Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Do antidepressants affect the self? A phenomenological approach. | In this paper, I explore the questions of how and to what extent new antidepressants (selective serotonin-reuptake inhibitors, or SSRIs) could possibly affect the self. I do this by way of a phenomenological approach, using the works of Martin Heidegger and Thomas Fuchs to analyze the roles of attunement and embodiment... | ['Antidepressive Agents, Second-Generation', 'Ego', 'Ethics, Medical', 'Humans', 'Mental Disorders', 'Philosophy, Medical', 'Serotonin Uptake Inhibitors'] | 17,476,581 | [['D27.505.954.427.700.122.050'], ['F01.752.747.189', 'F02.739.794.206'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['K01.752.667'], ['D27.505.519.562.437.850', 'D27.505.519.625.600.850', 'D27.505.519.625.850.900', 'D27.505.696.577.600.850', 'D27.5... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Treatment of chronic pain with nerve blocks and stimulation. | Nerve blocks and impulse augmentation represent two relatively noninvasive somatic procedures of use in the treatment of some chronic pain patients. In this paper the author outlines the clinical evidence for these procedures and the nature of the procedures. The author argues for their usefulness in modulating pain an... | ['Afferent Pathways', 'Central Nervous System', 'Combined Modality Therapy', 'Electric Stimulation Therapy', 'Humans', 'Nerve Block', 'Nociceptors', 'Pain', 'Pain Management', 'Prognosis', 'Skin', 'Transcutaneous Electric Nerve Stimulation'] | 6,607,191 | [['A08.612.220'], ['A08.186'], ['E02.186'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E03.155.086.711', 'E04.525.210.550'], ['A08.675.650.915.875', 'A08.800.950.875', 'A11.671.650.915.875'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.745', 'N... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Impact of bronchial epithelium on dendritic cell migration and function: modulation by the bacterial motif KpOmpA. | Mucosal immune response depends on the surveillance network established by dendritic cells (DC), APC localized within the epithelium. Bronchial epithelial cells (BEC) play a pivotal role both in the host defense and in the pathogenesis of inflammatory airway disorders. We previously showed that the outer membrane prote... | ['Administration, Intranasal', 'Animals', 'Bacterial Outer Membrane Proteins', 'Bronchi', 'CD11c Antigen', 'Cell Movement', 'Chemokines', 'Coculture Techniques', 'Cytokines', 'Dendritic Cells', 'Epithelium', 'Histocompatibility Antigens Class II', 'Humans', 'Intercellular Adhesion Molecule-1', 'Mice', 'Mice, Inbred BAL... | 17,056,515 | [['E02.319.267.120.655.500'], ['B01.050'], ['D12.776.097.120', 'D12.776.543.100'], ['A04.411.125'], ['D12.776.395.550.200.074.875', 'D12.776.395.550.200.275.500', 'D12.776.543.550.200.093.875', 'D12.776.543.550.200.275.500', 'D12.776.543.750.705.408.100.200', 'D12.776.543.750.705.408.600.100.500', 'D12.776.543.750.705.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intrapartum vibratory acoustic stimulation of the human fetus during episodes of decreased heart rate variability. | The effects of intrapartum vibratory acoustic stimulation during periods of decreased fetal heart rate variability were studied in 25 healthy term fetuses. Fetal monitoring and real-time ultrasound scanning were used simultaneously to detect fetal response. Vibratory acoustic stimulation was provided by an artificial l... | ['Acoustic Stimulation', 'Female', 'Fetal Monitoring', 'Fetal Movement', 'Heart Rate, Fetal', 'Humans', 'Labor, Obstetric', 'Pregnancy', 'Vibration'] | 3,425,643 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['E01.370.378.230', 'E01.370.520.230'], ['G07.345.500.325.235.374', 'G08.686.784.170.157.374'], ['G09.330.380.500.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326'], ['G08.686.784.769'], ['G01.374.930']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anaerobic batch conversion of pine wood torrefaction condensate. | Organic compound rich torrefaction condensate, owing to their high water content and acidic nature, have yet to be exploited for practical application. In this study, microbial conversion of torrefaction condensate from pine wood through anaerobic batch digestion (AD) to produce methane was evaluated. Torrefaction cond... | ['Anaerobiosis', 'Bioreactors', 'Hot Temperature', 'Methane', 'Pinus', 'Wood'] | 27,898,321 | [['G02.111.062', 'G03.078'], ['E07.115', 'J01.897.120.115'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D02.455.326.146.571'], ['B01.650.940.800.575.912.625.875.777'], ['A18.450.500.500', 'J01.637.241.900']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Malaria co-infection in children influences antibody response to schistosome antigens and inflammatory markers associated with morbidity. | The epidemiological coexistence of schistosomiasis and malaria is frequently observed in developing countries. Co-infection with malaria in children could influence the development of acquired immunity associated with the resistance or the pathology of schistosomiasis. In the present study, performed during May to June... | ['Adolescent', 'Animals', 'Antibodies, Helminth', 'Antibody Specificity', 'Antigens, Helminth', 'Child', 'Cytokines', 'Female', 'Glutathione Transferase', 'Helminth Proteins', 'Humans', 'Inflammation Mediators', 'Malaria, Falciparum', 'Male', 'Schistosoma haematobium', 'Schistosomiasis haematobia'] | 15,228,260 | [['M01.060.057'], ['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['G12.100'], ['D23.050.223'], ['M01.060.406'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D08.811.913.225.500'], ['D12.776.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Patterns of recurrence after curative resection of pancreatic ductal adenocarcinoma. | AIMS: Despite curative surgery for pancreatic ductal adenocarcinoma (PDAC), most patients develop cancer recurrence and die from metastatic disease. Understanding of the patterns of failure after surgery can lead to new insights for novel therapeutic modalities. The aim of the present study is to describe the patterns ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Pancreatic Ductal', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Pancreatic Neoplasms', 'Retrospective Studies', 'Survival Analysis'] | 19,131,205 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.625', 'C19.344.421.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.55... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dissociable stages of problem solving (II): first evidence for process-contingent temporal order of activation in dorsolateral prefrontal cortex. | In a companion study, eye-movement analyses in the Tower of London task (TOL) revealed independent indicators of functionally separable cognitive processes during problem solving, with processes of building up an internal representation of the problem preceding actual planning processes. These results imply that proces... | ['Adult', 'Brain Mapping', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Neuropsychological Tests', 'Prefrontal Cortex', 'Problem Solving'] | 22,445,816 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['F04.711.513'], ['A08.186.211.200.885.287.500.270.700'], ['F02.463.425.725', 'F02.463.785.810']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Simple protocol for extracting diatoms from lung tissues of suspected drowning cases within 3h: First practical application. | Conventional acid digestion of tissues for analyzing diatoms obtained from suspected drowning cases is time-consuming, laborious and potentially dangerous. We propose a new protocol for solubilizing lung tissue using only Qiagen Proteinase K, Qiagen Buffer ATL, and 5N hydrochloric acid that can accelerate and simplify ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Centrifugation', 'Diatoms', 'Drowning', 'Endopeptidase K', 'Forensic Medicine', 'Humans', 'Hydrochloric Acid', 'Incubators', 'Lung', 'Middle Aged'] | 25,911,496 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.181'], ['B01.750.200'], ['C23.550.260.393', 'C26.304', 'N06.850.135.696'], ['D08.811.277.656.300.760.247', 'D08.811.277.656.959.350.247'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.326', 'D01.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Herpes simplex type 1 defective interfering particles do not affect the antiviral activity of acyclovir, foscarnet and adenine arabinoside. | The concentration of defective interfering particles (DI-particles) of herpes simplex type 1 virus was analysed by electron microscopy and plaque titration. Fifteen consecutive passages of undiluted virus in green monkey kidney cells were followed. No relationship was found between the concentration of DI-particles and... | ['Acyclovir', 'Animals', 'Defective Viruses', 'Foscarnet', 'Organophosphorus Compounds', 'Phosphonoacetic Acid', 'Serial Passage', 'Simplexvirus', 'Vidarabine'] | 2,899,962 | [['D03.633.100.759.758.399.454.250'], ['B01.050'], ['B04.265'], ['D02.241.081.018.677.250', 'D02.705.429.875.500'], ['D02.705'], ['D02.241.081.018.677', 'D02.705.429.875'], ['E01.370.225.875.837', 'E05.200.875.837'], ['B04.280.382.100.750'], ['D03.633.100.759.590.138.900', 'D13.570.065.950', 'D13.570.583.138.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of differentially expressed genes involved in early bolting of Angelica sinensis (Apiaceae). | Angelica sinensis is a highly valued medicinal herb, known as female ginseng that is widely cultivated in China. Although A. sinensis is in great demand due to its multiple medicinal and food applications, its early bolting rate (almost 40%) seriously affects crop quality. To better understand its flowering mechan... | ['Amplified Fragment Length Polymorphism Analysis', 'Angelica sinensis', 'DNA, Complementary', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Molecular Sequence Annotation'] | 22,535,385 | [['E05.393.290.382', 'E05.393.620.500.324'], ['B01.650.940.800.575.912.250.075.088.538'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['E05.393.332'], ['G05.308.375'], ['E05.393.760.479', 'L01.453.245.667.580']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Class and subclass distribution of Hantavirus-specific serum antibodies at different times after the onset of nephropathia epidemica. | Sera from Dutch and Belgium individuals who suffered from nephropathia epidemica (NE), a mild form of haemorrhagic fever with renal syndrome (HFRS), were tested for the distribution of classes and subclasses of Hantavirus (HV)-specific antibodies at different times after the onset of the disease, with class- and subcla... | ['Adolescent', 'Adult', 'Antibodies, Viral', 'Belgium', 'Convalescence', 'Creatinine', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Hantavirus', 'Hemorrhagic Fever with Renal Syndrome', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Kidney Diseases', 'Male', 'Middle Aged', 'Netherlands', 'Pro... | 7,916,034 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['Z01.542.115'], ['C23.550.291.562'], ['D03.383.129.308.207'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B04.820.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Do Medicare Advantage plans select enrollees in higher margin clinical categories? | The CMS-HCC risk adjustment system for Medicare Advantage (MA) plans calculates weights, which are effectively relative prices, for beneficiaries with different observable characteristics. To do so it uses the relative amounts spent per beneficiary with those characteristics in Traditional Medicare (TM). For multiple r... | ['Confidence Intervals', 'Humans', 'Managed Care Programs', 'Medicare Part C', 'Risk Adjustment', 'United States'] | 24,308,879 | [['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['N03.219.521.346.506.564.663.757', 'N03.219.521.576.343.840.877', 'N03.706.615.420.249'], ['N04.452.871.715.800', 'N04.761.789.800', 'N05.715.360.750.625.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Sequential combination chemotherapy and radiotherapy in locally advanced non-small cell carcinoma of the bronchus. | The feasibility, effectiveness and toxicity of a new four drug intensive combination chemotherapy regime has been assessed in 36 patients with inoperable non-small cell lung cancer. Three cycles of adriamycin, vindesine, ifosfamide and cisplatin were given to 36 patients followed by sequential radiotherapy to 25 patien... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Bronchial Neoplasms', 'Carcinoma, Small Cell', 'Cisplatin', 'Combined Modality Therapy', 'Doxorubicin', 'Feasibility Studies', 'Female', 'Humans', 'Ifosfamide', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Pilot Projects',... | 2,556,735 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['C04.557.470.200.380'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.186'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Spa2-related protein, Sph1p, is important for polarized growth in yeast. | The Saccharomyces cerevisiae protein Sph1p is both structurally and functionally related to the polarity protein, Spa2p. Sph1p and Spa2p are predicted to share three 100-amino acid domains each exceeding 30% sequence identity, and the amino-terminal domain of each protein contains a direct repeat common to Homo sapiens... | ['Adaptor Proteins, Signal Transducing', 'Amino Acid Sequence', 'Carrier Proteins', 'Cell Polarity', 'Cytoskeletal Proteins', 'Fungal Proteins', 'MAP Kinase Kinase 1', 'MAP Kinase Kinase 2', 'Microfilament Proteins', 'Mitogen-Activated Protein Kinase Kinases', 'Molecular Sequence Data', 'Open Reading Frames', 'Protein ... | 9,443,897 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157'], ['G04.250'], ['D12.776.220'], ['D12.776.354'], ['D08.811.913.696.620.682.700.565.100', 'D08.811.913.696.620.682.725.200.100', 'D12.644.360.440.100', 'D12.776.476.440.100'], ['D08.811.913.696.620.682.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Leishmania histone H1 overexpression delays parasite cell-cycle progression, parasite differentiation and reduces Leishmania infectivity in vivo. | Episomal expression of Leishmania histone H1 sense mRNAs in Leishmania major promastigotes was found previously to result in overexpression of this molecule and to reduce parasite infectivity in vitro. Herein, we evaluated the in vivo infectivity of these transfectants, in BALB/c mice, and showed that it is dramaticall... | ['Animals', 'COS Cells', 'Cell Cycle', 'Cell Differentiation', 'Chlorocebus aethiops', 'Histones', 'Leishmania donovani', 'Leishmania major', 'Mice', 'Mice, Inbred BALB C', 'NIH 3T3 Cells', 'Nocodazole', 'Protozoan Proteins', 'Transcriptional Activation', 'Virulence'] | 16,796,681 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['G04.144'], ['G04.152'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.268.475.868.488.230'], ['B01.268.475.868.488.405'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy. | Duchenne muscular dystrophy (DMD) causes profound and progressive muscle weakness and loss, resulting in early death. DMD is usually caused by frameshifting deletions in the gene DMD, which leads to absence of dystrophin protein. Dystrophin binds to F-actin and components of the dystrophin-associated glycoprotein compl... | ['Animals', 'Cell Line', 'Dantrolene', 'Disease Models, Animal', 'Drug Synergism', 'Dystrophin', 'Exons', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Injections, Intramuscular', 'Mice', 'Mice, Inbred C57BL', 'Muscle Fibers, Skeletal', 'Muscular Dystrophy, Animal', 'Muscular Dystrophy, Duchenne', 'Oligonucleotid... | 23,241,744 | [['B01.050'], ['A11.251.210'], ['D03.383.129.308.432.555.287'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.968.477'], ['D12.776.210.500.250', 'D12.776.220.250', 'D12.776.543.250'], ['G05.360.340.024.340.137.232'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A continuous penalty function method for inverse treatment planning. | Conventional inverse treatment planning attempts to calculate dose distributions that may not be feasible given the specified dose levels to various anatomical structures. A technique for inverse treatment planning has been developed that uses only target dose levels which are easily selectable to be feasible. A nonlin... | ['Biophysical Phenomena', 'Biophysics', 'Humans', 'Models, Theoretical', 'Neoplasms', 'Phantoms, Imaging', 'Photons', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, High-Energy'] | 9,507,482 | [['G01.154'], ['H01.158.344', 'H01.671.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['C04'], ['E07.671'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['E02.815.722']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Community rehabilitation for persons with psychiatric disabilities: comparison of the effectiveness of segregated and integrated programs in Israel. | This study compares the effectiveness of a segregative and an integrative psychosocial recreational program for persons with psychiatric disabilities in Israel. Comparison of changes in 97 members of a segregated social club with those of 89 participants in an integrative program in their local community center shows t... | ['Adult', 'Female', 'Friends', 'Humans', 'Israel', 'Leisure Activities', 'Loneliness', 'Male', 'Mental Disorders', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Patient Satisfaction', 'Quality of Life', 'Recreation', 'Residence Characteristics', 'Self-Help Groups', 'Social Environment', 'Social Support... | 18,018,958 | [['M01.060.116'], ['M01.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['I03.450'], ['F01.470.713', 'I01.880.853.748.435'], ['F03'], ['M01.060.116.630'], ['N04.761.559', 'N05.715.360.575'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.71... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Breast lesions: evaluation with US strain imaging--clinical experience of multiple observers. | PURPOSE: To prospectively determine the accuracy of using an ultrasonographic (US) strain imaging technique known as lesion size comparison to differentiate benign from malignant breast lesions.MATERIALS AND METHODS: Institutional Review Board approval and patient informed consent were obtained for this HIPPA-compliant... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged', 'Observer Variation', 'Prospective Studies', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Ultrasonography'] | 16,436,810 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.65... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Citizenship, Vulnerability and Mental Incapacity in England, 1900-1960s. | Over the twentieth century, the Lunacy Office (renamed the Court of Protection in 1947) was responsible for appointing 'receivers' to manage the property of adults in England who were found incapable of managing their own affairs. Tens of thousands of people were in this position by the 1920s, and numbers continued to ... | ['Civil Rights', 'England', 'Female', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Intellectual Disability', 'Legal Guardians', 'Male', 'Mental Competency', 'Mental Disorders'] | 31,208,480 | [['I01.880.604.473.352', 'N03.706.437.352'], ['Z01.542.363.300'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['M01.380'], ['F01.590', 'F02.410', 'I01.880.604.583.530', 'N03.706.535.625'], ['F03']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Isolation and characterization of a tobacco mosaic virus-inducible myb oncogene homolog from tobacco. | Salicylic acid (SA) plays an important role in signaling the activation of plant defense responses against pathogen attack including induction of pathogenesis-related (PR) proteins. To gain further insight into the SA-mediated signal transduction pathway, we have isolated and characterized a tobacco mosaic virus (TMV)-... | ['Amino Acid Sequence', 'Molecular Sequence Data', 'Oncogenes', 'Plant Proteins', 'Plants, Toxic', 'Sequence Homology, Amino Acid', 'Tobacco', 'Tobacco Mosaic Virus'] | 8,962,166 | [['G02.111.570.060', 'L01.453.245.667.060'], ['L01.453.245.667'], ['G05.360.340.024.340.375.500'], ['D12.776.765'], ['B01.650.660'], ['G02.111.810.200', 'G05.810.200'], ['B01.650.940.800.575.912.250.908.500.900'], ['B04.715.464.725.800', 'B04.820.578.844.800']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Teaching dermatoscopy of pigmented skin tumours to novices: comparison of analytic vs. heuristic approach. | BACKGROUND: There are two strategies to approach the dermatoscopic diagnosis of pigmented skin tumours, namely the verbal-based analytic and the more visual-global heuristic method. It is not known if one or the other is more efficient in teaching dermatoscopy.OBJECTIVE: To compare two teaching methods in short-term tr... | ['Adult', 'Area Under Curve', 'Carcinoma, Basal Cell', 'Dermoscopy', 'Educational Measurement', 'Female', 'Health Knowledge, Attitudes, Practice', 'Heuristics', 'Histiocytoma, Benign Fibrous', 'Humans', 'Keratosis, Seborrheic', 'Male', 'Melanoma', 'Middle Aged', 'Models, Educational', 'Nevus, Pigmented', 'Prenatal Educ... | 25,370,214 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['E01.370.350.515.277.250', 'E05.595.185.250'], ['I02.399'], ['F01.100.150.500', 'N05.300.150.410'], ['F02.463.425.725.500', 'F02.463.785.810.500'], ['C04.557.450.565.590.425.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
High tau levels in cerebrospinal fluid predict rapid decline and increased dementia mortality in Alzheimer's disease. | OBJECTIVE: Cerebrospinal fluid (CSF) amyloid â42 (Aâ42), total tau (t-tau) and phosphorylated tau (p-tau) are useful as predictors of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) dementia. However, results are contradictory as to whether these biomarkers reflect the future rate of clinica... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Amyloid beta-Peptides', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neuropsychological Tests', 'Phosphorylation', 'Predictive Value of Tests', 'Retrospective Studies', 'Risk Factors', 'Severity of Il... | 24,157,938 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Activation of STAT5 confers imatinib resistance on leukemic cells through the transcription of TERT and MDR1. | We used two imatinib resistant cell lines, K562-ADM cells, which over-express P-glycoprotein (a product of the ABCB1 gene, more commonly known as MDR1), and K562-hTERT cells, which over-express the telomerase reverse transcriptase (TERT), as models to show that the acquisition of multidrug resistance in CML is associat... | ['ATP Binding Cassette Transporter, Subfamily B', 'ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Antineoplastic Agents', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Benzamides', 'Blast Crisis', 'Cell Line, Tumor', 'Cell Survival', 'Doxorubicin', 'Drug Resistance, Neoplasm', 'Gene Expression Regulation, ... | 21,356,308 | [['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Day-case anaesthesia for termination of pregnancy. Evaluation of a total intravenous anaesthetic technique. | An investigation was undertaken to assess the use of a total intravenous anaesthetic technique of fentanyl and methohexitone for outpatient vaginal termination of pregnancy. When compared with a technique of fentanyl, methohexitone, nitrous oxide and trichloroethylene the total intravenous method caused swifter recover... | ['Abortion, Induced', 'Adolescent', 'Adult', 'Ambulatory Surgical Procedures', 'Anesthesia, General', 'Anesthesia, Inhalation', 'Anesthesia, Intravenous', 'Evaluation Studies as Topic', 'Female', 'Fentanyl', 'Humans', 'Memory', 'Methohexital', 'Pregnancy', 'Trichloroethylene'] | 6,638,451 | [['E04.520.050'], ['M01.060.057'], ['M01.060.116'], ['E04.030'], ['E03.155.197'], ['E03.155.197.197'], ['E03.155.308'], ['E05.337', 'N05.715.360.335'], ['D03.383.621.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['D03.383.742.698.253.488'], ['G08.686.784.769'], ['D02.455.526.439.939']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives. | We are interested in developing novel natural product-derived P-gp inhibitors to reverse cancer drug resistance. Here, we have synthesized 55 novel derivatives of methylated epigallocatechin (EGC), gallocatechin (GC), and dihydromyricetin (DHM). Three EGC derivatives (23, 35, and 36) and three GC derivatives (50, 51, a... | ['ATP Binding Cassette Transporter, Subfamily B', 'ATP Binding Cassette Transporter, Subfamily G, Member 2', 'ATP-Binding Cassette Transporters', 'Antineoplastic Agents', 'Catechin', 'Cell Proliferation', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Flavonols', 'Humans', 'Methylation', 'Models, Molecular'... | 25,985,195 | [['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['D12.776.157.530.100.228.500', 'D12.776.395.550.020.457.500', 'D12.776.543.550.192.457.500', 'D12.776.543.585.100.228.500'], ['D12... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple self-controlled case series for large-scale longitudinal observational databases. | Characterization of relationships between time-varying drug exposures and adverse events (AEs) related to health outcomes represents the primary objective in postmarketing drug safety surveillance. Such surveillance increasingly utilizes large-scale longitudinal observational databases (LODs), containing time-stamped p... | ['Case-Control Studies', 'Data Interpretation, Statistical', 'Databases, Factual', 'Drug-Related Side Effects and Adverse Reactions', 'Humans', 'Incidence', 'Longitudinal Studies', 'Observational Studies as Topic', 'Population Surveillance', 'Risk Assessment'] | 24,117,144 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C25.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Factors associated with age at operation for children with congenital heart disease. | OBJECTIVE: Previous studies have shown that children with congenital heart disease (CHD) who live in nonurban areas or who do not have private insurance are at risk for delayed referral to a pediatric cardiologist. However, the effect of these factors on the age at which cardiac surgery is performed has not been evalua... | ['Age Distribution', 'Age Factors', 'Cardiac Surgical Procedures', 'Child', 'Child, Preschool', 'Female', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Insurance, Health', 'Male'] | 10,790,465 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N05.715.350.075', 'N06.850.490.250'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['M01.060.406.448'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['N03.219.521.576.343']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The OECI model: the CRO Aviano experience. | In 2012, the "Centro di Riferimento Oncologico" (CRO) National Cancer Institute joined the accreditation program of the Organisation of European Cancer Institutes (OECI) and was one of the first institutes in Italy to receive recognition as a Comprehensive Cancer Center. At the end of the project, a strengths, weakness... | ['Accreditation', 'Benchmarking', 'Cancer Care Facilities', 'Europe', 'Hospice Care', 'Humans', 'Interdisciplinary Communication', 'International Cooperation', 'Italy', 'Leadership', 'Neoplasms', 'Organizational Culture', 'Patient Care Team', 'Patient Participation', 'Quality Assurance, Health Care'] | 27,096,265 | [['N03.706.110.070', 'N05.700.200.100'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['N02.278.421.556.070'], ['Z01.542'], ['E02.760.905.400', 'N02.421.585.905.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'], ['I01.6... | ['Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Effects of oestradiol benzoate injections, exposure to the boar and age on the attainment of puberty in the gilt. | Thirty large white cross Landrace prepubertal gilts from five litters were allocated at random within litters to one of six treatment. All the gilts were given three daily intramuscular injections of 6 micrograms/kg liveweight of oestradiol benzoate but the first injection was given at either 100 days, 120 days, 140 da... | ['Age Factors', 'Animals', 'Estradiol', 'Female', 'Fertility', 'Male', 'Ovulation', 'Progesterone', 'Sexual Maturation', 'Swine'] | 3,369,056 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.210'], ['G08.686.784.690'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['G07.345.750.750', 'G08.686.841.750'], ['B01.050.150.900.649.313.500.880']] | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
All-cause and diabetes-related healthcare costs among US adults with type 2 diabetes initiating exenatide once weekly or insulin glargine. | AIMS: To compare healthcare utilization and costs between patients with type 2 diabetes (T2D) treated with exenatide (Bydureon) once weekly (EQW) and patients treated with insulin glargine (IG).MATERIALS AND METHODS: Using the MarketScan Commercial and Medicare Supplemental databases, we conducted a retrospective cohor... | ['Adolescent', 'Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Drug Administration Schedule', 'Exenatide', 'Female', 'Health Care Costs', 'Humans', 'Hypoglycemic Agents', 'Insulin Glargine', 'Male', 'Middle Aged', 'Retrospective Studies', 'Treatment Outcome', 'Young Adult'] | 29,083,520 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.319.283'], ['D12.644.187', 'D20.888.300', 'D23.946.833.300'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.300.100', 'D12.644.548.586.2... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changing profile of couples seeking genetic counseling for consanguinity in Australia. | Consanguineous marriage is rare in most Western countries and, for example, in the USA it may be subject to regulation by both civil legislation and religious prescription. This is not the case in many regions of Asia and Africa where marriage within the family is strongly favored. Since the 1970s there has been widesp... | ['Australia', 'Consanguinity', 'Family Planning Services', 'Female', 'Genetic Counseling', 'Genetic Diseases, Inborn', 'Humans', 'Male', 'Religion'] | 15,558,724 | [['Z01.639.100', 'Z01.678.100.373'], ['G05.090.403.180', 'G05.180'], ['N02.421.143.401', 'N02.421.800.249'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['C16.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.844']] | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
CMV retinitis recurs after stopping treatment in virological and immunological failures of potent antiretroviral therapy. | OBJECTIVES: To determine predictors of clinical relapse of cytomegalovirus (CMV) end-organ disease in a cohort of 17 HIV-infected patients with healed and treated CMV retinitis (CMVR) who responded to HAART with an increase in CD4 cell counts to above 70 cells/mm3 and discontinued CMV maintenance therapy (MT).DESIGN: S... | ['AIDS-Related Opportunistic Infections', 'Adult', 'Anti-HIV Agents', 'CD4 Lymphocyte Count', 'Cohort Studies', 'Cytomegalovirus', 'Cytomegalovirus Retinitis', 'Female', 'HIV', 'Humans', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Prospective Studies', 'RNA, Viral', 'Recurrence', 'Risk Factors', 'T-Lymphocytes', '... | 10,708,288 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', ... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Knock-Out Serum Replacement and Melatonin Effects on Germ Cell Differentiation in Murine Testicular Explant Cultures. | Finding robust culture conditions for in vitro maturation (IVM) of male germ cells is still a challenge. Recently, a testis organ culture method, using Knockout Serum Replacement (KSR), was suggested as a promising approach. However, the efficiency of that model is still not optimal. Hence, we have tried to establish t... | ['Animals', 'Cell Differentiation', 'Culture Media', 'Germ Cells', 'Male', 'Melatonin', 'Mice', 'Organ Culture Techniques', 'Serum', 'Testis'] | 28,488,216 | [['B01.050'], ['G04.152'], ['D27.720.470.305', 'E07.206'], ['A05.360.490', 'A11.497'], ['D03.633.100.473.914.481', 'D06.472.506'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.481.500.484'], ['A12.207.152.846', 'A15.145.846'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.312.782']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Social and attention-to-detail subclusters of autistic traits differentially predict looking at eyes and face identity recognition ability. | This study distinguished between different subclusters of autistic traits in the general population and examined the relationships between these subclusters, looking at the eyes of faces, and the ability to recognize facial identity. Using the Autism Spectrum Quotient (AQ) measure in a university-recruited sample, we s... | ['Adolescent', 'Adult', 'Attention', 'Communication', 'Eye Movements', 'Facial Recognition', 'Female', 'Humans', 'Interpersonal Relations', 'Learning', 'Male', 'Memory', 'Photic Stimulation', 'Regression Analysis', 'Young Adult'] | 26,988,108 | [['M01.060.057'], ['M01.060.116'], ['F02.830.104.214'], ['F01.145.209', 'L01.143'], ['G11.427.410.140', 'G14.350'], ['F02.463.593.524.250.500', 'F02.463.593.524.500.500', 'F02.463.593.932.622.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes. | Glycated hemoglobin (HbA1c) is an important measure of glycemia in diabetes. HbA1c is influenced by environmental and genetic factors both in people with and in people without diabetes. We performed a genome-wide association study (GWAS) for HbA1c in a Finnish type 1 diabetes (T1D) cohort, FinnDiane. Top results were e... | ['Blood Glucose', 'Diabetes Complications', 'Diabetes Mellitus, Type 1', 'Female', 'Genome-Wide Association Study', 'Glycated Hemoglobin A', 'Humans', 'Male'] | 30,674,623 | [['D09.947.875.359.448.500'], ['C19.246.099'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prognostic factors for success in treating kidney stones by extracorporeal shock wave lithotripsy. | BACKGROUND: Extracorporeal shock wave lithotripsy (ESWL) is widely used worldwide to treat kidney stone because it is without invasive and can be done on an outpatient basis. However, not all patients are treated successfully. The success of kidney stone treatment by ESWL depends on several factors.OBJECTIVE: To invest... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Child', 'Female', 'Follow-Up Studies', 'Hospitals, University', 'Humans', 'Kidney Calculi', 'Lithotripsy', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Prognosis', 'Prospective Studies', 'Sex Distribution', 'Sex Factors', 'Treatment Outcome'] | 21,560,841 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The treatment of hirsutism with cyproterone acetate (an anti-androgen). | The rationale of anti-androgen treatment for hirsutism is explained. The results are presented of treatment with cyproterone acetate of idiopathic hirsutism or hirsutism associated with polycystic ovarian disease. Ten out of 14 patients showed a good response after six months treatment. The response was dramatic in two... | ['Adolescent', 'Adult', 'Cyproterone', 'Female', 'Hirsutism', 'Humans', 'Middle Aged', 'Polycystic Ovary Syndrome'] | 843,478 | [['M01.060.057'], ['M01.060.116'], ['D04.210.500.745.432.219', 'D04.210.500.883.419'], ['C17.800.329.750', 'C23.888.971.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.182.612.765', 'C13.351.500.056.630.580.765', 'C19.391.630.580.765']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Parathyroid hormone, 3'5' AMP, Ca++, and renal gluconeogenesis. | Isolated segments of renal tubules prepared from rat kidney cortex were capable of sustained rates of gluconeogenesis when lactate served as substrate. An increase in external Ca(++), or the addition of parathyroid hormone at a fixed Ca(++) concentration led to enhanced rate of gluconeogenesis. However, parathyroid did... | ['Adenine Nucleotides', 'Adenosine Triphosphate', 'Animals', 'Calcium', 'Chelating Agents', 'Citrates', 'Cyclic AMP', 'Gluconeogenesis', 'Glucose', 'In Vitro Techniques', 'Ketoglutaric Acids', 'Kidney Tubules', 'Malates', 'Male', 'Parathyroid Hormone', 'Pyruvates', 'Rats', 'Stimulation, Chemical'] | 4,313,196 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D02.241.081.901.434'], ['D03.633.100.759.646.138.395', 'D13... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A microcosm investigation of fe (iron) removal using macrophytes of ramsar lake: A phytoremediation approach. | The present study deals with the microcosm study of Fe (Iron) phytoremediation using Eichhornia crassipes, Lemna minor, Pistia stratiotes and Salvinia cucullata species collected from the Loktak Lake, a Ramsar Site which exists in north-eastern India (an Indo-Burma hotspot region). Efficiency of these four macrophytes ... | ['Biodegradation, Environmental', 'Dose-Response Relationship, Drug', 'Environmental Restoration and Remediation', 'India', 'Iron', 'Lakes', 'Plants', 'Water Pollutants, Chemical'] | 27,258,126 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['G07.690.773.875', 'G07.690.936.500'], ['N06.230.080.600', 'N06.850.460.375'], ['Z01.252.245.393'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['B01.650'], ['D27.888.284.903.655']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Male Accessory Gland Infections (MAGI): patient questionnaire and additional ultrasonography criteria]. | Male Accessory Gland Infections (MAGI) refers to a syndrome that has generated considerable debate recently in relation to its possible role in causing certain acquired conditions of male fertility. A further characterization of the syndrome based on symptoms and ultrasonographic findings has therefore become necessary... | ['Adult', 'Anti-Bacterial Agents', 'Case-Control Studies', 'Genital Diseases, Male', 'Humans', 'Infertility, Male', 'Male', 'Prospective Studies', 'Quality of Life', 'Seminal Vesicles', 'Sensitivity and Specificity', 'Surveys and Questionnaires', 'Ultrasonography'] | 18,971,910 | [['M01.060.116'], ['D27.505.954.122.085'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C12.294'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['I01.800', 'K01.752.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Intrauterine exposure to diabetes is a determinant of hemoglobin A(1)c and systolic blood pressure in pima Indian children. | CONTEXT/OBJECTIVE: Given the increasing rates of both childhood obesity and type 2 diabetes (T2DM), we investigated whether maternal diabetes status during pregnancy is a determinant of risk factors associated with T2DM or cardiovascular disease in offspring during childhood.DESIGN/PARTICIPANTS: Forty-two Pima Indians,... | ['Arizona', 'Child', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Indians, North American', 'Pregnancy', 'Pregnancy in Diabetics', 'Prenatal Exposure Delayed Effects', 'Retrospective Studies', 'Systole'] | 15,797,952 | [['Z01.107.567.875.760.100'], ['M01.060.406'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['G08.686.784.769'], ['C13.703.726'], ['C13.703.824.500'], ['E05.318.372.500.500.500', 'E05.318.372.5... | ['Geographicals [Z]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Implantation of the paclitaxel-eluting stent Apollo in patients with stable angina pectoris: long-term angiographic and clinical results]. | AIM: to assess the long-term angiographic and clinical results of percutaneous coronary interventions (PCI) with implantation of the drug-eluting stent (DES) Apollo in patients with stable angina pectoris.SUBJECTS AND METHODS: The study enrolled 48 patients with stable angina who had been implanted with 59 stents. A fo... | ['Angina Pectoris', 'Angioplasty, Balloon, Coronary', 'Aspirin', 'Clopidogrel', 'Coronary Angiography', 'Coronary Restenosis', 'Drug-Eluting Stents', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Paclitaxel', 'Platelet Aggregation Inhibitors', 'Ticlopidine', 'Treatment Outcome'] | 20,873,240 | [['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['D02.455.426.559.389.657.410.595.176'], ['D02.886... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Next-generation sequencing identifies 2 genomically distinct groups among pyloric gland adenomas. | The molecular alterations identified among pyloric gland adenomas (PGAs) in the published literature are based on polymerase chain reaction of targeted genes, and next-generation sequencing (NGS) has not been performed. In this study, we performed NGS and correlated the molecular alterations with the histologic grade o... | ['Adenocarcinoma', 'Adenoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'DNA Mutational Analysis', 'Female', 'Gastric Mucosa', 'Genetic Predisposition to Disease', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Mutation', 'Neoplasm Grading', 'Phenotyp... | 31,783,043 | [['C04.557.470.200.025'], ['C04.557.470.035'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E05.393.760.700.300'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C23.550.291.687.500', 'G05.380.355'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Changes in insulin-like growth factor-binding protein expression and secretion during the proliferation, differentiation, and mineralization of primary cultures of rat osteoblasts. | Insulin-like growth factor-I (IGF-I) and IGF-II are secreted by the bone-forming osteoblast and have been shown to promote mitogenesis and/or differentiation of several of the cells involved in adult bone remodeling. The biological actions of the IGFs are modulated in a cell-specific manner by IGF-binding proteins (IGF... | ['Alkaline Phosphatase', 'Animals', 'Base Sequence', 'Calcification, Physiologic', 'Cell Differentiation', 'Cell Division', 'Cells, Cultured', 'Female', 'Molecular Probes', 'Molecular Sequence Data', 'Osteoblasts', 'RNA, Messenger', 'Rats', 'Skull', 'Somatomedins'] | 8,013,356 | [['D08.811.277.352.650.035'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['D27.505.259.750', 'D27.720.47... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Isolation of methylene dianiline and aqueous-soluble biodegradation products from polycarbonate-polyurethanes. | Polycarbonate-polyurethanes (PCNUs) have provided the medical device industry with practical alternatives to oxidation-sensitive polyether-urethanes (PEUs). To date, many studies have focused on PCNUs synthesized with 4,4'-methylene diphenyl-diisocyanate (MDI). The relative hydrolytic stability of this class of polyure... | ['Aniline Compounds', 'Biocompatible Materials', 'Biodegradation, Environmental', 'Hydrolysis', 'Materials Testing', 'Polycarboxylate Cement', 'Polyurethanes', 'Solubility', 'Sterol Esterase', 'Water'] | 12,742,719 | [['D02.092.146'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G02.380'], ['E05.570'], ['D25.339.291.700', 'J01.637.051.339.291.700'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25.720.327.782', 'D25.720.716.650', 'J01.637.051.720.327.782', 'J01.637.051.720.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Thermospray LC/MS/MS analysis of wastewater for disperse azo dyes. | Primary effluent from a municipal wastewater treatment plant was used as the feed in bench scale activated sludge systems. These systems were spiked with disperse azo dyes at 1 mg 1-1 and 5 mg 1-1 levels and were sampled at various points in the process. Samples were analysed by high performance liquid chromatography w... | ['Azo Compounds', 'Chromatography, High Pressure Liquid', 'Chromatography, Liquid', 'Coloring Agents', 'Mass Spectrometry', 'Ohio', 'Sewage', 'Spectrophotometry, Ultraviolet'] | 2,959,343 | [['D02.172'], ['E05.196.181.400.300'], ['E05.196.181.400'], ['D27.720.233'], ['E05.196.566'], ['Z01.107.567.875.075.512', 'Z01.107.567.875.350.540', 'Z01.107.567.875.510.540'], ['D20.944.932.500'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Leishmania chagasi infection in cats with dermatologic lesions from an endemic area of visceral leishmaniosis in Brazil. | Although dogs are considered the main domestic reservoirs for Visceral Leishmaniosis (VL), which is caused in the Americas by Leishmania chagasi, infected cats have also been recently found in endemic areas of several countries and became a public health concern. Accordingly, the purpose of this study was to evaluate c... | ['Animals', 'Brazil', 'Cat Diseases', 'Cats', 'Endemic Diseases', 'Leishmania', 'Leishmaniasis, Visceral', 'Skin'] | 21,282,011 | [['B01.050'], ['Z01.107.757.176'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['N06.850.392'], ['B01.268.475.868.488'], ['C01.610.752.300.500.510', 'C01.920.813.510'], ['A17.815']] | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Antibiotic treatment of experimental pneumonic plague in mice. | A mouse model was developed to evaluate the efficacy of antibiotic treatment of pneumonic plague; streptomycin was compared to antibiotics with which there is little or no clinical experience. Infection was induced by inhalation of aerosolized Yersinia pestis organisms. Antibiotics were administered by intraperitoneal ... | ['Animals', 'Anti-Bacterial Agents', 'Disease Models, Animal', 'Female', 'Mice', 'Plague', 'Streptomycin', 'Survival Analysis', 'Treatment Outcome'] | 9,517,950 | [['B01.050'], ['D27.505.954.122.085'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.635.505.500'], ['C01.150.252.400.310.980.390', 'C01.920.906'], ['D09.408.051.885'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Analysis of lytic effect on fibrin of immobilized heparin in complex with plasma proteins]. | Reactions of heparin, covalently immobilized in hydrogel, with fibrinolysin, blood serum albumin, thrombin and fibrinogen were studied. All the proteins studied were shown to penetrate into the hydrogel pores and to interact with the immobilized heparin. Stability of the complexes was decreased in the following sequenc... | ['Adsorption', 'Blood Proteins', 'Fibrin', 'Fibrinogen', 'Fibrinolysin', 'Fibrinolysis', 'Heparin', 'Humans', 'In Vitro Techniques', 'Polymers', 'Serum Albumin', 'Thrombin'] | 6,217,639 | [['G01.030', 'G02.020'], ['D12.776.124'], ['D12.776.124.270'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['G09.188.390.150.390'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The impact of prescribed opioids on CD4 cell count recovery among HIV-infected patients newly initiating antiretroviral therapy. | OBJECTIVES: Certain prescribed opioids have immunosuppressive properties, yet their impact on clinically relevant outcomes, including antiretroviral therapy (ART) response among HIV-infected patients, remains understudied.METHODS: Using the Veterans Aging Cohort Study data, we conducted a longitudinal analysis of 4358 ... | ['Adult', 'Analgesics, Opioid', 'Anti-Retroviral Agents', 'CD4 Lymphocyte Count', 'Female', 'HIV Infections', 'Humans', 'Immunosuppressive Agents', 'Longitudinal Studies', 'Male', 'Middle Aged'] | 27,186,715 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D27.505.954.122.388.077'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of glutamate transport substrates and glutamate receptor ligands on the activity of Na-/K(+)-ATPase in brain tissue in vitro. | 1. It has been suggested that Na+/K(+)-ATPase and Na(+)-dependent glutamate transport (GluT) are tightly linked in brain tissue. In the present study, we have investigated Na+/K(+)-ATPase activity using Rb+ uptake by 'minislices' (prisms) of the cerebral cortex. This preparation preserves the morphology of neurons, syn... | ['Amino Acid Transport System X-AG', 'Animals', 'Aspartic Acid', 'Brain', 'Enzyme Inhibitors', 'Excitatory Amino Acid Antagonists', 'Female', 'Glutamic Acid', 'In Vitro Techniques', 'Ionophores', 'Ligands', 'Male', 'Microscopy, Electron', 'Neurotoxins', 'Ouabain', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Glutamate',... | 15,566,390 | [['D12.776.157.530.200.249.500', 'D12.776.157.530.937.250', 'D12.776.543.585.200.249.500', 'D12.776.543.585.937.250'], ['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['A08.186.211'], ['D27.505.519.389'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['D12.125.067.625.349', 'D12.125.11... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vasoactive properties of dihomo-gamma-linolenic acid and series one prostaglandins in a freshwater teleost, Channa maculata. | 1. Prostaglandins A1, B1, E1 and F1 alpha (2-120 micrograms/kg), arachidonic acid and dihomo-gamma-linolenic acid (0.1-2 mg/kg) were injected intravenously into Channa maculata and changes in arterial blood pressure were recorded. 2. Injection of PGF1 alpha had no significant effect on arterial blood pressure. Injectio... | ['8,11,14-Eicosatrienoic Acid', 'Animals', 'Arachidonic Acid', 'Arachidonic Acids', 'Blood Pressure', 'Fatty Acids, Unsaturated', 'Fishes', 'Indomethacin', 'Prostaglandins'] | 2,566,452 | [['D10.251.355.255.207'], ['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D10.251.355'], ['B01.050.150.900.493'], ['D03.633.100.473.420'], ['D10.251.355.255.550', 'D23.469.050.175.725']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons. | BACKGROUND: Lack of appropriate tools and techniques to study fate and functional integration of newly generated neurons has so far hindered understanding of neurogenesis' relevance under physiological and pathological conditions. Current analyses are either dependent on mitotic labeling, for example BrdU-incorporation... | ['Animals', 'Brain Mapping', 'Cell Lineage', 'Gene Expression Regulation, Developmental', 'Integrases', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Microtubule-Associated Proteins', 'Neural Stem Cells', 'Neurogenesis', 'Neuropeptides', 'Stem Cells', 'Tamoxifen', 'Transgenes'] | 21,194,452 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['G05.308.310'], ['D08.811.739.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fossil pollen as a guide to conservation in the Galapagos. | Paleoecological evidence from the past 8000 years in the Gal?pagos Islands shows that six presumed introduced or doubtfully native species (Ageratum conyzoides, Borreria laevis/Diodia radula-type, Brickellia diffusa, Cuphea carthagenensis, Hibiscus diversifolius, and Ranunculus flagelliformis) are in fact native to the... | ['Conservation of Natural Resources', 'Ecology', 'Ecosystem', 'Ecuador', 'Fossils', 'Humans', 'Magnoliopsida', 'Pollen'] | 19,023,075 | [['J01.256', 'N06.230.080'], ['H01.158.273.248', 'H01.277.249'], ['G16.500.275.157', 'N06.230.124'], ['Z01.107.757.362'], ['I01.076.368.584.311'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.650.940.800.575.912.250'], ['A18.024.249.500.249.500']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Clinical effect of a triclosan-containing dentifrice on plaque and gingivitis: a six-month study. | A total of 294 adult male and female subjects completed a 6-month, double-blind clinical trial designed to evaluate the effects of a dentifrice which contained 0.3% triclosan in conjunction with 2% of a methoxyethylene/maleic acid copolymer in a 0.243% sodium fluoride/silica base, relative to a control dentifrice, on s... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Dental Plaque', 'Dental Plaque Index', 'Dentifrices', 'Double-Blind Method', 'Female', 'Gingivitis', 'Humans', 'Longitudinal Studies', 'Male', 'Maleates', 'Middle Aged', 'Periodontal Index', 'Polyvinyls', 'Triclosan'] | 1,298,577 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['D25.376', 'D27.720.269.380', 'J01.637.051.376'], ['E05.318... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Feasibility of small bowel flow rate measurement with MRI. | OBJECTIVE: To evaluate whether it is feasible to measure the segmental flux of small bowel content using MR phase-contrast (PC) pulse sequences.MATERIALS AND METHODS: Using a phantom the accuracy of flux measurements was validated. Afterwards, 10 volunteers were included in a prospective clinical trial. To provide stan... | ['Adult', 'Butylscopolammonium Bromide', 'Female', 'Gadolinium', 'Gastrointestinal Motility', 'Humans', 'Image Processing, Computer-Assisted', 'Intestine, Small', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Parasympatholytics', 'Peristalsis', 'Phantoms, Imaging', 'Time Factors'] | 20,677,261 | [['M01.060.116'], ['D02.092.877.310', 'D02.145.074.722.822.200', 'D03.132.889.601.200', 'D03.605.084.500.722.822.200', 'D03.605.869.822.200'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['G10.261.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A03.556.124.684'], ['E01.370.350.825.500'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Electrophysiologic effects of halothane and quinidine on canine Purkinje fibers: evidence for a synergistic interaction. | The authors studied possible interactions between halothane and quinidine on the action potentials of canine Purkinje fibers superfused with Tyrode's solution. Using standard microelectrode techniques and a physiologic pacing rate (2 Hz), halothane in concentrations from 0.5% to 2% decreased the action potential durati... | ['Action Potentials', 'Animals', 'Dogs', 'Drug Synergism', 'Electric Conductivity', 'Electrophysiology', 'Female', 'Halothane', 'Heart Conduction System', 'Male', 'Membrane Potentials', 'Purkinje Fibers', 'Quinidine'] | 3,752,573 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.968.477'], ['G01.358.500.249.277'], ['H01.158.344.528', 'H01.158.782.236'], ['D02.455.526.340'], ['A07.541.409'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A07.541.409.683'],... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Omega-3 fatty acids and astaxanthin in health and disease. Recent knowledges]. | At present, medicine is aimed to the treatment of lesions. Instead, it would be right to develop the maintenance of normal health. A number of authorities have recently recommended increases in intake of omega-3 fatty acids and astaxanthin for the health of general population. Omega-3 are necessary to provide the optim... | ['Fatty Acids, Omega-3', 'Health Promotion', 'Humans', 'Primary Prevention', 'Xanthophylls'] | 20,540,399 | [['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.758', 'N06.850.780.680'], ['D02.455.326.271.665.202.868', 'D02.455.426.392.368.367.379.249.887', 'D02.455.849.131.868', 'D23.767.261.887']] | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Metastatic signet ring adenocarcinoma: an unusual cause of cardiac constriction. | Pericardial constriction secondary to metastatic adenocarcinoma is exceedingly rare. We present the first recorded case of pericardial constriction secondary to metastatic signet-ring mucinous adenocarcinoma diagnosed by echocardiography. The cornerstones of echocardiographic diagnosis of constriction are the following... | ['Carcinoma, Signet Ring Cell', 'Echocardiography, Doppler, Pulsed', 'Heart Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Pericarditis, Constrictive', 'Risk Assessment', 'Risk Factors'] | 17,117,320 | [['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['E01.370.350.130.750.220.225', 'E01.370.350.850.220.220.225', 'E01.370.350.850.850.220.225', 'E01.370.350.850.850.860.225', 'E01.370.370.380.220.220.225'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cocaine detection in maternal and neonatal hair: implications to fetal toxicology. | Cocaine use during pregnancy is difficult to ascertain, and maternal reports are likely to be inaccurate. Presently, the dose-response characteristics between maternal cocaine use and fetal exposure and adverse effects are unknown. Clinically, some babies are harmed, whereas others are not adversely affected. Taking ad... | ['Cocaine', 'Cocaine-Related Disorders', 'Dose-Response Relationship, Drug', 'Female', 'Hair', 'Humans', 'Infant', 'Infant, Newborn', 'Maternal-Fetal Exchange', 'Meconium', 'Pregnancy', 'Substance Abuse Detection', 'Time Factors'] | 17,304,153 | [['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['C25.775.300', 'F03.900.300'], ['G07.690.773.875', 'G07.690.936.500'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['G08.686.784.769.455'], ['A12.459.529', 'A16.378.529'], ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Forget Me if You Can: Attentional capture by to-Be-remembered and to-Be-forgotten visual stimuli. | Previous studies on directed forgetting in visual working memory (VWM) have shown that, if people are cued to remember only a subset of the items currently held in VWM, they will completely forget the uncued, no longer relevant items. While this finding is indicative of selective remembering, it remains unclear whether... | ['Adult', 'Attention', 'Cues', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Mental Recall', 'Young Adult'] | 28,074,450 | [['M01.060.116'], ['F02.830.104.214'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463.425.540.641'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential diagnosis of genitourinary tumors using monoclonal antibodies to intermediate filament proteins. | Definitive diagnosis of poorly differentiated and metastatic neoplasms may be impossible using conventional histologic criteria. Recent developments in cell biology and immunology now enable us to answer such difficult diagnostic problems. Several varieties of structural proteins can be identified in malignant cells us... | ['Adenocarcinoma', 'Aged', 'Antibodies, Monoclonal', 'Carcinoma, Renal Cell', 'Carcinoma, Squamous Cell', 'Carcinoma, Transitional Cell', 'Female', 'Humans', 'Immunohistochemistry', 'Intermediate Filament Proteins', 'Kidney Neoplasms', 'Male', 'Urogenital Neoplasms'] | 2,775,372 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['C04.557.470.200.400'... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Insecticide resistance mapping in the vector of lymphatic filariasis, Culex quinquefasciatus Say from northern region of West Bengal, India. | Culex quinquefasciatus is a vector of lymphatic filariasis and vector control strategies normally involve the use of synthetic insecticides targeted against them. Extensive and uncontrolled use of these synthetic insecticides has led to the development of insecticide resistance in the mosquito vectors. In this context,... | ['Animals', 'Culex', 'Dengue', 'Disease Vectors', 'Elephantiasis, Filarial', 'India', 'Insect Vectors', 'Insecticide Resistance', 'Insecticides', 'Isoenzymes', 'Malathion', 'Mortality', 'Mosquito Control', 'Mosquito Vectors'] | 31,141,548 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.225'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['N06.850.335.188', 'N06.850.520.203.375'], ['C01.610.335.508.700.750.361.350', 'C01.920.750', 'C15.604.496.490'], ['Z01.252.245.393'], ['N06.850.335.188.100.5... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Diabetes does not affect ventricular repolarization and sudden cardiac death risk in patients with dilated cardiomyopathy. | BACKGROUND: We studied the effects of diabetes on ventricular repolarization parameters and sudden cardiac death in patients with dilated cardiomyopathy (DCM).METHODS: We enrolled 132 consecutive patients in New York Heart Association (NYHA) heart failure functional classes II or III and left ventricular ejection fract... | ['Cardiomyopathy, Dilated', 'Comorbidity', 'Death, Sudden, Cardiac', 'Diabetes Mellitus', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Risk Assessment', 'Slovenia', 'Survival Analysis', 'Survival Rate'] | 19,250,080 | [['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['N05.715.350.225', 'N06.850.490.687'], ['C14.280.383.220', 'C23.550.260.322.250'], ['C18.452.394.750', 'C19.246'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N... | ['Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cerebral hemodynamic changes during plateau waves in brain-tumor patients. | The plateau wave, one of the wave forms observed in patients with increased intracranial pressure, has previously been extensively investigated, but its pathophysiological aspect is as yet unclear. The authors undertook a study of cerebral hemodynamic changes while the plateau waves were observed in five brain-tumor pa... | ['Adult', 'Blood Pressure', 'Brain Neoplasms', 'Carbon Dioxide', 'Cerebrovascular Circulation', 'Female', 'Humans', 'Intracranial Pressure', 'Male', 'Middle Aged', 'Partial Pressure', 'Vascular Resistance', 'Vasodilation'] | 423,003 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early Miocene amber inclusions from Mexico reveal antiquity of mangrove-associated copepods. | Copepods are aquatic microcrustaceans and represent the most abundant metazoans on Earth, outnumbering insects and nematode worms. Their position of numerical world predominance can be attributed to three principal radiation events, i.e. their major habitat shift into the marine plankton, the colonization of freshwater... | ['Amber', 'Animals', 'Biological Evolution', 'Copepoda', 'Ecosystem', 'Fossils', 'Mexico', 'Plankton', 'Symbiosis', 'Wetlands'] | 27,731,321 | [['D05.750.078.840.109', 'D20.215.721.500.109'], ['B01.050'], ['G05.045', 'G16.075'], ['B01.050.500.131.365.160'], ['G16.500.275.157', 'N06.230.124'], ['I01.076.368.584.311'], ['Z01.107.567.589'], ['B05.080.500'], ['G06.550.800', 'G16.840'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
BMI change following spinal fusion for neuromuscular scoliosis surgery. | STUDY DESIGN: Retrospective descriptive, multi-center study.OBJECTIVES: We hypothesize that a post-operative weight gain will result in patients who are underweight prior to surgery. Cachexia and low body mass index is common among children with cerebral palsy (CP). Many interventions are undertaken to assist the child... | ['Adolescent', 'Body Mass Index', 'Body Weight', 'Cerebral Palsy', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Postoperative Period', 'Retrospective Studies', 'Scoliosis', 'Spinal Fusion', 'Time Factors', 'Treatment Outcome', 'Weight Gain'] | 32,394,323 | [['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C10.228.140.140.254'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.45... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Overt motor preparation in choice-reaction time task. | In a serial pointing task to three unequidistant, unequiprobable targets, the moving picture record of the subject's hand movements shows, before each pointing movement, a repositioning of the hand near the median plane of the working panel when the subject sees the targets and near the more frequently used target when... | ['Hand', 'Humans', 'Movement', 'Proprioception', 'Reaction Time', 'Task Performance and Analysis', 'Visual Perception'] | 740,500 | [['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['F02.830.816.541', 'G07.888.750', 'G11.561.790.541'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['F02.463.593.932']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Computer evaluation of sleep. | Night sleep registrations were carried out using a portable 4-channel tape recorder (Medilog 4-24 recorder). The evaluation of the sleep stages was done by a computer analysis. One channel was used for EMG, 1 for EOG and 2 channels for EEG. For the analysis of the particular sleep stages the criteria of the Florida mod... | ['Ambulatory Care', 'Electroencephalography', 'Electromyography', 'Electronic Data Processing', 'Electrooculography', 'Humans', 'Microcomputers', 'Sleep', 'Sleep Stages'] | 3,758,124 | [['E02.760.106', 'N02.421.585.106'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.405.255', 'E01.370.530.255'], ['L01.224.085'], ['E01.370.380.230.285', 'E01.370.405.245.787.285'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.260.550'], ['F02.830.855', 'G11.561.803'], ['F02.830.855.796', 'G11.561... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Llama medicine. Obstetrics, neonatal care, and congenital conditions. | Obstetrical care of the llama is very similar to other food animal and equine obstetrics. Understanding the few unique llama characteristics such as birthing from a standing position, no licking of the neonate by the mother, and the epidermal membrane covering the newborn, help give confidence when treating llamas. Dys... | ['Agammaglobulinemia', 'Animals', 'Animals, Newborn', 'Artiodactyla', 'Camelids, New World', 'Female', 'Immunity, Maternally-Acquired', 'Labor, Obstetric', 'Obstetric Labor Complications', 'Pregnancy'] | 2,784,346 | [['C15.378.147.142', 'C15.604.515.032', 'C20.673.088'], ['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.500'], ['B01.050.150.900.649.313.500.190.090'], ['G12.450.570'], ['G08.686.784.769.326'], ['C13.703.420'], ['G08.686.784.769']] | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arterial occlusion in nephrotic syndrome: report of four cases in Siriraj Hospital. | Venous thrombosis is commonly found in nephrotic syndrome, but arterial occlusion is never report in Thailand. Four cases with cerebral and femoral arteries occlusion were demonstrated. The early diagnosis and appropriate intervention can improve outcomes, reduce mortality and morbidity significantly. | ['Adult', 'Arterial Occlusive Diseases', 'Hospitals, University', 'Humans', 'Male', 'Middle Aged', 'Nephrotic Syndrome', 'Thailand', 'Thrombosis'] | 19,562,995 | [['M01.060.116'], ['C14.907.137'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.777.419.630.643', 'C13.351.968.419.630.643'], ['Z01.252.145.841'], ['C14.907.355.830']] | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Vascular changes in irradiated lungs: a morphometric study. | The lungs from eight patients who had received thoracic irradiation for the treatment of malignant disease have been studied and a morphometric analysis of the vascular changes present has been made. We found a marked difference between the changes we observed in the pulmonary vessels and those described in systemic ve... | ['Humans', 'Pulmonary Artery', 'Pulmonary Circulation', 'Pulmonary Veins', 'Radiography, Thoracic', 'Thoracic Neoplasms'] | 2,769,484 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.715'], ['G09.330.100.770', 'G09.772.593'], ['A07.015.908.713'], ['E01.370.350.700.730'], ['C04.588.894']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Use of DNA polymorphism in forensic paternity evaluation]. | Problematical paternity cases were additionally subjected to DNA-polymorphism analysis. 5 cases are reported, focusing on problems due to, 'silent' allele transmittance, relatively low probability for paternity, obvious occurrence of the extremely rare Rh gene complex CWc, involvement of brothers as putative fathers, n... | ['Adult', 'Blood Group Antigens', 'Child', 'Chromosome Mapping', 'DNA', 'DNA Probes', 'Female', 'Gene Frequency', 'HLA Antigens', 'Humans', 'Male', 'Paternity', 'Phenotype', 'Polymorphism, Genetic', 'Polymorphism, Restriction Fragment Length', 'Rh-Hr Blood-Group System'] | 1,969,686 | [['M01.060.116'], ['D23.050.301.290', 'D23.050.705.230'], ['M01.060.406'], ['E05.393.183'], ['D13.444.308'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['G05.330'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.198.780.937.766'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Guidewire navigation in coronary artery stenoses using a novel magnetic navigation system: first clinical experience. | The objective of this study was to investigate the efficacy of guidewire navigation across coronary artery stenoses using magnetic navigation system (MNS) versus conventional navigation. The MNS is a novel option to facilitate access to target lesions, particularly in tortuous vessels. In an experimental study using a ... | ['Angioplasty, Balloon, Coronary', 'Coronary Angiography', 'Coronary Stenosis', 'Equipment Design', 'Fluoroscopy', 'Humans', 'Magnetics', 'Phantoms, Imaging', 'Statistics, Nonparametric', 'User-Computer Interface'] | 16,489,562 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Clinical treatment observation of tea pigment for oral submucous fibrosis]. | 39 patients with oral submucous fibrosis (OSF) were divided into control and experimental groups. The control group included 22 OSF patients who were treated by oral administration of VitAD, VitBco and VitE, and the experimental group included 17 OSF patients who were treated with vitamins and tea pigment after their e... | ['Adult', 'Camellia sinensis', 'Female', 'Hemorheology', 'Humans', 'Male', 'Middle Aged', 'Oral Submucous Fibrosis', 'Pigments, Biological', 'Tea'] | 12,078,186 | [['M01.060.116'], ['B01.650.940.800.575.912.250.341.998.500.500'], ['E05.830.250', 'G09.188.370', 'G09.330.380.630'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.654'], ['D23.767'], ['D20.215.784.844', 'G07.203.100.831', 'J02.200.831']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
[Incidental findings of expansive processes in the sellar region]. | The technologic advancement of imaging techniques especially computed tomography (CT) and magnetic resonance (MRI) is associated with an increasing number of incidentally discovered sellar masses. The endocrinologists are facing the problem to distinguish between benign and clinically often insignificant non-functionin... | ['Brain Diseases', 'Humans', 'Incidental Findings', 'Magnetic Resonance Imaging', 'Pituitary Diseases', 'Pituitary Neoplasms', 'Sella Turcica', 'Tomography, X-Ray Computed'] | 12,693,292 | [['C10.228.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.410'], ['E01.370.350.825.500'], ['C10.228.140.617.738', 'C19.700'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C10.228.140.211.885.500.600', 'C10.228.140.617.477.600', 'C10.228.140.617.738.675', 'C10.551.240.250.700.500.500', 'C19.344... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Breast tenderness and breast cancer risk in the estrogen plus progestin and estrogen-alone women's health initiative clinical trials. | The associations between breast tenderness during use of conjugated equine estrogen (CEE) therapy with or without medroxyprogesterone (MPA) therapy and subsequent breast cancer risk are unknown. We analyzed data from the Women's Health Initiative Estrogen plus Progestin (N = 16,608, 5.6 years intervention) and estrogen... | ['Aged', 'Breast Neoplasms', 'Drug Combinations', 'Estrogen Replacement Therapy', 'Estrogens, Conjugated (USP)', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Mastodynia', 'Medroxyprogesterone', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Invasiveness', 'Prevalence', 'Proportional Hazards Models'] | 22,042,371 | [['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['D26.310'], ['E02.319.452.150'], ['D06.472.334.851.437.988'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['C23.888.592.612.530', 'F02.830.816.308', 'G11.561.790.308'], ['D04.21... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The influence of age and gender on haematological parameters in Lipizzan horses. | Haematological parameters [red blood cell count (RBC), white blood cell count (WBC), packed cell volume (PCV), haemoglobin concentration, mean cell volume (MCV), mean cell haemoglobin (MCH) and mean cell haemoglobin concentration (MCHC)] in resting Lipizzan horses were determined for 143 stallions, 104 mares and 25 foa... | ['Age Factors', 'Aging', 'Animals', 'Breeding', 'Female', 'Hematologic Tests', 'Horses', 'Male', 'Reference Values', 'Sex Characteristics'] | 12,069,265 | [['N05.715.350.075', 'N06.850.490.250'], ['G07.345.124'], ['B01.050'], ['E05.820.150', 'G05.090'], ['E01.370.225.625', 'E05.200.625'], ['B01.050.150.900.649.313.984.235.472'], ['E05.978.810'], ['G08.686.815']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Expanded progeny cells of diffuse cytotoxic bone marrow-derived colonies. | Bone marrow-derived (colony-stimulating factor [CSF]-dependent) diffuse colonies have been shown to include colonies with cytotoxic activity. Such diffuse colonies were expanded for 6-8 weeks in liquid culture medium in the presence of pokeweed mitogen- or concanavalin A-conditioned spleen cell medium (CM). The morphol... | ['Animals', 'Bone Marrow', 'Bone Marrow Cells', 'Concanavalin A', 'Culture Media', 'Cytotoxicity, Immunologic', 'Dose-Response Relationship, Immunologic', 'Hematopoiesis', 'Hematopoietic Stem Cells', 'Interferons', 'Mice', 'Mice, Inbred BALB C', 'Pokeweed Mitogens', 'Rats', 'Tetradecanoylphorbol Acetate'] | 6,186,013 | [['B01.050'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D27.720.470.305', 'E07.206'], ['G12.287'], ['G12.300'], ['G04.152.825', 'G09.188.343'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['B01... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Status of the osteoclast-activating system in cosmonauts after long-duration missions to the International Space Station]. | The results of studying the system of osteoprotegerin/ receptor activator of nuclear factor kappa-B ligand (OPG/RANKL) in 22 cosmonauts after long-duration (124 to 199 days) ISS missions are presented. Immediately on return to 1 g, changes were observed in OPG and RANKL serum levels and the ability to produce unstimula... | ['Aerospace Medicine', 'Astronauts', 'Humans', 'Leukocytes, Mononuclear', 'Osteoclasts', 'Osteoprotegerin', 'RANK Ligand', 'Space Flight'] | 25,928,978 | [['H02.403.029'], ['M01.526.173'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['A11.329.372.700', 'A11.627.482.700'], ['D12.776.543.750.705.852.760.949.249'], ['D12.644.276.374.750.562', 'D12.776.467.374.750.562', 'D23.529.374.750.562'], ['J01.937.285... | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 |
Experimental study on repair of the facial nerve with Schwann cells transfected with GDNF genes and PLGA conduits. | CONCLUSIONS: Schwann cells transfected by GDNF genes + PLGA were superior to Schwann cells + PLGA and direct anastomesis. This is a new and effective strategy for repair of facial nerve defects.OBJECTIVE: To evaluate the effect of bioactive artificial nerve conduits in the repair of facial nerve defects in Sprague-Dawl... | ['Action Potentials', 'Animals', 'Cells, Cultured', 'Facial Nerve', 'Facial Nerve Injuries', 'Female', 'Glial Cell Line-Derived Neurotrophic Factor', 'Guided Tissue Regeneration', 'Lactic Acid', 'Male', 'Nerve Regeneration', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Rats', 'Rats, Sprague-Dawl... | 18,607,939 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A11.251'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['C07.465.299.500', 'C10.292.200.500', 'C10.292.319.500', 'C10.900.300.218.300', 'C26.915.300.400.300'], ['D12.644.276.860.381.500', 'D12.776.46... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Clinician-child discourse: some preliminary questions. | Various pragmatic procedures were used to analyze clinician-child discourse in a language remediation setting. Communicative acts, responses to prior requests, and discourse topics were described in the interaction between clinician and child. Three major trends were derived from the data. First, consistent patterns we... | ['Child', 'Child, Preschool', 'Communication', 'Humans', 'Language', 'Professional-Patient Relations', 'Speech Therapy', 'Surveys and Questionnaires', 'Verbal Behavior'] | 661,250 | [['M01.060.406'], ['M01.060.406.448'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F01.829.401.650', 'N05.300.660'], ['E02.760.169.063.500.727.552', 'E02.831.727.552'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['F01.145.209.908... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Dosimetric comparison of treatment plans of pancreatic carcinoma treated with body gamma knife and tomotherapy]. | Fourteen patients with pancreatic carcinoma were selected. Two treatment plans were designed for each patient, including gamma knife and Tomotherapy. The dose characteristics were evaluated by DVH and were compared. The results showed that the gamma knife plan had the higher maximal and mean target dose than Tomotherap... | ['Humans', 'Pancreatic Neoplasms', 'Radiosurgery', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted'] | 24,015,625 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development and psychometric properties of the 12-item diabetes fatalism scale. | OBJECTIVE: This study describes the development and validation of the Diabetes Fatalism Scale (DFS) in adults with type 2 diabetes.METHODS: Thirty-five items were derived from focus groups, literature review, and expert opinion. The items were pilot tested on 20 adults with diabetes and then administered to 216 primary... | ['Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Diabetes Mellitus, Type 2', 'Female', 'Focus Groups', 'Humans', 'Male', 'Middle Aged', 'Pilot Projects', 'Psychometrics', 'Quality of Life', 'Reproducibility of Results', 'Severity of Illness Index'] | 19,908,102 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Occult lead intoxication as a cause of hypertension and renal failure. | BACKGROUND: The true incidence of lead (Pb) overload as a cause of chronic renal failure (CRF) is unknown. Also, it is unclear if CRF per se could generate an increment in the body Pb burden. Most studies of chronic Pb intoxication have been performed on cohorts or patients with a past history of occupational exposure.... | ['Body Burden', 'Bone and Bones', 'Chelating Agents', 'Edetic Acid', 'Gout', 'Humans', 'Hypertension', 'Kidney Failure, Chronic', 'Lead', 'Lead Poisoning', 'Middle Aged'] | 8,918,621 | [['E05.799.638.231', 'N06.850.460.200'], ['A02.835.232', 'A10.165.265'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['C05.550.114.423', 'C05.550.354.500', 'C05.799.414', 'C16.320.565.798.368', 'C18.452.648.798.368'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sexual dimorphism of pancreatic gene expression in normal mice. | A differential pancreatic behavior observed between male and female mice in diabetes and pancreatitis led us to study the gene and protein expressions of endocrine and exocrine pancreatic proteins in normal mice. We compared the levels of expression of six pancreatic genes and of four of the corresponding proteins in m... | ['Amylases', 'Animals', 'Chymotrypsinogen', 'Female', 'Gene Expression Regulation', 'Lipase', 'Male', 'Mice', 'Pancreas', 'RNA, Messenger', 'Rats', 'Sex Characteristics', 'Trypsinogen'] | 11,075,996 | [['D08.811.277.450.066'], ['B01.050'], ['D08.622.184', 'D12.776.811.243.184'], ['G05.308'], ['D08.811.277.352.100.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['A03.734'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['G08.686.815'], ['D08.622.885', 'D12.776.811.243.885']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Family Environment and Childhood Obesity: A New Framework with Structural Equation Modeling. | The main purpose of the current article is to introduce a framework of the complexity of childhood obesity based on the family environment. A conceptual model that quantifies the relationships and interactions among parental socioeconomic status, family food security level, child's food intake and certain aspects of pa... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Body Weight', 'Child', 'Child Behavior', 'Child, Preschool', 'China', 'Eating', 'Feeding Behavior', 'Female', 'Health Behavior', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Models, Theoretical', 'Parent-Child Relations', 'Parents', 'Pediatric Obes... | 28,208,833 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['F01.145.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Transcripts of soybean isoflavone 7-O-glucosyltransferase and hydroxyisoflavanone dehydratase gene homologues are at least as abundant as transcripts of their well known counterparts. | The enzymes of the isoflavonoid pathway produce isoflavones, which have multiple functions in defence and symbiosis. Recently, we identified known and novel homologues of several of these enzymes in the soybean genome sequence. In the present study, we have investigated the transcript levels of the isoflavone 7-O-gluco... | ['Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Glucosyltransferases', 'Hydro-Lyases', 'Plant Proteins', 'RNA', 'RNA, Plant', 'Seedlings', 'Soybeans'] | 21,741,851 | [['G05.308.320'], ['G05.308.375'], ['D08.811.913.400.450.460'], ['D08.811.520.241.300'], ['D12.776.765'], ['D13.444.735'], ['D13.444.735.635'], ['A18.550', 'B01.650.819'], ['B01.650.940.800.575.912.250.401.750']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of REV-ERB alpha gene polymorphisms on obesity phenotypes in adult and adolescent samples. | BACKGROUND: REV-ERBá has been shown to regulate adipogenesis and lipid metabolism as well as to link the circadian timing system to whole body metabolic homeostasis. We thus tested whether polymorphisms in REV-ERBá could be associated with metabolic phenotypes in human population samples.METHODS: We analyzed the associ... | ['Adolescent', 'Adult', 'Anthropometry', 'Blood Glucose', 'Body Mass Index', 'Child', 'Circadian Rhythm', 'Europe', 'Female', 'Gene Expression Regulation', 'Gene Regulatory Networks', 'Humans', 'Insulin', 'Lipids', 'Male', 'Middle Aged', 'Nuclear Receptor Subfamily 1, Group D, Member 1', 'Obesity', 'Odds Ratio', 'Pheno... | 22,828,941 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['G07.180.562.190'], ['Z01.542'], ['G05.308'], ['G05.360.080.689.360'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Atomistic molecular dynamics simulations of peptide amphiphile self-assembly into cylindrical nanofibers. | Relaxation of a self-assembled structure of 144 peptide amphiphile (PA) molecules into cylindrical nanofibers is studied using atomistic molecular dynamics simulations including explicit water with physiological ion concentration. The PA for these studies includes a hydrophobic alkyl chain that is attached to the N-ter... | ['Molecular Dynamics Simulation', 'Nanofibers', 'Peptides', 'Protein Conformation', 'Surface-Active Agents'] | 21,341,770 | [['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['J01.637.512.300'], ['D12.644'], ['G02.111.570.820.709'], ['D27.720.877']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Comparison of two preoperative protocols for mandibular symphyseal distraction osteogenesis to reduce the risk of tooth damage. | Two techniques to separate the lower incisors prior to mandibular symphyseal distraction osteogenesis (MSDO) were evaluated with respect to avoiding tooth damage.METHODS: Fifty patients (20.2 ± 7.0 years) requiring MSDO were treated with a tooth-borne appliance by utilizing two preoperative protocols to separate the ce... | ['Adolescent', 'Adult', 'Child', 'Clinical Protocols', 'Female', 'Humans', 'Incisor', 'Intraoperative Complications', 'Male', 'Mandible', 'Osteogenesis, Distraction', 'Preoperative Care', 'Risk Factors', 'Tooth Injuries', 'Young Adult'] | 28,189,490 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E02.183', 'N05.715.360.330.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.860.425'], ['C23.550.505'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['E04.555.120.690'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795'], ['E05.318.740.600.800... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The FeoC protein leads to high cellular levels of the Fe(II) transporter FeoB by preventing FtsH protease regulation of FeoB in Salmonella enterica. | In the gammaproteobacteria, the FeoA, FeoB, and FeoC proteins constitute the Feo system, which mediates ferrous iron [Fe(II)] import. Of these Feo proteins, FeoB is an inner membrane Fe(II) transporter that is aided by the small protein FeoA. However, the role of another small protein, FeoC, has remained unknown. Here ... | ['ATP-Dependent Proteases', 'Cation Transport Proteins', 'Gene Expression Regulation, Bacterial', 'Iron', 'Salmonella typhimurium', 'Transcription Factors'] | 23,708,131 | [['D08.811.277.040.013.500.032', 'D08.811.277.040.025.024.032', 'D08.811.277.656.149', 'D12.776.157.025.750.032'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['G05.308.300'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760'], ['D12.776... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Converging semantic and phonological information in lexical retrieval and selection in young and older adults. | The present experiments investigated the influence of combined phonological and semantic information on lexical retrieval, metacognitive retrieval states, and selection in an immediate multiple-choice task. Younger and older adults attempted to retrieve words (e.g., abdicate) from low-frequency word definitions. Retrie... | ['Adult', 'Aged', 'Aging', 'Female', 'Humans', 'Male', 'Mental Recall', 'Phonetics', 'Psycholinguistics', 'Semantics', 'Young Adult'] | 30,883,167 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['L01.559.598.518'], ['F02.694', 'F04.096.586', 'L01.559.598.628'], ['L01.559.598.745'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A monoclonal inhibition enzyme immunoassay for detection of antibodies against hepatitis B core antigen: confirmation of an immunodominant epitope. | Monoclonal antibodies (mAbs) were raised against hepatitis B virus core produced by a recombinant clone of Escherichia coli (rHBc). The three mAbs recognized rHBc by Western blot, suggesting that they reacted with non-conformational epitopes. Competition experiments between mAbs and human anti-HBc sera confirmed the ex... | ['Animals', 'Antibodies, Monoclonal', 'Binding, Competitive', 'Blotting, Western', 'Hepatitis B Antibodies', 'Hepatitis B Core Antigens', 'Humans', 'Immunodominant Epitopes', 'Immunoenzyme Techniques', 'Immunoglobulin M', 'Mice', 'Mice, Inbred BALB C'] | 7,929,851 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.79... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of an online orientation course for preceptors in a dedicated education unit program. | The dedicated education unit (DEU) is an emerging model of nursing education. Instead of an instructor-led clinical group, students are partnered with a unit staff nurse for precepted learning. These experiences in learning typically begin with early clinical courses. Precepting nursing students in a DEU is different f... | ['Computer-Assisted Instruction', 'Education, Nursing, Continuing', 'Humans', 'Inservice Training', 'Internet', 'Preceptorship', 'Program Development'] | 23,799,790 | [['I02.903.771.500.208'], ['I02.358.212.450', 'I02.358.462.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['L01.224.230.110.500'], ['I02.358.968'], ['N04.452.760']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Squid neurofilaments. Phosphorylation and Ca2+-dependent proteolysis in situ. | Three major polypeptides co-purify with neurofilaments from squid (Loligo forbesi) axoplasm: P60 (apparent Mr 60,000), P200 (apparent Mr 200,000) and Band 1 (apparent Mr 400,000). Anti-IFA, a monoclonal antibody that recognizes an epitope common to all classes of intermediate filaments, binds to P200 and P60. When axop... | ['Animals', 'Binding Sites', 'Calcium', 'Cytoskeleton', 'Decapodiformes', 'Electrophoresis, Polyacrylamide Gel', 'Immunoelectrophoresis', 'Intermediate Filaments', 'Microscopy, Electron', 'Nerve Tissue Proteins', 'Peptide Fragments', 'Phosphorylation'] | 3,800,978 | [['B01.050'], ['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.430.214.190.750'], ['B01.050.500.644.116.150'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.812.735.645.350.350', 'E05.196.401.568', 'E05.200.812.735.645.350.350', 'E05.301.300.568', 'E05.478.594.760.645.350.35... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postpartum ovarian vein thrombosis. | BACKGROUND: Ovarian vein thrombosis (OVT) is a rare but potentially serious postpartum complication, which occurs in 0.05% to 0.18% of pregnancies and is diagnosed on the right side in 80% to 90% of the cases.CASE REPORT: A 32-year-old woman presented at 15 days postpartum to our emergency department with severe abdomi... | ['Adult', 'Endosonography', 'Female', 'Humans', 'Ovary', 'Puerperal Disorders', 'Tomography, X-Ray Computed', 'Ultrasonography, Doppler, Color', 'Venous Thrombosis'] | 21,902,992 | [['M01.060.116'], ['E01.370.350.850.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['C13.703.844'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['E01.370.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Endotoxemia Induces IêBâ/NF-êB-Dependent Endothelin-1 Expression in Hepatic Macrophages. | Elevated serum concentrations of the vasoactive protein endothelin-1 (ET-1) occur in the setting of systemic inflammatory response syndrome and contribute to distal organ hypoperfusion and pulmonary hypertension. Thus, understanding the cellular source and transcriptional regulation of systemic inflammatory stress-indu... | ['Animals', 'Cell Line', 'Endothelin-1', 'Endotoxemia', 'Gene Expression Regulation', 'I-kappa B Proteins', 'Liver', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred ICR', 'Mice, Transgenic', 'NF-kappa B', 'Signal Transduction'] | 26,342,031 | [['B01.050'], ['A11.251.210'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['C01.757.100.275', 'C01.861.375', 'C23.550.470.790.500.100.275'], ['G05.308'], ['D12.644.360.365', 'D12.776.260.420', 'D12.776.476.381', 'D12.776.930.326'], ['A03.620'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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