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Prospects for a novel ultrashort pulsed laser technology for pathogen inactivation. | The threat of emerging pathogens and microbial drug resistance has spurred tremendous efforts to develop new and more effective antimicrobial strategies. Recently, a novel ultrashort pulsed (USP) laser technology has been developed that enables efficient and chemical-free inactivation of a wide spectrum of viral and ba... | ['Bacteria', 'Humans', 'Lasers', 'Sterilization', 'Vaccines, Inactivated', 'Viruses'] | 22,768,792 | [['B03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490', 'E07.710.520'], ['N06.850.780.200.450.850'], ['D20.215.894.830'], ['B04']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
ERCC1 predicts outcome in patients with gastric cancer treated with adjuvant cisplatin-based chemotherapy. | BACKGROUND: Adjuvant chemotherapy is gaining an increasing role in resectable gastric cancer. Customizing chemotherapy on the basis of chemosensitivity may improve outcome, and putative predictive molecular markers have been mostly evaluated in Asian patients. We profiled key DNA and damage signaling factors and correl... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Biomarkers, Tumor', 'Chemotherapy, Adjuvant', 'Cisplatin', 'Cohort Studies', 'DNA-Binding Proteins', 'Endonucleases', 'Europe', 'Female', 'Follow-Up Studies', 'Gastric Mucosa', 'Humans', 'Male', 'Middle Aged'... | 23,645,290 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D23.101.140'], ['E02.186.170', 'E02.319.170'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], [... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Generation of functional T-regulatory cells in children with metabolic syndrome. | Recent research implies a role of decreased number and/or function of T-regulatory cells (Tregs) in low-grade inflammation associated with obesity and atherosclerosis. The enhancement of atheroprotective immunity by the expansion of Tregs could serve as a therapeutic strategy in obesity-related immunological disturbanc... | ['Adolescent', 'Age Factors', 'Antibodies', 'CD28 Antigens', 'CD3 Complex', 'Case-Control Studies', 'Cell Proliferation', 'Cells, Cultured', 'Female', 'Forkhead Transcription Factors', 'Gene Expression Regulation', 'Humans', 'Interleukin-2', 'Lymphocyte Activation', 'Male', 'Metabolic Syndrome', 'Obesity', 'RNA, Messen... | 23,052,042 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.543.750.705.222.500', 'D23.050.301.264.894.128', 'D23.101.100.894.128'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['E05.318.372.500.500', 'N05.715.360.330.500... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Specific peripheral miRNA profiles for distinguishing lung cancer from COPD. | Recently we reported differential miRNA signatures in blood cells of lung cancer patients and healthy controls. With the present study we wanted to investigate if miRNA blood signatures are also suited to differentiate lung cancer patients from COPD patients. We compared the expression of 863 human miRNAs in blood cell... | ['Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma', 'Diagnosis, Differential', 'Disease Progression', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Leukocytes, Mononuclear', 'Lung Neoplasms', 'Male', 'MicroRNAs', 'Microarray Analysis', 'Middle Aged', 'Neoplasm M... | 21,388,703 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.557.470.200'], ['E01.171'], ['C23.550.291.656'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A). | Transmembrane protein 16A (TMEM16A), also called anoctamin 1 (ANO1), is a calcium-activated chloride channel expressed widely mammalian cells, including epithelia, vascular smooth muscle tissue, electrically excitable cells, and some tumors. TMEM16A inhibitors have been proposed for treatment of disorders of epithelial... | ['Animals', 'Anoctamin-1', 'Carboxylic Acids', 'Cells, Cultured', 'Chloride Channels', 'Humans', 'Rats', 'Rats, Inbred F344', 'Structure-Activity Relationship', 'Thiophenes'] | 28,493,701 | [['B01.050'], ['D12.776.157.530.400.175.032.500', 'D12.776.543.550.450.175.032.500', 'D12.776.543.585.400.175.032.500'], ['D02.241'], ['A11.251'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.700... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Therapies for inborn errors of metabolism: what has the orphan drug act delivered? | OBJECTIVE: The 1983 US Orphan Drug Act established a process through which promising therapies are designated as orphan products and, later, with satisfactory safety and efficacy data, receive marketing approval and fiscal incentives. We examined accomplishments in drug development for inborn errors of metabolism (IEMs... | ['Child', 'Child, Preschool', 'Drug Approval', 'Drug-Related Side Effects and Adverse Reactions', 'Drugs, Investigational', 'Female', 'Forecasting', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Metabolism, Inborn Errors', 'Needs Assessment', 'Orphan Drug Production', 'United States', 'United States Food and Drug Adm... | 20,566,615 | [['M01.060.406'], ['M01.060.406.448'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['C25.100'], ['D26.371'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C16.320.565', 'C18.452.648'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['J01.576.655.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Prescribers' knowledge of and sources of information for potential drug-drug interactions: a postal survey of US prescribers. | BACKGROUND: Given the high prevalence of medication use in the US, the risk of drug-drug interactions (DDIs) and potential for patient harm is of concern. Despite the rise in technologies to identify potential DDIs, the ability of physicians and other prescribers to recognize potential DDIs is essential to reduce their... | ['Arizona', 'Data Collection', 'Data Interpretation, Statistical', 'Drug Interactions', 'Drug Prescriptions', 'Female', 'Health Care Surveys', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Insurance, Pharmaceutical Services', 'Male', 'Medical Records Systems, Computerized', 'Nurse Practitioners', 'Physicians', 'R... | 18,484,786 | [['Z01.107.567.875.760.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['G07.690.773.968'], ['E02.319.307', 'N02.421.668.778.500'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.42... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Growth rates and life histories in twenty-two small-scale societies. | This study investigates variation in body growth (cross-sectional height and weight velocity) among a sample of 22 small-scale societies. Considerable variation in growth exists among hunter-gatherers that overlaps heavily with growth trajectories present in groups focusing more on horticulture. Intergroup variation te... | ['Adolescent', 'Adult', 'Body Height', 'Body Weight', 'Child', 'Child, Preschool', 'Ethnology', 'Female', 'Growth Disorders', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Multivariate Analysis', 'Retrospective Studies', 'Survival Rate'] | 16,634,027 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['M01.060.406.448'], ['I01.076.201.450.457'], ['C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cyclic nucleotides in chicken peripheral blood lymphocytes. | The influence of irradiation or surgical removal of one of two central lymphatic organs (thymus, bursa) on cAMP and cGMP intracellular concentration in chicken lymphocytes was studied. Results revealed drastic changes mainly in cAMP concentration in thymectomized or bursectomized chickens. Possible consequences of the ... | ['Animals', 'Animals, Newborn', 'Bursa of Fabricius', 'Cell Differentiation', 'Cyclic AMP', 'Cyclic GMP', 'Lymphocytes', 'Thymectomy', 'Thymus Gland'] | 1,666,505 | [['B01.050'], ['B01.050.050.282'], ['A10.549.175', 'A13.163', 'A15.382.520.604.114'], ['G04.152'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['A11.118.637.555.567', '... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lymphoma Involving Skin and Subcutaneous Fat of the Breast: Two Cases. | Breast lymphoma is uncommon, and it usually involves breast parenchyma and ipsilateral axillary lymph nodes. We report rare cases of cutaneous T-cell lymphoma involving the skin and subcutaneous fat layers mimicking panniculitis of the breasts in a 33-year-old male patient who presented with a growing palpable mass and... | ['Adolescent', 'Adult', 'Biopsy', 'Breast', 'Breast Neoplasms', 'Breast Neoplasms, Male', 'Female', 'Humans', 'Lymphoma, T-Cell, Cutaneous', 'Male', 'Mammography', 'Positron Emission Tomography Computed Tomography', 'Skin', 'Subcutaneous Fat', 'Ultrasonography, Mammary'] | 29,189,695 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['C04.588.180.260', 'C17.800.090.500.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Introducing ZORA to Children with Severe Physical Disabilities. | The aim of the present study was to explore the potential of a ZORA-robot based intervention in rehabilitation and special education for children with (severe) physical disabilities from the professionals perspective. The qualitative results of this study will be presented. Professionals indicated meaningful applicatio... | ['Child', 'Communication', 'Disabled Children', 'Humans', 'Interpersonal Relations', 'Learning', 'Robotics'] | 28,873,846 | [['M01.060.406'], ['F01.145.209', 'L01.143'], ['M01.150.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.425', 'F02.784.629.529'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
[Association of socio-demographic factors with the age at death due to cardiovascular diseases]. | BACKGROUND: The association of cardiovascular diseases with socio-demographic factors has not been fully explored.AIM: To analyze the association of socio-demographic features with the survival time of individuals who died due to cardiovascular diseases.MATERIAL AND METHODS: The death registries published by the Minist... | ['Adolescent', 'Adult', 'Age Distribution', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Cause of Death', 'Child', 'Child, Preschool', 'Chile', 'Female', 'Healthcare Disparities', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Regression Analysis', 'Risk Factors', 'Sex Distribution', 'Socioecono... | 28,394,964 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.060.406'], ['M0... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Are all the DNA gyrase mutations found in Mycobacterium leprae clinical strains involved in resistance to fluoroquinolones? | Mycobacterium leprae DNA gyrases carrying various mutations, previously described in clinical strains, were investigated for quinolone susceptibility by inhibition of supercoiling and DNA cleavage promotion. We demonstrated that the gyrA mutations leading to G89C or A91V confer fluoroquinolone resistance whereas the gy... | ['Anti-Infective Agents', 'DNA Gyrase', 'Drug Resistance, Bacterial', 'Fluoroquinolones', 'Humans', 'Microbial Sensitivity Tests', 'Mutation', 'Mycobacterium leprae'] | 18,070,975 | [['D27.505.954.122'], ['D08.811.399.403.741.149', 'D12.776.097.237'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['D03.633.100.810.835.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G05.365.590'], ['B03.510.024.962.500.502', 'B03.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patients with CD45 negative multiple myeloma receiving high-dose therapy have a shorter survival than those with CD45 positive multiple myeloma. | BACKGROUND AND OBJECTIVES: CD45 is a critical regulator of signaling threshold in immune cells. There are clinical and animal studies suggesting that the CD45-negative phenotype is the phenotype of progressive multiple myeloma (MM). The aims of this study were to confirm this hypothesis and to test the prognostic value... | ['Adult', 'Aged', 'Antineoplastic Agents, Alkylating', 'Bone Marrow Cells', 'Chromosomes, Human, Pair 14', 'Dose-Response Relationship, Drug', 'Female', 'Flow Cytometry', 'Humans', 'Immunophenotyping', 'Leukocyte Common Antigens', 'Male', 'Melphalan', 'Middle Aged', 'Multiple Myeloma', 'Plasma Cells', 'Prognosis', 'Ret... | 15,136,217 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['A11.148', 'A15.378.316'], ['A11.284.187.520.300.370.380', 'G05.360.162.520.300.370.380'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.24... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fine needle aspiration of splenic extramedullary hematopoiesis presenting as a solitary mass. A case report. | BACKGROUND: Extramedullary hematopoiesis (EMH) generally occurs in patients with deficient bone marrow hematopoiesis secondary to either peripheral red cell destruction or marrow replacement. EMH is most commonly seen in the liver and spleen as a diffuse lesion. Rarely EMH presents as a solitary mass, posing a diagnost... | ['Biopsy, Needle', 'Diagnosis, Differential', 'Hematopoiesis, Extramedullary', 'Humans', 'Male', 'Middle Aged', 'Spleen', 'Splenic Neoplasms', 'Tomography, X-Ray Computed'] | 12,462,096 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E01.171'], ['G04.152.825.463', 'G09.188.343.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A10.549.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Peripheral T-lymphocyte subpopulations in different clinical stages of chronic HBV infection correlate with HBV load. | AIM: To characterize the peripheral T-cell subpopulation profiles and their correlation with hepatitis B virus (HBV) replication in different clinical stages of chronic HBV infection.METHODS: A total of 422 patients with chronic HBV infection were enrolled in this study. The patients were divided into three stages: imm... | ['Adolescent', 'Adult', 'Biomarkers', 'DNA, Viral', 'Female', 'Hepatitis B', 'Hepatitis B virus', 'Humans', 'Male', 'Middle Aged', 'Regression Analysis', 'T-Lymphocyte Subsets', 'T-Lymphocytes', 'Viral Load', 'Young Adult'] | 19,610,139 | [['M01.060.057'], ['M01.060.116'], ['D23.101'], ['D13.444.308.568'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Kidney healing after laparoscopic partial nephrectomy without collecting system closure in pigs. | OBJECTIVES: To access the kidney healing after laparoscopic partial nephrectomy without closing of the collecting system in pigs.METHODS: Fourteen pigs underwent left partial laparoscopic nephrectomy, with removal of 25% of the kidney length at caudal pole (n = 7) or at cranial pole (n = 7). Briefly, the surgical techn... | ['Animals', 'Kidney', 'Kidney Tubules, Collecting', 'Laparoscopy', 'Male', 'Nephrectomy', 'Swine', 'Wound Healing'] | 21,109,297 | [['B01.050'], ['A05.810.453'], ['A05.810.453.736.560.510'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E04.950.774.435'], ['B01.050.150.900.649.313.500.880'], ['G16.762.891']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New sentence recognition materials developed using a basic non-native English lexicon. | PURPOSE: The objective of this project was to develop new sentence test materials drawing on a basic non-native English lexicon that could be used to test speech recognition for various listener populations. These materials have been designed to provide a test tool that is less linguistically biased, compared with mate... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Hearing Tests', 'Humans', 'Language', 'Linguistics', 'Male', 'Middle Aged', 'Noise', 'Speech Discrimination Tests', 'Speech Perception', 'Vocabulary', 'Young Adult'] | 22,411,279 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.382.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['L01.559.598'], ['M01.060.116.630'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['E01.370.382.375.060.060.750'], ['F02.463.593... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Tethered cord associated with anorectal malformation. | Ten children with a tethered cord and also an anorectal malformation are reported in this document. The anorectal malformations comprised 5 vesicointestinal fissures, 2 cloacal exstrophies, 2 rectovesical fistulas and 1 rectobulbar fistula. All of the patients underwent colostomy in advance of surgery for untethering o... | ['Abnormalities, Multiple', 'Adolescent', 'Anal Canal', 'Child', 'Child, Preschool', 'Colostomy', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Neural Tube Defects', 'Rectal Fistula', 'Rectum', 'Reoperation', 'Urinary Bladder Fistula'] | 12,566,840 | [['C16.131.077'], ['M01.060.057'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['M01.060.406'], ['M01.060.406.448'], ['E04.210.338.225', 'E04.579.338.225'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of dietary inclusion of toasted guar (Cyamopsis tetragonoloba) meal as a source of protein on performance of White Leghorn layers. | Two experiments were conducted to study the effect of including toasted (120°C/35 min) guar meal (GM, Cyamopsis tetragonoloba) in the diet on performance and egg shell quality of White Leghorn (WL) layers. Totals of 2376 and 2816 layer chickens (Babcock, BV 300) were randomly distributed into 27 and 32 replicates with ... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Chickens', 'Cyamopsis', 'Diet', 'Dietary Proteins', 'Dose-Response Relationship, Drug', 'Female', 'Ovum', 'Reproduction'] | 26,674,393 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.650.940.800.575.912.250.401.181'], ['G07.203.650.240'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.690.773.875', 'G07.690.936.500'], ['A05.360.490.690', 'A11... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[The role of transfusions in post-operative cytomegalovirus infections (in non-immunosuppressed subjects)]. | Cytomegalovirus (CMV) infection is most frequently observed after open heart surgery with extracorporeal circulation (ECC) and common after thoracic surgery without ECC and after splenectomies though very rare after other types of surgery. Studies on open heart patients with ECC carried out in the period 1968-1979 show... | ['Antibodies, Viral', 'Blood Preservation', 'Cardiac Surgical Procedures', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Extracorporeal Circulation', 'Humans', 'Immunosuppression', 'Postoperative Complications', 'Risk', 'Splenectomy', 'Transfusion Reaction', 'Virus Activation'] | 6,091,227 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E02.792.833.230', 'E05.760.833.230'], ['E04.100.376', 'E04.928.220'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['E04.292'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.450', 'E05.478.610'], ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fathers detained, contact restrained: Experiences of Palestinian children visiting their fathers in Israeli detention. | BACKGROUND: Very little is known about the experiences of children of political prisoners internationally, because of the challenges of researching within politically oppressive contexts.OBJECTIVE: The aim of this secondary analysis was to explore and understand Palestinian children's experiences visiting their fathers... | ['Adolescent', 'Arabs', 'Child', 'Child Advocacy', 'Child, Preschool', 'Father-Child Relations', 'Fathers', 'Female', 'Humans', 'Infant', 'Interviews as Topic', 'Israel', 'Male', 'Politics', 'Prisoners', 'Psychology, Child', 'Psychotherapy', 'Time Factors', 'United Nations', 'Young Adult'] | 31,400,603 | [['M01.060.057'], ['M01.686.754.167'], ['M01.060.406'], ['I01.880.604.473.300', 'I01.880.787.293.350', 'N03.706.437.300'], ['M01.060.406.448'], ['F01.829.263.370.290.110'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Molecular cloning of a complementary DNA encoding human macrophage-specific colony-stimulating factor (CSF-1). | Complementary DNA (cDNA) clones encoding human macrophage-specific specific colony-stimulating factor (CSF-1) were isolated. One cDNA clone codes for a mature polypeptide of 224 amino acids and a putative leader of 32 amino acids. This cDNA, which was cloned in the Okayama-Berg expression vector, specifies the synthesi... | ['Amino Acid Sequence', 'Base Sequence', 'Cell Line', 'Cloning, Molecular', 'Colony-Stimulating Factors', 'DNA', 'DNA Restriction Enzymes', 'Genes', 'Humans', 'Macrophages', 'Pancreatic Neoplasms', 'RNA, Messenger', 'Transcription, Genetic'] | 2,996,129 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['E05.393.220'], ['D12.644.276.374.410.240', 'D12.776.395.240', 'D12.776.467.374.410.240', 'D23.529.374.410.240'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Identifying controlling variables for math computation fluency through experimental analysis: the interaction of stimulus control and reinforcing consequences. | This study investigated a method for conducting experimental analyses of academic responding. In the experimental analyses, academic responding (math computation), rather than problem behavior, was reinforced across conditions. Two separate experimental analyses (one with fluent math computation problems and one with n... | ['Achievement', 'Child', 'Female', 'Humans', 'Mathematics', 'Problem Solving', 'Reinforcement, Psychology'] | 25,480,794 | [['F01.658.059', 'F02.784.629.054'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['F02.463.425.725', 'F02.463.785.810'], ['F02.463.425.770']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Osteochondral lesion of the fifth metatarsal head in a triathlete. | Osteochondral lesions (OCLs) are rare joint disorders, typically found in the larger joints of the body and less so in smaller joints (J Bone Joint Surg Am 41-A:988-1020, 1959; Arthroscopy 6(3):190-197, 1990; Clin Orthop Relat Res 148:245-253, 1980). Although their specific cause is subject to frequent debate, they are... | ['Adult', 'Anesthetics, Local', 'Athletic Injuries', 'Foot Injuries', 'Humans', 'Lidocaine', 'Magnetic Resonance Imaging', 'Male', 'Metatarsal Bones', 'Osteochondritis'] | 18,704,547 | [['M01.060.116'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['C26.115'], ['C26.558.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['E01.370.350.825.500'], ['A02.835.232.043.300.492'], ['C05.116.791', 'C05.182.520',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Platelet-to-Lymphocyte Ratio: A Novel Prognostic Factor for Prediction of 90-day Outcomes in Critically Ill Patients With Diabetic Ketoacidosis. | Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and the novel systemic inflammation marker platelet-to-lymphocyte ratio (PLR) may be associated with clinical outcome in patients with DKA. This study aimed to investigate the utility of PLR in predicting 90-day clinical outcomes ... | ['Adult', 'Aged', 'Critical Illness', 'Diabetic Ketoacidosis', 'Female', 'Humans', 'Intensive Care Units', 'Kaplan-Meier Estimate', 'Longitudinal Studies', 'Lymphocyte Count', 'Male', 'Middle Aged', 'Patient Readmission', 'Platelet Count', 'Predictive Value of Tests', 'Prognosis', 'Retrospective Studies', 'Time Factors... | 26,825,908 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.625'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['E05.318.372.500.750.500', 'N05.715.360... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Redioimmunoassay for secretin (author's transl)]. | The synthesis of a secretin with an elongated N-terminus, namely Nalpha-(deaminotyrosyl-beta-alanyl)- secretin (DATA-secretin), using a conventional strategy, is described. After purification of the product by means of ion exchange chromatography on SP-Sephadex C-25 and by continuous carrier-free electrophoresis, immun... | ['Animals', 'Antibody Formation', 'Methods', 'Rabbits', 'Radioimmunoassay', 'Secretin', 'Serum Albumin, Radio-Iodinated'] | 992,560 | [['B01.050'], ['G12.450.050.370.250'], ['E05.581'], ['B01.050.150.900.649.313.968.700'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['D06.472.317.800', 'D06.472.699.810', 'D12.644.400.705', 'D12.644.548.810', 'D12.776.631.650.705'], ['D12.776.034.841.603.500', 'D12.776.124.727.906.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding. | Two crystal structures of deamino-oxytocin have been determined at better than 1.1A resolution from isomorphous replacement and anomalous scattering x-ray measurements. In each of two crystal forms there are two closely related conformers with disulfide bridges of different chirality, which may be important in receptor... | ['Amino Acid Sequence', 'Dimethyl Sulfoxide', 'Hydrogen Bonding', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Oxytocin', 'Protein Conformation', 'Receptors, Angiotensin', 'Receptors, Cell Surface', 'Receptors, Oxytocin', 'X-Ray Diffraction'] | 3,008,332 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D02.886.640.150'], ['G02.282'], ['E05.196.867.519'], ['E05.599.595'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['G02.111.570.820.709'], ['D12.776.543.750.695.047', 'D12.776.543.750.750.130'], ['D12.776.543.750'], ['D12.776.543.750.695.630', 'D12.776.543.750.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Soluble guanylate cyclase stimulator BAY 41-8543 and female sex ameliorate uremic aortic remodeling in a rat model of mild uremia. | BACKGROUND: Cardiovascular disease is the leading comorbidity in renal patients and has been related to impaired nitric oxide signaling. Estrogens exert protective effects on the vascular system. This study investigates the effects of biological sex and nitric oxide-independent soluble guanylate cyclase (sGC) stimulato... | ['Animals', 'Aorta', 'Blood Pressure', 'Cell Proliferation', 'Female', 'Guanylate Cyclase', 'Kidney', 'Male', 'Matrix Metalloproteinase 2', 'Morpholines', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'Nitric Oxide', 'Nitric Oxide Synthase Type III', 'Pyrimidines', 'Rats', 'Rats, Wistar', 'Sex Factors', 'Signa... | 26,176,653 | [['B01.050'], ['A07.015.114.056'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['A05.810.453'], ['D08.811.277.656.300.480.205.352', 'D08.811.277.656.300.480.252.420', 'D08.811.277.656.300.480.525.700.150', 'D08.811.27... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Region 2.1 of the Escherichia coli heat-shock sigma factor RpoH (sigma32) is necessary but not sufficient for degradation by the FtsH protease. | The cellular level of the Escherichia coli heat-shock sigma factor RpoH (sigma32) is negatively controlled by chaperone-mediated proteolysis through the essential metalloprotease FtsH. Point mutations in the highly conserved region 2.1 stabilize RpoH in vivo. To assess the importance of this turnover element, hybrid pr... | ['ATP-Dependent Proteases', 'Bacterial Proteins', 'Bradyrhizobium', 'Escherichia coli', 'Escherichia coli Proteins', 'HSP40 Heat-Shock Proteins', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Protein Binding', 'Protein Structure, Tertiary', 'Recombinant Fusion Proteins', 'Sigma Factor'] | 17,660,420 | [['D08.811.277.040.013.500.032', 'D08.811.277.040.025.024.032', 'D08.811.277.656.149', 'D12.776.157.025.750.032'], ['D12.776.097'], ['B03.440.400.425.200.090', 'B03.660.050.035.090'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D12.776.580.216.292'], ['D12.776.580.216.375'], ['D12.776... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative Analysis of Secretome of Human Umbilical Cord- and Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells. | Production of cytokines and growth factors by cultured human umbilical cord tissue- and bone marrow-derived multipotent mesenchymal stromal cells was measured by multiplex analysis. In most cases, the concentrations of bioactive factors in the culture medium conditioned by umbilical cord-derived cells was ten- to hundr... | ['Bone Marrow Cells', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Female', 'Humans', 'Mesenchymal Stem Cells', 'Pregnancy', 'Umbilical Cord'] | 30,793,233 | [['A11.148', 'A15.378.316'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['G08.686.784.769'], ['A16.378.693']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunoprecipitation of A1 adenosine receptor-GTP-binding protein complexes in ciliary epithelial cells. | PURPOSE: To examine the interaction of alpha subunits of guanine nucleotide binding proteins with A1 adenosine receptors from the SV40-transformed bovine-derived pigmented (PE) and human-derived nonpigmented (NPE) ciliary epithelial cell lines using an immunoprecipitation approach and [3H]DPCPX, a selective radioligand... | ['Animals', 'Cattle', 'Cell Line', 'Cell Membrane', 'Cell Transformation, Viral', 'Cells, Cultured', 'Ciliary Body', 'GTP-Binding Proteins', 'Humans', 'Immunoglobulin G', 'Pigment Epithelium of Eye', 'Precipitin Tests', 'Radioligand Assay', 'Receptors, Purinergic P1', 'Simian virus 40', 'Theophylline'] | 8,206,723 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['A11.284.149'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['A11.251'], ['A09.371.060.160', 'A09.371.894.280'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diterpenoid fingerprints in pine foliage across an environmental and chemotypic matrix: Isoabienol content is a key trait differentiating chemotypes. | Diterpenoids constitute an important part of oleoresin in conifer needles, but the environmental and genetic controls on diterpenoid composition are poorly known. We studied the presence of diterpenoids in four pine populations spanning an extensive range of nitrogen (N) availability. In most samples, isoabienol was th... | ['Diterpenes', 'Molecular Conformation', 'Naphthols', 'Phenotype', 'Pinus'] | 29,304,384 | [['D02.455.849.291'], ['G02.111.570.820'], ['D02.455.426.559.847.638.638', 'D04.615.638.638'], ['G05.695'], ['B01.650.940.800.575.912.625.875.777']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The reproductive cycle in the male hedgehog (Erinaceus europaeus L.): a study of endocrine and exocrine testicular functions. | Seasonal changes in testicular and accessory gland weights, histological testicular structures, fructose and citric acid concentrations in two accessory glands and plasma testosterone levels were determined in adult male hedgehogs living in middle western France. Testicular activity started in winter (from December to ... | ['Animals', 'Dihydrotestosterone', 'Hedgehogs', 'Hibernation', 'Male', 'Reproduction', 'Seasons', 'Testis', 'Testosterone'] | 7,349,520 | [['B01.050'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['B01.050.150.900.649.313.961.376'], ['G07.110.232.889.500', 'G07.410.421.889.500', 'G16.012.500.535.889.500'], ['G08.686.784'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.31... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Occurrence of toxigenic cyanobacterial blooms in freshwaters of Sri Lanka. | A previous pioneering study of freshwater bodies in Sri Lanka revealed the presence of toxic cyanobacteria in three out of four water bodies tested. It was therefore important to perform a more detailed investigation into the presence of cyanobacteria and their toxins throughout Sri Lanka. The country has a long histor... | ['Bacterial Toxins', 'Cyanobacteria', 'Fresh Water', 'Microcystis', 'Plankton', 'Sri Lanka', 'Water Microbiology'] | 16,464,697 | [['D23.946.123'], ['B03.280', 'B03.440.475.100'], ['G16.500.275.280', 'N06.230.232'], ['B03.280.500', 'B03.440.475.100.500'], ['B05.080.500'], ['Z01.252.245.840', 'Z01.639.520.875'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Searching for the closest living relative(s) of tetrapods through evolutionary analyses of mitochondrial and nuclear data. | The phylogenetic relationships of the African lungfish (Protopterus dolloi) and the coelacanth (Latimeria chalumnae) with respect to tetrapods were analyzed using complete mitochondrial genome DNA sequences. A lungfish + coelancanth clade was favored by maximum parsimony (although this result is dependent on which tran... | ['Animals', 'DNA, Mitochondrial', 'Fishes', 'Lampreys', 'Phylogeny', 'Sequence Analysis, DNA'] | 10,766,578 | [['B01.050'], ['D13.444.308.283.225'], ['B01.050.150.900.493'], ['B01.050.150.900.493.559'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
CT angiography in highly calcified arteries: 2D manual vs. modified automated 3D approach to identify coronary stenoses. | BACKGROUND: Two-dimensional axial and manually-oriented reformatted images are traditionally used to analyze coronary data provided by multidetector-row computed tomography angiography (MDCTA). While apparently more accurate in evaluating calcified vessels, 2D methods are time-consuming compared with automated 3D appro... | ['Adult', 'Aged', 'Aged, 80 and over', 'Calcinosis', 'Coronary Angiography', 'Coronary Stenosis', 'Coronary Vessels', 'Feasibility Studies', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Radiographic Image Interpretation, Computer-Assisted', 'Time Factors', 'Tomo... | 16,538,435 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C18.452.174.130'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['A07.015.114.269', 'A07.015.908.194'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Utility of real-time video teleconferencing in conducting family mental health sessions: two case reports. | Due to the worldwide mission of the military, service members often find themselves isolated from their families and other important people in their lives. Historically, this has been especially problematic during periods of illness, as the isolation has precluded the meaningful involvement of families in patient care.... | ['Adult', 'Family Therapy', 'Hawaii', 'Hospitals, Military', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Military Medicine', 'Telemedicine'] | 11,321,710 | [['M01.060.116'], ['F04.754.864.581.273'], ['Z01.107.567.875.580.375', 'Z01.639.760.815.482'], ['N02.278.421.510.180.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['H02.403.500'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Prevalence of a gluten-free diet and improvement of clinical symptoms in patients with inflammatory bowel diseases. | BACKGROUND: Maintaining a gluten-free diet (GFD) without an underlying diagnosis of celiac disease has enjoyed widespread acceptance in the Unites States.METHODS: We performed a cross-sectional study using a GFD questionnaire in 1647 patients with inflammatory bowel diseases (IBD) participating in the CCFA Partners lon... | ['Adult', 'Celiac Disease', 'Chi-Square Distribution', 'Colitis, Ulcerative', 'Crohn Disease', 'Cross-Sectional Studies', 'Diet, Gluten-Free', 'Female', 'Follow-Up Studies', 'Humans', 'Inflammatory Bowel Diseases', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Prevalence', 'Risk Assessment', 'Severity of Illness Inde... | 24,865,778 | [['M01.060.116'], ['C06.405.469.637.250', 'C18.452.603.250'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E05.318.372.500.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure-function analyses of a caffeic acid O-methyltransferase from perennial ryegrass reveal the molecular basis for substrate preference. | Lignin forms from the polymerization of phenylpropanoid-derived building blocks (the monolignols), whose modification through hydroxylation and O-methylation modulates the chemical and physical properties of the lignin polymer. The enzyme caffeic acid O-methyltransferase (COMT) is central to lignin biosynthesis. It is ... | ['Catalytic Domain', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Kinetics', 'Lolium', 'Methyltransferases', 'Models, Molecular', 'Structure-Activity Relationship', 'Substrate Specificity'] | 21,177,481 | [['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309.742.225'], ['G02.282'], ['G01.374.661', 'G02.111.490'], ['B01.650.940.800.575.912.250.822.500'], ['D08.811.913.555.500'], ['E05.599.595'], ['G02.111.830', 'G07.690.773.997'], ['G02.111.835']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Valve Heart Surgery in Brazil - The BYPASS Registry Analysis. | OBJECTIVE: To analyze the profile and outcomes of patients who underwent valve heart surgery in Brazil, using information retrieved from the Brazilian Registry of Cardiovascular Surgeries in Adults (BYPASS Registry) database.METHODS: This is a multicenter cohort study, evaluating 920 patients submitted to heart valve s... | ['Adult', 'Aged', 'Brazil', 'Cardiac Surgical Procedures', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Registries', 'Retrospective Studies', 'Treatment Outcome'] | 32,270,964 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.757.176'], ['E04.100.376', 'E04.928.220'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.70... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of time on dialysis and renal transplantation on endothelial function: a longitudinal analysis. | BACKGROUND: Soluble vascular cell adhesion molecule-1 (sVCAM-1) is a marker of endothelial injury and a potent predictor of cardiovascular mortality in patients with kidney failure on dialysis. The longitudinal effects of dialysis on endothelial dysfunction and in particular the effects of renal transplantation on mark... | ['Adult', 'Biomarkers', 'Cardiovascular Diseases', 'Cohort Studies', 'Endothelium, Vascular', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Renal Dialysis', 'Retrospective Studies', 'Time Factors', 'Vascular Cell Adhesion Molecule-1'] | 24,879,381 | [['M01.060.116'], ['D23.101'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regulation of rat mesangial cell migration by platelet-derived growth factor, angiotensin II, and adrenomedullin. | This study sought to determine whether platelet-derived growth factor (PDGF) and angiotensin II (AngII) stimulate migration of cultured rat glomerular mesangial cells. After finding that this was so, the effects of adrenomedullin (ADM) and cAMP-elevating agents on basal and stimulated mesangial cell migration were exam... | ['8-Bromo Cyclic Adenosine Monophosphate', 'Adrenomedullin', 'Angiotensin II', 'Animals', 'Becaplermin', 'Calcitonin Gene-Related Peptide', 'Cell Adhesion', 'Cell Movement', 'Cells, Cultured', 'Colforsin', 'Cyclic AMP', 'Cyclic AMP-Dependent Protein Kinases', 'Enzyme Inhibitors', 'Epoprostenol', 'Glomerular Mesangium',... | 10,589,687 | [['D03.633.100.759.646.138.395.225', 'D13.695.462.200.225', 'D13.695.667.138.395.225', 'D13.695.827.068.395.225'], ['D06.472.699.077', 'D12.644.548.017'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['D12.64... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a new vaccine for the prevention of Lassa fever. | BACKGROUND: Recent importation of Lassa fever into Germany, the Netherlands, the United Kingdom, and the United States by travelers on commercial airlines from Africa underscores the public health challenge of emerging viruses. Currently, there are no licensed vaccines for Lassa fever, and no experimental vaccine has c... | ['Animals', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Lassa Fever', 'Lassa virus', 'Macaca fascicularis', 'Vaccination', 'Vaccines, Synthetic', 'Viral Vaccines', 'Viremia'] | 15,971,954 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.290.750', 'E05.337.550'], ['C01.925.782.082.545', 'C01.925.782.417.505'], ['B04.820.480.500.070.100.500'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', 'N02.421.726.758.310.890', 'N06.85... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Lentinan-graft-polyethylenimine-a novel vector for gene delivery]. | OBJECTIVE: To develop a novel vector for gene delivery with low molecular weight polyethylenimine grafted to the natural polysaccharide and conjugated to folic acid (LNT-PEI-FA).METHODS: The properties of LNT-PEI-FA were characterized by (1)H-NMR, FT-IR and TGA, respectively. The particle size of LNT-PEI-FA/DNA complex... | ['Cell Line', 'Folic Acid', 'Gene Transfer Techniques', 'Genetic Therapy', 'Humans', 'Lentinan', 'Polyethyleneimine'] | 19,253,427 | [['A11.251.210'], ['D03.633.100.733.631.400'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.365.089.500'], ['D02.455.326.271.665.550.600', 'D02.491.650', 'D05.750.716.507.600', 'D25.720.716.507.600', 'J01.637.051.720.716.507.600']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Design of Treatment System for Poor Peripheral Circulation Using Air Wave Pressure Based on STM32 Microprocessor]. | This study designs an intermittent pneumatic pressurization device with STM32 series single chip as the core. The working state of the air pump and the plurality of air chambers is controlled by the IO port of the single chip microcomputer, and the circulating inflation of the plurality of air bags is realized. The pre... | ['Blood Circulation', 'Cardiovascular System', 'Equipment Design', 'Humans', 'Microcomputers', 'Pressure'] | 32,343,065 | [['G09.330.100'], ['A07'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.260.550'], ['G01.374.715']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Population structure and transmission modes of indigenous typhoid in Taiwan. | BACKGROUND: Indigenous typhoid fever was continuing to be identified in Taiwan which has not been endemic for the enteric fever for more than 20 years. The source and transmission by which the local patients acquired typhoid and the population structure of the indigenous typhoid strains remain not well characterized.ME... | ['Anti-Bacterial Agents', 'Demography', 'Disease Outbreaks', 'Genome, Human', 'Humans', 'Phylogeny', 'Population Dynamics', 'Salmonella typhi', 'Taiwan', 'Typhoid Fever', 'Whole Genome Sequencing'] | 31,481,113 | [['D27.505.954.122.085'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['N06.850.290'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['B03.440.450.425.800.200.800', 'B03.660.250.150.710.160.750'], ['... | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Blood lactate accumulation during exercise in older endurance runners. | To delineate the possible age-related differences in blood lactate response during exercise and its relations to endurance performance, 34 male runners (aged 21 to 69 years) performed an incremental treadmill running test. There were no significant differences in training distance and relative body fat among younger ru... | ['Adult', 'Aged', 'Aging', 'Exercise', 'Humans', 'Lactates', 'Male', 'Middle Aged', 'Oxygen Consumption', 'Physical Endurance', 'Running'] | 3,182,154 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459'], ['M01.060.116.630'], ['G03.680'], ['G11.427.680', 'I03.450.642.845.054.600'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.8... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
A limited sampling strategy for the estimation of Neoral AUCs in pediatric patients. | The improved pharmacokinetics of Neoral allows the development of an accurate estimate of the full area under the concentration time curve (AUC) from a limited sampling strategy. As no such strategy has been derived from pharmacokinetic data obtained from children on 12-hourly dosing, and as patient convenience demands... | ['Adolescent', 'Adult', 'Area Under Curve', 'Child', 'Child, Preschool', 'Cyclosporine', 'Female', 'Humans', 'Immunosuppressive Agents', 'Kidney Transplantation', 'Linear Models', 'Male'] | 10,603,112 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['M01.060.406'], ['M01.060.406.448'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Studies on the role of uncharged tRNA in pleiotypic response of animal cells. | Experiments were carried out to assess the physiological significance of the charging level of tRNA. Histidinol, a competitve inhibitor of charging of tRNAHis, was used to induce uncharged tRNA in mammalian cells. It is demonstrated that both in the presence of histidinol and under histidine depletion about 40% of the ... | ['Animals', 'Biological Transport, Active', 'Calcium', 'Carcinoma, Ehrlich Tumor', 'Cell Line', 'Cell Nucleolus', 'Cell Nucleus', 'Histidine', 'Histidinol', 'Kinetics', 'Mice', 'RNA, Transfer', 'Ribonucleotides'] | 1,278,158 | [['B01.050'], ['G03.143.310'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C04.557.470.200.200', 'C04.619.169'], ['A11.251.210'], ['A11.284.430.106.279.345.175'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D12.125.072.329', 'D12.125.142.308'], ['D02.033.100.624.380', 'D02.033.755.624.380', 'D02.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of pipradrol on the acquisitionof responding with conditioned reinforcement: a role for sensory preconditioning. | Previous studies have shown that pipradrol enhances the acquisition of responding with conditioned reinforcement. The present experiments replicated this finding and assessed the possible role of nonspecific stimulus change, feeding in the test environment and prior exposure to the conditioned stimulus. The test proced... | ['Acoustic Stimulation', 'Animals', 'Conditioning, Operant', 'Food', 'Male', 'Piperidines', 'Rats', 'Reinforcement, Psychology'] | 6,106,257 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictors of Career Choice Among Cardiothoracic Surgery Trainees. | BACKGROUND: The impact of factors influencing career choice by cardiothoracic surgery (CTS) trainees remains poorly defined in the modern era. We sought to examine the associations between CTS trainee characteristics and future career aspirations.METHODS: The 2012 Thoracic Surgery In-Training Examination survey results... | ['Career Choice', 'Forecasting', 'Surveys and Questionnaires', 'Thoracic Surgery'] | 26,163,358 | [['F02.463.785.373.346.400'], ['I01.320'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['H02.403.810.803']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Changes in plasma calcium during septic shock. | Previous studies have documented a decrease in plasma calcium occurring early after trauma, haemorrhage and cardiac arrest. Therefore, changes in plasma calcium in an ovine experimental model of septic shock due to intraperitoneal sepsis were investigated. Subjects were volume-loaded with Ringer's lactate solution. Pla... | ['Animals', 'Calcium', 'Disease Models, Animal', 'Hemodynamics', 'Serum Albumin', 'Sheep', 'Shock, Septic'] | 7,921,547 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G09.330.380'], ['D12.776.034.841', 'D12.776.124.727'], ['B01.050.150.900.649.313.500.380.791'], ['C01.757.800', 'C23.550.470.790.500.800', 'C23.550.835.900.712']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Urinary catecholamine excretion and cardiac output in hypertensive patients]. | Cardiac output was determined to 70 patients with hypertonic disease I, II and III stage by dye-dilution method and urine excretion of adrenaline and noradrenaline was determined by fluorescence method. The extent of stroke and minute volume was determined depending on the stage of the disease, degree of arterial hyper... | ['Adult', 'Age Factors', 'Cardiac Output', 'Epinephrine', 'Female', 'Heart Rate', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Norepinephrine', 'Sex Factors', 'Stroke Volume'] | 7,101,894 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.370.380.150', 'G09.330.380.124'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does the plasma application time affect the tensile bond strength between PMMA and a silicone-based denture liner? | Aims: This study evaluated the effect of oxygen plasma and argon plasma treatments with different application times on tensile bonding of a silicone-based denture liner to polymethylmetacrylate (PMMA).Methods: Seven groups (n = 5) were prepared and six of them treated by argon plasma or oxygen plasma with 30s, 60s, and... | ['Argon', 'Argon Plasma Coagulation', 'Dental Bonding', 'Denture Bases', 'Denture Liners', 'Humans', 'Materials Testing', 'Oxygen', 'Polymethyl Methacrylate', 'Silicones', 'Surface Properties', 'Tensile Strength'] | 32,913,167 | [['D01.268.613.050', 'D01.362.641.113'], ['E02.154.402.054', 'E02.520.089', 'E04.014.170.402.054', 'E04.350.500'], ['E06.095'], ['E06.780.346.760.281', 'E07.695.190.200.200'], ['E06.780.346.760.357', 'E07.695.190.200.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['D01.268.185.550', 'D01.362.670']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat. | We have compared the relative importance of transcription regulatory regions in the U3 and R regions of the human immunodeficiency virus type 1 long terminal repeat (LTR) by using linker-scanning mutational analysis. Twenty-six mutant LTR-chloramphenicol acetyltransferase (CAT) transient expression plasmids were prepar... | ['Base Sequence', 'Binding Sites', 'Cell Line', 'Chromosome Deletion', 'Cloning, Molecular', 'DNA, Viral', 'HIV Long Terminal Repeat', 'Humans', 'Molecular Sequence Data', 'NF-kappa B', 'Plasmids', 'Restriction Mapping', 'Sp1 Transcription Factor', 'TATA Box', 'Transcription, Genetic', 'Transfection'] | 2,016,766 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.251.210'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['E05.393.220'], ['D13.444.308.568'], ['G02.111.570.080.708.850.400', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A quantitative MRI study of posterior fossa development in velocardiofacial syndrome. | BACKGROUND: Velocardiofacial syndrome (VCFS) has been identified as a risk factor for developing schizophrenia. Qualitative neuroimaging studies indicated that VCFS was frequently associated with abnormal development of structures in the posterior fossa of the brain. The objective of this investigation was to identify ... | ['Abnormalities, Multiple', 'Adolescent', 'Brain', 'Child', 'Child Behavior Disorders', 'Cognition Disorders', 'Cranial Fossa, Posterior', 'Face', 'Female', 'Heart Defects, Congenital', 'Humans', 'Learning Disabilities', 'Magnetic Resonance Imaging', 'Male', 'Severity of Illness Index', 'Syndrome', 'Velopharyngeal Insu... | 11,257,239 | [['C16.131.077'], ['M01.060.057'], ['A08.186.211'], ['M01.060.406'], ['F03.625.141'], ['F03.615.250'], ['A01.456.830.200', 'A02.835.232.781.750.400'], ['A01.456.505'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', '... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Conjugation transfer of the pAMbeta1 plasmid to Bacillus anthracis]. | The possibility of conjugational transfer of the plasmid pAM beta 1 in the cells of different strains of Bacillus anthracis has been established. The efficiency of the plasmid replicon transfer in interspecies transfer B. thuringiensis X B. anthracis was n.10(-7), while in interspecies transfer it was n.10(-6). The cap... | ['Bacillus anthracis', 'Conjugation, Genetic', 'DNA, Bacterial', 'Plasmids'] | 2,114,531 | [['B03.300.390.400.158.218.151', 'B03.353.500.100.218.151', 'B03.510.100.100.218.151', 'B03.510.415.400.158.218.151', 'B03.510.460.410.158.218.151'], ['G05.728.200'], ['D13.444.308.212'], ['G05.360.600']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Treatments and diagnosis of lung cancer--field study results: report from japan lung cancer TNM classification committee]. | The results of 4,931 lung cancer cases treated during 1970-72 were examined to evaluate the factors (especially N factors) influencing the prognosis of lung cancer. The background factors examined included T-factor, N-factor, M-factor, clinical stage, histological type, age and sex. The prognosis was also examined acco... | ['Adenocarcinoma', 'Aged', 'Carcinoma, Squamous Cell', 'Female', 'Humans', 'Japan', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Prognosis', 'Smoking'] | 6,881,994 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E01.789'], ['F01.1... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[Augmented posterior instrumentation for the treatment of osteoporotic vertebral body fractures]. | OBJECTIVE: Reduction and stabilization of osteoporotic vertebral body fractures using posterior short-segment instrumentation. Cement augmentation of the pedicle screws in order to improve the screw’s holding power in osteoporotic bone and to reduce postoperative loss of reduction. Quick and painless postoperative mobi... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bone Cements', 'Bone Screws', 'Female', 'Follow-Up Studies', 'Humans', 'Kyphoplasty', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Osteoporotic Fractures', 'Patient Positioning', 'Polymethyl Methacrylate', 'Postoperative Complications', 'Radiography', 'Spinal Fractures', 'Spinal F... | 22,297,474 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Preliminary observations on lungworms in farmed and feral red deer (Cervus elaphus) in Denmark. | Deer farming is on its increase in Denmark. Based on experiences from other countries, lungworm infection is expected to cause severe problems in farmed deer. Therefore, in the present paper, which is the first one to deal with pathogens in Danish deer farms, the faecal larval excretion in red deer is examined. | ['Animals', 'Animals, Domestic', 'Animals, Wild', 'Cattle', 'Deer', 'Denmark', 'Dictyocaulus Infections', 'Feces', 'Female', 'Lung Diseases, Parasitic', 'Male', 'Nematode Infections', 'Strongyloidea'] | 2,944,072 | [['B01.050'], ['B01.050.050.116'], ['B01.050.050.300'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.649.313.500.380.373'], ['Z01.542.816.124'], ['C01.610.335.349.315', 'C01.610.335.508.700.775.825.315', 'C01.610.701.377.315', 'C22.674.377.315'], ['A12.459'], ['C01.610.582', 'C01.748.450', 'C08.381.517', ... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Astrocyte-conditioned medium stimulates HIV-1 expression in a chronically infected promonocyte clone. | Human promonocytic cells chronically infected with human immunodeficiency virus-1 (HIV-1) (clone U1.1.5) were grown in the presence of media conditioned by primary rat cortical astrocytes and HIV-1 expression was assessed by measuring reverse transcriptase activity. Media conditioned by non-stimulated and lipopolysacch... | ['Animals', 'Astrocytes', 'Culture Media', 'HIV-1', 'Humans', 'Lipopolysaccharides', 'Monocytes', 'Rats', 'Recombinant Proteins', 'Tumor Necrosis Factor-alpha', 'Virus Activation'] | 2,229,407 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['D27.720.470.305', 'E07.206'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A11.118.637.555.652', 'A11.148.580', 'A11.627.624', 'A11.733.547'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multivariate analysis of factors predicting local relapse after radical prostatectomy--possible indications for postoperative radiotherapy. | Between 1970 and 1983, 273 patients underwent radical surgery (radical prostatectomy--261, radical cystoprostatectomy--12) for newly diagnosed adenocarcinoma of the prostate at Duke University Medical Center and received no adjuvant radiotherapy. A total of 46 patients developed local recurrence. Forty developed local ... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Recurrence, Local', 'Prognosis', 'Prostatectomy', 'Prostatic Neoplasms', 'Retrospective Studies', 'Risk Factors'] | 1,917,623 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.15... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of antibodies by enzyme-immunoassay in human schistosoma mansoni infections: a clinical and chemotherapeutic study. | Sera from patients with S. mansoni infections, before and six weeks after successful treatment with hycanthone, were examined for antibodies reacting with S. mansoni adult worm antigen, employing the enzyme-linked immunosorbent assay (ELISA) technique. 50 local individuals who had no schistosomiasis and 48 patients wit... | ['Adult', 'Antibodies', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Follow-Up Studies', 'Humans', 'Hycanthone', 'Male', 'Schistosoma haematobium', 'Schistosoma mansoni', 'Schistosomiasis'] | 741,502 | [['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dysarthria in Friedreich's ataxia: a perceptual analysis. | The aims of this study were to: (1) evaluate the perceptual speech dimensions, speech intelligibility and dysarthria severity of a group of individuals diagnosed with Friedreich's ataxia (FRDA); (2) determine the presence of subgroups within FRDA dysarthria; (3) investigate the relationship between the speech outcome a... | ['Adult', 'Cerebellum', 'Cluster Analysis', 'Disease Progression', 'Dysarthria', 'Female', 'Friedreich Ataxia', 'Humans', 'Larynx', 'Male', 'Middle Aged', 'Observer Variation', 'Pharyngeal Muscles', 'Severity of Illness Index', 'Speech Intelligibility', 'Speech Production Measurement', 'Trinucleotide Repeats', 'Velopha... | 20,424,464 | [['M01.060.116'], ['A08.186.211.132.810.428.200'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['C23.550.291.656'], ['C10.597.606.150.500.800.150.200', 'C23.888.592.604.150.500.800.150.200'], ['C10.228.140.252.700.150', 'C10.228.854.787.200', 'C10.574.500.825.200', 'C16.320.400.780.200', 'C18.452... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of 2 femoral tunnel locations in anatomic single-bundle anterior cruciate ligament reconstruction: a biomechanical study. | PURPOSE: To evaluate knee stability after anterior cruciate ligament (ACL) reconstruction using 2 modern clinically relevant single-bundle constructs.METHODS: Two arthroscopic ACL reconstructions were performed on 6 fresh-frozen human cadaveric knees using bone-patellar tendon-bone autografts. The tibial tunnel was cen... | ['Adult', 'Aged', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Reconstruction', 'Biomechanical Phenomena', 'Bone-Patellar Tendon-Bone Grafting', 'Cadaver', 'Femur', 'Humans', 'Joint Instability', 'Knee Joint', 'Middle Aged', 'Rotation', 'Tibia'] | 22,796,141 | [['M01.060.116'], ['M01.060.116.100'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['E04.555.110.026', 'E04.680.101.026'], ['G01.154.090', 'G01.374.089'], ['E02.095.147.725.065', 'E04.555.110.026.500', 'E04.680.101.026.500', 'E04.936.580.065'], ['C23.550.260.224'], ['A02.835.232.043.150'], ['B01.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Left hepatic vein injury during laparoscopic fundoplication for giant paraoesophageal hiatal hernia]. | INTRODUCTION: After laparoscopic cholecystectomy, laparoscopic fundoplication has become another gold standard of minimal invasive surgery. The level of satisfaction of patients undergoing endoscopic surgery is almost 90%. Laparoscopic fundoplication, like other surgery methods, can also be burdened with grave complica... | ['Fundoplication', 'Gastroesophageal Reflux', 'Hepatic Veins', 'Hernia, Hiatal', 'Humans', 'Laparoscopy'] | 28,433,047 | [['E04.210.390'], ['C06.405.117.119.500.484'], ['A07.015.908.380'], ['C23.300.707.960.500.467'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
AIDS fears and homophobia among rural nursing personnel. | Attitudes and concerns about AIDS of 144 nursing personnel attending conferences on AIDS in rural central Pennsylvania were assessed. Participants were knowledgeable about AIDS but wished to learn more and wanted additional training. Most were moderately worried about contracting AIDS, and a sizeable percentage showed ... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Aged', 'Attitude of Health Personnel', 'Fear', 'Female', 'Homosexuality', 'Humans', 'Male', 'Middle Aged', 'Nurses', 'Pennsylvania', 'Rural Population'] | 2,641,251 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['F01.470.361'], ['F01.145.802.975.500', 'G08.686.867.500'], ['B01.050.150.900.649... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Longitudinal course of panic disorder with and without agoraphobia using the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). | Few naturalistic, longitudinal studies of panic disorder with and without agoraphobia (PD/PDA) exist, limiting our knowledge of the temporal rates of incidence, relapse, and chronicity, or the factors that predict category transition. Data from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC... | ['Adolescent', 'Adult', 'Agoraphobia', 'Chronic Disease', 'Disease Progression', 'Female', 'Health Surveys', 'Humans', 'Incidence', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Panic Disorder', 'Recurrence', 'Risk Factors', 'United States'] | 23,587,657 | [['M01.060.057'], ['M01.060.116'], ['F03.080.100'], ['C23.550.291.500'], ['C23.550.291.656'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A maturation model for midazolam clearance. | BACKGROUND: Physiological-based pharmacokinetic models have been used to describe midazolam clearance (CL) maturation. There are no maturation descriptors of CL from neonate to adulthood based on reported estimates at different ages.METHODS: Published CL estimates after intravenous administration from time-concentratio... | ['Adolescent', 'Aging', 'Algorithms', 'Body Weight', 'Child', 'Child, Preschool', 'Female', 'Half-Life', 'Humans', 'Hypnotics and Sedatives', 'Infant', 'Infant, Newborn', 'Infusions, Intravenous', 'Injections, Intravenous', 'Male', 'Midazolam', 'Models, Statistical', 'Nonlinear Dynamics', 'Pregnancy'] | 20,704,661 | [['M01.060.057'], ['G07.345.124'], ['G17.035', 'L01.224.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['M01.060.406.448'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
The effect of food or milk on the bioavailability of etintidine in healthy subjects. | A three-way crossover study was conducted in 24 normal, male volunteers to compare the bioavailability of etintidine from capsules (2 X 200 mg) taken under fasting conditions, with food and with milk. Blood samples were collected prior to and at various times after each treatment and plasma levels of etintidine were de... | ['Adolescent', 'Adult', 'Animals', 'Biological Availability', 'Food', 'Histamine H2 Antagonists', 'Humans', 'Imidazoles', 'Male', 'Milk'] | 2,900,817 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['G07.203.300', 'J02.500'], ['D27.505.519.625.375.425.425', 'D27.505.696.577.375.425.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics. | Mitomycin C (MC) is a naturally occurring anticancer agent which has been shown to be more cytotoxic to hypoxic tumor cells than to their aerobic counterparts. The mechanism of action of this agent is thought to involve biological reductive activation, to a species that alkylates DNA. A comparison of the cytotoxicity o... | ['Animals', 'Antibiotics, Antineoplastic', 'Biotransformation', 'Cattle', 'Cell Line', 'Cell Survival', 'Female', 'Free Radicals', 'Hydroxides', 'Mammary Neoplasms, Experimental', 'Mice', 'Mitochondria, Heart', 'Mitomycins', 'Oxygen', 'Oxygen Consumption', 'Structure-Activity Relationship', 'Superoxides', 'Xanthine Oxi... | 3,011,250 | [['B01.050'], ['D27.505.954.248.106'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['G04.346'], ['D01.339', 'D02.389'], ['D01.045.250', 'D01.248.497.158.459'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microscopic emphysema in relation to age and smoking habit. | BACKGROUND: The increases in airspace size within the human lung associated with microscopic emphysema can be assessed by measuring the airspace wall surface area per unit volume of lung tissue (AWUV). In a previous study the limits of normality of AWUV with age were estimated in lifelong non-smokers by the 95% predict... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Disease Susceptibility', 'Female', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Pulmonary Emphysema', 'Smoking'] | 8,322,234 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['C23.550.291.687', 'G07.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ['C08.381.495.389.750'], ['F01.145.805']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Causes of death among persons diagnosed with hepatitis C infection in the pre- and post-DAA era in England: A record linkage study. | Through record linkage, we describe the causes of death among persons with diagnosis of hepatitis C virus (HCV) in England. Persons ?1 year with anti-HCV/HCV-PCR tests reported to PHE sentinel surveillance during 2002-2016 were linked to death registrations from the Office for National Statistics during 2008-2016. We f... | ['Aged', 'Cause of Death', 'Coinfection', 'Comorbidity', 'England', 'Female', 'HIV Infections', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Male', 'Middle Aged', 'Public Health Surveillance'] | 30,896,055 | [['M01.060.116.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C01.218'], ['N05.715.350.225', 'N06.850.490.687'], ['Z01.542.363.300'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Embovin efficacy and tolerance in the treatment of patients with intestinal nematode infections]. | The efficacy and tolerance of embovin, a new anthelminthic manufactured in Russia, was studied in 60 patients with nematodiases. The results evidence its high efficacy in ankylostomiasis (100%), enterobiasis (100%), and ascariasis (90 +/- 6.4%). The drug was well tolerated in all the cases. No adverse effects on the li... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Drug Tolerance', 'Female', 'Humans', 'Intestinal Diseases, Parasitic', 'Male', 'Nematode Infections', 'Pyrantel Pamoate'] | 8,028,558 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['G07.690.773.992'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.432', 'C06.405.469.452'], ['C01.610.335.508'], ['D02.886.778.634.600', 'D03.383.742.634.600', 'D03.383.903.634.600']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fatty acid metabolism in sn-glycerol-3-phosphate acyltransferase (plsB) mutants. | Fatty acid metabolism was examined in Escherichia coli plsB mutants that were conditionally defective in sn-glycerol-3-phosphate acyltransferase activity. The fatty acids synthesized when acyl transfer to glycerol-3-phosphate was inhibited were preferentially transferred to phosphatidylglycerol. A comparison of the rat... | ['Acyl Coenzyme A', 'Acyltransferases', 'Escherichia coli', 'Fatty Acids', 'Genotype', 'Glycerol-3-Phosphate O-Acyltransferase', 'Mutation', 'Phospholipids'] | 3,542,964 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['D08.811.913.050'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D10.251'], ['G05.380'], ['D08.811.913.050.425'], ['G05.365.590'], ['D10.570.755']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue. | Loop-mediated isothermal amplification (LAMP), a novel gene amplification method, enables the synthesis of larger amounts of both DNA and a visible byproduct--namely, magnesium pyrophosphate--without thermal cycling. A positive reaction is indicated by the turbidity of the reaction solution or the color change after ad... | ['Colorimetry', 'Coloring Agents', 'DNA', 'Naphthalenesulfonates', 'Naphthols', 'Nucleic Acid Amplification Techniques', 'RNA'] | 19,317,660 | [['E05.196.922.250'], ['D27.720.233'], ['D13.444.308'], ['D02.455.426.559.847.638.555', 'D02.886.645.600.080.050.650', 'D04.615.638.555'], ['D02.455.426.559.847.638.638', 'D04.615.638.638'], ['E05.393.620'], ['D13.444.735']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of Urine Reagent Strip as a Tool for Routine Diagnosis of Maternal Urogenital Schistosomiasis at Antenatal Clinic Visit in Munyenge, South West Region, Cameroon. | Urine reagent strip used in detecting microhaematuria has been recommended in pregnancy for diagnosis of urogenital schistosomiasis (UGS) during routine antenatal care (ANC). This study evaluated its sensitivity, specificity, and predictive values in the diagnosis of maternal UGS using filtration method as a reference ... | ['Adult', 'Ambulatory Care', 'Ambulatory Care Facilities', 'Animals', 'Female', 'Hematuria', 'Humans', 'Physical Examination', 'Pregnancy', 'Prenatal Diagnosis', 'Proteinuria', 'Reagent Strips', 'Schistosoma haematobium', 'Schistosomiasis haematobia'] | 31,886,198 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['N02.278.035'], ['B01.050'], ['C12.777.934.442', 'C13.351.968.934.442', 'C23.550.414.849'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600'], ['G08.686.784.769'], ['E01.370.378.630'], ['C12.777.934.734', 'C13.351.968.934.734', 'C23.888.942.750'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effective measuring point of ion chambers for photon dosimetry in phantoms. | The effective point of measurement for spherical ionization chambers has been determined for 60Co and 137Cs gamma rays and for 300 kV X rays inside a water phantom. For reasons of comparison, measurements were also performed with a thimble-type Baldwin-Farmer ion chamber. For spherical ion chambers the displacement cor... | ['Elementary Particles', 'Gamma Rays', 'Models, Structural', 'Radiation Dosage', 'Radiometry', 'Scattering, Radiation', 'X-Rays'] | 7,426,870 | [['G01.249'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05.799'], ['E05.196.822', 'G01.867'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Usefulness of serum C-reactive protein level for predicting flap complication after performing free microvascular head and neck reconstruction. | BACKGROUND: Free microvascular head and neck reconstruction requires minimal complication and safety. However, clinical observation of the wound in head and neck area is very difficult because of its narrow and inaccessible anatomy. Serum C-reactive protein (CRP) level is commonly used as a marker of acute inflammatory... | ['Adult', 'Aged', 'Biomarkers', 'C-Reactive Protein', 'Female', 'Free Tissue Flaps', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Microsurgery', 'Middle Aged', 'Necrosis', 'Postoperative Complications', 'Predictive Value of Tests', 'Reconstructive Surgical Procedures', 'Retrospective Studies'] | 24,892,417 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['A10.850.710.500', 'E07.862.710.500'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.494', 'E05.591.580'], ['M01.060.116.630'], ['C23.550.717'], ['C23.550.767'], ['E05.318.37... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pefloxacin in lower respiratory tract infections. | To determine the efficacy and safety of pefloxacin in the treatment of lower respiratory tract infections, a multicentre trial involving four departments of respiratory diseases was performed. One hundred and eight patients were admitted to the study: most of them were affected with exacerbations of chronic bronchitis ... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bronchitis', 'Bronchopneumonia', 'Chronic Disease', 'Female', 'Humans', 'Injections, Intravenous', 'Male', 'Middle Aged', 'Pefloxacin', 'Pleurisy', 'Pneumonia'] | 2,258,337 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['C01.748.610.127', 'C08.127.509', 'C08.381.677.127', 'C08.730.610.127'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Independent effects of geometry and landmark in a spontaneous reorientation task: a study of two species of fish. | While disoriented humans and animals use both landmarks and environmental geometry to guide their navigation, it is not clear what kinds of cognitive mechanisms underlie these behaviors. Because traditional tests of trained navigation behavior in environments containing both landmarks and geometric information may clou... | ['Animals', 'Cyprinodontiformes', 'Environment', 'Female', 'Male', 'Orientation', 'Pattern Recognition, Visual', 'Space Perception', 'Zebrafish'] | 22,610,461 | [['B01.050'], ['B01.050.150.900.493.850.280'], ['G16.500.275', 'N06.230'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.778'], ['B01.050.150.900.493.200.244.828']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Operative treatment for intussusception: Should an incidental appendectomy be performed? | BACKGROUND/OBJECTIVES: An incidental appendectomy is performed by some surgeons during operative treatment for intussusception to eliminate future appendicitis as a diagnostic consideration. However, an appendectomy can increase the risk of infection and other noninfectious complications making an incidental appendecto... | ['Appendix', 'Child, Preschool', 'Databases, Factual', 'Digestive System Surgical Procedures', 'Enema', 'Female', 'Humans', 'Infant', 'Intussusception', 'Length of Stay', 'Male', 'Postoperative Complications', 'Retrospective Studies', 'Treatment Outcome'] | 30,583,859 | [['A03.556.124.526.209.290', 'A03.556.249.249.209.290'], ['M01.060.406.448'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.210'], ['E02.319.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C06.405.469.531.577'], ['E02.760.400.480', 'N02.421.585.400.480'], ['C23.550.767'], ['E05.31... | ['Anatomy [A]', 'Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Paroxysmal positional vertigo--a study of 255 cases. | The clinical and electronystagmographic findings of 255 patients with paroxysmal positional vertigo are presented. We believe the disorder should be diagnosed on the basis of the history and clinical findings since we did not find any characteristic electronystagmographic findings other than the recording of an actual ... | ['Adult', 'Aged', 'Electronystagmography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nystagmus, Pathologic', 'Posture', 'Vertigo'] | 691,098 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.380.230.280', 'E01.370.382.900.280', 'E01.370.405.245.787.280', 'E01.370.405.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.292.562.675', 'C11.590.400'], ['G11.427.695'], ['C09.218.568.900.883', 'C10.597.951', 'C23.888.592.958']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical usefulness of oral combination chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and cyclophosphamide for metastatic breast cancer. | BACKGROUND: It has been reported that 5'-deoxy-5-fluorouridine (5'-DFUR), the pro-drug of 5-FU, is effective treatment for breast cancer that express thymidine phosphorylase (dThdPase). Since oral cyclophosphamide (CPA) induces dThdPase, a synergistic effect can be expected by combining CPA with 5'-DFUR. We evaluated t... | ['Administration, Oral', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Cyclophosphamide', 'Female', 'Floxuridine', 'Humans', 'Middle Aged', 'Prospective Studies', 'Treatment Outcome'] | 17,146,158 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D03.383.742.680.852.300.350', 'D13.570.230.430.432', 'D13.570.685.852.300.350'], ['B01.050.150.900.649.313.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cinnamic aldehyde in toothpaste. 1. Clinical aspects and patch tests. | Although cinnamon is known to cause dermatitis in bakers and confectioners, it has only rarely been reported as causing trouble in food or cosmetics. A newly-formulated 'spicy' toothpaste containing cinnamon as a flavouring agent was the cause of oral symptoms in eight patients referred to clinics in Buckinghamshire an... | ['Acrolein', 'Adolescent', 'Adult', 'Cinnamomum zeylanicum', 'Female', 'Humans', 'Hypersensitivity', 'Male', 'Middle Aged', 'Patch Tests', 'Stomatitis', 'Toothpastes'] | 233,890 | [['D02.047.122'], ['M01.060.057'], ['M01.060.116'], ['B01.650.940.800.575.912.250.595.400.149.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['M01.060.116.630'], ['E01.370.225.812.871.610', 'E05.200.812.871.610', 'E05.478.594.890.610'], ['C07.465.864'], ['D25.376.711', 'J01.637.051.376.711']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
A giant cavernous hemangioma of the heart. | Cardiac hemangiomas are exceptionally rare, vascular neoplasms of the heart, with an incidence of 1% to 2% among all detected benign heart tumors. With the availability of the advanced imaging modalities of the heart, asymptomatic cardiac tumors are detected more frequently. These tumors are composed either of capillar... | ['Aged', 'Female', 'Heart Neoplasms', 'Hemangioma, Cavernous', 'Humans', 'Magnetic Resonance Imaging'] | 20,609,803 | [['M01.060.116.100'], ['C04.588.894.309', 'C14.280.459'], ['C04.557.645.375.385', 'C14.907.454.385', 'C15.378.463.515.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A questionnaire survey on attitude toward sperm cryopreservation among hematologists in Japan. | Advances in multimodal treatment have led to dramatic improvement in cancer treatment outcomes. It is now necessary to consider cancer patients' holistic quality of life. Fertility preservation is the top concern for cancer survivors of reproductive age. Sperm cryopreservation before treatment is recommended for postpu... | ['Adolescent', 'Adult', 'Antineoplastic Agents', 'Cryopreservation', 'Fertility Preservation', 'Hematology', 'Humans', 'Japan', 'Male', 'Quality of Life', 'Spermatozoa', 'Surveys and Questionnaires', 'Workforce', 'Young Adult'] | 27,844,197 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.248'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['E02.875.800.625', 'E04.936.537.562', 'E05.820.800.625'], ['H02.403.429.445'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The management of an early-missed abortion after radical trachelectomy--a case report and a review of the literature. | UNLABELLED: Radical trachelectomy (RT) has been reported for almost 20 years. This case report describes and addresses the issue of the clinical management of early-missed abortion in a patient after RT with a cerclage.CASE: A 35-year-old woman who had a RT 2 years ago due to cervical carcinoma stage IB1 presented with... | ['Abortion, Missed', 'Adult', 'Cerclage, Cervical', 'Female', 'Gynecologic Surgical Procedures', 'Humans', 'Postoperative Complications', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Pregnancy Outcome', 'Uterine Cervical Neoplasms'] | 16,884,386 | [['C13.703.039.173'], ['M01.060.116'], ['E04.520.100'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['G08.686.784.769'], ['C04.850', 'C13.703.720'], ['E01.789.700', 'G08.686.784.769.496'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.852.762.850', 'C13.351.9... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Idiopatic pulmonary fibrosis: A new paradigm]. | Idiopathic pulmonary fibrosis ((IPF) is the most common disease from a group of interstitial lung diseases, which occurs mainly in middle-aged and elderly people. Over the past decade, there have been considerable changes in approaches to diagnosing and treating IPF. The paper presents an update on the epidemiology of ... | ['Aged', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Lung Diseases, Interstitial', 'Middle Aged', 'Pulmonary Fibrosis'] | 28,635,908 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.765.500'], ['C08.381.483'], ['M01.060.116.630'], ['C08.381.765']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment adherence and illness insight in veterans with bipolar disorder. | Insight into the perceived value of psychotherapy and pharmacological treatment may improve adherence to medication regimens among patients with bipolar disorder, because patients are more likely to take medication they believe will make them better. We conducted a cross-sectional survey of patients recruited into the ... | ['Adult', 'African Continental Ancestry Group', 'Aged', 'Alcohol Drinking', 'Anticonvulsants', 'Antimanic Agents', 'Awareness', 'Bipolar Disorder', 'Combined Modality Therapy', 'Comorbidity', 'Cyclothymic Disorder', 'European Continental Ancestry Group', 'Female', 'Humans', 'Male', 'Middle Aged', 'Outcome Assessment, H... | 18,195,637 | [['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['F01.145.317.269'], ['D27.505.954.427.080'], ['D27.505.696.277.950.025', 'D27.505.954.427.210.950.025', 'D27.505.954.427.700.872.025'], ['F02.463.188.150'], ['F03.084.500'], ['E02.186'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.600.500'], ['M01.686.508.4... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Adiponectin and metabolic syndrome in middle-aged and elderly Chinese. | OBJECTIVE: Hypoadiponectinemia is an important risk factor for metabolic syndrome (MetS). However, little is known about its role in the Chinese population. The aim of this study was to investigate the association between plasma adiponectin levels and MetS in middle-aged and elderly Chinese from both urban and rural ar... | ['Adiponectin', 'Age Factors', 'Aged', 'China', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Odds Ratio', 'Prevalence', 'Risk Factors', 'Rural Population', 'Sex Characteristics', 'Urban Population'] | 18,223,631 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Differences in twenty-four-hour profiles of blue-light exposure between day and night shifts in female medical staff. | Light is the strongest zeitgeber currently known for the synchronization of the human circadian timing system. Especially shift workers are exposed to altered daily light profiles. Our objective is the characterization of differences in blue-light exposures between day and night shift taking into consideration modifyin... | ['Adult', 'Circadian Rhythm', 'Female', 'Germany', 'Humans', 'Linear Models', 'Middle Aged', 'Personnel, Hospital', 'Radiation Exposure', 'Shift Work Schedule'] | 30,759,543 | [['M01.060.116'], ['G07.180.562.190'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['M01.060.116.630'], ['M01.526.485.740',... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Late symptoms in infantile cystinosis. | Late symptoms of infantile cystinosis were evaluated in 19 patients aged 15-26 years who had a high graft survival following kidney transplantation. The end-stage cystinotic kidney was responsible for renal hypertension in 5 patients following grafts. Photophobia did not increase in relation to age, but 3 patients beca... | ['Adolescent', 'Adult', 'Child', 'Cystinosis', 'Humans', 'Hypertension, Renal', 'Kidney Transplantation', 'Time Factors'] | 3,153,326 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C16.320.565.595.377', 'C18.452.648.595.377'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.331', 'C13.351.968.419.331', 'C14.907.489.631'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of experimental corneal neovascularisation by bevacizumab (Avastin). | AIM: To evaluate the effect of topically administered bevacizumab (Avastin) on experimental corneal neovascularisation in rats.METHODS: Silver nitrate sticks (75% silver nitrate, 25% potassium nitrate) were used to perform chemical cauterisation on the corneas of 16 eyes from 16 male Long Evans rats. For the following ... | ['Angiogenesis Inhibitors', 'Animals', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Bevacizumab', 'Corneal Neovascularization', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Male', 'Photography', 'Rats', 'Rats, Long-Evans', 'Silver Nitrate', 'Vascular Endothelial Growth Factor A'] | 17,179,168 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D12.776.124.486.485.114... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ratio of nose blow results to intakes during the decommissioning of a facility at Dounreay. | During the decommissioning of a large glove box facility at Dounreay, in addition to engineering and administration controls, workers wore pressurised suits to minimise their intake of radionuclides. The workers provided nose blows after each suited operation to provide an indication of the effectiveness of protective ... | ['Biological Assay', 'Body Burden', 'Breath Tests', 'Computer Simulation', 'Decontamination', 'Exhalation', 'Humans', 'Inhalation', 'Models, Biological', 'Nasal Mucosa', 'Power Plants', 'Radiation Dosage', 'Radioisotopes', 'Radiometry', 'Relative Biological Effectiveness', 'Reproducibility of Results', 'Sensitivity and... | 18,223,182 | [['E05.091'], ['E05.799.638.231', 'N06.850.460.200'], ['E01.370.100'], ['L01.224.160'], ['N06.850.780.325'], ['G09.772.705.700.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.772.705.700.390'], ['E05.599.395'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['J01.780', 'J03.540.680'], ['E05.799.51... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Molecular properties from conformational ensembles. 1. Dipole moments of molecules with multiple internal rotations. | We present a novel method for constructing the stable conformational space of small molecules with many rotatable bonds that uses our iterative stochastic elimination (ISE) algorithm, a robust stochastic search method capable of finding ensembles of best solutions for large combinatorial problems. To validate the metho... | ['Algorithms', 'Models, Molecular', 'Molecular Conformation', 'Molecular Dynamics Simulation', 'Rotation'] | 21,210,653 | [['G17.035', 'L01.224.050'], ['E05.599.595'], ['G02.111.570.820'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G01.482.703']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acquired von Willebrand's syndrome resulting from untreated hypothyroidism in two prepubertal girls. | Acquired von Willebrand syndrome (AvWS) is a rare bleeding disorder associated with a number of different diseases, including hypothyroidism. We describe two prepubertal girls with AvWS and undiagnosed hypothyroidism due to thyroiditis Hashimoto. The patients had neither family history nor symptoms of bleeding disorder... | ['Child', 'Female', 'Hashimoto Disease', 'Humans', 'Hypothyroidism', 'von Willebrand Diseases'] | 17,083,524 | [['M01.060.406'], ['C19.874.871.102.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['C15.378.100.100.900', 'C15.378.100.141.900', 'C15.378.140.900', 'C15.378.463.920', 'C16.320.099.920']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A proteomic approach to analyze salt-responsive proteins in rice leaf sheath. | To examine the response of rice to salt stress, changes in protein expression were analyzed using a proteomic approach. To investigate dose- and time-dependent responses, rice seedlings were exposed to 50, 100 and 150 mM NaCl for 6 to 48 h. Proteins were extracted from leaf sheath and separated by two-dimensional polya... | ['Dose-Response Relationship, Drug', 'Electrophoresis, Gel, Two-Dimensional', 'Oryza', 'Peptides', 'Plant Leaves', 'Plant Proteins', 'Protein Structure, Tertiary', 'Proteomics', 'Salts', 'Sodium Chloride', 'Superoxide Dismutase', 'Time Factors'] | 15,221,768 | [['G07.690.773.875', 'G07.690.936.500'], ['E05.196.401.250', 'E05.301.300.230'], ['B01.650.940.800.575.912.250.822.616'], ['D12.644'], ['A18.024.812'], ['D12.776.765'], ['G02.111.570.820.709.610'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['D01.786'], ['D01.210.450.1... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
NO donors stimulate noradrenaline release from rat hippocampus in a calmodulin-dependent manner in the presence of L-cysteine. | Nitrogen oxides (NO) such as nitric oxide have been suggested to potentiate neurotransmitter release in a variety of neuronal cells. In this study, we showed that NO donors stimulate the release of noradrenaline (NA) from rat hippocampus both in vivo and in vitro. Co-addition of NO donors (sodium nitroprusside [SNP] or... | ['Animals', 'Calmodulin', 'Cyclic GMP', 'Cysteine', 'Enzyme Inhibitors', 'Glutathione', 'Hippocampus', 'In Vitro Techniques', 'Male', 'Nitric Oxide', 'Norepinephrine', 'Penicillamine', 'Rats', 'Rats, Wistar', 'S-Nitroso-N-Acetylpenicillamine', 'Stereoisomerism', 'Sulfhydryl Compounds'] | 8,841,425 | [['B01.050'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D27.505.519.389'], ['D12.644.456.448'], ['A08.186.211... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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