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An effect of trauma on human cardiovascular control: baroreflex suppression. | Survival from injury depends on the interaction between the patient's own homeostatic responses and treatment given. The function of the principal homeostatic reflex of the cardiovascular system, the arterial baroreflex, was studied in 22 healthy controls and in 21 moderately injured patients (ISS range, 9 to 17; media... | ['Adolescent', 'Adult', 'Blood Pressure', 'Cardiovascular System', 'Electrocardiography', 'Female', 'Heart Rate', 'Humans', 'Injury Severity Score', 'Male', 'Middle Aged', 'Neck', 'Pressoreceptors', 'Suction', 'Wounds and Injuries'] | 2,388,307 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N05.715.360.300.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MULTIPLE CONGENITAL ANOMALIES IN A CHILD WITH 47,XY,+der(8;9)(p10;p10): A CASE REPORT. | Complex small supernumerary marker chromosomes (sSMC) constitute one of the smallest subgroups of sSMC in general. Complex sSMC consist of chromosomal material derived from more than one chromosome. We report a complex sSMC derived from chromosomes 9 and 8, characterized as der(8;9)(p10;p10) resulting from unbalanced t... | ['Abnormalities, Multiple', 'Child, Preschool', 'Chromosomes, Human, Pair 8', 'Chromosomes, Human, Pair 9', 'Dandy-Walker Syndrome', 'Humans', 'Male', 'Trisomy'] | 26,349,185 | [['C16.131.077'], ['M01.060.406.448'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['A11.284.187.520.300.325.345', 'G05.360.162.520.300.325.345'], ['C10.228.140.252.300', 'C10.228.140.602.500', 'C10.500.205', 'C16.131.666.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.210.050.750'... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A weak negative inotropic effect of protamine sulfate upon the isolated canine heart muscle. | The direct effect of protamine sulfate upon myocardial inotropism was studied using an isolated canine heart muscle preparation. Isometric force (F) was decreased to 87.6 +/- 1.2% of control values by a concentration of 50 x 10(-3) g/L protamine, which is approximately equal to the estimated serum concentration of prot... | ['Animals', 'Depression, Chemical', 'Dogs', 'Dose-Response Relationship, Drug', 'Heart', 'In Vitro Techniques', 'Myocardial Contraction', 'Protamines'] | 7,189,330 | [['B01.050'], ['G07.690.773.750'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['A07.541'], ['E05.481'], ['G09.330.580', 'G11.427.494.570'], ['D12.776.660.750', 'D12.776.664.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Encapsulation of ferritin, ribosomes, and ribo-peptidic complexes inside liposomes: insights into the origin of metabolism. | Here we summarize the main results of our latest investigation on the spontaneous encapsulation of proteins (ferritin) and ribosomes inside lipid vesicles. We show that when vesicles form in a solution containing some macromolecules (even at low concentration), in contrast to the expectations, a few but measurable numb... | ['Ferritins', 'Liposomes', 'Ribosomes'] | 23,080,007 | [['D12.776.157.427.249', 'D12.776.556.579.249'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['A11.284.430.214.190.875.811']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Phosphorogenic and spontaneous formation of tris(bipyridine)ruthenium in peptide scaffolds. | Redox-active ruthenium complexes have been widely used in various fields; however, the harsh conditions required for their synthesis are not always conducive to their subsequent use in biological applications. In this study, we demonstrate the spontaneous formation of a derivative of tris(bipyridine)ruthenium at 37°C t... | ['Molecular Structure', 'Organometallic Compounds', 'Oxidation-Reduction', 'Peptides', 'Photochemical Processes', 'Ruthenium'] | 30,784,138 | [['G02.111.570', 'G02.466'], ['D02.691'], ['G02.700', 'G03.295.531'], ['D12.644'], ['G02.740'], ['D01.268.556.805', 'D01.268.956.812', 'D01.552.544.805']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ipriflavone inhibits bone resorption in intact and ovariectomized rats. | The aim of this study was to investigate the possible inhibitory effect of ipriflavone on bone resorption in rats. For this purpose, 10-week-old, intact and ovariectomized (OVX) rats, prelabeled from birth with [3H]-tetracycline, were used. Bone resorption was monitored by measuring the urinary excretion of [3H]. The a... | ['Administration, Oral', 'Analysis of Variance', 'Animals', 'Bone Remodeling', 'Bone Resorption', 'Diet', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Estradiol', 'Female', 'Humans', 'Isoflavones', 'Isotope Labeling', 'Osteoporosis, Postmenopausal', 'Ovariectomy', 'Rats', 'Urine', 'Uterus'] | 9,263,609 | [['E02.319.267.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G11.427.213', 'G16.762.150'], ['C05.116.264', 'G11.427.213.150'], ['G07.203.650.240'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['D04.210.500.365.415.248', 'D06.472.334.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Love, spirituality, and regret: thematic analysis of last statements from death row, Texas (2006-2011). | Individuals awaiting execution have high rates of mental illness and psychological problems. We examined themes and psychological factors in last statements before execution in Texas between December 2006 and July 2011 (n = 79) and compared them to our previous research on last statements between April 2002 and Novembe... | ['Adolescent', 'Adult', 'Capital Punishment', 'Communication', 'Emotions', 'Humans', 'Love', 'Male', 'Middle Aged', 'Prisoners', 'Spirituality', 'Texas', 'Young Adult'] | 24,335,328 | [['M01.060.057'], ['M01.060.116'], ['I01.880.604.160'], ['F01.145.209', 'L01.143'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.734'], ['M01.060.116.630'], ['M01.729'], ['F02.880.705', 'K01.844.664.500'], ['Z01.107.567.875.760.750'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 |
A histopathological study of hearts and spleens of hamsters (Mesocricetus auratus) infected with Leptospira interrogans, serovar pyrogenes. | The effects of Leptospira interrogans on the heart and spleen of hamsters were studied histopathologically. Infected hamsters were sacrificed at 1 hour, 6 hours and on days 1, 2, 3, 4, 5 and 6 after inoculation with Leptospira interrogans serovar pyrogenes. The heart and spleen of each of the sacrificed animals were re... | ['Animals', 'Cricetinae', 'Leptospira interrogans', 'Leptospirosis', 'Myocardium', 'Necrosis', 'Rodent Diseases', 'Spleen', 'Time Factors'] | 17,121,298 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['B03.440.400.425.475.475.400', 'B03.851.475.475.400'], ['C01.150.252.400.794.511'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['C23.550.717'], ['C22.795'], ['A10.549.700', 'A15.382.520.604.700'], ['G01.910.857']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulation of structure and dynamics by disulfide bond formation in unfolded states. | During oxidative folding, the formation of disulfide bonds has profound effects on guiding the protein folding pathway. Until now, comparatively little is known about the changes in the conformational dynamics in folding intermediates of proteins that contain only a subset of their native disulfide bonds. In this compr... | ['Disulfides', 'Molecular Dynamics Simulation', 'Muramidase', 'Protein Conformation', 'Protein Folding'] | 22,414,027 | [['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D08.811.277.450.642'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Improved enrichment of functionally intact anterior pituitary cells by sequential centrifugal elutriation and density gradient sedimentation. | By centrifugal elutriation and subsequent Percoll density gradient centrifugation, we obtained highly enriched cell populations of the anterior pituitary of ovariectomized adult rats. Enrichment of somatotrophs, gonadotrophs and mammotrophs was 90%, 80% and 77%, respectively (determined by immunocytochemistry). 41% of ... | ['Animals', 'Cell Count', 'Cell Separation', 'Centrifugation', 'Centrifugation, Density Gradient', 'Female', 'Fluorescent Antibody Technique', 'Pituitary Gland, Anterior', 'Pituitary Hormone-Releasing Hormones', 'Pituitary Hormones, Anterior', 'Rats', 'Rats, Inbred Strains'] | 3,535,325 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.181'], ['E05.181.724.336', 'E05.196.941.336'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.47... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biological and chemical sulfide oxidation in a Beggiatoa inhabited marine sediment. | The ecological niche of nitrate-storing Beggiatoa, and their contribution to the removal of sulfide were investigated in coastal sediment. With microsensors a clear suboxic zone of 2-10 cm thick was identified, where neither oxygen nor free sulfide was detectable. In this zone most of the Beggiatoa were found, where th... | ['Beggiatoa', 'Chemotaxis', 'Geologic Sediments', 'Germany', 'Nitrates', 'Oceans and Seas', 'Oxidation-Reduction', 'Sulfides', 'Water Microbiology'] | 18,043,645 | [['B03.440.400.645.100', 'B03.660.250.770.100'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['G01.311.330', 'G16.500.320'], ['Z01.542.315'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.75... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
[Death due to tuberculosis requiring treatment or an accompanying disease? A contribution to the lethality and mortality of tuberculosis in Germany]. | BACKGROUND: Tuberculosis (TB) is a curable disease. Nevertheless, patients in Germany also die of TB. Although mortality is decreasing, there are indications for an increase in lethality. This observation provided the impetus for a detailed analysis that sought to investigate the validity of the statistics on deaths ca... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Alcoholism', 'Antitubercular Agents', 'Autopsy', 'Cause of Death', 'Comorbidity', 'Death Certificates', 'Delayed Diagnosis', 'Diagnosis, Differential', 'Female', 'Germany', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Risk Factors', 'Tuberculosis, Meningeal', 'Tuberculosis, ... | 22,015,487 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C25.775.100.250', 'F03.900.100.350'], ['D27.505.954.122.085.255'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.5... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'An... | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Metameric intransitivity. | There are two kinds of afterimages. In negative afterimages, looking at a blank field after staring at a colored figure gives a figure whose color is complementary to that of the original figure. Less well understood and studied is the phenomenon of induced positive afterimages, in which staring at a colored area surro... | ['Afterimage', 'Attention', 'Color', 'Color Perception', 'Figural Aftereffect', 'Fixation, Ocular', 'Form Perception', 'Humans', 'Photic Stimulation', 'Visual Perception'] | 20,436,187 | [['F02.463.593.932.073', 'G14.040'], ['F02.830.104.214'], ['G01.590.540.199'], ['F02.463.593.932.217'], ['F02.463.593.932.401', 'G14.360'], ['G14.350.253'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.723.729'], ['F02.463.593.932']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Baicalein protects PC12 cells from Aâ25 | AIMS: This study aimed to explore the protective effects and possible mechanisms of baicalein on Aâ25-35-induced toxicity.MAIN METHODS: Thioflavin-T (Th-T) dye was used to determine the effects of baicalein on Aâ25-35 aggregation in vitro. PC12 cells were stimulated with Aâ25-35, then the effects of baicalein on apopto... | ['Adenosine Triphosphate', 'Amyloid beta-Peptides', 'Animals', 'Apoptosis', 'Arginine', 'Electron Transport Complex I', 'Flavanones', 'Membrane Potential, Mitochondrial', 'Mitochondria', 'Neuroprotective Agents', 'Niacin', 'Niacinamide', 'Nitric Oxide', 'Oxidative Stress', 'PC12 Cells', 'Peptide Fragments', 'Proline', ... | 32,112,868 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['G04.146.954.035'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D05.500.562.249', 'D08.811.600.250.500.500', 'D08.811.682.608.504', 'D12.776.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of Na-coupled alanine transport on intracellular K activities and the K conductance of the basolateral membranes of Necturus small intestine. | Intracellular electrical potentials and K activity, (K)c, were determined simultaneously in Necturus small intestine before and after the addition of alanine to the mucosal solution. As noted previously (Gunter-Smith, Grasset & Schultz, 1982), the addition of alanine to the mucosal solution resulted in a prompt depolar... | ['Alanine', 'Animals', 'Biological Transport', 'Cell Membrane', 'Intestinal Mucosa', 'Intestine, Small', 'Necturus', 'Potassium', 'Sodium'] | 6,834,422 | [['D12.125.042'], ['B01.050'], ['G03.143'], ['A11.284.149'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124.684'], ['B01.050.150.900.090.608.630.510'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Knowledge, attitudes, and behavioural risk factors regarding zoonotic infections among bushmeat hunters and traders in Nsukka, southeast Nigeria. | OBJECTIVES: In light of the dramatic spread of Ebola virus in some parts of Africa and the 2014 outbreak in Nigeria, a study was conducted to evaluate bushmeat dealers' knowledge and attitudes about zoonotic infections and the risk of transmission to humans.METHODS: A cross-sectional survey was conducted in a community... | ['Animals', 'Commerce', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Meat', 'Nigeria', 'Risk Factors', 'Surveys and Questionnaires', 'Zoonoses'] | 29,909,609 | [['B01.050'], ['J01.219'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300.600', 'J02.500.600'], ['Z01.058.290.190.565'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Immunohistochemical and ultrastructural study of histiocytosis X and non-X histiocytoses. | The diagnostic reliability of ultrastructural and immunohistochemical examinations on routinely processed biopsy specimens of cutaneous histiocytic proliferations (histiocytosis X, n = 7; juvenile xanthogranuloma, n = 4; necrobiotic xanthogranuloma, n = 2; traumatic granuloma of the tongue, n = 1) was evaluated. S-100 ... | ['Adult', 'Aged', 'Female', 'Histiocytosis, Langerhans-Cell', 'Humans', 'Immunohistochemistry', 'Infant', 'Male', 'Middle Aged', 'Retrospective Studies', 'Skin', 'Skin Diseases', 'Xanthogranuloma, Juvenile', 'Xanthomatosis'] | 2,123,893 | [['M01.060.116'], ['M01.060.116.100'], ['C08.381.483.375', 'C15.604.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H0... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Improvement of wastewater treatment performance of the Fukashiba treatment plant. | The Fukashiba Treatment Plant Kashima Rinkai Specified Sewage Works has received wastewater from the petrochemical complex (90%) and public sewage of Kamisu and Hasaki town (10%). For this reason, the plant is facing many difficulties in producing good quality effluent. In order to solve these difficulties, we are revi... | ['Biodegradation, Environmental', 'Bioreactors', 'Industrial Waste', 'Japan', 'Models, Chemical', 'Nitrogen', 'Sewage', 'Waste Disposal, Fluid', 'Waste Management', 'Water Pollutants, Chemical', 'Water Purification'] | 16,862,782 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.115', 'J01.897.120.115'], ['D20.944.420', 'N06.850.460.710.420'], ['Z01.252.474.463', 'Z01.639.595'], ['E05.599.495'], ['D01.268.604', 'D01.362.625'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['N06.850.780.200.800.800.900... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Qualification of a Quantitative Method for Monitoring Aspartate Isomerization of a Monoclonal Antibody by Focused Peptide Mapping. | Aspartate (Asp) isomerization is a common post-translational modification of recombinant therapeutic proteins that can occur during manufacturing, storage, or administration. Asp isomerization in the complementarity-determining regions of a monoclonal antibody may affect the target binding and thus a sufficiently robus... | ['Amino Acid Sequence', 'Antibodies, Monoclonal', 'Aspartic Acid', 'Chromatography, High Pressure Liquid', 'Complementarity Determining Regions', 'Isomerism', 'Peptide Mapping', 'Recombinant Proteins', 'Tandem Mass Spectrometry'] | 27,091,886 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['E05.196.181.400.300'], ['D12.644.541.500.650.500.180', 'D12.776.124.486.485.680.650.500.180', 'D12.776.124.486.485.797.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Exposure to Gulf War Illness chemicals induces functional muscarinic receptor maladaptations in muscle nociceptors. | Chronic pain is a component of the multisymptom disease known as Gulf War Illness (GWI). There is evidence that pain symptoms could have been a consequence of prolonged and/or excessive exposure to anticholinesterases and other GW chemicals. We previously reported that rats exposed, for 8 weeks, to a mixture of anticho... | ['Animals', 'Chemical Warfare Agents', 'Chlorpyrifos', 'Chronic Pain', 'Disease Models, Animal', 'Ganglia, Spinal', 'Gene Expression Regulation', 'Male', 'Membrane Potentials', 'Muscarinic Agonists', 'Muscle, Skeletal', 'Neurons', 'Nociceptors', 'Pain Threshold', 'Permethrin', 'Potassium Channel Blockers', 'Potassium C... | 27,058,124 | [['B01.050'], ['D27.720.777.300', 'D27.888.569.612.150', 'J01.637.870.900.200'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['C23.888.592.612.274'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.308'], ['G01.154.535', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Some epidemiological aspects of diphtheria in Malaysia. | In Malysia, the proportion of children fully immunized againest diphtheria is generally low (20%). On the other hand, the Schick conversion rate rises with age and reaches 90% by 11 years of age. It is noted that asymptomatic carriers are an important epidemiological factor in diphtheria and that carrier rates for scho... | ['Carrier State', 'Child', 'Diphtheria', 'Female', 'Humans', 'Malaysia', 'Male'] | 1,006,789 | [['N06.850.520.169'], ['M01.060.406'], ['C01.150.252.410.040.246.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.487']] | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Role of platelet-activating factor in leukocyte-independent plasma extravasation and mast cell activation during endotoxemia. | BACKGROUND: Independently from leukocyte adherence, endothelial factors and mast cell activation seems to promote microvascular permeability. Platelet-activating factor (PAF) has been shown to play a significant role in endotoxin-induced leukocyte adherence. The aim of our study was to investigate if there is also a ro... | ['Animals', 'Blood', 'Capillary Permeability', 'Cell Adhesion', 'Diterpenes', 'Endotoxemia', 'Endotoxins', 'Ginkgolides', 'Hemodynamics', 'Lactones', 'Leukocytes', 'Macromolecular Substances', 'Male', 'Mast Cells', 'Platelet Activating Factor', 'Platelet Membrane Glycoproteins', 'Polysaccharides', 'Rats', 'Rats, Wistar... | 11,027,469 | [['B01.050'], ['A12.207.152', 'A15.145'], ['G03.143.330', 'G09.330.165'], ['G04.022'], ['D02.455.849.291'], ['C01.757.100.275', 'C01.861.375', 'C23.550.470.790.500.100.275'], ['D23.946.123.329'], ['D02.455.849.291.400'], ['G09.330.380'], ['D02.540'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['D05'], ['A11.329... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Depletion of a gamma delta T cell subset can increase host resistance to a bacterial infection. | Gammadelta T lymphocytes have been shown to regulate immune responses in diverse experimental systems. Because distinct gammadelta T cell subsets, as defined by the usage of certain TCR V genes, preferentially respond in various diseases and disease models, we have hypothesized that the various gammadelta T cell subset... | ['Animals', 'Antibodies, Monoclonal', 'Female', 'Gene Targeting', 'Immunity, Cellular', 'Immunity, Innate', 'Injections, Intravenous', 'Listeria monocytogenes', 'Listeriosis', 'Liver', 'Lymphocyte Depletion', 'Male', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Receptors, Antigen, T-Cell, gamma-... | 11,086,087 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.393.335'], ['G12.450.050.400'], ['G12.450.564'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'], ['C01.150.252.410.514'], ['A0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hip aspiration: verification of needle position by air arthrography. | A new method is described for verification of needle placement during hip aspiration or hip arthrography using suction air arthrography. The method is safe, rapid, reliable, and reproducible, and it eliminates problems with obscuring pathology by incorrect injection of dye or air, reactions to dye, or air embolism. | ['Arthrography', 'Biopsy, Needle', 'Child', 'Hip Joint', 'Humans'] | 3,793,918 | [['E01.370.350.700.070'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['M01.060.406'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fabrication of a functional palatal saliva reservoir by using a resilient liner during processing of a complete denture. | One of the major problems associated with xerostomic patients is the poor tolerance and retention of removable dental prostheses because of thin dry atrophic mucosa and lack of a saliva film. The use of salivary substitutes can improve lubrication, provide irrigation for dry mucosa, provide significant relief from symp... | ['Denture Design', 'Denture Liners', 'Denture, Complete, Upper', 'Humans', 'Mouth, Edentulous', 'Palate, Hard', 'Saliva, Artificial', 'Xerostomia'] | 23,107,242 | [['E06.780.346.760.300', 'E06.912.250'], ['E06.780.346.760.357', 'E07.695.190.200.210'], ['E06.780.346.760.775.504', 'E07.695.190.200.205.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465.550', 'C07.793.597'], ['A02.835.232.781.324.502.660', 'A14.521.658.660', 'A14.549.617.660'], ['D25.583.820', 'J01.63... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Histochemical and biochemical studies on the secretory mechanisms of some glands of guinea-pigs treated with histamine. | The experiments were carried out on 60 mature male guinea-pigs, randomly allocated into six groups. Animals from Group I (control) received intracardiac injections of 0.25 cm3 0.9% NaCl, while animals from all other groups received intracardiac injections of histamine after the intraperitoneal application of H1, H2 and... | ['Adrenal Glands', 'Animals', 'Endocrine Glands', 'Exocrine Glands', 'Guinea Pigs', 'Histamine', 'Histamine H1 Antagonists', 'Histamine H2 Antagonists', 'Ipratropium', 'Male', 'Muscarinic Antagonists', 'Pancreas', 'Parotid Gland', 'Pyrilamine', 'Ranitidine', 'Thyroid Gland', 'Tissue Fixation'] | 12,056,651 | [['A06.300.071'], ['B01.050'], ['A06.300'], ['A10.336'], ['B01.050.150.900.649.313.992.550'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['D27.505.519.625.375.425.400', 'D27.505.696.577.375.425.400'], ['D27.505.519.625.375.425.425', 'D27.505.696.577.375.425.425'], ['D02.145.07... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Promoting equity through integrated early child development and nutrition interventions. | Sustainable development, a foundation of the post-2015 global agenda, depends on healthy and productive citizens. The origins of adult health begin early in life, stemming from genetic-environmental interactions that include adequate nutrition and opportunities for responsive learning. Inequities associated with inadeq... | ['Child Development', 'Child Nutritional Physiological Phenomena', 'Child, Preschool', 'Conservation of Natural Resources', 'Early Medical Intervention', 'Humans'] | 24,571,211 | [['F01.525.200', 'G07.345.374.750'], ['G07.203.650.220'], ['M01.060.406.448'], ['J01.256', 'N06.230.080'], ['N02.421.726.363'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
A novel strategy for retrospective exposure assessment in the Norwegian silicon carbide industry. | The objective was to construct a retrospective job-exposure matrix (JEM) for the Norwegian silicon carbide industry. More than 3300 historical total dust measurements were available (1967-2005); however, there were few measurements of other agents. Total dust measurements were therefore used as the basis for the JEM, a... | ['Air Pollutants, Occupational', 'Carbon Compounds, Inorganic', 'Dust', 'Humans', 'Inhalation Exposure', 'Job Description', 'Linear Models', 'Norway', 'Occupational Exposure', 'Quartz', 'Silicon Compounds', 'Silicon Dioxide', 'Time Factors'] | 22,448,628 | [['D27.888.284.101.268'], ['D01.200'], ['D20.633.222'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.112'], ['N04.452.677.410'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Improving resolution of dynamic communities in human brain networks through targeted node removal. | Current approaches to dynamic community detection in complex networks can fail to identify multi-scale community structure, or to resolve key features of community dynamics. We propose a targeted node removal technique to improve the resolution of community detection. Using synthetic oscillator networks with well-defin... | ['Adult', 'Algorithms', 'Brain', 'Brain Mapping', 'Humans', 'Magnetic Resonance Imaging'] | 29,261,662 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Detection of epithelial carcinoma cells in the blood of patients with gynaecological malignancies. | BACKGROUND: Some investigations have shown that evidence of epithelial tumor cells in bone marrow is a relevant prognostic factor in various solid tumors. However there is a lack of data concerning the value of detection methods for epithelial cells in the serum of cancer patients.MATERIALS AND METHODS: In a prospectiv... | ['Adult', 'Aged', 'Aged, 80 and over', 'Epithelial Cells', 'Female', 'Genital Diseases, Female', 'Genital Neoplasms, Female', 'Humans', 'Immunohistochemistry', 'Keratins', 'Middle Aged', 'Neoplasm Staging', 'Predictive Value of Tests'] | 12,820,353 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A11.436'], ['C13.351.500'], ['C04.588.945.418', 'C13.351.937.418'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Elevated pim-1 and c-myc proto-oncogene induction in B lymphocytes from BLV-infected cows with persistent B lymphocytosis. | Bovine leukemia virus (BLV) induces a non-malignant, polyclonal, persistent lymphocytosis (PL) of circulating, CD5 B lymphocytes in cattle, with variable progression to CD5 B cell leukemia or lymphoma. We analyzed the expression of two proto-oncogenes, pim-1 and c-myc, proto-oncogenes deregulated in some human B cell l... | ['Animals', 'B-Lymphocytes', 'Cattle', 'Enzootic Bovine Leukosis', 'Female', 'Gene Expression Regulation', 'Genes, myc', 'Humans', 'Interleukin-2', 'Ionomycin', 'Lymphocytosis', 'Mice', 'Protein-Serine-Threonine Kinases', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-pim-1', 'Proto-Oncogenes', 'Tetradecanoylpho... | 8,847,898 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['B01.050.150.900.649.313.500.380.271'], ['C01.925.782.815.200.260', 'C04.557.337.100', 'C20.673.483.260', 'C22.196.260'], ['G05.308'], ['G05.360.340.024.340.375.500.791.420'], ['B01.05... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Identical results of primary percutaneous transluminal coronary angioplasty in patients with acute myocardial infarction admitted as a result of direct or indirect referral]. | OBJECTIVE: Description of the results of primary percutaneous transluminal coronary angioplasty (PTCA) in the management of acute myocardial infarction.DESIGN: Prospective, descriptive.METHOD: Data were collected on case record forms of consecutive patients with an acute myocardial infarction who in 1990-1997 were refe... | ['Angioplasty, Balloon, Coronary', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Netherlands', 'Outcome and Process Assessment, Health Care', 'Patient Transfer', 'Prospective Studies', 'Recurrence', 'Referral and Consultation', 'Survival Rate'] | 10,321,261 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Scanning electron microscope studies of rabbit aortic endothelium in areas of haemodynamic stress during induction of fatty streaks. | Young male rabbits were fed a diet containing 0.2% cholesterol for 4, 6, 12 and 20 weeks. At death the aortas of each animal were prepared for scanning electron microscopy (SEM) and the size of the atherosclerotic lesions surrounding the aortic ostia was measured by planimetry. Under SEM the early fatty lesions appeare... | ['Animals', 'Aorta', 'Arteriosclerosis', 'Cholesterol', 'Diet, Atherogenic', 'Endothelium', 'Male', 'Microscopy, Electron, Scanning', 'Rabbits', 'Stress, Mechanical', 'Time Factors'] | 148,152 | [['B01.050'], ['A07.015.114.056'], ['C14.907.137.126'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['G07.203.650.240.242'], ['A10.272.491'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B01.050.150.900.649.313.968.700'], ['G01.374.835'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparatory versus main competitions: differences in performances, lactate responses and pre-competition plasma cortisol concentrations in elite male swimmers. | Two groups of elite male swimmers were studied using a similar protocol during the winter training seasons of two consecutive years. In the first season (September 1997-January 1998), eight male swimmers (age 19-25 years) of the Italian National Team participated, after 12 weeks of increased training volume, in a prepa... | ['Adult', 'Humans', 'Hydrocortisone', 'Lactic Acid', 'Male', 'Physical Fitness', 'Swimming'] | 10,985,589 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D02.241.511.459.450'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400.545'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I03.350.875', 'I03.450.642.845... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The use of biochemical and immunological parameters in nutritional screening and assessment. | OBJECTIVE: To evaluate the relationship between serum albumin, total cholesterol and total lymphocyte count with two nutritional assessment methods, to verify if their use is justified in nutritional screening tools.METHODS: 101 patients admitted to medical/surgical wards underwent the SGA and the Full Nutritional Asse... | ['Aged', 'Analysis of Variance', 'Body Mass Index', 'Cholesterol', 'Female', 'Humans', 'Lymphocyte Count', 'Male', 'Malnutrition', 'Middle Aged', 'Nutrition Assessment', 'Nutritional Status', 'Patients', 'Physical Examination', 'Serum Albumin', 'Weight Loss'] | 21,892,580 | [['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High-Definition and Non-invasive Brain Modulation of Pain and Motor Dysfunction in Chronic TMD. | BACKGROUND: Temporomandibular disorders (TMD) have a high prevalence and in many patients pain and masticatory dysfunction persist despite a range of treatments. Non-invasive brain neuromodulatory methods, namely transcranial direct current stimulation (tDCS), can provide relatively long-lasting pain relief in chronic ... | ['Adult', 'Aged', 'Brain', 'Chronic Pain', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Motor Cortex', 'Motor Skills Disorders', 'Pain Management', 'Pain Measurement', 'Single-Blind Method', 'Temporomandibular Joint Disorders', 'Transcranial Direct Current Stimulation'] | 26,226,938 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['C23.888.592.612.274'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624']... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The prevalence of selected potentially hazardous workplace exposures in the US: findings from the 2010 National Health Interview Survey. | OBJECTIVE: Assess the national prevalence of current workplace exposure to potential skin hazards, secondhand smoke (SHS), and outdoor work among various industry and occupation groups. Also, assess the national prevalence of chronic workplace exposure to vapors, gas, dust, and fumes (VGDF) among these groups.METHODS: ... | ['Adult', 'Age Distribution', 'Aged', 'Air Pollutants, Occupational', 'Cross-Sectional Studies', 'Female', 'Hazardous Substances', 'Health Surveys', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Occupational Diseases', 'Occupational Exposure', 'Occupational Health', 'Occupations', 'Prevalence', 'Risk Assessm... | 22,821,700 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['D27.888.284.101.268'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D27.888.426'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[A study of clinical significance of leukocyte migration inhibition test in drug-induced hypersensitivity pneumonitis]. | In 71 patients suspected of drug-induced pneumonitis, the identification of the allergenic drugs were studied by leukocyte migration inhibition test (LMIT). The LMIT was positive in 61 cases (85.9%). Leukocyte migration activating factor (LMAF) was detected in 22 cases (30.9%), and leukocyte migration inhibitory factor... | ['Adolescent', 'Adult', 'Aged', 'Alveolitis, Extrinsic Allergic', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Cell Migration Inhibition', 'Child', 'Drugs, Chinese Herbal', 'Female', 'Humans', 'Hypersensitivity, Delayed', 'Lactams', 'Male', 'Middle Aged', 'Pulmonary Eosinophilia'] | 8,871,295 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C08.381.483.125', 'C08.674.055', 'C20.543.480.680.075'], ['D27.505.954.122.085'], ['D27.505.954.122'], ['G04.198.337'], ['M01.060.406'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.418'], ['D02.065.589', 'D03.38... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Whole-genome sequencing of quartet families with autism spectrum disorder. | Autism spectrum disorder (ASD) is genetically heterogeneous, with evidence for hundreds of susceptibility loci. Previous microarray and exome-sequencing studies have examined portions of the genome in simplex families (parents and one ASD-affected child) having presumed sporadic forms of the disorder. We used whole-gen... | ['Adult', 'Child', 'Child Development Disorders, Pervasive', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Parents', 'Sequence Analysis, DNA', 'Siblings'] | 25,621,899 | [['M01.060.116'], ['M01.060.406'], ['F03.625.164'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.393.760.700'], ['F01.829.263.500.490', 'I01.880.853.150.500.505', 'M01.781']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Duration of enhanced responsiveness upon re-exposure to ozone. | It has been repeatedly observed that ozone (O3) re-exposure within 24 h elicits enhanced pulmonary function responses. However, there are only limited observations concerning re-exposure to O3 at intervals between 24 h and several days. The present study was designed to assess the effects of re-exposure to 0.35 ppm O3 ... | ['Adaptation, Physiological', 'Adult', 'Air Pollutants', 'Airway Resistance', 'Exercise', 'Forced Expiratory Flow Rates', 'Forced Expiratory Volume', 'Humans', 'Lung', 'Male', 'Oxygen Consumption', 'Ozone', 'Plethysmography, Whole Body', 'Random Allocation', 'Time Factors', 'Vital Capacity'] | 2,782,945 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['D27.888.284.101'], ['E01.370.386.700.050', 'G09.772.060'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.386.700.660.225', 'G09.772.650.300'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['G03.680'], ['D01.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Recombinant Metridia luciferase isoforms: expression, refolding and applicability for in vitro assay. | The recombinant coelenterazine-dependent luciferases (isoforms MLuc164 and MLuc39) from the marine copepod Metridia longa were expressed as inclusion bodies in E. coli cells, dissolved in 6 M guanidinium chloride and folded in conditions developed for proteins containing intramolecular disulfide bonds. One of them (MLu... | ['Amino Acid Sequence', 'Animals', 'Copepoda', 'Gene Expression', 'Isoenzymes', 'Kinetics', 'Luciferases', 'Molecular Sequence Data', 'Protein Folding', 'Recombinant Proteins', 'Sequence Alignment', 'Spectrometry, Fluorescence'] | 18,754,048 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.131.365.160'], ['G05.297'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.517', 'D12.776.532.510'], ['L01.453.245.667'], ['G01.154.651', 'G02.111.688'], ['D12.776.828'], ['E05.393.751'], ['E05.196.712.516.600.676... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Orthokeratology lens-related Pseudomonas aeruginosa infectious keratitis. | PURPOSE: To report a case of orthokeratology lens-related Pseudomonas corneal ulcer in an adult.METHODS: Case report.RESULTS: A 37-year-old man presented with a 1-day history of painful red eye. He was a soft contact lens wearer before he started on nocturnal orthokeratology lens wear of 8 to 10 hours per night 9 month... | ['Adult', 'Anti-Bacterial Agents', 'Ceftazidime', 'Contact Lenses', 'Cornea', 'Corneal Ulcer', 'Drug Therapy, Combination', 'Eye Infections, Bacterial', 'Humans', 'Male', 'Myopia', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Tobramycin', 'Visual Acuity'] | 12,658,097 | [['M01.060.116'], ['D27.505.954.122.085'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['E07.632.500.276'], ['A09.371.060.217'], ['C01.375.177', 'C11.204.564.225', 'C11.294.177'], ['E02.319.310'], ['C01.150.252.289', 'C01.375.354', 'C11.294.354'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Active intervals between sets of resistance exercises potentiate the magnitude of postexercise hypotension in elderly hypertensive women. | Active and passive intervals (AI, PI) between exercise series promote different hemodynamic responses; however, the impact of these intervals on the blood pressure response has not yet been investigated. The objective of this study was to compare the impact of AIs and PIs during resistance exercises with the magnitude ... | ['Aging', 'Female', 'Heart Rate', 'Humans', 'Hypertension', 'Lower Extremity', 'Middle Aged', 'Physical Exertion', 'Post-Exercise Hypotension', 'Resistance Training', 'Rest', 'Upper Extremity'] | 21,993,035 | [['G07.345.124'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['A01.378.610'], ['M01.060.116.630'], ['G11.427.683'], ['C10.177.575.600.537', 'C14.907.514.611'], ['E02.760.169.063.500.387.875', 'E02.779.483.875', 'E02.831.535.483.875', 'G11.427.410.698.27... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Climatic changes lead to declining winter chill for fruit and nut trees in California during 1950-2099. | BACKGROUND: Winter chill is one of the defining characteristics of a location's suitability for the production of many tree crops. We mapped and investigated observed historic and projected future changes in winter chill in California, quantified with two different chilling models (Chilling Hours, Dynamic Model).METHOD... | ['California', 'Climate', 'Cold Temperature', 'Seasons', 'Trees'] | 19,606,220 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['B01.650.9... | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Some general considerations of a human-based medicine's palliative approach to the vulnerability of the multiply disabled child before the end of life. | Specificities of situation of individuals with multiple disabilities and pediatric neurological pathologies call for specialized and multi-field competences that are commonly allowed and disallowed in contemporary clinical contexts. However what must be questioned in this matter is not only the meaning of the clinical,... | ['Child', 'Disabled Children', 'Humans', 'Palliative Medicine', 'Terminal Care', 'Vulnerable Populations'] | 24,385,205 | [['M01.060.406'], ['M01.150.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.645'], ['E02.760.905', 'N02.421.585.905'], ['M01.965']] | ['Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Determination of organophosphate and carbamate pesticides in spiked samples of tap water and fruit juices by a biosensor with photothermal detection. | The determination of organophosphate (paraoxon, chlorpyrifos, diazinon) and carbamate (carbaryl, carbofuran) pesticides in spiked drinking water and fruit juices was carried out using a photothermal biosensor. The biosensor consists of a cartridge containing immobilised enzyme acetylcholinesterase (AChE) placed in a fl... | ['Beverages', 'Biosensing Techniques', 'Carbamates', 'Flow Injection Analysis', 'Food Analysis', 'Food Contamination', 'Fruit', 'Insecticides', 'Organophosphorus Compounds', 'Photochemistry', 'Water Pollutants, Chemical', 'Water Supply'] | 11,459,102 | [['G07.203.100', 'J02.200'], ['E05.601.043'], ['D02.241.081.251'], ['E05.196.460'], ['E05.362', 'J01.576.423.850.100'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D02.705'], ['H01.181.529.711... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Metabolic acidosis in calves with diarrhea and treatment with NaHCO3]. | Sixteen head of 7 to 10 days old calves of the Black-Pied breed with clinical diagnosis of gastroenteritis acuta were examined for their clinical and laboratory findings before i. v. application of 8.4% solution of NaHCO3 and after it, using the well-known formula: live weight in kg x 0.6 x base deficit. The calves pre... | ['Acidosis', 'Animals', 'Cattle', 'Cattle Diseases', 'Diarrhea', 'Sodium Bicarbonate'] | 8,975,452 | [['C18.452.076.176'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C23.888.821.214'], ['D01.200.275.150.100.800', 'D01.857.625']] | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A feeling that needs expressing. Helping patients manage their anxiety. | Illness often causes high levels of anxiety, which can have a detrimental effect on recovery. Nurses can do much within their normal relationships with their patients to alleviate this. | ['Adaptation, Psychological', 'Adult', 'Anxiety', 'Communication', 'Female', 'Humans', 'Male', 'Middle Aged'] | 2,343,053 | [['F01.058'], ['M01.060.116'], ['F01.470.132'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
TLR2 sensing of F. nucleatum and S. sanguinis distinctly triggered gingival innate response. | Gingival tissue faces constant exposure to micro-organisms. It functions as part of the host response, an anti-microbial barrier that recognizes and discriminates between commensal and pathogenic bacteria. This study aimed to evaluate and compare the effects of cell wall extracts from different periodontal bacteria, co... | ['Biomarkers', 'Cell Wall', 'Cells, Cultured', 'Fusobacterium nucleatum', 'Gene Silencing', 'Gingiva', 'Humans', 'Immunity, Innate', 'Inflammation', 'Interleukin-8', 'Keratinocytes', 'Matrix Metalloproteinase 9', 'RNA Interference', 'Signal Transduction', 'Streptococcus sanguis', 'Toll-Like Receptor 2', 'beta-Defensins... | 19,299,164 | [['D23.101'], ['A11.284.183'], ['A11.251'], ['B03.370.250.500', 'B03.440.425.410.420.500'], ['G05.308.203.374'], ['A14.549.167.646.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.564'], ['C23.550.470'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D12.776.467.374.200.120.800', 'D12.776.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lithium clearance in water immersion-induced natriuresis in humans. | Lithium clearance (CLi) has been advanced as a measure of sodium delivery from the proximal tubules. Because information on the intrarenal effects of water immersion is only limited, and available data are conflicting with respect to the effects on the proximal tubule, we examined the effects of 3 h of water immersion ... | ['Adult', 'Female', 'Humans', 'Immersion', 'Kidney Tubules', 'Lithium', 'Male', 'Natriuresis'] | 2,732,165 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.466'], ['A05.810.453.736.560'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['G08.852.179.557']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification and characterisation of the ecdysone biosynthetic genes neverland, disembodied and shade in the salmon louse Lepeophtheirus salmonis (Copepoda, Caligidae). | The salmon louse is a marine ectoparasitic copepod on salmonid fishes. Its lifecycle consists of eight developmental stages, each separated by a molt. In crustaceans and insects, molting and reproduction is controlled by circulating steroid hormones such as 20-hydroxyecdysone. Steroid hormones are synthesized from chol... | ['Amino Acid Sequence', 'Animals', 'Chromatography, Liquid', 'Cloning, Molecular', 'Copepoda', 'Ecdysone', 'Female', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Salmon', 'Sequence Homology, Amino Acid', 'Tandem Mass Spectrometry'] | 29,401,467 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.181.400'], ['E05.393.220'], ['B01.050.500.131.365.160'], ['D04.210.500.247.222.265.165.500', 'D06.472.445.573.271.500'], ['D13.444.735.544'], ['E05.393.620.500.706'], ['B01.050.150.900.493.817.750.705'], ['G02.111.810.200', 'G05.810.200'], ['E05.196.56... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Characterization of pig liver purified cytochrome P-450 isoenzymes for ochratoxin A metabolism studies. | In this paper, we report the characterization of 4 isolated, constitutive cytochrome P-450 fractions from pig liver microsomes. The two predominant forms, A2 and A3, exhibit several similarities: a Mr of 54 kDa, a lambda max CO-Fe++ at 448 nm, a relatively high ratio of the high-spin form and an immunological cross-rea... | ['Animals', 'Chromatography, High Pressure Liquid', 'Cytochrome P-450 Enzyme System', 'Isoenzymes', 'Microsomes, Liver', 'Ochratoxins', 'Swine'] | 1,853,365 | [['B01.050'], ['E05.196.181.400.300'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D08.811.348', 'D12.776.800.300'], ['A11.284.835.540.541'], ['D03.383.663.283.446.800.500', 'D03.633.100.150.446.800.500', 'D23.946.587.697'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protein quality control: from mechanism to disease : EMBO Workshop, Costa de la Calma (Mallorca), Spain, April 28 - May 03, 2019. | The cellular protein quality control machinery with its central constituents of chaperones and proteases is vital to maintain protein homeostasis under physiological conditions and to protect against acute stress conditions. Imbalances in protein homeostasis also are keys to a plethora of genetic and acquired, often ag... | ['Animals', 'Cells, Cultured', 'Homeostasis', 'Humans', 'Molecular Chaperones', 'Protein Folding', 'Proteostasis', 'Proteostasis Deficiencies', 'Spain'] | 31,713,048 | [['B01.050'], ['A11.251'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.580'], ['G01.154.651', 'G02.111.688'], ['G02.111.730', 'G03.816'], ['C18.452.845'], ['Z01.542.846']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Does entry test make any difference on the future performance of medical students? | OBJECTIVE: To observe the influence/efficiency of entry test in the selection of students for MBBS. To see the effect of FSC and Entry test marks on the future performance of students in the coming years.METHODS: This was an Analytical Prospective Longitudinal study carried out in a private medical college from Decembe... | ['Adult', 'Education, Medical', 'Educational Measurement', 'Educational Status', 'Female', 'Forecasting', 'Humans', 'Longitudinal Studies', 'Male', 'Pakistan', 'Prospective Studies', 'School Admission Criteria', 'Sex Factors', 'Students, Medical'] | 23,866,511 | [['M01.060.116'], ['I02.358.399'], ['I02.399'], ['N01.824.196'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['Z01.252.245.723'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.7... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effects of exposure on discrimination of similar stimuli and on memory for their unique and common features. | Human participants received exposure to similar visual stimuli (AW and BW) that shared a common feature (W). Experiment 1 demonstrated that subsequent discrimination between AW and BW was more accurate when the two stimuli were preexposed on an intermixed schedule (AW, BW, AW, BW…) than when they were preexposed on a b... | ['Discrimination Learning', 'Discrimination, Psychological', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Reaction Time', 'Recognition, Psychology'] | 22,417,278 | [['F02.463.425.280'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.425.540.706']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A statistical model of the VA/Q distribution. | A "blocks model" is proposed to model the distribution of the ventilation-perfusion ratio (VA/Q distribution). This model is developed from statistical principles and enables the estimated VA/Q distribution to be interpreted in a straightforward and intuitive manner. Estimation of parameters of the blocks model uses a ... | ['Computer Simulation', 'Humans', 'Models, Biological', 'Models, Statistical', 'Monte Carlo Method', 'Noble Gases', 'Pulmonary Gas Exchange', 'Respiratory Dead Space', 'Ventilation-Perfusion Ratio'] | 2,168,364 | [['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['D01.268.613', 'D01.362.641'], ['E01.370.386.700.650', 'G03.143.775... | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
In vitro effect of DNA topoisomerase inhibitors on Candida albicans. | In this study we investigated the in vitro antifungal activity of 10 DNA topoisomerase inhibitors on the growth of Candida albicans. The EUCAST broth microdilution method was used to determine the minimum inhibitory concentrations (MICs) of the compounds for C. albicans. In addition, the effect of the inhibitors on the... | ['Antifungal Agents', 'Candida albicans', 'Enzyme Inhibitors', 'Fungal Proteins', 'Humans', 'Hyphae', 'Microbial Sensitivity Tests', 'Microscopy', 'Topoisomerase I Inhibitors', 'Yeasts'] | 19,626,543 | [['D27.505.954.122.136'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D27.505.519.389'], ['D12.776.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A19.687.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Melanoma of the foot. | We performed a prospective study of the results of treatment of primary cutaneous melanoma of the foot in 282 patients to determine if there were any factors that could predict survival. These patients were part of a group of 1018 patients who had primary cutaneous melanoma affecting the lower extremity. We found that ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Foot Diseases', 'Humans', 'Male', 'Melanoma', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Invasiveness', 'Prognosis', 'Skin Neoplasms', 'Survival Analysis'] | 8,200,896 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.360', 'C17.800.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.83... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased expression of HMGB1 is associated with poor prognosis in human bladder cancer. | BACKGROUND AND OBJECTIVE: High-mobility group box 1 (HMGB1) is a versatile protein with intranuclear and extracellular functions that is involved in numerous biological and pathological processes, such as transcription, DNA repair, and response to infection and inflammation. HMGB1 overexpression has been reported in a ... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Cohort Studies', 'Disease-Free Survival', 'Female', 'Gene Expression Regulation, Neoplastic', 'HMGB1 Protein', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Grading', 'Neoplasm Staging', 'Predictive Value of T... | 22,237,993 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['G05.308.370'], ['D12.776.26... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Discordance between Physician and the General Public Perceptions of Prognostic Disclosure to Children with Serious Illness: a Korean Nationwide Study. | Background: It is difficult to decide whether to inform the child of the incurable illness. We investigated attitudes of the general population and physicians toward prognosis disclosure to children and associated factors in Korea.Methods: Physicians working in one of 13 university hospitals or the National Cancer Cent... | ['Adult', 'Critical Illness', 'Disclosure', 'Female', 'Hospitals, University', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Palliative Care', 'Perception', 'Physicians', 'Prognosis', 'Religion', 'Republic of Korea', 'Surveys and Questionnaires'] | 30,505,258 | [['M01.060.116'], ['C23.550.291.625'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', '... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Spatiotemporal evolution of global population ageing from 1960 to 2017. | BACKGROUND: Population ageing is an increasingly severe global issue. And this has been posing challenges for public health policies and medical resource allocation There are various features of population ageing in different regions worldwide.METHODS: All data were obtained from the health data of World Bank Open Data... | ['Aged', 'Bayes Theorem', 'Humans', 'Internationality', 'Population Dynamics', 'Spatio-Temporal Analysis'] | 30,700,286 | [['M01.060.116.100'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['E05.318.740.933.500', 'N05.715.360.750.746.500', 'N06.850.520.830.933.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Autologous platelet-rich plasma versus conventional therapy for the treatment of chronic venous leg ulcers: A comparative study. | BACKGROUND: Chronic venous leg ulcers drastically reduce the quality of life of affected patients. There is heightened interest in autologous platelet-rich plasma (PRP) as one of the promising therapies for leg ulcers.AIM: Our aim was to compare the clinical efficacy of PRP in the management of chronic venous leg ulcer... | ['Adult', 'Bandages', 'Chronic Disease', 'Debridement', 'Female', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Pain', 'Pain Measurement', 'Platelet-Rich Plasma', 'Stockings, Compression', 'Treatment Outcome', 'Varicose Ulcer', 'Young Adult'] | 28,834,103 | [['M01.060.116'], ['E07.101'], ['C23.550.291.500'], ['E04.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E01.370.600.550.324'], ['A12.207.152.693.600', 'A12.207.270.695.600', 'A15.145.693.600'], ['E07.101.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cerebrospinal fluid sodium concentration and osmosensitive sites related to arterial pressure in anaesthetized rats. | Intracerebroventricular injection of hypertonic saline induces experimental hypertension. To measure [Na] in the vicinity of osmosensitive sites, we continuously measured [Na] in cerebrospinal fluid ([Na]csf) in the lateral ventricle (LV, n = 6), in the third ventricle (V3, n = 6) and in the medial preoptic nucleus (MP... | ['Anesthesia', 'Animals', 'Binding Sites', 'Blood Pressure', 'Cerebral Ventricles', 'Heart Rate', 'Hypertension', 'Injections, Intraventricular', 'Intracranial Pressure', 'Male', 'Microelectrodes', 'Rats', 'Rats, Wistar', 'Saline Solution, Hypertonic', 'Sodium', 'Water-Electrolyte Balance'] | 8,927,496 | [['E03.155'], ['B01.050'], ['G02.111.570.120'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A08.186.211.140'], ['E01.370.600.875.500', 'G09.330.380.500'], ['C14.907.489'], ['E02.319.267.530.550'], ['G11.561.170.505'], ['E07.305.250.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diabetic retinopathy in chronic pancreatitis. | Using fluorescein angiography, we studied the prevalence and characteristics of diabetic retinopathy in 40 patients with chronic pancreatitis complicated by diabetes and in 40 type 1 diabetics with comparable duration of diabetes. Retinopathy was found in 19 pancreatitis patients (47.5%) and in 20 type 1 diabetic patie... | ['Blood Glucose', 'Cholesterol', 'Chronic Disease', 'Diabetes Mellitus, Type 1', 'Diabetic Retinopathy', 'Female', 'Fluorescein Angiography', 'Glycated Hemoglobin A', 'Humans', 'Male', 'Middle Aged', 'Pancreatitis', 'Prevalence', 'Retinal Vessels', 'Time Factors'] | 2,338,195 | [['D09.947.875.359.448.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C23.550.291.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E01.370.370.050.350', 'E01.370.380.250'], ['D09.400.430.937', 'D12.776.124.400... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of chloroquine on intestinal lipid metabolism. | Most studies that have quantitated recovery of infused lipid in the intestinal mucosa and mesenteric lymph have only been able to recapture 50-75%. One possibility is that the missing lipid enters a triacylglycerol (TG) storage pool in the enterocyte and is hydrolyzed by lysosomal lipase, and the free fatty acid releas... | ['Animals', 'Biological Transport', 'Carbon Radioisotopes', 'Chloroquine', 'Chylomicrons', 'Intestinal Mucosa', 'Lipid Metabolism', 'Lymph', 'Male', 'Rats', 'Tissue Distribution', 'Triglycerides', 'Triolein', 'Tritium'] | 3,688,229 | [['B01.050'], ['G03.143'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D03.633.100.810.050.180'], ['D10.532.183', 'D12.776.521.242'], ['A03.556.124.369', 'A10.615.550.444'], ['G03.458'], ['A12.207.270.606', 'A15.382.520.150'], ['B01.050.150.900.649.313.992.635.505.700'], ['G03.787.917', 'G07.690.72... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Management of neurological complications of carotid artery stenting. | PURPOSE: To review the neurological complications associated with extracranial carotid artery stenting and to preliminarily assess techniques used to manage these complications.METHODS: Between April 1994 and August 2000, 450 patients (270 men; mean age 70.2 years, range 27-89) had stents implanted to treat 472 cervica... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Vessel Prosthesis Implantation', 'Carotid Artery, Common', 'Carotid Stenosis', 'Cervix Uteri', 'Equipment Failure Analysis', 'Equipment Safety', 'Female', 'Follow-Up Studies', 'Humans', 'Ischemic Attack, Transient', 'Male', 'Middle Aged', 'Nervous System Diseases', 'Postope... | 11,552,726 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.100.814.868.500', 'E04.650.200'], ['A07.015.114.186.200'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['A05.360.319.679.256'], ['E05.325.192'], ['E05.330'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Amniotic fluid testosterone and follicle-stimulating hormone in the determination of fetal sex. | To determine whether hormone analysis could be used for accurate determination of fetal sex, we measured testosterone (T) and follicle-stimulating hormone (FSH) in 130 amniotic fluid samples at midgestation. The mean unconjugated T in amniotic fluid of 73 patients carrying male fetuses was 202 pg. per milliliter (95 pe... | ['Amniotic Fluid', 'Female', 'Follicle Stimulating Hormone', 'Humans', 'Pregnancy', 'Sex Determination Analysis', 'Testosterone'] | 879,210 | [['A12.098', 'A16.378.149'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E01.370.225.996', 'E05.200.996', 'E05.393.285.830'], ['D04.210.500.054.079.429.824', 'D06.472.334.851.968.984']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medium optimization of transformed root cultures of Stizolobium hassjoo producing L-DOPA with response surface methodology. | Medium optimization of B5 medium for hairy root cultures producing secondary metabolites was studied through statistical experimental design. Transformed root cultures of Stizolobium hassjoo producing L-DOPA were used as a model system. The serial dilution experiments facilitated logical choice of the upper and lower b... | ['Culture Media', 'Fabaceae', 'Levodopa', 'Plant Roots', 'Plants, Medicinal', 'Surface Properties'] | 11,101,347 | [['D27.720.470.305', 'E07.206'], ['B01.650.940.800.575.912.250.401'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.200.480', 'D12.125.072.050.685.400.500', 'D12.125.072.050.875.130.500'], ['A18.400'], ['B01.650.560'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concurrent inhibition of PI3-kinase and mTOR induces cell death in diffuse large B cell lymphomas, a mechanism involving down regulation of Mcl-1. | Phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling is frequently dysregulated in diffuse large B cell lymphoma (DLBCL) including the favorable germinal centre B-cell (GCB) and the unfavorable activated B-cell (ABC) subtypes. mTOR promotes cap-dependent translation of proteins, like ... | ['Adaptor Proteins, Signal Transducing', 'Cell Cycle Checkpoints', 'Cell Cycle Proteins', 'Cell Death', 'Cell Line, Tumor', 'Everolimus', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Imidazoles', 'Lymphoma, Large B-Cell, Diffuse', 'Myeloid Cell Leukemia Sequence 1 Protein', 'NF-kappa B', 'Phosphatidylinositol 3... | 23,200,668 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G04.144.109'], ['D12.776.167'], ['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.540.505.760.500'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['C04.557.386.480.150.585', 'C15.604.515.569.480.150.585', 'C... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. | Sunlight is a carcinogen to which everyone is exposed. Its UV component is the major epidemiologic risk factor for squamous cell carcinoma of the skin. Of the multiple steps in tumor progression, those that are sunlight-related would be revealed if they contained mutations specific to UV. In a series of New England and... | ['Aged', 'Amino Acid Sequence', 'Base Sequence', 'Carcinoma, Squamous Cell', 'Exons', 'Female', 'Genes, p53', 'Humans', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Neoplasms, Radiation-Induced', 'Oligodeoxyribonucleotides', 'Polymerase Chain Reaction', 'Skin Neoplasms', 'Sunlight', 'Tumor Suppressor Protein p53'... | 1,946,433 | [['M01.060.116.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Studies on the mechanisms of action of disopyramide on insulin secretion. The modification by high glucose solution]. | Using the islet perifusion preparation and the isolated rat pancreas in situ perfusion preparation, the effects of disopyramide (Diso) on insulin secretion were studied. In an isolated pancreatic islet perifusion experiment, Diso (300 micrograms/ml) produced a significant increase in the immunoreactive insulin (IRI) le... | ['Animals', 'Disopyramide', 'Drug Interactions', 'Glucose Solution, Hypertonic', 'In Vitro Techniques', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Male', 'Rats', 'Rats, Inbred Strains'] | 2,184,170 | [['B01.050'], ['D03.383.725.227'], ['G07.690.773.968'], ['D26.776.314.420'], ['E05.481'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', 'A06.300.414'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Carbon nanotubes as structural nanofibers for hyaluronic acid hydrogel scaffolds. | We have successfully dispersed functionalized single-walled carbon nanotubes (SWNTs) within hyaluronic acid-water solutions. Hybrid hyaluronic acid (HA) hydrogels with SWNTs were then formed by cross-linking with divinyl sulfone. We have found a considerable change in the morphology of the lyophilized hybrid hydrogels ... | ['Hyaluronic Acid', 'Hydrogels', 'Nanotubes, Carbon', 'Tissue Engineering', 'Tissue Scaffolds'] | 18,186,607 | [['D09.698.373.475'], ['D20.280.320.375', 'D26.255.165.320.375'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['E05.481.500.311.500', 'J01.293.069.249.500'], ['E07.206.627', 'E07.695.825']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Lymphoma: a pediatrician's perspective. | Since Thomas Hodgkin's paper, entitled "On Some Morbid Appearances of the Absorbent Glands and Spleen", published in 1832, an enormous body of research on lymphomas has developed. Even more research is required, however, in order to completely prevent or treat these neoplasms of the lymphocytes. | ['Adolescent', 'Humans', 'Lymphocytes', 'Lymphoma', 'Pediatrics'] | 20,223,710 | [['M01.060.057'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['H02.403.670']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
A comparative study of doxazosin versus atenolol in mild-to-moderate hypertension. | Doxazosin, a quinazoline derivative, is a selective alpha 1-inhibitor that reduces calculated coronary heart disease risk by lowering blood pressure while favorably affecting blood lipid levels. The aim of this study was to compare the efficacy and toleration of doxazosin with atenolol, one of the most frequently used ... | ['Adolescent', 'Adrenergic alpha-Antagonists', 'Adult', 'Aged', 'Antihypertensive Agents', 'Atenolol', 'Doxazosin', 'Electrocardiography', 'Female', 'Humans', 'Hypertension', 'Lipids', 'Male', 'Middle Aged', 'Prazosin'] | 2,904,754 | [['M01.060.057'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.411.162'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['D03.633.100.786.750.200'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genistein inhibited proliferation and induced apoptosis in acute lymphoblastic leukemia, lymphoma and multiple myeloma cells in vitro. | Genistein is one of the major isoflavones in soy products. It has been reported that genistein has apoptotic effects on certain hematological malignancies. However, so far there have been no completely comparative studies of the effect of genistein on malignant hematological diseases, especially multiple myeloma. We in... | ['Antineoplastic Agents', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Genistein', 'Humans', 'Lymphoma', 'Multiple Myeloma', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma'] | 21,749,310 | [['D27.505.954.248'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.383.663.283.266.450.400.375', 'D03.633.100.150.266.450.400.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.60... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The results of using a new surgical method in carcinomas located in the proximal portion of the lower third of the rectum]. | A new type of abdomino-transanal resection of the rectum instead of its extirpation is being applied in tumors localized in the proximal part of the lower one third of rectum (5-6 cm from the anorectal line). For removing the whole lymph collector of the lower one third of the rectum the authors remove the levator tunn... | ['Anal Canal', 'Anastomosis, Surgical', 'Carcinoma', 'Colon, Sigmoid', 'Colostomy', 'Humans', 'Rectal Neoplasms', 'Rectum', 'Suture Techniques'] | 2,097,436 | [['A03.556.124.526.070', 'A03.556.249.249.070'], ['E04.035'], ['C04.557.470.200'], ['A03.556.124.526.356.668', 'A03.556.249.249.356.668'], ['E04.210.338.225', 'E04.579.338.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.4... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age- and Functional Status-Dependent Association Between Blood Pressure and Cognition: The Milan Geriatrics 75+ Cohort Study. | OBJECTIVES: To evaluate whether the relationship between blood pressure (BP) measures and cognitive function is different according to age and functional status in older outpatients.DESIGN: Cross-sectional.SETTING: Outpatient hospital-based Milan Geriatrics 75+ Cohort Study.PARTICIPANTS: Individuals aged 75 and older (... | ['Activities of Daily Living', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Blood Pressure', 'Blood Pressure Determination', 'Cognition', 'Cohort Studies', 'Cross-Sectional Studies', 'Female', 'Geriatric Assessment', 'Humans', 'Male'] | 26,280,562 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['F02.463.188'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.85... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Dispersing carbon nanotubes by chiral network surfactants. | Chiral network surfactants (CNSs) possessing miscibility with carbon nanotubes (CNTs) and chiral materials are applied to disperse CNTs. Ultraviolet-visible absorption spectroscopy is used to quantitatively determine the CNT concentration in homogeneous CNT-CNS dispersions, results indicate that CNSs with more mole fra... | ['Liquid Crystals', 'Nanotubes, Carbon', 'Surface-Active Agents', 'Temperature'] | 25,789,867 | [['J01.637.506'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['D27.720.877'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Routes of lymphatic drainage from the pancreas: a suggested segmentation. | The peripancreatic lymphatics were dissected after intrapancreatic injections of different colorants by territory. The aim of this study was partly to determine the lymphatic drainage routes specific to each pancreatic segment, and partly to define the nodal relay stations for each territory. Whatever the site of injec... | ['Humans', 'In Vitro Techniques', 'Lymphatic System', 'Pancreas'] | 1,589,845 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A15.382.520'], ['A03.734']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aortic root complications of infective endocarditis--influence on surgical outcome. | Fifty cases of aortic valve endocarditis during a 6-year period between 1982 and 1988 were reviewed. Twenty-three (46%) had aortic root complications by way of aortic root abscess or mycotic aneurysm in the perivalvular area. Patients with root complications were grouped into the aortic root abscess (ARA) group and tho... | ['Abscess', 'Adult', 'Aged', 'Aged, 80 and over', 'Aneurysm, Infected', 'Aorta, Thoracic', 'Aortic Aneurysm', 'Aortic Valve', 'Aortitis', 'Endocarditis, Bacterial', 'Female', 'Follow-Up Studies', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Postoperative Complications', 'Reoperation', 'St... | 2,044,559 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.069', 'C14.907.055.131'], ['A07.015.114.056.372'], ['C14.907.055.239', 'C14.907.109.139'], ['A07.541.510.110'], ['C14.907.109.320', 'C14.907.940.080'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Flunarizine shows increased antiepileptic efficacy with elevated K+ levels in low magnesium induced epileptic activity (neocortical slices, guinea pig). | Organic calcium channel blockers have been demonstrated to abolish epileptic activity in various experimental models. Furthermore, it was shown that the antiepileptic efficacy of the organic calcium channel blocker verapamil was significantly augmented when the KCl concentration background was elevated to levels normal... | ['Animals', 'Anticonvulsants', 'Cerebral Cortex', 'Electroencephalography', 'Epilepsy', 'Evoked Potentials', 'Flunarizine', 'Guinea Pigs', 'In Vitro Techniques', 'Magnesium Deficiency', 'Potassium'] | 7,936,095 | [['B01.050'], ['D27.505.954.427.080'], ['A08.186.211.200.885.287.500'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['G07.265.216.500', 'G11.561.200.500'], ['D03.383.606.450'], ['B01.050.150.900.649.313.992.550'], ['E05.481'], ['C18.654.521.500.439'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrophysiological evidence of statistical learning of long-distance dependencies in 8-month-old preterm and full-term infants. | Using electroencephalography, we examined 8-month-old infants' ability to discover a systematic dependency between the first and third syllables of successive words, concatenated into a monotonous speech stream, and to subsequently generalize this regularity to new items presented in isolation. Full-term and preterm in... | ['Child Development', 'Electroencephalography', 'Electrophysiology', 'Female', 'Humans', 'Infant', 'Infant, Premature', 'Language', 'Learning', 'Linguistics', 'Male', 'Speech Perception'] | 25,865,749 | [['F01.525.200', 'G07.345.374.750'], ['E01.370.376.300', 'E01.370.405.245'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520.520'], ['F01.145.209.399', 'L01.559'], ['F02.463.425', 'F02.784.629.529'], ['L01.559.598'], ['F02.463.593.071.875', 'G0... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Role of capsular sialic acid in virulence and resistance to phagocytosis of Streptococcus suis capsular type 2. | Streptococcus suis capsular type 2 has a capsule rich in sialic acid (NANA). Sialic acid, known to be an antiphagocytic factor for many bacterial species, inhibits the activation of the alternative complement pathway. The role of capsular NANA in virulence, resistance to phagocytosis and intracellular survival of S. su... | ['Animals', 'Bacterial Capsules', 'Humans', 'In Vitro Techniques', 'Microscopy, Electron', 'Monocytes', 'N-Acetylneuraminic Acid', 'Phagocytosis', 'Polysaccharides, Bacterial', 'Streptococcal Infections', 'Streptococcus suis', 'Swine', 'Swine Diseases', 'Virulence'] | 8,856,318 | [['B01.050'], ['A20.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E01.370.350.515.402', 'E05.595.402'], ['A11.118.637.555.652', 'A11.148.580', 'A11.627.624', 'A11.733.547', 'A15.145.229.637.555.652', 'A15.378.316.580', 'A15.382.490.555.652', 'A15.382.670.547', 'A15.382.680.547'], ['D02.241.081.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of cytidine diphosphate choline (CDP-choline) on ischemia-induced alterations of brain lipid in the gerbil. | Brain ischemia was produced in gerbils (Meriones unguiculatus) by the bilateral ligation of the carotid arteries. Definite changes in the energy status of brain demonstrated that carotid occlusion was effective. Five minutes before ligation, an intraventricular injection of either saline or cytidine disphosphate cholin... | ['Animals', 'Arachidonic Acid', 'Arachidonic Acids', 'Brain', 'Carotid Arteries', 'Choline', 'Cytidine Diphosphate Choline', 'Diglycerides', 'Fatty Acids, Nonesterified', 'Gerbillinae', 'Ischemia', 'Lipid Metabolism', 'Phosphatidylcholines'] | 6,796,897 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['A08.186.211'], ['A07.015.114.186'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D02.092.877.883.333.130', 'D02.675.276.232.130', 'D03.383.742.686.246.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Eosinophilic Enteritis in Horses with Motor Neuron Disease. | BACKGROUND: Equine motor neuron disease (EMND) is a neuromuscular disorder that affects adult horses. Although EMND has been linked to vitamin E deficiency, its etiopathogenesis is poorly understood.OBJECTIVES: To describe clinical features, laboratory results, and postmortem findings in a series of young horses with m... | ['Animal Feed', 'Animals', 'Diet', 'Enteritis', 'Eosinophilia', 'Female', 'Gastritis', 'Horse Diseases', 'Horses', 'Male', 'Motor Neuron Disease', 'Muscular Atrophy', 'Protozoan Infections, Animal', 'Vitamin E'] | 27,015,868 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G07.203.650.240'], ['C06.405.205.462', 'C06.405.469.326'], ['C15.378.553.231'], ['C06.405.205.697', 'C06.405.748.398'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C10.574.562', 'C10.668.467'], ['C10.597.613.612', 'C23.300.070.500', 'C23.888.592.60... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Global Genome Biodiversity Network: saving a blueprint of the Tree of Life - a botanical perspective. | BACKGROUND: Genomic research depends upon access to DNA or tissue collected and preserved according to high-quality standards. At present, the collections in most natural history museums do not sufficiently address these standards, making them often hard or impossible to use for whole-genome sequencing or transcriptomi... | ['Biodiversity', 'Conservation of Natural Resources', 'Ecosystem', 'Gardens', 'Genomics', 'Humans', 'Pilot Projects', 'Plants'] | 27,328,683 | [['G16.500.275.157.049', 'N06.230.124.049'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['J01.040.415', 'J03.320'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['B0... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Concordance of Pharmacist Assessment of Medication Nonadherence With a Self-Report Medication Adherence Scale. | OBJECTIVE: To evaluate the concordance of the Modified Morisky Scale (MMS) with a pharmacist assessment of medication adherence during a medication review.METHODS: This retrospective study examined the electronic medical records (EMRs) of patients ?18 years who received a medication review by a pharmacist from October ... | ['Adult', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Medication Adherence', 'Medication Reconciliation', 'Middle Aged', 'Pharmacists', 'Professional Role', 'Retrospective Studies', 'Self Report'] | 25,312,260 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.600.500', 'F01.145.488.887.500.600.500', 'N05.300.150.800.500.600.500'], ['E02.319.529.500', 'N02.421.450.500.500', 'N04.452.528.460', 'N04.590.656'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Hypermethylation of CpG island of DLC-1 gene and arsenic trioxide-induced DLC-1 gene demethylation in multiple myeloma]. | OBJECTIVE: To explore the role of hypemethylation of DLC-1 gene in the pathogenesis of multiple myeloma (MM) and examine the effects of arsenic trioxide (As(2)O(3))-induced demethylation of DLC-1 gene in U266 cell line.METHODS: The methylation status of DLC-1 gene was detected by methylation specific PCR (MSP) in MM pa... | ['Arsenic Trioxide', 'Arsenicals', 'Cell Line, Tumor', 'CpG Islands', 'DNA Methylation', 'GTPase-Activating Proteins', 'Humans', 'Multiple Myeloma', 'Oxides', 'RNA, Messenger', 'Tumor Suppressor Proteins'] | 25,534,098 | [['D01.075.038', 'D01.650.550.125'], ['D01.075', 'D02.129'], ['A11.251.210.190', 'A11.251.860.180'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D12.644.360.325.150', 'D12.776.476.325.150'], ['B01.050.150.900.649.313.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Melatonin attenuates osteosarcoma cell invasion by suppression of C-C motif chemokine ligand 24 through inhibition of the c-Jun N-terminal kinase pathway. | Osteosarcoma, with its high metastatic potential, is the most prevalent malignant bone tumor in children and adolescents. Melatonin possesses multiple tumor-suppressing properties for a myriad of tumors, but little is known about the effects of melatonin on osteosarcoma metastasis. In this study, we demonstrated that m... | ['Adolescent', 'Bone Neoplasms', 'Cell Line, Tumor', 'Cell Movement', 'Chemokine CCL24', 'Female', 'Humans', 'Melatonin', 'Mitogen-Activated Protein Kinase 8', 'Mitogen-Activated Protein Kinase 9', 'Neoplasm Invasiveness', 'Neoplasm Proteins', 'Osteosarcoma'] | 29,766,567 | [['M01.060.057'], ['C04.588.149', 'C05.116.231'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['D12.644.276.374.200.110.910', 'D12.776.467.374.200.110.910', 'D23.125.300.110.910', 'D23.469.200.110.910', 'D23.529.374.200.110.910'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.10... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Metabolic handling of 13C labelled tripalmitin in healthy controls and patients with cystic fibrosis. | AIM: To examine the gastrointestinal handling and metabolic disposal of emulsified [1-13C]palmitic acid esterified into a triglyceride in nine healthy children and seven patients with cystic fibrosis on enzyme replacement treatment.METHODS: After an overnight fast, each child was given 10 mg/kg body weight [1,1,1-13C]t... | ['Breath Tests', 'Carbon Isotopes', 'Child', 'Child, Preschool', 'Cystic Fibrosis', 'Digestive System', 'Feces', 'Female', 'Humans', 'Intestinal Absorption', 'Lipase', 'Male', 'Mass Spectrometry', 'Triglycerides'] | 9,771,251 | [['E01.370.100'], ['D01.268.150.075', 'D01.496.123'], ['M01.060.406'], ['M01.060.406.448'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['A03'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Outcome of patients with congestive heart failure treated with standard versus high doses of enalapril: a multicenter study. High Enalapril Dose Study Group. | OBJECTIVES: We sought to prospectively and randomly compare survival with clinical and hemodynamic variables in patients with congestive heart failure (CHF) treated with standard versus high doses of enalapril.BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors produce hemodynamic and symptomatic benefits in pat... | ['Adolescent', 'Adult', 'Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Enalapril', 'Female', 'Heart Failure', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Survival Analysis', 'Treatment Outcome'] | 11,127,445 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.389.745.085'], ['D12.644.456.345.360'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['E01.789.800', 'N04.761.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of the different doses of acrylamide on acetylocholinoesterase activity, thiol groups, malondialdehyde concentrations in hypothalamus and selected muscles of mice. | Acrylamide is a chemical compound that typically forms in starchy food products during high-temperature cooking, including frying, baking and roasting. Acrylamide is a known lethal neurotoxin. Its discovery in some cooked starchy foods in 2002 prompted concerns about the carcinogenicity of those foods. Little is known ... | ['Acetylcholinesterase', 'Acrylamide', 'Animals', 'Hot Temperature', 'Hypothalamus', 'Male', 'Malondialdehyde', 'Mice', 'Muscles', 'Oxidative Stress'] | 29,151,073 | [['D08.811.277.352.100.170.176'], ['D02.065.122.015', 'D02.241.081.069.094.015'], ['B01.050'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D02.047.700'], ['B01.050.150.900.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relationships between cellular superoxide dismutase and susceptibility to chemically induced cancer in the rat mammary gland. | Increasing evidence suggests a role for reactive free radical oxygen species in the multi-stage events of chemical carcinogenesis. We hypothesized that variations in the level of superoxide dismutase (SOD), a major endogenous antioxidant enzyme, may account in part for variations in susceptibility to cancer induced by ... | ['9,10-Dimethyl-1,2-benzanthracene', 'Age Factors', 'Animals', 'Copper', 'Female', 'Mammary Glands, Animal', 'Mammary Neoplasms, Experimental', 'Manganese', 'Polycyclic Compounds', 'Pregnancy', 'Rats', 'Rats, Inbred Strains', 'Superoxide Dismutase'] | 3,087,649 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['A10.336.482', 'A13.589'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['D04'], ... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relative accuracy of the BD Logic and FreeStyle blood glucose meters. | BACKGROUND: The BD Logic((R)) (Becton, Dickinson and Co., Franklin Lakes, NJ) and FreeStyle((R)) (Abbott Diabetes Care, Alameda, CA) meters are used to transmit data directly to insulin pumps for calculation of insulin doses and to calibrate continuous glucose sensors as well as to monitor blood glucose levels.METHODS:... | ['Blood Glucose', 'Capillaries', 'Child', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Inpatients', 'Insulin Infusion Systems', 'Male', 'Monitoring, Physiologic', 'Reproducibility of Results', 'Veins'] | 17,425,442 | [['D09.947.875.359.448.500'], ['A07.015.461.165'], ['M01.060.406'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['E02.319.300.508', 'E07.505.508', 'E07.858.082.505.508'], ['E01.370.520'], ['E05.318.37... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Twenty-four-hour heart preservation using continuous cold perfusion and copper (II) complexes. | BACKGROUND: During long-term in vitro heart preservation and subsequent reperfusion, irreversible tissue damage occurs in part due to reactive oxygen species. Therefore, inhibition of generation of oxygen-derived free radicals and the related oxidative damage of ischemic tissue may be useful in maintaining heart functi... | ['Animals', 'Antioxidants', 'Aspirin', 'Cold Temperature', 'Copper', 'Creatine Kinase', 'Heart', 'In Vitro Techniques', 'Lipid Peroxidation', 'Malondialdehyde', 'Myocardial Reperfusion Injury', 'Organ Preservation', 'Perfusion', 'Rats', 'Rats, Inbred SHR', 'Reactive Oxygen Species', 'Solutions', 'Superoxide Dismutase',... | 9,878,309 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.657.410.595.176'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D08.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Trichloramine Removal with Activated Carbon Is Governed by Two Reductive Reactions: A Theoretical Approach with Diffusion-Reaction Models. | Mechanisms underlying trichloramine removal with activated carbon treatment were proven by batch experiments and theoretical analysis with diffusion-reaction models. The observed values of trichloramine and free chlorine were explained only by the model in which (1) both trichloramine and free chlorine were involved as... | ['Adsorption', 'Charcoal', 'Chlorine', 'Diffusion', 'Kinetics', 'Models, Theoretical'] | 28,355,057 | [['G01.030', 'G02.020'], ['D01.268.150.150'], ['D01.268.380.150', 'D01.362.225'], ['G01.202', 'G02.196'], ['G01.374.661', 'G02.111.490'], ['E05.599']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solvent effects on infrared spectra of methyl 4-hydroxybenzoate in pure organic solvents and in ethanol/CCl4 binary solvents. | Infrared spectroscopy studies of methyl 4-hydroxybenzoate (MHB) in 17 different organic solvents and in ethanol/CCl4 binary solvent were undertaken to investigate the solvent-solute interactions. The frequencies of carbonyl stretching vibration nu(C=O) of MHB in single solvents were correlated with the solvent acceptor... | ['Alcohols', 'Carbon Tetrachloride', 'Ethanol', 'Hydrogen Bonding', 'Parabens', 'Solvents', 'Spectroscopy, Fourier Transform Infrared'] | 15,147,687 | [['D02.033'], ['D02.455.526.439.150'], ['D02.033.375'], ['G02.282'], ['D02.241.223.100.300.460', 'D02.241.511.390.460', 'D02.455.426.559.389.127.281.460', 'D02.455.426.559.389.657.410.460'], ['D27.720.844'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonconvulsive Seizure Detection by Reduced-Lead Electroencephalography in Children with Altered Mental Status in the Emergency Department. | OBJECTIVES: To evaluate the proportion of children presenting to the emergency department (ED) with altered mental status who demonstrate nonconvulsive seizures on reduced-lead electroencephalography (EEG), and to further investigate the characteristics, treatment, and outcomes in these patients compared with patients ... | ['Child, Preschool', 'Electroencephalography', 'Epilepsy, Generalized', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infant', 'Intensive Care Units, Pediatric', 'Japan', 'Mental Health', 'Mental Status Schedule', 'Retrospective Studies', 'Survival Rate'] | 30,528,574 | [['M01.060.406.448'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Strategy and analysis of early management on ninety multiple trauma patients]. | OBJECTIVE: To explore the therapeutical effects through investigating the results of multiple traumas treated by means of damage control surgery (DCS) or early total care (ETC).METHODS: The clinical data of 90 patients with severe multiple traumas admitted from June 2001 to June 2007 were analyzed retrospectively. Fort... | ['Female', 'Humans', 'Injury Severity Score', 'Male', 'Multiple Trauma', 'Treatment Outcome'] | 20,092,743 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N05.715.360.300.715.500.800.400'], ['C26.640'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Queen control over reproductive decisions--no sexual deception in the ant Lasius niger. | Queen-worker conflicts in social insect societies have received much attention in the past decade. In many species workers modify the colony sex ratio to their own advantage or produce their own male offspring. In some other species, however, queens seem to be able to prevent workers from making selfish reproductive de... | ['Animals', 'Ants', 'Body Weights and Measures', 'Deception', 'Female', 'Male', 'Models, Biological', 'Sex Ratio', 'Sexual Behavior, Animal', 'Social Dominance', 'Switzerland', 'Time Factors'] | 12,755,886 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['F01.145.813.157'], ['E05.599.395'], ['G05.815', 'I01.240.800.815', 'N01.224.803.815', 'N06.850.505.400.850.815'], ['F01.145.113.252.748'], ['F01.145.813.650'], ['Z01.542.883'], ['G01.910.857']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
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