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Association of serum uric acid with all-cause and cardiovascular disease mortality and incident myocardial infarction in the MONICA Augsburg cohort. World Health Organization Monitoring Trends and Determinants in Cardiovascular Diseases. | Because previous findings have been inconsistent, we explored the association of serum concentrations of uric acid with all-cause and cardiovascular disease mortality and myocardial infarction prospectively. We used data from 1,044 men who are members of the World Health Organization Monitoring Trends and Determinants ... | ['Cardiovascular Diseases', 'Cause of Death', 'Cohort Studies', 'Germany', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Myocardial Infarction', 'Prospective Studies', 'Risk Factors', 'Uric Acid'] | 10,401,873 | [['C14'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.2... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Growth substrates and caleosin-mediated functions affect conidial virulence in the insect pathogenic fungus Beauveria bassiana. | The entomopathogenic fungus, Beauveria bassiana, is a microbial biological control agent capable of infecting a wide range of insect hosts. Conidia (spores) initiate infection via adhesion, growth and penetration of the insect cuticle, whose outmost layer is rich in lipids. Conidial virulence was investigated in B. bas... | ['Animals', 'Beauveria', 'Calcium-Binding Proteins', 'Culture Media', 'Fungal Proteins', 'Insecta', 'Plant Proteins', 'Spores, Fungal', 'Virulence'] | 27,655,425 | [['B01.050'], ['B01.300.107.501.100', 'B01.300.381.103'], ['D12.776.157.125'], ['D27.720.470.305', 'E07.206'], ['D12.776.354'], ['B01.050.500.131.617'], ['D12.776.765'], ['A11.870.710', 'A19.374.500', 'B05.775.710'], ['G06.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thalassemia in the outpatient department of the Yangon Children's Hospital in Myanmar: basic hematological values of thalassemia traits. | The present study was conducted in the Outpatient Department (OPD) of Yangon Children's Hospital (YCH) during June to November 1990 to determine the hematological data of 133 Myanmar patients with thalassemia trait who were the parents of patients with known beta-thalassemia major or hemoglobin E (Hb E)/beta-thalassemi... | ['Adolescent', 'Adult', 'Ambulatory Care', 'Erythrocyte Count', 'Erythrocyte Indices', 'Female', 'Hematologic Tests', 'Hospitals, Pediatric', 'Humans', 'Male', 'Middle Aged', 'Myanmar', 'Thalassemia'] | 1,439,979 | [['M01.060.057'], ['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.330', 'E05.242.195.107.330', 'G04.140.107.330', 'G09.188.105.330'], ['E01.370.225.625.230', 'E05.200.625.230', 'G09.188.260'], ['E01.370.225.625',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of the antialbuminuric effects of L-/N-type and L-type calcium channel blockers in hypertensive patients with diabetes and microalbuminuria: the study of assessment for kidney function by urinary microalbumin in randomized (SAKURA) trial. | OBJECTIVE: To clarify whether the L-/N-type calcium channel blocker (CCB) cilnidipine is more renoprotective than the L-type CCB amlodipine in patients with early-stage diabetic nephropathy.METHODS: In this prospective, multicenter, open-labeled, randomized trial, the antialbuminuric effects of cilnidipine and amlodipi... | ['Aged', 'Albuminuria', 'Amlodipine', 'Antihypertensive Agents', 'Blood Pressure', 'Calcium Channel Blockers', 'Calcium Channels, L-Type', 'Calcium Channels, N-Type', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Dihydropyridines', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Prospective Studie... | 23,935,398 | [['M01.060.116.100'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['D03.383.725.203.065'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.4... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
South-south collaboration on HIV/AIDS prevention and treatment research: when birds of a feather rarely flock together. | BACKGROUND: South-south collaboration on health and development research is a critical mechanism for social and economic progress. It allows sharing and replicating experiences to find a "southern solution" to meet shared health challenges, such as access to adequate HIV/AIDS prevention and treatment. This study aimed ... | ['Bibliometrics', 'Biomedical Research', 'Cooperative Behavior', 'Developing Countries', 'HIV Infections', 'Humans', 'Randomized Controlled Trials as Topic'] | 29,490,665 | [['L01.178.682.099.325', 'L01.453.183.291'], ['H01.770.644.145'], ['F01.145.813.115'], ['I01.615.500.300'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.250.250.365.500', 'N05.71... | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
In vitro activity of penicillins against anaerobes. | The in vitro susceptibility of 162 anaerobic isolates from clinical material were tested to pencillin G, BL-P1654, and carbenicillin. Penicillin G and BL-P1654 showed good activity against Bacteroides fragilis, but only 60% of strains were susceptible to carbenicillin at achievable blood levels (128 mug/ml). | ['Anaerobiosis', 'Bacteria', 'Penicillin Resistance', 'Penicillins'] | 1,041,215 | [['G02.111.062', 'G03.078'], ['B03'], ['G06.099.225.500.600', 'G06.225.347.500.600', 'G07.690.773.984.269.347.500.600'], ['D02.065.589.099.750', 'D02.886.108.750', 'D03.633.100.300.750']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Blood, urine, and hair kinetic analysis following an acute lead intoxication. | A case of lead exposure resulting from the accidental ingestion of a lead-containing solution is reported. Because of clinical management rapidly performed through chelation therapy by 2,3-dimercaptopropane sulfonate sodium and meso-2,3-dimercaptosuccinic acid, blood lead levels of this 51-year-old patient were moderat... | ['Chelating Agents', 'Chelation Therapy', 'Female', 'Hair', 'Humans', 'Kinetics', 'Lead', 'Lead Poisoning', 'Middle Aged', 'Succimer', 'Unithiol'] | 21,219,705 | [['D27.505.519.914.500', 'D27.720.832.500'], ['E02.319.155'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D01.268.556.435', 'D01.552.544.435'], ['C25.723.522.750'], ['M01.060.116.630'], ['D02.241.081.337.759.500', 'D02.886.489.750'], ['D02.886.489.180.900']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation and characterization of the tandemly repeated U6 genes from the sea urchin Strongylocentrotus purpuratus. | The tandemly repeated U6 genes were isolated from the sea urchin Strongylocentrotus purpuratus. Each 1.8 kb repeat unit contains a single U6 RNA sequence. There are no sequence similarities between the U6 promoter and other sea urchin snRNA genes, other than a long polypyrimidine tract 3' of the U6 sequence. | ['Animals', 'Caenorhabditis elegans', 'DNA Primers', 'Drosophila', 'Molecular Sequence Data', 'Multigene Family', 'Muridae', 'Polymerase Chain Reaction', 'RNA, Small Nuclear', 'Restriction Mapping', 'Sea Urchins', 'Sequence Homology, Nucleic Acid'] | 8,049,270 | [['B01.050'], ['B01.050.500.500.294.400.875.660.250.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['B01.050.150.900.649.313.992.635'], ['E05.393.620.500'], ['D13.444.735.628.818', 'D13.444.735.790.552... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison and Validation of Recommended QT Interval Correction Formulas for Predicting Cardiac Arrhythmias in Patients With Advanced Heart Failure and Cardiac Resynchronization Devices. | QT interval prolongation is an important marker for the development of cardiac arrhythmias (CAs). Optimal methods to estimate QT/QTc intervals in patients with ventricular pacing (VP) and its correlation with CA have not been widely investigated. We aimed to validate the currently available formulas for QT determinatio... | ['Aged', 'Arrhythmias, Cardiac', 'Cardiac Resynchronization Therapy Devices', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Heart Conduction System', 'Heart Failure', 'Humans', 'Incidence', 'Male', 'Prognosis', 'Retrospective Studies', 'Spain', 'Time Factors'] | 28,739,032 | [['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['E07.305.250.750.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A07.541.409'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Nutritional status and related factors among elderly Brazilians]. | OBJECTIVE: This study describes the nutritional status and associated factors among elderly Brazilians.METHODS: Data from "Pesquisa sobre Padr?es de Vida" (PPV- Life Pattern Research), conducted by the "Brazilian Geographic and Statistics Institute" in 1996/1997 were used. Body Mass Index (BMI) was applied to classify ... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Body Weight', 'Brazil', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nutrition Surveys', 'Nutritional Status', 'Obesity', 'Rural Population', 'Sex Factors', 'Socioeconomic Factors', 'Thinness', 'Urban Population'] | 16,967,137 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['Z01.107.757.176'], [... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Study on proteinase-inhibiting capacity of plasma alpha 2-macroglobulin in idiopathic nephrotic syndrome. | We studied the relationship between plasma alpha 2-macroglobulin (alpha 2M) and depressed cell-mediated immunity in idiopathic nephrotic syndrome (INS). Plasma alpha 2M concentrations (mumol/l) were increased during relapses of INS; however, the proteinase inhibitory activity, measured using bacterial thermolysin, was ... | ['Adolescent', 'Child', 'Child, Preschool', 'Chymotrypsin', 'Humans', 'Lymphocyte Activation', 'Mitogens', 'Nephrotic Syndrome', 'Protease Inhibitors', 'Thermolysin', 'alpha-Macroglobulins'] | 8,730,413 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['D27.505.519.593.624'], ['C12.777.419.630.643', 'C13.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
miR-216b inhibits glioma cell migration and invasion through suppression of FoxM1. | MicroRNAs (miRNAs) play a vital role in tumour biological and pathologic processes. In the present study, we aimed to detect the expression and biological role of miR-216b in glioma. Our data showed that miR-216b was significantly downregulated in human glioma tissues and cells. Ectopic expression of miR-216b inhibited... | ["3' Untranslated Regions", 'Animals', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Down-Regulation', 'Female', 'Forkhead Box Protein M1', 'Gene Expression Regulation, Neoplastic', 'Glioma', 'Humans', 'Male', 'Mice', 'Mice, Nude', 'MicroRNAs', 'Middle Aged', 'Neoplasm Invasiveness', 'Transfection'] | 28,731,180 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D12.776.260.950.249... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of lovastatin, clomazone and methyl jasmonate treatment on the accumulation of purpurin and mollugin in cell suspension cultures of Rubia cordifolia. | AIM: To determine the IPP origin of the naphthoquinones (NQs) in Rubia cordifolia, and to evaluate the effects of methyl jasmonate (MeJA) treatment, MEP, and MVA pathway inhibitor treatment on the accumulation of anthraquinones (AQs) and NQs in cell suspension cultures of R. cordifolia.METHODS: Cell suspension cultures... | ['Acetates', 'Anthraquinones', 'Cell Culture Techniques', 'Cells, Cultured', 'Cyclopentanes', 'Isoxazoles', 'Lovastatin', 'Oxazolidinones', 'Oxylipins', 'Pyrans', 'Rubia'] | 23,845,549 | [['D02.241.081.018', 'D10.251.400.045'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251'], ['D02.455.426.392.368.450'], ['D03.383.129.385'], ['D02.455.426.559.847.638.400', 'D04.615.638.400'], ['D03.383.129.462.6... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel procedure for the efficient purification of the cystic fibrosis transmembrane conductance regulator (CFTR). | This report describes a novel, single-step strategy for the purification of the cystic fibrosis transmembrane conductance regulator from Sf9 cells, which will facilitate studies of the structure-function relationships of this clinically important molecule. The new method combines the use of the novel detergent sodium p... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Animals', 'Caprylates', 'Cell Line', 'Chlorides', 'Chromatography, Affinity', 'Chromatography, Thin Layer', 'Cloning, Molecular', 'Cyclic AMP-Dependent Protein Kinases', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Detergents', 'Fluorocarbons', 'Humans... | 9,355,728 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D02.241.081.222', 'D10.251.122'], ['A11.251.210'], ['D01.210.450.150', 'D01.248.497.158.215'], ['E05.196.181.400.170'], ['E05.196.181.400.537'], ['E05.393.220'], ['D08.811.913.696.620.682.700.150.125'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Coiling phagocytosis discriminates between different spirochetes and is enhanced by phorbol myristate acetate and granulocyte-macrophage colony-stimulating factor. | The mechanisms involved in coiling phagocytosis are not yet known, and it is not even clear whether this phenomenon is either an incidental event or a specific response. Therefore, the phagocytic uptake of Borrelia burgdorferi and other spirochetes by human monocytes in vitro was used to investigate the involvement of ... | ['Borrelia burgdorferi Group', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Humans', 'Phagocytosis', 'Tetradecanoylphorbol Acetate'] | 9,453,619 | [['B03.440.425.410.711.193.150', 'B03.851.595.193.150'], ['D12.644.276.374.410.240.375', 'D12.776.395.240.300', 'D12.776.467.374.410.240.375', 'D23.529.374.410.240.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['D02.455.849.291.500.510.850']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urine vascular endothelial growth factor-A is not a useful marker for endometriosis. | OBJECTIVE: To determine whether urine VEGF is elevated in women with endometriosis.DESIGN: Prospective observational study.SETTING: Tertiary care government and private hospitals.PATIENT(S): During laparoscopy for pelvic pain or infertility, urine was collected and possible endometriosis lesions were excised. Of 62 wom... | ['Adult', 'Biomarkers', 'Case-Control Studies', 'Endometriosis', 'Female', 'Humans', 'Middle Aged', 'Prospective Studies', 'Vascular Endothelial Growth Factor A'] | 15,193,469 | [['M01.060.116'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['D12.644.276.100.800.200', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oral barium sulfate in partial large-bowel obstruction. | Nine dogs underwent a surgically created partial obstruction of the large bowel and were then given oral barium sulfate. The residual lumen of the obstructed portion varied from 4 to 10 mm in diameter. Clinical obstruction did not develop, and all dogs passed the barium sulfate in 1 to 16 days. This limited study plus ... | ['Animals', 'Barium Sulfate', 'Dogs', 'Duodenal Ulcer', 'Humans', 'Intestinal Obstruction', 'Intestine, Large', 'Male', 'Middle Aged', 'Radiography', 'Sigmoid Neoplasms', 'Time Factors'] | 7,403,505 | [['B01.050'], ['D01.103.075', 'D01.875.800.800.850.075'], ['B01.050.150.900.649.313.750.250.216.200'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['A03.556.124.526', 'A03.556.249.249'], ['M01.060.116.630'], ['E01.370.350.700'], ['C04.588.274... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Atosiban and nifedipin for the treatment of preterm labor. | OBJECTIVE: To perform a comparison between atosiban (oxytocin antagonist) and nifedipin (calcium channel blocker) for acute treatment of preterm labor and their maternal safety.METHODS: A randomized controlled trial study was performed on 80 pregnant women with preterm labor, between 26 and 34 weeks of pregnancy, in Ak... | ['Female', 'Humans', 'Nifedipine', 'Obstetric Labor, Premature', 'Oxytocics', 'Pregnancy', 'Tocolytic Agents', 'Vasotocin'] | 16,043,178 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.725.203.540'], ['C13.703.420.491'], ['D27.505.696.875.737', 'D27.505.954.705.737'], ['G08.686.784.769'], ['D27.505.696.875.825', 'D27.505.954.705.825'], ['D06.472.699.631.692.881', 'D12.644.548.691.692.881']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel approaches to preclinical research and TB vaccine development. | The 4th Global Forum on TB Vaccines, convened in Shanghai, China, from 21 - 24 April 2015, brought together a wide and diverse community involved in tuberculosis vaccine research and development to discuss the current status of, and future directions for this critical effort. This paper summarizes the sessions on Low-D... | ['Aerosols', 'BCG Vaccine', 'Clinical Trials as Topic', 'Drug Delivery Systems', 'Drug Design', 'Drug Discovery', 'Drug Evaluation, Preclinical', 'Histocompatibility Antigens Class I', 'Humans', 'Tuberculosis', 'Tuberculosis Vaccines', 'Vaccines, Attenuated', 'Vaccines, Synthetic'] | 27,452,413 | [['D20.280.055', 'D26.255.165.055'], ['D20.215.894.135.825.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.319.300'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['E05.290.750', 'E05.337.550'], ['D1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Epidemiology of spinal cord injuries in Novosibirsk, Russia. | The incidence of spinal cord injuries (SCI) in Novosibirsk is 29.7 per million per year. Almost all of these SCI patients (94.3%) are hospitalized to our clinic. Over the past 5 years (since 1989), a total of 196 patients with SCI were admitted. SCI were distributed as follows: cervical, 96 patients (49.0%); thoracic, ... | ['Adult', 'Age Factors', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Russia', 'Sex Factors', 'Spinal Cord Injuries'] | 7,644,257 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['Z01.252.122.500', 'Z01.542.248.775'], ['N05.715.350.675', 'N06.850.490.875']... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Flow cytometric analysis of cytokine receptors on human Langerhans' cells. Changes observed after short-term culture. | It is well established that granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-1 and tumour necrosis factor-alpha (TNF-alpha) are involved in Langerhans' cell (LC) development and dendritic cell traffic. However, little is known about the pattern of cytokine receptors on human LC and their modu... | ['Antibodies, Monoclonal', 'Cell Culture Techniques', 'Flow Cytometry', 'Humans', 'Kinetics', 'Langerhans Cells', 'Receptors, Cytokine', 'Receptors, Granulocyte-Macrophage Colony-Stimulating Factor', 'Receptors, Interferon', 'Receptors, Interleukin', 'Receptors, Tumor Necrosis Factor'] | 8,698,397 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improved tendon healing using bFGF, BMP-12 and TGFâ1 in a rat model. | Several growth factors (GFs) are expressed as tendons heal, but it remains unknown whether their combined application enhances the healing process. This matter was addressed by applying a combination of basic fibroblast growth factor (bFGF), bone morphogenetic protein 12 (BMP-12) and transforming growth factor beta 1 (... | ['Animals', 'Biomechanical Phenomena', 'Bone Morphogenetic Proteins', 'Collagen', 'Fibroblast Growth Factor 2', 'Horses', 'Male', 'Rats, Sprague-Dawley', 'Tendons', 'Transforming Growth Factor beta1', 'Weight-Bearing', 'Wound Healing'] | 29,897,097 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.313.984.235.472'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A02.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurotensin-induced antinociception and hypothermia in mice: antagonism by TRH and structural analogs of TRH. | Intracisternal (IC) administration of neurotensin (NT) in a dose of 10 micrograms produced a significant hypothermia and antinociception in the hot-plate test in mice. Both of these effects of IC NT were completely antagonized by concomitant administration of equimolar doses of thyrotropin-releasing hormone (TRH) and s... | ['Analgesia', 'Animals', 'Body Temperature', 'Hot Temperature', 'Hypothermia', 'Male', 'Mice', 'Neurotensin', 'Peptides', 'Reaction Time', 'Thyrotropin-Releasing Hormone'] | 6,425,994 | [['E03.091'], ['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['C23.888.119.565'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.400.550', 'D12.776.631.650.550'], ['D12.644'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Different mechanisms mediating tail-flick inhibition induced by beta-endorphin, DAMGO and morphine from ROb and GiA in anesthetized rats. | The effects of beta-endorphin, D-Ala2-NMePhe4-Gly-ol-enkephalin (DAMGO) and morphine microinjected into raphe obscurus nucleus (ROb) and gigantocellular reticular nucleus alpha (GiA) in inhibiting the tail-flick response were studied in pentobarbital anesthetized rats. beta-Endorphin (0.1-3 micrograms) microinjected in... | ['Analgesia', 'Animals', 'Brain Stem', 'Diffusion', 'Enkephalin, Ala(2)-MePhe(4)-Gly(5)-', 'Enkephalins', 'Male', 'Methysergide', 'Morphine', 'Naloxone', 'Raphe Nuclei', 'Rats', 'Rats, Inbred Strains', 'Yohimbine', 'beta-Endorphin'] | 2,020,008 | [['E03.091'], ['B01.050'], ['A08.186.211.132'], ['G01.202', 'G02.196'], ['D12.644.400.575.281.075', 'D12.776.631.650.575.281.075'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['D03.132.327.287.689', 'D03.633.400.439.689'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Periodontitis and perceived risk for periodontitis in elders with evidence of depression. | BACKGROUND: Depression and periodontitis are common conditions in older adults. There is some evidence that these two conditions may be related.AIMS: To study a population of dentate elders and assess the prevalence of depression, self-assessment of risk for periodontitis and tooth loss, in relation to periodontal dise... | ['Aged', 'Dental Care for Aged', 'Depression', 'Female', 'Geriatric Assessment', 'Humans', 'Logistic Models', 'Male', 'Periodontitis', 'Probability', 'Risk Factors', 'Self Disclosure', 'Statistics, Nonparametric', 'Tooth Loss'] | 12,887,337 | [['M01.060.116.100'], ['E06.170.100', 'N02.421.240.190.210'], ['F01.145.126.350'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Costs of preserved corneal transplants]. | BACKGROUND: Organ culture medium and Optisol are the most commonly used corneal storage mediums. This study compares the costs for these two methods.METHODS: In the calculation of costs we did not just take the direct costs into account, but also tried to determine the fixed costs per transplanted cornea with correspon... | ['Austria', 'Chondroitin Sulfates', 'Complex Mixtures', 'Corneal Transplantation', 'Cost-Benefit Analysis', 'Culture Media, Serum-Free', 'Dextrans', 'Gentamicins', 'Humans', 'Organ Culture Techniques', 'Organ Preservation'] | 9,432,238 | [['Z01.542.088'], ['D09.698.373.200.300'], ['D20'], ['E02.095.147.725.225', 'E04.540.825.374', 'E04.936.580.225'], ['N03.219.151.125'], ['D27.720.470.305.255', 'E07.206.255'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481.500.484'], ['E02.792... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[New trends in rabies vaccination]. | A brief review of the old and new proposed antirabies vaccines was treated. A better immunogenicity, safety and acceptability of the vaccines obtained from nonneural tissues was demonstrated. Some considerations about the human rabies pathogenesis and immunity were also briefly discussed. | ['Humans', 'Rabies', 'Rabies Vaccines', 'Vaccination'] | 7,247,480 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.782.580.830.750'], ['D20.215.894.899.700'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', 'N02.421.726.758.310.890', 'N06.850.780.200.425.900', 'N06.850.780.680.310.890']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
First report of two complete Clostridium chauvoei genome sequences and detailed in silico genome analysis. | Clostridium (C.) chauvoei is a Gram-positive, spore forming, anaerobic bacterium. It causes black leg in ruminants, a typically fatal histotoxic myonecrosis. High quality circular genome sequences were generated for the C. chauvoei type strain DSM 7528T (ATCC 10092T) and a field strain 12S0467 isolated in Germany. The ... | ['Bacteriophages', 'Base Composition', 'Clostridium Infections', 'Clostridium chauvoei', 'Clustered Regularly Interspaced Short Palindromic Repeats', 'Computational Biology', 'Drug Resistance, Bacterial', 'Genome, Bacterial', 'Genomics', 'Molecular Sequence Annotation', 'Open Reading Frames', 'Phylogeny', 'Replication ... | 28,720,440 | [['B04.123'], ['G02.111.080'], ['C01.150.252.410.222'], ['B03.300.390.400.200.215', 'B03.353.625.375.500.215', 'B03.510.415.400.200.215'], ['G02.111.570.080.708.800.325.500', 'G05.360.080.708.800.325.500', 'G05.360.340.024.850.069'], ['H01.158.273.180', 'L01.313.124'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.26... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Nonlinear compliance modulates dynamic bronchoconstriction in a multiscale airway model. | The role of breathing and deep inspirations (DI) in modulating airway hyperresponsiveness remains poorly understood. In particular, DIs are potent bronchodilators of constricted airways in nonasthmatic subjects but not in asthmatic subjects. Additionally, length fluctuations (mimicking DIs) have been shown to reduce me... | ['Animals', 'Bronchi', 'Bronchoconstriction', 'Compliance', 'Humans', 'Models, Biological', 'Nonlinear Dynamics'] | 25,517,167 | [['B01.050'], ['A04.411.125'], ['G09.772.705.700.080'], ['G01.374.590.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.599.850', 'H01.548.675']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Manual thromboaspiration and dilation of thrombosed dialysis access: mid-term results of a simple concept. | PURPOSE: To report the feasibility, safety, and effectiveness of manual thromboaspiration as a single means of declotting dialysis access.MATERIALS AND METHODS: Between April 1994 and December 1996, 59 consecutive conduits (43 polytetrafluoroethylene [PTFE] grafts, 16 native fistulas) were declotted with 8-F or 7-F ang... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arm', 'Arteriovenous Shunt, Surgical', 'Catheterization, Peripheral', 'Female', 'Graft Occlusion, Vascular', 'Humans', 'Male', 'Middle Aged', 'Polytetrafluoroethylene', 'Radiography, Interventional', 'Renal Dialysis', 'Suction', 'Thrombosis', 'Vascular Patency'] | 9,314,373 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A01.378.800.075'], ['E04.035.087', 'E04.100.814.868.249'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['C23.550.767.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D05.750.395.616', 'D25.720.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
[The analysis of preliminary spermatological parameters in potential donors of semen]. | OBJECTIVE: To contribute to the contemporary discussion on the male factor infertility through the evaluation of the basic spermatological parameters in men recruiting for semen donation.DESIGN: A retrospective demographic study.SETTING: Dept. of Obstetrics and Gynaecology, Dept. of Biology, Faculty of Medicine, Palack... | ['Adolescent', 'Adult', 'Humans', 'Male', 'Sperm Count', 'Sperm Motility', 'Spermatozoa', 'Tissue Donors'] | 15,918,262 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.870', 'E01.370.225.992.624', 'E05.200.500.195.870', 'E05.200.992.624', 'E05.242.195.870', 'G04.140.870'], ['E01.370.225.992.812', 'E05.200.992.812', 'G04.198.750'], ['A05.360.490.890', 'A11.497.760'], ['M01.898']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The development of the endotheliochorial mink placenta: light microscopy and scanning electron microscopical morphometry of maternal vascular casts. | The development of the mink endotheliochorial placenta has been studied by means of light microscopy and scanning electron microscopy of maternal vascular corrosion casts. The placental blood vessels of three groups of mink, representing early, intermediate and near-term gestational ages were either perfusion fixed for... | ['Animals', 'Capillaries', 'Chorionic Villi', 'Corrosion Casting', 'Decidua', 'Endometrium', 'Female', 'Microscopy, Electron, Scanning', 'Mink', 'Placenta', 'Placentation'] | 9,924,936 | [['B01.050'], ['A07.015.461.165'], ['A10.615.284.473.200', 'A16.254.750.473.200', 'A16.710.189'], ['E01.370.225.500.620.620.150', 'E01.370.225.750.600.620.150', 'E05.200.500.620.620.150', 'E05.200.750.600.620.150'], ['A05.360.319.679.490.373', 'A16.710.289'], ['A05.360.319.679.490'], ['E01.370.350.515.402.541', 'E05.59... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Jejunal Perforation From Blunt Abdominal Trauma by an End Zone Pylon in a Division I Football Player. | This case highlights the importance of vigilant clinical suspicion in diagnosing abdominal perforation. Intra-abdominal injury can be difficult to identify during competition, and timely diagnosis of jejunal perforation is difficult because of initially subtle clinical findings that gradually progress over time. Identi... | ['Abdominal Injuries', 'Football', 'Humans', 'Intestinal Perforation', 'Jejunum', 'Male', 'Wounds, Nonpenetrating', 'Young Adult'] | 30,130,166 | [['C26.017'], ['I03.450.642.845.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557'], ['A03.556.124.684.500', 'A03.556.249.750'], ['C26.974'], ['M01.060.116.815']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Impact of MDT on incidence rates of leprosy among household contacts. Part 1. Baseline data. | This preliminary study from Gudiyatham Taluk, the leprosy control area of the Schieffelin Leprosy Research & Training Centre, investigated the incidence rates of leprosy among household contacts during the period 1970-1985. The incidence rates of leprosy among the household contacts prior to and during the initiation o... | ['Age Factors', 'Drug Therapy, Combination', 'Family', 'Female', 'Humans', 'India', 'Leprostatic Agents', 'Leprosy', 'Male'] | 2,778,370 | [['N05.715.350.075', 'N06.850.490.250'], ['E02.319.310'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['D27.505.954.122.085.777'], ['C01.150.252.410.040.552.475.371']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Detection of viral DNA in neonatal herpes simplex virus infections: frequent and prolonged presence in serum and cerebrospinal fluid. | Polymerase chain reaction (PCR) assay was used to detect herpes simplex virus (HSV) DNA in mouth, skin, sera, or cerebrospinal fluid (CSF) from seven neonates with HSV infection. In a culture-negative patient, the diagnosis was confirmed by detection of HSV DNA. Serial examinations revealed that HSV DNA remained in the... | ['Base Sequence', 'Blotting, Southern', 'Child', 'Child, Preschool', 'DNA Probes', 'DNA, Viral', 'Encephalitis', 'Herpes Simplex', 'Humans', 'Infant', 'Infant, Newborn', 'Molecular Sequence Data', 'Mouth', 'Nucleic Acid Hybridization', 'Oligonucleotides', 'Polymerase Chain Reaction', 'Predictive Value of Tests', 'Simpl... | 1,649,876 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['M01.060.406'], ['M01.060.406.448'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D13.444.308.568'], ['C10.228.140.430'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.80... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Transplacental pharmacokinetics and teratogenicity of a single dose of retinol (vitamin A) during organogenesis in the mouse. | Pregnant mice received 10 or 100 mg retinol/kg body wt. by gavage on day 11 of gestation (plug day = day 0). One group of animals was used for a pharmacokinetic study. At various times after dosing, plasma and tissue samples were collected and analyzed by HPLC for retinyl esters, retinol, 13-cis- and all-trans-retinoic... | ['Abnormalities, Drug-Induced', 'Animals', 'Chromatography, High Pressure Liquid', 'Diterpenes', 'Dose-Response Relationship, Drug', 'Female', 'Fetus', 'Isomerism', 'Maternal-Fetal Exchange', 'Mice', 'Placenta', 'Pregnancy', 'Retinyl Esters', 'Tissue Distribution', 'Vitamin A', 'Yolk Sac'] | 2,772,923 | [['C16.131.042'], ['B01.050'], ['E05.196.181.400.300'], ['D02.455.849.291'], ['G07.690.773.875', 'G07.690.936.500'], ['A16.378'], ['G02.111.570.685', 'G02.607.445'], ['G08.686.784.769.455'], ['B01.050.150.900.649.313.992.635.505.500'], ['A16.710'], ['G08.686.784.769'], ['D02.241.400.500', 'D02.455.326.271.665.202.495.7... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental impacts of genetically modified (GM) crop use 1996-2013: Impacts on pesticide use and carbon emissions. | This paper updates previous assessments of how crop biotechnology has changed the environmental impact of global agriculture. It focuses on the environmental impacts associated with changes in pesticide use and greenhouse gas emissions arising from the use of GM crops since their first widespread commercial use in the ... | ['Carbon Footprint', 'Crops, Agricultural', 'Environmental Monitoring', 'Global Warming', 'Greenhouse Effect', 'Insecticides', 'Pest Control, Biological', 'Pesticides', 'Plants, Genetically Modified'] | 25,760,405 | [['G16.500.275.066', 'N06.230.063'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.175.374.500'], ['G16.500.175.827', 'N06.230.265'], ['D27.720.031.700.491', 'D27.888.723.491'], ['N06.850.780.200.650.650'], ['D27.720.031.700', 'D27.888.723'], ['B01.650.520', 'B... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Testosterone destroys the transcortin-receptor complex. | Dissociation of the complex of transcortin receptor with immobilized transcortin in the presence of 10(-5) M testosterone has been shown with the use of affinity chromatography on transcortin-Sepharose. The specificity of this effect is confirmed by its abrogation in the presence of cortisol. The testosterone effect ha... | ['Cell Membrane', 'Chromatography, Affinity', 'Decidua', 'Electrophoresis, Polyacrylamide Gel', 'Endometrium', 'Female', 'Humans', 'Isoelectric Focusing', 'Molecular Weight', 'Pregnancy', 'Receptors, Cell Surface', 'Serpins', 'Testosterone', 'Transcortin'] | 1,314,597 | [['A11.284.149'], ['E05.196.181.400.170'], ['A05.360.319.679.490.373', 'A16.710.289'], ['E05.196.401.402', 'E05.301.300.319'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.401.663', 'E05.301.300.663'], ['G02.494'], ['G08.686.784.769'], ['D12.776.543.750'], ['D12.644.861', 'D12.776... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes. | BACKGROUND AND PURPOSE: Glutamate transporters play a major role in maintaining brain homeostasis and the astrocytic transporters, EAAT1 and EAAT2, are functionally dominant. Astrocytic excitatory amino acid transporters (EAATs) play important roles in various neuropathologies wherein astrocytes undergo cytoskeletal ch... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'Actins', 'Animals', 'Aspartic Acid', 'Astrocytes', 'Biological Transport', 'Cells, Cultured', 'Excitatory Amino Acid Transporter 1', 'Excitatory Amino Acid Transporter 2', 'Glial Fibrillary Acidic Protein', 'Glutamic Acid', 'Mice', 'Mice, Inbred C57BL', 'Nerve Tissue P... | 21,309,758 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['A08.637.200', 'A11.650.200'], ['G03.143'], ['A11.251'], ['D12.776.157.530.200.249.500.500.500', 'D12.776.15... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors. | BACKGROUND: Morphine and its derivatives are key drugs in pain control. Despite its well-known analgesic properties morphine at high concentrations may be proalgesic. Particularly, short-lasting painful sensations have been reported upon dermal application of morphine. To study a possible involvement of TRP receptors i... | ['Acrolein', 'Animals', 'Bradykinin', 'Calcitonin Gene-Related Peptide', 'Calcium Signaling', 'Capsaicin', 'Dose-Response Relationship, Drug', 'Extremities', 'Ganglia, Spinal', 'Hot Temperature', 'Humans', 'Ion Channel Gating', 'Mice', 'Morphine', 'Naloxone', 'Neurons', 'Skin', 'TRPA1 Cation Channel', 'TRPV Cation Chan... | 19,371,406 | [['D02.047.122'], ['B01.050'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['D12.644.400.097', 'D12.776.631.650.097'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D02.065.690.500', 'D02.455.32... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Methods of youth suicide in New Zealand: trends and implications for prevention. | OBJECTIVE: One commonly suggested approach to reducing suicide is to restrict access to potentially lethal means of suicide. This paper summarises recent trends in methods of suicide among young people in New Zealand and examines the feasibility of suicide prevention through restricting access to methods of suicide.MET... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Incidence', 'Male', 'New Zealand', 'Suicide'] | 10,881,965 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.639.760.747', 'Z01.678.100.747'], ['F01.145.126.980.875', 'I01.880.735.856']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Microbial pathogens associated with acute childhood diarrhoea in Kumasi, Ghana. | BACKGROUND: Diarrhoeal diseases are among the most frequent causes of morbidity and mortality in children worldwide, especially in sub-Saharan Africa. This case-control study was conducted to investigate the bacterial, viral and parasitic pathogens associated with acute diarrhoea among children attending three health f... | ['Acute Disease', 'Bacterial Infections', 'Case-Control Studies', 'Child, Preschool', 'Diarrhea', 'Feces', 'Female', 'Ghana', 'Humans', 'Infant', 'Malaria', 'Male', 'Rotavirus Infections'] | 28,693,616 | [['C23.550.291.125'], ['C01.150.252'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['C23.888.821.214'], ['A12.459'], ['Z01.058.290.190.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.610.752.530', 'C01.920.875'], ['C01.925.782.791.81... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Influence of everolimus on cyclosporine Neoral pharmacokinetics in Chinese de novo cardiac transplant recipients. | OBJECTIVE: This study sought to determine the influence of everolimus on cyclosporine Neoral (CsA) pharmacokinetics over the first 6 months after heart transplantation in Chinese recipients.METHODS: Six de novo cardiac recipients receiving a CsA-everolimus-based immunosuppressive regimen after rabbit antithymoglobulin ... | ['Adult', 'Azathioprine', 'China', 'Cyclosporine', 'Drug Therapy, Combination', 'Everolimus', 'Female', 'Heart Transplantation', 'Humans', 'Immunosuppressive Agents', 'Male', 'Middle Aged', 'Sirolimus'] | 16,979,990 | [['M01.060.116'], ['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['Z01.252.474.164'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['E02.319.310'], ['D02.540.505.760.500'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.47... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Structural features of paramyxovirus F protein required for fusion initiation. | On the basis of the coordinates of the related Newcastle disease virus (NDV) F protein, Valine-94, a determinant of measles virus (MV) cytopathicity, is predicted to lie in a cylindrical cavity with 10 A diameter located at the F neck. A 16-residue domain around V94 is functionally interchangeable between NDV and MV F,... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Biological Transport', 'Cell Fusion', 'Chlorocebus aethiops', 'HeLa Cells', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Measles virus', 'Membrane Proteins', 'Models, Molecular', 'Protein Conformation', 'Respirovirus', 'Sequence Homology, Amino Ac... | 12,779,319 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['G03.143'], ['E05.242.307', 'G04.155'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mitigation of Ventilator-induced Diaphragm Atrophy by Transvenous Phrenic Nerve Stimulation. | RATIONALE: Ventilator-induced diaphragm dysfunction is a significant contributor to weaning difficulty in ventilated critically ill patients. It has been hypothesized that electrically pacing the diaphragm during mechanical ventilation could reduce diaphragm dysfunction.OBJECTIVES: We tested a novel, central line cathe... | ['Animals', 'Catheterization, Central Venous', 'Diaphragm', 'Disease Models, Animal', 'Electric Stimulation Therapy', 'Muscular Atrophy', 'Phrenic Nerve', 'Respiration, Artificial', 'Swine'] | 27,500,981 | [['B01.050'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['A02.633.567.900.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['C10.597.613.612', 'C23.300.070.500', 'C23.888.592.608.612'], ['A08.800.800.720.150.700'], ['E02.041.625', 'E02.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transient Anosmia Induces Depressive-like and Anxiolytic-like Behavior and Reduces Amygdalar Corticotropin-Releasing Hormone in a ZnSO4-Induced Mouse Model. | Olfactory loss is known to affect both mood and quality of life. Transient anosmia was induced in mice to study the resulting changes in mood, behavior, and on a molecular level. Transient anosmia was induced by a single intranasal instillation of ZnSO4 in BALB/c mice. Hematoxylin and eosin (HE) staining, and potato ch... | ['Administration, Intranasal', 'Amygdala', 'Animals', 'Anxiety', 'Behavior, Animal', 'Corticotropin-Releasing Hormone', 'Depression', 'Disease Models, Animal', 'Hypothalamus', 'Male', 'Maze Learning', 'Mice', 'Mice, Inbred BALB C', 'Olfaction Disorders', 'Olfactory Mucosa', 'Receptors, Glucocorticoid', 'Zinc Sulfate'] | 29,438,489 | [['E02.319.267.120.655.500'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['F01.470.132'], ['F01.145.113'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['F01.145.126.350'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two new species of freshwater crabs of the genus Sundathelphusa Bott, 1969 (Decapoda: Brachyura: Gecarcinucidae) from caves in Luzon, Philippines. | Two cave species of Sundathelphusa are described from a karst area in southern Luzon, Philippines. Both species have elongated ambulatory legs but the eyes and carapace pigmentation are well developed, indicating they are not troglobites. Sundathelphusa danae sp. nov. is superficially more similar to S. longipes (Balss... | ['Animal Distribution', 'Animal Structures', 'Animals', 'Brachyura', 'Caves', 'Female', 'Male', 'Philippines'] | 24,943,634 | [['F01.145.113.069', 'G16.049'], ['A13'], ['B01.050'], ['B01.050.500.131.365.190.110'], ['G01.311.169', 'G16.500.275.067', 'N06.230.066'], ['Z01.252.145.671', 'Z01.639.790']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Synthesis and molecular structure of new acyclic analogues of nucleotides with a 1,2-alkadienic skeleton. | Reaction of 1-chloro-4-(diethoxyphosphonyl)alka-2,3-dienes 14,15 with purine and pyrimidine heterocyclic bases in the presence of cesium carbonate afforded new acyclic analogues of nucleotides containing a 1,2-alkadienic skeleton 18-23. Dealkylation of 18-23 furnished phosphonic acids 2a-f. In contrast, alkylation reac... | ['Alkadienes', 'Crystallography, X-Ray', 'Models, Molecular', 'Molecular Conformation', 'Molecular Structure', 'Nucleotides'] | 14,685,323 | [['D02.455.326.271.665.146'], ['E05.196.309.742.225'], ['E05.599.595'], ['G02.111.570.820'], ['G02.111.570', 'G02.466'], ['D09.408.620', 'D13.695']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The forensic implications of Turner's syndrome. | Turner's syndrome, the most common sex chromosome disorder of females, is caused by complete or partial loss of one X chromosome and is associated with a wide range of internal and external manifestations and increased mortality rates (three to nine times the background population). While individuals with Turner's synd... | ['Adult', 'Aorta', 'Cardiac Tamponade', 'Death, Sudden, Cardiac', 'Epilepsy', 'Female', 'Forensic Pathology', 'Humans', 'Middle Aged', 'Ovarian Neoplasms', 'Pericardial Effusion', 'Teratoma', 'Turner Syndrome', 'Young Adult'] | 24,313,855 | [['M01.060.116'], ['A07.015.114.056'], ['C14.280.155'], ['C14.280.383.220', 'C23.550.260.322.250'], ['C10.228.140.490'], ['H02.403.330.300', 'H02.403.650.249', 'I01.198.780.937.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.68... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Resistance to falciparum malaria among adults in central Sudan. | Adults claiming resistance to malaria were identified in the Sennar region of central Sudan, where P. falciparum is hyperendemic but seasonal in transmission. Indirect fluorescent antibody (IFA) titers of sera from these individuals were comparable to those of malaria patients with positive blood films, indicating equa... | ['Adolescent', 'Adult', 'Age Factors', 'Blood Group Antigens', 'Child', 'Erythrocytes', 'Gene Frequency', 'Glucosephosphate Dehydrogenase', 'Haptoglobins', 'Hemoglobin A', 'Hemoglobin, Sickle', 'Heterozygote', 'Humans', 'Malaria', 'Phosphoglucomutase', 'Phosphogluconate Dehydrogenase', 'Plasmodium falciparum', 'Polymor... | 2,936,261 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D23.050.301.290', 'D23.050.705.230'], ['M01.060.406'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G05.330'], ['D08.811.682.047.150.300'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Gastrobronchial fistula]. | A-79-year old man, treated by thoracic fundoplication for hiatus hernia with symptomatic gastroesophageal reflux, 12 years previously, was examined for persistent cough and left basal pneumonia. Esophagogastroscopy revealed a gastrobronchial fistule which was confirmed by endoscopical fistulograms. Surgical treatment l... | ['Aged', 'Bronchial Fistula', 'Endoscopy', 'Gastric Fistula', 'Humans', 'Male', 'Radiography'] | 1,478,410 | [['M01.060.116.100'], ['C08.127.196', 'C08.702.196', 'C23.300.575.687.225'], ['E01.370.388.250', 'E04.502.250'], ['C06.267.375', 'C23.300.575.185.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Accuracy of dental age estimation charts: Schour and Massler, Ubelaker and the London Atlas. | Dental age estimation charts are frequently used to assess maturity and estimate age. The aim of this study was to assess the accuracy of estimating age of three dental development charts (Schour and Massler, Ubelaker, and the London Atlas). The test sample was skeletal remains and dental radiographs of known-age indiv... | ['Adolescent', 'Adult', 'Age Determination by Teeth', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'London', 'Male', 'Reference Values', 'Tooth', 'Young Adult'] | 24,470,177 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.700.720.050', 'E01.370.600.024.650.500', 'E05.041.650.500', 'E06.342.764.142', 'E06.623.500'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['Z01.433.553', 'Z01.542.363.300.553'], ['E05.978.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Prevalence of traumatic dural venous sinus thrombosis in high-risk acute blunt head trauma patients evaluated with multidetector CT venography. | PURPOSE: To determine the prevalence of trauma-related dural venous sinus thrombosis (DVST) in high-risk patients with blunt head trauma who are examined with multidetector computed tomographic (CT) venography.MATERIALS AND METHODS: With institutional review board approval, HIPAA compliance, and waived informed consent... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Female', 'Head Injuries, Closed', 'Humans', 'Infant', 'Jugular Veins', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Phlebography', 'Prevalence', 'Retrospective Studies', 'Sinus Thrombosis, Intracranial... | 20,413,766 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['C10.900.300.350', 'C26.915.300.450', 'C26.974.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reducing injury rates using a community-based approach. | BACKGROUND: Injuries are the number one cause of morbidity and mortality to persons aged 1-44 years in the United States. Community-based interventions offer one approach to reducing injuries.OBJECTIVE: To determine whether injuries could be reduced over a 5 year period by at least 20% in a midwestern community using a... | ['Accident Prevention', 'Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Community Participation', 'Humans', 'Infant', 'Ohio', 'United States', 'Wounds and Injuries'] | 17,823,588 | [['N06.850.135.060'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['N02.421.143.212', 'N03.540.245.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.107.567.875.075.512', 'Z01.107.567.875.350.540', 'Z01.107.567.875.510.540'], ['Z01.107.567.875'], ['C26']] | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Corneal Ulcer Leading to Evisceration or Enucleation in a Tertiary Eye Care Center in Thailand: Clinical and Microbiological Characteristics. | BACKGROUND: Very severe corneal infection can lead to permanent visual loss, and there is still inadequate knowledge about these severe cases.OBJECTIVE: To identify clinical and microbiological characteristics of corneal ulcers resulting in evisceration or enucleation in a tertiary eye care center in Thailand.MATERIAL ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Corneal Ulcer', 'Eye Enucleation', 'Eye Evisceration', 'Eye Infections, Bacterial', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pseudomonas aeruginosa', 'Retrospective Studies', 'Tertiary Care Centers', 'Visual Acuity'] | 27,266,225 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.375.177', 'C11.204.564.225', 'C11.294.177'], ['E04.540.429'], ['E04.540.431'], ['C01.150.252.289', 'C01.375.354', 'C11.294.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Routine immunohistochemical characterization of short term in vitro explants from human intracranial tumours. | 35 intracranial tumours, 18 gliomas, 12 meningiomas, one neurilemmoma (neurinoma), one malignant melanoma and two metastases were successfully grown in-vitro and were submitted to immunocytochemical reactions, including cytokeratin, glial fibrillary acid protein (GFAP), vimentin, fibronectin, S-100 protein, neurofilame... | ['Biomarkers, Tumor', 'Brain Neoplasms', 'Fibronectins', 'Glial Fibrillary Acidic Protein', 'Glioma', 'Humans', 'Immunohistochemistry', 'Intermediate Filament Proteins', 'Melanoma', 'Meningioma', 'Myelin Basic Protein', 'Neurilemmoma', 'Phosphopyruvate Hydratase', 'S100 Proteins', 'Vimentin'] | 1,708,642 | [['D23.101.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Decompressive craniectomy with lattice duraplasty. | A method of opening dura for decompressive craniectomies is described. Numerous cuts intersecting in a lattice pattern allow the dura to expand in a gradual and controlled manner minimising the chances of cortical laceration or venous kinking on the craniectomy edge. | ['Adult', 'Brain Edema', 'Craniotomy', 'Decompression, Surgical', 'Dura Mater', 'Head Injuries, Closed', 'Hematoma, Subdural, Acute', 'Humans', 'Intracranial Hypertension', 'Male', 'Tomography, X-Ray Computed'] | 14,963,748 | [['M01.060.116'], ['C10.228.140.187'], ['E04.525.190'], ['E04.188'], ['A08.186.566.395'], ['C10.900.300.350', 'C26.915.300.450', 'C26.974.382'], ['C10.228.140.300.535.450.400.050', 'C10.900.300.837.600.050', 'C14.907.253.573.400.450.050', 'C23.550.414.838.700.100', 'C23.550.414.913.700.100', 'C26.915.300.490.450.050'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Analysis of pregnant women's narratives]. | Due to the fact that numerous social situations are directed by the provision of medical care and guide individuals to conform to general norms which are to the detriment of the individuality of specific cases, care remains embedded in logic intrinsically linked to machines and reflecting these norms, and finally elimi... | ['Adult', 'Data Collection', 'Delivery of Health Care', 'Female', 'Health Surveys', 'Humanism', 'Humans', 'Pregnancy', 'Public Health', 'Social Welfare'] | 15,185,589 | [['M01.060.116'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N04.590.374', 'N05.300'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['K01.752.566.479.174', 'N05.350.835'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['H02.403.720',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Two domains for splicing in the intron of the phage T4 thymidylate synthase (td) gene established by nondirected mutagenesis. | Of 97 nondirected T4 thymidylate synthase-defective (td) mutations, 27 were mapped to the intron of the split td gene. Clustering of these intron mutations defined two domains that are functional in splicing, each within approximately 220 residues of the respective splice sites. Two selected mutations, tdN57 and tdN47,... | ['Base Sequence', 'Chromosome Mapping', 'Genes, Viral', 'Introns', 'Mutation', 'Nucleic Acid Conformation', 'Nucleic Acid Hybridization', 'RNA Splicing', 'T-Phages', 'Thymidylate Synthase'] | 3,791,415 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['G05.365.590'], ['G02.111.570.820.486', 'G05.360.580'], ['E05.393.661', 'G02.111.611'], ['G02.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Growth and physiological responses to successional water deficit and recovery in four warm-temperate woody species. | Plant responses to drought and their subsequent rehydration can provide evidence for forest dynamics within the context of climate change. In this study, the seedlings of two native species (Vitex negundo var. heterophylla, Quercus acutissima) and two exotic species (Robinia pseudoacacia, Amorpha fruticosa) to China we... | ['China', 'Dehydration', 'Droughts', 'Fabaceae', 'Introduced Species', 'Quercus', 'Robinia', 'Trees', 'Vitex', 'Water'] | 30,637,759 | [['Z01.252.474.164'], ['C18.452.950.179', 'C23.550.274'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['B01.650.940.800.575.912.250.401'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['B01.650.940.800.575.912.250.859.750.300.500'], ['B01.650.940.800.575.912.250.401.716'... | ['Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Accreditation and nursing practice. | As part of a larger study (Conway, 1993) the literature relating to accreditation of prior learning (APL), accreditation of prior experiential learning (APEL), and the credit accumulation and transfer scheme (CATS) was examined. Significant influencing factors are identified and a general overview of the background to ... | ['Accreditation', 'Education, Nursing', 'Educational Measurement', 'Humans'] | 8,241,734 | [['N03.706.110.070', 'N05.700.200.100'], ['I02.358.462'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Structural and spectral characterisation of the antenna complexes of Rhodocyclus gelatinosus. Indications of a hairpin-like-arranged antenna apoprotein with an unusually high alanine content. | The core antenna/reaction-centre complex RC-B875 and the peripheral antenna complex B800-850 of the two strains DSM 149 and DSM 151 of the purple non-sulphur bacterium Rhodocyclus gelatinosus have been isolated from photosynthetic membranes by means of lauryl-N,N-dimethyl-amineoxide as a detergent and subsequent sucros... | ['Alanine', 'Amino Acid Sequence', 'Apoproteins', 'Bacterial Proteins', 'Centrifugation, Density Gradient', 'Chromatography, High Pressure Liquid', 'Detergents', 'Light-Harvesting Protein Complexes', 'Mass Spectrometry', 'Molecular Sequence Data', 'Protein Conformation', 'Protein Structure, Secondary', 'Rhodospirillale... | 8,020,505 | [['D12.125.042'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.070'], ['D12.776.097'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.196.181.400.300'], ['D27.720.877.265', 'J01.516.381'], ['D05.500.562.488.490', 'D08.811.600.710.490', 'D12.776.543.930.500.490', 'D12.776.765.199.750.750.490'], ['E05.196.566'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
The incidence of nosocomial toxigenic clostridium difficile associated diarrhea in Tehran tertiary medical centers. | Clostridium difficile is the most common cause of nosocomial diarrhea. It is usually a consequence of antibiotic treatment, But sporadic cases can occur. This study was aimed to determine the frequency of the nosocomial Clostridium difficile (C. difficile) associated diarrhea in Tehran University of Medical Sciences ho... | ['Academic Medical Centers', 'Adolescent', 'Adult', 'Aged', 'Anti-Bacterial Agents', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Clostridioides difficile', 'Cross Infection', 'Diarrhea', 'Drug Resistance, Bacterial', 'Enterocolitis, Pseudomembranous', 'Feces', 'Female', 'Humans', 'Incidence', 'Infant', 'In... | 21,287,466 | [['N02.278.020'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['B03.353.625.657.500'], ['C01.248', 'C23.550.291.875.500'], ['C23.888.821.214'], ['G06.09... | ['Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ophthalmic genetics: a genealogical guide to sources in England and Wales. | Large pedigrees are fundamental to seeking new genes; they can be constructed on the basis of a family history but can frequently be enlarged considerably from public records. Genealogical sources in England and Wales consist of public records such as civil registration of births, marriages, and deaths, census returns,... | ['Censuses', 'Endophthalmitis', 'England', 'Genealogy and Heraldry', 'Humans', 'Information Storage and Retrieval', 'Wales', 'Wills'] | 8,825,921 | [['I01.240.205', 'N01.224.175', 'N06.850.505.400.225'], ['C01.375.265', 'C11.294.265'], ['Z01.542.363.300'], ['K01.400.359'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['Z01.542.363.914'], ['I01.880.604.583.927']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
An immunohistochemical study of endocrine cells of the alimentary tract of the King's skink (Egernia kingii). | The gastrointestinal tract of the King's skink (Egernia kingii) was examined for the presence of fifteen regulatory peptides, two proteinases and an amine by immunohistochemical methods. Immunoreactivity was detected for somatostatin, gastrin, motilin, bovine pancreatic polypeptide, pepsinogen and serotonin, but not fo... | ['Animals', 'Chromaffin System', 'Digestive System', 'Esophagus', 'Gastric Mucosa', 'Hormones', 'Immune Sera', 'Immunoenzyme Techniques', 'Intestinal Mucosa', 'Lizards'] | 2,254,171 | [['B01.050'], ['A06.224'], ['A03'], ['A03.556.875.500'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472', 'D27.505.696.399.472'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.47... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine. | 1. Mexiletine is extensively metabolized in man by C- and N-oxidation and the aim of the present study was to characterize major cytochrome P450 enzyme(s) involved in the formation of N-hydroxymexiletine. 2. Incubations with genetically engineered microsomes indicated that the formation rate of N-hydroxymexiletine was ... | ['Anti-Arrhythmia Agents', 'Benzoflavones', 'Cell Line', 'Cytochrome P-450 Enzyme Inhibitors', 'Cytochrome P-450 Enzyme System', 'DNA, Complementary', 'Humans', 'Hydroxylation', 'Kinetics', 'Mexiletine', 'Microsomes, Liver', 'Mitochondria, Liver', 'Mixed Function Oxygenases', 'NADP', 'Oxidation-Reduction', 'Saccharomyc... | 12,519,691 | [['D27.505.954.411.097'], ['D03.383.663.283.266.450.175', 'D03.633.100.150.266.450.175'], ['A11.251.210'], ['D27.505.389.500', 'D27.505.519.389.335'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of myocardial acceleration during isovolumic contraction in evaluating subclinical right ventricular systolic dysfunction in type 2 diabetes mellitus patients. | AIM: In diabetes mellitus (DM) patients, left ventricular dysfunction is widely evaluated and established by conventional diagnostic methods, whereas right ventricular (RV) function is not as sufficiently evaluated. The aim of this study is to assess the preclinical effects of DM on RV function by using novel Tissue Do... | ['Acceleration', 'Diabetes Mellitus, Type 2', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Ultrasonography', 'Ventricular Dysfunction, Right'] | 20,584,066 | [['G01.482.107'], ['C18.452.394.750.149', 'C19.246.300'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.330.580', 'G11.427.494.570'], ['E01.370.350.850'], ['C14.280.945.910']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Beam shaping assembly design of 7 | The development of a medical facility for boron neutron capture therapy at Budker Institute of Nuclear Physics is under way. The neutron source is based on a tandem accelerator with vacuum insulation and lithium target. The proposed accelerator is conceived to deliver a proton beam around 10 mA at 2.3 MeV proton beam. ... | ['Beryllium', 'Boron Neutron Capture Therapy', 'Brain Neoplasms', 'Computer Simulation', 'Equipment Design', 'Glioblastoma', 'Humans', 'Lithium', 'Phantoms, Imaging', 'Radioisotopes', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted'] | 29,890,472 | [['D01.268.552.075', 'D01.268.557.080', 'D01.552.547.080'], ['E02.815.722.500.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['L01.224.160'], ['E05.320'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['B01.050.150.900.649.313.988.400.112.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Identification and characterization of the product release steps within the catalytic cycle of protochlorophyllide oxidoreductase. | The chlorophyll biosynthetic enzyme protochlorophyllide reductase (POR) catalyzes the reduction of protochlorophyllide (Pchlide) into chlorophyllide (Chlide) with reduced nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor. POR is a light-driven enzyme, which has provided a unique opportunity to trap inte... | ['Catalysis', 'Chlorophyllides', 'Cyanobacteria', 'Darkness', 'Escherichia coli', 'Light', 'NADP', 'Oxidoreductases Acting on CH-CH Group Donors', 'Photochemistry', 'Protochlorophyllide', 'Recombinant Proteins', 'Spectrometry, Fluorescence', 'Temperature'] | 15,209,523 | [['G02.130'], ['D03.383.129.578.840.374.180', 'D03.633.400.909.374.180', 'D04.345.783.374.180'], ['B03.280', 'B03.440.475.100'], ['G01.590.540.233'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D03.633.100.759.646.138.749', 'D08... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Lhermitte-Duclos disease associated with Cowden syndrome. | Lhermitte-Duclos disease or dysplastic gangliocytoma of the cerebellum, is a rare cerebellar lesion, which can cause mass effects in the posterior fossa. It may occur sporadically, or in association with Cowden syndrome. Cowden syndrome or multiple hamartoma-neoplasia syndrome, is an uncommon autosomal dominant conditi... | ['Cerebellar Neoplasms', 'Female', 'Ganglioneuroma', 'Hamartoma Syndrome, Multiple', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged'] | 17,485,210 | [['C04.588.614.250.195.411.211', 'C10.228.140.211.500.200', 'C10.228.140.252.200', 'C10.551.240.250.400.300'], ['C04.557.465.625.600.355', 'C04.557.470.670.355', 'C04.557.580.625.600.355'], ['C04.445.435', 'C04.651.435', 'C04.700.435', 'C16.320.700.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.8... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dried blood spots are a useful tool for quality assurance of rapid HIV testing in Kigali, Rwanda. | A study was conducted in two primary health facilities in Kigali, Rwanda, to determine whether dried blood spots (DBS) used for quality control of HIV testing would give comparable results with serum after being stored for a period of 14 days and 30 days at ambient temperature. DBS and serum specimens were collected fr... | ['Adult', 'Blood Specimen Collection', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'HIV Seropositivity', 'HIV-1', 'Humans', 'Male', 'Quality Control', 'RNA, Viral', 'Reagent Kits, Diagnostic', 'Rwanda', 'Sensitivity and Specificity', 'Temperature', 'Time Factors', 'Young Adult'] | 19,249,069 | [['M01.060.116'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Bovine tuberculosis in an Asian small-clawed otter (Aonyx cinerea) in the Republic of Korea. | Bovine tuberculosis caused by Mycobacterium bovis has a wide range of hosts including cattle and humans, but its incidence in otters is very rare. Our report describes a case of bovine tuberculosis in an Asian small-clawed otter (Aonyx cinerea). A deceased female otter ~2-3 years of age that was raised in an aquarium w... | ['Animals', 'Cattle', 'Diagnosis, Differential', 'Female', 'Mycobacterium bovis', 'Otters', 'Republic of Korea', 'Tuberculosis, Bovine'] | 26,289,719 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E01.171'], ['B03.510.024.962.500.402', 'B03.510.460.400.410.552.552.402'], ['B01.050.150.900.649.313.750.250.575.600'], ['Z01.252.474.557.750'], ['C01.150.252.410.040.552.846.538', 'C22.196.927']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[Feto-maternal transfusion. Description of a case]. | Feto-maternal transfusion is an uncommon cause of neonatal anemia due to the passage of fetal blood in maternal circulation, in an amount greater than 150-180 ml. The onset of anemia may be acute or chronic in relation to the speed of blood loss. The case that we report has intermediate features between the acute and c... | ['Acute Disease', 'Chronic Disease', 'Female', 'Fetomaternal Transfusion', 'Humans', 'Infant, Newborn', 'Male', 'Pregnancy'] | 8,145,688 | [['C23.550.291.125'], ['C23.550.291.500'], ['C15.378.071.363.511', 'C16.614.053.511'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of 1,25(OH)2D3 on its receptor mRNA levels and osteocalcin synthesis in human osteosarcoma cells. | Hormone-dependent accumulation of specific binding sites for 1,25(OH)2D3 and changes in human 1,25-dihydroxy-vitamin D receptor (hVDR) mRNA levels were examined in cell lines (MG-63, SaOs-2 and U2-Os) derived from human bone. Osteocalcin synthesis and secretion as well as alkaline phosphatase activity were also charact... | ['Alkaline Phosphatase', 'Base Sequence', 'Calcitriol', 'Humans', 'Molecular Sequence Data', 'Nucleic Acid Hybridization', 'Osteocalcin', 'Osteosarcoma', 'RNA, Messenger', 'RNA, Neoplasm', 'Receptors, Calcitriol', 'Receptors, Steroid', 'Tumor Cells, Cultured'] | 2,153,413 | [['D08.811.277.352.650.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['E05.393.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Stillbirth during infection with Middle East respiratory syndrome coronavirus. | We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan. A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positiv... | ['Adolescent', 'Adult', 'Coronavirus', 'Coronavirus Infections', 'Female', 'Humans', 'Jordan', 'Pregnancy', 'Respiratory Tract Infections', 'Retrospective Studies', 'Stillbirth', 'Young Adult'] | 24,474,813 | [['M01.060.057'], ['M01.060.116'], ['B04.820.578.500.540.150'], ['C01.925.782.600.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.400'], ['G08.686.784.769'], ['C01.748', 'C08.730'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.7... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A new quantitative thermospray LC-MS method for nicotine and its metabolites in biological fluids. | A rapid thermospray liquid chromatography-mass spectrometry (TSP LC-MS) method is described for the simultaneous determination of nicotine and 17 of its metabolites. Chemical ionization of nicotine and its metabolites separated by reversed-phase HPLC is achieved by postcolumn addition of ammonium acetate buffer with th... | ['Chromatography, High Pressure Liquid', 'Cotinine', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Nicotine'] | 2,246,349 | [['E05.196.181.400.300'], ['D03.383.773.812.180'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.760.570', 'D03.383.725.518']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function. | WASH is an Arp2/3 activator of the Wiskott-Aldrich syndrome protein superfamily that functions during endosomal trafficking processes in collaboration with the retromer and sorting nexins, but its in vivo function has not been examined. To elucidate the physiological role of WASH in T cells, we generated a WASH conditi... | ['Animals', 'CD28 Antigens', 'CD4 Antigens', 'Cell Proliferation', 'Cells, Cultured', 'Encephalomyelitis, Autoimmune, Experimental', 'Gene Deletion', 'Glucose Transporter Type 1', 'Glycolysis', 'Interleukin-2', 'Lymphocyte Activation', 'Lymphocyte Function-Associated Antigen-1', 'Mice', 'Mice, Knockout', 'Microfilament... | 23,275,443 | [['B01.050'], ['D12.776.543.750.705.222.500', 'D23.050.301.264.894.128', 'D23.101.100.894.128'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['C10.114.703.300', 'C10.228.140.695.562.250', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early career choice: an unsuccessful program. | During the 1960s, early educational specialization and increasingly elective curricula were promoted as instructional advances. More recently, early educational specialization has been suggested as a solution to high educational costs and knowledge overload. In 1973 the McGill University Faculty of Medicine introduced ... | ['Achievement', 'Attitude of Health Personnel', 'Career Choice', 'Clinical Clerkship', 'Curriculum', 'Education, Medical, Undergraduate', 'Educational Measurement', 'Humans', 'Medicine', 'Quebec', 'Specialization', 'Students, Medical', 'Surveys and Questionnaires', 'Time Factors'] | 6,887,213 | [['F01.658.059', 'F02.784.629.054'], ['F01.100.050', 'N05.300.100'], ['F02.463.785.373.346.400'], ['I02.358.105'], ['I02.158'], ['I02.358.399.450'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['Z01.107.567.176.791'], ['H02.811'], ['M01.848.769.602'], ['E05.318.308.980', 'N05.715.360.300.... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Assessing local progression after stereotactic body radiation therapy for unresectable pancreatic adenocarcinoma: CT versus PET. | PURPOSE: Evaluation of local tumor progression (LP) has typically been defined by contrast-enhanced computed tomography (CT) imaging after stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (PDAC). The purpose of this study is to determine the benefit of adding 18F-fluorodeoxyglucose-posi... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Pancreatic Ductal', 'Disease Progression', 'Female', 'Fluorodeoxyglucose F18', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Positron-Emission Tomography', 'Radiopharmaceuticals', 'Radiosurgery', 'Retrospective Studies', 'Tomography, X-... | 28,274,396 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.625', 'C19.344.421.750'], ['C23.550.291.656'], ['D09.254.229.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.75... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Self-rated health, chronic diseases, and symptoms among middle-aged and elderly men and women. | The objective was to study the association between chronic diseases, symptoms, and poor self-rated health among men and women and in different age groups, and to assess the contribution of chronic diseases and symptoms to the burden of poor self-rated health in the general population. Self-rated health and self-reporte... | ['Adult', 'Age Distribution', 'Aged', 'Chronic Disease', 'Female', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Odds Ratio', 'Risk', 'Sex Distribution', 'Surveys and Questionnaires', 'Sweden'] | 11,927,204 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['C23.550.291.500'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.8... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Volvulus of the small bowel. | Over two years in a major hospital in northern Uganda 12 cases of primary volvulus of the small bowel were seen out of a total of 65 cases of intestinal obstruction which did not include external hernias. This relatively high incidence was associated with drinking large amounts of local "kongo" beer. General systemic s... | ['Adolescent', 'Adult', 'Beer', 'Female', 'Humans', 'Intestinal Obstruction', 'Intestine, Small', 'Male', 'Middle Aged', 'Serotonin', 'Uganda'] | 1,268,549 | [['M01.060.057'], ['M01.060.116'], ['G07.203.100.100.200', 'G07.203.200.250', 'J02.200.100.200', 'J02.350.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['A03.556.124.684'], ['M01.060.116.630'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.050.650'], ['Z01.058.290.120.88... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 |
Clonidine premedication decreases hemodynamic responses to pin head-holder application during craniotomy. | UNLABELLED: The aim of this study was to compare hemodynamic responses to intubation and pin head-holder application in two groups of neurosurgical patients given oral clonidine (3 microg/kg) or oral temazepam (10-20 mg) 90 min before the induction of anesthesia. Fifty patients undergoing elective craniotomy were rando... | ['Adult', 'Anti-Anxiety Agents', 'Clonidine', 'Craniotomy', 'Double-Blind Method', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Preanesthetic Medication', 'Prospective Studies', 'Temazepam'] | 9,585,285 | [['M01.060.116'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D03.383.129.308.436.500'], ['E04.525.190'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of practical techniques to develop latent fingermarks on fired and unfired cartridge cases. | We have tested some widely used and practical fingermark enhancement techniques such as powdering (regular powder dusting and magnetic powder application), cyanoacrylate fuming, fluorescent dying (basic yellow 40), gun blueing solutions and acidified hydrogen peroxide solutions. The results were evaluated and compared ... | ['Copper', 'Cyanoacrylates', 'Dermatoglyphics', 'Firearms', 'Fluorescent Dyes', 'Humans', 'Hydrogen Peroxide', 'Microscopy, Electron, Scanning', 'Powders', 'Solvents', 'Temperature', 'Volatilization', 'Zinc'] | 25,769,130 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.241.081.069.366', 'D02.626.290', 'D05.750.259', 'D25.720.259', 'D25.919.367', 'J01.637.051.720.259', 'J01.637.051.919.367'], ['E05.318.740.225.500.375', 'I01.198.780.937.343', 'N04.452.910.099.500'], ['J01.637.870.350'], ['D27.720.233.348', 'D27.720.470.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Optimization of dual-wavelength intravascular photoacoustic imaging of atherosclerotic plaques using Monte Carlo optical modeling. | Coronary heart disease (the presence of coronary atherosclerotic plaques) is a significant health problem in the industrialized world. A clinical method to accurately visualize and characterize atherosclerotic plaques is needed. Intravascular photoacoustic (IVPA) imaging is being developed to fill this role, but questi... | ['Atherosclerosis', 'Humans', 'Monte Carlo Method', 'Photoacoustic Techniques', 'Plaque, Atherosclerotic', 'Spectrum Analysis'] | 29,076,309 | [['C14.907.137.126.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['E01.370.565', 'E05.696'], ['C23.300.823'], ['E05.196.867']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Anography: a technique for determining the location of the internal opening in perianal fistula. | AIM: Anography is a radiological investigation for fistula-in-ano that identifies the primary fistula track through the internal opening. The efficacy of anography as a radiological method of identifying the location of the internal opening was investigated.METHOD: A retrospective study of 50 patients with a clinical d... | ['Adult', 'Aged', 'Barium', 'Contrast Media', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Rectal Fistula', 'Retrospective Studies', 'Sensitivity and Specificity', 'Young Adult'] | 19,614,670 | [['M01.060.116'], ['M01.060.116.100'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['C06.267.550.600', 'C06.405.469.471.600', 'C06.405.469.860.752', 'C23.300.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide. | Quinoxaline 1,4-dioxide (4) is the historical prototype for modern heterocyclic N-oxide antitumor agents such as 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine, 1) and 3-amino-2-quinoxalinecarbonitrile 1,4-dioxide (11). Early experiments in bacterial cell lines suggested that enzymatic, single-electron reduction... | ['Antibiotics, Antineoplastic', 'DNA', 'DNA Damage', 'Dose-Response Relationship, Drug', 'Electrophoresis, Polyacrylamide Gel', 'Hydrolysis', 'Hypoxia', 'Oxidation-Reduction', 'Plasmids', 'Quinoxalines', 'Xanthine', 'Xanthine Oxidase'] | 11,553,481 | [['D27.505.954.248.106'], ['D13.444.308'], ['G05.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.380'], ['C23.888.852.079'], ['G02.700', 'G03.295.531'], ['G05.360.600'], ['D03.633.100.857'], ['D03.132.960.938', 'D03.633.100.759.758.824.938'], ['D08.811.682.047.928']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioral Consequences of a Bifacial Map in the Mouse Somatosensory Cortex. | The whisker system is an important sensory organ with extensive neural representations in the brain of the mouse. Patterned neural modules (barrelettes) in the ipsilateral principal sensory nucleus of the trigeminal nerve (PrV) correspond to the whiskers. Axons of the PrV barrelette neurons cross the midline and confer... | ['Animals', 'Behavior, Animal', 'Exploratory Behavior', 'Female', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Nerve Net', 'Psychomotor Performance', 'Somatosensory Cortex', 'Touch', 'Vibrissae'] | 28,663,199 | [['B01.050'], ['F01.145.113'], ['F01.145.387', 'F01.658.370'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['A08.511'], ['F02.808', 'G11.427.700', 'G11.561.660'], ... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An outer membrane protein (OmpA) of Escherichia coli can be translocated across the cytoplasmic membrane of Bacillus subtilis. | The translocation of secretory proteins derived from a Gram-positive (Staphylococcus hyicus prolipase) or a Gram-negative (Escherichia coli pre-OmpA protein) bacterium across the cytoplasmic membrane was studied in E. coli and Bacillus subtilis. In both microorganisms, the prolipase was found to be secreted across the ... | ['Amino Acid Sequence', 'Bacillus subtilis', 'Bacterial Outer Membrane Proteins', 'Bacterial Proteins', 'Base Sequence', 'Biological Transport', 'Cell Membrane', 'Escherichia coli', 'Lipase', 'Molecular Sequence Data', 'Protein Precursors', 'Protein Processing, Post-Translational', 'Protein Sorting Signals', 'Recombina... | 8,231,814 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097.120', 'D12.776.543.100'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G03.143'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Immunohistochemical localization of epidermal growth factor receptor and myc oncogene product in human placenta: implication for trophoblast proliferation and differentiation. | Cytologic localization of epidermal growth factor receptor and myc oncogene protein product in developing human placenta was analyzed by avidin/biotin immunoperoxidase techniques with a monoclonal antibody to epidermal growth factor receptor and an affinity purified polyclonal antibody to myc protein product. Epidermal... | ['ErbB Receptors', 'Female', 'Humans', 'Immunologic Techniques', 'Placenta', 'Proto-Oncogene Proteins', 'Trophoblasts'] | 3,548,388 | [['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478'], ['A16.710'], ['D12.776.624.664.700'], ['A11.382.992', 'A16.254.500.766', 'A16.710.802']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beneficial and limiting factors for return to work following anterior cruciate ligament reconstruction: a retrospective cohort study. | PURPOSE: Evidence-based advice for return to work (RTW) after anterior cruciate ligament (ACL) reconstruction is not available. Therefore, the objectives of this study were to determine when patients achieve full RTW, and to explore the beneficial and limiting factors for fully RTW after ACL reconstruction.METHODS: A r... | ['Adult', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Anterior Cruciate Ligament Reconstruction', 'Female', 'Humans', 'Knee Joint', 'Male', 'Retrospective Studies', 'Return to Work', 'Surveys and Questionnaires'] | 27,873,020 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['E04.555.110.026', 'E04.680.101.026'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.5... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Gene expression network analyses in response to air pollution exposures in the trucking industry. | BACKGROUND: Exposure to air pollution, including traffic-related pollutants, has been associated with a variety of adverse health outcomes, including increased cardiopulmonary morbidity and mortality, and increased lung cancer risk.METHODS: To better understand the cellular responses induced by air pollution exposures,... | ['Adult', 'Air Pollutants', 'Air Pollution', 'Carbon', 'Environmental Exposure', 'Gene Expression Profiling', 'Humans', 'Male', 'Microarray Analysis', 'Middle Aged', 'Motor Vehicles', 'Particulate Matter'] | 27,809,917 | [['M01.060.116'], ['D27.888.284.101'], ['N06.850.460.100'], ['D01.268.150'], ['N06.850.460.350'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.588.570'], ['M01.060.116.630'], ['J01.937.500'], ['D20.633']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Cisplatin/vincristine chemotherapy for hypothalamic/visual pathway astrocytomas in young children. | Hypothalamic/visual pathway astrocytomas in children are usually quiescent, but certain cases contain aggressive neoplasms that cause progressive neurological and visual deterioration. Radiotherapy is not recommended in young children because of its adverse effects later in life. This report describes the efficacy of a... | ['Antineoplastic Agents', 'Antineoplastic Agents, Phytogenic', 'Antineoplastic Combined Chemotherapy Protocols', 'Astrocytoma', 'Brain Neoplasms', 'Child, Preschool', 'Cisplatin', 'Female', 'Humans', 'Hypothalamic Neoplasms', 'Infant', 'Magnetic Resonance Imaging', 'Male', 'Vincristine', 'Visual Pathways'] | 9,524,084 | [['D27.505.954.248'], ['D27.505.954.248.179'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406.448'], ['D01.210.375', 'D01.625.125', 'D01.710... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Normal cognitive decline or dementia? | Cognitive speed, inhibitory function, and memory decline with age while crystallised, particularly verbal, abilities remain largely intact. Poor health, fewer years of education, lower activity, the presence of the APOE E4 allele, and high BP appear to predict faster cognitive decline. Dementia is diagnosed in the pres... | ['Aging', 'Cognition', 'Delirium', 'Dementia', 'Depression', 'Diabetes Complications', 'Humans', 'Referral and Consultation', 'Smoking'] | 20,198,932 | [['G07.345.124'], ['F02.463.188'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['C10.228.140.380', 'F03.615.400'], ['F01.145.126.350'], ['C19.246.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.758.849'], ['F01.145.805']] | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Primary hemocyte culture of Penaeus monodon as an in vitro model for white spot syndrome virus titration, viral and immune related gene expression and cytotoxicity assays. | Immortal cell lines have not yet been reported from Penaeus monodon, which delimits the prospects of investigating the associated viral pathogens especially white spot syndrome virus (WSSV). In this context, a method of developing primary hemocyte culture from this crustacean has been standardized by employing modified... | ['Animals', 'Aquaculture', 'Cell Culture Techniques', 'Cells, Cultured', 'Fluorescent Antibody Technique', 'Gene Expression', 'Genes, Viral', 'Hemocytes', 'Models, Biological', 'Penaeidae', 'Reverse Transcriptase Polymerase Chain Reaction', 'Virus Diseases', 'White spot syndrome virus 1'] | 20,807,537 | [['B01.050'], ['J01.040.168'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['G05.297'], ['G05.360.340.024.340.364.875', 'G05.360.340.358... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Solution structure of psi32-modified anticodon stem-loop of Escherichia coli tRNAPhe. | Nucleoside base modifications can alter the structures and dynamics of RNA molecules and are important in tRNAs for maintaining translational fidelity and efficiency. The unmodified anticodon stem-loop from Escherichia coli tRNA(Phe) forms a trinucleotide loop in solution, but Mg2+ and dimethylallyl modification of A37... | ['Anticodon', 'Base Pairing', 'Escherichia coli', 'Models, Molecular', 'Nuclear Magnetic Resonance, Biomolecular', 'Nucleic Acid Conformation', 'Pseudouridine', 'RNA Processing, Post-Transcriptional', 'RNA Stability', 'RNA, Transfer, Phe', 'Solutions'] | 16,377,777 | [['D13.444.735.757.286', 'G05.360.335.060'], ['G02.111.570.820.486.100', 'G02.111.611.500', 'G05.360.580.100'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.599.595'], ['E05.196.867.519.550'], ['G02.111.570.820.486', 'G05.360.580'], ['D03.383.742.680.852.628', 'D13.570.685.852.628', 'D13.570.800.892.62... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimal lineage principle for age-structured populations. | We present a formulation of branching and aging processes that allows age distributions along lineages to be studied within populations, and provides a new interpretation of classical results in the theory of aging. We establish a variational principle for the stable age distribution along lineages. Using this optimal ... | ['Aging', 'Bacteria', 'Biological Evolution', 'Cell Proliferation', 'Models, Biological', 'Population Growth', 'Selection, Genetic'] | 22,220,869 | [['G07.345.124'], ['B03'], ['G05.045', 'G16.075'], ['G04.161.750', 'G07.345.249.410.750'], ['E05.599.395'], ['I01.240.600.660', 'N01.224.625.660', 'N06.850.505.400.700.660'], ['G05.783']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Adults' attitudes to children with epilepsy: the use of a visual analogue scale questionnaire. | A new visual analogue questionnaire was used to compare attitudes to epilepsy in childhood among the parents of three groups of children, one with epilepsy, one with diabetes and one with healthy children. The results showed that there were more similarities than differences between the groups. The parents of the child... | ['Attitude to Health', 'Epilepsy', 'Female', 'Humans', 'Male', 'Parents', 'Surveys and Questionnaires'] | 3,761,231 | [['F01.100.150', 'N05.300.150'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Endothelial-to-mesenchymal transition drives atherosclerosis progression. | The molecular mechanisms responsible for the development and progression of atherosclerotic lesions have not been fully established. Here, we investigated the role played by endothelial-to-mesenchymal transition (EndMT) and its key regulator FGF receptor 1 (FGFR1) in atherosclerosis. In cultured human endothelial cells... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Apolipoproteins E', 'Coronary Artery Disease', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Membrane Proteins', 'Mice', 'Mice, Knockout', 'Receptor, Fibroblast Growth Factor, Type 1', 'Transforming Growth Factor beta'] | 26,517,696 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['B01.050.150.900.649.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fatal hemorrhagic fever caused by West Nile virus in the United States. | BACKGROUND: Most West Nile virus (WNV) infections in humans are asymptomatic; severe disease occurs in relatively few patients and typically manifests as encephalitis, meningitis, or acute flaccid paralysis. A few cases of life-threatening disease with diffuse hemorrhagic manifestations have been reported in Africa; ho... | ['Fatal Outcome', 'Hemorrhagic Fevers, Viral', 'Humans', 'Male', 'Middle Aged', 'Skin', 'United States', 'West Nile Fever'] | 16,652,309 | [['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C01.925.782.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A17.815'], ['Z01.107.567.875'], ['C01.207.245.340.300.887', 'C01.207.399.750.300.887', 'C01.920.500.343.950', 'C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ceramide 1-phosphate enhances calcium entry through voltage-operated calcium channels by a protein kinase C-dependent mechanism in GH4C1 rat pituitary cells. | Sphingomyelin derivatives modulate a multitude of cellular processes, including the regulation of [Ca2+]i (the intracellular free calcium concentration). Previous studies have shown that these metabolites often inhibit calcium entry through VOCCs (voltage-operated calcium channels). In the present study, we show that, ... | ['Animals', 'Calcium', 'Calcium Channels', 'Calcium Signaling', 'Cell Line', 'Ceramides', 'Dose-Response Relationship, Drug', 'Extracellular Space', 'Patch-Clamp Techniques', 'Pituitary Gland', 'Protein Kinase C', 'Rats'] | 15,018,614 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251.210'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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