Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Relationship between velopharyngeal dimensions and palatal EMG during progressive hypercapnia. | To examine the contribution of specific palatal muscles to velopharyngeal dimensions, we recorded electromyographic (EMG) activity in the levator veli palatini, the tensor veli palatini, and the palatoglossus while examining the velopharynx (VP) with videoendoscopy in eight awake normal adults. Simultaneous display of ... | ['Adult', 'Carbon Dioxide', 'Electromyography', 'Humans', 'Hypercapnia', 'Laryngoscopy', 'Palatal Muscles', 'Palate, Soft', 'Pharynx', 'Respiratory Mechanics', 'Videotape Recording'] | 8,929,587 | [['M01.060.116'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['A02.633.567.750', 'A14.549.617.623'], ['A14.549.617.780'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
B*07:156, revealed by sequence-based typing of a leukemia patient and confirmed by allele-specific amplification. | We present the full-length sequence of the novel allele HLA-B*07:156, closely related to B*07:02:01. | ['Alleles', 'HLA-B7 Antigen', 'Humans', 'Leukemia', 'Molecular Sequence Data'] | 23,163,865 | [['G05.360.340.024.340.030'], ['D12.776.395.550.489.500.070', 'D12.776.543.550.439.500.070', 'D23.050.301.500.100.500.070', 'D23.050.301.500.450.380.070', 'D23.050.705.552.100.500.070', 'D23.050.705.552.450.380.070'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['L01.453.245.667']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of connective tissue growth factor on human renal tubular epithelial cell transdifferentiation. | To investigate the role of connective tissue growth factor (CTGF) in transdifferentiation of human renal tubular epithelial cell (HKC), in vitro cultured HKC cells were divided into 3 groups: negtive control, low dose CTGF-treated group (rh CTGF, 2.5 ng/ml) and high dose CTGF-treated (rhCTGF, 5.0 ng/ml). Then the expre... | ['Actins', 'Cell Differentiation', 'Cells, Cultured', 'Connective Tissue Growth Factor', 'Epithelial Cells', 'Humans', 'Immediate-Early Proteins', 'Insulin-Like Growth Factor Binding Proteins', 'Intercellular Signaling Peptides and Proteins', 'Kidney Tubules'] | 15,587,396 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G04.152'], ['A11.251'], ['D12.644.276.200.100', 'D12.776.467.200.100', 'D12.776.860.300.200.100', 'D23.529.237.100'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.460', 'D12.776.964.925.968'], ['D12.776.157.420'], ['D12... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glycoalkaloids as biomarkers for recognition of cultivated, wild, and somatic hybrids of potato. | Cultivated and wild potato species synthesize a wide variety of steroidal glycoalkaloids (GAs). During breeding programs, species genomes are often put together through either sexual or somatic hybridization. Therefore, the determination of the GA composition of hybrids is very important in that it may affect either hu... | ['Alkaloids', 'Biomarkers', 'Chromatography, High Pressure Liquid', 'Hybridization, Genetic', 'Plant Tubers', 'Solanine', 'Solanum tuberosum'] | 19,353,547 | [['D03.132'], ['D23.101'], ['E05.196.181.400.300'], ['E05.820.150.390', 'G05.090.390'], ['A18.400.625'], ['D03.132.760.769', 'D04.210.500.247.515.500.500', 'D04.210.500.247.808.874', 'D09.408.782.674', 'D10.570.938.897'], ['B01.650.940.800.575.912.250.908.500.725.777']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Results of the treatment of ocular toxoplasmosis in personal experience]. | Ocular toxoplasmosis manifested itself in following clinical forms: as central serous chorioretinitis, pars planitis, iritis, intrabulbar neuritis and central retinal degeneration. The diagnosis was based on the clinical picture, serological examinations, the course of the disease and the effect of the specific treatme... | ['Adult', 'Aged', 'Antiprotozoal Agents', 'Chorioretinitis', 'Humans', 'Iritis', 'Light Coagulation', 'Macular Degeneration', 'Middle Aged', 'Optic Neuritis', 'Recurrence', 'Toxoplasmosis, Ocular', 'Treatment Outcome'] | 1,640,683 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.250.100'], ['C11.768.773.348', 'C11.941.160.478.400', 'C11.941.879.780.900.300.318'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.941.375.385', 'C11.941.879.780.880.448'], ['E02.520.745', 'E04.350.750', 'E04.540.630'], ['C11.768.585.439'], ['M01.060.11... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Report of a Novel Case of Anaplastic Olfactory Groove Meningioma and Its Methylation Subtype. | We report a novel case of a World Health Organization grade 3 anaplastic meningioma arising from the olfactory groove in an 83-year-old woman. Molecular and methylation profiling confirm this lesion to be an NF2 subtype, methylation class intermediate type B meningioma. As most meningiomas in this location are indolent... | ['Aged, 80 and over', 'DNA Methylation', 'Female', 'Humans', 'Meningeal Neoplasms', 'Meningioma'] | 29,045,680 | [['M01.060.116.100.080'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.557.580.520', 'C04.557.645.520', 'C04.588.614.250.580.500', 'C10.551.240.500.500']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of phencyclidine (PCP)-like drugs on turning behavior, 3H-dopamine uptake, and 3H-PCP binding. | In this study representatives from three chemical classes which are known to produce a phencyclidine (PCP)-like discriminative stimulus cue in rats were tested for their ability to inhibit synaptosomal uptake of 3H-dopamine (3H-DA) and to compete for a binding site labeled with 3H-PCP. Although there was a good correla... | ['Animals', 'Benzomorphans', 'Binding, Competitive', 'Dioxolanes', 'Dioxoles', 'Dopamine', 'Male', 'Morphinans', 'Motor Activity', 'Phencyclidine', 'Rats', 'Rats, Inbred Strains', 'Receptors, Neurotransmitter', 'Receptors, Phencyclidine', 'Synaptosomes'] | 2,989,942 | [['B01.050'], ['D03.132.577.249.106', 'D04.615.723.795.106'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D03.383.246.238'], ['D03.383.246'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D03.132.577.249', 'D03.605.497', 'D03.633.400.686', 'D04.615.723.795'], ['F01.14... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of antimicrobial resistance among respiratory tract isolates of Streptococcus pneumoniae in North America: 1997 results from the SENTRY antimicrobial surveillance program. | As part of the ongoing multinational SENTRY antimicrobial resistance surveillance program, a total of 1,047 respiratory tract isolates of Streptococcus pneumoniae, 845 from 27 United States medical centers and 202 from seven Canadian institutions, were collected between February and June 1997 and characterized in a cen... | ['Drug Resistance, Microbial', 'Humans', 'Microbial Sensitivity Tests', 'North America', 'Prevalence', 'Respiratory System', 'Streptococcus pneumoniae'] | 9,798,031 | [['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['Z01.107.567'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['A04'], ['B03.353.750.737.872.550', 'B0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Virological diagnosis in community-acquired pneumonia in immunocompromised patients. | Community-acquired pneumonia (CAP) is a serious lower respiratory tract infection associated with significant morbidity and mortality in immunocompromised patients. The present study evaluated the clinical spectrum of CAP in immunocompromised hosts and the role of respiratory viruses, as well as the yield of viral diag... | ['Adult', 'Aged', 'Community-Acquired Infections', 'Female', 'Humans', 'Immunocompromised Host', 'Male', 'Middle Aged', 'Nasopharynx', 'Pneumonia, Pneumococcal', 'Pneumonia, Viral', 'Polymerase Chain Reaction', 'Prospective Studies', 'Spain'] | 17,959,637 | [['M01.060.116'], ['M01.060.116.100'], ['C01.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'], ['M01.060.116.630'], ['A04.623.557', 'A14.724.557'], ['C01.150.252.410.890.670.750', 'C01.150.252.620.550', 'C01.748.610.540.550', 'C08.381.677.540.550', 'C08.730.610.540.550'], ['C01.748.610.763', 'C01.925... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Decrease of gastrointestinal mucosal damage by salicyluric acid compared with salicylic acid in rabbits. | The gastrointestinal mucosal damage following the oral administration of salicylic acid or salicyluric acid was examined in rabbits using a scanning electron microscope. Six and 24 h after treatment with salicylic acid, morphological changes of gastric mucosa were recognized. In rabbits treated with salicyluric acid, h... | ['Administration, Oral', 'Animals', 'Gastric Mucosa', 'Gastrointestinal Diseases', 'Hippurates', 'Intestinal Mucosa', 'Male', 'Microscopy, Electron, Scanning', 'Rabbits', 'Salicylates', 'Salicylic Acid'] | 1,686,904 | [['E02.319.267.100'], ['B01.050'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C06.405'], ['D02.065.277.431', 'D02.241.223.100.100.400', 'D02.241.755.360', 'D02.455.426.559.389.127.085.460'], ['A03.556.124.369', 'A10.615.550.444'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B01.050.150.900.649.313.968.700'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer. | Definitive radiotherapy improves locoregional control and survival in inoperable non-small cell lung cancer patients. However, radiation-induced toxicities (pneumonitis/esophagitis) are common dose-limiting inflammatory conditions. We therefore conducted a pathway-based analysis to identify inflammation-related single-... | ['Aged', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Genetic Variation', 'Humans', 'Inflammation', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Radiation Tolerance', 'Radiotherapy'] | 25,054,431 | [['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['G05.365.795.598'], ['G04.712', 'G07.738'], ['E02.815']... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Design of supported membranes tethered via metal-affinity ligand-receptor pairs. | Model lipid layers are very promising in investigating the complex network of recognition, transport and signaling processes at membranes. We have developed a novel and generic approach to create supported lipid membranes tethered by metal-affinity binding. By self-assembly we have generated various interfaces that dis... | ['Affinity Labels', 'Amino Acid Sequence', 'Chelating Agents', 'Drug Design', 'Histidine', 'Ligands', 'Lipid Bilayers', 'Metals', 'Models, Molecular', 'Molecular Sequence Data', 'Peptides', 'Receptors, Cell Surface', 'Sulfhydryl Compounds'] | 11,106,619 | [['D27.720.470.410.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.519.914.500', 'D27.720.832.500'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D12.125.072.329', 'D12.125.142.308'], ['D27.720.470.480'], ['D10.570.510', 'J01.637.087.500.510'], ['D01.552'], ['E05.599.595'], ['L01.45... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Surveillance of sylvatic plaque in Oregon by serotesting carnivores. | In Oregon, during 1974-1979, 10.3 per cent of 3.255 statewide blood samples from carnivores were positive for Yersinia pestis. The per cent positive rate and geometric mean positive titer increase monthly from January (6.5 per cent) to June (21.7 per cent), and decline thereafter. Data are presented on how geographic l... | ['Animals', 'Carnivora', 'Humans', 'Oregon', 'Plague', 'Seasons', 'Time Factors', 'Yersinia pestis'] | 7,125,037 | [['B01.050'], ['B01.050.150.900.649.313.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.560.550', 'Z01.107.567.875.580.550'], ['C01.150.252.400.310.980.390', 'C01.920.906'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.910.857'], ['B03.440.450.425.900.600', 'B03... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Magnifying colonoscopy in differentiating neoplastic from nonneoplastic colorectal lesions. | OBJECTIVE: Because the medical management of persons with adenomatous colorectal polyps differs from that of those with hyperplastic polyps, accuracy of diagnosis is essential. This study reports our experience using a magnifying colonoscope combined with indigocarmine dye to diagnose colorectal polyps, emphasizing its... | ['Adult', 'Aged', 'Aged, 80 and over', 'Colonic Polyps', 'Colonoscopy', 'Colorectal Neoplasms', 'Diagnosis, Differential', 'Female', 'Humans', 'Indigo Carmine', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Reproducibility of Results'] | 11,569,686 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.825.411.235'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multiple independent second-site mutations in two siblings with somatic mosaicism for Wiskott-Aldrich syndrome. | Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency disorder associated with microthrombocytopenia, eczema, autoimmunity and predisposition to malignant lymphoma. Although rare, few cases of somatic mosaicism have been published in WAS patients to date. We here report on two Ukrainian siblings who we... | ['Child, Preschool', 'Codon, Nonsense', 'Humans', 'Male', 'Mosaicism', 'Siblings', 'Wiskott-Aldrich Syndrome', 'Wiskott-Aldrich Syndrome Protein'] | 18,479,478 | [['M01.060.406.448'], ['D13.444.735.544.355.250.235', 'G05.360.335.355.250.235', 'G05.365.590.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.175.595'], ['F01.829.263.500.490', 'I01.880.853.150.500.505', 'M01.781'], ['C15.378.100.100.970', 'C15.378.463.960', 'C15.378.553.546.605.900', 'C16.320.099... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Cutaneous parasitism by Leishmania (Leishmania) chagasi during South American visceral leishmaniasis]. | Eighteen patients from the northeastern Brazilian State of Ceara with proven kala-azar were studied for evidence of skin parasitism: two had ulcerative or papular skin lesions and 16 had clinically normal skin. Punch biopsies (3 mm) of intact paraspinal subscapular skin were performed on all patients; in those with pap... | ['Adolescent', 'Adult', 'Animals', 'Brazil', 'Child', 'Child, Preschool', 'Humans', 'Leishmania donovani', 'Leishmaniasis, Visceral', 'Male', 'Skin'] | 8,353,466 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.268.475.868.488.230'], ['C01.610.752.300.500.510', 'C01.920.813.510'], ['A17.815']] | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
L-lysine pro-prodrug containing trans-ferulic acid for 5-amino salicylic acid colon delivery: synthesis, characterization and in vitro antioxidant activity evaluation. | In the present work, we report the synthesis of a new 5-amino salicylic acid (5-ASA) pro-prodrug, useful in Crohn disease treatment, and the evaluation of its antioxidant activity. Using as pharmacological carrier L-lysine amino acid and taking advantage of its intrinsic chemical reactivity, due to the presence of two ... | ['Animals', 'Antioxidants', 'Colon', 'Coumaric Acids', 'Lipid Peroxidation', 'Lysine', 'Mesalamine', 'Microsomes, Liver', 'Prodrugs', 'Rats'] | 20,045,975 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['D02.241.223.200.210'], ['G02.111.515', 'G03.295.531.587'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['D02.241.223.100.050.300.500', 'D02.241.223.100.300.595.100.540', 'D02.241... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha. | Accumulating evidence has suggested that cellular production of superoxide acts as an intracellular messenger to regulate gene expression and modulate cellular activities. In this report, we set out to investigate the role of active H-ras-mediated superoxide production on tumor cell malignancy in a SV-40 transformed hu... | ['Acetophenones', 'Allopurinol', 'Cell Division', 'Cell Line, Transformed', 'Cell Movement', 'Drug Resistance', 'Enzyme Activation', 'Genes, ras', 'Genistein', 'Humans', 'Lung Neoplasms', 'Membrane Proteins', 'Models, Biological', 'NADPH Oxidases', 'Onium Compounds', 'Oxypurinol', 'Protein Kinase Inhibitors', 'Rotenone... | 11,313,892 | [['D02.522.120'], ['D03.633.100.759.160'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210.172'], ['G04.198', 'G07.568.500.180'], ['G07.690.773.984'], ['G02.111.263', 'G03.328'], ['G05.360.340.024.340.375.500.791.550'], ['D03.383.663.283.266.450.400.375', 'D03.633.100.150.266.450... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial. | CONTEXT: The Women's Health Initiative (WHI) trial of estrogen plus progestin was stopped early because of adverse effects, including an increased risk of stroke in the estrogen plus progestin group.OBJECTIVE: To assess the effect of estrogen plus progestin on ischemic and hemorrhagic stroke and in subgroups, and to de... | ['Aged', 'Biomarkers', 'Double-Blind Method', 'Estrogen Replacement Therapy', 'Estrogens, Conjugated (USP)', 'Female', 'Humans', 'Medroxyprogesterone Acetate', 'Middle Aged', 'Postmenopause', 'Progesterone Congeners', 'Proportional Hazards Models', 'Risk Factors', 'Stroke', 'Survival Analysis'] | 12,771,114 | [['M01.060.116.100'], ['D23.101'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.452.150'], ['D06.472.334.851.437.988'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.829.395.700.500'], ['M01.060.116.630'], ['G08.686.157.500.625', 'G08.686.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The reliability and repeatability of the blood glucose response to prolonged exercise in adolescent boys with IDDM. | OBJECTIVE: To determine the intrasubject reliability and repeatability of the blood glucose response to prolonged exercise in adolescents with insulin-dependent diabetes mellitus (IDDM) when pre-exercise meal, exercise, and insulin regimens are kept constant.RESEARCH DESIGN AND METHODS: Nine IDDM adolescent boys with d... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Blood Glucose', 'Diabetes Mellitus, Type 1', 'Drug Administration Schedule', 'Eating', 'Exercise', 'Exercise Test', 'Heart Rate', 'Humans', 'Hypoglycemia', 'Insulin', 'Male', 'Perception', 'Reproducibility of Results'] | 7,555,475 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D09.947.875.359.448.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E02.319.283'], ['G07.203.650.283', 'G10.261.330'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Identification and Sequencing of N-Terminal Peptides in Proteins by LC-Fluorescence-MS/MS: An Approach to Replacement of the Edman Degradation. | Automated Edman degradation for sequencing is the classic tool for determining the N-terminal sequences of proteins. Although it has been complemented or largely replaced by a variety of mass spectrometric methods in recent years, there is no simple mass spectrometric method for identification and de novo determination... | ['Amino Acid Sequence', 'Chromatography, Liquid', 'Fluorescent Dyes', 'Peptides', 'Sequence Analysis, Protein', 'Spectrometry, Fluorescence', 'Tandem Mass Spectrometry'] | 31,573,189 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.181.400'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D12.644'], ['E05.393.760.705'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['E05.196.566.880']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Design, synthesis and antibacterial evaluation of novel AHL analogues. | Two series of novel AHL analogues were designed, synthesized and evaluated for antibacterial activity under cell membrane conditions in vitro. Analogues 4a-c and 4g-m presented potent activity against Gram-positive bacteria. Especially the analogue 4l exerted the most potent inhibition against Bacillus subtilis with MI... | ['4-Butyrolactone', 'Anti-Bacterial Agents', 'Carbamates', 'Drug Design', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Microbial Sensitivity Tests', 'Quorum Sensing'] | 23,735,742 | [['D02.540.150', 'D03.383.312.150'], ['D27.505.954.122.085'], ['D02.241.081.251'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B03.440'], ['B03.510'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G04.085.700', 'G06.550.700']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies of high thermostability and peroxidase activity of recombinant antibody L chain-porphyrin Fe(III) complex. | A complex of an independent L chain from anti-mesotetrakis (4-carboxyphenyl) porphyrin (TCPP) monoclonal antibody 13-1 and TCPP Fe(III) was designated as L-zyme and shown to exhibit high peroxidase activity and high optimal reaction temperature (90 degrees C). Heat denaturation study and circular dichroism (CD) spectra... | ['Animals', 'Antibodies, Catalytic', 'Antibodies, Monoclonal', 'Enzyme Stability', 'Escherichia coli', 'Hot Temperature', 'Immunoglobulin Light Chains', 'Iron', 'Mice', 'Models, Molecular', 'Molecular Structure', 'Peroxidases', 'Porphyrins', 'Protein Conformation', 'Protein Denaturation', 'Recombinant Proteins', 'Seque... | 9,175,868 | [['B01.050'], ['D12.776.124.486.485.114.167', 'D12.776.124.790.651.114.167', 'D12.776.377.715.548.114.167'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.906.595.543', 'G16... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
How should patients consult? A study of the differences in viewpoint between doctors and patients. | BACKGROUND: Increasing pressure on limited NHS resources has led to the introduction in primary care of a skill mix which seeks to match clinical presentation to an intervention based on skills and training. There has also been increasing emphasis on the use of telephone consultations. However, outcomes on the benefits... | ['Attitude of Health Personnel', 'Data Collection', 'Family Practice', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Nursing Care', 'Patient Compliance', 'Patient Satisfaction', "Physician's Role", 'Referral and Consultation', 'Sensitivity and Specificity', 'Surveys and Questionnaires', 'United ... | 10,625,127 | [['F01.100.050', 'N05.300.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['H02.403.340.500'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.611', 'N02.421.533'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
High birthweight in an ethnic group of low socioeconomic status. | Analysis of 14 219 births in West Jerusalem showed that infants of North African origin had a higher birthweight than infants of other ethnic groups. The group of mothers of North African origin included a relatively high proportion from the lowest social classes. The observed excess birthweight was apparent after allo... | ['Africa, Northern', 'Birth Weight', 'Emigration and Immigration', 'Female', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Israel', 'Male', 'Maternal Age', 'Parity', 'Pregnancy', 'Socioeconomic Factors'] | 6,838,787 | [['Z01.058.266'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A randomized trial of 5 versus 7 French guiding catheters for transfemoral percutaneous coronary stent implantation. | Comparative studies between 5 French guiding catheter and others of larger size using the transfemoral approach to coronary stenting have not been described. Coronary stent implantation was performed in 90 patients in a randomized trial. The primary end-point was to compare the incidence of successful uncomplicated ste... | ['Angioplasty, Balloon, Coronary', 'Cardiac Catheterization', 'Coronary Angiography', 'Female', 'Femoral Artery', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prospective Studies', 'Stents'] | 18,093,100 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.37... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of cocaine and nicotine on amino acid transport across the human placental cotyledon perfused in vitro. | The inhibitory effects of cocaine and nicotine on placental amino acid transport, as a mechanism contributing to intrauterine growth restriction, were investigated in the in vitro placental perfusion model. Amino acids that represent substrates for known placental transporters were selected: alanine (system A), glutami... | ['Amino Acids', 'Biological Transport', 'Cocaine', 'Female', 'Humans', 'Nicotine', 'Perfusion', 'Placenta', 'Pregnancy'] | 10,871,305 | [['D12.125'], ['G03.143'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.760.570', 'D03.383.725.518'], ['E05.680'], ['A16.710'], ['G08.686.784.769']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient auto-excision of a selectable marker gene from transgenic citrus by combining the Cre/loxP system and ipt selection. | KEY MESSAGE: A highly efficient Cre-mediated deletion system, offering a good alternative for producing marker-free transgenic plants that will relieve public concerns regarding GMOs, was first developed in citrus. The presence of marker genes in genetically modified crops raises public concerns regarding their safety.... | ['Agrobacterium tumefaciens', 'Alkyl and Aryl Transferases', 'Base Sequence', 'Citrus', 'DNA, Bacterial', 'Gene Deletion', 'Gene Expression Regulation, Plant', 'Genes, Reporter', 'Genetic Vectors', 'Green Fluorescent Proteins', 'Integrases', 'Molecular Sequence Data', 'Plants, Genetically Modified', 'Recombination, Gen... | 23,771,575 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['D08.811.913.225'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.650.940.800.575.912.250.875.177'], ['D13.444.308.212'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308.375'], ['G05.360.340.024.340.435'], ['G05.360.337'], ['D12.776.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Shape abnormalities of caudate nucleus in schizotypal personality disorder. | BACKGROUND: Previously, we reported abnormal volume and global shape in the caudate nucleus in schizotypal personality disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures.METHODS: Thirty-two female ... | ['Adult', 'Brain Mapping', 'Caudate Nucleus', 'Female', 'Functional Laterality', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Models, Neurological', 'Neuropsychological Tests', 'Schizotypal Personality Disorder', 'Sex Factors', 'Statistics as Topic', 'Young Adul... | 19,328,654 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.249.487.550.184'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.599.395.642'], ['F04.711... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Multiple and recurrent inflammatory fibroid polyps in a Devon family ('Devon polyposis syndrome'): an update. | Inflammatory fibroid polyps are uncommon but well documented as solitary polyps occurring typically in the stomach or ileum. A Devon family has previously been reported in which a female in three successive generations has presented with multiple polyps requiring repeated surgery over a number of years. A further two f... | ['Adult', 'Female', 'Gastrointestinal Neoplasms', 'Humans', 'Ileal Neoplasms', 'Neoplasms, Second Primary', 'Pedigree', 'Polyps', 'Stomach Neoplasms', 'Syndrome'] | 1,644,320 | [['M01.060.116'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411.501', 'C06.301.371.411.501', 'C06.405.249.411.501', 'C06.405.469.420.501', 'C06.405.469.491.501'], ['C04.692'], ['E05.393.673'], ['C23.300.825'], ['C04.588.274.476.767', 'C06.301.3... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of opioid use and prescribing patterns in orthopedic surgery in Japan and the United States: A JOA-AOA Traveling Fellowship Investigation. | BACKGROUND: The US continues to be in the midst of an opioid epidemic. The prescription of narcotics for acute injury or post-operative pain is a common inciting event leading to opioid abuse and addiction. It is eminently important for orthopedic surgeons to lead the charge in changing practice patterns to decrease th... | ['Adult', 'Aged', 'Aged, 80 and over', 'Analgesics, Opioid', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Orthopedic Surgeons', 'Pain, Postoperative', "Practice Patterns, Physicians'", 'Surveys and Questionnaires', 'United States'] | 31,155,440 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['M01.526.485.810.910.87... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Single chamber microbial fuel cell (SCMFC) with a cathodic microalgal biofilm: A preliminary assessment of the generation of bioelectricity and biodegradation of real dye textile wastewater. | An air exposed single-chamber microbial fuel cell (SCMFC) using microalgal biocathodes was designed. The reactors were tested for the simultaneous biodegradation of real dye textile wastewater (RTW) and the generation of bioelectricity. The results of digital image processing revealed a maximum coverage area on the bio... | ['Biodegradation, Environmental', 'Bioelectric Energy Sources', 'Biofilms', 'Coloring Agents', 'Electricity', 'Electrochemical Techniques', 'Electrodes', 'Microalgae', 'Textiles', 'Waste Water', 'Water Pollutants, Chemical'] | 28,278,426 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.305.124.150'], ['A20.593', 'G06.120'], ['D27.720.233'], ['G01.358.500.249'], ['E05.301'], ['E07.305.250'], ['B05.080.500.600.500'], ['J01.637.836'], ['D20.944.932', 'N06.850.460.710.865'], ['D27.888.284.903.655']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Location of posterior superior alveolar artery and evaluation of maxillary sinus anatomy with computerized tomography: a clinical study. | OBJECTIVES: Knowledge and evaluation of the maxillary sinus anatomy before sinus augmentation are essential for avoiding surgical complications. Posterior superior alveolar artery (PSAA) is the branch of maxillary artery that supplies lateral sinus wall and overlying membrane. The aims of this study were to examine the... | ['Alveolar Process', 'Alveolar Ridge Augmentation', 'Dental Implantation, Endosseous', 'Female', 'Humans', 'Male', 'Maxillary Artery', 'Maxillary Sinus', 'Middle Aged', 'Tomography, X-Ray Computed'] | 21,244,499 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['E04.545.550.100', 'E06.645.550.100'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.523'], ['A04.531.621.578'], ['M01.060.116.630'], ['E01.370.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
VIP activates primordial follicles of rat through ERK-mTOR pathway in tissue culture. | In vitro activation of primordial follicles is becoming more essential in assisted reproductive technologies. Vasoactive intestinal peptide (VIP) is one of the members of the neurotrophin family which has demonstrated to have an impact on follicle development in recent years. This study aims to investigate the effect o... | ['Animals', 'Animals, Newborn', 'Cells, Cultured', 'Female', 'MAP Kinase Signaling System', 'Oogenesis', 'Ovarian Follicle', 'Ovary', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Vasoactive Intestinal Peptide', 'Signal Transduction', 'TOR Serine-Threonine Kinases', 'Tissue Culture Techniques', 'Vasoactive Intestinal Pep... | 30,817,320 | [['B01.050'], ['B01.050.050.282'], ['A11.251'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['G04.152.650.249', 'G08.686.784.310.500'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The undescended "parathymus". An occasional cause of failed neck exploration for hyperparathyroidism. | Arrested descent of the inferior parathyroid gland ("parathymus") during embryologic development may leave the gland stranded high in the neck. Adenomas of such undescended glands are a rare cause of primary hyperparathyroidism, but they may not be uncommon among patients who have already had a failed cervical explorat... | ['Adenoma', 'Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Hypercalcemia', 'Hyperparathyroidism', 'Kidney Calculi', 'Male', 'Middle Aged', 'Nephrocalcinosis', 'Parathyroid Glands', 'Parathyroid Neoplasms', 'Thymus Gland'] | 464,681 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF NEOVASCULAR MACULAR TELANGIECTASIA TYPE 2. | BACKGROUND/PURPOSE: To image subretinal neovascularization in proliferative macular telangiectasia Type 2 (MacTel2) using swept source optical coherence tomography based microangiography (OMAG).METHODS: Patients with macular telangiectasia Type 2 were enrolled in a prospective, observational study known as the MacTel P... | ['Choroid', 'Coloring Agents', 'Female', 'Fluorescein Angiography', 'Humans', 'Indocyanine Green', 'Male', 'Middle Aged', 'Prospective Studies', 'Retinal Neovascularization', 'Retinal Telangiectasis', 'Retinal Vessels', 'Tomography, Optical Coherence', 'Visual Acuity'] | 26,457,402 | [['A09.371.894.223'], ['D27.720.233'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C11.768.725', 'C23.550.589.500.725'], ['C11.768.7... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Construction of insertion mutants of Synechocystis sp. PCC 6803: evidence for an essential function of subunit IV of the cytochrome b6/f complex. | The gene encoding subunit IV of the cytochrome b6/f complex (petD) has been isolated from a genomic library of the unicellular cyanobacterium Synechocystis sp. PCC 6803. The coding region consists of 480 nucleotides and can code for a polypeptide with a molecular weight of 17.5 kDa. The deduced amino acid sequence show... | ['Amino Acid Sequence', 'Base Sequence', 'Cyanobacteria', 'Cytochrome b Group', 'Cytochrome b6f Complex', 'Molecular Sequence Data', 'Mutation', 'Plasmids', 'Transformation, Bacterial'] | 1,590,707 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.280', 'B03.440.475.100'], ['D08.244.187', 'D12.776.422.220.187'], ['D05.500.562.488.374', 'D08.811.600.710.374', 'D12.776.543.585.450.250.875.311', 'D12.776.543.930.500.374', 'D12.776.765.199.750.750.374'], ['L... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
"What I Did for My Loved One Is More Important than Whether We Talked About Death": A Nationwide Survey of Bereaved Family Members. | BACKGROUND: Actions in preparation for death and talks about death between advanced cancer patients and their families are considered essential to achieve a good death. However, little is known about the prevalence of such actions compared with talks and their association with bereaved families' psychological morbidity... | ['Aged', 'Attitude to Death', 'Bereavement', 'Family', 'Female', 'Hospice Care', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Neoplasms', 'Surveys and Questionnaires'] | 29,154,690 | [['M01.060.116.100'], ['F01.100.125', 'N05.300.125'], ['F01.470.142'], ['F01.829.263', 'I01.880.853.150'], ['E02.760.905.400', 'N02.421.585.905.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['C04'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.52... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Chemical Compositions, Antiobesity, and Antioxidant Effects of Proanthocyanidins from Lotus Seed Epicarp and Lotus Seed Pot. | Lotus seed epicarp (LSE) and lotus seed pot (LSP) were characterized, and a total of 5 and 7 proanthocyanidins (PAs) were identified in purified LSE and LSP extract, respectively. Purified LSE and LSP PAs significantly suppressed the body weight and weight gain of white adipose tissue (WAT) and decreased the WAT cell s... | ['Animals', 'Anti-Obesity Agents', 'Antioxidants', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Diet, High-Fat', 'Glutathione', 'Humans', 'Leptin', 'Liver', 'Lotus', 'Male', 'Mass Spectrometry', 'Mice', 'Mice, Inbred C57BL', 'Obesity', 'Plant Extracts', 'Proanthocyanidins', 'Seeds', 'Superoxide Dismutase', 'Triglycerides'] | 30,449,095 | [['B01.050'], ['D27.505.954.203'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['G07.203.650.240.267'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Induction of nitric oxide synthase activity in nucleus ambiguus motoneurons after injury to the rat recurrent laryngeal nerve. | Recent studies have implicated nitric oxide (NO) in neuronal degeneration and plasticity in the motor nervous system. In the present study, we investigated the induction of nitric oxide synthase (NOS) in the motoneurons in the nucleus ambiguus (NA) after injury to the rat recurrent laryngeal nerve (RLN) using nicotinam... | ['Animals', 'Brain Stem', 'Enzyme Induction', 'Male', 'Motor Neurons', 'NADPH Dehydrogenase', 'Nerve Degeneration', 'Nerve Endings', 'Neuronal Plasticity', 'Nitric Oxide Synthase', 'Rats', 'Rats, Sprague-Dawley', 'Recurrent Laryngeal Nerve', 'Recurrent Laryngeal Nerve Injuries'] | 11,603,800 | [['B01.050'], ['A08.186.211.132'], ['G05.308.320.200'], ['A08.675.655.500', 'A11.671.655.500'], ['D08.811.682.608.550'], ['C23.550.737'], ['A08.800.550'], ['G11.561.638'], ['D08.811.682.664.500.772'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A08.800.050.050.925.450... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Indoor mildew odour in old housing was associated with adult allergic symptoms, asthma, chronic bronchitis, vision, sleep and self-rated health: USA NHANES, 2005-2006. | A recent systematic review and meta-analysis has shown the effect of indoor mildew odour on allergic rhinitis risk, but its relation to other common chronic health outcomes in adults has not been investigated. Therefore, it was aimed to examine the relationship of indoor mildew odour and common health outcomes in adult... | ['Adult', 'Aged', 'Aged, 80 and over', 'Air Pollution, Indoor', 'Asthma', 'Bronchitis, Chronic', 'Female', 'Fungi', 'Health Surveys', 'Housing', 'Humans', 'Hypersensitivity', 'Logistic Models', 'Male', 'Middle Aged', 'Nutrition Surveys', 'Odorants', 'Self Report', 'Sleep', 'United States', 'Vision, Ocular', 'Young Adul... | 25,971,810 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N06.850.460.100.080'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C01.748.099.567', 'C08.127.446.567', 'C08.381.495.146.567', 'C08.381.495.389.500', 'C08.730.099.567'], ['B01.300'], ['E05.318.308.980.438', 'N05.715.360.30... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Motor unit firing rates of the gastrocnemii during maximal brief steady-state contractions in humans. | The human triceps surae (soleus, medial (MG) and lateral (LG) gastrocnemii) is complex and important for posture and gait. The soleus exhibits markedly lower motor unit firing rates (MUFRs; ?16Hz) during maximal voluntary isometric contraction (MVC) than other limb muscles, but this information is unknown for the MG an... | ['Action Potentials', 'Adult', 'Humans', 'Isometric Contraction', 'Male', 'Motor Neurons', 'Muscle Contraction', 'Muscle, Skeletal', 'Posture', 'Recruitment, Neurophysiological', 'Torque', 'Young Adult'] | 26,705,963 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A08.675.655.500', 'A11.671.655.500'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['G11.427.695'], ['G07.265.753.760', 'G11.561.601.760'], ['G01.374.860.500'], ['M01.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Psychometric characteristics of the General Well-Being Schedule (GWB) with African-American women. | The General Well-Being Schedule (GWB) is a brief, reliable, and valid instrument used in population studies to assess psychological well-being, although its validity with African-Americans has yet to be established. This study evaluated the reliability, validity, and factor structure of the GWB in a sample of 599 overw... | ['Adult', 'African Americans', 'Discriminant Analysis', 'Factor Analysis, Statistical', 'Female', 'Holistic Health', 'Humans', 'Middle Aged', 'Obesity', 'Psychometrics', 'Quality of Life', 'United States'] | 12,625,516 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['E02.190.321', 'K01.752.667.710', 'N01.400.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Activation status of T and NK cells in the endometrium throughout menstrual cycle and normal and abnormal early pregnancy. | Endometrial lymphocytes were studied at all stages throughout the menstrual cycle and early pregnancy by flow cytometry to examine different lymphocyte subpopulations and the expression of the T- and NK-cell activation markers. After pregnancy, CD8+CD3+ lymphocytes were decreased in the decidua. In both endometrium and... | ['Abortion, Induced', 'Abortion, Spontaneous', 'Endometrium', 'Female', 'Humans', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Menstrual Cycle', 'Pregnancy', 'Pregnancy Trimester, First', 'Pregnancy, Ectopic', 'T-Lymphocytes'] | 8,872,167 | [['E04.520.050'], ['C13.703.039', 'G08.686.784.769.496.125'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oxiracetam in the treatment of multi-infarct dementia. | 1. Initial clinical trials in approximately 200 patients with dementias of diverse etiology suggested that oxiracetam, a structural analogue of the nootropic piracetam, was of some benefit in the treatment of cognitive dysfunction. 2. Because previous studies had not specifically examined the effects of oxiracetam upon... | ['Aged', 'Aged, 80 and over', 'Dementia, Multi-Infarct', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Pyrrolidines'] | 2,781,039 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.150.477.200.199', 'C10.228.140.300.400.408', 'C10.228.140.300.775.200.200.199', 'C10.228.140.380.230.250', 'C14.907.253.092.477.200.199', 'C14.907.253.855.200.200.199', 'C23.550.513.355.250.200.199', 'C23.550.717.489.250.200.199', 'F03.615.400.350.400'], ... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reliability and correlation of mixture cell correction in methylomic and transcriptomic blood data. | OBJECTIVES: The number of DNA methylome and RNA transcriptome studies is growing, but investigators have to consider the cell type composition of tissues used. In blood samples, the data reflect the picture of a mixture of different cells. Specialized algorithms can address the cell-type heterogeneity issue. We tested ... | ['Blood', 'Cohort Studies', 'Epigenome', 'Genomics', 'Humans', 'Reproducibility of Results', 'Transcriptome'] | 32,051,015 | [['A12.207.152', 'A15.145'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G05.360.340.006'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G02.111.87... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Is aortic atherothrombotic disease detected using multidetector-row CT associated with an increased risk of early ischemic lesion recurrence after acute ischemic stroke? | BACKGROUND AND PURPOSE: Multidetector-row CT (MDCT) is emerging as a new tool for diagnosing aortic atherothrombotic disease (AAD). We elucidated whether MDCT-detected AAD is associated with an increased risk of early ischemic lesion recurrence on diffusion-weighted MRI after ischemic stroke.METHODS: A consecutive seri... | ['Aged', 'Brain Ischemia', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Follow-Up Studies', 'Humans', 'Image Processing, Computer-Assisted', 'Intracranial Thrombosis', 'Male', 'Middle Aged', 'Recurrence', 'Risk', 'Stroke', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 22,282,886 | [['M01.060.116.100'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E01.370.350.825.500.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C10.228.140.300.525.425', 'C14.907.253.566.350', 'C14.907.355.590.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Myocardial function in the working mouse heart overexpressing cardiac A1 adenosine receptors. | Adenosine, acting via A1 receptors, modulates heart rate and contractility, and provides myocardial protection during times of stress. A transgenic model of cardiac A1 overexpression was produced and it demonstrated cardiac protection from ischemia. Since A1 receptor stimulation can inhibit contractility under some con... | ['Animals', 'Cardiotonic Agents', 'Gene Expression', 'Heart', 'Hemodynamics', 'In Vitro Techniques', 'Isoproterenol', 'Mice', 'Mice, Transgenic', 'Myocardial Contraction', 'Receptors, Purinergic P1'] | 9,500,876 | [['B01.050'], ['D27.505.954.411.222', 'D27.720.799.080'], ['G05.297'], ['A07.541'], ['G09.330.380'], ['E05.481'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.389.657.166.175.649'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.63... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The long-term results of gastric bypass on indexes of sleep apnea. | STUDY OBJECTIVES: Weight loss improves obstructive sleep apnea (OSA), and clinicians regularly recommend dieting to their patients with OSA; however, many morbidly obese patients may be unable to lose weight without medical or surgical intervention. Gastric bypass surgery (GB) facilitates weight loss for morbidly obese... | ['Adult', 'Body Mass Index', 'Cohort Studies', 'Female', 'Gastric Bypass', 'Humans', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Retrospective Studies', 'Severity of Illness Index', 'Sleep Apnea, Obstructive', 'Time Factors'] | 14,555,601 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A procedure for removing high titer antibodies by extracorporeal protein-A-sepharose adsorption in hemophilia: substitution therapy and surgery in a patient with hemophilia B and antibodies. | A 37-yr-old hemophiliac with factor IX antibody in high titer required operation for a pseudotumor growing invasively into the bone in his left elbow. Exchange plasma-pheresis was not feasible, mainly because of possible stimulation of factor IX inhibitor. In addition, the patient had antibodies against tissue antigens... | ['Absorption', 'Adult', 'Antibodies', 'Blood Coagulation Tests', 'Bone Neoplasms', 'Complement System Proteins', 'Elbow Joint', 'Factor IX', 'Hemophilia B', 'Humans', 'Male', 'Plasmapheresis', 'Sepharose'] | 7,236,891 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E01.370.225.625.115', 'E05.200.625.115'], ['C04.588.149', 'C05.116.231'], ['D12.776.124.486.274'], ['A02.835.583.290'], ['D08.622.355', 'D12.776.124... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modal kinematics for multisection continuum arms. | This paper presents a novel spatial kinematic model for multisection continuum arms based on mode shape functions (MSF). Modal methods have been used in many disciplines from finite element methods to structural analysis to approximate complex and nonlinear parametric variations with simple mathematical functions. Give... | ['Animals', 'Biomimetics', 'Computer Simulation', 'Extremities', 'Models, Biological', 'Movement', 'Muscle, Skeletal', 'Octopodiformes', 'Robotics'] | 25,969,947 | [['B01.050'], ['H01.158.550.100', 'J01.897.120.100'], ['L01.224.160'], ['A01.378'], ['E05.599.395'], ['G07.568', 'G11.427.410'], ['A02.633.567', 'A10.690.552.500'], ['B01.050.500.644.116.600'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Ontogeny of opioid and related peptides in the rat cns and pituitary: an immunocytochemical study. | The development of proopiomelanocortin (POMC) derived peptides was compared to that of leucine-enkephalin ([Leu]ENK) and dynorphin A (DYN-A) immunoreactivity (i.r.) in the rat CNS and pituitary gland. POMC i.r. appeared first in hypothalamic neurons on embryonic day E12, in pituitary anterior lobe (AL) cells on E15, in... | ['Aging', 'Animals', 'Brain', 'Dynorphins', 'Embryo, Mammalian', 'Endorphins', 'Enkephalin, Leucine', 'Female', 'Peptide Fragments', 'Pituitary Gland', 'Pituitary Hormones, Anterior', 'Pregnancy', 'Pro-Opiomelanocortin', 'Protein Precursors', 'Rats', 'Rats, Inbred Strains'] | 6,141,503 | [['G07.345.124'], ['B01.050'], ['A08.186.211'], ['D12.644.400.575.180', 'D12.776.631.650.575.180'], ['A16.254'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['D12.644.400.575.281.231', 'D12.776.631.650.575.281.231'], ['D12.644.541'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Soy milk consumption and blood pressure among type 2 diabetic patients with nephropathy. | OBJECTIVE: The purpose of this study was to determine the effects of soy milk consumption cardiovascular risk and biomarkers of renal function in type 2 diabetic patients with nephropathy.METHODS: This randomized, crossover, controlled clinical trial was conducted in 29 type 2 diabetic patients with nephropathy. Partic... | ['Adult', 'Animals', 'Biomarkers', 'Blood Pressure', 'Body Mass Index', 'Cardiovascular Diseases', 'Cholesterol', 'Cross-Over Studies', 'Diabetes Mellitus, Type 2', 'Diet', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Milk', 'Risk Factors', 'Soy Milk', 'Triglycerides'] | 23,498,346 | [['M01.060.116'], ['B01.050'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.52... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Clinical analysis of chronic suppurative otitis media in adults and children]. | OBJECTIVE: To explore the differences and common features between adults and children with chronic suppurative otitis media in the course of disease, clinical characteristics and operation.METHOD: To compare and analyze the clinical information before the operation, the range of lesion and ossicular chain damage in adu... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Child', 'Child, Preschool', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Otitis Media, Suppurative', 'Young Adult'] | 16,200,829 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.830.694', 'C09.218.705.663.680'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A Novel Female-Specific and Sexual Reproduction-Associated Dmrt Gene Discovered in the Stony Coral, Euphyllia ancora. | Transcription factors encoded by the Dmrt gene family regulate multiple aspects of animal reproduction. Most studies investigating the Dmrt gene family were conducted in model organisms from bilateral species, with a particular emphasis on gene function in male sex determination. It is still unclear whether the E. anco... | ['Adenosine Triphosphate', 'Animals', 'Anthozoa', 'Female', 'Germ Cells', 'Phylogeny', 'Reproduction', 'Thionucleosides'] | 26,740,592 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['B01.050.500.308.237'], ['A05.360.490', 'A11.497'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G08.686.784'], ['D02.886.759', 'D13.570.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vitro metabolism of quazepam in human liver and intestine and assessment of drug interactions. | The study was carried out to identify and characterize kinetically the cytochrome P450 (CYP) enzymes responsible for the major metabolite formation of quazepam. In in vitro studies using human liver and intestinal microsomes and cDNA-expressed human CYP and FMO isoenzymes, quazepam was rapidly metabolized mainly by CYP... | ['Benzodiazepines', 'Cells, Cultured', 'Cytochrome P-450 Enzyme System', 'Humans', 'Intestinal Mucosa', 'Intestines', 'Kinetics', 'Liver', 'Metabolic Clearance Rate', 'Microsomes', 'Microsomes, Liver'] | 15,801,544 | [['D03.633.100.079.080'], ['A11.251'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of clinical babesiosis in an area in north Co Meath, Ireland. | A survey of clinical babesiosis was carried out in an area serviced by a veterinary practice in Oldcastle, Co Meath. Data were collected from the day books of the practice from 1970 to 1981 and from questionnaires and visits to farmers. Clinical incidence ranged between 3.2 and 4.9 per cent, which was very high compare... | ['Age Factors', 'Animals', 'Antiprotozoal Agents', 'Babesiosis', 'Cattle', 'Cattle Diseases', 'Epidemiologic Methods', 'Female', 'Ireland', 'Male', 'Surveys and Questionnaires'] | 6,665,958 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D27.505.954.122.250.100'], ['C01.610.701.688.122', 'C01.610.752.075', 'C01.610.752.625.122', 'C01.920.930.182', 'C22.674.710.122'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E05.318', 'N06.850.520'], ['Z01.542.467', 'Z01.639.587'], ['E05.318.308.980'... | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The Hamilton Inventory for Complex Regional Pain Syndrome: a cognitive debriefing study of the clinician-based component. | STUDY DESIGN: Descriptive.INTRODUCTION: The Hamilton Inventory for Complex Regional Pain Syndrome (HI-CRPS) is a multidisciplinary assessment tool under development.PURPOSE OF THE STUDY: This study examined the assessment practices, beliefs and preferences of health care professionals working with CRPS to inform the co... | ['Attitude of Health Personnel', 'Complex Regional Pain Syndromes', 'Humans', 'Interviews as Topic', 'Pain Measurement', 'Professional-Patient Relations'] | 22,265,445 | [['F01.100.050', 'N05.300.100'], ['C10.177.195', 'C10.668.829.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E01.370.600.550.324'], ['F01.829.401.650', 'N05.300.660']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[The role of transesophageal echocardiopgraphy in detection of cardiogenic and aortic sources of embolism in stroke and transient ischaemic attacks]. | OBJECTIVES: To prospectively investigate the prevalence of definite and potential sources of cardiogenic embolism and embolism from ascending aorta and aortic arch in patients with a cryptogenic stroke or transient ischaemic attack (TIA).MATERIAL/METHODS: The study group consisted of 218 consecutive patients (146 males... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aorta', 'Echocardiography, Transesophageal', 'Female', 'Heart Atria', 'Heart Diseases', 'Humans', 'Intracranial Embolism', 'Ischemic Attack, Transient', 'Male', 'Middle Aged', 'Stroke', 'Thrombosis'] | 16,623,277 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.114.056'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['A07.541.358'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.525.400', 'C14.907.253.566.300', 'C14.907.355.590.213.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of Fibroin Microcarriers on Inflammation and Regeneration of Deep Skin Wounds in Mice. | The process of tissue regeneration following damage takes place with direct participation of the immune system. The use of biomaterials as scaffolds to facilitate healing of skin wounds is a new and interesting area of regenerative medicine and biomedical research. In many ways, the regenerative potential of biological... | ['Animals', 'Cytokines', 'Female', 'Fibroins', 'Mice', 'Skin', 'Wound Healing', 'Wounds and Injuries'] | 27,914,451 | [['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D05.750.078.875.500', 'D12.776.093.750.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['A17.815'], ['G16.762.891'], ['C26']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antidepressant drug action in a transgenic mouse model of the endocrine changes seen in depression. | We have created transgenic mouse lines with impaired glucocorticoid receptor function by expression of a type II glucocorticoid receptor antisense RNA in brain tissues. These animals have endocrinological characteristics similar to those seen in depression, including a hyperactive hypothalamic-pituitary-adrenal axis as... | ['Actins', 'Animals', 'Brain', 'Depression', 'Desipramine', 'Disease Models, Animal', 'Endocrine Glands', 'Gene Expression', 'Hypothalamo-Hypophyseal System', 'Mice', 'Mice, Transgenic', 'Pituitary-Adrenal System', 'RNA, Antisense', 'RNA, Messenger', 'Receptors, Glucocorticoid'] | 1,480,137 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['A08.186.211'], ['F01.145.126.350'], ['D03.633.300.240.281'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A06.300'], ['G05.297'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Toward a broader definition of the age-of-onset criterion for attention-deficit hyperactivity disorder. | OBJECTIVE: To critique the age-of-onset criterion (AOC) for the diagnosis of attention-deficit hyperactivity disorder (ADHD).METHOD: The specific AOC of 7 years for symptoms producing impairment as part of the diagnostic criteria is examined from historical, empirical, conceptual, and pragmatic perspectives.RESULTS: No... | ['Adolescent', 'Age of Onset', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child Psychiatry', 'Humans', 'Manuals as Topic', 'Terminology as Topic'] | 9,291,721 | [['M01.060.057'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['F03.625.094.150'], ['M01.060.406'], ['F04.096.544.193', 'H02.403.690.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682.192.609', 'L01.178.820.500'], ['L01.559.598.400']] | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Renal transplantation following previous heart, liver, and lung transplantation: an 8-year single-center experience. | BACKGROUND: Long-term follow-up of heart, liver, and lung transplantation has led to an increased recognition of secondary end-stage renal failure (ESRF) in transplant recipients. This study examines our center's experience with renal transplantation following previous solid organ transplantation.METHODS: From January ... | ['Follow-Up Studies', 'Graft Survival', 'Heart Transplantation', 'Humans', 'Immunosuppression', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Liver Transplantation', 'Lung Transplantation', 'Reoperation', 'Survival Analysis'] | 11,562,670 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.340'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.450', 'E05.478.610'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro and in vivo effects of prestorage filtration of apheresis platelets. | BACKGROUND: The effect of prestorage filtration on the quality of apheresis platelet concentrates stored for transfusion is undetermined.STUDY DESIGN AND METHODS: Investigation of 11 plateletpheresis components used a concurrent paired-study design. On the day of collection, each component was equally divided into two ... | ['Blood Platelets', 'Blood Preservation', 'Filtration', 'Humans', 'Leukocytes', 'Plateletpheresis', 'Time Factors'] | 7,825,207 | [['A11.118.188', 'A15.145.229.188'], ['E02.792.833.230', 'E05.760.833.230'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['E02.095.160.790', 'E02.120.285.790', 'E05.200.500.363.171.790', 'E05.242.363.171.790'], ['G01.910.857'... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multilevel bioluminescence tomography based on radiative transfer equation Part 1: l1 regularization. | In this paper we study an l1-regularized multilevel approach for bioluminescence tomography based on radiative transfer equation with the emphasis on improving imaging resolution and reducing computational time. Simulations are performed to validate that our algorithms are potential for efficient high-resolution imagin... | ['Algorithms', 'Computer Simulation', 'Diffusion', 'Luminescent Measurements', 'Models, Chemical', 'Radiation', 'Tomography'] | 20,174,013 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['G01.202', 'G02.196'], ['E05.196.712.516'], ['E05.599.495'], ['G01.750'], ['E01.370.350.825']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Laparoscopic removal of a remaining myoma after vaginal hysterectomy: a case report. | We report on an uncommon postoperative complication of vaginal hysterectomy--a remaining myoma--diagnosed and treated by laparoscopy. This procedure was performed for a remaining myoma 3 months after vaginal hysterectomy for fibroid uterus. Laparoscopy may be helpful to diagnose and treat this complication. | ['Female', 'Humans', 'Hysterectomy, Vaginal', 'Laparoscopy', 'Leiomyoma', 'Middle Aged', 'Reoperation', 'Uterine Neoplasms'] | 16,036,202 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399.380'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C04.557.450.590.450'], ['M01.060.116.630'], ['E04.690'], ['C04.588.945.418.948', 'C13.351.500.852.762', 'C13.351.937.418.875']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Healthcare utilization in adults with opioid dependence receiving extended release naltrexone compared to treatment as usual. | BACKGROUND: Opioid use disorders have reached epidemic proportions, with overdose now the leading cause of accidental death in the United States. Extended release naltrexone (XR-NTX) has emerged as a medication treatment that reduces opioid use and craving. However, the effect of XR-NTX therapy on acute healthcare util... | ['Adult', 'Criminal Law', 'Delayed-Action Preparations', 'Female', 'Humans', 'Male', 'Naltrexone', 'Narcotic Antagonists', 'Opioid-Related Disorders', 'Patient Acceptance of Health Care', 'Patient Admission', 'Randomized Controlled Trials as Topic', 'Retrospective Studies', 'United States'] | 28,576,389 | [['M01.060.116'], ['I01.198.290', 'I01.880.604.583.100'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.577.249.706.550', 'D03.605.497.750.550', 'D03.633.400.686.750.550', 'D04.615.723.795.706.550'], ['D27.505.696.543', 'D27.505.696.663.850.512', 'D27.505.954.427.550'], ... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Do HMOs affect educational disparities in health care? | BACKGROUND: We wanted to examine how membership in a health maintenance organization (HMO) is related to delivery of preventive clinical services to patients with different educational levels.METHODS: We conducted a cross-sectional analysis of the 1996-1997 Community Tracking Study Household Survey among adults aged 18... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Data Collection', 'Delivery of Health Care', 'Fee-for-Service Plans', 'Female', 'Health Maintenance Organizations', 'Health Services Accessibility', 'Humans', 'Insurance, Health', 'Male', 'Middle Aged', 'Patient Acceptance of Health Care', 'Patient Education as Topic'... | 15,040,438 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N04.590.374', 'N05.300'], ['N03.219.442.195', 'N03.219.521.710.305.090', 'N04.452.758.745.225'], ['N03.219.521.576.343.800.400', 'N03.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
[Iron and copper in Plagioscion squamosissimus (Piscis: Sciaenidae) from the Orinoco river, Venezuela]. | Bauxite explotation of the Orinoco River in recent years is an important source of heavy metals discharge in the ecosystem, changing the natural biochemical flow of these elements and their concentrations in water, sediment and organisms. Iron and copper concentrations were measured in the fish Plagioscion squamosissim... | ['Animals', 'Copper', 'Environmental Monitoring', 'Fishes', 'Iron', 'Mining', 'Rivers', 'Time Factors', 'Venezuela', 'Water Pollution, Chemical'] | 15,266,810 | [['B01.050'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.493'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['J01.576.655.875.500'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['G01.910.857'], ['Z01.107.757.943'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
The challenge of managed care and managed competition. | Payment for health care in the United States changed rapidly during the 1980s, with the changes often identified by three-letter acronyms such as HMO, PPO, DRG, and RVS (health maintenance organization, preferred provider organization, diagnosis-related group, and relative value system). Changes are likely to be even m... | ['Competitive Medical Plans', 'Health Care Reform', 'Humans', 'Managed Care Programs', 'Radiology', 'United States'] | 8,140,988 | [['N03.219.521.576.343.800.175', 'N04.590.374.410.175'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['H02.403.740'], ['Z01.107.567... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Estimation of intrinsically disordered protein shape and time-averaged apparent hydration in native conditions by a combination of hydrodynamic methods. | Size exclusion chromatography coupled online to a Tetra Detector Array in combination with analytical ultracentrifugation (or with quasi-elastic light scattering) is a useful methodology to characterize hydrodynamic properties of macromolecules, including intrinsically disordered proteins. The time-averaged apparent hy... | ['Chemistry Techniques, Analytical', 'Chromatography, Gel', 'Hydrodynamics', 'Light', 'Proteins', 'Scattering, Radiation', 'Spectrophotometry', 'Time Factors', 'Ultracentrifugation', 'Water'] | 22,821,523 | [['E05.196'], ['E05.196.181.400.250'], ['G01.342'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D12.776'], ['E05.196.822', 'G01.867'], ['E05.196.712.726', 'E05.196.867.826'], ['G01.910.857'], ['E05.181.724', 'E05.196.941'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal transplantation in patients with renal cell carcinoma and von Hippel-Lindau disease. | This study reviewed the management and outcome of patients with von Hippel-Lindau disease (VHLD) who underwent renal transplantation after being rendered anephric to treat multifocal bilateral renal cell carcinoma (RCC). Five patients with bilateral RCC and VHLD underwent renal transplantation at our hospital. Initial ... | ['Adult', 'Carcinoma, Renal Cell', 'Combined Modality Therapy', 'Follow-Up Studies', 'Humans', 'Immunosuppression', 'Kidney Neoplasms', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm, Residual', 'Nephrectomy', 'Postoperative Complications', 'Renal Dialysis', 'von Hippel-Lindau ... | 7,974,953 | [['M01.060.116'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E02.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mechanism of exacerbative effect of progesterone on drug-induced liver injury. | Drug-induced liver injury (DILI) is a major safety concern in drug development and clinical drug therapy. However, the underlying mechanism of DILI is little known. It is generally believed that women exhibit worse outcomes from DILI than men. Recently, we found that pretreatment of mice with estradiol attenuated halot... | ['Animals', 'Cell Line, Transformed', 'Chemical and Drug Induced Liver Injury', 'Crosses, Genetic', 'Female', 'Gene Expression Regulation', 'Hormone Antagonists', 'Inflammation Mediators', 'Intercellular Adhesion Molecule-1', 'Kupffer Cells', 'Leukocytes, Mononuclear', 'Liver', 'MAP Kinase Signaling System', 'Macrophag... | 22,157,104 | [['B01.050'], ['A11.251.210.172'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['E05.393.281'], ['G05.308'], ['D06.347', 'D27.505.696.399.450'], ['D23.469'], ['D12.776.395.550.200.450', 'D12.776.543.550.200.450', 'D23.050.301.350.450'], ['A11.329.372.588', 'A11.627.482.588', 'A11.733.397.588', 'A15.382.670.522.588',... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Depiction of facial nerve paresis in the gallery of portraits carved in stone by George Matthew the Dalmatian on the Sibenik Cathedral dating from the 15th century. | The introductory segment of this paper briefly describes George Matthew the Dalmatian, the architect who, between 1441 and 1473, oversaw the construction of the Cathedral of St. James in Sibenik, a city on the Croatian side of the Adriatic coast. Of the most impressive details included in this monumental construction a... | ['Croatia', 'Facial Nerve Diseases', 'History, 15th Century', 'Humans', 'Male', 'Sculpture'] | 21,755,741 | [['Z01.542.248.295'], ['C07.465.299', 'C10.292.319'], ['K01.400.475.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.093.849']] | ['Geographicals [Z]', 'Diseases [C]', 'Humanities [K]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Defining optimum lipophilicity and molecular weight ranges for drug candidates-Molecular weight dependent lower logD limits based on permeability. | Analysis of a large, structurally diverse Caco-2 permeability dataset using a variety of statistical techniques suggests that logD and molecular weight are the most important factors in determining the permeability of drug candidates. The limit for logD is shown to be dependent on molecular weight. These limits are sho... | ['Algorithms', 'Caco-2 Cells', 'Cell Membrane Permeability', 'Drug Design', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Molecular Weight', 'Pharmaceutical Preparations'] | 19,361,989 | [['G17.035', 'L01.224.050'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['G03.143.335', 'G04.175'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['G02.494'], ['D26']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Identity of a newly isolated human polyomavirus from a patient with progressive multifocal leucoencephalopathy. | Isolation of a strain of polyomavirus, designated COL, from the brain of a patient with progressive multifocal leucoencephalopathy is described. The COL strain is antigenically similar to JC polyomavirus, previously isolated from a brain affected by progressive multifocal leucoencephalopathy and is unrelated to BK, ano... | ['Agglutination Tests', 'Antigens, Viral', 'Brain', 'Cytopathogenic Effect, Viral', 'Humans', 'Leukoencephalopathy, Progressive Multifocal', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Papillomaviridae', 'Polyomaviridae', 'Polyomavirus', 'Simian virus 40'] | 4,368,786 | [['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['D23.050.327'], ['A08.186.211'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.207.245.340.500', 'C01.207.399.750.500', 'C01.925.182.525.500', 'C01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Compliance with referral of sick children: a survey in five districts of Afghanistan. | BACKGROUND: Recognition and referral of sick children to a facility where they can obtain appropriate treatment is critical for helping reduce child mortality. A well-functioning referral system and compliance by caretakers with referrals are essential. This paper examines referral patterns for sick children, and facto... | ['Acute Disease', 'Afghanistan', 'Caregivers', 'Child, Preschool', 'Diarrhea', 'Fever', 'Health Care Surveys', 'Health Services Accessibility', 'Humans', 'Infant', 'Infant, Newborn', 'Parents', 'Patient Compliance', 'Referral and Consultation', 'Respiratory Tract Infections', 'Rural Health Services'] | 22,540,424 | [['C23.550.291.125'], ['Z01.252.245.500.125'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406.448'], ['C23.888.821.214'], ['C23.888.119.344'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.... | ['Diseases [C]', 'Geographicals [Z]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Antioxidant defense system in familial hypercholesterolemia and the effects of lipoprotein apheresis. | Oxidative stress is thought to play an important role in the pathogenesis of disorders associated with atherosclerosis. Alpha-tocopherol is considered to be an effective lipophilic antioxidant, which protects lipid membranes against peroxidation and thus prevents cell damage by reaction with free radicals. However, mea... | ['Adult', 'Aged', 'Antioxidants', 'Biomarkers', 'Blood Component Removal', 'Case-Control Studies', 'Chromatography, High Pressure Liquid', 'Chromatography, Reverse-Phase', 'Erythrocyte Membrane', 'Female', 'Humans', 'Hyperlipoproteinemia Type II', 'Lipid Peroxidation', 'Lipoproteins', 'Male', 'Middle Aged', 'Oxidative ... | 29,096,832 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D23.101'], ['E02.120'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.196.181.400.300'], ['E05.196.181.400.495'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of the effect of food and beverages on enamel and restorative materials by SEM and Fourier transform infrared spectroscopy. | OBJECTIVES: To examine different types of restorative materials used in children as well as primary and permanent teeth enamel when affected by erosive foods.MATERIALS AND METHOD: Buttermilk, fruit yoghurt, Coca-cola, fruit juice, Filtek Z-250, Dyract Extra, Fuji II LC, and Fuji IX and tooth enamel were used. Measureme... | ['Beverages', 'Dental Cements', 'Dental Enamel', 'Dental Restoration, Permanent', 'Food', 'Humans', 'Hydrogen-Ion Concentration', 'Microscopy, Electron, Scanning', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties', 'Tooth Erosion'] | 24,218,060 | [['G07.203.100', 'J02.200'], ['D25.339.291', 'J01.637.051.339.291'], ['A14.549.167.900.255'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E05.196.712.726.676.700', 'E05.... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The value of continuous ECG monitoring during treatment of diabetic ketoacidosis. A computer study. | In order to confirm or refute the previously held view that electrocardiographic (ECG) abnormalities are frequent in diabetic ketoacidosis, we have undertaken continuous ECG monitoring for 24 h, with subsequent computer analysis, in 14 diabetic patients admitted with severe ketoacidosis. There was a steady fall in hear... | ['Adolescent', 'Adult', 'Aged', 'Arrhythmias, Cardiac', 'Diabetic Ketoacidosis', 'Diagnosis, Computer-Assisted', 'Electrocardiography', 'Female', 'Heart Rate', 'Humans', 'Insulin', 'Male', 'Middle Aged'] | 102,099 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Differences in Ca(2+)-handling and sarcoplasmic reticulum Ca(2+)-content in isolated rat and rabbit myocardium. | We made novel measurements of the influence of rest intervals and stimulation frequency on twitch contractions and on sarcoplasmic reticulum (SR) Ca(2+)-content (using rapid cooling contractures, RCCs) in isolated ventricular muscle strips from rat and rabbit hearts at a physiological temperature of 37 degrees C. In ad... | ['Animals', 'Calcium', 'Cold Temperature', 'Electrophysiology', 'Muscle Fibers, Skeletal', 'Myocardial Contraction', 'Myocardium', 'Rabbits', 'Rats', 'Rats, Sprague-Dawley', 'Sarcoplasmic Reticulum', 'Temperature', 'Time Factors'] | 11,113,000 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['H01.158.344.528', 'H01.158.782.236'], ['A10.690.552.500.500', 'A11.620.249'], ['G09.330.580', 'G11.427.494.570']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Heterotopic mediastinal goitre. | The unusual coexistence in a woman of 34 years of a cervical thyroid and a heterotopic mediastinal thyroid is recorded. Both thyroids had undergone non-toxic nodular enlargement. Recurrent enlargement was noted in the cervical gland 12 months after transpleural thoracic removal of the mediastinal goitre, whilst no corr... | ['Adult', 'Choristoma', 'Female', 'Goiter, Nodular', 'Humans', 'Mediastinal Neoplasms', 'Recurrence', 'Thyroid Gland', 'Time Factors'] | 667,546 | [['M01.060.116'], ['C23.300.250'], ['C19.874.283.501'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.479', 'C08.846.187.580'], ['C23.550.291.937'], ['A06.300.900'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Involvement of Ca²⁺ and ATP in enhanced gene delivery by bubble liposomes and ultrasound exposure. | Recently, we reported the accelerated gene transfection efficiency of laminin-derived AG73-peptide-labeled polyethylene glycol-modified liposomes (AG73-PEG liposomes) and cell penetrating TAT-peptide labeled PEG liposomes using PEG-modified liposomes, which trap echo-contrast gas, "Bubble liposomes" (BLs), and ultrasou... | ['Adenosine Triphosphate', 'Calcium', 'Cell Line', 'Gene Transfer Techniques', 'Humans', 'Liposomes', 'Transfection', 'Ultrasonics'] | 22,384,937 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['E05.393.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['E05.393.350.810', ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Endoscopic submucosal dissection with a combination of small-caliber-tip transparent hood and flex knife for large superficial colorectal neoplasias including ileocecal lesions. | BACKGROUND: Large superficial neoplasias of the ileocecal region pose an increased degree of complexity for endoscopic resection. This study aimed to evaluate the safety and efficacy of endoscopic submucosal dissection (ESD) for large superficial colorectal neoplasias including ileocecal lesions.METHODS: A total of 33 ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cecal Neoplasms', 'Colorectal Neoplasms', 'Endoscopes, Gastrointestinal', 'Equipment Design', 'Female', 'Humans', 'Ileal Neoplasms', 'Intestinal Mucosa', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Retrospective Studies'] | 20,112,112 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.184', 'C06.301.371.411.184', 'C06.405.249.411.184', 'C06.405.469.110.417', 'C06.405.469.491.184'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.86... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The well-man visit: addressing a man's health to optimize pregnancy outcomes. | Male health and health care before conception has received little attention by many physicians. Only recently has the importance of the health of men before conception been explored. The benefits of preconception care are important, including ensuring that all pregnancies are planned and wanted, improving the man's gen... | ['Female', 'Health Promotion', 'Humans', 'Infertility, Male', 'Male', "Men's Health", 'Physical Examination', 'Pregnancy', 'Pregnancy Outcome', 'Reproductive Health'] | 23,471,934 | [['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['N01.400.425'], ['E01.370.600'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['N01.400.625']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
An experimental model of osteoarthrosis of the temporomandibular joint in monkeys. | The purpose of this study was to develop a model of osteoarthrosis of the temporomandibular joint in monkeys, which is remarkably similar in structure and function to that of humans. Nine juvenile monkeys, two as controls and seven as an experimental group, were used in this study. In the experimental group, the articu... | ['Animals', 'Bone Marrow', 'Bone Plates', 'Cartilage Diseases', 'Cartilage, Articular', 'Chondrocytes', 'Disease Models, Animal', 'Fibrosis', 'Follow-Up Studies', 'Humans', 'Hyalin', 'Joint Dislocations', 'Macaca', 'Mandibular Condyle', 'Osteoarthritis', 'Osteotomy', 'Temporal Bone', 'Temporomandibular Joint', 'Temporo... | 12,054,715 | [['B01.050'], ['A15.382.216'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['C05.182', 'C17.300.182'], ['A02.165.407.150', 'A02.835.583.192'], ['A11.329.171'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.355'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.8... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The colonization of the Pacific: the story according to human leukocyte antigens. | The human leukocyte antigen (HLA) distributions in 16 Pacific populations have been collated from published and unpublished reports. Gene frequency and linkage disequilibrium relationships among groups show that Australians and Papuans share a common ancestry, that coastal Melanesia has about 16% Austronesian admixture... | ['Australia', 'Emigration and Immigration', 'Gene Frequency', 'Genetic Linkage', 'Genetics, Population', 'HLA Antigens', 'Humans', 'Oceanic Ancestry Group', 'Pacific Islands'] | 7,180,847 | [['Z01.639.100', 'Z01.678.100.373'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['G05.330'], ['G05.348'], ['H01.158.273.343.335'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.600'], ['Z01.639.760', 'Z01.678.100.873']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
How does the mite Varroa destructor kill the honeybee Apis mellifera? Alteration of cuticular hydrcarbons and water loss in infested honeybees. | Several factors threaten the health of honeybees; among them the parasitic mite Varroa destructor and the Deformed Wing Virus play a major role. Recently, the dangerous interplay between the mite and the virus was studied in detail and the transition, triggered by mite feeding, from a benign covert infection to a devas... | ['Animals', 'Bees', 'Body Weight', 'Female', 'Host-Parasite Interactions', 'Humidity', 'Hydrocarbons', 'Insect Viruses', 'Varroidae', 'Virus Diseases', 'Water', 'Wings, Animal'] | 23,041,382 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G16.527.200.400'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['D02.455'], ['B04.525'],... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bacteraemia in febrile out-patient children. | In order to study the occurrence of bacteraemia, 634 consecutively febrile children aged less than or equal to 14 years with Initial rectal temperature or 39 degrees C and above were evaluated. The overall frequency of bacteraemia was 7.7% (49 cases). Salmonellae, Streptococci and Staphylococci accounted for 57%, 16% a... | ['Adolescent', 'Age Factors', 'Bacteremia', 'Child', 'Child, Preschool', 'Ethiopia', 'Female', 'Fever', 'Hospitals, Military', 'Hospitals, University', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Outpatient Clinics, Hospital', 'Prospective Studies'] | 1,505,391 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.058.290.120.310'], ['C23.888.119.344'], ['N02.278.421.510.180.250'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Differential regulation of single CFTR channels by PP2C, PP2A, and other phosphatases. | Cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel activity declines rapidly when excised from transfected Chinese hamster ovary (CHO) or human airway cells because of membrane-associated phosphatase activity. In the present study, we found that CFTR channels usually remained active in patches excis... | ['Animals', 'Animals, Newborn', 'CHO Cells', 'Cell Line', 'Cricetinae', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Electrophysiology', 'Enzyme Inhibitors', 'Humans', 'Ion Channels', 'Kidney', 'Magnesium', 'Marine Toxins', 'Oxazoles', 'Patch-Clamp Techniques', 'Phosphoprotein Phosphatases', 'Phosphoric Mono... | 9,612,228 | [['B01.050'], ['B01.050.050.282'], ['A11.251.210.200', 'A11.436.155'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500', 'D12.776.543.585.40... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Release of PAF by human polymorphonuclear leucocytes stimulated by immune complexes bound to Sepharose particles and human erythrocytes. | Human polymorphonuclear leucocytes (PMN) incubated with surface-bound immune complexes (IC) release a substance that induces platelet aggregation and serotonin-release. This substance was identified as platelet-activating factor (PAF) on the basis of its sensitivity to phospholipase A2 and of its purification by thin-l... | ['Animals', 'Antigen-Antibody Complex', 'Erythrocytes', 'Humans', 'Indomethacin', 'Neutrophils', 'Phospholipases A', 'Phospholipases A2', 'Platelet Activating Factor', 'Platelet Aggregation', 'Rabbits', 'Serotonin', 'Zymosan'] | 6,885,111 | [['B01.050'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.420'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimisation of low temperature extraction of banana juice using commercial pectinase. | The objective of this work was to develop a process with optimum conditions for banana juice. The procedure involves hydrolyzing the banana pulp by commercial pectinase followed by cloth filtration. Response surface methodology with Doehlert design was utilised to optimize the process parameters. The temperature of inc... | ['Cold Temperature', 'Dietary Carbohydrates', 'Musa', 'Polygalacturonase'] | 24,423,519 | [['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['B01.650.940.800.575.912.250.618.937.555.500'], ['D08.811.277.450.800']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Glycosylation pattern and cell attachment-inhibiting property of human salivary mucins. | BACKGROUND: Whole human saliva (WHS) and its high molecular weight mucin constituent (Muc) inhibit fibroblast attachment and might influence periodontal and peri-implant wound healing. The aim of this work was to study the potential role of glycosylation of Muc in fibroblast attachment-inhibiting property and to examin... | ['Cell Adhesion', 'Cells, Cultured', 'Electrophoresis, Agar Gel', 'Epithelial Attachment', 'Fibroblasts', 'Gingiva', 'Glycoproteins', 'Glycoside Hydrolases', 'Glycosylation', 'Humans', 'Keratinocytes', 'Molecular Weight', 'Mucins', 'Salivary Proteins and Peptides', 'Wound Healing'] | 16,018,762 | [['G04.022'], ['A11.251'], ['E05.196.401.153', 'E05.301.300.100'], ['A14.549.167.646.374'], ['A11.329.228'], ['A14.549.167.646.480'], ['D09.400.430', 'D12.776.395'], ['D08.811.277.450'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.500', 'A11.436.397'], [... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Dental services in bronchial asthma patients and the ways to improve them]. | The study was conducted in 783 bronchial asthma patients which have been established to need treatment of caries and its complications in 95.4±0.84% of cases. The received data suggest that it is possible to achieve a highly efficient treatment of caries and its complications in patients suffering from bronchial asthma... | ['Asthma', 'Dental Care', 'Dental Caries', 'Humans', 'Russia'] | 22,968,607 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E06.170', 'N02.421.240.190'], ['C07.793.720.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Properties of cellulose nanocrystals from oil palm trunk isolated by total chlorine free method. | Cellulose nanocrystals were isolated from oil palm trunk by total chlorine free method. The samples were either water pre-hydrolyzed or non-water pre-hydrolyzed, subjected to soda pulping, acidified and ozone bleached. Cellulose and cellulose nanocrystal (CNC) physical, chemical, thermal properties, and crystallinity i... | ['Arecaceae', 'Cellulose', 'Hydrolysis', 'Nanoparticles', 'Plant Stems', 'Water'] | 27,842,840 | [['B01.650.940.800.575.912.250.093'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['G02.380'], ['J01.637.512.600'], ['A18.024.937'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
CT-guided biopsies: quality, complications and impact on treatment: a retrospective initial quality control. | PURPOSE: To retrospectively evaluate the quality and complications of CT-guided biopsies and their impact on treatment.MATERIALS AND METHODS: A total of 265 CT-guided interventions performed during a 6-month period were extracted by digital database query. These included 127 CT-guided biopsies, which were classified by... | ['Adult', 'Aged', 'Biopsy, Needle', 'Clinical Competence', 'Female', 'Germany', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Quality Control', 'Quality Indicators, Health Care', 'Radiography, Interventional', 'Retrospective Studies', 'Sensitivity and Specificity', 'Surgery, Computer-Assisted', 'Tomography, X-Ray Comp... | 21,830,181 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['Z01.542.315'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Expression polymerase chain reaction for the in vitro synthesis and epitope mapping of autoantigen. Application to the human thyrotropin receptor. | The clinical applicability of a newly described polymerase chain reaction directed protein expression system was assessed for the in vitro synthesis and partial epitope mapping of large radiolabeled human thyrotropin receptor (hTSH-R) protein segments. PCR amplification of targeted regions within the hTSH-R cDNA follow... | ['Amino Acid Sequence', 'Autoantigens', 'Base Sequence', 'Epitopes', 'Humans', 'In Vitro Techniques', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Receptors, Thyrotropin', 'Recombinant Proteins'] | 7,679,129 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.422'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D23.050.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['L01.453.245.667'], ['E05.393.620.500'], ['D12.776.543.750.720.600.850', 'D12.776.543.750.750.555.850', 'D12.776.543.75... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of tebufenozide on some aspects of lake trout (Salvelinus namaycush) immune response. | Tebufenozide is a nonsteroid ecdysone agonist that causes premature and incomplete molting in Lepidoptera and is used on crops and in forest spray programs. Lake trout (Salvelinus namaycush) were exposed to one pulse of 0.25 ppm tebufenozide every 3 days (12 pulses in total). Cell ratios and respiratory burst responses... | ['Animals', 'Fish Proteins', 'Hydrazines', 'Hydrocortisone', 'Insecticides', 'Leukocyte Count', 'Leukocytes', 'Respiratory Burst', 'Salmonidae', 'Water Pollutants, Chemical'] | 17,537,512 | [['B01.050'], ['D12.776.325'], ['D02.442'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D27.720.031.700.491', 'D27.888.723.491'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhanced in vitro refolding of soluble human glucocorticoid-induced TNF receptor-related ligand. | The glucocorticoid-induced tumor necrosis factor receptor (GITR) is a member of the tumor necrosis factor receptor superfamily. Attachment of GITR to its ligand (GITRL) regulates diverse biological functions, including cell proliferation, differentiation, and survival. In this study, the extracellular region of human G... | ['Brain', 'DNA, Complementary', 'Escherichia coli', 'Genetic Vectors', 'Glucocorticoid-Induced TNFR-Related Protein', 'Humans', 'Inclusion Bodies', 'Ligands', 'Phosphorylation', 'Protein Folding', 'Protein Multimerization', 'Recombinant Proteins', 'Tumor Necrosis Factors', 'U937 Cells'] | 23,613,116 | [['A08.186.211'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.337'], ['D12.776.543.750.705.852.760.238'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.420'], ['D27.720.470.480'], ['G02.111.665', 'G02.607.7... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Calcilytic compounds: potent and selective Ca2+ receptor antagonists that stimulate secretion of parathyroid hormone. | Despite the discovery of many ions and molecules that activate the Ca2+ receptor, there are no known ligands that block this receptor. Reported here are the pharmacodynamic properties of a small molecule, NPS 2143, which acts as an antagonist at the Ca2+ receptor. This compound blocked (IC50 of 43 nM) increases in cyto... | ['Aniline Compounds', 'Animals', 'Calcium', 'Calcium-Binding Proteins', 'Cattle', 'Cell Line', 'Extracellular Space', 'GTP-Binding Proteins', 'Humans', 'Male', 'Naphthalenes', 'Parathyroid Glands', 'Parathyroid Hormone', 'Rats', 'Rats, Sprague-Dawley', 'Stimulation, Chemical'] | 11,561,095 | [['D02.092.146'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.125'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['A10.082.500', 'A11.284.295'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.847.638'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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