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Lateralizing value of postictal automatisms in temporal lobe epilepsy. | PURPOSE: To describe clinical characteristics and lateralizing value of postictal automatisms in patients with temporal lobe epilepsy (TLE).METHODS: One hundred and ninety-three videotaped seizures of 55 consecutive patients with refractory TLE and postoperatively seizure-free outcome were analyzed. Ictal as well as po... | ['Adolescent', 'Adult', 'Age of Onset', 'Automatism', 'Child', 'Epilepsy, Temporal Lobe', 'Functional Laterality', 'Humans', 'Middle Aged', 'Retrospective Studies', 'Seizures', 'Video Recording'] | 16,765,567 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['F02.463.425.179.149'], ['M01.060.406'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', '... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Targeting the HDAC2/HNF-4A/miR-101b/AMPK Pathway Rescues Tauopathy and Dendritic Abnormalities in Alzheimer's Disease. | Histone deacetylase 2 (HDAC2) plays a major role in the epigenetic regulation of gene expression. Previous studies have shown that HDAC2 expression is strongly increased in Alzheimer's disease (AD), a major neurodegenerative disorder and the most common form of dementia. Moreover, previous studies have linked HDAC2 to ... | ['AMP-Activated Protein Kinases', 'Alzheimer Disease', 'Animals', 'Binding Sites', 'Consensus Sequence', 'Dendrites', 'Disease Models, Animal', 'Gene Expression', 'Gene Expression Regulation', 'Gene Silencing', 'Hepatocyte Nuclear Factor 4', 'Histone Deacetylase 2', 'Memory Disorders', 'Mice', 'MicroRNAs', 'Phosphoryla... | 28,202,389 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['B01.050'], ['G02.111.570.120'], ['G02.111.570.580.175'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.297'], ['G05.308']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles. | Nanoparticles have received a great deal of attention for producing new engineering applications due to their novel physicochemical characteristics. However, the broad application of nanomaterials has also produced concern for nanoparticle toxicity due to increased exposure from large-scale industry production. This st... | ['3,4-Dihydroxyphenylacetic Acid', 'Animals', 'Calcium-Binding Proteins', 'Catechol O-Methyltransferase', 'Copper', 'Dopamine', 'Gene Expression Regulation', 'Glutathione Peroxidase', 'Glutathione Synthase', 'Homovanillic Acid', 'Laser-Doppler Flowmetry', 'Manganese', 'Membrane Proteins', 'Metal Nanoparticles', 'Micros... | 19,781,568 | [['D02.241.223.601.220'], ['B01.050'], ['D12.776.157.125'], ['D08.811.913.555.500.250'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G05.308'], ['D08.811.682.732.500'], ['D08.811.464.259.850.500'], ['D02.241.223.601.521'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Derivatives of dexanabinol. II. Salts of amino acid esters containing tertiary and quaternary heterocyclic nitrogen with increased water-solubility. | PURPOSE: Amino acid esters containing tertiary or quaternary nitrogen heterocycles were synthesized for dexanabinol (1) and evaluated as water-soluble prodrugs or congeners.METHODS: Syntheses were performed by conventional methods; stability studies in water, blood (rat, dog, human) and assay-media were performed by HP... | ['Animals', 'Binding, Competitive', 'Cells, Cultured', 'Dizocilpine Maleate', 'Dogs', 'Dronabinol', 'Drug Stability', 'Excitatory Amino Acid Antagonists', 'Humans', 'Hydrolysis', 'Morpholines', 'Nervous System Diseases', 'Neurons', 'Neuroprotective Agents', 'Piperazines', 'Prodrugs', 'Rats', 'Rats, Sprague-Dawley', 'Re... | 8,692,744 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.251'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.455.849.090.810'], ['E05.916.330'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['B01.050.150.900.649.313.988.400.1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synchronous pancreatic tumors in a patient with history of Wilms tumor: A case of pancreatic adenocarcinoma and lipid-rich neuroendocrine tumor diagnosed by cytopathology. | Synchronous tumors represent a very small portion of pancreatic tumors. Although there is a higher incidence of secondary malignant neoplasms (SMN) in patients with history of Wilms tumor (WT), pancreatic tumors are very infrequent SMNs in this population. We report the first case of synchronous pancreatic tumors in a ... | ['Adenocarcinoma', 'Cytodiagnosis', 'Humans', 'Lipids', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Neuroendocrine Tumors', 'Pancreatic Neoplasms', 'Tomography, X-Ray Computed', 'Wilms Tumor'] | 30,194,916 | [['C04.557.470.200.025'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['M01.060.116.630'], ['C04.651'], ['C04.557.465.625.650', 'C04.557.580.625.650'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['E01.370.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A widespread morphological antipredator mechanism reduces the sensitivity to pesticides and increases the susceptibility to warming. | Pollution and predation are two omnipresent stressors in aquatic systems that can interact in multiple ways, thereby challenging accurate assessment of the effects of pollutants in natural systems. Despite the widespread occurrence of morphological antipredator mechanisms, no studies have tested how these can affect th... | ['Animals', 'Chlorpyrifos', 'Food Chain', 'Global Warming', 'Odonata', 'Pesticides', 'Predatory Behavior', 'Water Pollutants, Chemical'] | 29,898,530 | [['B01.050'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['G16.500.275.157.250', 'N06.230.124.250'], ['G16.500.175.374.500'], ['B01.050.500.131.617.720.750.750'], ['D27.720.031.700', 'D27.888.723'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Differential sensitivity in vivo of lethal and nonlethal malarial parasites to endotoxin-induced serum factor. | Sera from mice infected with Plasmodium yoelii or Plasmodium berghei and given endotoxin contained nonspecific mediators which killed both species of parasite and tumor cells in vitro. The sera resembled tumor necrosis sera obtained from mice given macrophage-activating agents such as Propionibacterium acnes (formerly ... | ['Animals', 'Cell Survival', 'Endotoxins', 'Female', 'Glycoproteins', 'L Cells', 'Lipopolysaccharides', 'Macrophage Activation', 'Malaria', 'Mice', 'Plasmodium', 'Plasmodium berghei', 'Tumor Necrosis Factor-alpha'] | 6,752,029 | [['B01.050'], ['G04.346'], ['D23.946.123.329'], ['D09.400.430', 'D12.776.395'], ['A11.251.210.505', 'A11.329.228.505'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['G12.287.500'], ['C01.610.752.530', 'C01.920.875'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.043... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrical impedance tomography for real-time and label-free cellular viability assays of 3D tumour spheroids. | There is currently a need to culture cells in 3D to better mimic the behaviour of cells growing in the natural environment. In parallel, this calls for novel technologies to assess cell growth in 3D cell culture. In this study, we demonstrated both in silico and in vitro that cell viability inside large cell spheroids ... | ['Cell Culture Techniques', 'Electric Impedance', 'Humans', 'Image Processing, Computer-Assisted', 'MCF-7 Cells', 'Neoplasms', 'Spheroids, Cellular', 'Tomography'] | 30,070,264 | [['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G01.358.500.249.277.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A11.251.210.190.630'], ['C04'], ['A11.251.800'], ['E01.370.350.825']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mortality in the elderly: A socio-spatial analysis based on the degree of social deprivation | Background: Mortality in Mexico has decreased substantially in the last years; however, there are segments of the population that experience social deprivation.Objective: To identify and describe at the national level the causes of death by degree of social deprivation (DSD), age and sex.Methods: We analyzed variables ... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Cause of Death', 'Cultural Deprivation', 'Female', 'Humans', 'Male', 'Mexico', 'Middle Aged', 'Sex Factors', 'Social Determinants of Health', 'Socioeconomic Factors'] | 30,777,412 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['I01.880.853.100.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.589'], ['M01.060.116.630'], ['N... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Heterologous Antibodies Adsorption in Xenotransplantation of a Landrace Piglet Kidney Into a Rhesus Monkey. | BACKGROUND: To explore the adsorption of heterologous antibodies in 6 xenotransplants of Landrace piglet kidneys into rhesus monkeys.METHODS: The Landrace piglets and rhesus monkeys were used as donors and recipients, respectively. The donor kidney was the left kidney excised from each Landrace piglet and lavaged with ... | ['Adenosine', 'Adsorption', 'Allopurinol', 'Animals', 'Antibodies, Heterophile', 'Disease Models, Animal', 'Female', 'Glutathione', 'Graft Rejection', 'Insulin', 'Kidney', 'Kidney Transplantation', 'Macaca mulatta', 'Organ Preservation Solutions', 'Raffinose', 'Swine', 'Tissue Donors', 'Transplantation, Heterologous'] | 30,979,492 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['G01.030', 'G02.020'], ['D03.633.100.759.160'], ['B01.050'], ['D12.776.124.486.485.114.191', 'D12.776.124.790.651.114.191', 'D12.776.377.715.548.114.191'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.456.448'], ['G12.875.545.328'], ['D06.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hairpins in a Haystack: recognizing microRNA precursors in comparative genomics data. | UNLABELLED: Recently, genome-wide surveys for non-coding RNAs have provided evidence for tens of thousands of previously undescribed evolutionary conserved RNAs with distinctive secondary structures. The annotation of these putative ncRNAs, however, remains a difficult problem. Here we describe an SVM-based approach th... | ['Algorithms', 'Animals', 'Artificial Intelligence', 'Base Sequence', 'Chromosome Mapping', 'Conserved Sequence', 'Databases, Genetic', 'Genomics', 'Humans', 'Information Storage and Retrieval', 'MicroRNAs', 'Molecular Sequence Data', 'Pattern Recognition, Automated', 'RNA Precursors', 'Sequence Alignment', 'Sequence A... | 16,873,472 | [['G17.035', 'L01.224.050'], ['B01.050'], ['G17.035.250', 'L01.224.050.375'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['G02.111.570.580'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Chronic pain experience on depression and physical disability: The importance of acceptance and mindfulness-based processes in a sample with rheumatoid arthritis. | The mediating effect of acceptance and mindfulness in the relationship between pain, depression, and physical disability was examined in 55 rheumatoid arthritis patients. Results showed that the relationship between pain and depression was mediated by both nonreact and acceptance. By contrast, the relationship between ... | ['Adult', 'Anxiety Disorders', 'Arthritis, Rheumatoid', 'Behavior', 'Chronic Pain', 'Correlation of Data', 'Cross-Sectional Studies', 'Depressive Disorder', 'Disabled Persons', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mindfulness', 'Models, Psychological', 'Pain Measurement', 'Stress, Psychological', 'Surveys and Qu... | 27,307,417 | [['M01.060.116'], ['F03.080'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['F01.145'], ['C23.888.592.612.274'], ['H01.548.832.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.600.300'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Hydrogenotrophic methanogens of the mammalian gut: Functionally similar, thermodynamically different-A modelling approach. | Methanogenic archaea occupy a functionally important niche in the gut microbial ecosystem of mammals. Our purpose was to quantitatively characterize the dynamics of methanogenesis by integrating microbiology, thermodynamics and mathematical modelling. For that, in vitro growth experiments were performed with pure cultu... | ['Animals', 'Biomass', 'DNA, Archaeal', 'Energy Metabolism', 'Intestines', 'Kinetics', 'Methane', 'Methanobacterium', 'Models, Theoretical', 'RNA, Ribosomal, 16S', 'Ruminants', 'Thermodynamics'] | 31,826,000 | [['B01.050'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D13.444.308.180'], ['G03.295'], ['A03.556.124'], ['G01.374.661', 'G02.111.490'], ['D02.455.326.146.571'], ['B02.200.492.500.500'], ['E05.599'], ['D13.444.735.686.670'], ['B01.050.150.900.649.313.500.380'], ['G01.906']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Speed and convergence properties of gradient algorithms for optimization of IMRT. | Gradient algorithms are the most commonly employed search methods in the routine optimization of IMRT plans. It is well known that local minima can exist for dose-volume-based and biology-based objective functions. The purpose of this paper is to compare the relative speed of different gradient algorithms, to investiga... | ['Algorithms', 'Body Burden', 'Humans', 'Lung Neoplasms', 'Radiometry', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Conformal', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 15,191,303 | [['G17.035', 'L01.224.050'], ['E05.799.638.231', 'N06.850.460.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E05.799'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E02.815.635.700', 'L01.313.500.750.100.710.600.550'], ['E05.318... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Stimulation of oxygen to bioanode for energy recovery from recalcitrant organic matter aniline in microbial fuel cells (MFCs). | The challenge of energy generation from biodegradation of recalcitrant organics in microbial fuel cells (MFCs) is mainly attributed to their persistence to degradation under anaerobic condition in anode chamber of MFCs. In this work, we demonstrated that electricity generation from aniline, a typical recalcitrant organ... | ['Aerobiosis', 'Aniline Compounds', 'Bacteria, Aerobic', 'Biodegradation, Environmental', 'Bioelectric Energy Sources', 'Biofilms', 'Electrodes', 'Electrons', 'Oxygen', 'Sewage'] | 26,043,373 | [['G02.111.017', 'G03.049'], ['D02.092.146'], ['B03.120'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.305.124.150'], ['A20.593', 'G06.120'], ['E07.305.250'], ['G01.249.335', 'G01.358.500.750'], ['D01.268.185.550', 'D01.362.670'], ['D20.944.932.500']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Kinematic gait analysis in dogs with hip dysplasia. | OBJECTIVE: To define alterations of movement in dogs with hip dysplasia by use of noninvasive, 3-dimensional, computer-assisted kinematic gait analysis.DESIGN: Kinematic and force plate data were collected at the trot from clinically normal dogs and from dogs with hip dysplasia.ANIMALS: 12 large adult dogs of various b... | ['Animals', 'Dogs', 'Femur', 'Fourier Analysis', 'Gait', 'Hip Dysplasia, Canine', 'Joints', 'Reference Values', 'Video Recording'] | 8,807,004 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A02.835.232.043.150'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C22.268.485'], ['A02.835.583'], ['E05.978.810'], ['L01.280.960']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Disentangling the complexity of infectious diseases: Time is ripe to improve the first-line statistical toolbox for epidemiologists. | Because many biological processes related to the dynamics of infectious diseases are caused by complex interactions between the environment, the host(s) and the agent(s), the necessity to address the methodological implications of this inherent complexity has recently emerged in epidemiology. Most epidemiologists now a... | ['Communicable Diseases', 'Epidemiology', 'Humans', 'Linear Models', 'Models, Statistical'] | 24,035,791 | [['C01.221', 'C23.550.291.531'], ['H02.403.720.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.318.740.500', 'E05.599.835', 'N05.71... | ['Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Use of a virtual immersion computer simulator as a model for basic training in laparoscopic urology]. | BACKGROUND: to date, it has not been defined the best method for teaching urologic laparoscopy, however it is well recognized that it involves a steep learning curve.METHODS: A course of Laparoscopic Urology was done in our Institute. The program included skill practices in a virtual immersion simulator which evaluated... | ['Computer Simulation', 'Computer-Assisted Instruction', 'Laparoscopy', 'Urology', 'User-Computer Interface'] | 17,078,579 | [['L01.224.160'], ['I02.903.771.500.208'], ['E01.370.388.250.520', 'E04.502.250.520'], ['H02.403.810.860'], ['L01.224.900.910']] | ['Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
MiR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesothelioma. | Malignant pleural mesothelioma (MPM) is a rapidly fatal malignancy that is increasing in incidence in Japan. In this study, we performed gene and microRNA (miRNA) expression profiling to identify novel therapeutic targets in MPM cells. Based on relative sensitivities to pemetrexed (PEM) and the histone deacetylase (HDA... | ['Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Proliferation', 'Drug Resistance, Neoplasm', 'Gene Expression', 'Gene Expression Regulation, Neoplastic', 'Glutamates', 'Guanine', 'Humans', 'Hydroxamic Acids', 'Inhibitory Concentration 50', 'Interleukin-18', 'Lung Neoplasms', 'Mesothelioma', 'Mesothelioma, Malignant... | 25,231,602 | [['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.984.395'], ['G05.297'], ['G05.308.370'], ['D12.125.067.625', 'D12.125.119.409'], ['D03.633.100.759.758.399.454'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.570.394', 'D02.241.511.372'], [... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of CYP3A in isoniazid metabolism in vivo. | Isoniazid (INH), a first-line drug for tuberculosis control, frequently causes liver injury. Multiple previous reports suggest that CYP3A is involved in INH metabolism, bioactivation and hepatotoxicity, although direct evidence is unavailable. In the current study, wild-type and Cyp3a-null mice were used to determine t... | ['Administration, Oral', 'Animals', 'Antitubercular Agents', 'Biotransformation', 'Chemical and Drug Induced Liver Injury', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 Enzyme System', 'Isoniazid', 'Liver', 'Male', 'Mice, Knockout', 'Microsomes, Liver'] | 24,172,716 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.122.085.255'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', 'D08.811.682.690.708.170.495.500', 'D12.776.422.220.453.860.500'], ['D08.244.453', 'D08.811.682.690.708.170', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical features and management of ameloblastoma of the mandible in children and adolescents. | Thirty cases of ameloblastoma of the mandible in children and adolescents were reviewed. During the period of evaluation, 206 patients with ameloblastoma in the craniofacial region were seen of which 14.6% were in children (under 18 years). The tumour was more prevalent in male (1.5:1). Enucleation with curettage of th... | ['Adolescent', 'Ameloblastoma', 'Bone Transplantation', 'Child', 'Child, Preschool', 'Curettage', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Mandible', 'Mandibular Neoplasms', 'Neoplasm Recurrence, Local', 'Osteogenesis', 'Osteotomy', 'Periosteum', 'Sex Factors'] | 8,818,260 | [['M01.060.057'], ['C04.557.695.065'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['M01.060.406'], ['M01.060.406.448'], ['E04.157'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A02.835.232.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Midazolam sedation for upper gastrointestinal endoscopy in older persons: a randomized, double-blind, placebo-controlled study. | OBJECTIVES: To investigate the benefits and risks of using midazolam for sedation during upper gastrointestinal endoscopic procedures in older persons.DESIGN: Randomized, double-blind, placebo-controlled study.SETTING: A 304-bed geriatric university hospital.PATIENTS: Sixty-five geriatric inpatients (mean age 84 +/- 7)... | ['Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Anti-Anxiety Agents', 'Conscious Sedation', 'Double-Blind Method', 'Female', 'Gastroscopy', 'Hemodynamics', 'Humans', 'Male', 'Midazolam', 'Pain', 'Patient Satisfaction'] | 11,083,314 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['E03.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.372.25... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Plethysmography without venous occlusion for measuring forearm blood flow: comparison with venous occlusive method. | Limb blood flow is widely used as an indicator of the human vascular properties. There are only few non-invasive methods for its measurement such as venous occlusion plethysmography. However, several authors have questioned its validity. The problems appear to be related to the process of venous occlusion. We developed... | ['Adult', 'Algorithms', 'Blood Flow Velocity', 'Female', 'Forearm', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Middle Aged', 'Plethysmography', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Ultrasonography, Doppler, Pulsed'] | 15,383,087 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['M01.060.116.630'], ['E01.370.370.610'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Stent migration following endoscopic suture fixation of esophageal self-expandable metal stents: a systematic review and meta-analysis. | BACKGROUND: Covered self-expandable metal stents (SEMS) are utilized for the management of benign and malignant esophageal conditions; however, covered SEMS are prone to migration. Endoscopic suture fixation may mitigate the migration risk of covered esophageal SEMS. Hence, we conducted a systematic review and meta-ana... | ['Esophageal Achalasia', 'Esophageal Diseases', 'Esophageal Fistula', 'Esophageal Perforation', 'Esophageal Stenosis', 'Esophagoscopy', 'Foreign-Body Migration', 'Humans', 'Self Expandable Metallic Stents', 'Suture Techniques', 'Treatment Outcome'] | 28,726,147 | [['C06.405.117.119.500.432'], ['C06.405.117'], ['C06.267.250', 'C06.405.117.367', 'C23.300.575.185.250'], ['C06.405.117.468', 'C26.348'], ['C06.405.117.544'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'], ['C26.392.500'], ['B01.050.150.900.649.313.988.400.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Results of bronchoprovocation tests with the allergen Erwinia herbicola in persons with occupational exposure to organic dust]. | The study was carried out on 290 males with occupational organic dust exposition. In all bronchoprovocation test with Erwinia herbicola antigen were carried out. A positive test was seen in 16.2% of the studied subjects. Bronchial hyperreactivity to Erwinia herbicola allergen depended on living environs, occupational e... | ['Adult', 'Aged', "Agricultural Workers' Diseases", 'Alveolitis, Extrinsic Allergic', 'Antigens, Bacterial', 'Bronchial Provocation Tests', 'Dust', 'Environmental Monitoring', 'Erwinia', 'Humans', 'Male', 'Middle Aged', 'Occupational Exposure'] | 8,614,672 | [['M01.060.116'], ['M01.060.116.100'], ['C24.080'], ['C08.381.483.125', 'C08.674.055', 'C20.543.480.680.075'], ['D23.050.161'], ['E01.370.386.700.125'], ['D20.633.222'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B03.440.450.425.300', 'B03.660.250.150.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relational database model for DNA mutations and a software program for implementation of the model. | A relational database model for describing DNA mutations is presented. The model was developed in conjunction with the human hprt database and was successful in representing over 1800 hprt mutations. Mutants showing aberrant mRNA splicing can be adequately described using the model, as well as mutants showing more than... | ['Humans', 'Hypoxanthine Phosphoribosyltransferase', 'Information Systems', 'Mutation', 'Software'] | 8,598,829 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.400.725.450'], ['L01.313.500.750.300'], ['G05.365.590'], ['L01.224.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[A clinico-pathological study comparing Henoch-Schonlein purpura nephritis with IgA nephropathy in children]. | OBJECTIVE: Henoch-Schonlein purpura nephritis (HSPN) and IgA nephropathy are very similar in immunopathological changes, and therefore some nephrologists considered that they are substantially one disease entity caused by IgA immune abnormalities, and IgA nephropathy is, in fact, a kind of HSPN without rashes. The pres... | ['Adolescent', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Female', 'Glomerulonephritis, IGA', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Immunologic Tests', 'Male', 'Nephritis', 'Prognosis', 'Purpura, Schoenlein-Henoch'] | 14,728,884 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['C12.777.419.570.363.608', 'C13.351.968.419.570.363.608', 'C20.111.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['D12.776.124.486.48... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessment of mortality by qSOFA in patients with sepsis outside ICU: A post hoc subgroup analysis by the Japanese Association for Acute Medicine Sepsis Registry Study Group. | Quick sequential organ failure assessment (qSOFA) was proposed in the new sepsis definition (Sepsis-3). Although qSOFA was created to identify patients with suspected infection and likely to have poor outcomes, the clinical utility of qSOFA to screen sepsis has not been fully evaluated. We investigated the number of pa... | ['Aged', 'Aged, 80 and over', 'Female', 'Hospital Mortality', 'Humans', 'Hypothermia', 'Japan', 'Male', 'Middle Aged', 'Organ Dysfunction Scores', 'Predictive Value of Tests', 'Prognosis', 'Prospective Studies', 'ROC Curve', 'Registries', 'Retrospective Studies', 'Sepsis', 'Survivors'] | 28,847,586 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.119.565'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['E05.318.308.980.438.475.456.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
CD79 alpha/CD79 beta heterodimers are expressed on pro-B cell surfaces without associated mu heavy chain. | During B cell development, the surface expression of CD79 alpha/CD79 beta heterodimers had been thought to begin in the pre-B cell stage where the heterodimers constitute pre-B cell receptors together with mu heavy and surrogate light chains. Thereafter, in mature B cells, CD79 alpha/CD79 beta associates with surface I... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, CD', 'B-Lymphocytes', 'Bone Marrow Cells', 'CD79 Antigens', 'Cell Line', 'Cell Membrane', 'Dimerization', 'Epitopes', 'Immunoglobulin Heavy Chains', 'Immunoglobulin mu-Chains', 'Mice', 'Receptors, Antigen, B-Cell'] | 9,418,137 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.148', 'A15.378.316'], ['D12.776.124.790.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA-binding protein Pur alpha and transcription factor YY1 function as transcription activators of the neuron-specific FE65 gene promoter. | Fe65 is an adaptor protein that interacts with the Alzheimer beta-amyloid precursor protein and is expressed mainly in the neurons of several regions of the nervous system. The FE65 gene has a TATA-less promoter that drives an efficient transcription in cells showing a neuronal phenotype, whereas its efficiency is poor... | ['Animals', 'CHO Cells', 'Cattle', 'Cricetinae', 'Cyclic AMP Response Element-Binding Protein', 'DNA-Binding Proteins', 'Drug Synergism', 'Erythroid-Specific DNA-Binding Factors', 'Nerve Tissue Proteins', 'Neurons', 'Nuclear Proteins', 'Promoter Regions, Genetic', 'Protein Binding', 'Rats', 'Trans-Activators', 'Transcr... | 9,359,867 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.649.313.992.635.075.250'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D12.776.260'], ['G07.690.773.968.477'], ['D12.776.260.235', 'D12.776.930.216'], ['D12.776.631'], ['A08.675', 'A11.671'], ['D12.776.660... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The chromosomal location of rDNA in selected lower primates. | Hybridization in stiu was used to identify the chromosomes that carry rDNA in representative lower primates, including the baboons, Papio cynocephalus and Papio hamadryas; the colobus monkey, Colobus polykomos; the tree shrew, Tupaia glis; the lemur, Lemur fulvis; the saki, Pithecia pithecia; the marmoset, Saguinus nig... | ['Animals', 'Callitrichinae', 'Cell Line', 'Chromosome Mapping', 'Colobus', 'Haplorhini', 'Karyotyping', 'Lemur', 'Nucleic Acid Hybridization', 'Papio', 'Shrews', 'Species Specificity'] | 414,888 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.150.150'], ['A11.251.210'], ['E05.393.183'], ['B01.050.150.900.649.313.988.400.112.199.150.150'], ['B01.050.150.900.649.313.988.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['B01.050.150.900.649.313.988.700.508.490']... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fifteen-year results of coronary artery bypass for isolated left anterior descending coronary artery disease. | During 1971 through 1975, 266 patients underwent primary coronary artery bypass grafting for occlusive disease confined to the left anterior descending coronary artery. Actuarial survival at 15 years was 72.7% with 60% of survivors being free from angina. Although the cause of death was cardiac related in 50% of the pa... | ['Adult', 'Aged', 'Angina Pectoris', 'Angioplasty, Balloon', 'Cause of Death', 'Coronary Artery Bypass', 'Coronary Disease', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Prognosis', 'Reoperation'] | 2,523,696 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E04.100.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Photosensitive epilepsy in children. | We performed a retrospective analysis of 17 children with photosensitive seizures (PSS) who had been followed for more than 3 years (mean: 9 years). PSS were verified in all patients by simultaneous video-EEG monitoring. The seizures were precipitated by flickering stroboscopes (14 patients) or were induced by patients... | ['Adolescent', 'Adult', 'Anticonvulsants', 'Child', 'Electroencephalography', 'Epilepsies, Myoclonic', 'Epilepsies, Partial', 'Epilepsy', 'Epilepsy, Tonic-Clonic', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Photic Stimulation', 'Treatment Outcome'] | 8,044,456 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.427.080'], ['M01.060.406'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375.130', 'C10.228.140.490.493.063'], ['C10.228.140.490.360'], ['C10.228.140.490'], ['C10.228.140.490.375.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does a national screening programme reduce socioeconomic inequalities in mammography use? | OBJECTIVES: To investigate possible changes in socioeconomic inequalities in mammography use among women aged 50-69 years between the start of the Belgian national screening programme in 2001 and three years later (2004), and to assess if the implementation of an organised screening programme has been successful in red... | ['Aged', 'Belgium', 'Female', 'Forecasting', 'Health Education', 'Health Surveys', 'Humans', 'Mammography', 'Mass Screening', 'Middle Aged', 'Odds Ratio', 'Socioeconomic Factors', 'Utilization Review'] | 19,247,577 | [['M01.060.116.100'], ['Z01.542.115'], ['I01.320'], ['I02.233.332', 'N02.421.726.407'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.... | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Anxiety sensitivity taxonicity across gender among youth. | The present investigation comparatively evaluated the latent class structure and parameters of anxiety sensitivity (AS) among female and male youth using the Childhood Anxiety Sensitivity Index. Participants were 4462 adolescents (2189 females) in grades 7-12 (M(age)=15.6 years). Consistent with prediction, taxometric ... | ['Adolescent', 'Anxiety', 'Data Interpretation, Statistical', 'Disease Susceptibility', 'Female', 'Humans', 'Male', 'Psychometrics', 'Risk Factors', 'Sex Factors'] | 16,098,477 | [['M01.060.057'], ['F01.470.132'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C23.550.291.687', 'G07.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.780'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.70... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Frequent isolation of intertypic poliovirus recombinants with serotype 2 specificity from vaccine-associated polio cases. | Five representatives from a collection of 21 Sabin type 2-like poliovirus strains isolated from paralytic poliomyelitis cases in two regions of the USSR have been subjected to limited nucleotide sequencing. All proved to be intertypic recombinants having the genes encoding capsid proteins of Sabin 2 origin and a 3'-end... | ['Base Sequence', 'Child, Preschool', 'Chromosome Mapping', 'Feces', 'Genome, Viral', 'Humans', 'Infant', 'Molecular Sequence Data', 'Mutagenesis', 'Nucleotide Mapping', 'Poliomyelitis', 'Poliovirus', 'Poliovirus Vaccine, Oral', 'RNA, Viral', 'Recombination, Genetic', 'Serotyping', 'USSR'] | 1,666,406 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.060.406.448'], ['E05.393.183'], ['A12.459'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['L01.453.245.667'], ['G05.558'], ['E05.196.181.400.454.655', 'E05.196.401.319.670', 'E05.196.680'], ['C01.207.618.750... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Simplified endoscopic placement of nasoenteral feeding tubes. | A technique for expeditious and safe placement of nasoenteric feeding tubes under direct vision is described. Adult patients undergo feeding tube placement with intravenous sedation and topical anesthesia. Endoscopic tube placement requires an average of 10 min and eliminates many risks associated with blind passage. | ['Endoscopy', 'Enteral Nutrition', 'Humans', 'Intubation, Gastrointestinal'] | 3,095,170 | [['E01.370.388.250', 'E04.502.250'], ['E02.421.360', 'E02.642.500.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.585.412', 'E05.497.412']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impacts of flow regulation on freshwater pearl mussel (Margaritifera margaritifera) habitat in a Scottish montane river. | The River Moriston in NW Scotland is a cobble-gravel bedded river that has been dammed and regulated for hydroelectric power (HEP) since 1956. The river supports a functional population of the critically endangered freshwater pearl mussel (Margaritifera margaritifera) in the lower part. In contrast the population in th... | ['Animals', 'Conservation of Natural Resources', 'Ecosystem', 'Environment', 'Geographic Information Systems', 'Geologic Sediments', 'Human Activities', 'Humans', 'Pinctada', 'Rivers', 'Scotland', 'Water Movements'] | 22,750,177 | [['B01.050'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275', 'N06.230'], ['L01.313.500.750.300.314', 'L01.470.750.750.462'], ['G01.311.330', 'G16.500.320'], ['I03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.644.080.670'], ['G01.311.750', 'G16.500.275.280.650', 'N06... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
Cytopathology of Hepatobiliary-Related Actinomycosis. | BACKGROUND: The clinical diagnosis of hepatobiliary-related actinomycosis can be challenging owing to its rarity and variable presentation. Moreover, actinomycotic pseudotumors may mimic malignancy and result in unnecessary surgical resection. Herein, we present the clinical and cytopathological features of 3 cases wit... | ['Actinomyces', 'Actinomycosis', 'Aged', 'Aged, 80 and over', 'Bile Ducts', 'Constriction, Pathologic', 'Female', 'Humans', 'Liver', 'Male'] | 27,199,159 | [['B03.510.024.049.050.050', 'B03.510.460.400.400.049.049.178'], ['C01.150.252.410.040.137'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.159.183'], ['C23.300.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620']] | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
S100A8 triggers oxidation-sensitive repulsion of neutrophils. | The inflammatory response to tissue injury is a multi-faceted process. During this process, neutrophils migrate in the extravascular spaces, directed to the site of injury by chemical gradients generated by chemotactic molecules. S100A8, a protein associated with a wide variety of inflammatory conditions, is heavily ov... | ['Alanine', 'Animals', 'Calgranulin A', 'Cells, Cultured', 'Chemotaxis, Leukocyte', 'Cysteine', 'Flow Cytometry', 'Humans', 'Inflammation', 'Inflammation Mediators', 'Lipopolysaccharides', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Oxidation-Reduction', 'Rats', 'Recombinant Proteins'] | 16,931,866 | [['D12.125.042'], ['B01.050'], ['D12.776.157.125.750.500.100', 'D12.776.631.655.500.100', 'D23.050.301.562.100'], ['A11.251'], ['G04.198.424.233'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Online systems complicate I/S capacity planning. | The days are fundamentally gone when healthcare information is posted in batches. Online systems have totally changed the I/S picture. Departments trying to plan for demand have a much harder job of it, but help is available. | ['Data Collection', 'Hospital Departments', 'Hospital Information Systems', 'Online Systems', 'Planning Techniques', 'United States', 'Workload'] | 10,134,532 | [['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N02.278.216.500.968', 'N04.452.442.452.422'], ['N04.452.442.452.452', 'N04.452.515.360'], ['L01.313.500.750.300.742'], ['N04.452.718'], ['Z01.107.567.875'], ['I03.946.225.500', 'N04.452.677.650.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Promoting research integrity in Africa: an African voice of concern on research misconduct and the way forward. | African researchers and their collaborators have been making significant contributions to useful research findings and discoveries in Africa. Despite evidence of scientific misconduct even in heavily regulated research environments, there is little documented information that supports prevalence of research misconduct ... | ['Africa', 'Ethics, Research', 'Humans', 'Research Personnel', 'Scientific Misconduct'] | 23,594,261 | [['Z01.058'], ['K01.752.566.479.173', 'N05.350.670'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.839'], ['K01.752.566.479.915.500', 'N05.350.979.500']] | ['Geographicals [Z]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Role of insulin in food intake, weight gain and lipid deposition in the Zucker obese rat. | The role of insulin status in the development of obesity in Zucker rats was determined by equalization of available insulin. When streptozotocin-induced diabetic obese and lean rats received the same level of exogenous insulin, body weight gain and food intake per body weight were equalized. These types of observations... | ['Animals', 'Body Weight', 'Diabetes Mellitus', 'Diabetes Mellitus, Experimental', 'Diet', 'Female', 'Insulin', 'Lipid Metabolism', 'Obesity', 'Rats', 'Rats, Mutant Strains', 'Rats, Zucker', 'Thinness'] | 7,042,936 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.452.394.750', 'C19.246'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G07.203.650.240'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.458'], ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Late management of the aortic root after repair of tetralogy of Fallot: A European multicentre study. | OBJECTIVES: We sought to determine the indications, type, and outcomes of reoperations on the aortic root after repair of tetralogy of Fallot (TOF).METHODS: Eleven centers belonging to the European Congenital Heart Surgeons Association contributed to the data collection process. We included 36 patients who underwent su... | ['Adult', 'Aorta', 'Aortic Valve', 'Aortic Valve Insufficiency', 'Child', 'Child, Preschool', 'Dilatation, Pathologic', 'Female', 'Follow-Up Studies', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Reoperation', 'Tetralogy of Fallot', 'Time Factors', 'Treatment Outcome'] | 31,899,837 | [['M01.060.116'], ['A07.015.114.056'], ['A07.541.510.110'], ['C14.280.484.048.500'], ['M01.060.406'], ['M01.060.406.448'], ['C23.300.325'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibitory effect of GABAergic drugs in cocaine-induced genital reflexes in paradoxical sleep-deprived male rats. | The aim of this study was to seek whether GABAergic drugs were involved in the action of cocaine on spontaneous genital reflexes (penile erection-PE, and ejaculation-EJ) of paradoxical sleep-deprived (PSD) male rats. After a 4-day period of PSD, each group was administered with GABAergic drugs 1 h prior to cocaine and ... | ['Animals', 'Cocaine', 'Dose-Response Relationship, Drug', 'Ejaculation', 'GABA Agents', 'GABA-A Receptor Agonists', 'GABA-A Receptor Antagonists', 'Male', 'Neural Inhibition', 'Penile Erection', 'Rats', 'Rats, Wistar', 'Receptors, GABA-A', 'Sleep Deprivation'] | 15,219,771 | [['B01.050'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['G07.690.773.875', 'G07.690.936.500'], ['G08.686.784.084'], ['D27.505.519.625.240', 'D27.505.696.577.240'], ['D27.505.519.625.240.200.500', 'D27.505.696.577.240.200.500'], ['D27.505.519.625.240.300.500', 'D27.505.69... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nocturnalism: an ethological theory of schizophrenia. | Schizophrenia is a human behavioral variant with a 1% phenotypic population frequency. As the major "mental illness" affecting human beings, it has defied all previous attempts to explain, predict or prevent its devastating clinical manifestations. In addition to unidentified nongenetic determinants, schizophrenia has ... | ['Adolescent', 'Adult', 'Age Factors', 'Blindness', 'Catatonia', 'Darkness', 'Ethology', 'Heterozygote', 'Humans', 'Memory', 'Narcolepsy', 'Schizophrenia', 'Seasons', 'Sleep', 'Social Isolation'] | 7,155,014 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['C10.597.606.115', 'C23.888.592.604.115', 'F01.145.126.156', 'F01.700.165'], ['G01.590.540.233'], ['F04.096.208'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Religion and spirituality: the perspective of health professionals. | This study examined how health professionals signify the religiosity and faith of patients under cancer treatment and how they themselves experience such phenomena. This is a qualitative-descriptive study, using the phenomenological framework as set out by Stein and Ales Bello, as a way of understanding the human being... | ['Attitude of Health Personnel', 'Humans', 'Neoplasms', 'Religion', 'Spirituality'] | 21,340,290 | [['F01.100.050', 'N05.300.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['K01.844'], ['F02.880.705', 'K01.844.664.500']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Combined effect of DHA and á-tocopherol supplementation during bull semen cryopreservation on sperm characteristics and fatty acid composition. | The aim of this study was to investigate the effect of adding n-3 fatty acids (FA) and á-tocopherol (VE) to semen extender on freezing ability and FA composition of bull sperm. Semen was collected from 10 Iranian Holstein bulls and was pooled. In the first experiment, semen was divided into 12 groups including 4 levels... | ['Animals', 'Cattle', 'Cryopreservation', 'Docosahexaenoic Acids', 'Fatty Acids', 'Male', 'Semen Preservation', 'Spermatozoa', 'alpha-Tocopherol'] | 21,951,061 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['D10.212.302.380.410.210', 'D10.251.355.337.250', 'D10.627.430.450.375'], ['D10.251'], ['E02.792.833.890', 'E05.760.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective modifiers of glutathione biosynthesis and 'repriming' of vascular smooth muscle photorelaxation. | Photorelaxation of vascular smooth muscle (VSM) is caused by the release of nitric oxide (NO) from a finite molecular store that can be depleted by irradiating pre-contracted arteries with visible light. The ability of an 'exhausted' vessel to respond to a further period of illumination is lost temporarily but then rec... | ['Animals', 'Antimetabolites', 'Antioxidants', 'Buthionine Sulfoximine', 'Glutathione', 'In Vitro Techniques', 'Male', 'Muscle Relaxation', 'Muscle, Smooth, Vascular', 'Nitric Oxide', 'Nitroso Compounds', 'Photochemistry', 'Rats', 'Rats, Wistar', 'S-Nitrosoglutathione', 'Tail', 'Thiazoles'] | 10,928,960 | [['B01.050'], ['D27.505.519.186', 'D27.888.569.042'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.886.030.676.620.125', 'D12.125.166.676.620.125'], ['D12.644.456.448'], ['E05.481'], ['G11.427.494.554'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D01.339.387', 'D01.625.550.500'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A screening UHPLC-MS/MS method for the analysis of amyloid peptides in cerebrospinal fluid of preclinical species. | BACKGROUND: Amyloid peptides are established biomarkers for Alzheimer's disease but their analysis presents major challenges.RESULTS: In this article, we describe the use of ultra high-performance LC and API4000 triple quadrupole instrumentation for the quantification of amyloid peptides (Aâ(1-38) and Aâ(1-42)) in cere... | ['Alzheimer Disease', 'Amyloid beta-Peptides', 'Animals', 'Biomarkers', 'Cattle', 'Chromatography, High Pressure Liquid', 'Dogs', 'Drug Evaluation, Preclinical', 'Models, Animal', 'Peptide Fragments', 'Spectrometry, Mass, Electrospray Ionization', 'Tandem Mass Spectrometry'] | 21,175,366 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['D23.101'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.290.750', 'E05.337.550'], ['E05.598'], ['D12.6... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal smooth muscle cells. | AIM: To study the effects of homocysteine and copper on type 5 phosphodiesterase (PDE5) expression in cavernosal vascular smooth muscle cells (CVSMCs) and to investigate superoxide (O(2)(.-)) derived from nicotinamide adenine dinucleotide phosphate oxidase as homocysteine and copper generate O(2)(.-), and O(2)(.-) upre... | ['Animals', 'Blotting, Western', 'Chelating Agents', 'Copper', 'Cyclic Nucleotide Phosphodiesterases, Type 5', 'Data Interpretation, Statistical', 'Gene Expression Regulation, Enzymologic', 'Homocysteine', 'In Vitro Techniques', 'Male', 'Myocytes, Smooth Muscle', 'NADPH Oxidases', 'Penicillamine', 'Penis', 'Phosphodies... | 18,097,500 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D08.811.277.352.640.150.500', 'D08.811.277.352.640.155.500', 'D12.644.360.008.500', 'D12.644.360.009... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Subunit structure of 27 S thyroid iodoprotein. | The dissociation of thyroid 27 S iodoprotein by sodium dodecyl sulfate (SDS) and by succinic anhydride was investigated by means of ultracentrifugation and polyacrylamide gel electrophoresis. The iodoprotein obtained from either a human or hog was dissociated into three kinds of subunits (S-19, S-17 and S-12) by SDS tr... | ['Amino Acids', 'Animals', 'Hexoses', 'Humans', 'Iodine', 'Iodoproteins', 'Protein Conformation', 'Sialic Acids', 'Swine', 'Thyroglobulin', 'Thyroid Gland'] | 1,035,538 | [['D12.125'], ['B01.050'], ['D09.947.875.359'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400'], ['D12.776.486'], ['G02.111.570.820.709'], ['D02.241.081.844.562.668', 'D02.241.511.902.562.668', 'D09.067.687.668', 'D09.811.589.668'], ['B01.050.150.900.649.313.500.880'], ['D12.776.377.856', 'D12.776.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early smooth horizontal eye movement: a favorable prognostic sign in patients with locked-in syndrome. | Locked-in Syndrome (LIS) is a rare clinical entity consisting of quadriplegia, paralysis of lower cranial nerves, mutism, and bilateral paresis of horizontal gaze. The prognosis is usually poor. Most patients who do survive have severe residual impairment or develop chronic LIS. Review of the literature shows that reco... | ['Adult', 'Cerebral Infarction', 'Cranial Nerve Diseases', 'Diplopia', 'Eye Movements', 'Humans', 'Male', 'Medulla Oblongata', 'Pons', 'Prognosis', 'Quadriplegia'] | 2,923,543 | [['M01.060.116'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['C10.292'], ['C10.597.751.941.339', 'C11.966.339', 'C23.888.592.763.941.339'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Community acquired needlestick injuries in non-health care workers presenting to an urban emergency department. | OBJECTIVES: To review the epidemiology and demographics of community acquired needlestick injuries in non-health care workers attending an urban ED.METHODS: A retrospective analysis of patients with needlestick injuries attending the Royal Prince Alfred Hospital from 1996 to 2001.RESULTS: One hundred and twenty cases w... | ['Accidents, Occupational', 'Chi-Square Distribution', 'Emergency Service, Hospital', 'Female', 'Hospitals, Urban', 'Humans', 'Male', 'Needlestick Injuries', 'Occupational Exposure', 'Police', 'Retrospective Studies', 'Risk Factors'] | 14,992,057 | [['N06.850.135.240'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N02.278.421.660'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.986.950.500'], ['N06.850.460.350.600'], ['M01.526.373... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantitative proteomics and protein network analysis of hippocampal synapses of CaMKIIalpha mutant mice. | Quantitative analysis of synaptic proteomes from specific brain regions is important for our understanding of the molecular basis of neuroplasticity and brain disorders. In the present study we have optimized comparative synaptic proteome analysis to quantitate proteins of the synaptic membrane fraction isolated from t... | ["3' Untranslated Regions", 'Amino Acid Sequence', 'Animals', 'Calcium-Calmodulin-Dependent Protein Kinase Type 2', 'Chromatography, Liquid', 'Fluorouracil', 'Hippocampus', 'Metabolic Networks and Pathways', 'Mice', 'Mice, Mutant Strains', 'Molecular Sequence Data', 'Mutation', 'Proteome', 'Synapses', 'Synaptic Membran... | 17,625,814 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.913.696.620.682.700.125.200', 'D12.644.360.100.200', 'D12.776.476.100.200'], ['E05.196.181.400'], ['D03.383.742.698.875.404'], ['A... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Patterns of primary care utilization before and after living kidney donation. | BACKGROUND: Annual visits with a primary care provider (PCP) are recommended for living kidney donors to monitor long-term health postdonation, yet adherence to this recommendation is unknown.METHODS: We surveyed 1170 living donors from our center from 1970 to 2012 to ascertain frequency of PCP visits pre- and postdona... | ['Adult', 'Female', 'Follow-Up Studies', 'Health Behavior', 'Humans', 'Kidney Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Nephrectomy', 'Primary Health Care', 'Prognosis', 'Quality of Life', 'Surveys and Questionnaires', 'Tissue and Organ Harvesting'] | 28,457,016 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.898.656'], ['M01.060.116.630'], ['E04.950.774.435'], ['N04.590.233.727'], ['E01.789'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Blockade of GABAA receptors in the region of the anterior basolateral amygdala of rats elicits increases in heart rate and blood pressure. | Stimulation of the amygdala in rats is known to elicit increases in heart rate (HR) and blood pressure (BP) as well as locomotor activity associated with emotional arousal. The present study was conducted to localize and characterize the role of the GABA system of the amygdala in regulating these cardiovascular respons... | ['Amygdala', 'Analysis of Variance', 'Anesthesia, General', 'Animals', 'Baclofen', 'Bicuculline', 'Blood Pressure', 'Consciousness', 'Dose-Response Relationship, Drug', 'Electroencephalography', 'Heart Rate', 'Hippocampus', 'Male', 'Microinjections', 'Motor Activity', 'Rats', 'Rats, Inbred Strains', 'Receptors, GABA-A'... | 1,667,743 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E03.155.197'], ['B01.050'], ['D02.241.081.114.500.350.100'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['E01.370.600.875.249', 'G09.330.380.076'], ['F02.463.188.409', 'F02.830.233'], [... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
10-Epi-olguine from Rabdosia ternifolia. | An unsaturated lactone, 10-epi-olguine (1), has been isolated from Rabdosia ternifolia (D. Don) Hara. The structure was established by spectroscopic and X-ray crystallographic analyses. The compound displayed modest cytotoxicity in several human cancer cell lines. | ['Antineoplastic Agents, Phytogenic', 'Crystallography, X-Ray', 'Drug Screening Assays, Antitumor', 'Epoxy Compounds', 'Humans', 'Magnetic Resonance Spectroscopy', 'Plants, Medicinal', 'Pyrones', 'Tumor Cells, Cultured'] | 9,182,128 | [['D27.505.954.248.179'], ['E05.196.309.742.225'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D02.355.291.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['B01.650.560'], ['D03.383.663.718'], ['A11.251.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1. | We investigated the effects of adrenomedullin on nitric oxide synthesis by measuring the production of nitrite, a stable metabolite of nitric oxide, in cultured rat vascular smooth muscle cells. Incubation of cultures with interleukin-1beta (10 ng/mL) for 24 hours caused a significant increase in nitrite generation. Th... | ['Adrenomedullin', 'Animals', 'Arginine', 'Cells, Cultured', 'Cyclic AMP', 'Enzyme Inhibitors', 'Interleukin-1', 'Muscle, Smooth, Vascular', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitrites', 'Peptides', 'Rats', 'Rats, Sprague-Dawley', 'Vasodilator Agents', 'omega-N-Methylarginine'] | 8,641,730 | [['D06.472.699.077', 'D12.644.548.017'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D27.505.519.389'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acid-regulated gene expression of Helicobacter pylori: Insight into acid protection and gastric colonization. | BACKGROUND: The pathogen Helicobacter pylori encounters many stressors as it transits to and infects the gastric epithelium. Gastric acidity is the predominate stressor encountered by the bacterium during initial infection and establishment of persistent infection. H. pylori initiates a rapid response to acid to mainta... | ['Acids', 'Adaptation, Physiological', 'Bacterial Proteins', 'Culture Media', 'Gene Expression Regulation, Bacterial', 'Helicobacter pylori', 'Hydrogen-Ion Concentration', 'Multigene Family', 'Proteome', 'RNA, Bacterial', 'Stomach', 'Transcriptome', 'Urease', 'Virulence Factors'] | 29,696,729 | [['D01.029'], ['G07.025', 'G16.012.500'], ['D12.776.097'], ['D27.720.470.305', 'E07.206'], ['G05.308.300'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['G02.300'], ['G05.360.340.024.340.645'], ['D12.776.817'], ['D13.444.735.473'], ['A03.556.875.875'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920'], ['D0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Differential diagnosis of gallbladder distention by angiography (author's transl)]. | The angiography alterations of 42 cases with gallbladder distention in inflammatory or malignant disease are compared with 44 those of gallbaldder distension in distal occlusion of the common bile duct. Branches of the cystic artery were more frequent and wider in patients with gallbladder disease than those with dista... | ['Angiography', 'Bile Duct Neoplasms', 'Celiac Artery', 'Cholecystitis', 'Common Bile Duct', 'Diagnosis, Differential', 'Dilatation, Pathologic', 'Gallbladder Diseases', 'Gallbladder Neoplasms', 'Hepatic Artery', 'Humans', 'Pancreatic Neoplasms'] | 644,045 | [['E01.370.350.700.060', 'E01.370.370.050'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['A07.015.114.207'], ['C06.130.564.263'], ['A03.159.183.079.300'], ['E01.171'], ['C23.300.325'], ['C06.130.564'], ['C04.588.274.120.401', 'C06.130.320.401', 'C06.130.564.401', 'C06.301.120.401'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of Various Pretreatments to Fiber Post on the Push-out Bond Strength of Root Canal Dentin. | INTRODUCTION: The aim of this in vitro study was to compare the effect of different pretreatments (fiber post) with the laser-activated irrigation (LAI) technique (for removal of the smear layer) on root canal dentin in terms of push-out bond strength (PBS) in a fiber post.METHODS: Fifty freshly extracted mandibular si... | ['Agricultural Irrigation', 'Dental Bonding', 'Dental Pulp Cavity', 'Dental Restoration, Permanent', 'Dental Stress Analysis', 'Dentin', 'Humans', 'In Vitro Techniques', 'Post and Core Technique'] | 28,527,844 | [['J01.040.044'], ['E06.095'], ['A14.549.167.900.265'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['E06.308'], ['A14.549.167.900.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E06.780.346.250.500', 'E07.695.190.088.500']] | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Teamwork and solidarity: improving health care for all. | Emma Blakey considers one of most important lessons she learnt as a student nurse on placement, and explores how team work can influence patient care and how solidarity can change society. | ['Humans', 'Patient Care Team', "Practice Patterns, Nurses'", 'State Medicine', 'United Kingdom'] | 26,653,520 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.715'], ['N04.590.374.553', 'N05.300.581'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells. | Pre-clinical studies have demonstrated that farnesyltransferase inhibitors (FTIs) induce growth arrest or apoptosis in various human cancer cells independently of Ras mutations. However, the underlying mechanism remains unknown. Death receptor 5 (DR5) is a pro-apoptotic protein involved in mediating the extrinsic apopt... | ['Apoptosis', 'Caspase 8', 'Cell Line, Tumor', 'Farnesyltranstransferase', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'Membrane Proteins', 'Piperidines', 'Pyridines', 'Receptors, TNF-Related Apoptosis-Inducing Ligand', 'Recombinant Proteins', 'TNF-Related Apoptosis-Inducing Ligand', 'Transcri... | 17,493,934 | [['G04.146.954.035'], ['D08.811.277.656.262.500.126.550.800', 'D08.811.277.656.300.200.126.550.800', 'D12.644.360.024.285.037', 'D12.644.360.075.405.550.800', 'D12.644.360.075.421.037', 'D12.776.157.057.018.037', 'D12.776.476.024.320.025', 'D12.776.476.075.405.550.800', 'D12.776.476.075.421.037'], ['A11.251.210.190', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Political implications of the named-nurse concept. | This paper considers the role of the named nurse as a linchpin in the commissioning/providing cycle. It argues that, whatever the impact on patient care, nurses should be wary of claims that the introduction of named nursing through government policy demonstrates esteem for British nursing. | ['Health Policy', 'Humans', 'Politics', 'Primary Nursing', 'Quality of Health Care', 'State Medicine', 'United Kingdom'] | 7,479,133 | [['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.738'], ['N02.421.533.760'], ['N04.761', 'N05.715'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Association of Marijuana Use With Psychosocial and Quality of Life Outcomes Among Patients With Head and Neck Cancer. | Importance: Cannabis sativa, the most widely used illicit substance in Canada, has a unique ability to facilitate relaxation and relieve anxiety while reducing pain. However, no study to date has examined quality of life (QOL) and psychosocial issues in relation to the use of this drug among patients with newly diagnos... | ['Anxiety', 'Appetite', 'Depression', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Marijuana Smoking', 'Middle Aged', 'Pain Measurement', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Quality of Life'] | 30,073,295 | [['F01.470.132'], ['F02.830.071', 'G07.203.650.390.070', 'G10.261.390.070'], ['F01.145.126.350'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.610.875', 'F01.145.805.250.500'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.85... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Linking phylogenetics with population genetics to reconstruct the geographic origin of a species. | Reconstructing ancestral geographic origins is critical for understanding the long-term evolution of a species. Bayesian methods have been proposed to test biogeographic hypotheses while accommodating uncertainty in phylogenetic reconstruction. However, the problem that certain taxa may have a disproportionate influenc... | ['Animals', 'Base Sequence', 'Bayes Theorem', 'Demography', 'Drosophila', 'Drosophila Proteins', 'Female', 'Genetic Variation', 'Genetics, Population', 'Geography', 'Madagascar', 'Models, Genetic', 'Molecular Sequence Data', 'Nuclear Proteins', 'Period Circadian Proteins', 'Phylogeny', 'Sequence Analysis, DNA', 'Specie... | 15,288,072 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['G05.365'], ['H01.158.273.343.335'], ['H01.277.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Activation of skinned muscle fibres from the Norway lobster Nephrops norvegicus L. by manganese ions. | Effects of Mn2+ and Ca2+ on the mechanical properties of glycerinated myofibrillar bundles originating from slow S1 type muscle fibres of superficial flexor muscles of the lobster Nephrops norvegicus were investigated. Mn2+ (5-20 microM) activated the preparations in a dose-dependent manner. The sensitivity of myofibri... | ['Adenosine Triphosphate', 'Animals', 'Calcium', 'Manganese', 'Muscle Contraction', 'Muscle Fibers, Slow-Twitch', 'Nephropidae'] | 9,682,140 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['G11.427.494'], ['A10.690.552.500.500.700', 'A11.620.249.700'], ['B01.050.500.131.365.190.550']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Resistance to extreme strategies, rather than prosocial preferences, can explain human cooperation in public goods games. | The results of numerous economic games suggest that humans behave more cooperatively than would be expected if they were maximizing selfish interests. It has been argued that this is because individuals gain satisfaction from the success of others, and that such prosocial preferences require a novel evolutionary explan... | ['Adolescent', 'Altruism', 'Biological Evolution', 'Competitive Behavior', 'Cooperative Behavior', 'Female', 'Game Theory', 'Games, Experimental', 'Humans', 'Male', 'Models, Economic', 'Models, Psychological', 'Social Behavior', 'Young Adult'] | 20,479,253 | [['M01.060.057'], ['F01.145.813.090'], ['G05.045', 'G16.075'], ['F01.145.813.105'], ['F01.145.813.115'], ['G17.388'], ['E05.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.600', 'E05.599.835.890', 'N05.715.360.750.530.500', 'N06.850.520.830.500.600'], ['E05.599.695'], ['F01.145.813'], ['M01.06... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transient increase of the intracellular Ca2+ concentration during chemotactic signal transduction in Dictyostelium discoideum cells. | In general, calcium has been believed to control a variety of cellular processes as a signal transducer, with a high degree of spatial and temporal precision. For the determination of intracellular free-calcium concentrations [( Ca2+]i), the highly selective Ca2+ indicators, quin2/AM and fura2/AM, have been widely used... | ['Caffeine', 'Calcium', 'Cyclic AMP', 'Dictyostelium', 'Signal Transduction'] | 2,854,083 | [['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.046.550.200.300'], ['G02.111.820', 'G04.835']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of a polyol liquid collection medium to obtain ultrasmall magnetic nanoparticles by laser pyrolysis. | The present work addresses the main bottleneck in the synthesis of magnetic nanoparticles by laser pyrolysis. Since the introduction of laser pyrolysis for the production of nanoparticles nearly three decades ago, this method has been repeatedly presented as a highly promising alternative, on account of two main charac... | ['Cellulose', 'Lasers', 'Magnetite Nanoparticles', 'Nanotechnology', 'Particle Size', 'Photoelectron Spectroscopy', 'Polyethylene Glycols', 'Polymers', 'Temperature'] | 23,037,862 | [['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['E07.632.490', 'E07.710.520'], ['J01.637.512.600.500.144.500'], ['H01.603', 'J01.897.520.600'], ['G02.712'], ['E05.196.867.618'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D05.750', 'D25.720... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of lossy compression on lesion detection: predictions of the nonprewhitening matched filter. | The nonprewhitening matched filter (NPWMF) was used to study the effect of wavelet-based lossy image compression on lesion detectability. Two classes of images, representing lesion-present and lesion-absent cases, were generated by simulation techniques. The performance index, da, of the NPWMF was calculated from the r... | ['Biophysical Phenomena', 'Biophysics', 'Evaluation Studies as Topic', 'Humans', 'Image Processing, Computer-Assisted', 'Radiographic Image Enhancement'] | 9,775,366 | [['G01.154'], ['H01.158.344', 'H01.671.100'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Respiratory disorders in Sj?gren's syndrome: its comparison with scleroderma and normal state]. | The respiratory system was evaluated in 40 patients with primary Sjogren's syndrome (pSS) and its involvement was compared with that of 26 patients with secondary Sjogren's syndrome (sSS), 40 with rheumatoid arthritis (RA), 30 with scleroderma and 100 matched healthy controls using questionnaire, physical examination a... | ['Humans', 'Lung Diseases', 'Reference Values', 'Respiration', 'Respiration Disorders', 'Scleroderma, Systemic', "Sjogren's Syndrome"] | 3,394,096 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['E05.978.810'], ['G09.772.705'], ['C08.618'], ['C17.300.799', 'C17.800.784'], ['C05.550.114.154.774', 'C05.799.114.774', 'C07.465.815.929.669', 'C11.496.260.719', 'C17.300.775.099.774', 'C20.111.199.774']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Downregulation MIWI-piRNA regulates the migration of Schwann cells in peripheral nerve injury. | Although MIWI (PIWI in humans) regulates spermatogenesis and translation machinery, its role in peripheral nerve injury is poorly understood. In this study, we characterized the expression profiles of MIWI after sciatic nerve injury. The results revealed that MIWI was downregulated after sciatic nerve injury. MIWI was ... | ['Animals', 'Argonaute Proteins', 'Cell Movement', 'Cells, Cultured', 'Down-Regulation', 'Mice', 'Mice, Inbred C57BL', 'Peripheral Nerve Injuries', 'RNA, Small Interfering', 'Schwann Cells'] | 31,540,693 | [['B01.050'], ['D08.811.277.352.355.350.810.500', 'D08.811.277.352.700.350.810.500', 'D12.776.157.725.500.906.500', 'D12.776.664.962.500.906.500'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First experiences with Swan-Ganz measurements in patients with severe hypertension during pregnancy from an unselected population. | In 10 patients with severe hypertension during pregnancy (6 patients with preexisting hypertension and 4 with severe preeclampsia) Swan-Ganz measurements were done in order to detect and correct a reduced circulating volume and lower the blood pressure. It appeared that 6 patients had a reduced circulating volume (grou... | ['Adolescent', 'Adult', 'Antihypertensive Agents', 'Blood Pressure', 'Blood Volume', 'Blood Volume Determination', 'Cardiac Catheterization', 'Cesarean Section', 'Female', 'Humans', 'Hypertension', 'Pre-Eclampsia', 'Pregnancy'] | 3,956,832 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.188.130', 'G09.330.380.092'], ['E01.370.370.150'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E04.520.252.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C13.703.395.249... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination. | The major challenge for progressive multiple sclerosis therapy is the promotion of remyelination from inflammation-induced demyelination. A switch from an M1- to an M2-dominant polarization of microglia is critical in these repair processes. In this study, we identified the homeobox gene msh-like homeobox-3 (Msx3) as a... | ['Animals', 'Apoptosis', 'Cell Polarity', 'Cells, Cultured', 'Demyelinating Diseases', 'Encephalomyelitis, Autoimmune, Experimental', 'Female', 'Gene Expression Regulation', 'Homeodomain Proteins', 'Humans', 'Janus Kinase 3', 'Mice', 'Microglia', 'Myelin Sheath', 'Nerve Degeneration', 'Neurites', 'PPAR gamma', 'STAT6 T... | 25,904,788 | [['B01.050'], ['G04.146.954.035'], ['G04.250'], ['A11.251'], ['C10.314'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['G05.308'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.725.124.300', 'D12.776.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple floating metatarsals: a unique injury. | Concomitant dislocation of the tarsometatarsal and metatarsophalangeal joints of foot is an extremely rare injury. Such injuries presenting in a single or adjacent dual rays have been described in few cases previously. We describe such an injury in adjacent three metatarsals of a polytrauma patient. These injuries are ... | ['Adult', 'Female', 'Humans', 'Joint Dislocations', 'Metatarsal Bones', 'Metatarsophalangeal Joint'] | 23,540,901 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['A02.835.232.043.300.492'], ['A02.835.583.378.531']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bioresorbable nanofiber-based systems for wound healing and drug delivery: optimization of fabrication parameters. | Wound healing is a complex process that often requires treatment with antibiotics. This article reports the initial development of a biodegradable polymeric nanofiber-based antibiotic delivery system. The functions of such a system would be (a) to serve as a biodegradable gauze, and (b) to serve as an antibiotic delive... | ['Anti-Bacterial Agents', 'Cefazolin', 'Drug Carriers', 'Drug Delivery Systems', 'Lactic Acid', 'Nanostructures', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Polymers', 'Wound Healing'] | 15,264,311 | [['D27.505.954.122.085'], ['D02.065.589.099.249.160', 'D02.886.665.074.160', 'D03.633.100.300.249.160'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['D02.241.511.459.450'], ['J01.637.512'], ['D05.750.728.780', 'D25.720.728.780', 'J01.637.051.720.728.780'], ['D02.241.511.459.450.500', 'D05.750.728.780.500', 'D... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Modulation of synaptic plasticity by stress hormone associates with plastic alteration of synaptic NMDA receptor in the adult hippocampus. | Stress exerts a profound impact on learning and memory, in part, through the actions of adrenal corticosterone (CORT) on synaptic plasticity, a cellular model of learning and memory. Increasing findings suggest that CORT exerts its impact on synaptic plasticity by altering the functional properties of glutamate recepto... | ['Animals', 'Anti-Inflammatory Agents', 'Biotinylation', 'Cell Membrane', 'Corticosterone', 'Electric Stimulation', 'Excitatory Postsynaptic Potentials', 'Hippocampus', 'Long-Term Potentiation', 'Male', 'Neuronal Plasticity', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate', 'Synapses'] | 22,069,501 | [['B01.050'], ['D27.505.954.158'], ['E05.601.085', 'G02.111.109', 'G03.162'], ['A11.284.149'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['E05.723.402'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['A08.186.211.180.405', 'A08.186.21... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The results of treatment of gastric cancer in the Provincial Hospital in Zielona G?ra]. | INTRODUCTION: Gastric cancer is the third leading cause of death from cancer worldwide in both sexes, following lung and breast cancer. The incidence of gastric cancer in Poland is approximately 5% in men and approximately 2.5% in women, among the complete incidence of cancers. Deaths from gastric cancer in men in Pola... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Gastrostomy', 'Humans', 'Jejunoileal Bypass', 'Laparotomy', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Palliative Care', 'Poland', 'Prognosis', 'Retrospective Studies', 'Stomach Neoplasms', 'Survival Analysis', 'Survival Rate', 'Treatment Outcome'] | 26,731,867 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.496', 'E04.579.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.650.500.062.875', 'E04.035.415', 'E04.062.875', 'E04.210.626'], ['E04.406'], ['M01.060.116.630'], ['E01.789.625'], ['E02.760.666', 'N02.421.585.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin. | Vinculin plays a role in signaling between integrins and the actin cytoskeleton. We reported earlier that F9-derived cells lacking vinculin are less spread, less adhesive, and move two times faster than wild-type F9 cells. Expression of intact vinculin in null cells restored all wild-type characteristics. In contrast, ... | ['Cell Line', 'Cell Movement', 'Humans', 'Microscopy, Confocal', 'Mutation', 'Transfection', 'Vinculin'] | 9,580,561 | [['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395'], ['G05.365.590'], ['E05.393.350.810', 'G05.728.860'], ['D12.776.220.990']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy and safety of irinotecan plus S-1 (IRIS) therapy to treat advanced/recurrent colorectal cancer. | BACKGROUND: 5-Fluorouracil (5-FU), leucovorin, and oxaliplatin (FOLFOX) therapy and 5-FU, leucovorin, and irinotecan (FOLFIRI) therapy are standard chemotherapies to treat advanced/recurrent colorectal cancer. However, these chemotherapies require continuous infusion of 5-FU for a prolonged time of 40 h or more, every ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Camptothecin', 'Colorectal Neoplasms', 'Drug Combinations', 'Female', 'Humans', 'Irinotecan', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Oxonic Acid', 'Tegafur'] | 25,075,105 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.132.151'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D26.310'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Electrophysiological characterization of voltage-gated currents in defined taste cell types of mice. | Despite extensive immunological characterization of the cells within taste buds, little is known about the functional significance of the different cell types. In this study, we use taste cells isolated from mouse vallate and foliate papillae to characterize voltage-gated currents in the three principal elongate types ... | ['ABO Blood-Group System', 'Animals', 'Cells, Cultured', 'Electric Conductivity', 'Green Fluorescent Proteins', 'Ion Channel Gating', 'Luminescent Proteins', 'Mice', 'Neural Cell Adhesion Molecules', 'Patch-Clamp Techniques', 'Taste Buds', 'Transducin'] | 12,684,446 | [['D23.050.301.290.031', 'D23.050.705.230.031'], ['B01.050'], ['A11.251'], ['G01.358.500.249.277'], ['D12.776.532.265'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['D12.776.532'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.395.550.200.250.520', 'D12.776.543.550.200.250.520', 'D23.050.301.350.250.52... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cold-season disasters on the Eurasian steppes: Climate-driven or man-made. | Socio-ecological damage from climate-related disasters has increased worldwide, including a type of cold-season disaster (dzud) that is unique to the Eurasian steppes, notably Mongolia. During 2000-2014, dzuds killed approximately 30 million livestock and impacted the Mongolian socio-economy. The contributions of both ... | ['Animals', 'Climate', 'Climate Change', 'Cold Temperature', 'Disasters', 'Ecosystem', 'Grassland', 'Humans', 'Livestock', 'Mongolia', 'Seasons', 'Snow'] | 30,283,039 | [['B01.050'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.175.374'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['N06.230.100'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275.157.531', 'N06.230.124.390'], ['B01.0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Characteristics of a low affinity passive Ca2+ influx component in rat parotid gland basolateral plasma membrane vesicles. | We have previously reported the presence of two Ca2+ influx components with relatively high (KCa = 152 +/- 79 microM) and low (KCa = 2.4 +/- 0.9 mM) affinities for Ca2+ in internal Ca2+ pool-depleted rat parotid acinar cells [Chauthaiwale et al. (1996) Pfluegers Arch. 432: 105-111]. We have also reported the presence o... | ['Animals', 'Calcium', 'Cations, Divalent', 'Cell Membrane', 'Cells, Cultured', 'Kinetics', 'Male', 'Nickel', 'Parotid Gland', 'Potassium Chloride', 'Rats', 'Rats, Wistar', 'Zinc'] | 9,538,507 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300.333'], ['A11.284.149'], ['A11.251'], ['G01.374.661', 'G02.111.490'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.549.760.464'], ['D01.210.450.150.750', 'D01.745.625'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of total iron-reactive phenolics, anthocyanins and tannins in wine grapes of skins and seeds based on near-infrared hyperspectral imaging. | Phenolics contents in wine grapes are key indicators for assessing ripeness. Near-infrared hyperspectral images during ripening have been explored to achieve an effective method for predicting phenolics contents. Principal component regression (PCR), partial least squares regression (PLSR) and support vector regression... | ['Anthocyanins', 'Iron', 'Phenol', 'Seeds', 'Tannins', 'Vitis', 'Wine'] | 28,764,071 | [['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D02.455.426.559.389.657.595'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D05.750.078.937'], ['B01.650.940.800.575.912.250.965.500'], ['G07.203.100.10... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Radiotherapy for unresectable sinonasal cancers: dosimetric comparison of intensity modulated radiation therapy with coplanar and non-coplanar volumetric modulated arc therapy. | BACKGROUND AND PURPOSE: To compare volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) plans for treatment of unresectable paranasal sinuses cancers (PNSCs) with different clinical presentations.MATERIAL AND METHODS: Four patients treated for primary target volume only (group 1), fo... | ['Humans', 'Paranasal Sinus Neoplasms', 'Radiometry', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Intensity-Modulated'] | 25,467,003 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.650.693', 'C08.460.669.693', 'C08.460.692.503', 'C08.785.600.693', 'C09.603.669.693', 'C09.603.692.503', 'C09.647.685.693'], ['E05.799'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E02.815.635.700.700', 'L01.313.500.750.100.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Laparoscopic single-anastomosis duodenal-jejunal bypass with sleeve gastrectomy (SADJB-SG): short-term result and comparison with gastric bypass. | Laparoscopic duodeno-jejunal bypass with sleeve gastrectomy (DJB-SG) has been introduced as a novel metabolic surgery from Asia recently. It provides benefits of avoiding the risk of remnant gastric cancer, minimization of malnutrition from duodenal switch. Here, we introduce the technique of single-loop anastomosis du... | ['Adult', 'Anastomosis, Surgical', 'Bariatric Surgery', 'Duodenum', 'Female', 'Gastrectomy', 'Gastric Bypass', 'Humans', 'Jejunum', 'Laparoscopy', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Treatment Outcome'] | 23,990,452 | [['M01.060.116'], ['E04.035'], ['E02.650.500.062', 'E04.062'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E04.210.419'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.500', 'A03.556.249.750'], ['E01.370.388.250.520', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. | Members of the Mps1 protein kinase family have been implicated in the regulation of the kinetochore-mediated spindle assembly checkpoint in species ranging from yeast to man. However, conflicting data have been reported on the subcellular localization of vertebrate Mps1 kinases and their possible roles in centrosome du... | ['Antibodies', 'Binding Sites', 'Cell Cycle Proteins', 'Centrosome', 'Cytoskeletal Proteins', 'Humans', 'Immunohistochemistry', 'Kinetochores', 'Microtubules', 'Nuclear Proteins', 'Protein Kinases', 'Protein-Serine-Threonine Kinases', 'Protein-Tyrosine Kinases'] | 15,235,793 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G02.111.570.120'], ['D12.776.167'], ['A11.284.430.214.190.750.585.160', 'A11.284.430.214.190.750.820.500.500'], ['D12.776.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Antigen presentation by the CD4 positive monocyte subset. | Although CD4 antigen is expressed on monocytes (MO), its functional role is uncharacterized. In this study, isolated human MO were separated into CD4+ and CD4- MO subsets and assessed for presentation of tetanus toxoid. The CD4- MO subset had decreased antigen presenting cell (APC) capacity as well as increased PGE2 pr... | ['Adult', 'Antigen-Presenting Cells', 'CD4 Antigens', 'Cell Separation', 'Dinoprostone', 'Humans', 'Interleukin-1', 'Middle Aged', 'Monocytes', 'Plasminogen Activators', 'T-Lymphocytes', 'Tetanus Toxoid', 'Tumor Necrosis Factor-alpha'] | 2,303,746 | [['M01.060.116'], ['A11.066', 'A15.382.066'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Interleukin-5 regulates genes involved in B-cell terminal maturation. | Interleukin (IL)-5 induces CD38-activated splenic B cells to differentiate into immunoglobulin M-secreting cells and undergo micro to gamma 1 class switch recombination (CSR) at the DNA level, resulting in immunoglobulin G1 (IgG1) production. Interestingly, IL-4, a well-known IgG1-inducing factor does not induce immuno... | ['ADP-ribosyl Cyclase 1', 'Animals', 'B-Lymphocytes', 'Cell Differentiation', 'Cells, Cultured', 'Cytidine Deaminase', 'Cytosine Deaminase', 'Data Interpretation, Statistical', 'Flow Cytometry', 'Gene Expression Regulation', 'Immunoglobulin Class Switching', 'Immunoglobulin G', 'Immunoglobulin M', 'Interleukin-4', 'Int... | 16,895,557 | [['D08.811.277.450.430.400.060.500', 'D12.776.543.550.045'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.152'], ['A11.251'], ['D08.811.277.151.486.250'], ['D08.811.277.151.486.625'], ['E05.245.380', 'E05.318.740.300', 'L01.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Ocular manifestation of toxoplasmosis in children]. | The paper presents contemporary opinions on toxoplasmosis infection in the children, commonest form of posterior uveitis. Different clinical forms of ocular affection, current by available diagnostic methods, possible therapeutic approaches, their indications and contraindications, are analyzed. Risk of transplacentar ... | ['Child', 'Diagnosis, Differential', 'Female', 'Humans', 'Pregnancy', 'Toxoplasmosis, Ocular'] | 10,500,331 | [['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C01.610.300.781', 'C01.610.752.250.800.640', 'C11.294.725.781']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A novel method for sentinel lymph node mapping using magnetite]. | The detection rate of sentinel lymph nodes using isosulfan blue dye is too low for clinical use. Although exposure to radioactivity is reportedly minimal, special procedures are nonetheless required when a radioactive isotope is used as a tracer. Therefore, to eliminate the need for a radioactive tracer and to obtain a... | ['Contrast Media', 'Dextrans', 'Ferrosoferric Oxide', 'Humans', 'Iron', 'Magnetics', 'Magnetite Nanoparticles', 'Oxides', 'Sensitivity and Specificity', 'Sentinel Lymph Node Biopsy'] | 14,628,710 | [['D27.505.259.500', 'D27.720.259'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D01.490.100.375', 'D01.490.200.350', 'D01.578.285'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['H01.671.493'], ['J01.637.512.600.500.144.500'], ['D01.248.497.158.685', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
The challenges of IRB review and human subjects protections in practice-based research. | Practice-based research raises unique challenges with respect to human subjects protections and institutional review board (IRB) review. In this paper, three challenges posed by practice-based research are analyzed: (1) IRB review for clinician investigators who are not affiliated with an institution that has an IRB; (... | ['Ethics', 'Ethics Committees, Research', 'Human Experimentation', 'Humans', 'Peer Review, Research', 'Research', 'United States'] | 12,021,678 | [['K01.752.566.479', 'N05.350'], ['K01.752.566.479.147.750', 'N04.452.758.788.300.750', 'N05.350.268.750', 'N05.700.685.300.750'], ['E05.445', 'H01.770.644.145.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.316.549.700', 'H01.770.644.487', 'I01.880.604.640.700', 'L01.143.865.750', 'L01.737.640', 'N03... | ['Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
The KRAB zinc finger gene ZNF74 encodes an RNA-binding protein tightly associated with the nuclear matrix. | We previously cloned ZNF74, a developmentally expressed zinc finger gene commonly deleted in DiGeorge syndrome. Here, the intron/exon organization of the human gene and the functional properties of the expressed protein are presented. This zinc finger gene from the transcription factor IIIA/Kruppel family contains thre... | ['Amino Acid Sequence', 'Cell Compartmentation', 'Consensus Sequence', 'DNA Mutational Analysis', 'Genes', 'Humans', 'Introns', 'Kruppel-Like Transcription Factors', 'Molecular Sequence Data', 'Nuclear Matrix', 'RNA-Binding Proteins', 'Sequence Deletion', 'Sodium Chloride', 'Structure-Activity Relationship', 'Zinc', 'Z... | 8,663,113 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G04.128'], ['G02.111.570.580.175'], ['E05.393.760.700.300'], ['G05.360.340.024.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['D12.776.260.522', 'D12.776.930.375'], ['L01.453.245.667'], ['A11.284.430.106... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Structural changes in halophilic and non-halophilic proteases in response to chaotropic reagents. | Halophilic enzymes have been established for their stability and catalytic abilities under harsh operational conditions. These have been documented to withstand denaturation at high temperature, pH, organic solvents, and chaotropic agents. However, this stability is modulated by salt. The present study targets an impor... | ['Bacillus', 'Bacterial Proteins', 'Enzyme Stability', 'Guanidine', 'Peptide Hydrolases', 'Protein Denaturation', 'Sodium Chloride'] | 25,008,068 | [['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['D12.776.097'], ['E05.916.360', 'G02.111.700.500'], ['D02.078.370.472'], ['D08.811.277.656'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['D01.210.450.150.875', 'D01.857.650']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Orientation-dependent transcriptional activator upstream of a human U2 snRNA gene. | We examined the structure of the promoter for the human U2 snRNA gene, a strong RNA polymerase II transcription unit without an obvious TATA box. A set of 5' deletions was constructed and assayed for the ability to direct initiation of U2 snRNA after microinjection into Xenopus oocytes. Sequences between positions -295... | ['Animals', 'Base Sequence', 'Enhancer Elements, Genetic', 'Female', 'Gene Expression Regulation', 'Genes, Regulator', 'Humans', 'Molecular Weight', 'Mutation', 'Oocytes', 'Promoter Regions, Genetic', 'RNA', 'RNA, Small Nuclear', 'Transcription, Genetic', 'Xenopus laevis'] | 2,410,771 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['G05.308'], ['G05.360.340.024.340.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.494'], ['G05.365.590'], ['A05.360.490.690.680', 'A11.497.497.60... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Detection of ventilation unevenness by nitrogen washout and forced vital capacity manoeuvres: its limits and reliability. | We investigated the behaviour of several indices of ventilation unevenness in a sample of 234 normal subjects aged between 20 and 80 years, divided into 12 classes of 5 years each. The aim of the present study was to find out whether it is possible to predict a reliable value for each of these indices as a function of ... | ['Adult', 'Aged', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nitrogen', 'Regression Analysis', 'Respiratory Function Tests', 'Total Lung Capacity', 'Vital Capacity'] | 4,059,669 | [['M01.060.116'], ['M01.060.116.100'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D01.268.604', 'D01.362.625'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E01.370.386.700'], ['E01.370.386.700.485.750', 'G09.772.850'], ['E01.370.386.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Possible role of alpha-2-noradrenergic receptors in modulation of sexual behavior in female guinea pigs. | These studies examine whether alpha 1-noradrenergic receptor stimulation alone is sufficient to facilitate lordosis behavior in ovariectomized, estrogen-primed female guinea pigs and to what extent alpha 2-noradrenergic receptors are involved in this steroid-dependent behavior. Neither of the alpha 1-agonists, phenylep... | ['Adrenergic alpha-Antagonists', 'Animals', 'Clonidine', 'Dioxanes', 'Estradiol', 'Female', 'Guinea Pigs', 'Idazoxan', 'Methoxamine', 'Ovariectomy', 'Phenylephrine', 'Posture', 'Progesterone', 'Receptors, Adrenergic, alpha', 'Sexual Behavior, Animal', 'Yohimbine'] | 2,886,935 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['B01.050'], ['D03.383.129.308.436.500'], ['D03.383.188'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.992.550'], ['D03.383.129.308.428', 'D03.383.188.425', 'D03.633.100.355'], ['D02.033.100.624.536', 'D02.033.755.624... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of Salmonella enterica serovar typhi in bile and stool of patients with biliary diseases and those requiring biliary drainage for other purposes. | Acute suppurative cholangitis is a serious complication of biliary obstructions due to infection. Salmonella enterica serovar Typhi is an important biliary pathogen. Bile samples from 445 patients with biliary diseases as well as those requiring biliary drainage for other miscellaneous gastrointestinal diseases were in... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bile', 'Biliary Tract Diseases', 'Feces', 'Female', 'Humans', 'Liver Diseases', 'Male', 'Middle Aged', 'Salmonella typhi'] | 16,377,868 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A12.200.087'], ['C06.130'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['M01.060.116.630'], ['B03.440.450.425.800.200.800', 'B03.660.250.150.710.160.750']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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