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CT colonography versus optical colonoscopy for screening asymptomatic patients for colorectal cancer a patient, intervention, comparison, outcome (PICO) analysis.
RATIONALE AND OBJECTIVES: The American College of Radiology has recently endorsed the use of computed tomographic colonography (CTC) for colon cancer screening. With advances in technology and postprocessing software, the quality of computed tomographic colonographic studies has improved, and new techniques are being d...
['Colonography, Computed Tomographic', 'Colonoscopy', 'Colorectal Neoplasms', 'Humans', 'Incidence', 'Mass Screening', 'Outcome Assessment, Health Care', 'Prognosis', 'Reproducibility of Results', 'Sensitivity and Specificity']
19,345,897
[['E01.370.350.350.810.180', 'E01.370.350.600.350.700.810.180', 'E01.370.350.700.700.810.180', 'E01.370.350.700.810.810.180', 'E01.370.372.230'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]']
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Unbiased Screens Show CD8+
Developing effective strategies to prevent or treat coronavirus disease 2019 (COVID-19) requires understanding the natural immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We used an unbiased, genome-wide screening technology to determine the precise peptide sequences in SARS-CoV-2 that ...
['Adult', 'Aged', 'Betacoronavirus', 'CD8-Positive T-Lymphocytes', 'COVID-19', 'Convalescence', 'Coronavirus', 'Coronavirus Infections', 'Coronavirus Nucleocapsid Proteins', 'Epitope Mapping', 'Epitopes, T-Lymphocyte', 'Female', 'Humans', 'Immunodominant Epitopes', 'Immunologic Memory', 'Male', 'Middle Aged', 'Nucleoca...
33,128,877
[['M01.060.116'], ['M01.060.116.100'], ['B04.820.578.500.540.150.113'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500']...
['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
1
1
1
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[Reproducibility of densitometric examinations of the tibial shaft].
The aim of this paper is to evaluate the reproducibility of tibial shaft densitometry in own method under development. It will be expressed as percentage value of coefficient of variability (%CV). Bone mineral content (BMC) and bone mineral density (BMD) were measured with a dual energy X-ray densitometer Lunar DPX; th...
['Absorptiometry, Photon', 'Adult', 'Bone Density', 'Humans', 'Male', 'Reference Values', 'Reproducibility of Results', 'Tibia']
9,026,419
[['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116'], ['G11.427.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.978.810'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['A02.835.232.043.650.883']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]']
1
1
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Oxy133, a novel osteogenic agent, promotes bone regeneration in an intramembranous bone-healing model.
Current reconstructive techniques for complex craniofacial osseous defects are challenging and are associated with significant morbidity. Oxysterols are naturally occurring cholesterol oxidation products with osteogenic potential. In this study, we investigated the effects of a novel semi-synthetic oxysterol, Oxy133, o...
['Animals', 'Bone Marrow Cells', 'Bone Marrow Transplantation', 'Bone Regeneration', 'Calcification, Physiologic', 'Cell Differentiation', 'Male', 'Osteogenesis', 'Rabbits', 'Sterols', 'Stromal Cells']
26,073,881
[['B01.050'], ['A11.148', 'A15.378.316'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G11.427.213.140', 'G16.762.150.150'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['G04.152'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['B01.050.150.900.649.313....
['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]']
1
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Multiple arterial grafting confers survival advantage compared to percutaneous intervention with drug-eluting stents in multivessel coronary artery disease: A propensity score adjusted analysis.
BACKGROUND: The best revascularisation strategy for multivessel coronary artery disease (MVD) is still controversial. Percutaneous coronary intervention (PCI) utilising drug eluting stents (DES) has emerged as an acceptable alternative to conventional coronary artery bypass grafting (CABG) in the last decade. However, ...
['Aged', 'Aged, 80 and over', 'Angioplasty, Balloon, Coronary', 'Cause of Death', 'Cohort Studies', 'Confidence Intervals', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Databases, Factual', 'Drug-Eluting Stents', 'Female', 'Hospital Mortality', 'Humans', 'Male', 'Metals', 'Middle Aged',...
25,897,895
[['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]']
0
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KITLG is a novel target of miR-34c that is associated with the inhibition of growth and invasion in colorectal cancer cells.
MiR-34c is considered a potent tumour suppressor because of its negative regulation of multiple target mRNAs that are critically associated with tumorigenesis and metastasis. In the present study, we demonstrated a novel target of miR-34c, KITLG, which has been implicated in colorectal cancer (CRC). First, we found a s...
['Apoptosis', 'Blotting, Western', 'Cell Cycle', 'Cell Movement', 'Cell Proliferation', 'Colorectal Neoplasms', 'Fluorescent Antibody Technique', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MicroRNAs', 'RNA, Messenger', 'RNA, Small Interfering', 'Real-Time Polymerase Chain Reaction', 'Reverse Transcriptase Pol...
25,213,795
[['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.49...
['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]']
1
1
1
1
1
0
1
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Clinical study on prevention of HBV re-infection by entecavir after liver transplantation.
PURPOSE: This aims to evaluate the effects of lamivudine (LAM) and entecavir (ETV) in preventing hepatitis B virus (HBV) re-infection after liver transplantation (LT).METHODS: A retrospective matched case-control method was used in this study. From June 2005 to May 2007, the patients who received LAM (100 mg qd) or ETV...
['Adult', 'Aged', 'Antiviral Agents', 'Case-Control Studies', 'DNA, Viral', 'End Stage Liver Disease', 'Female', 'Guanine', 'Hepatitis B Antibodies', 'Hepatitis B Antigens', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Lamivudine', 'Liver Transplantation', 'Male', 'Middle Aged', 'Secondary Prevention']
21,981,656
[['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.388'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D13.444.308.568'], ['C06.552.308.500.177'], ['D03.633.100.759.758.399.454'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D12.776.377.715.54...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]']
0
1
1
1
1
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0
0
0
0
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1
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Subjective assessment of chewing function of obturator prosthesis wearers.
PURPOSE: Assessments of masticatory performance and occlusal force for wearers of obturator prostheses were performed as clinical objective assessments and reported in an earlier study. The purpose of the present study was to evaluate clinically the chewing function of obturator prosthesis wearers by self-evaluations a...
['Bite Force', 'Female', 'Humans', 'Male', 'Mastication', 'Middle Aged', 'Palatal Obturators', 'Statistics, Nonparametric', 'Surveys and Questionnaires']
17,319,362
[['E06.276.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.283.500', 'G10.261.330.500'], ['M01.060.116.630'], ['E06.780.346.850', 'E07.695.190.600'], ['E05.318.740.995', 'N05.715.360.750.760', 'N06.850.520.830.995'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]']
0
1
0
0
1
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1
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0
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1
1
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Functional domains of the InsA protein of IS2.
The InsA protein is a transcriptional regulator. It binds to the promoter region of insA and insAB'. To understand the molecular mechanism for the interaction between InsA and its binding sequence, the functional domains of InsA were identified. The glutaraldehyde cross-linking method and the two-hybrid expression syst...
['Base Sequence', 'Cloning, Molecular', 'Cross-Linking Reagents', 'DNA Transposable Elements', 'DNA, Bacterial', 'DNA-Binding Proteins', 'Dimerization', 'Escherichia coli', 'Escherichia coli Proteins', 'Genetic Vectors', 'Glutaral', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Repressor Proteins', 'Saccharo...
9,335,268
[['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D27.720.470.410.210'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D13.444.308.212'], ['D12.776.260'], ['G02.206', 'G03.230'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.1...
['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]']
0
1
0
1
1
0
1
0
0
0
1
0
0
0
Filter transient response to EEG waveforms.
The response of two types of linear filters to sinusoidal bursts was calculated to demonstrate how filters can distort EEG waveforms. Results show that the wider the filter bandwidth the less is the distortion, and for a given bandwidth, the higher the filter order the greater the distortion. The response of a linear p...
['Electroencephalography', 'Humans', 'Signal Processing, Computer-Assisted']
3,557,698
[['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.800']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]']
0
1
0
0
1
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The computed tomographic appearances in chronic berylliosis.
Computed tomography (CT) of the thorax was performed in eight patients with chronic berylliosis. The pulmonary CT features were variable and included pulmonary nodularity, and patterns consistent with upper lobe fibrosis or diffuse interstitial fibrosis. Mediastinal or hilar lymphadenopathy was shown in three cases. CT...
['Adult', 'Aged', 'Berylliosis', 'Chronic Disease', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed']
8,428,413
[['M01.060.116'], ['M01.060.116.100'], ['C08.381.483.581.225', 'C08.381.520.702.225', 'C24.800.225'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.8...
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
1
1
1
0
1
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1
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Somitic disruption of GNAS in chick embryos mimics progressive osseous heteroplasia.
Progressive osseous heteroplasia (POH) is a rare developmental disorder of heterotopic ossification (HO) caused by heterozygous inactivating germline mutations in the paternal allele of the GNAS gene. Interestingly, POH lesions have a bewildering mosaic distribution. Using clinical, radiographic, and photographic docum...
['Adolescent', 'Adult', 'Animals', 'Avian Proteins', 'Chick Embryo', 'Child', 'Child, Preschool', 'Disease Models, Animal', 'GTP-Binding Protein alpha Subunits, Gs', 'Humans', 'Loss of Heterozygosity', 'Mutation, Missense', 'Ossification, Heterotopic', 'Somites', 'Young Adult']
23,863,715
[['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D12.776.095'], ['A13.350.150', 'A16.331.200'], ['M01.060.406'], ['M01.060.406.448'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D08.811.277.040.330.300.200.100.400', 'D12.644.360.360.100.400', 'D12.776.157.325.332.100.400', 'D12.776.476.375.100.400', 'D12.776.543....
['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
1
1
1
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1
0
0
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Prevalence of hepatitis E virus antibodies, Israel, 2009-2010.
We investigated prevalence of hepatitis E virus in a sample of the population of Israel. The overall seroprevalence of antibodies to the virus was 10.6% (95% CI 8.4%-13.0%); age-adjusted prevalence was 7.6%. Seropositivity was associated with age, Arab ethnicity, low socioeconomic status, and birth in Africa, Asia, or ...
['Adolescent', 'Adult', 'Aged', 'Female', 'Genotype', 'Hepatitis Antibodies', 'Hepatitis E', 'Hepatitis E virus', 'History, 21st Century', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Israel', 'Male', 'Middle Aged', 'Odds Ratio', 'Prevalence', 'Seroepidemiologic Studies', 'Young Adult']
25,811,302
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G05.380'], ['D12.776.124.486.485.114.254.450', 'D12.776.124.790.651.114.254.450', 'D12.776.377.715.548.114.254.450'], ['C01.925.440.470', 'C01.925.782.455', 'C06.552.380.705.470'], ['B04.450.412', 'B04.820.578.407.400'], ['K01.400.504.984'], ['B01.050.150.900.64...
['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
1
1
1
0
1
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1
Inlay "butterfly" cartilage tympanoplasty.
OBJECTIVES: The aim of this study was to analyze the outcome of inlay "butterfly" cartilage tympanoplasty.METHODS: The files of 42 patients (24 were male, 18 were female) who underwent primary or revision inlay butterfly cartilage tympanoplasty in 2005 to 2011 at a tertiary medical center were reviewed. Patients were r...
['Adolescent', 'Adult', 'Aged', 'Audiometry', 'Ear Cartilage', 'Female', 'Follow-Up Studies', 'Hearing', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Treatment Outcome', 'Tympanic Membrane Perforation', 'Tympanoplasty', 'Young Adult']
22,975,316
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.382.375.060'], ['A02.165.257.250', 'A09.246.272.549'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]']
1
1
1
0
1
1
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Masc-induced dosage compensation in silkworm cultured cells.
The Masculinizer (Masc) gene encodes a CCCH-tandem zinc finger protein that controls both masculinization and dosage compensation in the silkworm Bombyx mori. We previously measured the masculinizing activity of the lepidopteran Masc proteins using B. mori ovary-derived cell line BmN-4. Here, we established an RNA-seq ...
['Animals', 'Bombyx', 'Cell Proliferation', 'Cells, Cultured', 'Cysteine', 'Dosage Compensation, Genetic', 'Insect Proteins']
31,294,930
[['B01.050'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G05.308.203.249'], ['D12.776.093.500']]
['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
[Diagnosis, Prognosis, Monitoring of Cardiac Complications of Arterial Hypertension. Hypertensive Heart Disease].
AIM: of the study was further investigation of diagnostics and management of cardiac complications of essential hypertension (EH).METHODS: Retrospective analysis of annual reports of cardiological departments for 10 year period was carried out. Internists (n=330) from 6 regions of Russia participated in the study. Anon...
['Adult', 'Aged', 'Echocardiography', 'Female', 'Heart Diseases', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Russia']
28,290,817
[['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.36...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]']
0
1
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Dietary Pattern Trajectories from 6 to 12 Months of Age in a Multi-Ethnic Asian Cohort.
UNLABELLED: Little is known about the dietary patterns of Asian infants in the first year of life, nor of their associations with maternal socio-demographic factors. Based on the Growing Up in Singapore towards healthy Outcomes (GUSTO) mother-offspring cohort, cross-sectional dietary patterns were derived by factor ana...
['Asian Continental Ancestry Group', 'China', 'Cohort Studies', 'Cross-Sectional Studies', 'Diet', 'Diet Records', 'Ethnic Groups', 'Fruit', 'Humans', 'Infant', 'Infant Formula', 'Infant Nutritional Physiological Phenomena', 'Linear Models', 'Milk, Human', 'Nutrition Assessment', 'Singapore', 'Socioeconomic Factors', '...
27,314,387
[['M01.686.508.200'], ['Z01.252.474.164'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['N04.452.859.360'], ['M01.686.754', 'N01.224.317'], ['A18.024.500', 'G07.203.300.562', 'J02.500.5...
['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
1
1
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Enteric descending and afferent neural signaling stimulated by giant migrating contractions: essential contributing factors to visceral pain.
We investigated whether strong compression of an intestinal segment by giant migrating contractions (GMCs) initiates pseudoaffective signals from the gut, similar to those initiated by its distension with a balloon. The experiments were performed on conscious dogs by using close intra-arterial infusions of test substan...
['Afferent Pathways', 'Animals', 'Atropine', 'Calcitonin Gene-Related Peptide', 'Colic', 'Dogs', 'Enteric Nervous System', 'Female', 'Gastrointestinal Motility', 'Heart Rate', 'Inflammatory Bowel Diseases', 'Intestine, Small', 'Irritable Bowel Syndrome', 'Male', 'Methacholine Chloride', 'Muscarinic Antagonists', 'Muscl...
16,990,445
[['A08.612.220'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['D12.644.400.097', 'D12.776.631.650.097'], ['C16.614.166'], ['B01.050.150.900.649.313.750.250.216.200'], ['A08.800.050.150'], ['G10.261.360'], ['E01.37...
['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
1
1
0
1
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Reversed needle pass clear-corneal or limbal incision suturing technique using the 3-throw (1-1-1) adjustable square knot.
A single radial suture is required for a corneal or limbal incision that does not seal despite stromal hydration. In the traditional technique for placing this suture, the needle enters from the corneal side of the limbal incision and exits toward the scleral side and the suture is usually tied with a 3-1-1 surgical kn...
['Cataract Extraction', 'Cornea', 'Humans', 'Limbus Corneae', 'Nylons', 'Suture Techniques', 'Sutures']
22,624,889
[['E04.540.825.249'], ['A09.371.060.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.217.659'], ['D05.750.716.392', 'D25.720.716.392', 'J01.637.051.720.716.392', 'J01.637.548'], ['E04.987.775'], ['E07.858.690.820']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]']
1
1
0
1
1
0
0
0
0
1
0
0
0
0
Polymorphisms in ABCG2, ABCC3 and CNT1 genes and their possible impact on chemotherapy outcome of lung cancer patients.
The prognosis of lung cancer patients treated with chemotherapy is poor, motivating the search for predictive factors. Single nucleotide polymorphisms (SNPs) in membrane transporter genes could influence the pharmacokinetics of cytostatic drugs and therefore affect treatment outcome. We examined 6 SNPs with known or su...
['ATP Binding Cassette Transporter, Subfamily G, Member 2', 'ATP-Binding Cassette Transporters', 'Antineoplastic Agents', 'Drug Resistance, Neoplasm', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Lung Neoplasms', 'Male', 'Membrane Transport Proteins', 'Middle Aged', 'Multidrug Resistance-Associated Proteins', 'Neoplas...
19,107,936
[['D12.776.157.530.100.228.500', 'D12.776.395.550.020.457.500', 'D12.776.543.550.192.457.500', 'D12.776.543.585.100.228.500'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.954.248'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]']
0
1
1
1
1
0
1
0
0
0
0
1
1
0
Reversal of functional changes in the brain associated with obstructive sleep apnoea following 6 months of CPAP.
Obstructive sleep apnoea (OSA) is associated with an increase in the number of bursts of muscle sympathetic nerve activity (MSNA), leading to neurogenic hypertension. Continuous positive airway pressure (CPAP) is the most effective and widely used treatment for preventing collapse of the upper airway in OSA. In additio...
['Adult', 'Aged', 'Brain', 'Brain Mapping', 'Cerebral Cortex', 'Continuous Positive Airway Pressure', 'Electroencephalography', 'Electromyography', 'Female', 'Functional Neuroimaging', 'Gyrus Cinguli', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Parahippocampal Gyrus', 'Parietal ...
26,082,888
[['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.405.255', 'E01.370.530.255'], ['E01.370.350.578.875', 'E01...
['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
New spatiotemporal approaches for fully refocused, multislice ultrafast 2D MRI.
PURPOSE: Single-scan multislice acquisition schemes play key roles in magnetic resonance imaging. Central among these "ultrafast" experiments stands echo-planar imaging, a technique that although of optimal sampling is challenged by T2* artifacts. Recent studies described alternatives based on spatiotemporal encoding (...
['Algorithms', 'Artifacts', 'Brain', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Information Storage and Retrieval', 'Magnetic Resonance Imaging', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spatio-Temporal Analysis']
23,468,061
[['G17.035', 'L01.224.050'], ['E05.047'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.313.500.750.280', 'L01.470'], ['E01.370.350.825.500'], ['E05.318.370.725', 'E05.337.851', 'N05....
['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]']
1
1
0
0
1
0
1
0
0
0
1
0
1
0
Aromatase expression in ovarian epithelial cancers.
Our study focused on aromatase cytochrome P450 (CYP19) expression in ovarian epithelial normal and cancer cells and tissues. Aromatase mRNA expression was analyzed by real-time PCR in ovarian epithelial cancer cell lines, in human ovarian surface epithelial (HOSE) cell primary cultures, and in ovarian tissue specimens ...
['Androstadienes', 'Aromatase', 'Aromatase Inhibitors', 'Cell Proliferation', 'Cysts', 'Epithelial Cells', 'Estrogen Receptor alpha', 'Female', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunohistochemistry', 'Lasers', 'Letrozole', 'Microdissection', 'Middle Aged', ...
15,748,828
[['D04.210.500.054.079.129'], ['D08.244.453.489.500', 'D08.244.453.915.099', 'D08.811.682.690.708.170.447.500', 'D08.811.682.690.708.170.915.099', 'D12.776.422.220.453.489.500', 'D12.776.422.220.453.915.099'], ['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['G04.161.750', 'G0...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]']
1
1
1
1
1
0
1
1
0
0
0
1
0
0
Reverse transcription-polymerase chain reaction detection of collagen transcripts in healing human wounds.
The aim of this study was to analyse the expression of COl1A1, COl1A2 and COl3A1 in 6 mm diameter punch biopsies obtained from human wounds. Total RNA was isolated from biopsies taken from Sacrococcygeal pilonidal sinus excision cavities at weekly intervals between surgery and clinical closure. cDNAs were generated fro...
['Biopsy', 'Collagen', 'DNA, Complementary', 'Humans', 'Pilonidal Sinus', 'Polymerase Chain Reaction', 'Procollagen', 'Transcription, Genetic', 'Wound Healing']
7,556,374
[['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C0...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
0
0
0
0
0
0
0
Adrenocorticoid hormones and the development and expression of mammalian monogamy.
Based on research with prairie voles, we hypothesize that the unusual patterns of reproduction and social behavior associated with mammalian monogamy may arise as a consequence of normal developmental exposure to high levels of glucocorticoids and/or other hormones of the HPA axis. Increased HPA activity could function...
['Adrenal Cortex Hormones', 'Animals', 'Arvicolinae', 'Corticosterone', 'Hypothalamo-Hypophyseal System', 'Mammals', 'Pituitary-Adrenal System', 'Rats', 'Sexual Behavior, Animal', 'Stress, Physiological']
8,597,447
[['D06.472.040'], ['B01.050'], ['B01.050.150.900.649.313.992.635.075'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357'], ['B01.050.150.900.649'], ['A06.300.691'], ['B01.050.150.900.649.313.992.635.505.700'], ['F...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]']
1
1
0
1
0
1
1
0
0
0
0
0
0
0
Computerized physician order entry of injectable antineoplastic drugs: an epidemiologic study of prescribing medication errors.
PURPOSE: In the context of CPOE of standardized antineoplastic drugs, the objectives of the present study were to determine the incidence of prescribing medication errors (PME) and to analyse PME related to antineoplastic treatment in university teaching hospitals.METHODS: All consecutive prescribing medication orders ...
['Adult', 'Aged', 'Antineoplastic Agents', 'Female', 'Humans', 'Injections, Intravenous', 'Male', 'Medical Order Entry Systems', 'Medication Errors', 'Middle Aged']
20,829,102
[['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['L01.313.500.750.300.695.600', 'N04.452.442.452.452.500', 'N04.452.515.360.500', 'N04.452.859.564.650.500'], ['E02.319.529', 'N02.421.450.500'], ['M01.060.116.630...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]']
0
1
0
1
1
0
0
0
0
0
1
1
1
0
Efficiency of energy conversion by aerobic glucose metabolism in Aphancapsa 6714.
Efficiency of adenosine triphosphate (ATP) formation from glucose oxidation in Aphanocapsa 6714 was estimated by quantitative measurement of phosphorylated intermediary metabolites and glycogen (polyglucose) formed from (14)C-glucose. P/2e ratios based on oxygen uptake ranged from 2.62 to 3.08, whereas those based on (...
['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Aerobiosis', 'Anaerobiosis', 'Autoradiography', 'Carbon Dioxide', 'Carbon Isotopes', 'Chromatography, Paper', 'Cyanobacteria', 'Glucose', 'Glucosephosphates', 'Glycogen', 'Oxidation-Reduction', 'Oxidative Phosphorylation', 'Oxygen Consumption', 'Phosphates', 'Phospho...
4,199,518
[['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.017', 'G03.049'], ['G02.111.062', 'G03.078'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D01.200.200', 'D01.362.150', 'D01.650.550.20...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
Interlaminar approach for epiduroscopy in patients with failed back surgery syndrome.
BACKGROUND: Epiduroscopy is a relatively new diagnostic and therapeutic technique used in patients with chronic low back pain with or without radiculopathy. We present our experience with a new interlaminar approach in patients with failed back surgery syndrome (FBSS).METHODS: Patients with severe symptoms of FBSS who ...
['Adult', 'Chronic Disease', 'Endoscopy', 'Epidural Space', 'Feasibility Studies', 'Female', 'Fluoroscopy', 'Humans', 'Low Back Pain', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Radiculopathy', 'Reoperation', 'Spinal Diseases', 'Tissue Adhesions', 'Treatment Failure', 'Treatment Outcome']
18,552,347
[['M01.060.116'], ['C23.550.291.500'], ['E01.370.388.250', 'E04.502.250'], ['A02.835.232.834.803.350'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['A02.835.232.834.519'], ['M01....
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
Comparing orthodontic bond failures of light-cured composite resin with chemical-cured composite resin: A 12-month clinical trial.
INTRODUCTION: In this clinical trial, we evaluated and compared bond failure rates of light-cured composite resin vs chemical-cured composite resin for 12 months.METHODS: Twenty-two subjects (356 stainless steel brackets) were included in this study, and a split-mouth design was used to randomly allocate diagonally opp...
['Adolescent', 'Adult', 'Composite Resins', 'Dental Bonding', 'Dental Stress Analysis', 'Equipment Failure', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Light-Curing of Dental Adhesives', 'Male', 'Malocclusion', 'Materials Testing', 'Orthodontic Brackets', 'Orthodontics, Corrective', 'Polymerization', 'Prospective St...
27,476,362
[['M01.060.057'], ['M01.060.116'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.095'], ['E06.308'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998....
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
0
0
1
0
1
1
0
A truncated progesterone receptor (PR-M) localizes to the mitochondrion and controls cellular respiration.
The cDNA for a novel truncated progesterone receptor (PR-M) was previously cloned from human adipose and aortic cDNA libraries. The predicted protein sequence contains 16 unique N-terminal amino acids, encoded by a sequence in the distal third intron of the progesterone receptor PR gene, followed by the same amino acid...
['Base Pairing', 'Blotting, Northern', 'Cell Line, Tumor', 'Cell Respiration', 'Female', 'Humans', 'Mass Spectrometry', 'Membrane Potential, Mitochondrial', 'Mitochondria, Heart', 'Mitochondrial Membranes', 'Mitochondrial Proteins', 'Oxygen', 'Peptides', 'Progestins', 'Protein Transport', 'RNA Interference', 'RNA, Mess...
23,518,922
[['G02.111.570.820.486.100', 'G02.111.611.500', 'G05.360.580.100'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A11.251.210.190', 'A11.251.860.180'], ['G03.197', 'G04.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['G03.295.770.500', 'G04.580.550', 'G07.265.675.550'], ['A11.284.43...
['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Implementation of the extension phase of the Project P.A.T.H.S. in Hong Kong: observations based on the Co-Walker Scheme.
The implementation quality of the Tier 1 Program (Secondary 1 Program) of the Project P.A.T.H.S. in the second year of the Extension Phase was examined in this study, with classroom observations of 218 units in 172 schools. Results demonstrated that the overall level of program adherence was generally high with an aver...
['Adolescent', 'Adolescent Development', 'Adult', 'Faculty', 'Female', 'Guideline Adherence', 'Hong Kong', 'Humans', 'Male', 'Observation', 'Program Evaluation', 'Qualitative Research', 'Quality Improvement', 'Schools', 'Social Problems', 'Students', 'Teaching']
23,446,932
[['M01.060.057'], ['F01.525.049', 'G07.345.374.500'], ['M01.060.116'], ['M01.526.702.250'], ['N04.761.337', 'N05.715.360.395'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.249'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['H01.770.644.241.850'], ['J01.293.754', 'N04.761....
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, ...
0
1
0
0
1
1
1
1
1
1
0
1
1
1
Comparison of the 18-item and 6-item Lubben Social Network Scales with community-dwelling older adults in Mongolia.
This study compares the psychometric properties of two versions of the Lubben Social Network Scale (LSNS-18 and LSNS-6) with community dwelling older adults in Mongolia. We recruited 650 older adult in the capital city of Ulaanbaatar and the country's four rural regions. We used the Geriatric Depression Scale (GDS-15),...
['Aged', 'Female', 'Geriatric Assessment', 'Humans', 'Independent Living', 'Male', 'Mental Health', 'Middle Aged', 'Mongolia', 'Social Isolation', 'Social Networking']
30,998,800
[['M01.060.116.100'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.050.500', 'N01.224.791.550', 'N06.850.505.400.800.550'], ['F02.418', 'N01.400.500'], ['M01.060.116.630'], ['Z01...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Information Science [L]']
0
1
0
0
1
1
0
0
1
0
1
1
1
1
State marker properties of niacin skin sensitivity in ultra-high risk groups for psychosis - An optical reflection spectroscopy study.
Impaired niacin sensitivity (NS) is one of the most replicated findings in untreated schizophrenia, and reflects a disturbance of prostaglandin-mediated pathways in association with deregulated arachidonic acid metabolism, pro-inflammatory activation, and vasomotor function. In ultra-high risk individuals (UHR) increas...
['Adolescent', 'Adult', 'Analysis of Variance', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Niacin', 'Prodromal Symptoms', 'Psychiatric Status Rating Scales', 'Psychotic Disorders', 'Risk', 'Skin', 'Spectrum Analysis', 'Time Factors', 'Young Adult']
28,602,647
[['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['D03.066.515.475', 'D03.383.725.547.475'], ['C23.888.672', 'E01.599'], ['F04.711.513.653'], ['F03.700.675'], ['...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
1
1
1
1
0
0
0
0
1
1
0
Optimizing adult diabetes care in community health.
BACKGROUND AND PURPOSE: Diabetes mellitus is an epidemic. Many organizations and states have established reportable quality care measures. Our organization explored novel ways of chronic disease management. The purpose of this article is to decrease the percentage of patients with a hemoglobin A1c (HbA1c) more than 8%....
['Aged', 'Appointments and Schedules', 'Diabetes Mellitus', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemia', 'Male', 'Middle Aged', 'Minnesota', "Nurse's Role", 'Primary Health Care', 'Prospective Studies', 'Public Health', 'Quality of Health Care', 'Surveys and Questionnaires']
29,846,308
[['M01.060.116.100'], ['N04.452.095'], ['C18.452.394.750', 'C19.246'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['M01.060.116.630'], ['Z01.107.567.875.350.510', 'Z01.107.567.875.510.510'], ['F0...
['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]']
0
1
1
1
1
1
0
1
0
0
0
1
1
1
[Morphology of the optic papilla in glaucoma. I. Primary open-angle glaucoma].
BACKGROUND: Previous studies have shown that the chronic open-angle glaucomas form a heterogeneous spectrum of diseases which have in common an open anterior chamber angle and glaucomatous optic nerve damage. Purpose of this study was to evaluate whether the appearance of the optic disc differs among the various types ...
['Adult', 'Aged', 'Atrophy', 'Female', 'Fluorescein Angiography', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Optic Disk', 'Optic Nerve Diseases', 'Reference Values', 'Retinal Hemorrhage', 'Risk Factors']
10,572,882
[['M01.060.116'], ['M01.060.116.100'], ['C23.300.070'], ['E01.370.370.050.350', 'E01.370.380.250'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['M01.060.116.630'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['C10.292.700', 'C11.640'], ['E05.978.810'], ['C11.290.807', 'C11.76...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]']
1
1
1
0
1
0
1
0
0
0
0
1
1
0
Fucoidan prevents depression-like behavior in rats exposed to repeated restraint stress.
Previous studies have demonstrated that repeated restraint stress in rodents increased depression-like behavior and altered the expression of corticotrophin-releasing factor in the hypothalamus. The current study focused on verifying the impact of fucoidan (FCN) administration on repeated restraint stress-induced behav...
['Animals', 'Antidepressive Agents', 'Behavior, Animal', 'Brain', 'Brain-Derived Neurotrophic Factor', 'Corticosterone', 'Depression', 'Disease Models, Animal', 'Male', 'Motor Activity', 'Polysaccharides', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Restraint, Physical', 'Swimming', 'Time Factors', 'Tyrosine 3-M...
23,090,005
[['B01.050'], ['D27.505.954.427.700.122'], ['F01.145.113'], ['A08.186.211'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['F01.145.126.350'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['F01.145.632', 'G11.427....
['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
1
1
1
1
1
1
1
0
1
0
0
0
0
0
Short Versus Long Cephalomedullary Nails for Pertrochanteric Hip Fracture.
This study compared patients who underwent treatment with short or long cephalomedullary nails with integrated cephalocervical screws and linear compression. Patients with AO/OTA 31-A2 or A3 pertrochanteric fractures treated with either short (n=72) or long (n=97) InterTAN (Smith & Nephew, Memphis, Tennessee) cephalome...
['Adult', 'Aged', 'Bone Nails', 'Bone Screws', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Intramedullary', 'Hip Fractures', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Treatment Outcome']
27,874,910
[['M01.060.116'], ['M01.060.116.100'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300.300'], ['C26.404.061.4...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]']
0
1
1
0
1
0
0
0
0
0
0
1
1
0
Anti-CD40L monoclonal antibody treatment induces long-term, tissue-specific, immunologic hyporesponsiveness to peripheral nerve allografts.
The CD40/CD40L costimulatory pathway plays a crucial role in allograft rejection. The purpose of this study was to determine the effectiveness of anti-CD40L monoclonal antibody (mAb) treatment as a method to induce long-term, tissue-specific, immunologic hyporesponsiveness to peripheral nerve allografts. Sciatic nerve ...
['Animals', 'Antibodies, Monoclonal', 'CD40 Ligand', 'Cytokines', 'Graft Rejection', 'Graft Survival', 'Immunoglobulin G', 'Immunoglobulin M', 'Injections, Intraperitoneal', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Sciatic Nerve', 'Transplantation, Homologous']
18,459,087
[['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.543.550.198', 'D23.529.374.750.124'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.875.545.328'], ['G12.875....
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Somatostatin response to glucose before and after prolonged fasting in lean and obese non-diabetic subjects.
Insulin, glucagon, and somatostatin concentrations were measured in 7 lean and 7 obese non-diabetic subjects over 7 days of fasting. In addition each subject was given a 75 g oral glucose tolerance test after fasts of 12 h and 7 days. In lean subjects complete food deprivation induced a significant decrease in the circ...
['Adult', 'Blood Glucose', 'Body Weight', 'Chromatography, Gel', 'Fasting', 'Female', 'Glucagon', 'Glucose', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Male', 'Obesity', 'Somatostatin']
2,901,133
[['M01.060.116'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.196.181.400.250'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D09.94...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]']
0
1
1
1
1
1
1
0
0
0
0
1
0
0
Effects of lifestyle modification programs on cardiac risk factors.
Medicare conducted a payment demonstration to evaluate the effectiveness of two intensive lifestyle modification programs in patients with symptomatic coronary artery disease: the Dr. Dean Ornish Program for Reversing Heart Disease (Ornish) and Cardiac Wellness Program of the Benson-Henry Mind Body Institute. This repo...
['Aged', 'Body Mass Index', 'Body Weight', 'Coronary Artery Disease', 'Exercise Therapy', 'Fee-for-Service Plans', 'Female', 'Follow-Up Studies', 'Health Expenditures', 'Hospitalization', 'Humans', 'Life Style', 'Male', 'Medicare', 'Patient Education as Topic', 'Prognosis', 'Program Evaluation', 'Risk Factors', 'Risk R...
25,490,202
[['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E02.760.169.06...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]']
0
1
1
0
1
1
1
0
1
0
0
1
1
1
Vagal schwannoma involving esophagus.
A rare case of vagal schwannoma (neurilemoma) with involvement of the distal esophagus is presented. Chronic progressive dysphagia was the only complaint related to the schwannoma. Barium swallow showed narrowing of the distal esophagus. The tumor was embedded in the wall of the esophagus. After biopsy and diagnosis of...
['Aged', 'Cranial Nerve Neoplasms', 'Esophageal Neoplasms', 'Humans', 'Male', 'Neurilemmoma', 'Vagus Nerve']
1,755,691
[['M01.060.116.100'], ['C04.588.614.300', 'C04.588.614.596.240', 'C10.292.225', 'C10.551.360', 'C10.551.775.250'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.595', 'C04.557.580.600.610.595', ...
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
0
0
0
0
0
0
0
0
1
0
0
Imprinting of hepatic estrogen-binding proteins by neonatal androgens.
Previous studies discovered a second class of estrogen-binding proteins distinct from estrogen receptor which exhibited higher capacity, lower affinity (HCLA) binding properties. HCLA sites underwent postpubertal sex differentiation, such that adult male levels were at least 10-fold higher than adult female levels. Neo...
['Animals', 'Carrier Proteins', 'Castration', 'Cytosol', 'Diethylstilbestrol', 'Estradiol', 'Liver', 'Male', 'Rats', 'Rats, Inbred Strains', 'Receptors, Estrogen', 'Sexual Maturation', 'Testosterone', 'Zeranol']
6,832,063
[['B01.050'], ['D12.776.157'], ['E04.270.282', 'E04.950.165'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D02.455.426.559.389.150.700.725.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B0...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Sources of Information and Support for Breastfeeding: Alignment with Centers for Disease Control and Prevention Strategies.
BACKGROUND AND OBJECTIVES: Research consistently supports health benefits of breastfeeding; however, rates in the United States remain below Healthy People 2020 goals. To increase breastfeeding, information and support are needed from multiple sources. Given differences in breastfeeding rates by demographic characteris...
['Adult', 'Breast Feeding', 'Centers for Disease Control and Prevention, U.S.', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Promotion', 'Humans', 'Infant', 'Infant, Newborn', 'Mothers', 'Postpartum Period', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'United States', 'Young Adult']
30,307,320
[['M01.060.116'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['F01.100.150.500', 'N05.300.150.410'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.7...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]']
0
1
0
0
1
1
1
0
1
0
0
1
1
1
Seroprevalence of antibodies to dengue and chikungunya viruses in Thailand.
The abundance of Aedes mosquito species enabled widespread transmission of mosquito-borne chikungunya virus (CHIKV) and dengue virus (DENV) in Southeast Asia. Periodic seroprevalence surveys are therefore necessary to assess the viral burden in the population and the effectiveness of public health interventions. Since ...
['Adult', 'Antibodies, Viral', 'Chikungunya virus', 'Child', 'Child, Preschool', 'Dengue Virus', 'Female', 'Humans', 'Infant', 'Male', 'Seroepidemiologic Studies', 'Thailand']
28,662,144
[['M01.060.116'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B04.820.578.875.054.198'], ['M01.060.406'], ['M01.060.406.448'], ['B04.820.578.344.350.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.950', 'N05.715.360.330.500....
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]']
0
1
0
1
1
0
0
0
0
0
0
1
1
1
[Transurethral ureterolithotripsy using a rigid ureteroscope].
Eighty patients with ureteral stones underwent transurethral ureterolithotripsy using a rigid ureteroscope. In 68 of the patients (85%), the stones were removed successfully. Most of the 12 failures were removed by a percutaneous approach. The main complications of transurethral ureterolithotripsy were high fever (35%)...
['Adult', 'Aged', 'Endoscopy', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Lithotripsy', 'Male', 'Middle Aged', 'Ureteral Calculi', 'Urethra']
3,448,929
[['M01.060.116'], ['M01.060.116.100'], ['E01.370.388.250', 'E04.502.250'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.600', 'E04.943.500'], ['M01.060.116.630'], ['C12.777.725.938.500', 'C12.777.967.374.500', 'C12.777.967.500.851', 'C13.351.968.725.938.500', 'C13.351.968.967.3...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
Children do show negative priming: further evidence for early development of an intact selective control mechanism.
Reactions to stimuli that were shortly before presented as distractors are usually slowed down; this phenomenon is known as negative priming. Negative priming is an accepted index for tapping into selective control mechanisms. Although this effect is well established for adults, it has been claimed that children do not...
['Adult', 'Age Factors', 'Attention', 'Child', 'Color Perception', 'Discrimination, Psychological', 'Female', 'Humans', 'Inhibition, Psychological', 'Male', 'Middle Aged', 'Orientation', 'Pattern Recognition, Visual', 'Reaction Time']
17,723,050
[['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F02.830.104.214'], ['M01.060.406'], ['F02.463.593.932.217'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['M01.060.116.630'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500...
['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
0
1
0
0
1
1
1
0
0
0
0
1
1
0
Did municipal solid waste landfill have obvious influence on polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) in ambient air: A case study in East China.
Municipal solid waste (MSW) landfill was a main way to disposal of MSW and almost 95% of MSW was disposed by landfills in the world. In order to understand the influence of MSW landfill on polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) in surrounding atmosphere, 42 ambient air samples wer...
['Air Pollutants', 'Atmosphere', 'China', 'Dibenzofurans, Polychlorinated', 'Environmental Monitoring', 'Polychlorinated Dibenzodioxins', 'Solid Waste', 'Waste Disposal Facilities']
28,223,077
[['D27.888.284.101'], ['G16.500.275.063', 'N06.230.300.100'], ['Z01.252.474.164'], ['D02.309.250', 'D03.633.300.258.500'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.309.500.450', 'D03.633.300.786'], ['D20.944.730', 'N06.850.460.710.730'], ['N06.850.780.200.800.800.900.449', 'N06.850.860.510.900.700']]
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]']
0
0
0
1
0
0
1
0
0
0
0
0
1
1
Enhancement of bone healing using non-glycosylated rhBMP-2 released from a fibrin matrix in dogs and cats.
OBJECTIVES: To test a non-glycosylated recombinant human bone morphogenetic protein-2 (ngly-rhBMP-2)/fibrin composite, which has been shown experimentally to enhance healing of bone defects in rodents, in a clinical case series of dogs and cats undergoing treatment for fracture non-unions and arthrodesis.METHODS: A ngl...
['Animals', 'Bone Morphogenetic Protein 2', 'Bone Morphogenetic Proteins', 'Bone Substitutes', 'Cats', 'Dogs', 'Female', 'Fibrin', 'Fracture Fixation', 'Fracture Healing', 'Male', 'Prospective Studies', 'Transforming Growth Factor beta', 'Treatment Outcome']
15,682,735
[['B01.050'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['D25.130.325', 'J01.637.051.130.325'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.750.250.216.200'], ['D12.776.124.270'], ['E04...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
0
1
0
1
1
0
1
0
0
1
0
0
1
0
MYND-less splice variants of AML1-MTG8 (RUNX1-CBFA2T1) are expressed in leukemia with t(8;21).
The AML1-MTG8 fusion gene is generated by chromosome translocation t(8;21), which is frequently observed in acute myeloid leukemia. The fusion gene produces a chimeric transcription factor that suppresses the expression of AML1-target genes via the MTG8 part of the chimeric protein, which is thought to be the primary c...
['Alternative Splicing', 'Base Sequence', 'Cell Line, Tumor', 'Chromosomes, Human, Pair 21', 'Chromosomes, Human, Pair 8', 'Core Binding Factor Alpha 2 Subunit', 'DNA-Binding Proteins', 'Female', 'Gene Deletion', 'Genetic Variation', 'Humans', 'Leukemia', 'Male', 'Molecular Sequence Data', 'Proto-Oncogene Proteins', 'R...
15,723,339
[['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['D12.776.930.155.200.200...
['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]']
1
1
1
1
0
0
1
0
0
0
1
0
0
0
Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic.
Some reference opioids containing the Dmt-Tic pharmacophore, especially the delta agonists H-Dmt-Tic-Gly-NH-Ph (1) and H-Dmt-Tic-NH-(S)CH(CH2-COOH)-Bid (4) (UFP-512) were evaluated for the influence of the substitution of Gly with aspartic acid, its chirality, and the importance of the -NH-Ph and N(1)H-Bid hydrogens in...
['Analgesics', 'Animals', 'Dipeptides', 'Mice', 'Receptors, Opioid, delta', 'Receptors, Opioid, mu', 'Structure-Activity Relationship', 'Tail', 'Tetrahydroisoquinolines']
18,680,274
[['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D12.644.456.345'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.543.750.695.620.200', 'D12.776.543.750.720.600.610.200', 'D12.776.543.750.750.555.610.200'], ['D12.776.543.750.695.620.550', 'D12.776.543.750.720.600.610.550', 'D12.776.543.750.7...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development.
The mouse genome contains at least three copies of sequences homologous to the "paired box", a conserved domain in several Drosophila segmentation genes of the pair-rule and segment polarity classes. Overlapping phages were isolated from two different genomic libraries using the Drosophila gooseberry distal paired box ...
['Amino Acid Sequence', 'Animals', 'Base Sequence', 'DNA', 'Gene Expression Regulation', 'Genes, Homeobox', 'Mice', 'Molecular Sequence Data', 'Nucleic Acid Hybridization', 'RNA', 'Sequence Homology, Nucleic Acid']
2,453,291
[['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['G05.308'], ['G05.360.340.024.340.230.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['E05.393.661', 'G02.111.611'], ['D13.444.735'], ['G02.111.810.550', 'G05....
['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
1
1
0
1
0
0
0
1
0
0
0
Evaluation of research studies. Part I: Randomized trials.
Clinical practice is often based on the results of research. Critical evaluation of research studies is important if appropriate conclusions are to be drawn. In this series of columns, we review principles of research methodology and statistical analysis. Our intent is to assist certified nurse-midwives in understandin...
['Humans', 'Nurse Midwives', 'Outcome Assessment, Health Care', 'Randomized Controlled Trials as Topic']
1,403,175
[['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.650.648.762', 'N02.360.650.648.762'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500']]
['Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
0
1
0
0
1
0
0
0
1
1
0
RNA quality in fresh-frozen gastrointestinal tumor specimens-experiences from the tumor and healthy tissue bank TU Dresden.
The term "pre-analytics" summarizes all procedures concerned with specimen collection or processing as well as logistical aspects like transport or storage of tissue specimens. All or these variables as well as tissue-specific characteristics affect sample quality. While certain parameters like warm ischemia or tissue-...
['Cell Fractionation', 'Freezing', 'Gastrointestinal Neoplasms', 'Gastrointestinal Tract', 'Germany', 'Humans', 'Intraoperative Period', 'Organ Specificity', 'Perioperative Period', 'RNA', 'Retrospective Studies', 'Specimen Handling', 'Tissue Banks']
25,636,432
[['E05.242.251'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['A03.556'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['G07.650'], ['E04.614', 'N02.421.585.753'], ['D13.444.735'], ['E05.318.372.5...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]']
1
1
1
1
1
0
1
0
0
0
0
0
1
1
Aminoglycoside-mediated promotion of translation readthrough occurs through a non-stochastic mechanism that competes with translation termination.
Attempts have been made to treat nonsense-associated genetic disorders by chemical agents and hence an improved mechanistic insight into the decoding of readthrough signals is essential for the identification and characterisation of factors for the treatment of these disorders. To identify either novel compounds or gen...
['Aminoglycosides', 'Base Sequence', 'Casein Kinase Ialpha', 'Codon, Nonsense', 'Codon, Terminator', 'High-Throughput Nucleotide Sequencing', 'Humans', 'NM23 Nucleoside Diphosphate Kinases', 'Nucleic Acid Conformation', 'Oxadiazoles', 'Peptide Chain Termination, Translational', 'Protein Biosynthesis', 'Protein Synthesi...
29,177,465
[['D09.408.051'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D05.500.117.750.100', 'D08.811.913.696.620.682.700.140.300.100', 'D12.776.476.081.750.100', 'D12.776.476.150.299.100'], ['D13.444.735.544.355.250.235', 'G05.360.335.355.250.235', 'G05.365.590.195'], ['D13.444.735.544.355.250', 'G05.360.335.3...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
0
1
1
0
1
0
0
0
1
0
0
0
Transfer of memory cells into antigen-pretreated hosts. II. Influence of localized antigen on the migration of specific memory B cells.
Following i.v. injection, 2,4,6-trinitrophenol (TNP)-primed memory cells localized in recipient lymph nodes draining a footpad injection of TNP-hemocyanin (TNP-KLH) in greater numbers than in contralateral nodes draining a p-azobenzenearsonate-coupled KLH injection. Such hapten-specific, unilateral memory B cell locali...
['Animals', 'Antibodies', 'Antigen-Antibody Complex', 'Antigens', 'B-Lymphocytes', 'Cattle', 'Cell Movement', 'Cyclophosphamide', 'Epitopes', 'Hemocyanins', 'Immunization, Passive', 'Immunologic Memory', 'Kinetics', 'Lymph Nodes', 'Mice', 'Mice, Inbred Strains', 'Serum Albumin, Bovine', 'Splenectomy', 'Trinitrobenzenes...
6,173,238
[['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D23.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.38...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Treating early-stage breast cancer: hospital characteristics associated with breast-conserving surgery.
Despite growing acceptance of the fact that women with early-stage breast cancer have similar outcomes with lumpectomy plus radiation as with mastectomy, many studies have revealed the uneven adoption of such breast-conserving surgery. Discharge data from the Hospital Cost and Utilization Project, representing multiple...
['Aged', 'Breast Neoplasms', 'Female', 'Health Services Research', 'Hospital Bed Capacity', 'Hospitals, General', 'Hospitals, Teaching', 'Humans', 'Mastectomy, Radical', 'Mastectomy, Segmental', 'Mastectomy, Simple', 'Middle Aged', 'United States']
7,573,632
[['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['N02.278.306.472'], ['N02.278.421.389'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466.678'], ['E04.466.701'], ['E04.466.754'], ['M01.060.116.630'], ['Z01.10...
['Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]']
0
1
1
0
1
0
0
1
0
0
0
1
1
1
What do coronary artery disease patients think about their treatments? An assessment of patients' treatment representations.
This article investigates patients' beliefs about the intervention offered to manage their illness. Coronary artery disease (CAD) patients, 70 of whom were undergoing medication, 71 to undergo angioplasty and 73 to undergo surgery, completed a 58-item questionnaire regarding their treatment beliefs. Responses were subj...
['Aged', 'Coronary Artery Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Satisfaction', 'United Kingdom']
18,420,766
[['M01.060.116.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['Z01.542.363']]
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]']
0
1
1
0
0
1
0
0
0
0
0
1
1
1
Effect of interleukin 6 -174G>C gene polymorphism on opioid requirements after total hip replacement.
OBJECTIVE: In recent years, increasing attention has been paid to the contribution of genetic factors to variability in patient pain threshold and the efficacy of pain management. One of the genes implicated in pain pathology and treatment response is interleukin 6 (IL6). The aim of the present study was to evaluate th...
['Adult', 'Aged', 'Aged, 80 and over', 'Analgesia, Patient-Controlled', 'Analgesics, Non-Narcotic', 'Analgesics, Opioid', 'Arthroplasty, Replacement, Hip', 'Female', 'Humans', 'Interleukin-6', 'Male', 'Middle Aged', 'Pain, Postoperative']
27,048,515
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E03.091.120'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.1...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]']
0
1
1
1
1
0
0
0
0
0
0
1
0
0
GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion.
The establishment of synaptic connections requires precise alignment of pre- and postsynaptic terminals. The glial cell line-derived neurotrophic factor (GDNF) receptor GFRalpha1 is enriched at pre- and postsynaptic compartments in hippocampal neurons, suggesting that it has a function in synapse formation. GDNF trigge...
['Analysis of Variance', 'Animals', 'Brain', 'Cell Adhesion', 'Cell Differentiation', 'Cell Membrane', 'Cells, Cultured', 'Embryo, Mammalian', 'Gene Expression', 'Glial Cell Line-Derived Neurotrophic Factor', 'Glial Cell Line-Derived Neurotrophic Factor Receptors', 'Ligands', 'Mice', 'Mice, Knockout', 'Nerve Growth Fac...
17,310,246
[['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.186.211'], ['G04.022'], ['G04.152'], ['A11.284.149'], ['A11.251'], ['A16.254'], ['G05.297'], ['D12.644.276.860.381.500', 'D12.776.467.860.381.500', 'D12.776.631.600.381.500', 'D23.529.850.381.500'], ['D12.776.395.550.448.400', 'D12.7...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
0
0
0
0
0
1
0
Citrullinemia. Clinical experience with 23 cases.
A retrospective study was performed on the clinical outcome of 23 patients with citrullinemia diagnosed during the last 20 years in our clinic. The study group consisted of 13 patients with the neonatal form of the disease, four patients with the subacute form, five patients with the late-onset form and one with the as...
['Adolescent', 'Age of Onset', 'Amino Acid Metabolism, Inborn Errors', 'Arginine', 'Argininosuccinate Synthase', 'Benzoates', 'Benzoic Acid', 'Child', 'Child, Preschool', 'Citrulline', 'Diet, Protein-Restricted', 'Exchange Transfusion, Whole Blood', 'Female', 'Food Preservatives', 'Humans', 'Infant', 'Infant, Newborn',...
9,677,723
[['M01.060.057'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['C16.320.565.100', 'C18.452.648.100'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D08.811.464.259.300'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['D02.241.223.100.120', 'D02.455.426.559.389.127.117'], ['M01.060.406'], ['M01.060...
['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanit...
0
1
1
1
1
0
1
0
1
1
0
1
1
0
Effect of initial microbial density on inactivation of Giardia muris by ozone.
Inactivation of microorganisms by disinfectants frequently shows non-linear behavior on a semilogarithmic plot of log survival ratio versus time. A number of models have been developed to depict these deviations from Chick's Law. Some of the models predict that the log survival ratio (at a particular disinfectant dose ...
['Animals', 'Disinfectants', 'Giardia', 'Kinetics', 'Models, Theoretical', 'Oxidants, Photochemical', 'Ozone', 'Population Dynamics', 'Survival Analysis', 'Water Microbiology', 'Water Purification']
12,767,301
[['B01.050'], ['D27.505.954.122.425', 'D27.720.274'], ['B01.237.385'], ['G01.374.661', 'G02.111.490'], ['E05.599'], ['D27.720.642.631', 'D27.888.569.540.631'], ['D01.362.670.600'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['H01.158.273.540...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]']
0
1
0
1
1
0
1
1
1
0
0
0
1
0
Impact of Physiological Signals Acquisition in the Emotional Support Provided in Learning Scenarios.
Physiological sensors can be used to detect changes in the emotional state of users with affective computing. This has lately been applied in the educational domain, aimed to better support learners during the learning process. For this purpose, we have developed the AICARP (Ambient Intelligence Context-aware Affective...
['Awareness', 'Biosensing Techniques', 'Emotions', 'Galvanic Skin Response', 'Heart Rate', 'Humans', 'Learning', 'Monitoring, Physiologic', 'Temperature', 'User-Computer Interface']
31,627,443
[['F02.463.188.150'], ['E05.601.043'], ['F01.470'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['E01.370.520'], ['G01.906.595', 'G16.500.275.063.725.710'...
['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]']
0
1
0
0
1
1
1
0
0
0
1
0
1
0
Duration of labor induction in nulliparous women at term: how long is long enough?
We evaluated the relationship between duration of labor induction and successful vaginal delivery (VD) in nulliparous women at term. Nulliparous women with singleton pregnancies > or = 37 weeks who underwent labor induction at a single institution were studied. Exclusion criteria were nonvertex presentation, stillbirth...
['Adolescent', 'Adult', 'Female', 'Humans', 'Labor, Induced', 'Labor, Obstetric', 'Middle Aged', 'Parity', 'Pregnancy', 'Pregnancy Outcome', 'Term Birth']
18,548,392
[['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.520.252.968'], ['G08.686.784.769.326'], ['M01.060.116.630'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['G08.686.784.769.490.500']]
['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
0
1
0
0
1
0
1
0
0
0
0
1
1
0
Six-minute walk distance predictors, including CT scan measures, in the COPDGene cohort.
BACKGROUND: Exercise tolerance in COPD is only moderately well predicted by airflow obstruction assessed by FEV(1). We determined whether other phenotypic characteristics, including CT scan measures, are independent predictors of 6-min walk distance (6MWD) in the COPDGene cohort.METHODS: COPDGene recruits non-Hispanic ...
['Aged', 'Aged, 80 and over', 'Emphysema', 'Exercise Tolerance', 'Female', 'Forced Expiratory Volume', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Disease, Chronic Obstructive', 'Smoking', 'Spirometry', 'Time Factors', 'Tomography, X-Ray Computed', 'Walking']
21,960,696
[['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.325'], ['G11.427.680.270'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C08.381.495.389'], ['F01.145.805'], ['E01.370.386.700.750'], ['G01.910.857'], ['E01.370.350.350.810', 'E01.370.350....
['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
0
1
1
0
1
1
1
0
1
0
0
1
0
0
The Dark Side of Internet Use: Two Longitudinal Studies of Excessive Internet Use, Depressive Symptoms, School Burnout and Engagement Among Finnish Early and Late Adolescents.
Recent research shows an increased concern with well-being at school and potential problems associated with students' use of socio-digital technologies, i.e., the mobile devices, computers, social media, and the Internet. Simultaneously with supporting creative social activities, socio-digital participation may also le...
['Adolescent', 'Adolescent Behavior', 'Depression', 'Female', 'Finland', 'Humans', 'Internet', 'Longitudinal Studies', 'Male', 'Mental Health', 'Psychology, Adolescent', 'Schools', 'Stress, Psychological', 'Students']
27,138,172
[['M01.060.057'], ['F01.145.022'], ['F01.145.126.350'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['F02.418', 'N01.400.500'], ['F04.096.628.065'], ['I02.783', 'J03.832'], ['F01...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]']
0
1
0
0
1
1
0
0
1
1
1
1
1
1
Effect of an impaired oral stage on swallowing in patients with Parkinson's disease.
We investigated the swallowing function in patients with Parkinson's disease (PD) using deteriorated tongue control because patients with PD frequently exhibit an impaired oral stage of swallowing and the tongue movement affects oral and pharyngeal stage. In total, 201 patients with PD (106 men, 95 women; mean age 70·6...
['Aged', 'Barium', 'Contrast Media', 'Deglutition', 'Deglutition Disorders', 'Female', 'Fluoroscopy', 'Humans', 'Larynx', 'Male', 'Oral Stage', 'Parkinson Disease', 'Pharynx', 'Tongue', 'Videotape Recording']
28,644,574
[['M01.060.116.100'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['D27.505.259.500', 'D27.720.259'], ['G10.261.178'], ['C06.405.117.119', 'C09.775.174'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.329'], ['F01.752.747.722.626', 'F02.739.794.793.626...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]']
1
1
1
1
1
1
1
0
0
1
1
1
0
0
Cadmium stress studies: media development, enrichment, consortia analysis, and environmental relevance.
The effects of Cadmium (Cd) toxicity on bacterial consortia originating from an-aerobic sewage sludge and cultivated under differing enrichment conditions were studied. Cultures were enriched in minimal media developed specifically for Cd stress studies. At inoculation all Cd was soluble in free ion or chelated form. E...
['Bacteria', 'Cadmium', 'Cell Division', 'Chelating Agents', 'Culture Media', 'DNA, Bacterial', 'Drug Resistance, Bacterial', 'Hydrogen-Ion Concentration', 'Klebsiella', 'RNA, Bacterial', 'RNA, Ribosomal, 16S', 'Soil', 'Soil Microbiology', 'Soil Pollutants']
12,572,683
[['B03'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.212'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['G02.300'], ['B03.44...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]']
0
1
0
1
1
0
1
1
0
0
0
0
1
0
Novel lansoprazole-loaded nanoparticles for the treatment of gastric acid secretion-related ulcers: in vitro and in vivo pharmacokinetic pharmacodynamic evaluation.
The objective of this study is to combine nanoparticle design and enteric coating technique to sustain the delivery of an acid-labile drug, lansoprazole (LPZ), in the treatment of acid reflux disorders. Lansoprazole-loaded Eudragit® RS100 nanoparticles (ERSNP-LPZ) as well as poly(lactic-co-glycolic acid) (PLGA) nanopar...
['Animals', 'Anti-Ulcer Agents', 'Caco-2 Cells', 'Gastric Acid', 'Humans', 'Intestinal Absorption', 'Intestinal Mucosa', 'Lansoprazole', 'Male', 'Nanoparticles', 'Particle Size', 'Rats', 'Rats, Wistar', 'Stomach Ulcer', 'Tablets, Enteric-Coated']
24,519,468
[['B01.050'], ['D27.505.954.483.203'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['A12.200.307.603'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['A03.556.124.369', 'A1...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]']
1
1
1
1
0
0
1
0
0
1
0
0
0
0
Patterns histopathologic of Fox-Fordyce disease.
Fox-Fordyce disease is an uncommon condition that is biopsied even less commonly. Since the publication of Shelley and Levy, in 1956, the disease is regarded widely to be "apocrine miliaria", an analogue of eccrine miliaria. Histopathologically, an "intraepidermal sweat retention vesicle" is considered the only feature...
['Dermatology', 'Fox-Fordyce Disease', 'History, 20th Century', 'Sweat Glands']
15,618,931
[['H02.403.225'], ['C17.800.946.492.285'], ['K01.400.504.968'], ['A10.336.899', 'A17.815.830']]
['Disciplines and Occupations [H]', 'Diseases [C]', 'Humanities [K]', 'Anatomy [A]']
1
0
1
0
0
0
0
1
0
0
0
0
0
0
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix.
The small guanosine triphosphatase Ran loaded with GTP (RanGTP) can stimulate assembly of the type V intermediate filament protein lamin B into a membranous lamin B spindle matrix, which is required for proper microtubule organization during spindle assembly. Microtubules in turn enhance assembly of the matrix. Here we...
['Animals', 'Aurora Kinases', 'Biological Assay', 'Carrier Proteins', 'Chromatin', 'Dyneins', 'Extracellular Matrix', 'Humans', 'Kinetochores', 'Lamin Type B', 'Laminin', 'Male', 'Microtubule-Associated Proteins', 'Microtubules', 'Mitosis', 'Morphogenesis', 'Ovum', 'Protein Binding', 'Protein-Serine-Threonine Kinases',...
19,198,602
[['B01.050'], ['D08.811.913.696.620.682.700.103', 'D12.776.167.049'], ['E05.091'], ['D12.776.157'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D08.811.277.040.013.500.063', 'D08.811.277.040.025.024.063', 'D08.811.277.040.025.193.249', 'D12.776.157.025.750.063', 'D12.776.220.600.200...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
[Parallel DNA double helices. II. Conformational analysis of regular helices having a second order axis of symmetry].
Conformational analysis of double helices of DNA with parallel arranged sugar-phosphate chains connected by twofold symmetry has been performed. Homopolymers poly(dA).poly(dA), poly(dC).poly(dC), poly(dG).poly(dG) and poly(dT).poly(dT) were studied. For each of the homopolymers all variants of H-bond pairing were check...
['DNA', 'Nucleic Acid Conformation']
2,586,507
[['D13.444.308'], ['G02.111.570.820.486', 'G05.360.580']]
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
0
0
0
1
0
0
1
0
0
0
0
0
0
0
Gallic acid-based small-molecule inhibitors of JC and BK polyomaviral infection.
JCPyV and BKPyV are common human polyomaviruses that cause lifelong asymptomatic persistent infections in their hosts. In immunosuppressed individuals, increased replication of JCPyV and BKPyV cause significant disease. JCPyV causes a fatal and rapidly progressing demyelinating disease known as progressive multifocal l...
['Antiviral Agents', 'BK Virus', 'Cell Line', 'Drug Evaluation, Preclinical', 'Gallic Acid', 'Humans', 'JC Virus', 'Virus Attachment']
24,960,120
[['D27.505.954.122.388'], ['B04.280.210.700.615.100', 'B04.613.204.670.615.100'], ['A11.251.210'], ['E05.290.750', 'E05.337.550'], ['D02.241.223.100.300.200', 'D02.241.511.390.200', 'D02.455.426.559.389.127.281.200', 'D02.455.426.559.389.657.410.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.280.210.700....
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
[Preliminary study of the therapeutic effect of superoxide dismutase in 7 cases of Beh?et's disease].
Neutrophils of patients with Beh?et's syndrome generate increased amounts of oxygen free radicals. This phenomenon is inhibited by superoxide dismutase (SOD) and catalase and is implicated in vasculitis. We treated seven patients with active Beh?et's syndrome by CuZn SOD intramuscularis with dramatic improvement of cli...
['Adult', 'Behcet Syndrome', 'Female', 'Humans', 'Injections, Intramuscular', 'Male', 'Middle Aged', 'Superoxide Dismutase', 'Time Factors']
3,084,046
[['M01.060.116'], ['C07.465.075', 'C11.941.879.780.880.200', 'C14.907.940.100', 'C16.320.382.250', 'C17.800.827.368.250', 'C17.800.862.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['M01.060.116.630'], ['D08.811.682.881'], ['G01.910.857']]
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
0
0
0
0
1
0
0
Family Nursing Therapeutic Conversations in Heart Failure Outpatient Clinics in Denmark: Nurses' Experiences.
As part of the Heart Failure Family Trial presently being conducted in Denmark, this qualitative process evaluation explored the perceptions of seven practicing cardiac nurses who offered family nursing therapeutic conversations (FNTC) to families in three heart failure outpatient clinics. FNTC were guided by the Calga...
['Adult', 'Aged', 'Aged, 80 and over', 'Attitude of Health Personnel', 'Communication', 'Denmark', 'Family', 'Family Nursing', 'Female', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Nurse-Patient Relations', 'Nursing Staff', 'Outpatients', 'Qualitative Research']
27,165,753
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.050', 'N05.300.100'], ['F01.145.209', 'L01.143'], ['Z01.542.816.124'], ['F01.829.263', 'I01.880.853.150'], ['H02.478.676.218'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.829.401.650.600', 'N05.30...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]']
0
1
1
0
0
1
0
1
1
0
1
1
1
1
Rostral Ventrolateral Medulla EP3 Receptor Mediates the Sympathoexcitatory and Pressor Effects of Prostaglandin E2 in Conscious Rats.
Whereas few studies have dealt with the central sympathoexcitatory action of the inflammatory prostanoid prostaglandin E2 (PGE2), there is no information on the expression and cardiovascular function of different PGE2 (EP) receptors in one of the major cardiovascular-regulating nuclei, the rostral ventrolateral medulla...
['Animals', 'Blood Pressure', 'Consciousness', 'Dinoprostone', 'Gene Expression Regulation', 'Glutamic Acid', 'Male', 'Medulla Oblongata', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'NADPH Oxidases', 'Nitric Oxide Synthase Type I', 'Oxidative Stress', 'PC12 Cells', 'Phosphorylation', 'R...
27,572,469
[['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['F02.463.188.409', 'F02.830.233'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['G05.308'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['A08.186.211.132.810.591.500'], ['D08.811.913.696.620.682.700.567.249.500', 'D12....
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]']
1
1
0
1
1
1
1
0
0
0
0
0
0
0
Hypoxic Stress Induced by Hydralazine Leads to a Loss of Blood-Brain Barrier Integrity and an Increase in Efflux Transporter Activity.
Understanding cellular and molecular mechanisms induced by hypoxic stress is crucial to reduce blood-brain barrier (BBB) disruption in some neurological diseases. Since the brain is a complex organ, it makes the interpretation of in vivo data difficult, so BBB studies are often investigated using in vitro models. Howev...
['Animals', 'Biological Transport', 'Biomarkers', 'Blood-Brain Barrier', 'Cell Survival', 'Hydralazine', 'Hypoxia', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Membrane Transport Proteins', 'Metabolic Networks and Pathways', 'Oxidative Stress', 'Permeability', 'Rats', 'Tight Junction Proteins']
27,337,093
[['B01.050'], ['G03.143'], ['D23.101'], ['A07.035', 'A08.186.211.035'], ['G04.346'], ['D03.383.710.605.500'], ['C23.888.852.079'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['D12.776.157.530', 'D12.776.543.585'], ['G03.493'], ['G03.673', 'G07.775.750'], ['G02.723'], ['B01.050.150.900.649.313.992.635.505.7...
['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
The determination at housing of exposure to gastrointestinal nematode infections in first-grazing season calves.
Various parameter estimates were assessed at housing in calves that had been exposed to gastrointestinal nematodes during a first grazing season. The analysis involved 41 groups of first grazing season (FGS) calves on 15 different farms in Belgium and comprised groups that had received chemoprophylactic treatment and u...
['Abomasum', 'Animals', 'Anthelmintics', 'Antibodies, Helminth', 'Belgium', 'Cattle', 'Cattle Diseases', 'Enzyme-Linked Immunosorbent Assay', 'Feces', 'Female', 'Gastrointestinal Diseases', 'Host-Parasite Interactions', 'Male', 'Ostertagia', 'Ostertagiasis', 'Parasite Egg Count', 'Pepsinogen A', 'Regression Analysis', ...
9,950,338
[['A13.869.106'], ['B01.050'], ['D27.505.954.122.250.075'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['Z01.542.115'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', '...
['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
0
0
0
1
1
[Evaluation of efficacy and clinical impact of FDG-PET in patients with suspicion of recurrent colorectal cancer].
AIMS: To evaluate the utility and clinical impact of Positron Emission Tomography with FDG (FDG-PET) in patients with suspected recurrent colorectal cancer (RCR).MATERIALS AND METHODS: Eighty five (85) patients with suspicion of RCR (Group A: 35 for increased tumor markers and negative imaging tests, Group B: 25 operab...
['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Case Management', 'Colorectal Neoplasms', 'Combined Modality Therapy', 'False Negative Reactions', 'False Positive Reactions', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Liver Neoplasms', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male',...
15,450,136
[['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['N04.590.233.624.250'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E02.186'], ['E01.354.340'], ['E01.354.506']...
['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
0
0
0
0
1
1
0
An investigation of the optimization of search logic for the MEDLINE database.
One of the key variables in the optimization of the retrieval process is the logic imposed on a set of query terms. If the query is small, a combinatorial algorithm can be employed to identify search expressions having an optimal logical form. An experiment is described in which this was done for queries expressed agai...
['Algorithms', 'Efficiency', 'Information Storage and Retrieval', 'Logic', 'MEDLINE', 'Research Design', 'United Kingdom', 'User-Computer Interface']
10,111,575
[['G17.035', 'L01.224.050'], ['F02.784.692.351', 'N04.452.209'], ['L01.313.500.750.280', 'L01.470'], ['K01.752.448'], ['L01.313.500.750.280.710.500', 'L01.313.500.750.280.750.500', 'L01.313.500.750.300.188.300.650.500', 'L01.313.500.750.300.710.500', 'L01.313.500.750.300.742.650.500', 'L01.470.750.500.650.500'], ['E05....
['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]']
0
0
0
0
1
1
1
1
0
0
1
0
1
1
Eugenol potentiates cisplatin anti-cancer activity through inhibition of ALDH-positive breast cancer stem cells and the NF-êB signaling pathway.
Triple-negative breast tumors are very aggressive and contain relatively high proportion of cancer stem cells, and are resistant to chemotherapeutic drugs including cisplatin. To overcome these limitations, we combined eugenol, a natural polyphenolic molecule, with cisplatin to normalize cisplatin mediated toxicity and...
['Aldehyde Dehydrogenase', 'Animals', 'Antineoplastic Agents', 'Breast', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cisplatin', 'Drug Synergism', 'Eugenol', 'Female', 'Humans', 'Mice, Nude', 'NF-kappa B', 'Neoplastic Stem Cells', 'Signal Transduction', 'Triple Negative Breast Neoplasms']
29,073,729
[['D08.811.682.657.163.249'], ['B01.050'], ['D27.505.954.248'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G07.690.773.968.477'], ['D02.241.223.200.054.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study.
OBJECTIVE: Identify clinical features predictive of Lewy body pathology in Alzheimer's disease (AD) patients in an ongoing longitudinal clinicopathologic study.MATERIAL AND METHODS: We queried the Arizona Study of Aging and Neurodegenerative Disorders (AZSAND) database for dementia cases with AD pathology (1997-2015). ...
['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Brain', 'Databases, Factual', 'Female', 'Humans', 'Lewy Bodies', 'Male', 'Neuropsychological Tests', 'Prospective Studies', 'Psychiatric Status Rating Scales']
30,229,861
[['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.420.460'], ['F04.711.513'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.6...
['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
1
1
1
0
1
1
0
0
0
0
1
1
1
0
Time trends in socioeconomic differences in incidence rates of cancers of gastro-intestinal tract in Finland.
BACKGROUND: The magnitude of socioeconomic differences in health varies between societies, and over time within a given society. We studied the association between social class and incidence of cancers of the gastro-intestinal tract over time in a large cohort in Finland.METHODS: We studied social class variation among...
['Aged', 'Cardia', 'Colonic Neoplasms', 'Esophageal Neoplasms', 'Finland', 'Gallbladder Neoplasms', 'Gastrointestinal Neoplasms', 'Heart Neoplasms', 'Humans', 'Incidence', 'Intestinal Neoplasms', 'Liver Neoplasms', 'Middle Aged', 'Pancreatic Neoplasms', 'Rectal Neoplasms', 'Social Class', 'Socioeconomic Factors']
17,144,908
[['M01.060.116.100'], ['A03.556.875.875.163'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['Z01.542.816.186'], ['C04.588....
['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
1
1
1
0
1
0
0
0
1
0
0
1
1
1
A theoretical framework for comparing noise characteristics of spectral, differential phase-contrast and spectral differential phase-contrast x-ray imaging.
Spectral and grating-based differential phase-contrast (DPC) x-ray imaging are two emerging technologies that offer additional information compared with conventional attenuation-based x-ray imaging. In the case of spectral imaging, energy-resolved measurements allow the generation of material-specific images by exploit...
['Algorithms', 'Humans', 'Image Processing, Computer-Assisted', 'Models, Theoretical', 'Phantoms, Imaging', 'Radiography', 'Signal-To-Noise Ratio']
31,995,518
[['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.599'], ['E07.671'], ['E01.370.350.700'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750']]
['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
0
0
1
0
1
0
0
0
1
0
1
0
Glycerol-induced development of catalytically active conformation of Crotalus adamanteus L-amino acid oxidase in vitro.
The reconstitutable apoprotein of Crotalus adamanteus L-amino acid oxidase was prepared using hydrophobic interaction chromatography. After reconstitution with flavin adenine dinucleotide, the resulting protein was inactive, with a perturbed conformation of the flavin binding site. Subsequently, a series of cosolvent-d...
['Amino Acid Oxidoreductases', 'Animals', 'Apoenzymes', 'Crotalid Venoms', 'Enzyme Stability', 'Flavin-Adenine Dinucleotide', 'Glycerol', 'Kinetics', 'L-Amino Acid Oxidase', 'Protein Conformation', 'Spectrophotometry', 'Viperidae']
8,755,511
[['D08.811.682.664.500'], ['B01.050'], ['D08.811.255.500', 'D12.776.070.290'], ['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['E05.916.360', 'G02.111.700.500'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', 'D08.211.474.650.249', 'D13.695.667.138.506', 'D13.695.827.068....
['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
Association of angiotensin-converting enzyme gene dimorphisms with severity of lupus disease.
Angiotensin-converting enzyme (ACE) plays an important role in the development of systemic lupus erythematosus (SLE) because its end-product, angiotensin II, plays an integral role in the regulatory system responsible for endothelial control and vascular tone, systems that are commonly affected in patients with SLE. Ad...
['DNA', 'Female', 'Genetic Variation', 'Genotype', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Pakistan', 'Peptidyl-Dipeptidase A', 'Polymorphism, Single Nucleotide', 'Reference Values', 'Retrospective Studies', 'Severity of Illness Index']
18,711,292
[['D13.444.308'], ['G05.365'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['Z01.252.245.723'], ['D08.811.277.656.350.350.687'], ['G05.365.795.598'], ['E05.978.810'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330....
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
1
1
1
0
1
0
0
0
0
0
1
1
Biomechanics of quadrupedal walking: how do four-legged animals achieve inverted pendulum-like movements?
Walking involves a cyclic exchange of gravitational potential energy and kinetic energy of the center of mass. Our goal was to understand how the limbs of walking quadrupeds coordinate the vertical movements of the fore and hind quarters to produce these inverted pendulum-like movements. We collected kinematic and grou...
['Animals', 'Biomechanical Phenomena', 'Dogs', 'Forelimb', 'Gait', 'Hindlimb', 'Models, Biological', 'Time Factors', 'Walking']
15,339,951
[['B01.050'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.750.250.216.200'], ['A13.395'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['A13.473'], ['E05.599.395'], ['G01.910.857'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.450.642.845.940']]
['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
1
1
0
0
1
0
1
0
1
0
0
0
0
0
Glucose and amino acid metabolism in chick telencephalon slices: changes with incubation conditions and animals' development.
Glucose and amino acid metabolism in 1- and 30-day-old chick telencephalon slices was studied in two incubation media in the presence or in the absence of a continuous oxygenation. Medium 1 has a composition and a tonicity similar to cerebrospinal fluid, medium 2 is hypertonic and does not contain any K+ ions. The inco...
['Aging', 'Amino Acids', 'Animals', 'Blood Glucose', 'Chickens', 'Culture Techniques', 'Telencephalon']
3,614,515
[['G07.345.124'], ['D12.125'], ['B01.050'], ['D09.947.875.359.448.500'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.481.500'], ['A08.186.211.200.885']]
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis.
Although much has been learned regarding the importance of p38 mitogen-activated protein kinase in inflammatory and stress responses, relatively little is known concerning its role in differentiation processes. Recently, we demonstrated that p38 mitogen-activated protein kinase activity is necessary for the differentia...
['3T3 Cells', 'Adipocytes', 'Amino Acid Substitution', 'Animals', 'Apoptosis', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Cell Differentiation', 'Enzyme Induction', 'Fibroblasts', 'Glutamic Acid', 'Isopropyl Thiogalactoside', 'JNK Mitogen-Activated Protein Kinases', 'MAP Kinase Kinase 6', 'Mice', 'Mitogen-Activat...
10,585,441
[['A11.251.210.100', 'A11.329.228.100'], ['A11.329.114'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['G04.146.954.035'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['G04.152'], ['G05.308.320.200'], ['A11.329.228'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.30...
['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Genetic divergence between freshwater and marine morphs of alewife (Alosa pseudoharengus): a 'next-generation' sequencing analysis.
Alewife Alosa pseudoharengus, a small clupeid fish native to Atlantic Ocean, has recently (?150 years ago) invaded the North American Great Lakes and despite challenges of freshwater environment its populations exploded and disrupted local food web structures. This range expansion has been accompanied by dramatic chang...
['Animals', 'Atlantic Ocean', 'Base Sequence', 'Evolution, Molecular', 'Female', 'Fishes', 'Genetic Variation', 'Lakes', 'Molecular Sequence Data', 'Polymorphism, Single Nucleotide', 'RNA, Ribosomal, 16S', 'Sequence Analysis, RNA', 'Sequence Homology, Nucleic Acid', 'Transcriptome', 'United States']
22,438,868
[['B01.050'], ['Z01.756.092'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045.250', 'G16.075.250'], ['B01.050.150.900.493'], ['G05.365'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['L01.453.245.667'], ['G05.365.795.598'], ['D13.444.735.686.670'], ['E05.393.760.710'], ['G02.111.810...
['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
1
1
0
1
0
0
0
1
0
1
1
Population pharmacokinetics of orally administered paclitaxel formulated in Cremophor EL.
AIM: The vehicle Cremophor EL (CrEL) has been shown to impair the absorption of paclitaxel by micellar entrapment of the drug in the gastrointestinal tract. The goal of this study was to develop a semimechanistic population pharmacokinetic model to study the influence of CrEL on the oral absorption of paclitaxel.METHOD...
['Absorption', 'Adult', 'Aged', 'Antineoplastic Agents, Phytogenic', 'Biological Availability', 'Dose-Response Relationship, Drug', 'Glycerol', 'Humans', 'Middle Aged', 'Paclitaxel', 'Pharmaceutical Vehicles', 'Surface-Active Agents']
15,752,379
[['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248.179'], ['G03.787.151', 'G07.690.725.129'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.800.875.500', 'D09.853.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'...
['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
1
1
0
1
0
0
0
0
1
0
0
Systemic transthyretin amyloidosis in a patient with bent spine syndrome.
Wild-type and mutant transthyretin (TTR) are implicated in systemic amyloidosis (ATTR). Myopathy is a rare complication of ATTR amyloidosis, however no patient with bent spine syndrome secondary to ATTR amyloidosis has been reported so far. We present the first case of bent spine syndrome in a patient with wild-type AT...
['Aged', 'Alzheimer Disease', 'Amyloid Neuropathies, Familial', 'Humans', 'Male', 'Muscular Diseases', 'Prognosis', 'Spinal Curvatures']
23,638,719
[['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['C10.574.500.050', 'C10.668.829.050.050', 'C16.320.400.050', 'C16.320.565.176.050', 'C18.452.648.176.050', 'C18.452.845.500.050.050', 'C18.452.845.500.075.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.651', 'C10.668.49...
['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
1
0
0
0
0
0
1
0
0
Postmortem evaluation of cholesterol, triglyceride, and apolipoprotein levels.
Cholesterol and triglyceride levels have been analyzed in the forensic setting and their values correlated with atherosclerotic lesions found at autopsy and histology. Nevertheless, the results of these investigations have provided diverging information on postmortem molecule stability and postmortem measurement reliab...
['Adult', 'Aged', 'Apolipoprotein A-I', 'Apolipoprotein B-100', 'Cholesterol', 'Coronary Artery Disease', 'Female', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Pericardial Fluid', 'Postmortem Changes', 'Triglycerides']
28,821,961
[['M01.060.116'], ['M01.060.116.100'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['D10.532.091.300.249', 'D12.776.070.400.300.249', 'D12.776.521.120.300.249'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C14.280.647.250.260', 'C14.907.137.126.339', '...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
0
0
0
0
0
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1
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Normal fetal lumbar spine on postmortem MR imaging.
BACKGROUND AND PURPOSE: There is an increasing interest in use of postmortem MR imaging as an adjunct or alternative to autopsy. Before evaluating spinal pathology on postmortem MR imaging, it is important to have knowledge of the normal appearance of the fetal spine at different gestational ages. The aim of this study...
['Autopsy', 'Fetus', 'Gestational Age', 'Humans', 'Lumbar Vertebrae', 'Magnetic Resonance Imaging', 'Reference Values']
16,551,992
[['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['E01.370.350.825.500'], ['E05.978.810']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]']
1
1
0
0
1
0
1
0
1
0
0
0
0
0
Experimental infection of ticks Ixodes ricinus with tick-borne encephalitis virus under different microclimatic conditions.
The influence of environmental temperature and relative air humidity on the development of ticks Ixodes ricinus and their infection rate with tick-borne encephalitis virus was studied. It was found that the temperature influenced significantly the development of ticks, but it did not influence their infection rate. To ...
['Animals', 'Arachnid Vectors', 'Encephalitis Viruses, Tick-Borne', 'Encephalitis, Tick-Borne', 'Humidity', 'Mice', 'Temperature', 'Ticks', 'Viremia']
2,227,716
[['B01.050'], ['N06.850.335.188.100.100', 'N06.850.520.203.375.100.100'], ['B04.820.230.511', 'B04.820.578.344.350.350'], ['C01.207.245.340.300.775', 'C01.207.399.750.300.775', 'C01.920.500.343.360', 'C01.920.930.400', 'C01.925.081.343.360', 'C01.925.182.525.300.350', 'C01.925.782.310.360', 'C01.925.782.350.250.500', '...
['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]']
0
1
1
0
0
0
1
0
0
0
0
0
1
0
Reproducibility of contrast-enhanced transrectal ultrasound of the prostate.
Transrectal three-dimensional (3-D) contrast-enhanced power Doppler ultrasound (US) is a novel technique for studying possible prostate malignancy. Before studies can be performed to investigate the clinical validity of the technique, reproducibility of the contrast US studies must be proven. Reproducibility of contras...
['Aged', 'Contrast Media', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Middle Aged', 'Prostate', 'Prostatic Neoplasms', 'Reproducibility of Results', 'Ultrasonography, Doppler', 'Ultrasonography, Interventional']
11,397,523
[['M01.060.116.100'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.116.630'], ['A05.360.444.575', 'A10.336.707'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E05.318.370.725', 'E05.337.851',...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]']
1
1
1
1
1
0
0
0
0
0
1
1
1
0
Post-transcriptional regulation of interleukin 1 alpha in various strains of young and senescent human umbilical vein endothelial cells.
Human umbilical vein endothelial cell (HUVEC) senescence in vitro is characterized by the loss of proliferative potential and an increase in cell size. Because HUVEC senescence in one strain (H101) has been characterized by the increase in the steady-state mRNA level for the signal-peptideless cytokine, interleukin (IL...
['Base Sequence', 'Cell Division', 'Cell Size', 'Cellular Senescence', 'Endothelium, Vascular', 'Gene Expression Regulation', 'Humans', 'Interleukin-1', 'Molecular Sequence Data', 'RNA Processing, Post-Transcriptional', 'RNA, Messenger', 'Umbilical Veins']
8,108,444
[['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.325'], ['G04.043'], ['A07.015.700.500', 'A10.272.491.355'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D1...
['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]']
1
1
0
1
0
0
1
0
0
0
1
0
0
0
Increased heat loss in ovariectomized hypothyroid rats treated with estradiol.
The role of the thyroid in the mediation of an estrogen-associated change in thermal balance was studied in thyroidectomized and in propylthiouracil-treated ovariectomized rats. Prior to propylthiouracil treatment, estrogen-treated ovariectomized rats and intact female rats had higher rates of heat production and dry h...
['Animals', 'Castration', 'Estradiol', 'Female', 'Hypothyroidism', 'Kinetics', 'Propylthiouracil', 'Rats', 'Rats, Inbred Strains', 'Water Loss, Insensible']
7,091,398
[['B01.050'], ['E04.270.282', 'E04.950.165'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['C19.874.482'], ['G01.374.661', 'G02.111.490'], ['D03.383.742.698.875.842.708'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G02.111.635.5...
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
0
0
0
0
0
0
0
The role of divalent cations in structure and function of murine adenosine deaminase.
For murine adenosine deaminase, we have determined that a single zinc or cobalt cofactor bound in a high affinity site is required for catalytic function while metal ions bound at an additional site(s) inhibit the enzyme. A catalytically inactive apoenzyme of murine adenosine deaminase was produced by dialysis in the p...
['Adenosine Deaminase', 'Animals', 'Apoenzymes', 'Cations, Divalent', 'Chelating Agents', 'Circular Dichroism', 'Cloning, Molecular', 'Cobalt', 'Escherichia coli', 'Kinetics', 'Mice', 'Protein Conformation', 'Recombinant Proteins', 'Zinc']
9,144,774
[['D08.811.277.151.486.075'], ['B01.050'], ['D08.811.255.500', 'D12.776.070.290'], ['D01.248.497.300.333'], ['D27.505.519.914.500', 'D27.720.832.500'], ['E05.196.867.151'], ['E05.393.220'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661',...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
Immunohistochemical expressions of fatty acid synthase and phosphorylated c-Met in thyroid carcinomas of follicular origin.
Thyroid carcinoma is the most common endocrine malignancy and the first cause of death among endocrine cancers. Fatty acid synthase (FASN) and c-Met are overexpressed in many types of human cancers. Recent studies have suggested a functional interaction between FASN and c-Met. However, their roles in thyroid carcinomas...
['Adenocarcinoma, Follicular', 'Biomarkers, Tumor', 'Fatty Acid Synthases', 'Humans', 'Immunohistochemistry', 'Phosphorylation', 'Proto-Oncogene Proteins c-met', 'Thyroid Neoplasms']
22,135,723
[['C04.557.470.200.025.060'], ['D23.101.140'], ['D08.811.277.352.897.387', 'D08.811.520.241.300.287', 'D08.811.682.047.820.196.500', 'D08.811.913.050.134.029.500', 'D08.811.913.050.170.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', '...
['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
1
0
0
0
0
0
0
Use of phenotypic and genotypic fingerprinting methods in the strain identification of Aspergillus fumigatus.
Aspergillus fumigatus isolates (n = 6) from a lung transplant recipient, one isolate from a patient who had been on the same ward and a reference strain (NCPF 2140) were compared using three typing methods: SDS-PAGE, immunoblotting with serum from the transplant patient and random amplified polymorphic DNA (RAPD) assay...
['Aspergillus fumigatus', 'Base Sequence', 'DNA Fingerprinting', 'DNA Primers', 'Electrophoresis, Polyacrylamide Gel', 'Genotype', 'Humans', 'Lung', 'Lung Transplantation', 'Molecular Sequence Data', 'Phenotype', 'Random Amplified Polymorphic DNA Technique']
8,720,191
[['B01.300.381.081.295'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.380'], ['B01.050.150.900.649.313.988.40...
['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]']
1
1
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