third (POD3) postoperative day.METHODS: We enrolled 121... | ['Aged', 'Biomarkers', 'C-Reactive Protein', 'Cohort Studies', 'Colectomy', 'Colorectal Neoplasms', 'Digestive System Surgical Procedures', 'Diverticular Diseases', 'Female', 'Gastrointestinal Diseases', 'Humans', 'Inflammatory Bowel Diseases', 'Male', 'Prospective Studies', 'Retrospective Studies'] | 29,355,975 | [['M01.060.116.100'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.210.219'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fine mapping of restorer-of-fertility gene based on high-density genetic mapping and collinearity analysis in pepper (Capsicum annuum L.). | KEY MESSAGE: The pepper restorer-of-fertility (CaRf) gene was fine mapped based on conjoint analysis of recombinants and collinearity between the two pepper reference genomes. Capana06g003028, encoding an Rf-like PPR protein, was proposed as the strongest candidate for pepper CaRf based on sequence comparison and expre... | ['Amino Acid Sequence', 'Capsicum', 'Chromosome Mapping', 'Cytoplasm', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genetic Linkage', 'Genetic Markers', 'Phenotype', 'Plant Infertility', 'Polymorphism, Single Nucleotide'] | 31,863,157 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.908.500.145'], ['E05.393.183'], ['A11.284.430.214'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['G05.695'], ['G15.649'], ['G05.365.795.598']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Auditory arousal responses and thresholds during REM and NREM sleep of sleepwalkers and controls. | BACKGROUND: It has been suggested that sleepwalkers are more difficult to awaken from sleep than are controls. However, no quantified comparisons have been made between these two populations. The main goal of this study was to assess arousal responsiveness via the presentation of auditory stimuli (AS) in sleepwalkers a... | ['Acoustic Stimulation', 'Adult', 'Arousal', 'Auditory Threshold', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Polysomnography', 'Sleep Stages', 'Sleep, REM', 'Somnambulism'] | 22,341,611 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520.625'], ['F02.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Caesarean delivery of first prediagnosed COVID-19 pregnancy in Nigeria. | The COVID-19 pandemic is currently causing widespread infection and deaths around the world. Since the identification of the first case in Nigeria in February 2020, the number of confirmed cases has risen to over 9,800. Although pregnant women are not necessarily more susceptible to infection by the virus, changes to t... | ['Adult', 'COVID-19', 'Cesarean Section', 'Coronavirus Infections', 'Female', 'Humans', 'Nigeria', 'Pandemics', 'Pneumonia, Viral', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Pregnancy Outcome', 'Prenatal Diagnosis'] | 32,774,659 | [['M01.060.116'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['E04.520.252.500'], ['C01.925.782.600.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.190.565'], ['N06.850.290.200.600'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Role of interleukin-24 in the tumor-suppressive effects of interferon-â on melanoma. | BACKGROUND: Type 1 interferons (IFNs), including IFN-â, are widely used in adjuvant therapy for patients who undergo surgery for malignant melanoma to inhibit recurrence and in-transit metastasis. The precise mechanisms underlying the tumor-suppressive effects of IFN-â on melanoma are not yet completely understood.OBJE... | ['Apoptosis', 'Cell Line, Tumor', 'Cell Proliferation', 'Chemotherapy, Adjuvant', 'Genome-Wide Association Study', 'Humans', 'Interferon-beta', 'Interleukins', 'Melanoma', 'Oligonucleotide Array Sequence Analysis', 'Receptors, Interleukin', 'Recombinant Proteins'] | 31,070,806 | [['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['E02.186.170', 'E02.319.170'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.050.150.900.649.313.988.400.112.4... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ecology and geography of hemorrhagic fever with renal syndrome in Changsha, China. | BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) is an important public health problem in mainland China. HFRS is particularly endemic in Changsha, the capital city of Hunan Province, with one of the highest incidences in China. The occurrence of HFRS is influenced by environmental factors. However, few studies... | ['Animals', 'China', 'Disease Vectors', 'Ecology', 'Hantaan virus', 'Hemorrhagic Fever with Renal Syndrome', 'Humans', 'Mice', 'Models, Biological', 'Models, Statistical', 'Rain', 'Rats', 'Reproducibility of Results', 'Risk', 'Rodentia', 'Seasons', 'Temperature'] | 23,819,824 | [['B01.050'], ['Z01.252.474.164'], ['N06.850.335.188', 'N06.850.520.203.375'], ['H01.158.273.248', 'H01.277.249'], ['B04.820.480.750.440.400'], ['C01.925.782.147.420.400', 'C01.925.782.417.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395'], ['E05.318.740... | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-á, and CYP2E1. | Garlic oil (GO) has been shown to partially attenuate ethanol-induced fatty liver, but the underlying mechanisms remain unclear. The current study was designed to evaluate the protective effects of GO against ethanol-induced steatosis in vitro and in vivo, and to explore potential mechanisms by investigating the sterol... | ['Adipose Tissue', 'Allyl Compounds', 'Animals', 'Cells, Cultured', 'Cytochrome P-450 CYP2E1', 'Ethanol', 'Male', 'Mice', 'PPAR alpha', 'Sterol Regulatory Element Binding Protein 1', 'Sulfides'] | 22,138,249 | [['A10.165.114'], ['D02.455.326.271.122'], ['B01.050'], ['A11.251'], ['D08.244.453.491.375', 'D08.811.682.662.582.338', 'D08.811.682.690.708.170.450.375', 'D12.776.422.220.453.491.375'], ['D02.033.375'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.826.239.500'], ['D12.776.260.103.500.750.500', 'D12.776.260.1... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Too Many Languages in the ALPPS: Preventing Another Tower of Babel? | OBJECTIVES: To establish a "consensus" terminology of many variants of the ALPPS procedure.BACKROUND: The rapid development and dissemination of ALPPS with the availability of many variants has led to numerous neologisms, also leading to confusion and difficulties in comparing various experiences. The first expert meet... | ['Consensus', 'Embolization, Therapeutic', 'Hepatectomy', 'Humans', 'Laparoscopy', 'Ligation', 'Liver', 'Portal Vein', 'Registries', 'Terminology as Topic'] | 26,764,874 | [['F01.829.316.068', 'F02.463.785.373.433'], ['E02.520.360', 'E02.926.500'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E04.426'], ['A03.620'], ['A07.015.908.670.567'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effectiveness of cultural immersion and culture classes for enhancing nursing students' transcultural self-efficacy. | With diversity increasing in the United States, educators are struggling to find the most effective methods to prepare nursing students to care for diverse populations. This study's purpose was to determine the impact of immersion experiences and cultural classes on nursing students' transcultural competence. A pretest... | ['Case-Control Studies', 'Curriculum', 'Education, Nursing, Baccalaureate', 'Educational Measurement', 'Female', 'Humans', 'Male', 'Models, Educational', 'Models, Nursing', 'Self Efficacy', 'Statistics, Nonparametric', 'Surveys and Questionnaires', 'Transcultural Nursing', 'United States', 'Young Adult'] | 21,323,246 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['I02.158'], ['I02.358.462.316'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.545', 'I02.903.302'], ['E05.599.645'], ['F01.752.747.792.700'], ['E05.318.740.995', 'N05.715.360.750.760', 'N06.850.520.830.995'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Impact of antibiotic treatment intensity on long-term sepsis-associated kidney injury in a polymicrobial peritoneal contamination and infection model. | BACKGROUND/AIMS: Long-term kidney affections after sepsis are poorly understood. Animal models for investigating kidney damage in the late phase of disease progression are limited. The aim of this study was to investigate the impact of two antibiotic regimes on persistence of kidney injury after peritonitis.METHODS: Ki... | ['Acute Kidney Injury', 'Acute-Phase Proteins', 'Animals', 'Anti-Bacterial Agents', 'Bacterial Infections', 'Biomarkers', 'Coinfection', 'Kidney', 'Kidney Function Tests', 'Kidney Tubules', 'Lipocalin-2', 'Lipocalins', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Models, Animal', 'Oncogene Proteins', 'Peritoneal Cavity', 'Se... | 25,634,142 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['D12.776.124.050'], ['B01.050'], ['D27.505.954.122.085'], ['C01.150.252'], ['D23.101'], ['C01.218'], ['A05.810.453'], ['E01.370.390.400'], ['A05.810.453.736.560'], ['D12.776.124.050.475', 'D12.776.157.469.325', 'D12.776.624.664.700.123'], ['D12.776.157.469'], ['B01.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Collagen fiber recruitment: A microstructural basis for the nonlinear response of the posterior pole of the eye to increases in intraocular pressure. | Our goal was to quantify and characterize how the collagen fiber crimp waviness of the lamina cribrosa (LC) and peripapillary sclera (PPS) changes with intraocular pressure (IOP). Thirteen sheep (ovine) eyes were immersion and perfusion fixed while maintaining IOP at 0, 10, 15, 20, or 50 mmHg. Coronal optic nerve head ... | ['Animals', 'Collagen', 'Intraocular Pressure', 'Microscopy, Polarization', 'Optic Nerve', 'Sclera', 'Sheep'] | 29,574,185 | [['B01.050'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G14.440'], ['E01.370.350.515.624', 'E05.595.624'], ['A08.800.800.120.680'], ['A09.371.784'], ['B01.050.150.900.649.313.500.380.791']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization and pathogenicity of Alternaria spp. strains associated with grape bunch rot during post-harvest withering. | Alternaria is a fungal agent of grape bunch rot which occurs during withering, a process which produces passito style wines. Seven isolates of Alternaria spp. were characterized using morphological examination, genotypic analysis and pathogenicity. Six of these isolates produced conidiophores and conidia displaying spo... | ['Alternaria', 'DNA, Ribosomal Spacer', 'Fruit', 'Phylogeny', 'Polymorphism, Restriction Fragment Length', 'Random Amplified Polymorphic DNA Technique', 'Vitis'] | 24,974,273 | [['B01.300.381.075'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.365.795.595'], ['E05.393.620.500.687', 'E05.601.700'], ['B01.650.940.800.575.912.250.965.500']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Role of microglial activation and neuroinflammation in neurotoxicity of acrylamide in vivo and in vitro. | Acrylamide, a soft electrophile, is widely used in the industry and laboratories, and also contaminates certain foods. Neurotoxicity and neurodegenerative effects of acrylamide have been reported in humans and experimental animals, although the underlying mechanism remains obscure. Activation of microglia and neuroinfl... | ['Acrylamide', 'Animals', 'Cell Line', 'Cell Survival', 'Cerebral Cortex', 'Cytokines', 'Dose-Response Relationship, Drug', 'Environmental Pollutants', 'Inflammasomes', 'Inflammation', 'Male', 'Mice', 'Microglia', 'Neuroimmunomodulation', 'Neurotoxicity Syndromes', 'Rats, Wistar'] | 31,073,625 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['B01.050'], ['A11.251.210'], ['G04.346'], ['A08.186.211.200.885.287.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.888.284'], ['D05.500.224'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.500'], ['A0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of gene polymorphisms in the endoplasmic reticulum stress pathway on clinical outcomes of chemoradiotherapy in Chinese patients with nasopharyngeal carcinoma. | There is considerable inter-individual variabil¬ity in chemoradiotherapy responses in nasopharyngeal carcinoma (NPC) patients receiv¬ing the same or similar treatment protocols. In this study we evaluated the association between the gene polymorphisms in endoplasmic reticulum (ER) stress pathway and chemoradiation resp... | ['Adenosine Triphosphatases', 'Adult', 'Asian Continental Ancestry Group', 'Calnexin', 'Carcinoma', 'Cell Cycle Proteins', 'Chemoradiotherapy', 'Endoplasmic Reticulum Stress', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Polymorphism, Genetic', 'Receptors, Calciton... | 28,216,622 | [['D08.811.277.040.025'], ['M01.060.116'], ['M01.686.508.200'], ['D12.644.360.372.311', 'D12.776.157.125.412.311', 'D12.776.476.387.311', 'D12.776.503.295', 'D12.776.543.162'], ['C04.557.470.200'], ['D12.776.167'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['G04.434'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Improvement in seizure detection performance by automatic adaptation to the EEG of each patient. | An important problem in the use of automatic seizure detection during long-term epilepsy monitoring is that false detections can be very frequent, often because a paroxysmal but non-epileptiform pattern occurs repeatedly in a particular patient. We therefore introduce a method to reduce such patient-specific false seiz... | ['Automation', 'Brain', 'Electroencephalography', 'Epilepsy', 'Humans', 'Monitoring, Physiologic'] | 7,681,382 | [['J01.897.104'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520']] | ['Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Research and dissemination needs for ergonomics in agriculture. | In 1998, the National Institute for Occupational Safety and Health convened a conference of researchers interested in the ergonomics of agricultural workers. Participants included 20 representatives from universities, state governments, private agricultural and insurance companies, migrant worker organizations, agricul... | ["Agricultural Workers' Diseases", 'Attitude to Health', 'Cost-Benefit Analysis', 'Ergonomics', 'Focus Groups', 'Health Priorities', 'Humans', 'Musculoskeletal Diseases', 'National Institute for Occupational Safety and Health, U.S.', 'Occupational Health', 'Research', 'Risk Factors', 'United States'] | 12,500,960 | [['C24.080'], ['F01.100.150', 'N05.300.150'], ['N03.219.151.125'], ['F02.784.412', 'J01.293.556'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['N03.349.330', 'N05.300.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05'], ['I01.409.418.750.600.650.200.520', 'N03.540.348.500.500.600.650... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Time changes in new cases of ischaemic heart disease in general practice. | BACKGROUND: There are no recent studies of the presentation of ischaemic heart disease (IHD) in general practice. What information exists is derived from the secondary care setting, where seasonal and daily variation has been reported in admissions for IHD. There are epidemiological studies that show a falling incidenc... | ['Age Distribution', 'Aged', 'Family Practice', 'Female', 'Health Services Research', 'Humans', 'Incidence', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Morbidity', 'Myocardial Ischemia', 'Population Surveillance', 'Prevalence', 'Retrospective Studies', 'Seasons', 'Sex Distribution', 'Time Factors', 'United Kingdom... | 11,021,898 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['H02.403.340.500'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E05.31... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
A clinical, neurophysiological and behavioral study of female workers exposed to 1,1,1-trichloroethane. | Twenty-two female subjects working in a factory in which 1,1,1-trichloroethane was the only solvent used were investigated by means of clinical, neurophysiological and psychometric methods so that the neurotoxicity of the solvent could be evaluated. On the basis of the ambient air concentrations of 1,1,1-trichloroethan... | ['Adult', 'Air Pollutants', 'Air Pollutants, Occupational', 'Back Pain', 'Behavior', 'Environmental Exposure', 'Female', 'Gastrointestinal Diseases', 'Headache', 'Humans', 'Hydrocarbons, Chlorinated', 'Nervous System', 'Neurotic Disorders', 'Occupational Diseases', 'Psychological Tests', 'Psychoses, Substance-Induced',... | 139,679 | [['M01.060.116'], ['D27.888.284.101'], ['D27.888.284.101.268'], ['C23.888.592.612.107'], ['F01.145'], ['N06.850.460.350'], ['C06.405'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.439'], ['A08'], ['F03.080.550', 'F03.650'], ['C24'], ['F04.711'], ['C25.723.809', 'C25.775.746',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Constipation in the elderly from Northern Sardinia is positively associated with depression, malnutrition and female gender. | OBJECTIVES: Constipation is a common complaint in older adults. The rise in life expectancy may amplify the problem and increase social expenditure. We investigated the major risk factors associated with constipation in a large sample of elderly.METHODS: Outpatients from Northern Sardinia attending a Geriatric Unit bet... | ['Aged', 'Aged, 80 and over', 'Aging', 'Body Mass Index', 'Constipation', 'Depression', 'Female', 'Geriatric Assessment', 'Humans', 'Italy', 'Male', 'Malnutrition', 'Mental Status Schedule', 'Multivariate Analysis', 'Nutrition Assessment', 'Nutritional Status', 'Outpatients', 'Prospective Studies', 'Risk Factors', 'Sex... | 29,779,417 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.821.150'], ['F01.145.126.350'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Toxicosis in newborn pigs associated with cutaneous application of an aerosol spray containing chlorpyrifos. | Weakness, lethargy, ataxia, lateral recumbency, limb paddling, tremors, salivation, and diarrhea were observed in newborn pigs on a commercial swine farm. Many pigs became moribund and died. All had been treated with an aerosol wound spray containing 2.5% chlorpyrifos. A controlled study was undertaken to determine whe... | ['Aerosols', 'Animals', 'Animals, Newborn', 'Chlorpyrifos', 'Nervous System Diseases', 'Swine', 'Swine Diseases', 'Wound Infection'] | 2,447,044 | [['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['B01.050.050.282'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['C10'], ['B01.050.150.900.649.313.500.880'], ['C22.905'], ['C01.947']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isolation, structure determination, synthesis, and sensory activity of N-phenylpropenoyl-L-amino acids from cocoa (Theobroma cacao). | Application of chromatographic separation and taste dilution analyses recently revealed besides procyanidins a series of N-phenylpropenoyl amino acids as the key contributors to the astringent taste of nonfermented cocoa beans as well as roasted cocoa nibs. Because these amides have as yet not been reported as key tast... | ['Amides', 'Amino Acids', 'Aspartic Acid', 'Cacao', 'Chromatography, High Pressure Liquid', 'Cinnamates', 'Glutamic Acid', 'Humans', 'Isomerism', 'Molecular Structure', 'Seeds', 'Taste', 'Tyrosine'] | 15,969,528 | [['D02.065'], ['D12.125'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['B01.650.940.800.575.912.250.859.821.500.164'], ['E05.196.181.400.300'], ['D02.241.223.200'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.685', 'G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Oxytetracycline as a predisposing condition for chalkbrood in honeybee. | Antibiotics, particularly oxytetracycline, have been discussed as a possible predisposing condition in the appearance of chalkbrood in the honeybee (Apis mellifera L.). Nevertheless, the scientific data to support this belief have been insufficient. We have developed a method to study the effects of this antibiotic as ... | ['Analysis of Variance', 'Animals', 'Anti-Bacterial Agents', 'Bees', 'Larva', 'Onygenales', 'Oxytetracycline', 'Spores, Fungal'] | 15,504,590 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.954.122.085'], ['B01.050.500.131.617.720.500.500.875.387'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.300.107.650'], ['D02.455.426.559.847.562.900.600', 'D04.615.562.900.600'], ['A11.870.710', 'A19.374.500', 'B05.775.710'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Amphetamine and derivatives related death in the aspect of forensic toxicology]. | Amphetamine and derivatives are the crucial theme in the problems of forensic toxicology. The paper is based on the study of 20 cases of deaths in which amphetamine and/or derivatives were involved as the cause of death. Toxicological examinations of the autopsy specimens were performed with the use of HPLC/MS method i... | ['Adult', 'Amphetamine-Related Disorders', 'Female', 'Forensic Sciences', 'Humans', 'Male', 'Toxicology', 'Violence'] | 14,569,892 | [['M01.060.116'], ['C25.775.225', 'F03.900.225'], ['I01.198.780'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.891', 'H02.884'], ['I01.198.240.856', 'I01.880.735.900']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Fasting and nutrient-stimulated plasma peptide-YY levels are elevated in critical illness and associated with feed intolerance: an observational, controlled study. | INTRODUCTION: Delayed gastric emptying and feed intolerance occur frequently in the critically ill. In these patients, gastric motor responses to nutrients are disturbed. Peptide YY (PYY) slows gastric emptying. The aim of this study was to determine fasting and nutrient-stimulated plasma PYY concentrations and their r... | ['Adult', 'Cholecystokinin', 'Dietary Sucrose', 'Fasting', 'Food, Formulated', 'Gastric Emptying', 'Humans', 'Male', 'Middle Aged', 'Parenteral Nutrition', 'Peptide YY', 'Respiration, Artificial'] | 17,173,662 | [['M01.060.116'], ['D06.472.317.152', 'D12.644.120'], ['D09.301.831.250', 'D09.698.629.305.770.200', 'D09.947.500.250', 'D09.947.750.770.200', 'D27.720.372.300.353.609.750.250', 'G07.203.300.362.831.250', 'G07.203.300.514.500.400.700.750.250', 'J02.500.362.831.250', 'J02.500.514.500.400.700.750.250'], ['F01.145.407.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
[Plasmid resistance to antiseptics. Demonstration of methods]. | Susceptibility to chlorhexidine, benzalkonium chloride and mercury chloride was studied for 70 Gram negative strains (56 Enterobacteriaceae and 14 Pseudomonas aeruginosa) recovered from humans or animals. Minimal inhibitory concentration (MIC) was determined on solid agar (replica plating) and in a liquid medium (laser... | ['Anti-Infective Agents, Local', 'Benzalkonium Compounds', 'Chlorhexidine', 'Conjugation, Genetic', 'Enterobacteriaceae', 'Mercuric Chloride', 'Microbial Sensitivity Tests', 'Pseudomonas aeruginosa', 'R Factors'] | 3,937,134 | [['D27.505.954.122.187'], ['D02.092.877.096.040', 'D02.675.276.080'], ['D02.078.370.141.100'], ['G05.728.200'], ['B03.440.450.425', 'B03.660.250.150'], ['D01.210.450.150.525', 'D01.538.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['G05... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
â-cypermethrin-induced acute neurotoxicity in the cerebral cortex of mice. | A Type II pyrethroid pesticide â-cypermethrin is widely used in agriculture and domestic applications for pest control. However, the effect of â-cypermethrin on the glutamate neurotransmitter has not been well-documented. In the current study, mice were treated with 20, 40, or 80 mg/kg â-cypermethrin by a single oral g... | ['Acute Disease', 'Animals', 'Cerebral Cortex', 'Dose-Response Relationship, Drug', 'Female', 'Glutamate-Ammonia Ligase', 'Glutamic Acid', 'Insecticides', 'Male', 'Mice', 'Neurotoxicity Syndromes', 'Pyrethrins'] | 24,649,940 | [['C23.550.291.125'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['G07.690.773.875', 'G07.690.936.500'], ['D08.811.464.259.200.600'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D27.720.031.700.491', 'D27.888.723.491'], ['B01.050.150.900.649.313.992.635.505.500'], ['C10.720', 'C25.723.705'],... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of tofacitinib in treatment of alopecia universalis in two patients. | BACKGROUND: Autoimmune-triggered non-scarring hair loss is a feature of alopecia areata (AA). Initially patchy and often self-limited, severe hair loss forms include the complete loss of scalp hair or alopecia totalis (AT) and complete loss of all hair or alopecia universalis (AU). For AT and AU a reliable treatment ha... | ['Adult', 'Alopecia', 'Humans', 'Male', 'Piperidines', 'Pyrimidines', 'Pyrroles', 'Treatment Outcome'] | 27,306,107 | [['M01.060.116'], ['C17.800.329.937.122', 'C23.300.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.621'], ['D03.383.742'], ['D03.383.129.578'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Human renal allograft blood flow and early renal function. | Renal allograft blood flow (RBF) was measured at operation by electromagnetic flow meter and probes in 45 patients (34 cadaver donors and 11 living related donors). Mean RBF in 26 patients without acute tubular necrosis (ATN), was 412 +/- 80 ml/min and in 19 patients with ATN, 270 +/- 100 ml/min (p less than .001). Onl... | ['Adolescent', 'Adult', 'Child', 'Female', 'Humans', 'Kidney', 'Kidney Transplantation', 'Kidney Tubules', 'Male', 'Middle Aged', 'Necrosis', 'Regional Blood Flow', 'Transplantation, Homologous'] | 335,986 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['A05.810.453.736.560'], ['M01.060.116.630'], ['C23.550.717'], ['G09.330.100.780'], ['E04.936.864']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Epidemiologic surveillance of occupational cancer in the light of the new law (DLgs 81/2008)]. | As a result of legislation regarding the surveillance of occupational cancers in Italy three systems for the monitoring of the effects of occupational exposure to carcinogenic agents have been implemented: - theMesothelioma national register (ReNaM), one of the most important experiences in terms of quality of data pro... | ['Adenocarcinoma', 'Carcinogens', 'Humans', 'Incidence', 'Italy', 'Mesothelioma', 'Neoplasms', 'Occupational Diseases', 'Occupational Exposure', 'Occupational Medicine', 'Paranasal Sinus Neoplasms', 'Registries', 'Surveys and Questionnaires', 'Workplace'] | 20,124,647 | [['C04.557.470.200.025'], ['D27.888.569.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.542.489'], ['C04.557.470.035.510', 'C04.557.470.660.510'], ['C04'], ['C24'], ['N06.850.460.350.600'], ['... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
The effect of lithium on the permeability response induced in the collecting duct by antidiuretic hormone. | The diffusional and osmotic water permeability of collecting ducts in isolated papillae of rats' kidneys were measured in papillae taken from normal and lithium pretreated rats. The diffusional water permeability of collecting ducts in papillae from normal rats in the absence of ADH was 4.1 +/- 0.2 (S.E.M.) (n = 18) mu... | ['Animals', 'Cell Membrane Permeability', 'Cyclic AMP', 'Diabetes Insipidus', 'Kidney Concentrating Ability', 'Kidney Medulla', 'Lithium', 'Rats', 'Vasopressins', 'Water'] | 185,585 | [['B01.050'], ['G03.143.335', 'G04.175'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['C12.777.419.135', 'C13.351.968.419.135', 'C19.700.159'], ['G08.852.536'], ['A05.810.453.466'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['B01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of the Lumipulse G TP-N Chemiluminescent Immunoassay as a Syphilis Screening Test. | A syphilis diagnosis is often aided by the detection of treponemal and nontreponemal antibodies. Automated treponemal antibody detection systems enable high-volume clinical laboratories to perform syphilis screening at a faster pace with lower labor costs. The Lumipulse G TP-N chemiluminescent immunoassay is an automat... | ['Antibodies, Bacterial', 'Automation, Laboratory', 'Diagnostic Errors', 'Diagnostic Tests, Routine', 'Humans', 'Immunoassay', 'Immunoglobulin G', 'Immunoglobulin M', 'Luminescent Measurements', 'Mass Screening', 'Syphilis', 'Time Factors', 'Treponema pallidum'] | 28,878,003 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['E05.064', 'J01.897.104.416'], ['E01.354', 'N02.421.450.280'], ['E01.370.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.6... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogs. | JP4-039 is a novel nitroxide conjugate capable of crossing lipid bilayer membranes and scavenging reactive oxygen species (ROS). An efficient and scalable one-pot hydrozirconation-transmetalation-imine addition methodology has been developed for its asymmetric preparation. Furthermore, this versatile methodology allows... | ['Amines', 'Esters', 'Models, Molecular', 'Molecular Structure', 'Nitrogen Oxides', 'Stereoisomerism'] | 21,452,836 | [['D02.092'], ['D02.241.400'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D01.362.635', 'D01.625.550', 'D01.650.550.587'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An in vitro model for the exposure of lung alveolar epithelial cells to toxic gases. | An in vitro model of lung alveolar tissue was developed by growing rat lung epithelial cells of Type II origin on hydrated collagen gels and subsequently maintaining the cultures at an air/liquid interface. The cultures provide a system to expose lung cells directly to toxic aerosols, fumes and gases. Nitrogen dioxide ... | ['Aerosols', 'Animals', 'Cell Survival', 'Clone Cells', 'Dose-Response Relationship, Drug', 'Epithelial Cells', 'Epithelium', 'In Vitro Techniques', 'Lysine', 'Microscopy, Electron, Scanning', 'Nitrogen Dioxide', 'Pulmonary Alveoli', 'Rats', 'Rats, Inbred F344', 'Time Factors'] | 3,098,954 | [['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['G04.346'], ['A11.251.353'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436'], ['A10.272'], ['E05.481'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.362.635.600', 'D01.625.550.525', 'D01.650.550.58... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bovine hydrocephalus in North Dakota: a survey and morphologic study. | A survey of hydrocephalus in cattle in North Dakota in 1975 and 1976 included 26 proven cases falling into categories comparable to that seen in the human situation. The largest group was hydrocephalus secondary to aqueductal stenosis with the second largest group being hydranencephaly. Other groups included the Dandy-... | ['Animals', 'Cattle', 'Cattle Diseases', 'Cerebral Aqueduct', 'Constriction, Pathologic', 'Hydranencephaly', 'Hydrocephalus', 'North Dakota'] | 847,630 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A08.186.211.132.659.413.875.187', 'A08.186.211.140.187'], ['C23.300.287'], ['C10.500.450', 'C16.131.666.450'], ['C10.228.140.602'], ['Z01.107.567.875.510.525']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Engaged urokinase receptors enhance tumor breast cell migration and invasion by upregulating alpha(v)beta5 vitronectin receptor cell surface expression. | We have previously shown that urokinase receptor physically and functionally interacts with alpha(v)beta5 vitronectin receptor, leading to tumor breast cell migration and invasion. Here, the link between these 2 receptors was further investigated by analyzing the expression levels of urokinase receptor and alpha(v)beta... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Cell Movement', 'Female', 'Humans', 'Immunohistochemistry', 'Integrin alphaVbeta3', 'Middle Aged', 'Neoplasm Invasiveness', 'Receptors, Cell Surface', 'Receptors, Urokinase Plasminogen Activator', 'Up-Regulation', 'Urokinase-Type Plasminogen Activator'] | 12,447,996 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['G04.198', 'G07.568.500.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.51... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibitor-1 phosphatase activity in vascular smooth muscle. | The histone-H1 and polylysine stimulated "latent" phosphorylase phosphatase, characterized by a molecular weight of 260,000 in gel filtration and 130,000 in sucrose density gradient centrifugation has been identified as a major inhibitor-1 phosphatase in vascular smooth muscle. Its substrate: protein phosphatase inhibi... | ['Animals', 'Aorta', 'Carrier Proteins', 'Cattle', 'Centrifugation, Density Gradient', 'Chromatography, Gel', 'Cyclic AMP', 'Histones', 'Intracellular Signaling Peptides and Proteins', 'Mercaptoethanol', 'Molecular Weight', 'Muscle, Smooth, Vascular', 'Phosphoprotein Phosphatases', 'Phosphorylase Phosphatase', 'Protein... | 6,329,166 | [['B01.050'], ['A07.015.114.056'], ['D12.776.157'], ['B01.050.150.900.649.313.500.380.271'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.196.181.400.250'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemodynamic effects of vasodilators across iliac stenoses in dogs. | Blood flow and pressure gradients were measured in dogs across externally applied iliac artery stenoses following 3 minutes of reactive hyperemia and injection of tolazoline (0.4 mg/kg), papaverine (0.04 mg/kg), and prostaglandin E1 (0.033 micrograms/kg) into the iliac artery. Stenoses of borderline and definite hemody... | ['Animals', 'Aorta', 'Arterial Occlusive Diseases', 'Dogs', 'Femoral Artery', 'Hindlimb', 'Hyperemia', 'Iliac Artery', 'Ischemia', 'Regional Blood Flow', 'Systole', 'Vasodilator Agents'] | 528,165 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of metal opaquer on the final color of 3 ceramic crown types on 3 abutment configurations. | STATEMENT OF PROBLEM: The effect of a recently introduced metal opaquer when used to mask the color of a titanium abutment under ceramic crown systems is unknown.PURPOSE: The purpose of this study was to compare the color coordinates of 3 ceramic crown types-characterized monolithic lithium disilicate (LDC) (IPS e.max;... | ['Ceramics', 'Computer-Aided Design', 'Crowns', 'Dental Abutments', 'Dental Implant-Abutment Design', 'Dental Materials', 'Dental Prosthesis Design', 'Humans', 'Prosthesis Coloring', 'Titanium'] | 29,724,553 | [['J01.637.153'], ['L01.224.108.150', 'L01.296.110.150'], ['E06.780.346.250', 'E07.695.190.088'], ['E06.780.346.500', 'E07.695.190.175'], ['E06.780.346.625.500', 'E06.912.145.750'], ['D25.339', 'D27.720.102.339', 'J01.637.051.339'], ['E06.780.346.625', 'E06.912.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Evidence for multiple routes of speech production in a case of fluent aphasia. | A case study is reported of a 24-year old woman who developed fluent aphasia with superior reading relative to auditory comprehension following herpes simplex encephalitis. Her language disturbance showed exceptional features: oral reading, repetition and naming to confrontation were severely impaired and yet her spont... | ['Adult', 'Aphasia, Wernicke', 'Electroencephalography', 'Encephalitis, Viral', 'Female', 'Herpes Simplex', 'Humans', 'Intelligence Tests', 'Language Tests', 'Memory', 'Neuropsychological Tests', 'Space Perception', 'Speech', 'Speech Perception', 'Speech Production Measurement', 'Tomography, X-Ray Computed', 'Visual Pe... | 8,800,611 | [['M01.060.116'], ['C10.597.606.150.500.800.100.166', 'C23.888.592.604.150.500.800.100.166'], ['E01.370.376.300', 'E01.370.405.245'], ['C01.207.245.340', 'C01.207.399.750', 'C01.925.182.525', 'C10.228.140.430.520.750', 'C10.228.228.245.340', 'C10.228.228.399.750'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.83... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Portable Health Care Facilities in Disaster and Rescue Zones: Characteristics and Future Suggestions. | IntroductionNatural and man-made disasters are becoming global concerns. Natural disasters appear to be growing in number and intensity due to global warming, population explosion, increased travel, and overcrowding of cities. In addition, man-made disasters do not seem to be diminishing.At disaster sites, an immediate... | ['Disaster Planning', 'Disasters', 'Emergency Medical Services', 'Forecasting', 'Humans', 'Mobile Health Units'] | 30,001,767 | [['N06.230.100.035'], ['N06.230.100'], ['N02.421.297'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.421.702', 'N02.421.726.233.628']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting. | High overexpression of somatostatin receptors in neuroendocrine tumors allows imaging and radiotherapy with radiolabeled somatostatin analogues. To ascertain whether a tumor is suitable for in vivo somatostatin receptor targeting, its somatostatin receptor expression has to be determined. There are specific indications... | ['Antibodies, Monoclonal', 'Autoradiography', 'Humans', 'Immunohistochemistry', 'Neoplasms', 'Receptors, Somatostatin', 'Retrospective Studies'] | 22,251,942 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Immunological and non-immunological release of leukotrienes and histamine from human nasal polyps. | Nasal polyps were obtained from 22 patients undergoing polyp surgery. They were chopped into fragments of approximately 2 mm2, washed free of blood, and passively sensitized with serum from timothy allergen sensitive patients (RAST 30-40%), then, challenged with timothy allergen. Analysis of the incubation medium after... | ['Allergens', 'Arachidonic Acid', 'Arachidonic Acids', 'Calcimycin', 'Chromatography, High Pressure Liquid', 'Histamine Release', 'Humans', 'Nasal Polyps', 'SRS-A', 'Time Factors'] | 2,423,281 | [['D23.050.063'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['D03.633.100.221.173'], ['E05.196.181.400.300'], ['G12.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.460.572', 'C09.603.557', 'C23.300.825.557'], ['D10.251.355.255.100.450.855', 'D1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oscillating behavior of carbohydrate granule formation and dinitrogen fixation in the cyanobacterium Cyanothece sp. strain ATCC 51142. | It has been shown that some aerobic, unicellular, diazotrophic cyanobacteria temporally separate photosynthetic O2 evolution and oxygen-sensitive N2 fixation. Cyanothece sp. ATCC strain 51142 is an aerobic, unicellular, diazotrophic cyanobacterium that fixes N2 during discrete periods of its cell cycle. When the bacter... | ['Carbohydrate Metabolism', 'Circadian Rhythm', 'Cyanobacteria', 'Inclusion Bodies', 'Microscopy, Electron', 'Nitrogen Fixation'] | 8,132,452 | [['G02.111.158', 'G03.191'], ['G07.180.562.190'], ['B03.280', 'B03.440.475.100'], ['A11.284.420'], ['E01.370.350.515.402', 'E05.595.402'], ['G02.111.071.630', 'G02.111.587.750', 'G02.607.560.750', 'G03.087.630', 'G06.625', 'G16.500.768.600']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physician Burnout and Barriers to Care on Professional Applications. | We surveyed New York physicians to study their perceptions of reporting requirements related to their own mental health care on professional applications, including whether they were experiencing symptoms of burnout. Over half of the responding physicians reported experiencing symptoms of burnout and these physicians w... | ['Attitude of Health Personnel', 'Burnout, Professional', 'Credentialing', 'Health Care Surveys', 'Humans', 'Job Application', 'Licensure, Medical', 'Mandatory Reporting', 'Mental Health', 'New York', 'Physicians', 'Societies, Medical'] | 31,626,578 | [['F01.100.050', 'N05.300.100'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['N03.706.110', 'N05.700.200'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.677.400'], ['N03... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Endogenous regulation of 2-deoxyglucose uptake in C6 glioma cells correlates with cytoskeleton-mediated changes of surface morphology. | The cellular basis of the membrane-limited state of glucose utilization and the mechanism of the endogenous regulation of hexose uptake in dense monolayers of C6 glioma cells were investigated. In an earlier study, it was shown that at high rates of glucose transport and phosphorylation combined with the inhibition of ... | ['Actins', 'Adenosine Triphosphate', 'Cell Line', 'Cell Membrane', 'Cells, Cultured', 'Chromatography, Ion Exchange', 'Cytoskeleton', 'Deoxy Sugars', 'Deoxyglucose', 'Dinitrophenols', 'Glioma', 'Hexoses', 'Microvilli', 'Spectrophotometry'] | 2,738,110 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.251.210'], ['A11.284.149'], ['A11.251'], ['E05.196.181.400.383'], ['A11.284.430.214.190.750'], ['D09.254'], ['D09.254.229'], ['D02.455.426.559.389.657.566.304', 'D... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urinary Tract Conditions Affect Fosfomycin Activity against Escherichia coli Strains Harboring Chromosomal Mutations Involved in Fosfomycin Uptake. | The steps by which Escherichia coli strains harboring mutations related to fosfomycin (FOS) resistance arise and spread during urinary tract infections (UTIs) are far from being understood. The aim of this study was to evaluate the effects of urine, pH, and anaerobiosis on FOS activity against a set of isogenic strains... | ['Anti-Bacterial Agents', 'Chromosomes, Bacterial', 'Escherichia coli', 'Escherichia coli Infections', 'Fosfomycin', 'Humans', 'Microbial Sensitivity Tests', 'Mutation', 'Urinary Tract', 'Urinary Tract Infections', 'beta-Lactamases'] | 29,038,268 | [['D27.505.954.122.085'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['D02.705.429.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G05.365.590'], ['A05.81... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Association between Metabolic Syndrome, Bone Mineral Density, Hip Bone Geometry and Fracture Risk: The Rotterdam Study. | The association between metabolic syndrome (MS) and bone health remains unclear. We aimed to study the association between MS and hip bone geometry (HBG), femoral neck bone mineral density (FN-BMD), and the risk of osteoporosis and incident fractures. Data of 2040 women and 1510 men participants in the third visit (199... | ['Aged', 'Aged, 80 and over', 'Bone Density', 'Female', 'Hip Fractures', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Osteoporosis', 'Pelvic Bones'] | 26,066,649 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G11.427.100'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['C05.116.198.579', 'C18.452.104.579'], ['A02.835.232.043.825']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[RATIONAL THERAPY FOR RECURRENT INFECTIONS OF THE LOWER URINARY TRACT. THE RESULTS OF A PROSPECTIVE OBSERVATIONAL PROGRAM TO ASSESS THE EFFECTIVENESS AND SAFETY OF CEFORAL®, SOLUTAB®* AND URO-VAKSOM® IN PATIENTS WITH RECURRENT UNCOMPLICATED LOWER URINARY TRACT INFECTIONS (FLORA)]. | Remaining generally unchanged, urinary tract infection (UTI) treatment protocols require continuing monitoring due to growing antibiotic resistance and lowered immune status of the majority of patients. The article presents the results of a prospective observational program carried out the Russian Federation in to asse... | ['Acyclovir', 'Adult', 'Anti-Bacterial Agents', 'Antiviral Agents', 'Cefixime', 'Female', 'Humans', 'Middle Aged', 'Urinary Tract Infections'] | 26,665,758 | [['D03.633.100.759.758.399.454.250'], ['M01.060.116'], ['D27.505.954.122.085'], ['D27.505.954.122.388'], ['D02.065.589.099.249.190.190.115', 'D02.886.665.074.190.190.115', 'D03.633.100.300.249.190.190.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.915', 'C12.777.892', 'C13.351.968.89... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Crystal structure of the N-terminal region of human Topoisomerase IIâ binding protein 1. | Human DNA Topoisomerase IIâ binding protein 1 (TopBP1) is a modulating protein that plays an essential role in the response to DNA damage. The N-terminal region of TopBP1, which contains predicted BRCA1-carboxy terminal (BRCT) domains 1 and 2, binds to Rad9, a component of the cell cycle checkpoint clamp Rad9-Hus1-Rad1... | ['BRCA1 Protein', 'BRCA2 Protein', 'Carrier Proteins', 'Crystallography, X-Ray', 'DNA-Binding Proteins', 'Enzyme Inhibitors', 'Humans', 'Nuclear Proteins', 'Phosphorylation', 'Protein Binding', 'Protein Structure, Tertiary', 'Serine'] | 20,858,457 | [['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['D12.776.313.249', 'D12.776.624.776.101', 'D12.776.660.105'], ['D12.776.157'], ['E05.196.309.742.225'], ['D12.776.260'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['G02.111... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Natural killer-like T-cell lymphoma of the small intestine with a distinct immunophenotype and lack of association with gluten-sensitive enteropathy. | We report the case of a large natural killer (NK)-like T-cell lymphoma that involved the ileum and displayed a distinct immunophenotype and complex karyotype. The patient exhibited no evidence of gluten-sensitive enteropathy (celiac disease) or any other type of enteropathy as determined by clinical history, endoscopy,... | ['Antigens, CD', 'Biomarkers', 'Biomarkers, Tumor', 'Celiac Disease', 'Humans', 'Immunophenotyping', 'Intestinal Neoplasms', 'Intestine, Small', 'Killer Cells, Natural', 'Lymphoma, T-Cell', 'Male', 'Middle Aged', 'Phenotype'] | 12,653,603 | [['D23.050.301.264.035', 'D23.101.100.110'], ['D23.101'], ['D23.101.140'], ['C06.405.469.637.250', 'C18.452.603.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['C04.588.274.476.411', 'C06.301.371.411', 'C06.405.249.411', 'C06.405.469.491'], ['A03.5... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spinal cord injury in partial Down syndrome. | Spinal cord injury is well documented in Down syndrome, and is commonly associated with atlantoaxial instability and ligamentous laxity. A case of partial Down syndrome is presented in which a cervical spine injury resulted in an incomplete quadriplegia. Possible factors leading to increased risk of SCI in partial Down... | ['Adolescent', 'Age Factors', 'Down Syndrome', 'Female', 'Humans', 'Quadriplegia', 'Risk', 'Spinal Cord Injuries'] | 2,956,936 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.622.760', 'C23.888.592.636.786'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of four treadmill protocols for determination of maximum oxygen uptake in 10- to 12-year-old boys. | Little information is available regarding the relative effectiveness of various treadmill exercise protocols in eliciting maximal oxygen consumption (VO2 max) values in children. In this study of 10- to 12-year-old boys, running protocols produced significantly higher VO2 max levels compared with walking, but there wer... | ['Child', 'Exercise Test', 'Heart Rate', 'Humans', 'Locomotion', 'Male', 'Oxygen Consumption', 'Physical Fitness', 'Running'] | 3,557,780 | [['M01.060.406'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568.500', 'G11.427.410.568'], ['G03.680'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400.545'], ['G11.427.410.568.610', 'G11.427.410.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Fatal Canid herpesvirus 1 infection in an adult dog. | Canid herpesvirus 1 (CaHV-1) is a well-known cause of fatal hepatic and renal necrosis in neonatal puppies. In adult dogs infected with CaHV-1, papulovesicular genital lesions may be observed. CaHV-1 infection during pregnancy can lead to embryonic resorption, abortion, and stillbirth. In high-density dog populations, ... | ['Animals', 'DNA, Viral', 'Dog Diseases', 'Dogs', 'Fatal Outcome', 'Female', 'Herpesviridae Infections', 'Herpesvirus 1, Canid', 'Immunohistochemistry', 'In Situ Hybridization', 'Liver Diseases', 'Polymerase Chain Reaction'] | 22,529,135 | [['B01.050'], ['D13.444.308.568'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C01.925.256.466'], ['B04.280.382.100.900.420'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Selective attention to human voice enhances brain activity bilaterally in the superior temporal sulcus. | Regional cerebral blood flow was measured with positron emission tomography (PET) in 10 healthy male volunteers. They heard two binaurally delivered concurrent stories, one spoken by a male voice and the other by a female voice. A third story was presented at the same time as a text running on a screen. The subjects we... | ['Adult', 'Attention', 'Brain', 'Brain Mapping', 'Female', 'Functional Laterality', 'Hearing', 'Humans', 'Male', 'Positron-Emission Tomography', 'Radiography', 'Russia', 'Temporal Lobe', 'Voice'] | 16,460,705 | [['M01.060.116'], ['F02.830.104.214'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.830.297.425', 'G11.561.225.425'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.350.800.700', 'E01.370.350.600.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Comparative secretome analysis of human bone marrow-derived mesenchymal stem cells during osteogenesis. | Osteogenesis is a tightly regulated process that involves coordinated extracellular signals from autocrine and paracrine loops. Secretory proteins during osteogenesis can inhibit cell proliferation and activate cell differentiation toward mature osteoblasts, which are characterized by mineralization. In this study, we ... | ['Bone Marrow Cells', 'Computational Biology', 'Gene Expression Regulation', 'Humans', 'Mesenchymal Stem Cells', 'Osteogenesis', 'Proteome', 'Proteomics', 'Transcriptome'] | 22,674,502 | [['A11.148', 'A15.378.316'], ['H01.158.273.180', 'L01.313.124'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['D12.776.817'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.... | ['Anatomy [A]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Improving quality through performance-based financing in district hospitals in Rwanda between 2006 and 2010: a 5-year experience. | INTRODUCTION: Since 2000 performance-based financing (PBF) made its way to sub-Saharan health systems in an attempt to improve service delivery. In Rwanda initial experiences in 2001 and 2002 led to a scaling up of the initiative to all health centres (HC) and district hospitals (DH). In 2008 PBF became national strate... | ['Financing, Organized', 'Hospitals, District', 'Humans', 'National Health Programs', 'Quality Assurance, Health Care', 'Retrospective Studies', 'Rwanda'] | 25,406,257 | [['N03.219.521'], ['N02.278.421.510.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550'], ['N04.761.700', 'N05.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['Z... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Liposarcoma of the spermatic cord associated with rectum cancer: a case report]. | We report a case of liposarcoma of the spermatic cord associated with rectum cancer. A 78-year-old man visited our hospital with a complaint of painless left inguinal mass. He also showed constipation and bloody bowel discharge, rectum cancer was diagnosed by further evaluation. Ultrasonography, computed tomography and... | ['Adenocarcinoma', 'Aged', 'Fatal Outcome', 'Genital Neoplasms, Male', 'Humans', 'Liposarcoma', 'Magnetic Resonance Imaging', 'Male', 'Rectal Neoplasms', 'Spermatic Cord', 'Tomography, X-Ray Computed'] | 17,874,556 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C04.588.945.440', 'C12.294.260', 'C12.758.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.420', 'C04.557.450.795.465'], ['E01.370.3... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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