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Clinical results following enlargement of the cervical spinal canal by means of laminoplasty. | Since 1978, cervical spinal canal laminoplasty has been performed on 75 patients in our hospital with cervical radiculomyelopathy and followed with studies of from 6 months to 8 years (average 4 years and 6 months). Overall results: the pre-operative score, using the Japanese Orthopaedic Association Scoring System, was... | ['Female', 'Follow-Up Studies', 'Humans', 'Laminectomy', 'Middle Aged', 'Radiography', 'Spinal Canal', 'Spinal Stenosis'] | 3,249,098 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['M01.060.116.630'], ['E01.370.350.700'], ['A02.835.232.834.803'], ['C05.116.900.825']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
KLF4-Mediated CDH3 Upregulation Suppresses Human Hepatoma Cell Growth and Migration via GSK-3â Signaling. | P-cadherin (CDH3), a classical cell adhesion molecule involved in tissue integrity and cell localization, has been implicated in many types of cancer. However, little is known about its function and regulatory mechanism in hepatocellular carcinoma (HCC). Here we report that CDH3 was positively regulated by kr¨uppel-lik... | ['Blotting, Western', 'Cadherins', 'Carcinoma, Hepatocellular', 'Cell Movement', 'Cell Proliferation', 'Gene Expression Regulation, Neoplastic', 'Glycogen Synthase Kinase 3 beta', 'Humans', 'Immunohistochemistry', 'Kruppel-Like Transcription Factors', 'Liver Neoplasms', 'Signal Transduction', 'Tissue Array Analysis'] | 31,182,916 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Motor activity and tonic heart rate in panic disorder. | Motor activity and tonic heart rate were monitored in 62 drug-free panic disorder patients and 40 normal control subjects. Mean daily activity, mean waking heart rate controlled for activity, and mean sleeping heart rate were determined. Panic disorder patients without phobic avoidance showed higher activity than contr... | ['Adult', 'Anxiety Disorders', 'Arousal', 'Electrocardiography, Ambulatory', 'Fear', 'Female', 'Heart Rate', 'Humans', 'Male', 'Motor Activity', 'Panic', 'Phobic Disorders'] | 2,349,312 | [['M01.060.116'], ['F03.080'], ['F02.830.104', 'G11.561.035'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['F01.470.361'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['F01.470.361.585'], ['F03.080.725']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Universal Mental Health Promotion Programme for Young People in Italy. | In Italy, the Mental Health Unit of the National Institute of Public Health has developed a school-based mental health programme based on a structured handbook. The aim of this programme is to promote self-efficacy, psychological well-being, and life satisfaction. In this study, we evaluated the effectiveness of this p... | ['Adolescent', 'Adolescent Health', 'Female', 'Health Promotion', 'Humans', 'Italy', 'Male', 'Mental Health', 'Personal Satisfaction', 'Random Allocation', 'Self Efficacy'] | 26,380,271 | [['M01.060.057'], ['N01.400.075'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['F02.418', 'N01.400.500'], ['F01.145.677'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['F01.752.747.792.700']] | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Blockade of human group X secreted phospholipase A2 (GX-sPLA2)-induced airway inflammation and hyperresponsiveness in a mouse asthma model by a selective GX-sPLA2 inhibitor. | Group X (GX) phospholipase A(2), a member of a large group of secreted phospholipases A(2) (sPLA(2)s), has recently been demonstrated to play an important in vivo role in the release of arachidonic acid and subsequent formation of eicosanoids. In a Th2 cytokine-driven mouse asthma model, deficiency of mouse GX (mGX)-sP... | ['Allergens', 'Animals', 'Asthma', 'Disease Models, Animal', 'Enzyme Inhibitors', 'Gene Knock-In Techniques', 'Group X Phospholipases A2', 'Humans', 'Inflammation', 'Mice', 'Mice, Knockout', 'Mucus'] | 21,652,694 | [['D23.050.063'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.519.389'], ['E05.393.335.249'], ['D08.811.277.352.100.680.750.937.750.887'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['B01.050.150.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictive Ability of Future Anxiety in Professional Decision-Making Skill among a Syrian Refugee Adolescent in Jordan. | This study aimed to examine how and to what extent future anxiety contributes to the level of professional decision-making skills among Syrian refugee students in the tenth grade in public schools in Jordan for the year 2018/2019. Using a quantitative approach, 227 tenth-grade Syrian refugee students in public schools ... | ['Adolescent', 'Anxiety', 'Female', 'Humans', 'Jordan', 'Male', 'Occupational Therapy', 'Professional Role', 'Refugees', 'Students', 'Syria', 'Universities'] | 32,292,305 | [['M01.060.057'], ['F01.470.132'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.400'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['F01.829.316.616.625'], ['M01.755'], ['M01.848'], ['Z01.252.245.500.795'], ['I02.783.830', 'J03.832.830']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 |
Structural and functional study of a conserved region in the uncoupling protein UCP1: the three matrix loops are involved in the control of transport. | It has been reported that the region 261-269 of the uncoupling protein from brown adipose tissue mitochondria, UCP1, has an important role in the control of its proton translocating activity. Thus the deletion of residues Phe267-Lys268-Gly269 leads to the loss of the nucleotide regulation of the protein, while the comp... | ['Adipose Tissue', 'Amino Acid Sequence', 'Animals', 'Binding Sites', 'Carrier Proteins', 'Circular Dichroism', 'Ion Channels', 'Magnetic Resonance Spectroscopy', 'Membrane Proteins', 'Mitochondria', 'Mitochondrial Proteins', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Nucleotides', '... | 10,493,863 | [['A10.165.114'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['D12.776.157'], ['E05.196.867.151'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['E05.196.867.519'], ['D12.776.543'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D12.776.575'], ['E05.59... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Defining the boundaries and characterizing the landscape of functional genome expression in vascular tissues of Populus using shotgun proteomics. | Current state-of-the-art experimental and computational proteomic approaches were integrated to obtain a comprehensive protein profile of Populus vascular tissue. This featured: (1) a large sample set consisting of two genotypes grown under normal and tension stress conditions, (2) bioinformatics clustering to effectiv... | ['Amino Acid Sequence', 'Cell Wall', 'Computational Biology', 'Gene Expression', 'Gene Expression Regulation, Plant', 'Genome, Plant', 'Molecular Sequence Data', 'Peptide Fragments', 'Peptide Mapping', 'Plant Proteins', 'Plant Vascular Bundle', 'Polymorphism, Single Nucleotide', 'Populus', 'Proteolysis', 'Proteome', 'P... | 22,003,893 | [['G02.111.570.060', 'L01.453.245.667.060'], ['A11.284.183'], ['H01.158.273.180', 'L01.313.124'], ['G05.297'], ['G05.308.375'], ['G05.360.340.365'], ['L01.453.245.667'], ['D12.644.541'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['D12.776.765'], ['A18.450'], ['G05.365.795... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Disseminated tuberculosis, bone marrow necrosis and lymphoma: a case report. | Tuberculosis often complicates lymphoma, and bone marrow necrosis has been described in disseminated tuberculosis. However, the association of lymphoma, disseminated tuberculosis and bone marrow necrosis is rare. We report a patient with this triple association. After a 3-week influenza-like illness the patient was adm... | ['Adult', 'Bone Marrow', 'Bone Marrow Diseases', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Necrosis', 'Tuberculosis, Miliary'] | 579,679 | [['M01.060.116'], ['A15.382.216'], ['C15.378.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['C23.550.717'], ['C01.150.252.410.040.552.846.764']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of man-made structures on sedimentary oxygenation: extent, seasonality and implications for offshore renewables. | The number of man-made structures to be placed in the marine environment is set to increase massively in the near future as a consequence of the wide-scale adoption and commercialisation of offshore electricity generation. Marine renewable energy devices (MREDs) interact with their receiving environment and are de-fact... | ['Aquatic Organisms', 'Biomass', 'Conservation of Energy Resources', 'Ecosystem', 'Environmental Monitoring', 'Geologic Sediments', 'Oxidation-Reduction', 'Oxygen', 'Scotland', 'Seasons', 'Wind'] | 24,582,510 | [['B05.080', 'G16.500.275.725.500.650.075'], ['G16.500.275.157.100', 'N06.230.124.100'], ['N06.230.080.078'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670'], ['Z01.542.363.766'], ['G01.910.645... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effect of a combination of genistein, polyunsaturated fatty acids and vitamins D3 and K1 on bone mineral density in postmenopausal women: a randomized, placebo-controlled, double-blind pilot study. | PURPOSE: Many postmenopausal women desire non-pharmaceutical alternatives to hormone therapy for protection against osteoporosis. Soybean isoflavones, especially genistein, are being studied for this purpose. This study examined the effects of synthetic genistein in combination with other potential bone-protective diet... | ['Bone Density', 'Bone Resorption', 'Calcium, Dietary', 'Cholecalciferol', 'Double-Blind Method', 'Fatty Acids, Unsaturated', 'Female', 'Femur', 'Femur Neck', 'Genistein', 'Humans', 'Lumbar Vertebrae', 'Middle Aged', 'Motor Activity', 'Osteoporosis, Postmenopausal', 'Patient Compliance', 'Pilot Projects', 'Vitamin K 1'... | 22,302,614 | [['G11.427.100'], ['C05.116.264', 'G11.427.213.150'], ['D01.146.395'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D10.251.355'], ['A02.835.232.043.150'], ['A02.835.232.043.1... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Single-cell damage elicits regional, nematode-restricting ethylene responses in roots. | Plants are exposed to cellular damage by mechanical stresses, herbivore feeding, or invading microbes. Primary wound responses are communicated to neighboring and distal tissues by mobile signals. In leaves, crushing of large cell populations activates a long-distance signal, causing jasmonate production in distal orga... | ['Animals', 'Arabidopsis', 'Calcium Signaling', 'Cyclopentanes', 'Ethylenes', 'Host-Parasite Interactions', 'Nematoda', 'Oxylipins', 'Plant Roots', 'Plants, Genetically Modified', 'Reactive Oxygen Species', 'Single-Cell Analysis', 'Stress, Mechanical', 'Stress, Physiological', 'Time-Lapse Imaging'] | 31,061,171 | [['B01.050'], ['B01.650.940.800.575.912.250.157.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D02.455.426.392.368.450'], ['D02.455.326.271.367'], ['G16.527.200.400'], ['B01.050.500.500.294'], ['D10.251.355.645'], ['A18.400'], ['B01.650.520', 'B05.620.600'], ['D01.339.431', 'D01.650.775'], ['E0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An evaluation of the impact of a tracheostomy weaning protocol on extubation time. | BACKGROUND: To avoid the possible complications of prolonged intubation, it is necessary and advisable to attempt weaning from the tracheostomy tube at the earliest opportunity. However, while weaning protocols have proven successful in reducing ventilation time of critical care patients, there is little evidence of th... | ['Chi-Square Distribution', 'Clinical Nursing Research', 'Clinical Protocols', 'Critical Care', 'Evidence-Based Practice', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Care Planning', 'Pilot Projects', 'Prospective Studies', 'Research Design', 'Retrospective Studies', 'Time Factors', 'Tracheostomy', 'Ventilator ... | 19,366,410 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['H01.770.644.145.390.234', 'H02.478.395.234', 'N04.590.233.508.613.234'], ['E02.183', 'N05.715.360.330.125'], ['E02.760.190', 'N02.421.585.190'], ['H02.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of an anti-inflammatory 10,10a-dihydro-1H,5H-imidazo[1,5-b)isoquinoline-1,3(2H)-dione. | A new synthesis of imidazo[1,5-b]isoquinolines is reported. 2-[2-(Piperidino)ethyl]-10,10a-dihydro-1H,5H-imidazo[1,5-b]isoquinoline-1,3(2H)-dione hydrochloride was found to posses anti-inflammatory activity. | ['Anti-Inflammatory Agents', 'Isoquinolines', 'Methods'] | 641,821 | [['D27.505.954.158'], ['D03.633.100.531'], ['E05.581']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genomic structure of ornithine carbamoyltransferase gene from Canavalia lineata. | The nucleotide sequences of the complete ornithine carbamoyltransferase (OCT) gene containing 3,964 bp 3' region and 1,701 bp promoter region were determined from Canavalia lineata leaves. The exons range in size from 131 bp to 390 bp, while the introns range in size from 102 bp to the relatively large size of 1,465 bp... | ['Amino Acid Sequence', 'Arabidopsis', 'Base Sequence', 'Genes, Plant', 'Molecular Sequence Data', 'Ornithine Carbamoyltransferase', 'Promoter Regions, Genetic', 'Rosales', 'Sequence Analysis, DNA', 'Sequence Homology'] | 10,987,149 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['L01.453.245.667'], ['D08.811.913.555.275.600'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Treatment of peripheral arterial disease in diabetes: a consensus of the Italian Societies of Diabetes (SID, AMD), Radiology (SIRM) and Vascular Endovascular Surgery (SICVE). | Diabetic foot (DF) is a chronic and highly disabling complication of diabetes. The prevalence of peripheral arterial disease (PAD) is high in diabetic patients and, associated or not with peripheral neuropathy (PN), can be found in 50% of cases of DF. It is worth pointing out that the number of major amputations in dia... | ['Amputation', 'Angioplasty, Balloon', 'Cardiovascular Agents', 'Consensus', 'Diabetic Foot', 'Endovascular Procedures', 'Humans', 'Limb Salvage', 'Peripheral Arterial Disease', 'Predictive Value of Tests', 'Prevalence', 'Risk Factors', 'Treatment Outcome', 'Vascular Surgical Procedures'] | 24,486,336 | [['E04.555.080'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['D27.505.954.411'], ['F01.829.316.068', 'F02.463.785.373.433'], ['C14.907.320.191', 'C17.800.893.592.450.200', 'C19.246.099.500.191', 'C19.246.099.937.250'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prolonged recruitment efforts in health surveys: effects on response, costs, and potential bias. | BACKGROUND: In health surveys, considerable effort and expense are invested to achieve a high response proportion and thereby to reduce selection bias. We investigated the interrelation of recruitment efforts and expense with potential nonresponse bias based on data from a large health survey.METHODS: In a population-b... | ['Adult', 'Aged', 'Cost-Benefit Analysis', 'Data Collection', 'Female', 'Germany', 'Health Status', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Patient Selection', 'Selection Bias', 'Surveys and Questionnaires'] | 17,003,684 | [['M01.060.116'], ['M01.060.116.100'], ['N03.219.151.125'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['Z01.542.315'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Neuro-fuzzy models for hand movements induced by functional electrical stimulation in able-bodied and hemiplegic subjects. | Functional Electrical Stimulation (FES) may be effective as a therapeutic treatment for improving functional reaching and grasping. Upper-limb FES models for predicting joint torques/angles from stimulation parameters can be useful to support the iterative design and development of neuroprostheses. Most such models foc... | ['Adult', 'Aged', 'Biomechanical Phenomena', 'Case-Control Studies', 'Electric Stimulation Therapy', 'Female', 'Fuzzy Logic', 'Hand', 'Hemiplegia', 'Humans', 'Male', 'Middle Aged', 'Movement', 'Neural Networks, Computer'] | 27,346,491 | [['M01.060.116'], ['M01.060.116.100'], ['G01.154.090', 'G01.374.089'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['A01.378.800.667'], ['C10.597.622.295', 'C23.888.592.636.312'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Pre-existing autoimmune disease and the risk of immune-related adverse events among patients receiving checkpoint inhibitors for cancer. | INTRODUCTION: Patients with pre-existing autoimmune diseases have been excluded from clinical trials of immune checkpoint inhibitors (ICIs) for cancer. Real-world evidence is necessary to understand ICI safety in this population.METHODS: Patients treated with ICIs from 2011 to 2017 were identified using data from a lar... | ['Adrenal Cortex Hormones', 'Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Monoclonal', 'Autoimmune Diseases', 'B7-H1 Antigen', 'CTLA-4 Antigen', 'Female', 'Hospitalization', 'Humans', 'Immunotherapy', 'Insurance, Health', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasms', 'Programmed Cell Death 1 Recepto... | 30,877,325 | [['D06.472.040'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C20.111'], ['D12.776.465.625', 'D12.776.467.150.300', 'D12.776.543.095.300', 'D23.050.301.285.400', 'D23.529.168.300'], ['D12.776.465.782', 'D... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Accuracy and pitfalls of multidetector-row computed tomography in detecting spinal dural arteriovenous fistulas. | OBJECT: The purpose of this study was to evaluate the accuracy of multidetector-row CT angiography (MDCTA) in demonstrating spinal dural arteriovenous fistulas (SDAVFs).METHODS: The authors studied 10 patients with SDAVFs, including 2 with spinal epidural AVFs, who underwent preoperative MR imaging, MDCTA, and digital ... | ['Aged', 'Angiography', 'Angiography, Digital Subtraction', 'Central Nervous System Vascular Malformations', 'Female', 'Follow-Up Studies', 'Humans', 'Lumbar Vertebrae', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Retrospective Studies', 'Spinal Cord', 'Thoracic Vertebrae', 'Tomography, X-Ray Computed'] | 20,192,621 | [['M01.060.116.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['C10.500.190', 'C14.240.850.875', 'C16.131.240.850.875', 'C16.131.666.190'], ['E05.318.372.500.750.249', 'N05.715.360.33... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cognitive sequelae in relationship to early indices of severity of brain damage after severe blunt head injury. | A group of 89 severely head injured patients was tested psychologically within two years of injury, and test performance was related to indices of brain damage. Duration of coma (Glasgow Coma Scale) bore little relationship to later cognitive outcome but duration of post-traumatic amnesia significantly predicted cognit... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Amnesia', 'Brain Injuries', 'Cognition', 'Coma', 'Functional Laterality', 'Humans', 'Intelligence', 'Language', 'Learning', 'Middle Aged', 'Skull Fractures', 'Time Factors'] | 7,205,296 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C10.597.606.525.100', 'C23.888.592.604.529.100', 'F01.700.625.100', 'F03.615.200'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['F02.463.188'], ['C10.597.606.358.800.200', 'C23.888.592.604.359.800.200'], ['... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
MiR-20a triggers metastasis of gallbladder carcinoma. | BACKGROUND & AIMS: The dysfunction of miRNAs has been demonstrated to participate in the development of various tumors. However, whether miRNAs are involved in metastasis and progression of gallbladder carcinoma (GBC) remains unknown.METHODS: A new designed gain-of-function miRNA screening technology was applied to fil... | ['Animals', 'Cell Line, Tumor', 'Disease Progression', 'Epithelial-Mesenchymal Transition', 'Female', 'Gallbladder Neoplasms', 'Heterografts', 'Humans', 'Liver Neoplasms, Experimental', 'Male', 'Mice', 'Mice, Nude', 'MicroRNAs', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Neoplasm Transplantation', ... | 23,665,284 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['C23.550.291.656'], ['G04.356.500'], ['C04.588.274.120.401', 'C06.130.320.401', 'C06.130.564.401', 'C06.301.120.401'], ['A01.941.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E0... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy. | Cyclic nucleotide-gated (CNG) channels are activated by binding of cyclic nucleotides. Although structural studies have identified the channel pore and selectivity filter, conformation changes associated with gating remain poorly understood. Here we combine single-molecule force spectroscopy (SMFS) with mutagenesis, bi... | ['Animals', 'Computational Biology', 'Cyclic Nucleotide-Gated Cation Channels', 'Electrophysiological Phenomena', 'Female', 'Gene Expression Regulation', 'Ion Channel Gating', 'Ovarian Follicle', 'Protein Conformation', 'Protein Structure, Tertiary', 'Spectrum Analysis', 'Xenopus laevis'] | 25,963,832 | [['B01.050'], ['H01.158.273.180', 'L01.313.124'], ['D12.776.157.530.400.337', 'D12.776.543.550.450.452', 'D12.776.543.585.400.452'], ['G07.265'], ['G05.308'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['G02.111.570.820.709'], ['G02.111.570.820.709.610'], ['E0... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of physician education on the rates of donation request and tissue donation. | Our objective was to evaluate physician response to an educational program to increase referral of potential organ or tissue donors in an emergency department (ED). This study was a nonrandomized, controlled, before-after intervention trial at a nonuniversity teaching hospital with 45,000 annual patient visits to the E... | ['Education, Medical, Continuing', 'Emergency Service, Hospital', 'Humans', 'Physician-Patient Relations', 'Tissue Donors'] | 7,701,584 | [['I02.358.212.350', 'I02.358.399.250'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650.675', 'N05.300.660.625'], ['M01.898']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Quality control of antibodies for assay development. | Antibodies are used as powerful tools in basic research, for example, in biomarker identification, and in various forms for diagnostics, for example, identification of allergies or autoimmune diseases. Due to their robustness and ease of handling, immunoassays are favourite methods for investigation of various biologic... | ['Antibodies', 'Antibody Specificity', 'Biomarkers', 'Biotechnology', 'Cross Reactions', 'Humans', 'Illicit Drugs', 'Immunoassay', 'Quality Control', 'Substance-Related Disorders'] | 26,873,787 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.100'], ['D23.101'], ['H01.158.550', 'J01.897.120'], ['G12.122.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['E05.478.566', 'E05.601.470'], ['J01.897.608'], ['C25.775', 'F03.900']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Development of a nurse-managed, school-based health center. | As the healthcare environment continues to change, nurses are developing models for interdisciplinary care in a variety of community settings. The high school is an ideal treatment setting for the delivery of health services to adolescents. This article describes the development of a nurse-managed, school-based health ... | ['Adolescent', 'Adolescent Health Services', 'Clinical Competence', 'Education, Nursing, Baccalaureate', 'Humans', 'Program Development', 'Program Evaluation', 'Quality Assurance, Health Care', 'School Health Services', 'School Nursing'] | 8,936,183 | [['M01.060.057'], ['N02.421.044'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.462.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.760'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N04.761.700', 'N05.700'], ['N02.421.726.809'], ['H02.478.676.824', 'N02.421.726.809.742']] | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
AT4 receptor structure-binding relationship: N-terminal-modified angiotensin IV analogues. | The effect of structural changes in the N-terminal amino acid of AIV, with respect to AT4 receptor binding, was examined by competition with [125I]AIV in bovine adrenal membranes. Analogues with modifications of the first residue alpha-amino group possessed lower affinities than the primary amine-containing parent comp... | ['Adrenal Glands', 'Amino Acid Sequence', 'Angiotensin II', 'Angiotensin Receptor Antagonists', 'Animals', 'Binding, Competitive', 'Cattle', 'Cell Membrane', 'Kinetics', 'Molecular Sequence Data', 'Receptors, Angiotensin', 'Structure-Activity Relationship'] | 7,700,843 | [['A06.300.071'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D27.505.519.162'], ['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['B01.050.150.900.649.313... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Modulation of platelet-activating-factor-induced calcium influx and intracellular calcium release in platelets by phorbol esters. | The mechanisms by which platelet-activating factor (PAF) and thrombin increase intracellular calcium were examined. Platelets were loaded with the calcium-sensitive fluorescent probe Quin 2 and then were suspended in buffer containing 0.5 mM-Mn2+ in order to quantify simultaneously calcium release from intracellular st... | ['Blood Platelets', 'Calcium', 'Cations, Divalent', 'Diglycerides', 'Epoprostenol', 'Humans', 'Intracellular Fluid', 'Platelet Activating Factor', 'Spectrometry, Fluorescence', 'Tetradecanoylphorbol Acetate', 'Thrombin'] | 3,322,269 | [['A11.118.188', 'A15.145.229.188'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300.333'], ['D10.351.303'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.429', 'A11.284.835.450', 'A12.207.515'], ['D02.033.100.291.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential alpha-smooth muscle actin expression in a gastric epithelioid leiomyosarcoma in a 14 year old girl. | Leiomyosarcoma in childhood is very rare. This report describes the immunohistochemical study of a gastric epithelioid leiomyosarcoma in a 14 year old girl. Microscopically, the tumor showed two distinct histological patterns within the same tumor: small epithelioid cells forming a lobular pattern and spindle-shaped ce... | ['Actins', 'Adolescent', 'Female', 'Humans', 'Leiomyosarcoma', 'Muscle, Smooth', 'Stomach Neoplasms'] | 8,203,266 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['M01.060.057'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.455', 'C04.557.450.795.455'], ['A02.633.570', 'A10.690.467'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reaction mechanisms of Trp120-->Phe and wild-type glucoamylases from Aspergillus niger. Interactions with maltooligodextrins and acarbose. | Interactions of wild-type and Trp120-->Phe glucoamylase with maltooligodextrin (Gx) substrates and the tight-binding inhibitor acarbose (A) were investigated here using stopped-flow fluorescence spectroscopy and steady-state kinetic measurements. All wild-type and Trp120-->Phe glucoamylase reactions followed the three-... | ['Acarbose', 'Aspergillus niger', 'Carbohydrate Sequence', 'Dextrins', 'Glucan 1,4-alpha-Glucosidase', 'Kinetics', 'Ligands', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Phenylalanine', 'Spectrometry, Fluorescence', 'Structure-Activity Relationship', 'Trisaccharides', 'Tryptophan'] | 8,373,772 | [['D09.698.629.802.100'], ['B01.300.381.081.450'], ['G02.111.570.160', 'L01.453.245.667.160'], ['D05.750.078.562.855.375', 'D09.301.915.400', 'D09.698.365.855.400'], ['D08.811.277.450.420.375'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['D12.125.072.050.685', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Space-time wiring specificity supports direction selectivity in the retina. | How does the mammalian retina detect motion? This classic problem in visual neuroscience has remained unsolved for 50 years. In search of clues, here we reconstruct Off-type starburst amacrine cells (SACs) and bipolar cells (BCs) in serial electron microscopic images with help from EyeWire, an online community of 'citi... | ['Amacrine Cells', 'Animals', 'Artificial Intelligence', 'Brain Mapping', 'Crowdsourcing', 'Dendrites', 'Mice', 'Models, Neurological', 'Motion', 'Neural Pathways', 'Presynaptic Terminals', 'Retina', 'Retinal Bipolar Cells', 'Spatio-Temporal Analysis'] | 24,805,243 | [['A08.675.358.050', 'A08.675.650.850.500', 'A09.371.729.831.500', 'A11.671.358.050', 'A11.671.650.850.500'], ['B01.050'], ['G17.035.250', 'L01.224.050.375'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['L01.399.250.179'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['B01.050.150.... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Cytochrome P450 2D6 (CYP2D6) inhibitory constituents of Catharanthus roseus. | The MeOH-soluble fraction of the water extract of Catharanthus roseus from Indonesia, having shown potent inhibitory activity on the metabolism mediated by CYP2D6, was subjected to activity-guided isolation to yield two triterpenes, ursolic acid (1) and oleanolic acid (2), and three alkaloids, vindoline (3), ajmalicine... | ['Catharanthus', 'Cytochrome P-450 CYP2D6', 'Cytochrome P-450 CYP2D6 Inhibitors', 'Enzyme Inhibitors', 'Plant Components, Aerial', 'Plant Extracts'] | 15,930,738 | [['B01.650.940.800.575.912.250.456.500.260'], ['D08.244.453.005.600', 'D08.244.453.491.372', 'D08.811.682.690.708.170.010.600', 'D08.811.682.690.708.170.450.368', 'D12.776.422.220.453.010.600', 'D12.776.422.220.453.491.368'], ['D27.505.389.500.368', 'D27.505.519.389.335.368'], ['D27.505.519.389'], ['A18.024'], ['D20.21... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of increased intracardiac and arterial pressure on plasma vasopressin in humans. | The effects of loading cardiopulmonary and sinoaortic baroreceptors on plasma arginine vasopressin (AVP) levels were examined in 18 healthy young adults after a mild water restriction. Cardiopulmonary receptors were acutely loaded by volume expansion which increased central venous pressure (CVP) from 4.7 +/- 1.9 to 7.3... | ['Adult', 'Arginine Vasopressin', 'Blood Pressure', 'Cardiovascular System', 'Central Venous Pressure', 'Hemodynamics', 'Humans', 'Male', 'Posture', 'Sodium Chloride', 'Time Factors'] | 6,720,976 | [['M01.060.116'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07'], ['G09.330.380.076.732.336'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.695'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The study of fine and coarse particles, and metallic elements for the daytime and night-time in a suburban area of central Taiwan, Taichung. | Daily average concentrations of fine and coarse particulates, and TSP samples have been measured simultaneously at daytime and night-time periods by using Universal and PS-1 sampler in a suburban area of central Taiwan from June to August 1998. The samples were analyzed by atomic absorption spectrometry to determine th... | ['Air Pollutants', 'Darkness', 'Metals', 'Particle Size', 'Suburban Health', 'Taiwan'] | 10,834,362 | [['D27.888.284.101'], ['G01.590.540.233'], ['D01.552'], ['G02.712'], ['N01.400.548.813'], ['Z01.252.474.872', 'Z01.639.850']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Primitive neuroectodermal tumor (PNET) in the differential diagnosis of malignant kidney tumors. | Primitive neuroectodermal tumors (PNETs) of the kidney, a rare neoplastic disease of high malignancy with a tendency towards early metastasis, affect young adults (26-30 years) irrespective of the gender. Differential diagnosis from other renal tumors is very important for an effective therapy. Herein, we report on a 2... | ['Adult', 'Base Sequence', 'DNA, Neoplasm', 'Diagnosis, Differential', 'Humans', 'Immunohistochemistry', 'Kidney Neoplasms', 'Male', 'Microscopy, Electron', 'Neuroectodermal Tumors, Primitive', 'Ploidies'] | 12,390,000 | [['M01.060.116'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.425'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Time course of changes in ocular aberrations after instillation of carteolol long-acting solution and timolol gel-forming solution. | PURPOSE: To investigate the influence of 2% carteolol long-acting solution (long-acting carteolol) and 0.5% timolol gel-forming solution (timolol gel) on ocular wavefront aberrations.METHODS: Ocular aberrations were assessed in the right eye of 24 healthy volunteers at baseline and at 2, 5, 10, and 15 min after instill... | ['Adrenergic beta-Antagonists', 'Adult', 'Carteolol', 'Eye', 'Female', 'Gels', 'Humans', 'Male', 'Ophthalmic Solutions', 'Timolol'] | 21,314,439 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['D02.033.100.624.698.207', 'D02.033.755.624.698.207', 'D02.092.063.624.698.207', 'D03.633.100.810.835.188'], ['A01.456.505.420', 'A09.371'], ['D20.280.320', 'D26.255.165.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.776.7... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Opioid prescribing practices in a pediatric burn tertiary care facility: Is it time to change? | Opioids are the mainstay therapy in burned adults. Little data in the pediatric burn population exists that elucidates opioid prescribing practices. The primary purpose of this report is to quantify opioid and non-opioid analgesic use in pediatric burn patients admitted to a tertiary referral burn center. A retrospecti... | ['Acetaminophen', 'Administration, Intravenous', 'Administration, Oral', 'Adolescent', 'Ambulatory Care', 'Analgesics, Non-Narcotic', 'Analgesics, Opioid', 'Anesthesia, Conduction', 'Burn Units', 'Burns', 'Child', 'Child, Preschool', 'Codeine', 'Drug Combinations', 'Female', 'Fentanyl', 'Hospitalization', 'Humans', 'Hy... | 31,862,279 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['E02.319.267.082'], ['E02.319.267.100'], ['M01.060.057'], ['E02.760.106', 'N02.421.585.106'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Correlation between mannose-binding lectin gene codon 54 polymorphism and susceptibility of Kawasaki disease]. | OBJECTIVE: Human mannose-binding lectin (MBL) is a C-type serum lectin synthesized by the liver as an acute-phase protein. MBL can bind to glycoproteins terminated with mannose and N-acetylglucosamine present in the cell walls on a variety of microorganisms. Therefore, MBL appears to play an important role in the immun... | ['Child', 'Child, Preschool', 'Codon', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Infant', 'Male', 'Mannose-Binding Lectin', 'Mucocutaneous Lymph Node Syndrome', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Polymorphism, Restriction Fragment Length'] | 15,144,709 | [['M01.060.406'], ['M01.060.406.448'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D12.776.503.280.249.500', 'D12.776.503.311.500'], ['C14.907.940.560', 'C15.604.560', 'C17.800.862.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An introduction to contingent (closed-loop) brain electrical stimulation for seizure blockage, to ultra-short-term clinical trials, and to multidimensional statistical analysis of therapeutic efficacy. | Automated seizure blockage is a top research priority of the American Epilepsy Society. This delivery modality (referred to herein as contingent or closed loop) requires for implementation a seizure detection algorithm for control of delivery of therapy via a suitable device. The authors address the many potential adva... | ['Anticonvulsants', 'Clinical Trials as Topic', 'Electric Stimulation Therapy', 'Electrodes, Implanted', 'Electroencephalography', 'Epilepsy', 'Evoked Potentials', 'Humans', 'Signal Processing, Computer-Assisted', 'Treatment Outcome'] | 11,779,966 | [['D27.505.954.427.080'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Synthesis of 6-aryloxy- and 6-arylalkoxy-2-chloropurines and their interactions with purine nucleoside phosphorylase from Escherichia coli. | The phase transfer method was applied to perform the nucleophilic substitution of 2,6-dichloropurines by modified arylalkyl alcohol or phenols. Since under these conditions only the 6-halogen is exchanged, this method gives 2-chloro-6-aryloxy- and 2-chloro-6-arylalkoxy-purines. 2-Chloro-6-benzylthiopurine was synthesiz... | ['Enzyme Inhibitors', 'Escherichia coli', 'Molecular Structure', 'Purine-Nucleoside Phosphorylase', 'Purines', 'Stereoisomerism', 'Structure-Activity Relationship'] | 10,685,497 | [['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.570', 'G02.466'], ['D08.811.913.400.725.800'], ['D03.633.100.759'], ['G02.607.445.682'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Primary intracranial extraosseous Ewing's sarcoma. | INTRODUCTION: Common sites of occurrence of extraosseous Ewing's sarcoma include the soft tissues and bones of the lower extremity, 12 paravertebral, and retroperitoneal regions. Primary intracranial Ewing's sarcoma/pPNET is usually intraparenchymal located 13 when supratentorially, and an extraaxial epidural tumor rad... | ['Diagnosis, Differential', 'Dura Mater', 'Humans', 'Male', 'Meningeal Neoplasms', 'Meningioma', 'Sarcoma, Ewing', 'Soft Tissue Neoplasms', 'Young Adult'] | 30,353,305 | [['E01.171'], ['A08.186.566.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.557.580.520', 'C04.557.645.520', 'C04.588.614.250.580.500', 'C10.551.240.500.500'], ['C04.557.450.565.575.650.800', 'C04.557.450.795.620.800'], ['C04.588.839'], ['M01.060.116.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
microRNA-370 Promotes Cell Growth by Targeting WNK2 in Breast Cancer. | Aberrant expression of microRNA-370 (miR-370) has been found in many types of human cancers. In non-small cell lung cancer, miR-370 is a tumor suppressor with decreased expression. In prostate cancer, it is an oncogene with overexpression. Although upregulation of miR-370 was correlated with poor prognosis of breast ca... | ["3' Untranslated Regions", 'Animals', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cell Proliferation', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Mice, Nude', 'MicroRNAs', 'Protein-Serine-Threonine Kinases'] | 31,009,242 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Management of accessory hepatic ducts in choledochal cysts. | This report describes the surgical management of 2 children with fusiform choledochal cysts who had accessory hepatic ducts (AHD) identified during excisional surgery for fusiform choledochal cysts (CC). Two children presenting with a triad of recurrent jaundice, fever, and abdominal pain were investigated and found to... | ['Child, Preschool', 'Cholangiopancreatography, Endoscopic Retrograde', 'Choledochal Cyst', 'Female', 'Hepatic Duct, Common', 'Humans', 'Male'] | 11,431,790 | [['M01.060.406.448'], ['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['C04.182.198', 'C06.130.120.127', 'C06.198.184', 'C16.131.314.184'], ['A03.159.183.079.600'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors. | The obesity epidemic in industrialized countries is associated with increases in cardiovascular disease (CVD) and certain types of cancer. In animal models, caloric restriction (CR) suppresses these diseases as well as chemical-induced tissue damage. These beneficial effects of CR overlap with those altered by agonists... | ['Animals', 'Caloric Restriction', 'Cardiovascular Diseases', 'Cell Division', 'DNA-Binding Proteins', 'Female', 'Homeostasis', 'Lipid Metabolism', 'Liver', 'Liver X Receptors', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Orphan Nuclear Receptors', 'PPAR alpha', 'Peroxisome Proliferator-Activated Receptor Gamma Coactivator ... | 15,302,862 | [['B01.050'], ['E02.642.249.200', 'G07.203.650.240.340.150'], ['C14'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.776.260'], ['G07.410'], ['G03.458'], ['A03.620'], ['D12.776.260.531', 'D12.776.826.194'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Incidence of thyroid diseases in primary hyperparathyroidism]. | The incidence of thyroid diseases was evaluated in patients with primary hyperparathyroidism subjected to parathyroidectomy. Eleven patients (26.8%) were affected in this way: 2 with carcinoma, 5 with nodular goitre, and 4 with adenoma. The possible reasons for associations of this kind are discussed, and it is suggest... | ['Adenoma', 'Clinical Trials as Topic', 'Female', 'Goiter, Nodular', 'Humans', 'Hyperparathyroidism', 'Male', 'Thyroid Diseases', 'Thyroid Neoplasms'] | 379,703 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chondrolysis of the hip joint in a patient receiving long-term hemodialysis: histologic and biochemical evaluation. | We describe a patient undergoing long-term hemodialysis, in whom severe chondrolysis of the hip joint developed. The chondrolysis evolved in the absence of synovial inflammation and articular chondrocalcinosis. Biochemical studies of articular cartilage retained at surgery revealed deposition of exclusively small prote... | ['Cartilage Diseases', 'Cartilage, Articular', 'Female', 'Glycosaminoglycans', 'Hip Joint', 'Humans', 'Middle Aged', 'Proteoglycans', 'Radiography', 'Renal Dialysis', 'Sulfates', 'Synovial Membrane'] | 2,818,660 | [['C05.182', 'C17.300.182'], ['A02.165.407.150', 'A02.835.583.192'], ['D09.698.373'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D09.698.735', 'D12.776.395.650'], ['E01.370.350.700'], ['E02.870.300', 'E02.912.800'], ['D01.248.497.158.845', 'D01.875.800.800.850'], ['A02.... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reliability and validity of the scale for the assessment and rating of ataxia: a study in 64 ataxia patients. | The objective of this study was to test the reliability and validity of the Scale for the Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal dominant spinocerebellar ataxia (SCA). To this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independe... | ['Adolescent', 'Adult', 'Ataxia', 'Female', 'Health Status Indicators', 'Humans', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Severity of Illness Index'] | 17,516,493 | [['M01.060.057'], ['M01.060.116'], ['C10.597.350.090', 'C23.888.592.350.090'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.318.370... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
An initial characterization of human heart beta-adrenoceptors and their mediation of the positive inotropic effects of catecholamines. | The positive inotropic effects of catecholamines were studied on samples of ventricular myocardium taken from patients undergoing open heart surgery. The adenylyl cyclase and binding of 3H-(-)-bupranolol were examined in membrane particles prepared from similarly obtained samples. The equilibrium dissociation constant ... | ['Adenylyl Cyclases', 'Animals', 'Bupranolol', 'Catecholamines', 'Cats', 'Dose-Response Relationship, Drug', 'Humans', 'In Vitro Techniques', 'Myocardial Contraction', 'Myocardium', 'Receptors, Adrenergic', 'Receptors, Adrenergic, beta', 'Species Specificity', 'Stimulation, Chemical'] | 6,287,309 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['D02.033.100.624.698.146', 'D02.033.755.624.698.146', 'D02.092.063.624.698.146'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation. | Very little is known about the role of histone H3 phosphorylation in malignant transformation and cancer development. Here, we examine the function of H3 phosphorylation in cell transformation in vivo. Introduction of small interfering RNA-H3 into JB6 cells resulted in decreased epidermal growth factor (EGF)-induced ce... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Transformation, Neoplastic', 'Epidermal Growth Factor', 'Epithelial Cells', 'Gene Expression Regulation', 'Genes, fos', 'Genes, jun', 'Histones', 'Mice', 'Molecular Sequence Data', 'Phosphorylation', 'Promoter Regions, Genetic', 'Proto-Oncogene Proteins c-fos', ... | 15,994,958 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['A11.436'], ['G05.308'], ['G05.360.340.024.340.375.500.791.330'], ['G05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of two multifocal intraocular lens designs that differ only in near add. | PURPOSE: To evaluate monocular functional outcomes after the implantation of the AcrySof ReSTOR SN6AD2 intraocular lens (IOL) (+2.5 diopters [D] near add) (Alcon Laboratories, Inc., Fort Worth, TX) and the AcrySof ReSTOR SN6AD1 IOL (+3.0 D near add) (Alcon Laboratories, Inc.).METHODS: This prospective, comparative, non... | ['Capsulorhexis', 'Female', 'Humans', 'Lens Implantation, Intraocular', 'Lenses, Intraocular', 'Male', 'Middle Aged', 'Phacoemulsification', 'Prospective Studies', 'Prosthesis Design', 'Pseudophakia', 'Refraction, Ocular', 'Visual Acuity'] | 25,375,848 | [['E04.540.825.249.352'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.540.825.600'], ['E07.632.500.460', 'E07.695.460'], ['M01.060.116.630'], ['E04.540.825.249.704', 'E04.943.875'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.320.550', 'E07.695.680'], ['C2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast. | The v-erbA oncogene is a retrovirus-transduced and altered copy of a cellular gene for a thyroid hormone receptor. In animal cells, the v-erbA protein fails to respond to hormone and acts as a dominant negative allele, inhibiting gene activation normally conferred by the wild-type thyroid hormone receptor. We report he... | ['Animals', 'Base Sequence', 'Cell Line', 'Cell Transformation, Neoplastic', 'Chromosome Deletion', 'Cloning, Molecular', 'Gene Expression Regulation, Fungal', 'Genetic Vectors', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Oligonucleotide Probes', 'Oncogene Proteins v-erbA', 'Oncogenes', 'Plasmids', 'Prom... | 1,979,758 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['E05.393.220'], ['G05.308.330'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Qualitative angiographic and quantitative myocardial perfusion assessment using fluorescent cardiac imaging during graded coronary artery bypass stenosis. | Intraoperative graft assessment in coronary artery bypass (CAB) grafting is important to avoid early graft failure. This study aimed to evaluate the accuracy of fluorescent cardiac imaging (FCI) for intraoperative qualitative angiographic and quantitative myocardial perfusion assessment during graded CAB stenosis compa... | ['Animals', 'Blood Flow Velocity', 'Constriction, Pathologic', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Circulation', 'Disease Models, Animal', 'Female', 'Fluorescent Dyes', 'Graft Occlusion, Vascular', 'Indocyanine Green', 'Luminescent Measurements', 'Male', 'Myocardial Perfusion Imaging', 'Optical ... | 28,712,068 | [['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['C23.300.287'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['G09.330.100.324'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.72... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pilot study on the efficacy of an ondansetron- versus palonosetron-containing antiemetic regimen prior to highly emetogenic chemotherapy. | PURPOSE: Nausea and vomiting are among the most feared complications of chemotherapy reported by patients. The objective of this study was to establish the overall complete response (CR; no emesis or use of rescue medication 0-120 h after chemotherapy) with either ondansetron- or palonosetron-containing antiemetic regi... | ['Adult', 'Aged', 'Antiemetics', 'Antineoplastic Combined Chemotherapy Protocols', 'Aprepitant', 'Breast Neoplasms', 'Cyclophosphamide', 'Dexamethasone', 'Doxorubicin', 'Female', 'Humans', 'Isoquinolines', 'Middle Aged', 'Morpholines', 'Nausea', 'Ondansetron', 'Palonosetron', 'Pilot Projects', 'Prospective Studies', 'Q... | 23,748,485 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.533.640.125'], ['C04.588.180', 'C17.800.090.500'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D04.210.500.745.432.769.344'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extraction, purification and antioxidant activity of novel polysaccharides from Dendrobium officinale | Two novel polysaccharides DOP1-DES and DOP2-DES with molecular weight of 297,911 Da and 30,400 Da were extracted by using DESs from Dendrobium officinale for the first time, and purified with macroporous resin AB-8, Sephadex G75 and Sephadex G200 chromatography. Besides, the effect of extraction temperature, molar rati... | ['Antioxidants', 'Dendrobium', 'Glucose', 'Magnetic Resonance Spectroscopy', 'Mannose', 'Monosaccharides', 'Plant Extracts', 'Polysaccharides', 'Solvents', 'Spectroscopy, Fourier Transform Infrared'] | 29,726,707 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.650.940.800.575.912.250.618.100.640.222'], ['D09.947.875.359.448'], ['E05.196.867.519'], ['D09.947.875.359.588'], ['D09.947.875'], ['D20.215.784.500', 'D26.667'], ['D09.698'], ['D27.720.844'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Haloperidol Reduces the Activity of Complement and Induces the Anti-Inflammatory Transformation of Peritoneal Macrophages in Rats. | It is known that psychotropic substances affect the immune system. Unfortunately, chronic antipsychotic administration causes side toxicological effects, associated with oxidative stress. The mechanisms of these effects are still unclear. We investigated the impact of sub-chronic administration of haloperidol (Hal) on ... | ['Animals', 'Complement Activation', 'Glutathione', 'Glutathione Reductase', 'Glutathione Transferase', 'Haloperidol', 'Hemostasis', 'Immunity, Innate', 'Inflammation', 'Leukocyte Elastase', 'Macrophages, Peritoneal', 'Male', 'Nitric Oxide', 'Nitric Oxide Synthase Type II', 'Oxidation-Reduction', 'Phagocytosis', 'Rats'... | 31,280,407 | [['B01.050'], ['G12.274'], ['D12.644.456.448'], ['D08.811.682.667.092'], ['D08.811.913.225.500'], ['D02.522.352.506'], ['G09.188.390'], ['G12.450.564'], ['C23.550.470'], ['D08.811.277.656.300.760.560.500', 'D08.811.277.656.959.350.560.500'], ['A11.329.372.630', 'A11.627.482.630', 'A11.733.397.630', 'A15.382.670.522.630... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
T1-T2-T3 glottic tumors: fifteen years experience with CO2 laser. | This research aims at reporting the results of endoscopic treatment of glottic carcinomas by CO2 laser. The cases cited concern 516 patients with glottic T1-T2-T3 carcinomas. The patients have been divided into 5 groups: a) T1a: 194 patients with monolateral carcinoma involving the true vocal cord who underwent simple ... | ['Carcinoma, Squamous Cell', 'Endoscopy', 'Glottis', 'Humans', 'Laryngeal Neoplasms', 'Laryngectomy', 'Laryngoscopy', 'Laser Therapy', 'Survival Rate', 'Vocal Cords'] | 9,197,509 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.370.388.250', 'E04.502.250'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['E04.580.369'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Numerical compression schemes for proteomics mass spectrometry data. | The open XML format mzML, used for representation of MS data, is pivotal for the development of platform-independent MS analysis software. Although conversion from vendor formats to mzML must take place on a platform on which the vendor libraries are available (i.e. Windows), once mzML files have been generated, they c... | ['Algorithms', 'Databases, Protein', 'Mass Spectrometry', 'Numerical Analysis, Computer-Assisted', 'Proteomics', 'Software'] | 24,677,029 | [['G17.035', 'L01.224.050'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['E05.196.566'], ['L01.224.680.700'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Changes to the Disordered Phase and Apatite Crystallite Morphology during Mineralization by an Acidic Mineral Binding Peptide from Osteonectin. | Noncollagenous proteins regulate the formation of the mineral constituent in hard tissue. The mineral formed contains apatite crystals coated by a functional disordered calcium phosphate phase. Although the crystalline phase of bone mineral was extensively investigated, little is known about the disordered layer's comp... | ['Apatites', 'Humans', 'Osteonectin', 'Peptides'] | 26,207,448 | [['D01.029.260.700.675.374.075.025', 'D01.146.360.050', 'D01.578.122', 'D01.695.625.675.650.075.025'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.125.715', 'D12.776.395.600'], ['D12.644']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insoluble fibres, satiety and food intake in cats fed kibble diets. | Fibre is generally considered to dilute food energy, alter intestinal transit time and promote satiety; however, in cats, conflicting results have been found. In this study, two insoluble fibres were evaluated in four feline diets: control (no added fibre); diet with 10% sugar cane fibre; diet with 20% sugar cane fibre... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Cats', 'Diet', 'Dietary Fiber', 'Female', 'Male', 'Satiety Response'] | 27,080,580 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G07.203.650.240'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['F02.830.749.658']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Clinical evaluation of extracellular ADMA concentrations in human blood and adipose tissue. | Circulating asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthesis, has been proposed as a biomarker for clinical outcome. Dimethylarginine dimethylaminohydrolase (DDAH) is the main enzyme responsible for ADMA metabolism and elimination. Adipose tissue ADMA concentrations and DDAH activ... | ['Adipose Tissue', 'Adult', 'Amidohydrolases', 'Arginine', 'Case-Control Studies', 'Diabetes Mellitus', 'Extracellular Fluid', 'Female', 'Humans', 'Male', 'Microdialysis', 'Middle Aged', 'Obesity, Morbid', 'Weight Loss'] | 24,445,256 | [['A10.165.114'], ['M01.060.116'], ['D08.811.277.087'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C18.452.394.750', 'C19.246'], ['A11.284.295.260', 'A12.207.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fluorodeoxyglucose positron emission tomography in pulmonary carcinoid tumors. | AIM: The role of fluorodeoxyglucose positron emission tomography (FDG-PET) as an additional investigation to computer tomography for pulmonary carcinoid tumors remains controversial. The aim of this study was to assess the role of FDG-PET for the diagnosis and staging of pulmonary carcinoid tumors.METHODS: We performed... | ['Adolescent', 'Adult', 'Aged', 'Carcinoid Tumor', 'Female', 'Fluorodeoxyglucose F18', 'Follow-Up Studies', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Ki-67 Antigen', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Positron-Emission Tomography', 'Preoperative Period', 'Prognosis', 'Retrospective... | 26,416,036 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['D09.254.229.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Two cases of giant serpentine aneurysm. | Giant serpentine aneurysm (GSA) is an entity defined on radiological and pathological grounds as a giant, partially thrombosed aneurysm containing tortuous vascular channels. We have had the opportunity to study two patients with GSAs, which has allowed for a complete comparative anatomical and radiological study. This... | ['Adult', 'Cerebral Arteries', 'Cerebrovascular Circulation', 'Female', 'Humans', 'Hypertrophy', 'Intracranial Aneurysm', 'Intracranial Embolism and Thrombosis', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 2,362,659 | [['M01.060.116'], ['A07.015.114.228'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['C10.228.140.300.525', 'C14.907.253.566', 'C14.907.355.590.213'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.35... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effects of antagonists of exciting amino acids on the neuro-destructive effect of quinolinic acid in vitro in comparison with their anticonvulsive action in situ]. | A comparative study of the influence of kynurenic acid (KYNA), L-kynurenine (KYN) and ethylimidazole-4-5-dicarboxylic acid (IEM-1442) on neuro-destructive effect of quinolinic acid (QUIN) in hippocampal cell cultures of mouse embryos and on convulsive action of QUIN after its injection into the brain ventricles of adul... | ['Animals', 'Anticonvulsants', 'Cells, Cultured', 'Dicarboxylic Acids', 'Hippocampus', 'Imidazoles', 'Kynurenic Acid', 'Kynurenine', 'Mice', 'Mice, Inbred C57BL', 'Neurons', 'Pyridines', 'Quinolinic Acid', 'Quinolinic Acids'] | 2,529,920 | [['B01.050'], ['D27.505.954.427.080'], ['A11.251'], ['D02.241.081.337'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D03.383.129.308'], ['D03.066.942.505', 'D03.633.100.810.350.400'], ['D12.125.608'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mayer's hemalum-methyl salicylate: a stain-clearing technique for observations within whole ovules. | Nondissected ovaries of tuber-bearing Solanum sp. were stained with Mayer's hemalum, a positive stain for chromatin and nucleoli, and then optically cleared with methyl salicylate, a clearing agent. Clarity, resolution and contrast within the ovules dissected from ovaries were comparable to those of sectioned, paraffin... | ['Alum Compounds', 'Aluminum', 'Benzopyrans', 'Hematoxylin', 'Plant Cells', 'Salicylates', 'Staining and Labeling'] | 6,207,641 | [['D01.056.025', 'D01.875.800.800.850.025'], ['D01.268.557.050', 'D01.552.547.050'], ['D03.383.663.283', 'D03.633.100.150'], ['D03.383.663.283.600', 'D03.633.100.150.600'], ['A11.750'], ['D02.241.223.100.300.595', 'D02.241.511.390.595', 'D02.455.426.559.389.127.281.595', 'D02.455.426.559.389.657.410.595'], ['E01.370.22... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fundic gland polyps are not induced by proton pump inhibitor therapy. | It is still unclear whether proton pump inhibitors (PPIs) could cause fundic gland polyps (FGPs) in patients without Helicobacter pylori infection. The frequency of FGPs in patients during PPI therapy has not been compared, however with a control group of patients who did not have H. pylori infection and were not under... | ['Enzyme Inhibitors', 'Female', 'Gastric Fundus', 'Gastritis', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Middle Aged', 'Omeprazole', 'Polyps', 'Proton Pump Inhibitors', 'Retrospective Studies'] | 11,710,689 | [['D27.505.519.389'], ['A03.556.875.875.419'], ['C06.405.205.697', 'C06.405.748.398'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.886.640.074.500', 'D03.383.725.024.500', 'D03.633.100.103.034.500'], ['C23.300.8... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Selective inhibition of cGMP-inhibitable cAMP phosphodiesterase decreases pulmonary vasoreactivity. | Guanosine 3',5'-cyclic monophosphate (cGMP) and adenosine 3',5'-cyclic monophosphate (cAMP) are mediators of smooth muscle relaxation. In this study, selective inhibitors of phosphodiesterase (PDE) isozymes were used to assess the role of cyclic nucleotide hydrolysis in angiotensin II (ANG II) and hypoxic pulmonary vas... | ["3',5'-Cyclic-AMP Phosphodiesterases", 'Angiotensin II', 'Animals', 'Blood', 'Blood Pressure', 'Cyclic GMP', 'Hypoxia', 'In Vitro Techniques', 'Male', 'Perfusion', 'Phosphodiesterase Inhibitors', 'Pulmonary Circulation', 'Rats', 'Vasoconstriction'] | 1,652,213 | [['D08.811.277.352.640.150', 'D12.644.360.008', 'D12.776.476.008'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['A12.207.152', 'A15.145'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.633.100.759.646.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
IRAK-M regulates the inhibition of TLR-mediated macrophage immune response during late in vitro Leishmania donovani infection. | Intramacrophage protozoan parasite Leishmania donovani, causative agent of visceral leishmaniasis, escapes Toll-like receptor (TLR) dependent early host immune response by inducing the deubiquitinating enzyme A20, which is sustained up to 6 h postinfection only. Therefore, Leishmania must apply other means to deactivat... | ['Animals', 'Cell Line', 'Interleukin-1 Receptor-Associated Kinases', 'Leishmania donovani', 'Leishmaniasis, Visceral', 'Macrophages', 'Mice', 'Mice, Inbred BALB C', 'NF-kappa B', 'Phosphorylation', 'Toll-Like Receptors', 'Transforming Growth Factor beta'] | 26,140,693 | [['B01.050'], ['A11.251.210'], ['D08.811.913.696.620.682.700.526', 'D12.644.360.370', 'D12.776.476.384'], ['B01.268.475.868.488.230'], ['C01.610.752.300.500.510', 'C01.920.813.510'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[On the indications for and morbidity of segmental resection of the mandible for squamous cell carcinoma in the lower oral cavity]. | BACKGROUND: Segmental resection of the mandibula in oral cancer surgery leads to both functional and aesthetic problems. The decision to preserve or resect the mandible depends on the vicinity of the lesion to the bone. Consequently, based on the rules of safety margins to all planes that are recommended for soft tissu... | ['Aged', 'Bone Plates', 'Carcinoma, Squamous Cell', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mandible', 'Mandibular Prosthesis Implantation', 'Middle Aged', 'Mouth Floor', 'Mouth Neoplasms', 'Mouth Rehabilitation', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Postoperative Compli... | 15,834,743 | [['M01.060.116.100'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632', 'A1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Compound stimulus presentation and the norepinephrine reuptake inhibitor atomoxetine enhance long-term extinction of cocaine-seeking behavior. | Drug abstinence is frequently compromised when addicted individuals are re-exposed to environmental stimuli previously associated with drug use. Research with human addicts and in animal models has demonstrated that extinction learning (non-reinforced cue-exposure) can reduce the capacity of such stimuli to induce rela... | ['Adrenergic Uptake Inhibitors', 'Animals', 'Atomoxetine Hydrochloride', 'Cocaine-Related Disorders', 'Disease Models, Animal', 'Drug-Seeking Behavior', 'Extinction, Psychological', 'Male', 'Norepinephrine', 'Propylamines', 'Rats', 'Rats, Sprague-Dawley'] | 22,089,320 | [['D27.505.519.562.437.050', 'D27.505.519.625.050.601', 'D27.505.519.625.600.050', 'D27.505.696.577.050.601', 'D27.505.696.577.600.050'], ['B01.050'], ['D02.092.831.085'], ['C25.775.300', 'F03.900.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['F01.145.342'], ['F02.463.425.770.232'], ['D02.033.100.291.502', 'D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correction of Stahl ear deformity using a suture technique. | Correction of partial ear deformities can be a challenging task for the plastic surgeon. There are no standard techniques for correcting many of these deformities, and several different techniques are described in literature. Stahl ear is one such anomaly, characterized by an accessory third crus in the ear cartilage, ... | ['Adult', 'Ear Cartilage', 'Ear, External', 'Humans', 'Male', 'Suture Techniques'] | 20,856,059 | [['M01.060.116'], ['A02.165.257.250', 'A09.246.272.549'], ['A09.246.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.987.775']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis. | Vertebrate bone morphogenetic protein 1 (BMP-1) and Drosophila Tolloid (TLD) are prototypes of a family of metalloproteases with important roles in various developmental events. BMP-1 affects morphogenesis, at least partly, via biosynthetic processing of fibrillar collagens, while TLD affects dorsal-ventral patterning ... | ['Amino Acid Sequence', 'Animals', 'Body Patterning', 'Bone Morphogenetic Protein 1', 'Bone Morphogenetic Proteins', 'Bone and Bones', 'Cloning, Molecular', 'Drosophila Proteins', 'Enzyme Activation', 'Glycoproteins', 'Humans', 'Insect Proteins', 'Intercellular Signaling Peptides and Proteins', 'Metalloendopeptidases',... | 10,479,448 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G07.345.500.100'], ['D08.811.277.656.300.480.525.700.049', 'D08.811.277.656.675.374.525.700.900.500', 'D12.644.276.848.049', 'D12.644.276.948.500', 'D12.644.276.954.200.100', 'D12.776.467.836.049', 'D12.776.467.942.200.100', 'D12.776.467.948.500', 'D23.529.942... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transvaginal sonography and human chorionic gonadotrophin measurements in suspected ectopic pregnancy: a detailed analysis of a diagnostic approach. | In this prospective study among 208 high-risk patients with suspected ectopic pregnancy, the diagnostic value of transvaginal sonography and serum human chorionic gonadotrophin (HCG) measurements were analysed in detail. The absence of an intra-uterine gestational sac obviously was the most constant sonographic finding... | ['Adnexa Uteri', 'Chorionic Gonadotropin', 'False Negative Reactions', 'Female', 'Humans', 'Pregnancy', 'Pregnancy, Ectopic', 'Prospective Studies', 'Risk Factors', 'Ultrasonography', 'Uterus'] | 8,408,533 | [['A05.360.319.114'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['E01.354.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C13.703.733'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.740... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Laparoscopic splenectomy for blunt trauma: a safe operation following embolization. | BACKGROUND: Embolization of the injured spleen from blunt trauma reduces the risk of continued or delayed hemorrhage in patients being treated with nonoperative management (NOM). Splenectomy is required in some patients following embolization due to continued bleeding or infarction with abscess formation. Laparoscopic ... | ['Cohort Studies', 'Embolization, Therapeutic', 'Humans', 'Laparoscopy', 'Postoperative Hemorrhage', 'Retreatment', 'Retrospective Studies', 'Spleen', 'Splenectomy', 'Treatment Outcome', 'Wounds, Nonpenetrating'] | 18,461,390 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C23.550.414.941', 'C23.550.767.850'], ['E02.887'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.71... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparing alternative cholera vaccination strategies in Maela refugee camp: using a transmission model in public health practice. | BACKGROUND: Cholera is a major public health concern in displaced-person camps, which often contend with overcrowding and scarcity of resources. Maela, the largest and longest-standing refugee camp in Thailand, located along the Thai-Burmese border, experienced four cholera outbreaks between 2005 and 2010. In 2013, a c... | ['Cholera', 'Cholera Vaccines', 'Disease Outbreaks', 'Humans', 'Models, Theoretical', 'Public Health', 'Refugee Camps', 'Sanitation', 'Thailand', 'Vaccination'] | 31,864,298 | [['C01.150.252.400.959.347'], ['D20.215.894.135.225'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['J03.340.825'], ['H02.229.782', 'N06.850.780.200.800', 'N06.850.860'], ['Z01.252.145.841'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.8... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Acarbose reduces the risk of pre-lunch hypoglycemia in elderly people with diabetes eating rice porridge for breakfast. | To decrease the risk of postprandial hyperglycemia and late hypoglycemia in elderly people with diabetes who eat rice porridge for breakfast, we administered 50mg acarbose to 30 elderly people with type 2 diabetes. The results demonstrated that acarbose could prevent the fluctuations in post-breakfast blood glucose lev... | ['Acarbose', 'Aged', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Hypoglycemia', 'Hypoglycemic Agents', 'Male', 'Middle Aged', 'Oryza', 'Postprandial Period'] | 20,619,914 | [['D09.698.629.802.100'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['D27.505.696.422'], ['M01.060.116.630'], ['B01.650.940.800.575.912.250.822.616'], ['G10.261.700']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pseudohomogeneous kinetic study on a two-liquid-phase fermentation process. | The fermentation process for producing undecane dicarboxylic acid from tridecane, which includes gas-oil-water-cell four phases (two-liquid-phase), was studied. The metabolic characters of the cell growth phase and the production phase of the process were analyzed. It was proposed that cell growth can be identified by ... | ['Alkanes', 'Candida', 'Dicarboxylic Acids', 'Fermentation', 'Hydrogen-Ion Concentration', 'Kinetics', 'Models, Biological', 'Paraffin', 'Petroleum', 'Time Factors'] | 7,780,024 | [['D02.455.326.146'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['D02.241.081.337'], ['G02.111.158.249', 'G03.191.249'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['E05.599.395'], ['D02.455.612'], ['D20.345.630', 'N06.230.132.258.630'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Models for genetic evaluations of claw health traits in Spanish dairy cattle. | Genetic parameters of 7 claw health traits from Spanish dairy cattle were estimated and the predictive ability of linear and ordinal threshold models were compared and assessed. This study included data on interdigital and digital dermatitis (DE), sole ulcer (SU), white line disease (WL), interdigital hyperplasia (IH),... | ['Animals', 'Cattle', 'Cattle Diseases', 'Digital Dermatitis', 'Female', 'Genetic Variation', 'Hoof and Claw', 'Linear Models', 'Phenotype', 'Spain'] | 26,387,016 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C01.150.252.819.180', 'C01.800.720.180', 'C17.800.838.765.180', 'C22.214'], ['G05.365'], ['A13.491'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', '... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Correlation between Seralyzer reflectance photometer theophylline assay and an Emit assay. | Recently a method for theophylline assay on the Ames Seralyzer was introduced. We compared the interday variability of this method to the established interday variability of an enzyme multiplied immunoassay (Emit) technique used in the service laboratory of a hospital. Control sera and calibrator prepared to known conc... | ['Adolescent', 'Child', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Photometry', 'Theophylline'] | 3,307,546 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E05.196.712'], ['D03.132.960.751', 'D03.633.100.759.758.824.751']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The lambeosaurine dinosaur Magnapaulia laticaudus from the late cretaceous of Baja California, Northwestern Mexico. | The taxonomy, osteology, phylogenetic position, and historical biogeography of the lambeosaurine hadrosaurid Magnapaulia laticaudus (new combination) are revised. The diagnosis of this species is amended on the basis on two autapomorphies (i.e., longest haemal arches of proximal caudal vertebrae being at least four tim... | ['Animals', 'Dinosaurs', 'Fossils', 'Mexico'] | 22,719,869 | [['B01.050'], ['B01.050.150.900.833.150'], ['I01.076.368.584.311'], ['Z01.107.567.589']] | ['Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Uptake of ingested bovine lactoferrin and its accumulation in adult mouse tissues. | Lactoferrin is a glycoprotein with antimicrobial and immunoregulatory properties, which is found in milk, other external secretions, and in the secondary granules of neutrophils. The present study examined the time course of uptake and the pattern of tissue accumulation of bovine lactoferrin (bLf) following intragastri... | ['Administration, Oral', 'Animals', 'Brain', 'Cattle', 'Female', 'Gallbladder', 'Gastrointestinal Tract', 'Immunoglobulin A', 'Immunoglobulin G', 'Intestinal Absorption', 'Kidney', 'Lactoferrin', 'Liver', 'Mice', 'Mice, Inbred BALB C', 'Spleen', 'Tissue Distribution'] | 17,673,154 | [['E02.319.267.100'], ['B01.050'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['A03.159.439'], ['A03.556'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.54... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension. | BACKGROUND AND PURPOSE: Apelin is an endogenous vasodilatory and inotropic peptide that is down-regulated in human pulmonary arterial hypertension, although the density of the apelin receptor is not significantly attenuated. We hypothesised that a G protein-biased apelin analogue MM07, which is more stable than the end... | ['Animals', 'Apelin Receptors', 'Disease Models, Animal', 'Male', 'Monocrotaline', 'Pulmonary Arterial Hypertension', 'Rats', 'Rats, Sprague-Dawley'] | 30,710,493 | [['B01.050'], ['D12.776.543.750.695.006'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D03.132.716.500', 'D03.633.100.772.500'], ['C08.381.423.847'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of bone-conducted music on swimming performance. | Music has been shown to be a useful adjunct for many forms of exercise and has been observed to improve athletic performance in some settings. Nonetheless, because of the limited availability of practical applications of sound conduction in water, there are few studies of the effects of music on swimming athletes. The ... | ['Adolescent', 'Adult', 'Athletes', 'Athletic Performance', 'Bone Conduction', 'Cross-Over Studies', 'Female', 'Humans', 'MP3-Player', 'Male', 'Middle Aged', 'Music', 'Swimming', 'Young Adult'] | 22,371,093 | [['M01.060.057'], ['M01.060.116'], ['M01.072'], ['I03.450.642.845.054'], ['F02.830.816.263.500', 'G07.888.500.500', 'G11.561.790.263.398'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.820.090.615'], ['M01.060.116.630'], ['K01.602'], ['G11... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Seed banking of terrestrial orchids: evaluation of seed quality in Anacamptis following 4-year dry storage. | Good-quality dry seeds of some orchids have the potential to survive for decades under conventional seed bank conditions, but further research is needed to fill existing gaps in knowledge regarding seed behaviour under long-term dry storage. The objectives of this study were to evaluate germination ability on two asymb... | ['Desiccation', 'Germination', 'Orchidaceae', 'Seed Bank', 'Seeds', 'Temperature'] | 30,430,713 | [['E05.196.335', 'G02.176'], ['G07.345.625.249', 'G15.357'], ['B01.650.940.800.575.912.250.618.100.640'], ['N02.278.065.650'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Transmission electron microscopy as an aid in the management of infertile men]. | Light microscopic evaluation of the semen of infertile men with sperm motility and morphological problems and Kartagener's syndrome does not always provide sufficient evidence for the cause of infertility. Transmission electron microscopy (TEM) was performed on selected primary and secondary male infertility patients t... | ['Cilia', 'Humans', 'Infertility, Male', 'Male', 'Microscopy, Electron', 'Sperm Count', 'Sperm Motility', 'Sperm Tail', 'Spermatozoa'] | 4,012,488 | [['A11.284.180.165'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.225.500.195.870', 'E01.370.225.992.624', 'E05.200.500.195.870', 'E05.200.992.624', 'E05.242.195.870', 'G04.140.870'], ['E01.370.225.992.812', 'E05.200.992.812', 'G04.198.750'], [... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prevention and diagnosis of encapsulated endometrium after endometrial ablation]. | Endometrial ablation for dysfunctional uterine bleeding has become more common in Denmark in recent years. New symptoms and diseases may arise due to morphological changes in the uterus after the operation. Despite thoroughness during surgery, residual endometrial tissue can be trapped in pockets during the healing pro... | ['Adult', 'Endometrium', 'Female', 'Humans', 'Postoperative Complications', 'Uterine Hemorrhage', 'Wound Healing'] | 9,540,420 | [['M01.060.116'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['C13.351.500.852.691', 'C23.550.414.993'], ['G16.762.891']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment with levamisole of recurrent herpes genitalis. | A double-blind study was carried out to investigate the possibility of therapeutic effect of levamisole on recurrent progenital herpes. One hundred and nine patients, including 53 females, entered the study, but only 75 completed. Levamisole, 50 mg three times daily for 3 days, was started at the first sign of recurren... | ['Adult', 'Clinical Trials as Topic', 'Double-Blind Method', 'Drug Evaluation', 'Female', 'Genital Diseases, Female', 'Genital Diseases, Male', 'Herpesviridae Infections', 'Humans', 'Levamisole', 'Male', 'Recurrence'] | 208,462 | [['M01.060.116'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.290.625', 'E05.337.425'], ['C13.351.500'], ['C12.294'], ['C01.925.256.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Developing research priorities for palliative care of people with intellectual disabilities in Europe: a consultation process using nominal group technique. | BACKGROUND: Empirical knowledge around palliative care provision and needs of people with intellectual disabilities is extremely limited, as is the availability of research resources, including expertise and funding. This paper describes a consultation process that sought to develop an agenda for research priorities fo... | ['Consensus', 'Europe', 'Health Services Research', 'Humans', 'Intellectual Disability', 'Palliative Care', 'Research'] | 27,009,550 | [['F01.829.316.068', 'F02.463.785.373.433'], ['Z01.542'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['E02.760.666', 'N02.421.585.666'], ['H01.770.644']] | ['Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
The impact of perceived childhood victimization and patriarchal gender ideology on intimate partner violence (IPV) victimization among Korean immigrant women in the USA. | Childhood victimization experiences are common among intimate partner violence (IPV) victims. This study examines the link between childhood physical and sexual victimization experiences and adulthood IPV among Korean immigrant women in the USA. As Korean immigrants often use physical punishment to discipline their chi... | ['Adult', 'Adult Survivors of Child Abuse', 'Asian Americans', 'Case-Control Studies', 'Child', 'Child Abuse', 'Emigrants and Immigrants', 'Family Characteristics', 'Female', 'Humans', 'Intimate Partner Violence', 'Middle Aged', 'Republic of Korea', 'Surveys and Questionnaires', 'United States'] | 28,599,125 | [['M01.060.116'], ['M01.135.500', 'M01.860.300.500'], ['M01.686.508.200.100', 'M01.686.754.225'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.189'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Identification of bovine-specific DNA in feedstuffs. | Considering the menace of transmission of bovine spongiform encephalopathy, feed components intended for cattle nutrition must be checked for the presence of bovine-derived materials. We have been using a method based on polymerase chain reaction for the identification of bovine-specific mitochondrial DNA sequences for... | ['Animal Feed', 'Animals', 'Biological Products', 'Cattle', 'Chickens', 'DNA Primers', 'DNA, Mitochondrial', 'Encephalopathy, Bovine Spongiform', 'Fish Products', 'Food Contamination', 'Horses', 'Meat', 'Minerals', 'Polymerase Chain Reaction', 'Rabbits', 'Sensitivity and Specificity', 'Sequence Analysis, DNA', 'Sheep',... | 11,198,432 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['D20.215'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.283.225'], ['C01.207.800.260', 'C10.228.228.800.260', 'C10.574.843.300... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Strategies proposed by Healthy Kids, Healthy Communities partnerships to prevent childhood obesity. | INTRODUCTION: Healthy Kids, Healthy Communities (HKHC) is an initiative of the Robert Wood Johnson Foundation to prevent obesity among high-risk children by changing local policies, systems, and environments. In 2009, 105 community partnerships applied for funding from HKHC. Later that year, the Centers for Disease Con... | ['Centers for Disease Control and Prevention, U.S.', 'Child', 'Community Health Services', 'Health Policy', 'Health Promotion', 'Humans', 'Life Style', 'Obesity', 'Practice Guidelines as Topic', 'Prevalence', 'Public Health', 'Residence Characteristics', 'Retrospective Studies', 'United States'] | 22,172,178 | [['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['M01.060.406'], ['N02.421.143'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['C18.654.726.500', 'C23.888.144... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographica... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. | Type I interferons (IFN-I) are important cytokines linking innate and adaptive immunity. Plasmacytoid dendritic cells make high levels of IFN-I in response to viral infection and are thought to be the major source of the cytokines in vivo. Here, we show that conventional non-plasmacytoid dendritic cells taken from mice... | ['3T3 Cells', 'Animals', 'CpG Islands', 'Dendritic Cells', 'Interferon Type I', 'Interferon-alpha', 'Lymphocytic Choriomeningitis', 'Lymphocytic choriomeningitis virus', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'RNA, Double-Stranded', 'Receptors, Cell Surface', 'Signal Transduction... | 12,819,664 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['D12.644.276.374.440.890.250', 'D12.776.4... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of cardiovascular calcifications on the detrimental effect of continued smoking on cardiovascular risk in male lung cancer screening participants. | BACKGROUND: Current smokers have an increased cardiovascular disease (CVD) risk compared to ex-smokers due to reversible as well as irreversible effects of smoking. We investigated if current smokers remain to have an increased CVD risk compared to ex-smokers in subjects with a long and intense smoking history. We in a... | ['Aged', 'Aorta, Thoracic', 'Cardiovascular Diseases', 'Coronary Artery Disease', 'Coronary Vessels', 'Early Detection of Cancer', 'Follow-Up Studies', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Radiography', 'Risk Factors', 'Smoking', 'Vascular Calcification'] | 23,840,486 | [['M01.060.116.100'], ['A07.015.114.056.372'], ['C14'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.269', 'A07.015.908.194'], ['E01.390.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genetic specificity of face recognition. | Specific cognitive abilities in diverse domains are typically found to be highly heritable and substantially correlated with general cognitive ability (g), both phenotypically and genetically. Recent twin studies have found the ability to memorize and recognize faces to be an exception, being similarly heritable but ph... | ['Adolescent', 'Adult', 'Cognition', 'Face', 'Female', 'Humans', 'Male', 'Recognition, Psychology', 'Twins, Dizygotic', 'Twins, Monozygotic', 'Visual Perception'] | 26,417,086 | [['M01.060.057'], ['M01.060.116'], ['F02.463.188'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.706'], ['M01.438.873.920'], ['M01.438.873.940'], ['F02.463.593.932']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhanced mechanical properties of thermosensitive chitosan hydrogel by silk fibers for cartilage tissue engineering. | Articular cartilage has limited repair capability following traumatic injuries and current methods of treatment remain inefficient. Reconstructing cartilage provides a new way for cartilage repair and natural polymers are often used as scaffold because of their biocompatibility and biofunctionality. In this study, we a... | ['Animals', 'Biocompatible Materials', 'Cartilage, Articular', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Chitosan', 'Chondrocytes', 'Collagen Type II', 'Fibroins', 'Glycerophosphates', 'Glycosaminoglycans', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Hydrogels', 'Nanofibers', 'Rabbits', 'Regenerat... | 24,094,188 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A02.165.407.150', 'A02.835.583.192'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['D05.750.078.139.500', 'D09.698.211.500'], ['A11.329.171'], ['D05.750.078.280.300.200', 'D12.776.860.300.250.300.200'], ['D05.750.078.875.500', 'D12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
The chicken c-erbA alpha-product induces expression of thyroid hormone-responsive genes in 3,5,3'-triiodothyronine receptor-deficient rat hepatoma cells. | To determine the capacity of the chicken c-erbA (cTR-alpha) gene product in regulating expression of known thyroid hormone-responsive genes, both the cTR-alpha and the viral v-erbA genes were expressed in FAO cells, a rat hepatoma cell line defective for functional thyroid hormone receptors. Upon nuclear expression of ... | ['Animals', 'Base Sequence', 'Chickens', 'Cycloheximide', 'Gene Expression', 'Genes', 'Genomic Library', 'Liver Neoplasms, Experimental', 'Malate Dehydrogenase', 'Molecular Sequence Data', 'Phosphoenolpyruvate Carboxykinase (GTP)', 'Promoter Regions, Genetic', 'Proto-Oncogene Proteins', 'Rats', 'Receptors, Thyroid Horm... | 2,158,623 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D03.383.621.808.240'], ['G05.297'], ['G05.360.340.024.340'], ['G05.360.325.425', 'G05.360.340.425'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Muscle chamber with strain gauge adapted for isotonic/isometric recording. | Simple devices are described that can facilitate student experiments on mechanical and electrical aspects of muscle contraction, for example, of isolated preparations such as frog gastrocnemius and sartorius muscles and gut. The system includes a general-purpose preparation bath that was previously described for electr... | ['Animals', 'Electric Stimulation', 'Electrophysiology', 'Equipment Design', 'Humans', 'Isometric Contraction', 'Isotonic Contraction', 'Leg', 'Muscles'] | 8,712,253 | [['B01.050'], ['E05.723.402'], ['H01.158.344.528', 'H01.158.782.236'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['G11.427.494.493'], ['A01.378.610.500'], ['A02.633', 'A10.690']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. | The role of monocytes/macrophages in the pathogenesis of ischemia-reperfusion injury (IRI) is unknown. We sought to determine whether activation of macrophage adenosine 2A (A(2A)) receptors (A(2A)Rs) mediates tissue protection. We subjected C57Bl/6 mice infused with clodronate [dichloromethylene bisphosphonate (Cl(2)MB... | ['Acute Kidney Injury', 'Adenosine A2 Receptor Agonists', 'Animals', 'Antimetabolites', 'Cell Line', 'Clodronic Acid', 'Cyclohexanecarboxylic Acids', 'Cytokines', 'Humans', 'Kidney', 'Liposomes', 'Macrophages', 'Mice', 'Mice, Inbred C57BL', 'Purines', 'RNA, Messenger', 'Receptor, Adenosine A2A', 'Reperfusion Injury', '... | 15,561,971 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['D27.505.519.625.725.200.100.200', 'D27.505.696.577.725.200.100.200'], ['B01.050'], ['D27.505.519.186', 'D27.888.569.042'], ['A11.251.210'], ['D02.705.429.500.200'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of hydroxypropyl-beta-cyclodextrin on the central stimulant activity of (-)-ephedrine and an oxazolidine prodrug in rats. | 1. Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) increases the stability of the oxazolidine prodrug toward hydrolysis. 2. The binding constant (Kb) and rate constant (Kc) for the hydrolysis of the prodrug-HP-beta-CD complex were calculated from the kinetic data. 3. Ion-spray mass spectra confirmed prodrug-HP-beta-CD com... | ['2-Hydroxypropyl-beta-cyclodextrin', 'Adrenergic Agents', 'Animals', 'Cyclodextrins', 'Dose-Response Relationship, Drug', 'Ephedrine', 'Male', 'Mass Spectrometry', 'Oxazoles', 'Prodrugs', 'Rats', 'Rats, Sprague-Dawley', 'beta-Cyclodextrins'] | 9,559,325 | [['D04.345.103.333.500', 'D09.301.915.400.375.333.500', 'D09.698.365.855.400.375.333.500'], ['D27.505.519.625.050', 'D27.505.696.577.050'], ['B01.050'], ['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.100.624.302', 'D02.033.755.624.302', 'D02.092.063.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mock-up experiment at Birmingham University for BNCT project of Osaka University--Neutron flux measurement with gold foil. | Mock-up experiment for development of accelerator based neutron source for Osaka University BNCT project was carried out at Birmingham University, UK. In this paper, spatial distribution of neutron flux intensity was evaluated by foil activation method. Validity of the design code system was confirmed by comparing meas... | ['Boron Neutron Capture Therapy', 'Gold', 'Neutrons'] | 26,275,798 | [['E02.815.722.500.100'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['G01.249.660.250']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Isovolumic and auxovolumic constants of cardiac relaxation in evaluating its inotropism]. | The left ventricular pressure curve was registered in experiments on isolated guinea pig heart performing external work. An analysis of initial diastolic portion of the curve in logarithmic scale has revealed for the first time that the time course of the pressure fall is accelerated during transition from isovolumic t... | ['Animals', 'Blood Pressure', 'Calcium', 'Cardiac Output', 'Cardiac Volume', 'Egtazic Acid', 'Guinea Pigs', 'Heart Rate', 'In Vitro Techniques', 'Myocardial Contraction', 'Phenothiazines', 'Stimulation, Chemical', 'Ventricular Function'] | 3,085,691 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E01.370.370.380.150', 'G09.330.380.124'], ['G09.330.380.249'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['B01.050.150.900.649.313.992.550'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E05.481... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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