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[Interrupted alcohol treatment and liver: free radical homeostasis, nitric oxide, adaptive mechanisms]. | Alcohol administration can result in liver damage. Reactive oxygen species (ROS), nitric oxide (NO) and their interaction are crucial factors in this process. The aim of work was to investigate, free radical state and mechanisms of adaptation of the antioxidant system (AOS) to stress, caused by interrupted alcohol inta... | ['Adaptation, Physiological', 'Animals', 'Catalase', 'Ethanol', 'Homeostasis', 'Liver', 'Male', 'Nitric Oxide', 'Rats', 'Rats, Wistar', 'Reactive Oxygen Species', 'Superoxide Dismutase'] | 17,180,923 | [['G07.025', 'G16.012.500'], ['B01.050'], ['D08.811.682.732.332'], ['D02.033.375'], ['G07.410'], ['A03.620'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D01.339.431', 'D01.650.775'], ['D08.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Apparent normobasemia as a negative prognostic sign immediately after hepatectomy. | The acid-base balance from the postoperative day (POD) 1 to POD 3 after cirrhotic liver resection was investigated in relation to operative outcome by conducting a retrospective study on the changes in arterial ketone body ratio (AKBR), which reflects the hepatic mitochondrial redox state, and arterial blood gas analys... | ['Acid-Base Equilibrium', 'Aged', 'Aged, 80 and over', 'Alkalosis', 'Carcinoma, Hepatocellular', 'Female', 'Hepatectomy', 'Humans', 'Liver Cirrhosis', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prognosis'] | 8,383,380 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C18.452.076.354'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.55... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modelling evolutionary processes in small populations: not as ideal as you think. | Evolutionary processes are routinely modelled using 'ideal' Wright-Fisher populations of constant size N in which each individual has an equal expectation of reproductive success. In a hypothetical ideal population, variance in reproductive success (V(k)) is binomial and effective population size (N(e)) = N. However, i... | ['Algorithms', 'Alleles', 'Biological Evolution', 'Computer Simulation', 'Gene Frequency', 'Genetics, Population', 'Linkage Disequilibrium', 'Models, Genetic'] | 19,344,355 | [['G17.035', 'L01.224.050'], ['G05.360.340.024.340.030'], ['G05.045', 'G16.075'], ['L01.224.160'], ['G05.330'], ['H01.158.273.343.335'], ['G05.348.500'], ['E05.599.395.397']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Dialectical behavior therapy for adolescent binge eating, purging, suicidal behavior, and non-suicidal self-injury: a pilot study. | There are few published randomized controlled trials examining treatment for symptoms of bulimia nervosa (BN) in adolescents. Additionally, many adolescents presenting for treatment for BN symptoms endorse co-occurring mood disturbances, suicidality, and nonsuicidal self-injury (NSSI), and may not meet full Diagnostic ... | ['Adolescent', 'Adolescent Behavior', 'Behavior Therapy', 'Binge-Eating Disorder', 'Bulimia Nervosa', 'Feasibility Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Pilot Projects', 'Self-Injurious Behavior', 'Suicide, Attempted', 'Treatment Outcome'] | 24,773,094 | [['M01.060.057'], ['F01.145.022'], ['F04.754.137'], ['F03.400.188'], ['F03.400.250'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.37... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Primary carcinoma of the fallopian tube. | The present report of 16 new cases of fallopian tube carcinoma also includes 2 new cases of adenoacanthoma, an exceedingly rare tumor. The histologic evaluation of tubal carcinoma is discussed. A meticulous search at surgery for occult disease is urged, because penetration of the tubal serosa seems to be the most impor... | ['Adenocarcinoma', 'Adult', 'Aged', 'Fallopian Tube Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Prognosis'] | 7,465,152 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.945.418.365', 'C13.351.500.056.390.390', 'C13.351.937.418.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Modified Iliac Screw: An Anatomic Comparison and Technical Guide. | BACKGROUND: Iliac screws are a widely used sacropelvic fixation technique, which is often criticized for its impaired wound healing owing to hardware prominence. The aim of this study was to present a modified iliac screw (MIS) fixation technique that uses a different entry point more medially and caudally to the poste... | ['Aged', 'Bone Screws', 'Cadaver', 'Female', 'Humans', 'Ilium', 'Lumbar Vertebrae', 'Male', 'Prosthesis Design'] | 31,981,785 | [['M01.060.116.100'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825.434'], ['A02.835.232.834.519'], ['E05.320.550', 'E07.695.680']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preparation and characterization of echogenic liposome as an ultrasound contrast agent: size-dependency and stabilizing effect of cholesterol on the echogenicity of gas-entrapping liposome. | The liposome entrapping CO2 gas inside the vesicle, which is called the echogenic liposome, has been made and characterized in vitro as an ultrasound contrast agent. The small unilamellar vesicle (SUV), large unilamellar vesicle (LUV) and multilamellar vesicle (MLV) as echogenic liposomes were compared in their echogen... | ['Chemical Phenomena', 'Chemistry, Physical', 'Cholesterol', 'Contrast Media', 'Densitometry', 'Drug Carriers', 'Liposomes', 'Membranes, Artificial', 'Particle Size', 'Ultrasonography'] | 9,810,688 | [['G02'], ['H01.181.529'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D27.505.259.500', 'D27.720.259'], ['E05.196.712.224'], ['D26.255.260', 'E02.319.300.380'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D25.479', 'J01.637.051.479', 'J01.637.087... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
The effect of oxygen and carbon dioxide on the development of the free-living stages of Strongyloides ratti in axenic culture. | The effect of oxygen and carbon dioxide concentration on the development of the free-living stages of Strongyloides ratti in axenic culture was examined. Hatching of S. ratti eggs was inhibited at very low oxygen levels. Development of all organisms was inhibited in medium gassed with less than 4% O2 in 0.03% CO2 with ... | ['Animals', 'Carbon Dioxide', 'Female', 'Male', 'Oxygen', 'Strongyloides'] | 2,116,514 | [['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.268.185.550', 'D01.362.670'], ['B01.050.500.500.294.400.875.640.680']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quality of websites of obstetrics and gynecology departments: a cross-sectional study. | BACKGROUND: The internet has become an easily accessible and widely used source of healthcare information. There are, however, no standardized or commonly accepted criteria for the quality of Obstetrics and Gynecology websites. In this study, we aimed to evaluate the quality of websites of Obstetrics and Gynecology dep... | ['Austria', 'Cross-Sectional Studies', 'Female', 'Germany', 'Gynecology', 'Humans', 'Information Dissemination', 'Internet', 'Linear Models', 'Medical Informatics', 'Multivariate Analysis', 'Obstetrics', 'Quality Control', 'Switzerland'] | 25,928,159 | [['Z01.542.088'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.315'], ['H02.403.763.750', 'H02.403.810.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['L01.224.230.110.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Decreased expression of heparanase in glioblastoma multiforme. | OBJECT: The authors investigated the presence of endoglycosidase heparanase in human glioblastoma multiforme (GBM) and metastatic brain tumors as well as in healthy brain tissue to explore the relationship between the biological characteristics of GBM and the role of heparanase.METHODS: Heparanase messenger (m)RNA was ... | ['Animals', 'Brain Neoplasms', 'Down-Regulation', 'Female', 'Glioblastoma', 'Glucuronidase', 'Humans', 'Immunohistochemistry', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction'] | 15,796,387 | [['B01.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['D08.811.277.450.426'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.5... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Direct-Ink-Write 3D Printing of Hydrogels into Biomimetic Soft Robots. | Hydrogels are promising starting materials for biomimetic soft robots as they are intrinsically soft and hold properties analogous to nature's organic parts. However, the restrictive mold-casting and post-assembly fabrication alongside mechanical fragility impedes the development of hydrogel-based soft robots. Herein, ... | ['Biocompatible Materials', 'Hydrogels', 'Printing, Three-Dimensional'] | 31,625,724 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D20.280.320.375', 'D26.255.165.320.375'], ['J01.897.564', 'L01.224.108.150.500', 'L01.296.110.150.500']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Fibroblastic osteosarcoma with epithelioid and squamous differentiation in a dog. | A fibroblastic osteosarcoma with epithelioid and squamous differentiation in the distal femur of a 9-y-old spayed female Greyhound dog is described. Grossly, the tumor consisted of a pale-white, firm-to-hard mass that replaced the medullary and cortical areas of the distal end of the right femur. Histologically, the ma... | ['Animals', 'Bone Neoplasms', 'Cell Differentiation', 'Dog Diseases', 'Dogs', 'Female', 'Immunohistochemistry', 'Male', 'Osteocalcin', 'Osteosarcoma', 'Vimentin'] | 29,629,646 | [['B01.050'], ['C04.588.149', 'C05.116.231'], ['G04.152'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.5... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Transgenic mouse model of intestine-specific mucosal injury and repair. | Most studies of injury and repair to mucosal tissue have used nonspecific mediators to induce injury. Damage to the mucosal epithelium resulting from chemical or radiation treatment associated with cancer therapy may fall into this category of injury. When such treatments are applied, it is generally not possible to pr... | ['Animals', 'Body Weight', 'CD8-Positive T-Lymphocytes', 'Cell Line', 'DNA, Complementary', 'Disease Models, Animal', 'Epithelial Cells', 'Flow Cytometry', 'Inflammatory Bowel Diseases', 'Intestinal Mucosa', 'Lymphocytes', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Mucous Membrane', 'RNA', 'Transgenes'] | 11,694,561 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['A11.251.210'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.2... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-density mapping and ablation of concealed low-voltage activity within pulmonary vein antra results in improved freedom from atrial fibrillation compared to pulmonary vein isolation alone. | BACKGROUND: Despite advancements, the goal of durable pulmonary vein isolation (PVI) in all patients undergoing ablation for atrial fibrillation (AF) remains elusive. New high-density mapping (HDM) allows detection of concealed low-voltage signals (CLVSs) that persist after PVI and may represent vulnerabilities in the ... | ['Aged', 'Atrial Fibrillation', 'Case-Control Studies', 'Catheter Ablation', 'Epicardial Mapping', 'Female', 'Follow-Up Studies', 'Heart Conduction System', 'Humans', 'Male', 'Pulmonary Veins', 'Recurrence', 'Time Factors', 'Treatment Outcome'] | 29,729,399 | [['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.808.750.500', 'E04.014.760.500'], ['E01.370.370.380.245.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A07.541.409'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mild Deficits of Cortical Bone in Young Adults With Klinefelter Syndrome or Anorchia Treated With Testosterone. | CONTEXT: There are currently no data evaluating volumetric bone mineral density (BMD), bone geometry, and body composition in adults with Klinefelter syndrome (KS) or anorchia who have been treated with T from adolescence.OBJECTIVE: To determine volumetric BMD, bone geometry using peripheral quantitative computed tomog... | ['Adult', 'Body Composition', 'Bone Density', 'Bone and Bones', 'Gonadal Dysgenesis, 46,XY', 'Humans', 'Klinefelter Syndrome', 'Male', 'Middle Aged', 'Radiography', 'Testis', 'Testosterone', 'Young Adult'] | 26,186,297 | [['M01.060.116'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['C12.706.316.096.687', 'C12.706.316.309.388', 'C13.351.875.253.096.687', 'C13.351.875.253.309.388', 'C16.131.939.316.096.687', 'C16.131.939.316.309.388', 'C19.391.119.096.687', 'C19.391.119.309.388'], ['B01.05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A survey of dioxins (PCDDs and PCDFs) and dioxin-like PCBs in sheep and goat milk from Campania, Italy. | In 2008, after the crisis of buffalo dairy fields in Campania, Italy, an assessment of the contamination of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) was also necessary for other animal species bred in the region. The contents of PC... | ['Animals', 'Benzofurans', 'Buffaloes', 'Dibenzofurans, Polychlorinated', 'Dioxins', 'Food Contamination', 'Gas Chromatography-Mass Spectrometry', 'Goats', 'Italy', 'Maximum Allowable Concentration', 'Milk', 'Polychlorinated Biphenyls', 'Polychlorinated Dibenzodioxins', 'Sheep'] | 24,785,317 | [['B01.050'], ['D03.633.100.127'], ['B01.050.150.900.649.313.500.380.135'], ['D02.309.250', 'D03.633.300.258.500'], ['D02.309.500', 'D03.383.231'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.500.380.513'], ['Z01.542.48... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Effect of diclofenac and antidepressants on the inflammatory response in astrocyte cell culture. | Central nervous system (CNS) has a completely separate immune system that communicates with the neurons by small molecules called cytokines. Cytokines are involved in many crucial processes in neuron including cell metabolism and neurotransmitter synthesis. It has been reported that cytokine imbalance is involved in th... | ['Animals', 'Animals, Newborn', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antidepressive Agents', 'Astrocytes', 'Cells, Cultured', 'Cyclohexanols', 'Diclofenac', 'Enzyme-Linked Immunosorbent Assay', 'Fluvoxamine', 'Interleukin-10', 'Lipopolysaccharides', 'Mice', 'Pyridoxine', 'Serotonin Uptake Inhibitors', 'Sertralin... | 23,896,940 | [['B01.050'], ['B01.050.050.282'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.954.427.700.122'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['D02.241.223.601.210'], ['E05.478.566.350.170', 'E05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Skull metastasis of thyroid papillary carcinoma. | Skull metastasis of thyroid carcinoma is rare. The majority of skull metastases of thyroid carcinoma are of the follicular subtype, rather than thyroid papillary carcinoma. In this report, a 55-year-old woman with skull metastasis from thyroid papillary carcinoma is presented. The metastatic lesion of the skull was hyp... | ['Aged', 'Carcinoma, Papillary', 'Female', 'Humans', 'Male', 'Middle Aged', 'Review Literature as Topic', 'Skull Neoplasms', 'Thyroid Neoplasms'] | 17,386,370 | [['M01.060.116.100'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['L01.178.682.759'], ['C04.588.149.721', 'C05.116.231.754'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Why Chlamydia pneumoniae is associated with asthma and other chronic conditions? Suggestions from a survey in unselected 9 yr old schoolchildren. | Despite numerous studies demonstrating an association between asthma and many other chronic conditions and signs of Chlamydia pneumoniae (Cp) infection, the role of Cp in the pathogenesis of these illness remain still unclear. We investigated the prevalence of Cp antigen in the upper airways and the prevalence of detec... | ['Animals', 'Antibodies, Bacterial', 'Antigens, Bacterial', 'Asthma', 'Child', 'Chlamydia Infections', 'Chlamydophila pneumoniae', 'Chronic Disease', 'DNA', 'Female', 'Humans', 'Hypersensitivity, Immediate', 'Immunoglobulin G', 'Male', 'Nasal Mucosa', 'Polymerase Chain Reaction'] | 15,787,872 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The role of GlcNAc-PI-de-N-acetylase gene by gene knockout through homologous recombination and its consequences on survival, growth and infectivity of Leishmania major in in vitro and in vivo conditions. | At present, there are no efficacious vaccines or effective drugs against leishmaniasis; therefore new and innovative control methods are urgently required. One way to achieve this important goal is through using reverse genetic engineering to evaluate important enzymes, proteins and macromolecules. One of the most impo... | ['Amidohydrolases', 'Animals', 'Cell Line', 'Female', 'Gene Knockout Techniques', 'Genotype', 'Homologous Recombination', 'Leishmania major', 'Mice', 'Mice, Inbred BALB C'] | 26,571,069 | [['D08.811.277.087'], ['B01.050'], ['A11.251.210'], ['E05.393.335.750'], ['G05.380'], ['G05.728.615'], ['B01.268.475.868.488.405'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
VFMSS findings in elderly dysphagic patients: our experience. | BACKGROUND: Dysphagia consists in alteration of the swallowing mechanism, due to different pathological conditions, which can occur at different levels. The exact prevalence of dysphagia is unclear, even if some AA suggest that 15% of the elderly population is affected. Aim of this study is to analyze the main VFMSS fi... | ['Aged', 'Aged, 80 and over', 'Deglutition Disorders', 'Diagnostic Techniques, Digestive System', 'Female', 'Fluoroscopy', 'Humans', 'Male', 'Manometry', 'Retrospective Studies', 'Video Recording'] | 24,267,870 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C06.405.117.119', 'C09.775.174'], ['E01.370.372'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Activation of mast cells is essential for development of house dust mite Dermatophagoides farinae-induced allergic airway inflammation in mice. | In this study, we demonstrate that Dermatophagoides farinae (Der f), a major source of airborne allergens, but not OVA, could rapidly activate mast cells in mice. This was indicated by an elevation of serum mouse mast cell protease 1, a mast cell-specific proteinase, as early as 30 min after intratracheal challenge. Ad... | ['Allergens', 'Animals', 'Antigens, CD', 'B7-1 Antigen', 'B7-2 Antigen', 'Cell Division', 'Cell Line, Tumor', 'Cell-Free System', 'Cells, Cultured', 'Chemokines', 'Cytokines', 'Dermatophagoides farinae', 'Dust', 'Inflammation', 'Inflammation Mediators', 'Intubation, Intratracheal', 'Macrophages, Alveolar', 'Mast Cells'... | 14,500,682 | [['D23.050.063'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D12.776.467.150.100', 'D12.776.543.095.100', 'D23.050.301.285.100', 'D23.529.168.100'], ['D12.776.465.500', 'D12.776.467.150.200', 'D12.776.543.095.200', 'D23.050.301.285.200', 'D23.529.168.200'], ['G04.144.220', 'G04.161.750.500', 'G05.113', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The domain architecture of cytochrome P450BM-3. | Cytochromes P450 utilize redox partners to deliver electrons from NADPH/NADH to the P450 heme center. Microsomal P450s utilize an FAD/FMN reductase. The bacterial fatty acid hydroxylase, P450BM-3, is similar except the P450 heme and FAD/FMN proteins are linked together in a single polypeptide chain arranged as heme-FMN... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Cytochrome P-450 Enzyme System', 'FMN Reductase', 'Flavin-Adenine Dinucleotide', 'Heme', 'Mixed Function Oxygenases', 'Molecular Sequence Data', 'Mutagenesis', 'NADH, NADPH Oxidoreductases', 'NADPH-Ferrihemoprotein Reductase', 'Protein Folding', 'Sequence Deletion', 'Seque... | 9,065,459 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D08.811.682.662.171'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', 'D08.211.474.650.249', 'D13.695.667.138.506', 'D13.695.827.068.506', 'D23.76... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP) sites in A172 cells. | PURPOSE: To detect the effects of extremely low frequency (ELF) magnetic fields, the number of apurinic/apyrimidinic (AP) sites in human glioma A172 cells was measured following exposure to ELF magnetic fields.MATERIALS AND METHODS: The cells were exposed to an ELF magnetic field alone, to genotoxic agents (methyl meth... | ['Cell Line, Tumor', 'Cell Survival', 'DNA', 'DNA Damage', 'Electromagnetic Fields', 'Humans', 'Hydrogen Peroxide', 'Methyl Methanesulfonate', 'Mutagens', 'Purines', 'Pyrimidines', 'Radiation Tolerance'] | 17,852,556 | [['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D13.444.308'], ['G05.200'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D02.455.326.146.100.050.500.500', 'D02.886.645.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation for bleeding disorders in suspected child abuse. | Bruising or bleeding in a child can raise the concern for child abuse. Assessing whether the findings are the result of trauma and/or whether the child has a bleeding disorder is critical. Many bleeding disorders are rare, and not every child with bruising/bleeding concerning for abuse requires an evaluation for bleedi... | ['Blood Coagulation Disorders', 'Blood Coagulation Tests', 'Child', 'Child Abuse', 'Child, Preschool', 'Contusions', 'Decision Support Techniques', 'Diagnosis, Differential', 'Hemorrhage', 'Hemorrhagic Disorders', 'Humans', 'Infant', 'Infant, Newborn', 'Intracranial Hemorrhages', 'Vitamin K Deficiency Bleeding'] | 23,530,182 | [['C15.378.100'], ['E01.370.225.625.115', 'E05.200.625.115'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.060.406.448'], ['C26.974.250'], ['E05.245', 'L01.313.500.750.190'], ['E01.171'], ['C23.550.414'], ['C15.378.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703']... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Early short photoperiod effects in female LSH/SsLak Syrian hamsters. | Previous experiments showed that LSH/SsLak female hamsters cease ovarian cyclicity after 2-4 weeks of short photoperiod (SP) treatment. This study was designed to reveal early hormonal and histological changes on day 1 of the estrous cycle (estrus) in SP-treated animals and changes brought about by the SP-induced acycl... | ['Anestrus', 'Animals', 'Cricetinae', 'Estrus', 'Female', 'Follicle Stimulating Hormone', 'Light', 'Mesocricetus', 'Organ Size', 'Ovary', 'Pituitary Gland, Anterior', 'Prolactin', 'Uterus'] | 3,096,700 | [['G08.686.195.249'], ['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['G08.686.195.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.992.635.075.250.500'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prevention and treatment of pneumonia in infectious complications of trauma]. | Based on the examination and treatment of 79 patients with traumas the authors consider ventilation exercises to be necessary for prevention of pneumonia. | ['Adult', 'Combined Modality Therapy', 'Exercise Therapy', 'Female', 'Humans', 'Male', 'Pneumonia', 'Respiratory Therapy', 'Wound Infection'] | 3,388,717 | [['M01.060.116'], ['E02.186'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['E02.880'], ['C01.947']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reactive oxygen species-scavenging nanomedicines for the treatment of oxidative stress injuries. | This Progress Report describes a development of two types of reactive oxygen species (ROS)-scavenging nanomedicines for the treatment of oxidative stress injuries, referred to as pH-sensitive redox nanoparticle (RNP(N) ) and pH-insensitive redox nanoparticle (RNP(O) ), which are prepared by self-assembling amphiphilic ... | ['Animals', 'Antineoplastic Agents', 'Cyclic N-Oxides', 'Drug Carriers', 'Free Radical Scavengers', 'Humans', 'Hydrogen-Ion Concentration', 'Inflammation', 'Mice', 'Nanomedicine', 'Nanoparticles', 'Neoplasms', 'Nitrogen Oxides', 'Oxidation-Reduction', 'Polymers', 'Reactive Oxygen Species', 'Reperfusion Injury', 'Spin L... | 24,482,427 | [['B01.050'], ['D27.505.954.248'], ['D03.661.243'], ['D26.255.260', 'E02.319.300.380'], ['D27.505.519.217.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.500'], ['H01.603.600', 'J01.897.120.050.625', 'J01.897.520.600.600'], ['J01.637.512.600'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Functional Identification of Target by Expression Proteomics (FITExP) reveals protein targets and highlights mechanisms of action of small molecule drugs. | Phenomenological screening of small molecule libraries for anticancer activity yields potentially interesting candidate molecules, with a bottleneck in the determination of drug targets and the mechanism of anticancer action. We have found that, for the protein target of a small-molecule drug, the abundance change in l... | ['Antineoplastic Agents', 'Apoptosis', 'Camptothecin', 'Cell Line, Tumor', 'Computational Biology', 'Doxorubicin', 'Drug Discovery', 'Fluorouracil', 'HCT116 Cells', 'Humans', 'Methotrexate', 'Paclitaxel', 'Proteome', 'Proteomics', 'Quinazolines', 'Small Molecule Libraries', 'Thiophenes'] | 26,052,917 | [['D27.505.954.248'], ['G04.146.954.035'], ['D03.132.151'], ['A11.251.210.190', 'A11.251.860.180'], ['H01.158.273.180', 'L01.313.124'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['D03.383.742.698.875.404'], ['A11... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Diabetic control with gliquidone--a short acting sulphonylurea. | Gliquidone (Glurenorm) and glibenclamide were compared in a cross-over study of 20 non insulin dependent diabetics. Both drugs achieved similar levels of control, as measured by self home monitoring, glycosylated haemoglobin and N-acetyl-beta-D-glucosamidase levels. However, with glibenclamide hyperglycaemic control wa... | ['Adolescent', 'Adult', 'Aged', 'Blood Glucose', 'Clinical Trials as Topic', 'Diabetes Mellitus, Type 2', 'Dietary Carbohydrates', 'Female', 'Glyburide', 'Glycated Hemoglobin A', 'Hexosaminidases', 'Humans', 'Hypoglycemic Agents', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Random Allocation', 'Sulfonylurea Comp... | 6,428,917 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D02.065.950.828.575', 'D02.886.590.795.575'], ['D09.400.430.937', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Sub-lethal concentrations of antibiotics increase mutation frequency in the cystic fibrosis pathogen Pseudomonas aeruginosa. | Approximately 80% of adult patients with cystic fibrosis (CF) become chronically infected with Pseudomonas aeruginosa and consequently require antibiotic therapy at intervals throughout their lives. Achieving lethal concentrations of antibiotics in the lung remains a challenge. Recent evidence from Escherichia coli and... | ['Aminoglycosides', 'Anti-Bacterial Agents', 'Cystic Fibrosis', 'Drug Resistance, Bacterial', 'Humans', 'Microbial Sensitivity Tests', 'Mutation Rate', 'Pseudomonas aeruginosa', 'beta-Lactams'] | 23,206,221 | [['D09.408.051'], ['D27.505.954.122.085'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G05.045.250.750', 'G05.365.590.612', 'G16.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of acculturation on frailty among older Mexican Americans. | OBJECTIVE: To determine the effect of acculturation on becoming frail and prefrail over a 10-year period among older Mexican Americans.METHOD: A nationally representative sample of 2,049 Mexican Americans aged 67 to 108 was analyzed. Adjusted for sociodemographics and health, longitudinal multinomial mixed models exami... | ['Acculturation', 'Activities of Daily Living', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Confidence Intervals', 'Female', 'Frail Elderly', 'Hispanic Americans', 'Humans', 'Language', 'Linear Models', 'Longitudinal Studies', 'Male', 'Odds Ratio', 'Time Factors', 'United States'] | 21,189,315 | [['I01.076.201.450.050', 'I01.880.853.100.079'], ['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['M01.060.116.100.540'], ['M01.686.754.441']... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Trichinella spiralis: antifecundity and antinewborn larvae immunity in swine. | The development of antifecundity and antinewborn larvae immunity in swine infected with Trichinella spiralis was investigated. In primary infections, adult female worm fecundity dropped sharply after 3 weeks, although adults could be recovered from the small intestine for at least 7 weeks after infection. In challenge ... | ['Age Factors', 'Animals', 'Antibodies', 'Immunization, Passive', 'Larva', 'Muscles', 'Reproduction', 'Swine', 'Trichinella'] | 3,780,929 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A02.633', 'A10.690'], ['G08.686.784'], ['B01.050.150.900.649.313.500.880'], ['B01.050.500... | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The microvasculature of the 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary tumour. I. Vascular patterns as visualized by scanning electron microscopy of corrosion casts. | We examined the microvasculature of the 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary tumour by scanning electron microscopy of corrosion casts. An elaborate vascular envelope predominantly consisting of sinusoidal and venular vessels was formed around each tumour nodule. These vessels exhibited various abn... | ['9,10-Dimethyl-1,2-benzanthracene', 'Animals', 'Capillaries', 'Female', 'Mammary Glands, Animal', 'Mammary Neoplasms, Experimental', 'Microcirculation', 'Microscopy, Electron, Scanning', 'Rats', 'Rats, Inbred Strains'] | 1,899,955 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['B01.050'], ['A07.015.461.165'], ['A10.336.482', 'A13.589'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['G09.330.100.645'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metal accumulation from dietary exposure in the sea urchin, Strongylocentrotus droebachiensis. | Metal contamination is a common problem in aquatic environments and may result in metal bioaccumulation and toxicity in aquatic biota. Recent studies have reported the significance of dietary metal accumulation in aquatic food chains, particularly in species of lower trophic levels. This research investigated the accum... | ['Animals', 'Diet', 'Environmental Exposure', 'Food Chain', 'Herbivory', 'Metals, Heavy', 'Seaweed', 'Strongylocentrotus', 'Water Pollutants, Chemical'] | 22,402,781 | [['B01.050'], ['G07.203.650.240'], ['N06.850.460.350'], ['G16.500.275.157.250', 'N06.230.124.250'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07.203.650.353.758'], ['D01.268.556', 'D01.552.544'], ['B05.080.750'], ['B01.050.500.408.578.800'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ectopic testicular xenografts from newborn hamsters (Phodopus sungorus) show better spermatogenic activity in aged compared with young recipients. | The mechanisms behind testicular aging are poorly understood. Previous studies suggest that the testicular microenvironment is more affected by age than the male germ cell lineage. Here we analyze male reproductive aging using a unique xenografting approach. By exposing young and aged mice to newborn hamster testicular... | ['Aging', 'Animals', 'Animals, Newborn', 'Cricetinae', 'Male', 'Orchiectomy', 'Phodopus', 'Spermatogenesis', 'Testis', 'Transplantation, Heterologous'] | 18,412,097 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.992.635.075.250'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'], ['B01.050.150.900.649.313.992.635.075.250.630'], ['G04.152.650.624', 'G08.686.784.310.760'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.312.782'], ['E04.93... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The extent of nonmedical use of psychoactive substances among secondary school students in Greater Cairo. | The present paper reports on an epidemiological study of the nonmedical use of psychoactive substances among male secondary school students in Greater Cairo. A standardized questionnaire was administered to 5530 male pupils constituting a representative sample of all male students in Cairo secondary schools. The main a... | ['Adolescent', 'Adult', 'Art', 'Child', 'Egypt', 'Ethanol', 'Humans', 'Mass Media', 'Mathematics', 'Narcotics', 'Plants, Toxic', 'Psychotropic Drugs', 'Science', 'Social Facilitation', 'Students', 'Substance-Related Disorders', 'Tobacco'] | 7,084,022 | [['M01.060.057'], ['M01.060.116'], ['K01.093'], ['M01.060.406'], ['Z01.058.266.317'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.590'], ['H01.548'], ['D27.505.696.277.600', 'D27.505.696.663.850.014.760', 'D27.505.954.427.040.550', 'D27.505.954.427.210.600'], ['B01.650.660'], ['D27.505.9... | ['Named Groups [M]', 'Humanities [K]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 |
[Treatment and prevention of paroxysmal atrial fibrillation and flutter with quinidine retard]. | The ability of quinidine retard of restoring sinus rhythm and further maintenance after successful regulation were checked in 42 patients with flutter and fibrillation in an open clinical trial. Quinidine retard restores the sinus rhythm in less patients (60.0%) than quinidine sulphate (81,8%). At the same time, it mai... | ['Adult', 'Aged', 'Atrial Fibrillation', 'Atrial Flutter', 'Clinical Trials as Topic', 'Delayed-Action Preparations', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Quinidine'] | 3,895,746 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['C14.280.067.248', 'C23.550.073.248'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D26.255.210', 'E02.319.300.253'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acardia: predictive risk factors for the co-twin's survival. | This study aimed to find factors in acardiac pregnancies that could be used to predict survival rates of the pump fetus. Five cases of acardia at Monash Medical Centre were found, and all case reports available in the literature from 1960 to 1991 (184 cases) were collected and analyzed. Acardia is more common in nullip... | ['Diseases in Twins', 'Female', 'Heart Defects, Congenital', 'Humans', 'Male', 'Pregnancy', 'Prenatal Diagnosis', 'Risk Factors', 'Survival Analysis'] | 7,871,485 | [['C23.550.291.750'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E01.370.378.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['E05.318.740.998',... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[A primary undifferentiated pleomorph cardiac sarcoma. Case report]. | The aim of the study was to characterize the clinical and histological picture of a malignant cardiac tumor, to assess the prognosis and to develop a management strategy. We described a primary cardiac sarcoma, located in the right ventricle. Minimal invasive right thoracotomy was used and a partial surgical excision o... | ['Adult', 'Cardiac Surgical Procedures', 'Female', 'Heart Neoplasms', 'Heart Ventricles', 'Humans', 'Palliative Care', 'Prognosis', 'Sarcoma'] | 17,595,853 | [['M01.060.116'], ['E04.100.376', 'E04.928.220'], ['C04.588.894.309', 'C14.280.459'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.666', 'N02.421.585.666'], ['E01.789'], ['C04.557.450.795']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The accuracy of digital image-based finite element models. | Digital image-based finite element meshing is an alternative approach to time-consuming conventional meshing techniques for generating realistic three-dimensional (3D) models of complex structures. Although not limited to biological applications, digital image-based modeling has been used to generate structure-specific... | ['Bone and Bones', 'Computer Simulation', 'Elasticity', 'Finite Element Analysis', 'Forecasting', 'Humans', 'Models, Biological', 'Oscillometry', 'Reproducibility of Results', 'Stress, Mechanical'] | 10,412,392 | [['A02.835.232', 'A10.165.265'], ['L01.224.160'], ['G01.374.590'], ['E05.355'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.654'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G01.374.835']] | ['Anatomy [A]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
3D printing individualized heel cup for improving the self-reported pain of plantar fasciitis. | BACKGROUND: To explore the therapeutic effect and the biomechanical mechanism of 3D printing individualized heel cup in treating of plantar heel pain.METHODS: The clinical effect was evaluated by plantar pressure analysis and pain assessment in participants. Its biomechanical mechanism of protecting the plantar heel wa... | ['Computer Simulation', 'Fasciitis, Plantar', 'Finite Element Analysis', 'Heel', 'Humans', 'Pain', 'Pressure', 'Printing, Three-Dimensional', 'Reproducibility of Results', 'Self Report', 'Walking'] | 29,914,501 | [['L01.224.160'], ['C05.321.600', 'C05.360.350'], ['E05.355'], ['A01.378.610.250.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['G01.374.715'], ['J01.897.564', 'L01.224.108.150.500', 'L01.296.110.150.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.... | ['Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Soc... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Factors that affect the rate of retakes for endodontic treatment radiographs. | The purpose of this study was to determine the most accurate method of taking radiographs during endodontic treatment to minimize the number of retakes. To accomplish this, the rate of retakes in an endodontic clinic at a dental school was measured. Then the effect that two factors, anatomic location and type of film h... | ['Clinical Competence', 'Dental Pulp Cavity', 'Humans', 'Quality Assurance, Health Care', 'Radiography, Dental'] | 8,028,875 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['A14.549.167.900.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700', 'N05.700'], ['E01.370.350.700.720', 'E06.342.764']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Hematological and Running Performance Modification of Trained Athletes after Reverse vs. Block Training Periodization. | The aim of the present study was to analyze the effect of block (BP) and a reverse training periodization (RP) in the hematological and running performance of amateur trained athletes. Modifications in hematological, aerobic, and anaerobic running performance and countermovement jump before and after twelve weeks of BP... | ['Athletes', 'Athletic Performance', 'Female', 'Heart Rate', 'Humans', 'Male', 'Oxygen Consumption', 'Running', 'Triglycerides'] | 32,635,515 | [['M01.072'], ['I03.450.642.845.054'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.680'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['D10.351.801']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Predictive significance of the cut-off value of CD20 expression in patients with B-cell lymphoma. | The introduction of the anti-CD20 monoclonal antibody, rituximab, into the treatment of patients with B-cell lymphomas has improved the overall response rate, as well as the response duration and the overall survival of these patients. However, only a few studies have addressed the question of whether higher CD20 expre... | ['Antibodies, Monoclonal, Murine-Derived', 'Antigens, CD20', 'Antineoplastic Agents', 'Biomarkers, Tumor', 'Cell Separation', 'Disease-Free Survival', 'Drug Resistance, Neoplasm', 'Flow Cytometry', 'Humans', 'Kaplan-Meier Estimate', 'Lymphoma, B-Cell', 'Prognosis', 'Rituximab'] | 20,811,695 | [['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120', 'D23.101.100.150.120'], ['D27.505.954.248'], ['D23.101.140'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.789.800... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Redesigning the NEDD8 pathway with a bacterial genetic screen for ubiquitin-like molecule transfer. | Pathways of ubiquitin-like (UBL) molecule transfer regulate a myriad of cellular cascades. Here, we report a high-throughput assay that correlates catalytic human NEDD8 transfer to bacterial survival. The assay was utilized to screen mutant NEDD8 and NAE (NEDD8-activating enzyme) libraries to engineer a more stable NED... | ['Amino Acid Sequence', 'Binding Sites', 'Escherichia coli', 'High-Throughput Screening Assays', 'Humans', 'Microbial Viability', 'Models, Molecular', 'Mutation', 'NEDD8 Protein', 'Protein Engineering', 'Signal Transduction', 'Ubiquitin', 'Ubiquitin-Activating Enzymes', 'Ubiquitin-Conjugating Enzymes', 'Ubiquitins'] | 22,391,419 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.916.680'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.580'], ['E05.599.595'], ['G05.365.590'], ['D12.776.947.218'], ['E05.393.420.601'], ['G02.111.820', 'G04.835'], ['D12.776.947.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Offline pentafluorophenyl (PFP)-RP prefractionation as an alternative to high-pH RP for comprehensive LC-MS/MS proteomics and phosphoproteomics. | Technological advances in liquid chromatography and tandem mass spectrometry (LC-MS/MS) have enabled comprehensive analyses of proteins and their post-translational modifications from cell culture and tissue samples. However, sample complexity necessitates offline prefractionation via a chromatographic method that is o... | ['Chromatography, High Pressure Liquid', 'Chromatography, Reverse-Phase', 'Fluorobenzenes', 'HeLa Cells', 'Humans', 'Hydrogen-Ion Concentration', 'Phenols', 'Phosphoproteins', 'Proteomics', 'Tandem Mass Spectrometry'] | 28,555,341 | [['E05.196.181.400.300'], ['E05.196.181.400.495'], ['D02.455.426.559.389.358', 'D02.455.526.510.432'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D02.455.426.559.389.657'], ['D12.776.744'], ['H01.158.201.843', 'H01.158.273.180.350.700',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancement of red cell washout from blood clots by alteration of gel pore size and red cell flexibility. | Plasma clots formed in the presence of erythrocytes have pores large enough to allow significant perfusion induced washout of red cells. Erythrocyte washout is a function of gel pore size and erythrocyte flexibility. This study evaluated the possibility of increasing cell washout by enhancing gel pore size and/or eryth... | ['Blood Coagulation', 'Dextrans', 'Erythrocyte Deformability', 'Erythrocytes', 'Fibrin', 'Gels', 'Humans', 'Pentoxifylline'] | 1,700,633 | [['G09.188.390.150'], ['D05.750.078.562.272', 'D09.698.365.272'], ['G09.188.370.249'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D12.776.124.270'], ['D20.280.320', 'D26.255.165.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.759.758.824.651.700']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimates and predictors of health care costs of esophageal adenocarcinoma: a population-based cohort study. | BACKGROUND: Esophageal adenocarcinoma (EAC) incidence is increasing rapidly. Esophageal cancer has the second lowest 5-year survival rate of people diagnosed with cancer in Canada. Given the poor survival and the potential for further increases in incidence, phase-specific cost estimates constitute an important input f... | ['Adenocarcinoma', 'Adult', 'Aged', 'Esophageal Neoplasms', 'Female', 'Health Care Costs', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Retrospective Studies'] | 29,945,563 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E05.318.372.500.500.500', 'E05... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Challenges in conducting a randomized clinical trial of older people with chronic dizziness: before, during and after vestibular rehabilitation. | PURPOSE: This study aims to describe the process of conducting a randomized clinical trial of elderly with chronic dizziness subjected to vestibular rehabilitation (VR) and to verify its effectiveness on dizziness intensity.METHODS: Older adults (?65 years) with chronic dizziness from vestibular disorders referred to V... | ['Aged', 'Aged, 80 and over', 'Comorbidity', 'Dizziness', 'Educational Status', 'Exercise Therapy', 'Female', 'Health Status', 'Humans', 'Male', 'Postural Balance', 'Research Design'] | 25,460,341 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.225', 'N06.850.490.687'], ['C23.888.592.763.237'], ['N01.824.196'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.752', ... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Using RPE to regulate exercise intensity during a 20-week training program for postmenopausal women: a pilot study. | Feelings of effort sense quantified via the Borg Rating of Perceived Exertion (RPE) scale have been validated for regulating exercise intensity. Most studies validating RPE for exercise prescription have used young, male subjects and only a few exercise sessions. As part of a larger study we examined the accuracy of RP... | ['Aged', 'Exercise', 'Female', 'Humans', 'Perception', 'Physical Exertion', 'Pilot Projects', 'Postmenopause', 'Reproducibility of Results', 'Surveys and Questionnaires', 'Teaching'] | 15,560,361 | [['M01.060.116.100'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593'], ['G11.427.683'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['G08.686.157.500.625', 'G08.686.841.249.500.625'], ['E05.318.370.725', 'E05.337.851', 'N05.715.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector. | Salmonella typhimurium engineered to deliver cancer/testis antigen NY-ESO-1 through type III secretion (S typhimurium-NY-ESO-1) was shown to be an efficient cancer vaccine construct in mice and to stimulate NY-ESO-1-specific CD8(+)/CD4(+) T cells in vitro in patients with cancer with NY-ESO-1 spontaneous immunity. We a... | ['Antigens, Neoplasm', 'Cell Differentiation', 'Cells, Cultured', 'Genetic Vectors', 'Glucocorticoid-Induced TNFR-Related Protein', 'Humans', 'Interleukin-2 Receptor alpha Subunit', 'Interleukin-6', 'Lymphocyte Activation', 'Membrane Proteins', 'Receptors, Nerve Growth Factor', 'Receptors, Tumor Necrosis Factor', 'Salm... | 17,986,662 | [['D23.050.285'], ['G04.152'], ['A11.251'], ['G05.360.337'], ['D12.776.543.750.705.852.760.238'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.852.420.320.500'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of mouse bioassay, HPLC and enzyme immunoassay methods for determining diarrhetic shellfish poisoning toxins in mussels. | Mussel specimens (Mytilus galloprovincialis) collected from two different areas of the Adriatic Sea were analysed for diarrhoetic shellfish poisoning (DSP) toxin by three methods: mouse bioassay, the DSP Check enzyme immunoassay kit, and high-performance liquid chromatography (HPLC). The results obtained confirm that Y... | ['Animals', 'Biological Assay', 'Bivalvia', 'Chromatography, High Pressure Liquid', 'Diarrhea', 'Enzyme-Linked Immunosorbent Assay', 'Ethers, Cyclic', 'Marine Toxins', 'Mice', 'Okadaic Acid', 'Phosphoprotein Phosphatases', 'Seawater', 'Shellfish'] | 7,886,696 | [['B01.050'], ['E05.091'], ['B01.050.500.644.080'], ['E05.196.181.400.300'], ['C23.888.821.214'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D02.355.291', 'D04.345.241'], ['D23.946.580'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.355.2... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Functional assessment of infant breastfeeding patterns. | As breastfeeding rates have increased in the United States, the need has arisen for coordinated approaches to the assessment of normal and problem situations. Since some difficulties are related to the manner in which baby feeds, guidelines are discussed for the visual assessment of breastfeeding. These include the whe... | ['Breast Feeding', 'Feeding Behavior', 'Female', 'Humans', 'Infant, Newborn', 'Nursing Assessment', 'Patient Care Planning'] | 2,789,563 | [['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['N04.590.233.508.480'], ['N04.590.233.624']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The complete mitochondrial genome of the Poecilia formosa (Amazon molly). | The Amazon molly, Poecilia formosa, a member of the Poeciliidae family, is a freshwater fish reproducing through gynogenesis. The complete mitochondrial genome of the P. formosa is determined for the first time in this study. It is a circular molecule of 16 542 bp in length, including 13 protein-coding genes, 22 transf... | ['Animals', 'Base Composition', 'Genes, rRNA', 'Genome Size', 'Genome, Mitochondrial', 'Mitochondria', 'Phylogeny', 'Poecilia', 'RNA, Transfer', 'Sequence Analysis, DNA'] | 26,260,185 | [['B01.050'], ['G02.111.080'], ['G05.360.340.024.340.645.750'], ['G05.360.340.037'], ['G05.360.340.360'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.050.150.900.493.850.280.680'], ['D13.444.735.757'], ['E05.393.760.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cationic modulation of human dopamine transporter: dopamine uptake and inhibition of uptake. | Effects of cations on dopamine (DA) uptake into cells expressing the human dopamine transporter and on inhibition of DA uptake by various substrates and inhibitors were investigated by using rotating disk electrode voltammetry. The Na(+) dependence of DA uptake varied with Na(+) substitutes, hyperbolic with Li(+), almo... | ['Carrier Proteins', 'Cations, Monovalent', 'Cells, Cultured', 'Choline', 'Cocaine', 'Dopamine', 'Dopamine Plasma Membrane Transport Proteins', 'Dopamine Uptake Inhibitors', 'Electrodes', 'Humans', 'Kidney', 'Kinetics', 'Lithium', 'Membrane Glycoproteins', 'Membrane Transport Proteins', 'Metals, Alkali', 'Nerve Tissue ... | 10,454,463 | [['D12.776.157'], ['D01.248.497.300.459'], ['A11.251'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], [... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evidence supporting membrane fusion as the mechanism of myelin basic protein-induced insulin release from rat pancreatic islets. | In order to clarify insulinotropic effects of the myelin basic protein (MBP) we studied mode of association and distribution of MBP in the pancreatic islets and tested the insulin-releasing activity of various MBP peptides. Rat pancreatic islets were first stimulated in a static incubation with 10 microM bovine MBP (bM... | ['Animals', 'Cathepsin D', 'Cattle', 'Cell Survival', 'Glucagon', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Membrane Fusion', 'Myelin Basic Protein', 'Peptide Fragments', 'Rats'] | 7,492,948 | [['B01.050'], ['D08.811.277.656.074.500.180', 'D08.811.277.656.224.187', 'D08.811.277.656.300.048.180'], ['B01.050.150.900.649.313.500.380.271'], ['G04.346'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A regularized flow quantification method using MRI tagging and Single Echo Acquisition imaging. | Single Echo Acquisition (SEA) imaging is a fully parallel imaging method that can be used to image rapid flow at the frame rate as high as 200 frames per second. Previous work has shown that SEA imaging can visualize turbulent flows, and discussed a preliminary tool for quantitatively analyzing 2D rapid fluid flows usi... | ['Algorithms', 'Artifacts', 'Blood Flow Velocity', 'Contrast Media', 'Echo-Planar Imaging', 'Equipment Design', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Models, Statistical', 'Phantoms, Imaging', 'Rheology', 'Time Factors'] | 19,163,438 | [['G17.035', 'L01.224.050'], ['E05.047'], ['E01.370.370.130', 'G09.330.380.630.080'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.825.500.200'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.85... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Unbiased quantitation of Escherichia coli membrane proteome using phase transfer surfactants. | We developed a sample preparation protocol for rapid and unbiased analysis of the membrane proteome using an alimentary canal-mimicking system in which proteases are activated in the presence of bile salts. In this rapid and unbiased protocol, immobilized trypsin is used in the presence of deoxycholate and lauroylsarco... | ['Chemotaxis', 'Databases, Protein', 'Escherichia coli', 'Escherichia coli Proteins', 'Flagella', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'Membrane Proteins', 'Protein Structure, Tertiary', 'Protein Subunits', 'Proteome', 'Proteomics', 'RNA, Messenger', 'Solubility', 'Surface-Active Agents... | 19,767,571 | [['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.09... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Contrast-enhanced whole-heart coronary magnetic resonance angiography at 3.0 T: comparison with steady-state free precession technique at 1.5 T. | OBJECTIVES: To compare contrast-enhanced whole-heart coronary MR angiography (MRA) at 3.0 T and noncontrast steady-state free precession coronary MRA at 1.5 T in the same volunteers.MATERIALS AND METHODS: Nine healthy volunteers underwent both coronary MRA using 3D FLASH with slow infusion of MultiHance at 3.0 T and 3D... | ['Adult', 'Aged', 'Algorithms', 'Contrast Media', 'Coronary Angiography', 'Coronary Vessels', 'Female', 'Heart', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Angiography', 'Male', 'Meglumine', 'Middle Aged', 'Organometallic Compounds', 'Reproducibility of Results', 'Sens... | 18,708,861 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['A07.015.114.269', 'A07.015.908.194'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Inducibility of metallothionein biosynthesis in the whole soft tissue of zebra mussels Dreissena polymorpha exposed to cadmium, copper, and pentachlorophenol. | Freshwater mussels Dreissena polymorpha (Pallas, 1771) were exposed to the elevated concentrations of Cd (10, 50, 100, and 500 microg/L), Cu (10, 30, 50, and 80 microg/L), and an organochlorinated pesticide, pentachlorophenol (PCP) (1, 10, and 100 microg/L). Induced synthesis of biomarker metallothionein (MT) and chang... | ['Animals', 'Cadmium', 'Copper', 'Dose-Response Relationship, Drug', 'Dreissena', 'Environmental Exposure', 'Metallothionein', 'Pentachlorophenol', 'Pesticides', 'Toxicity Tests', 'Water Pollutants'] | 19,365,804 | [['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.500.644.080.225'], ['N06.850.460.350'], ['D12.776.556.670'], ['D02.455.426.559.389.657.190.633'], ['D27.720.031.700', 'D27.888.723'], ['E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Antiplatelet therapy in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction: a retrospective observational study of prasugrel and clopidogrel. | BACKGROUND: Primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) is a therapeutic success when supported by dual antiplatelet therapy. Prasugrel has been introduced as a potential alternative to clopidogrel alongside aspirin. We aimed to assess prasugrel versus clopid... | ['Adult', 'Aged', 'Clopidogrel', 'Electrocardiography', 'Female', 'Hospital Mortality', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Percutaneous Coronary Intervention', 'Piperazines', 'Platelet Aggregation Inhibitors', 'Prasugrel Hydrochloride', 'Proportional Hazards Models', 'Retrospective Studies', 'Th... | 24,428,852 | [['M01.060.116'], ['M01.060.116.100'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Application of UKHCDO 2004 guidelines in type 1 von Willebrand Disease--a single centre paediatric experience of the implications of altered or removed diagnosis. | Diagnosis of type I von Willebrand Disease (VWD) can be challenging. In 2004, the United Kingdom Haemophilia Centre Doctors' Organisation (UKHCDO) proposed more stringent diagnostic criteria to replace the 1995 guidelines. To determine the true number of cases of type 1 VWD in a single paediatric centre, the 2004 UKHCD... | ['Child', 'Child Health Services', 'Child, Preschool', 'Hematologic Tests', 'Humans', 'Medical History Taking', 'Practice Guidelines as Topic', 'Retrospective Studies', 'United Kingdom', 'von Willebrand Disease, Type 1', 'von Willebrand Factor'] | 21,371,186 | [['M01.060.406'], ['N02.421.143.130'], ['M01.060.406.448'], ['E01.370.225.625', 'E05.200.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.510'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Use of a third-generation perfluorocarbon for preservation of rat DCD liver grafts. | BACKGROUND: Cold storage in any of the commonly used preservation solutions is not always adequate for donation after cardiac death (DCD) liver grafts due to prolonged warm ischemic time. In this study, we used a third-generation perfluorocarbon (PFC), Oxycyte, for DCD liver graft preservation in a rat model.MATERIALS ... | ['Adenosine', 'Allopurinol', 'Animals', 'Death', 'Fluorocarbons', 'Glutathione', 'Insulin', 'Liver', 'Organ Preservation', 'Organ Preservation Solutions', 'Perfusion', 'Raffinose', 'Rats', 'Transplants'] | 21,543,088 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D03.633.100.759.160'], ['B01.050'], ['C23.550.260'], ['D02.455.526.510.435'], ['D12.644.456.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A03.620'], ['E02.792.833.660', 'E05.760.833.660'], ['D26.776.675'], ['E05.680'], ['D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pyoderma gangrenosum, rare parietal complication after colorectal surgery. | Pyoderma gangrenosum (PG) is a rare chronic destructive inflammatory skin disease characterized by the presence of nodules and pustules with progressively enlarging ulcers and orcutaneous necrosis. In most cases PG is idiopathic, but sometimes it is associated with conditions that often have vasculitis, such as gammapa... | ['Adenocarcinoma', 'Aged', 'Colectomy', 'Glucocorticoids', 'Humans', 'Male', 'Pyoderma Gangrenosum', 'Rare Diseases', 'Rectal Neoplasms', 'Rectum', 'Treatment Outcome'] | 24,742,420 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['E04.210.219'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.695.675', 'C17.800.862.675', 'C17.800.893.675'], ['C23.550.291.906'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Job satisfaction among primary health care workers in three selected local government areas in southwest Nigeria. | BACKGROUND: The primary health care system in Nigeria has been impaired by lack of dedicated workers who are willing to work in the rural areas. This study was carried out to examine factors that enhance job satisfaction among health workers in the primary health care system in Nigeria.METHOD: The study is a cross-sect... | ['Adult', 'Attitude of Health Personnel', 'Catchment Area, Health', 'Cross-Sectional Studies', 'Female', 'Humans', 'Job Satisfaction', 'Local Government', 'Male', 'Middle Aged', 'Nigeria', 'Primary Health Care', 'Rural Health Services', 'Surveys and Questionnaires', 'Workforce'] | 16,083,245 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['I01.409.700', 'N03.540.348.750'], ['M01.060.116.630'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Clinical efficacy of radical nephrectomy versus nephron-sparing surgery on localized renal cell carcinoma. | BACKGROUND: The aim of the present study was to compare the clinical efficacy of radical nephrectomy (RN) with nephron-sparing surgery (NSS) in treating patients with localized renal cell carcinoma (RCC).METHODS: The literature search was performed in PubMed, MEDLINE Springer, Elsevier Science Direct, Cochrane Library,... | ['Carcinoma, Renal Cell', 'Humans', 'Kidney Neoplasms', 'Neoplasm Recurrence, Local', 'Nephrectomy', 'Nephrons', 'Postoperative Complications', 'Treatment Outcome'] | 25,374,003 | [['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Discriminative stimulus- and open-field effects of the enantiomers of 11-hydroxy-delta-8-tetrahydrocannabinol in pigeons and gerbils. | The cannabimimetic activity of the two enantiomers of 11-hydroxy-delta-8-tetrahydrocannabinol (11-OH-delta-8-THC) was evaluated in pigeons trained to discriminate between the presence and absence of (-)-delta-9-tetrahydrocannabinol [(-)-delta-9-THC]. (-)-11-OH-Delta-8-THC exhibited cannabimimetic activity with a potenc... | ['Animals', 'Behavior, Animal', 'Cannabinoids', 'Columbidae', 'Discrimination Learning', 'Discrimination, Psychological', 'Dose-Response Relationship, Drug', 'Dronabinol', 'Gerbillinae', 'Male', 'Stereoisomerism', 'Structure-Activity Relationship'] | 8,115,412 | [['B01.050'], ['F01.145.113'], ['D02.455.849.090'], ['B01.050.150.900.248.165.150'], ['F02.463.425.280'], ['F02.463.593.257'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.849.090.810'], ['B01.050.150.900.649.313.992.635.300'], ['G02.607.445.682'], ['G02.111.830', 'G07.690.773.997']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The CD40 ligand expressed by human B cells costimulates B cell responses. | The possibility that activated B cells might express a ligand for CD40 that was of functional importance for B cell responses was examined by using highly purified human peripheral blood B cells, as well as a variety of B lymphoblastoid cell lines and hybridomas. Following stimulation with the combination of a calcium ... | ['Adult', 'Antigens, CD', 'Antigens, Differentiation, B-Lymphocyte', 'Antigens, Differentiation, T-Lymphocyte', 'B-Lymphocytes', 'Base Sequence', 'CD40 Antigens', 'CD40 Ligand', 'Cell Line', 'DNA', 'DNA, Complementary', 'Flow Cytometry', 'Humans', 'Immunoglobulins', 'Membrane Glycoproteins', 'Molecular Sequence Data', ... | 7,537,298 | [['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.051', 'D23.101.100.150'], ['D23.050.301.264.894', 'D23.101.100.894'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Effect of Molecular Weight on Sonoporation-Mediated Uptake in Human Cells. | Ultrasound-induced microbubble destruction can enhance drug delivery to cells. The molecular weight of therapeutic compounds varies significantly (from <1 kDa for small molecule drugs, to 7-15 kDa for siRNAs/miRNAs, to >1000 kDa for DNA plasmids). Therefore, the objective of this study was to determine the relationship... | ['Breast Neoplasms', 'Cell Membrane Permeability', 'Cells, Cultured', 'Dextrans', 'Female', 'Flow Cytometry', 'Fluorescein-5-isothiocyanate', 'Fluorescent Dyes', 'Humans', 'Mesoderm', 'Microbubbles', 'Molecular Weight', 'Myocardium', 'Sonication'] | 30,274,682 | [['C04.588.180', 'C17.800.090.500'], ['G03.143.335', 'G04.175'], ['A11.251'], ['D05.750.078.562.272', 'D09.698.365.272'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D02.455.426.779.347.400',... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnosis delay and duration of hospitalisation of patients with Buruli ulcer in Nigeria. | BACKGROUND: Delayed diagnosis of Buruli ulcer can worsen clinical presentation of the disease, prolong duration of management, and impose avoidable additional costs on patients and health providers. We investigated the profile, delays in diagnosis, duration of hospitalisation, and associated factors among patients with... | ['Adolescent', 'Adult', 'Buruli Ulcer', 'Child', 'Delayed Diagnosis', 'Female', 'Health Care Costs', 'Health Expenditures', 'Health Knowledge, Attitudes, Practice', 'Health Services Accessibility', 'Hospitalization', 'Humans', 'Length of Stay', 'Male', 'Mycobacterium ulcerans', 'Nigeria', 'Polymerase Chain Reaction', '... | 27,777,282 | [['M01.060.057'], ['M01.060.116'], ['C01.150.252.410.040.552.475.247', 'C17.800.893.295'], ['M01.060.406'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['N03.219.151.400', 'N05.300.375'], ['N03.219.151.450', 'N05.300.385'], ['F01.100.150.500', 'N05.300.150.410'], ['N04.590.374.350', 'N05.300.430'], ['E02.760.400', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Clinical implications of cervical lymph node metastasis patterns in thoracic esophageal cancer. | OBJECTIVE: The authors attempt to clarify the clinical implications of cervical lymph node metastases from thoracic esophageal cancers.SUMMARY BACKGROUND DATA: Cervical lymph node metastases from thoracic esophageal cancer have been considered to be incompatible with curative resection. However, recent studies have dem... | ['Adult', 'Aged', 'Esophageal Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neck', 'Prevalence', 'Survival Rate', 'Thorax'] | 7,986,145 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release. | Muscarinic receptors represent a promising therapeutic target for schizophrenia, but the mechanisms underlying the antipsychotic efficacy of muscarinic modulators are not well understood. Here, we report that activation of M4 receptors on striatal spiny projection neurons results in a novel form of dopaminergic regulat... | ['Allosteric Regulation', 'Animals', 'Antipsychotic Agents', 'Corpus Striatum', 'Dopamine', 'Lipoprotein Lipase', 'Mice, Knockout', 'Muscarinic Agonists', 'Oxotremorine', 'Prepulse Inhibition', 'Pyridazines', 'Receptor, Cannabinoid, CB2', 'Receptor, Muscarinic M4', 'Thiophenes'] | 27,618,677 | [['G02.111.044'], ['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D08.811.277.352.100.430'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in energy metabolism in relation to physical activity due to fermentable carbohydrates in group-housed growing pigs. | Fermentable nonstarch polysaccharides (dietary fiber) affect energy retention in group-housed growing pigs by reducing physical activity. This study assessed the effects of fermentation and bulkiness of dietary carbohydrates on physical activity in relation to energy metabolism. Eight clusters of 14 pigs were fed one o... | ['Animal Feed', 'Animals', 'Dietary Carbohydrates', 'Dietary Supplements', 'Energy Metabolism', 'Female', 'Fermentation', 'Male', 'Swine', 'Zea mays'] | 10,641,874 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['G07.203.300.456', 'J02.500.456'], ['G03.295'], ['G02.111.158.249', 'G03.191.249'], ['B01.050.150.900.649.313.500.880'], ['B01.650.940.800.575.912.250.822.966']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Plasma fibrin clot properties affect blood loss after surgical aortic valve replacement for aortic stenosis. | OBJECTIVES: Cardiac surgery is associated with elevated bleeding risk. We sought to study whether fibrin clot phenotype influences postoperative blood loss after surgery for aortic stenosis (AS).METHODS: We studied 77 isolated AS patients, including 62 who underwent aortic valve replacement and 15 who underwent the Ben... | ['Aged', 'Aortic Valve', 'Aortic Valve Stenosis', 'Cohort Studies', 'Female', 'Fibrin', 'Fibrin Clot Lysis Time', 'Fibrinogen', 'Fibrinolysis', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Middle Aged', 'Postoperative Hemorrhage'] | 30,063,794 | [['M01.060.116.100'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D12.776.124.270'], ['E01.370.225.625.265', 'E05.200.625.265', 'G09.188.315'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Abnormal dispersion of a purkinje cell subset in the mouse mutant cerebellar deficient folia (cdf). | Purkinje cells of different molecular phenotypes subdivide the cortex of the cerebellum both rostrocaudally into parasagittal bands and mediolaterally into transverse zones. Superimposed on the Purkinje cell compartmentation, the cerebellar cortex is pleated into a reproducible array of lobes and lobules. During cerebe... | ['Animals', 'Cell Count', 'Cell Movement', 'Cerebellum', 'Choristoma', 'Homozygote', 'Mice', 'Mice, Neurologic Mutants', 'Morphogenesis', 'Nerve Tissue Proteins', 'Phenotype', 'Purkinje Cells'] | 11,413,545 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.198', 'G07.568.500.180'], ['A08.186.211.132.810.428.200'], ['C23.300.250'], ['G05.380.554'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.480'], ['G07.345.500'], ['D12.776.631'], ['G05... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Variation of different carbon sources in the sewage treatment process]. | The biodegradability and speciation of organics were studied through long-term analysis of A2/O treatment. The majority of the organic matters were particle organics which accounted for 61% of the total organics. The proportions of rapidly degradable, slowly degradable and refractory organics were 15. 8% , 54. 2% and 3... | ['Biodegradation, Environmental', 'Bioreactors', 'Carbon', 'Fermentation', 'Hydrolysis', 'Sewage', 'Waste Disposal, Fluid'] | 25,518,663 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.115', 'J01.897.120.115'], ['D01.268.150'], ['G02.111.158.249', 'G03.191.249'], ['G02.380'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Processing of pseudorabies virus glycoprotein gII. | The glycoprotein complex gII of pseudorabies virus was isolated by immunoprecipitation with the monoclonal antibody M5, which was covalently linked to protein A-Sepharose. After sodium dodecyl sulfate-polyarylamide gel electrophoresis under reducing conditions and blotting onto poly(vinylidene difluoride) membrane, its... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antigen-Antibody Complex', 'Blotting, Western', 'Cell Line', 'Chromatography, Affinity', 'Genes, Viral', 'Herpesvirus 1, Suid', 'Molecular Sequence Data', 'Molecular Weight', 'Viral Envelope Proteins'] | 2,159,568 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of acepromazine on the incidence of vomiting associated with opioid administration in dogs. | OBJECTIVE: To evaluate the anti-emetic properties of acepromazine in dogs receiving opioids as pre-anesthetic medication.STUDY DESIGN: Randomized prospective clinical study.ANIMALS: One hundred and sixteen dogs (ASA I or II), admitted for elective surgical procedures. The dogs were a mixed population of males and femal... | ['Acepromazine', 'Analgesics, Opioid', 'Anesthesia', 'Animals', 'Antiemetics', 'Dogs', 'Female', 'Male', 'Preanesthetic Medication', 'Prospective Studies', 'Treatment Outcome', 'Vomiting'] | 14,756,752 | [['D02.886.369.029', 'D03.633.300.783.029'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E03.155'], ['B01.050'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['E... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A method for locating embedded left anterior descending coronary arteries. | Intraoperative detection of deeply embedded coronary arteries is difficult. This study describes an effective method to identify embedded coronary arteries by intraoperative cine angiography. Two embedded left anterior descending coronary arteries were successfully identified by intraoperative cine angiography. We beli... | ['Cardiac Surgical Procedures', 'Cineangiography', 'Coronary Angiography', 'Coronary Artery Disease', 'Coronary Vessels', 'Humans', 'Monitoring, Intraoperative', 'Reproducibility of Results'] | 23,272,867 | [['E04.100.376', 'E04.928.220'], ['E01.370.350.700.060.190', 'E01.370.370.050.190'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cytokine release syndrome after allogeneic stem cell transplantation with posttransplant cyclophosphamide. | Cytokine release syndrome (CRS) is a systemic inflammatory response with aberrant immune activation and immune hyperstimulation, that leads to increased cytokine levels and inflammation. CRS has been described after antibody and cellular-based therapies. The use of posttransplant cyclophosphamide (PTCy) as graft-vs-hos... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Agents, Alkylating', 'Antineoplastic Combined Chemotherapy Protocols', 'Combined Modality Therapy', 'Cyclophosphamide', 'Cytokine Release Syndrome', 'Female', 'Follow-Up Studies', 'Graft vs Host Disease', 'Hematologic Neoplasms', 'Hematopoietic Stem Cell Transplantation',... | 32,592,410 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['C23.550.470.790.250', 'C23.550.835.900.356'], ['E05.318.372.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Application of micro-attenuated total reflectance infrared spectroscopy to quantitative analysis of optical fiber coatings: effects of optical contact. | Micro-attenuated total reflectance (ATR) infrared spectroscopy is one of the few methods applicable for an in situ analysis of polymer coatings. In this method, the information is collected using an internal reflection element (IRE), which is brought into contact with the coated substrate. Perfect optical contact is ha... | ['Absorption', 'Algorithms', 'Equipment Failure Analysis', 'Fiber Optic Technology', 'Materials Testing', 'Microchemistry', 'Optical Fibers', 'Polymers', 'Spectrophotometry, Infrared'] | 16,454,908 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['G17.035', 'L01.224.050'], ['E05.325.192'], ['H01.671.617.249'], ['E05.570'], ['E05.196.620', 'H01.181.650'], ['E07.632.750'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.196.712.726.676', 'E05.196.867.826.676']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings. | The HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) constitute a large and structurally diverse set of compounds, several of which are currently used in the treatment of AIDS. A series of novel alkenyldiarylmethanes (ADAMs) were designed and synthesized as part of an ongoing investigation to replace the ... | ['Animals', 'Anti-HIV Agents', 'Benzoxazoles', 'Cell Line', 'Crystallography, X-Ray', 'Drug Design', 'HIV-1', 'HIV-2', 'Humans', 'In Vitro Techniques', 'Isoxazoles', 'Methane', 'Microbial Sensitivity Tests', 'Models, Molecular', 'Molecular Structure', 'Protein Conformation', 'Rats', 'Reverse Transcriptase Inhibitors', ... | 16,321,539 | [['B01.050'], ['D27.505.954.122.388.077.088'], ['D03.633.100.221'], ['A11.251.210'], ['E05.196.309.742.225'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B04.820.650.589.650.350.400'], ['B04.820.650.589.650.350.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D03.383.129.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of proximal coronary occlusion in acute coronary syndrome: a feasibility study using computerized electrocardiographic analysis. | BACKGROUND: Rapid identification of a proximal occlusion site of a major coronary artery is of paramount importance in the care of myocardial infarction (MI). It is increasingly recognized that routine electrocardiogram (ECG) can be used for that purpose, provided that expert interpretation is available. Computer-based... | ['Acute Coronary Syndrome', 'Algorithms', 'Coronary Stenosis', 'Electrocardiography', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Sensitivity and Specificity', 'Signal Processing, Computer-Assisted'] | 17,970,955 | [['C14.280.647.124', 'C14.907.585.124'], ['G17.035', 'L01.224.050'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800', 'E05.318... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Interaction of paclitaxel (Taxol) and irradiation. In-vitro differences between tumor and fibroblastic cells. | AIM: Optimal dose and schedule of paclitaxel in combined drug-irradiation treatment could not be determined for most of tumors yet. The aim of this study was to compare in vitro cytotoxicity and radiosensitizing abilities as a function of single paclitaxel (Taxol) exposure in tumor and fibroblastic cells using differen... | ['Adenocarcinoma', 'Animals', 'Antineoplastic Agents, Phytogenic', 'Cell Survival', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Dose-Response Relationship, Radiation', 'Fibroblasts', 'Flow Cytometry', 'Glioblastoma', 'Humans', 'Lung Neoplasms', 'Paclitaxel', 'Particle Accelerators', 'Radiation-Sensitizing A... | 10,230,460 | [['C04.557.470.200.025'], ['B01.050'], ['D27.505.954.248.179'], ['G04.346'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['A11.329.228'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.5... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development. | BACKGROUND: Mutations in the LGI1 gene predispose to a rare, hereditary form of temporal epilepsy. Currently, little is known about the temporal and spatial expression pattern of Lgi1 during normal embryogenesis and so to define this more clearly we used a transgenic mouse line that expresses GFP under the control of L... | ['Animals', 'Brain', 'Eye', 'Gene Expression Regulation, Developmental', 'Intracellular Signaling Peptides and Proteins', 'Mice', 'Mice, Transgenic', 'Proteins', 'Tongue'] | 21,569,517 | [['B01.050'], ['A08.186.211'], ['A01.456.505.420', 'A09.371'], ['G05.308.310'], ['D12.644.360', 'D12.776.476'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['D12.776'], ['A03.556.500.885', 'A14.549.885']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human neutrophils exhibit disparate chemotactic factor gene expression. | The evolution of acute inflammation from initiation through resolution is associated with the changing character of the infiltrating leukocytes. Recruitment of these leukocytes is dependent upon the generation of chemotactic factors that have either global or specific activity for a particular leukocyte. In this manusc... | ['Acute Disease', 'Base Sequence', 'Chemokine CCL2', 'Chemotactic Factors', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Gene Expression', 'Humans', 'Inflammation', 'Interleukin-8', 'Lipopolysaccharides', 'Molecular Sequence Data', 'Neutrophils', 'RNA, Messenger'] | 1,701,991 | [['C23.550.291.125'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D23.125'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170',... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Migration inhibitory factor related protein-8 (MRP-8) is an autocrine chemotactic factor for periodontal ligament cells. | Previous studies have suggested that human periodontal ligament (PDL) cells secrete a chemotactic factor which stimulates motility in an autocrine manner. Here we report the partial amino acid sequence of a purified factor which shows 100% homology with human migration inhibitory factor related protein-8 (MRP-8). In ad... | ['Amino Acid Sequence', 'Antigens, Differentiation', 'Autocrine Communication', 'Calcium-Binding Proteins', 'Calgranulin A', 'Cell Movement', 'Cells, Cultured', 'Chemotactic Factors', 'Epidermal Growth Factor', 'Humans', 'Insulin-Like Growth Factor I', 'Insulin-Like Growth Factor II', 'Macrophage Migration-Inhibitory F... | 10,371,249 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.301.264', 'D23.101.100'], ['G04.085.100'], ['D12.776.157.125'], ['D12.776.157.125.750.500.100', 'D12.776.631.655.500.100', 'D23.050.301.562.100'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['D23.125'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Genetic markers among three population groups of Hungary. | Three ethnic groups from Hungary, the general population of Hungary, the Matyo and the Gypsies, were examined with respect to the genetic markers PGP, GLO1, GPT, ACP1, ESD, PGD, ADA, AK1, PGM1 subtypes, C3, BF, HP, GC subtypes, PI, TF subtypes and AMY2. Significant variations were noted for the gene frequencies of GPT ... | ['Adult', 'Blood Proteins', 'Enzymes', 'European Continental Ancestry Group', 'Female', 'Gene Frequency', 'Genetic Markers', 'Humans', 'Male', 'Middle Aged', 'Phenotype'] | 3,154,113 | [['M01.060.116'], ['D12.776.124'], ['D08.811'], ['M01.686.508.400'], ['G05.330'], ['D23.101.387', 'G05.695.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.695']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The beneficial influence of prior knowledge on the quantitation of in vivo magnetic resonance spectroscopy signals. | RATIONALE AND OBJECTIVES: This work concerns quantitation of in vivo magnetic resonance spectroscopy signals and the influence of prior knowledge on the precision of parameter estimates. The authors point out how prior knowledge can be used for experiments.METHODS: The Cramer-Rao lower bounds formulae of the noise-rela... | ['Adenosine Triphosphate', 'Animals', 'Brain', 'Least-Squares Analysis', 'Magnetic Resonance Spectroscopy', 'Mathematics', 'Rats', 'Rats, Wistar', 'Signal Processing, Computer-Assisted'] | 10,084,671 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A08.186.211'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['E05.196.867.519'], ['H01.548'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['L... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Magnetic resonance tomography in hepatocellular carcinoma and idiopathic hemochromatosis]. | A case of hepatocellular carcinoma in idiopathic hemochromatosis is discussed to illustrate the possible advantages of MR imaging. Since hepatic iron overload provides a natural source of paramagnetic contrast enhancement MRI should performed in preference to other investigative procedures to detect small and curative ... | ['Carcinoma, Hepatocellular', 'Hemochromatosis', 'Humans', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged'] | 2,175,039 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C16.320.565.618.337', 'C18.452.565.500.480', 'C18.452.648.618.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E01.370.350.825.500'], ['M01.060.116.630']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Reversal effect of matrine on drug resistance of human nasopharyngeal carcinoma cell line]. | OBJECTIVE: To study the reversal effect of matrine and its derivatives on drug resistance of human nasopharyngeal carcinoma cell line HONE1/DDP.METHODS: The drug-resistant cell line was established by the human nasopharyngeal carcinoma cells HONE1 with gradually increasing concentration of cisplatin. The matrine and it... | ['Alkaloids', 'Antineoplastic Agents', 'Apoptosis', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Cisplatin', 'Drug Resistance, Neoplasm', 'Drug Screening Assays, Antitumor', 'Humans', 'Molecular Structure', 'Multidrug Resistance-Associated Proteins', 'Nasopharyngeal Neoplasms', 'Quinolizines', 'Sophora', 'b... | 23,705,367 | [['D03.132'], ['D27.505.954.248'], ['G04.146.954.035'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G07.690.773.984.395'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two cases of anaphylaxis after laminaria insertion. | Anaphylaxis following laminaria insertion rarely occurs but may be a life-threatening condition. Laminaria tents, prepared from natural sea kelp, are commonly used prior to elective termination of pregnancy to achieve cervical dilatation. We report herein two cases of anaphylaxis caused by IgE-mediated hypersensitivity... | ['Adult', 'Anaphylaxis', 'Diagnosis, Differential', 'Female', 'Humans', 'Hypersensitivity, Immediate', 'Laminaria', 'Pregnancy', 'Skin Tests'] | 14,676,449 | [['M01.060.116'], ['C20.543.480.099'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480'], ['B01.750.600.425.500'], ['G08.686.784.769'], ['E01.370.225.812.871', 'E05.200.812.871', 'E05.478.594.890']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Capnographic monitoring of midazolam and propofol sedation during ERCP: a randomized controlled study (EndoBreath Study). | BACKGROUND AND STUDY AIMS: This was to determine whether intervention based on additional capnographic monitoring reduces the incidence of hypoxemia during midazolam and propofol sedation for endoscopic retrograde cholangiopancreatography (ERCP).METHODS: Patients (American Society of Anesthesiologists [ASA] I – IV) sch... | ['Adult', 'Aged', 'Aged, 80 and over', 'Capnography', 'Cholangiopancreatography, Endoscopic Retrograde', 'Conscious Sedation', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Hypoxia', 'Incidence', 'Intention to Treat Analysis', 'Male', 'Midazolam', 'Middle Aged', 'Monitoring, Physiologic', 'Outcome and Process Assessm... | 26,415,090 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.386.700.150'], ['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['E03.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms. | The human antibody response to flavivirus infection is dominantly directed against a cross-reactive epitope on the fusion loop of domain II (DII-FL) of the envelope (E) protein. Although antibodies against this epitope fail to recognize fully mature West Nile virus (WNV) virions and accordingly neutralize infection poo... | ['Animals', 'Antibodies, Neutralizing', 'Antibodies, Viral', 'Complement System Proteins', 'Cross Reactions', 'Disease Models, Animal', 'Immunization, Passive', 'Mice', 'Mice, Inbred C57BL', 'Phagocytosis', 'Receptors, IgG', 'Rodent Diseases', 'Survival Analysis', 'Viral Envelope Proteins', 'West Nile virus'] | 21,917,960 | [['B01.050'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D12.776.124.486.274'], ['G12.122.281'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.095.465.425.400.330',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cystoid macular edema after femtosecond laser-assisted versus phacoemulsification cataract surgery. | PURPOSE: To evaluate the incidence of postoperative clinical cystoid macular edema (CME) associated with femtosecond laser-assisted cataract surgery (Catalys laser system) versus phacoemulsification cataract surgery.SETTING: Launceston Eye Institute, Launceston, Tasmania, Australia.DESIGN: Nonrandomized, single-surgeon... | ['Aged', 'Aged, 80 and over', 'Cataract Extraction', 'Female', 'Fluorescein Angiography', 'Humans', 'Incidence', 'Laser Therapy', 'Macular Edema', 'Male', 'Middle Aged', 'Phacoemulsification', 'Postoperative Complications', 'Prospective Studies', 'Tomography, Optical Coherence'] | 26,703,485 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.540.825.249'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E02.594', 'E04.014.520'], ['C11.768.585.439... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy of porcine factor VIII in the management of haemophiliacs with inhibitors. | We report our experience with polyelectrolyte-fractionated highly purified porcine factor VIII concentrate (Hyate:C). Porcine factor VIII concentrate was used to treat 14 haemorrhagic episodes including seven severe haemarthroses, three severe haematomata, two episodes of oral bleeding, one traumatic and the other afte... | ['Animals', 'Child', 'Child, Preschool', 'Factor VIII', 'Hemophilia A', 'Humans'] | 6,440,588 | [['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fatal thrombo-embolic complications at aorto-femoral angiography. | Fatal complications due to angiographic procedures are rare. An awareness of these complications is, however, mandatory in order to be able to prevent them. This report concerns three fatal cases with a deleterious complication of distal macro- and microembolization in connection with the angiographic procedure. In all... | ['Aged', 'Angiography', 'Aortic Diseases', 'Aortography', 'Arterial Occlusive Diseases', 'Femoral Artery', 'Humans', 'Male', 'Microcirculation', 'Middle Aged', 'Thromboembolism'] | 3,976,418 | [['M01.060.116.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C14.907.109'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['C14.907.137'], ['A07.015.114.351'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.330.100.645'], ['M01.060.116.630'], ['C14.907.355.590']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. | OBJECTIVE: Previous studies demonstrated increased levels of cysteine proteases cathepsins in serum and adipose tissues from obese patients. We now provide evidence from a mouse model of obesity to suggest a direct participation of cathepsin K (CatK) in mouse body weight gain and glucose metabolism.METHODS AND RESULTS:... | ['3T3-L1 Cells', 'Adipocytes', 'Adipogenesis', 'Animals', 'Blood Glucose', 'Cathepsin K', 'Cathepsins', 'Cells, Cultured', 'Cysteine Proteinase Inhibitors', 'Female', 'Fibronectins', 'Glucose', 'Humans', 'Insulin', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mice, Obese', 'Weight Gain'] | 18,818,416 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['G04.152.149'], ['B01.050'], ['D09.947.875.359.448.500'], ['D08.811.277.656.224.405', 'D08.811.277.656.262.500.156', 'D08.811.277.656.300.200.156'], ['D08.811.277.656.224'], ['A11.251'], ['D27.505.519.389.745.325'], ['D12.776.377.715.390', 'D12.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide-dependent Akt and Rab5 modulation. | Keratins (Ks) are epithelial cell intermediate filament (IF) proteins that are expressed as pairs in a differentiation-regulated manner. Hepatocyte IFs are made only of K8/K18 pairs, which means that a K8 loss in K8-null mice leads to degradation of K18. Functionally, there is accumulating evidence that IFs contribute ... | ['Animals', 'Hepatocytes', 'Keratin-18', 'Keratin-8', 'Mice', 'Mice, Knockout', 'Phosphatidylinositol 3-Kinases', 'Phosphatidylinositols', 'Protein Transport', 'Proto-Oncogene Proteins c-akt', 'Receptor, Insulin', 'Signal Transduction', 'Vesicular Transport Proteins', 'rab5 GTP-Binding Proteins'] | 28,442,548 | [['B01.050'], ['A11.436.348'], ['D05.750.078.593.450.300.800', 'D12.776.220.475.450.300.800', 'D12.776.860.607.300.800'], ['D05.750.078.593.450.600.800', 'D12.776.220.475.450.600.800', 'D12.776.860.607.650.800'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.5... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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