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Nasal videoendoscopy in prosthetic management of palatopharyngeal dysfunction. | Application of nasal videoendoscopic procedures simplifies and objectifies design of an obturator prosthesis. Although oral videoendoscopic techniques are also valuable, the nasal perspective provides valuable information not visible from the oral perspective. Because the primary function of the obturator prosthesis is... | ['Endoscopes', 'Endoscopy', 'Equipment Design', 'Fiber Optic Technology', 'Humans', 'Nose', 'Palatal Obturators', 'Speech Disorders', 'Velopharyngeal Insufficiency', 'Video Recording'] | 3,478,481 | [['E07.230.220', 'E07.858.240'], ['E01.370.388.250', 'E04.502.250'], ['E05.320'], ['H01.671.617.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.456.505.733', 'A04.531', 'A09.531'], ['E06.780.346.850', 'E07.695.190.600'], ['C10.597.606.150.500.800', 'C23.888.592.604.150.500.800'], ['C07.465.525.955', 'C07.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Keratoconus, the most common corneal dystrophy. Can keratoplasty be avoided?]. | Keratoconus is the most common form of corneal dystrophy. It consists of a non inflammatory progressive thinning process that leads to conical ectasia of the cornea, causing high myopia and astigmatism. In more advanced cases, opacities can be seen at the apex of the cone. Traditional conservative management of keratoc... | ['Contact Lenses', 'Corneal Stroma', 'Corneal Transplantation', 'Eyeglasses', 'Humans', 'Keratoconus'] | 22,039,707 | [['E07.632.500.276'], ['A09.371.060.217.228'], ['E02.095.147.725.225', 'E04.540.825.374', 'E04.936.580.225'], ['E07.632.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.204.627']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-cell-density cultivation of Pseudomonas putida IPT 046 and medium-chain-length polyhydroxyalkanoate production from sugarcane carbohydrates. | We studied high-density cultures of Pseudomonas putida IPT 046 for the production of medium-chain-length polyhydroxyalkanoates (PHAMCL) using an equimolar mixture of glucose and fructose as carbon sources. Kinetics studies of P. putida growth resulted in a maximum specific growth rate of 0.65 h(-1). Limitation and inhi... | ['Bioreactors', 'Carboxylic Acids', 'Cell Culture Techniques', 'Fructose', 'Glucose', 'Plant Extracts', 'Pseudomonas putida', 'Quaternary Ammonium Compounds', 'Saccharum'] | 15,496,728 | [['E07.115', 'J01.897.120.115'], ['D02.241'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D09.947.875.359.448'], ['D20.215.784.500', 'D26.667'], ['B03.440.400.425.625.625.675', 'B03.660.250.580.590.580'], ['D01.625.062.500', 'D02.092.87... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Investigating the association between body fat and depression via Mendelian randomization. | Obesity and depression are major public health concerns that are both associated with substantial morbidity and mortality. There is a considerable body of literature linking obesity to the development of depression. Recent studies using Mendelian randomization indicate that this relationship is causal. Most studies of ... | ['Adipose Tissue', 'Adult', 'Aged', 'Body Mass Index', 'Depressive Disorder', 'Female', 'Genome-Wide Association Study', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Mendelian Randomization Analysis', 'Middle Aged', 'Obesity', 'Polymorphism, Single Nucleotide', 'Risk Factors'] | 31,383,844 | [['A10.165.114'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['F03.600.300'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Incidence of portal vein thrombosis complicating liver metastasis as detected by duplex ultrasound. | In a prospective study of 100 patients with liver metastasis using real-time ultrasound, 8 patients (8%) were found to have portal vein thrombosis (PVT). Sixty seven of these patients, which included all with PVT, also underwent duplex examination. Pulsed Doppler showed absent flow in 4 of 8 patients, indicating comple... | ['Adult', 'Aged', 'Aged, 80 and over', 'Collateral Circulation', 'Female', 'Humans', 'Incidence', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Portal Vein', 'Prospective Studies', 'Regional Blood Flow', 'Thrombosis', 'Ultrasonography', 'Vascular Patency'] | 2,188,009 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G09.330.100.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pancreatic arteriovenous malformation perforated into the common bile and pancreatic ducts:a case report]. | A 54-year-old man presented with melena and was conservatively monitored for duodenitis. He developed epigastric pain, and dynamic computed tomography revealed abnormal blood flow in the pancreatic head. The endoscopic retrograde cholangiography revealed that the common bile and pancreatic ducts were simultaneously enh... | ['Arteriovenous Malformations', 'Bile', 'Common Bile Duct', 'Humans', 'Male', 'Middle Aged', 'Pancreas', 'Pancreatic Ducts', 'Pancreaticoduodenectomy'] | 30,416,153 | [['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['A12.200.087'], ['A03.159.183.079.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A03.734'], ['A03.734.667'], ['E04.210.760']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dark Adaptation in Patients with Primary Open-Angle Glaucoma, Pseudoexfoliation Glaucoma and Childhood Glaucoma. | Purpose To investigate the state of dark adaptation and macular blood flow in different forms of glaucoma. Methods Eighteen eyes of 18 patients with primary open-angle glaucoma, 14 eyes of 14 patients with pseudoexfoliation glaucoma, and 10 eyes of 10 patients with childhood glaucoma (CG) were examined by means of dark... | ['Dark Adaptation', 'Exfoliation Syndrome', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Male', 'Middle Aged', 'Vision Disorders', 'Visual Acuity', 'Visual Field Tests', 'Visual Fields'] | 28,142,162 | [['G14.020.371'], ['C11.941.375.285'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.751.941', 'C11.966', 'C23.888.592.763.941'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940'], ['E01.370.380.850.962'], ['F02.463.593.932.934', 'G14.950']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of precore and core promoter mutations on hepatic histology in patients with chronic hepatitis B. | BACKGROUND: The details of liver histology of patients with precore and core promoter mutations are still not clear.AIM: To determine the role of precore and core promoter mutations in liver histology in Chinese patients with chronic hepatitis B.PATIENTS AND METHODS: Intrahepatic hepatitis B virus DNA (by COBAS Amplico... | ['Adult', 'Aged', 'DNA, Viral', 'Female', 'Hepatitis B Core Antigens', 'Hepatitis B e Antigens', 'Hepatitis B, Chronic', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Mutation', 'Promoter Regions, Genetic'] | 16,097,996 | [['M01.060.116'], ['M01.060.116.100'], ['D13.444.308.568'], ['D23.050.327.495.500.450'], ['D23.050.327.495.500.469'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Fluoxetine for trichotillomania: an open clinical trial. | Of 17 adult patients with long-standing trichotillomania, 13 completed an 8- to 12-week open trial of fluoxetine, up to 80 mg per day. No patient had obsessive-compulsive disorder or major depression. We used the compulsions subscale of the Yale-Brown Obsessive-Compulsive Scale (YBOCS) to rate patients' hair-pulling be... | ['Adult', 'Aged', 'Female', 'Fluoxetine', 'Humans', 'Male', 'Middle Aged', 'Trichotillomania'] | 1,513,916 | [['M01.060.116'], ['M01.060.116.100'], ['D02.092.831.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.250.800']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells. | We formerly demonstrated that vaccination with Wilms' tumor 1 (WT1)-loaded autologous monocyte-derived dendritic cells (mo-DCs) can be a well-tolerated effective treatment in acute myeloid leukemia (AML) patients. Here, we investigated whether we could introduce the receptor for hyaluronic acid-mediated motility (RHAMM... | ['Antigen Presentation', 'Antigens, Neoplasm', 'Cancer Vaccines', 'Dendritic Cells', 'Electroporation', 'Extracellular Matrix Proteins', 'Gene Expression', 'HLA-A Antigens', 'Humans', 'Hyaluronan Receptors', 'Immunotherapy', 'Leukemia, Myeloid, Acute', 'Neoplasms', 'RNA, Messenger', 'T-Lymphocytes'] | 27,659,531 | [['G12.119', 'G12.450.050.400.070'], ['D23.050.285'], ['D20.215.894.200'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['D12.776.860.300'], ['G05.297'], ['D12.776.395.550.489.400', 'D12.776.543.550.439.400', 'D23.050.301.500.100.400', 'D23.050... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Partial nephrectomy. | Partial nephrectomy has a place in the management of renal calculous disease. It should be limited, however, only to patients in whom calculi or calcareous material are both demonstrable and inaccessible by any other means or to patients in whom there are discrete areas of distortion, dilatation, or disease predisposin... | ['History, 19th Century', 'History, 20th Century', 'Humans', 'Kidney Calculi', 'Nephrectomy'] | 6,356,551 | [['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], ['E04.950.774.435']] | ['Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel substrate specificity of D-arabinose isomerase from Klebsiella pneumoniae and its application to production of D-altrose from D-psicose. | d-Arabinose isomerase from Klebsiella pneumoniae 40bXX was purified 12-fold with a 62.5% yield indicated by its electrophoretic homogeneity. The purified enzyme showed the highest activities toward d-arabinose and l-fucose as substrates at optimum conditions (50 mM glycine-NaOH, pH 9.0, 40 degrees C). The enzyme had a ... | ['Aldose-Ketose Isomerases', 'Fructose', 'Hexoses', 'Klebsiella pneumoniae', 'Substrate Specificity'] | 17,189,171 | [['D08.811.399.475.200'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D09.947.875.359'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions between the complement and endothelin systems in normal pregnancy and following placental ischemia. | Preeclampsia is characterized by new onset hypertension and fetal growth restriction and is associated with aberrant activation of the innate immune complement system and stressed or ischemic placenta. Previous studies have suggested a role for both endothelin and complement system activation products in new onset hype... | ['Animals', 'Cell Line', 'Complement Activation', 'Complement System Proteins', 'Disease Models, Animal', 'Endothelins', 'Female', 'Ischemia', 'Placenta', 'Pre-Eclampsia', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Uterus', 'Vascular Endothelial Growth Factor A'] | 31,326,653 | [['B01.050'], ['A11.251.210'], ['G12.274'], ['D12.776.124.486.274'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['C23.550.513'], ['A16.710'], ['C13.703.395.249'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.63... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stereotactic body radiotherapy for colorectal cancer liver metastases: A systematic review. | INTRODUCTION: While surgery is the preferred option for isolated, operable liver metastases from colorectal cancer (CRC), ablative techniques are endorsed for medically or technically inoperable lesions. Stereotactic body radiotherapy (SBRT) is an alternative ablative local therapy that delivers high RT doses in a few ... | ['Adult', 'Colorectal Neoplasms', 'Epidemiologic Methods', 'Humans', 'Liver Neoplasms', 'Radiosurgery', 'Treatment Outcome'] | 29,997,034 | [['M01.060.116'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E02.815.530', 'E04.525.800.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
State-level estimates of the economic costs of alcohol and drug abuse. | Substance abuse (SA) imposes a substantial economic burden on society. This burden arises largely from indirect costs associated with lost productivity (morbidity), premature mortality, and crime. The economic impact of SA has been estimated on a national level, but state-level estimates, needed for resource allocation... | ['Adolescent', 'Adult', 'Aged', 'Alcoholism', 'Child', 'Child, Preschool', 'Cost of Illness', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'State Government', 'Substance-Related Disorders', 'United States', 'Young Adult'] | 23,614,269 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C25.775.100.250', 'F03.900.100.350'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['I01.40... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[A study of factors affecting the efficiency of electrofusion of enucleated eggs and cell-donors of nuclei]. | We studied the capacity of rabbit oocytes for electrofusion with morula blastomeres and fetal fibroblasts. The morula blastomeres fused with aging ooplasts more readily than the fetal fibroblasts: 92.9 versus 63.0%, p < 0.001. The fetal fibroblasts fused with young enucleated oocytes more efficiently than with the agin... | ['Animals', 'Blastomeres', 'Cell Fusion', 'Cell Nucleus', 'Cells, Cultured', 'Electrophysiology', 'Female', 'Fibroblasts', 'Oocytes', 'Rabbits'] | 11,969,068 | [['B01.050'], ['A11.872.700.250.130', 'A16.094'], ['E05.242.307', 'G04.155'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['H01.158.344.528', 'H01.158.782.236'], ['A11.329.228'], ['A05.360.490.690.680', 'A11.497.497.600'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased myostatin activity and decreased myocyte proliferation in chronic alcoholic cardiomyopathy. | BACKGROUND: Apoptosis mediates in alcohol-induced heart damage leading to cardiomyopathy (CMP). Myocyte proliferation may compensate for myocyte loss. Myostatin is upregulated after cardiac damage and by alcohol consumption thereby decreasing myocyte renewal. We assess the potential role of alcohol in inducing myocyte ... | ['Adult', 'Aged', 'Alcoholism', 'Cardiomyopathy, Alcoholic', 'Cell Proliferation', 'Chronic Disease', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Myocardium', 'Myocytes, Cardiac', 'Myostatin', 'Up-Regulation'] | 21,463,333 | [['M01.060.116'], ['M01.060.116.100'], ['C25.775.100.250', 'F03.900.100.350'], ['C14.280.238.057', 'C25.775.100.087.250'], ['G04.161.750', 'G07.345.249.410.750'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750']... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The DNA-binding site of the RecA protein. Photochemical cross-linking of Tyr103 to single-stranded DNA. | To investigate the DNA-binding site in the Escherichia coli RecA protein, RecA was covalently cross-linked to oligodeoxythymidine [p(dT)14] by irradiation with ultraviolet light. We identified the site of cross-linking of the protein when the RecA.p(dT)14 complex was formed in the absence of nucleotide cofactor as well... | ['Adenosine Triphosphate', 'Amino Acid Sequence', 'Binding Sites', 'DNA, Single-Stranded', 'DNA-Binding Proteins', 'Molecular Sequence Data', 'Photochemistry', 'Rec A Recombinases', 'Tyrosine', 'Ultraviolet Rays'] | 7,737,176 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D12.776.260'], ['L01.453.245.667'], ['H01.181.529.711'], ['D08.811.739.650', 'D08.811.913.696.445.692'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Cytogenetic analysis on children born of parents treated with immunosuppressive drugs. | Two women previously treated with cyclophosphamide had five pregnancies, resulting in seven normal offspring, including two sets of twins. All the babies had normal chromosome constitution and there was no significant chromosome damage. Apart from the twin pregnancies, which were induced, the pregnancies continued to f... | ['Azathioprine', 'Chromosomes, Human', 'Cyclophosphamide', 'Down Syndrome', 'Female', 'Humans', 'Immunosuppressive Agents', 'Infant, Newborn', 'Kidney Transplantation', 'Male', 'Prednisolone', 'Pregnancy', 'Transplantation, Autologous', 'Twins'] | 154,101 | [['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['A11.284.187.520.300', 'G05.360.162.520.300'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Statin Use and Knee Osteoarthritis Outcome Measures according to the Presence of Heberden Nodes: Results from the Osteoarthritis Initiative. | Background The exact contribution of statins to knee osteoarthritis (OA) radiographic outcomes and the characteristics of patients with OA as potential responders to statins remain unclear. Purpose To evaluate the effect of statin use on the incidence of radiographic knee OA (development of Kellgren-Lawrence grade ?2) ... | ['Aged', 'Disease Progression', 'Exostoses', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Propensity Score', 'Retrospective Studies'] | 31,502,936 | [['M01.060.116.100'], ['C23.550.291.656'], ['C05.116.540.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M01.060.116.630'], ['C05.55... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of the principle of activating blood circulation to break stasis on GMP-140 and D2 dimer in patients with acute cerebral infarction. | OBJECTIVE: To explore the clinical efficacy of the principle of activating blood circulation to break stasis (ABCBS) and its influence on platelet membranous protein particle (GMP-140) and D(2) dimer (D-dimer) before and after treatment.METHODS: Eighty-eight patients with blood stasis syndrome (BSS) of acute cerebral i... | ['Acute Disease', 'Aged', 'Aspirin', 'Blood Circulation', 'Blood Platelets', 'Cerebral Infarction', 'Female', 'Fibrin Fibrinogen Degradation Products', 'Humans', 'Male', 'Medicine, Chinese Traditional', 'Middle Aged', 'Nervous System', 'Nimodipine', 'P-Selectin', 'Phytotherapy', 'Plant Preparations', 'Platelet Aggregat... | 15,975,314 | [['C23.550.291.125'], ['M01.060.116.100'], ['D02.455.426.559.389.657.410.595.176'], ['G09.330.100'], ['A11.118.188', 'A15.145.229.188'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['D12.776.1... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Tuberculosis in children treated with second-line drugs under programmatic conditions in Lima, Peru. | OBJECTIVE: To characterise childhood tuberculosis (TB) treated with second-line drugs (SLDs) in Lima, Peru.DESIGN: Results for the age groups <5 and 5-14 years were compared and treatment outcomes were assessed in cases reported between 2011 and 2015 from six districts of Lima.RESULTS: Of 96 reported cases, 82 were eva... | ['Adolescent', 'Antitubercular Agents', 'Child', 'Child, Preschool', 'Developing Countries', 'Drug Resistance, Bacterial', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Mycobacterium tuberculosis', 'Peru', 'Retrospective Studies', 'Treatment Outcome', 'Tuberculosis, Multidrug-Resistant', 'Tuberculosis, Pulm... | 30,355,410 | [['M01.060.057'], ['D27.505.954.122.085.255'], ['M01.060.406'], ['M01.060.406.448'], ['I01.615.500.300'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['Z0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Detection and therapy of rectal cancer (author's transl)]. | The state of detection and therapy of rectal cancer in the capital of Berlin is compared with that in the rural region of Neubrandenburg. The trend and regional differences between metropolitan and rural areas were investigated. It was shown that a population-based cancer registry yields useful information. The proport... | ['Adult', 'Age Factors', 'Aged', 'Female', 'Germany, East', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Rectal Neoplasms', 'Rural Health', 'Urban Health'] | 7,315,002 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.586.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.405.469.491.307.790', 'C06.405.469.860.180.500'], ... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Relationship quality among HIV patients and their caregivers. | Despite the increasing attention to caregivers of HIV patients, no previous study has systematically investigated the effects of the relationship quality between an HIV patient and their caregiver. The present study assessed 176 dyads consisting of an HIV-infected patient and their self-identified 'caregiver'. Relation... | ['Adult', 'Antiretroviral Therapy, Highly Active', 'Caregivers', 'Cost of Illness', 'Depressive Disorder', 'HIV Infections', 'Humans', 'Interpersonal Relations', 'Male', 'Patient Compliance', 'Stress, Psychological'] | 17,364,399 | [['M01.060.116'], ['E02.319.310.075'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['F03.600.300'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acute Traumatic Brain Injury: Mortality in the Elderly. | OBJECTIVE: Despite recent progress, prognosis for the elderly (defined as aged ?70 years) afflicted by traumatic brain injury (TBI) is unfavorable and surgical intervention remains controversial. Research during the past decade on the mortality rates or prognostic factors for survival in the elderly is limited.METHODS:... | ['Acute Disease', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Anticoagulants', 'Brain Injuries', 'Craniotomy', 'Female', 'Glasgow Coma Scale', 'Head Injuries, Closed', 'Hematoma, Subdural', 'Humans', 'Male', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Sweden', 'Treatment Outcome', 'Warfarin'] | 25,731,794 | [['C23.550.291.125'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.502.119'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E04.525.190'], ['E05.318.308.940.968.875.250', 'E05.944.500', 'N04.452.859.564.800.250', 'N05.715.360.300.715.500.800.325'], [... | ['Diseases [C]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation. | The significance of positron emission tomography/computed tomography (PET/CT) in chronic lymphocytic leukemia (CLL) has not yet been systematically studied. This prospective study was aimed at assessing the benefit of PET/CT in patients with newly diagnosed or relapsed CLL and Richter transformation (RT). PET/CT examin... | ['Adult', 'Aged', 'Disease Progression', 'Female', 'Fluorodeoxyglucose F18', 'Hodgkin Disease', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymphoma, Large B-Cell, Diffuse', 'Lymphoma, Large-Cell, Anaplastic', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', '... | 23,656,196 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.656'], ['D09.254.229.500'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.080.125', 'C15.604.515.560.080.125', 'C20.683.515.528.080.125'], ['C04.557.386.480.150.585', 'C15.604.515... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Another example of enzymatic promiscuity: the polyphosphate kinase of Streptomyces lividans is endowed with phospholipase D activity. | Polyphosphate kinases (PPK) from different bacteria, including that of Streptomyces lividans, were shown to contain the typical HKD motif present in phospholipase D (PLD) and showed structural similarities to the latter. This observation prompted us to investigate the PLD activity of PPK of S. lividans, in vitro. The a... | ['Amino Acid Motifs', 'Cell Membrane', 'Choline', 'Hydrolysis', 'Phosphatidic Acids', 'Phosphatidylcholines', 'Phospholipase D', 'Phosphotransferases (Phosphate Group Acceptor)', 'Protein Conformation', 'Streptomyces lividans'] | 27,488,682 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['A11.284.149'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['G02.380'], ['D10.570.755.375.760'], ['D10.570.755.375.760.400.800'], ['D08.811.277.352.640.700.710'], ['D08.811.913.696.650'], ['G02.111.570.820.7... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Underrecognized postdosing reactions to methotrexate in patients with rheumatoid arthritis. | OBJECTIVE: To report previously underrecognized postdosing side effects of methotrexate (MTX).METHODS: Over a one and a half year period, in 2 practices, all patients with rheumatoid arthritis (RA) receiving weekly MTX, and volunteering symptoms within a few hours of MTX dosing were carefully questioned concerning the ... | ['Administration, Oral', 'Arthralgia', 'Arthritis, Rheumatoid', 'Dose-Response Relationship, Drug', 'Fatigue', 'Female', 'Humans', 'Infusions, Parenteral', 'Male', 'Methotrexate', 'Middle Aged', 'Muscular Diseases', 'Pain', 'Time Factors'] | 7,966,062 | [['E02.319.267.100'], ['C05.550.091', 'C23.888.592.612.094', 'F02.830.816.444.350', 'G11.561.790.444.350'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G07.690.773.875', 'G07.690.936.500'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510'], ['D03.633.100.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multi-model statistical process monitoring and diagnosis of a sequencing batch reactor. | Biological processes exhibit different behavior depending on the influent loads, temperature, microorganism activity, and so on. It has been shown that a combination of several models can provide a suitable approach to model such processes. In the present study, we developed a multiple statistical model approach for th... | ['Biodegradation, Environmental', 'Bioreactors', 'Models, Biological', 'Principal Component Analysis', 'Waste Disposal, Fluid', 'Water Purification'] | 17,058,291 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.115', 'J01.897.120.115'], ['E05.599.395'], ['E05.318.740.562'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Alcohol use in children: An unrecognized fact]. | Although drinking problems are now well documented in adolescents and young people, few data are available on alcohol use in children younger than 12. In France, studies have shown that 60-70% of 11-year-olds reported having tasted alcohol drinks, 4-7% having experienced drunkenness at least once, and that 5-8% might b... | ['Adolescent', 'Adolescent Behavior', 'Alcohol Drinking', 'Alcoholic Intoxication', 'Child', 'Child Behavior', 'France', 'Humans', 'Parents', 'Prevalence', 'Risk Factors'] | 27,021,882 | [['M01.060.057'], ['F01.145.022'], ['F01.145.317.269'], ['C25.775.100.175', 'F03.900.100.300'], ['M01.060.406'], ['F01.145.179'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Relationship between video head impulse test (vHIT) and caloric test in patients with vestibular neuritis. | INTRODUCTION AND OBJECTIVES: The caloric test is the gold standard for the loss of vestibular function diagnosis. The Video Head Impulse Test (vHIT) assesses the same reflex by using a video- assisted examination of the impulsive maneuver. We intend to compare the variation of results of the vHIT and the caloric test i... | ['Adolescent', 'Adult', 'Aged', 'Caloric Tests', 'Female', 'Follow-Up Studies', 'Head Impulse Test', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Reflex, Abnormal', 'Reflex, Vestibulo-Ocular', 'Regression Analysis', 'Saccades', 'Vestibular Neuronitis', 'Video Recording', 'Young Adult'] | 26,611,424 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.382.900.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.382.900.640'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Sequence homology of surface membrane proteins of Babesia rodhaini. | Four surface membrane proteins of Babesia rodhaini have previously been shown to induce a degree of protective immunity, and to carry both unique and cross-reactive determinants. cDNA clones for two of the genes coding for these proteins have been isolated and used as probes to isolate a single large genomic DNA fragme... | ['Amino Acid Sequence', 'Animals', 'Antigens, Protozoan', 'Antigens, Surface', 'Babesia', 'Base Sequence', 'DNA', 'Genes', 'Membrane Proteins', 'Molecular Sequence Data', 'Multigene Family', 'Poly A', 'RNA, Messenger', 'Sequence Homology, Nucleic Acid'] | 2,893,977 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.293'], ['D23.050.301'], ['B01.043.075.600.580.070'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['G05.360.340.024.340'], ['D12.776.543'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['D13.695.578.550.500'], ['D13.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Simultaneous editing of GABA and glutathione at 7T using semi-LASER localization. | PURPOSE: To demonstrate simultaneous editing of the two most commonly edited and overlapping signals, ã-aminobutyric acid (GABA), and glutathione (GSH), with Hadamard encoding and reconstruction of MEGA-edited spectroscopy (HERMES) using sLASER localization at 7T.METHODS: Density matrix simulations of HERMES at 7T were... | ['Adult', 'Computer Simulation', 'Female', 'Glutathione', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Phantoms, Imaging', 'Proton Magnetic Resonance Spectroscopy', 'gamma-Aminobutyric Acid'] | 29,285,783 | [['M01.060.116'], ['L01.224.160'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E07.671'], ['E05.196.867.519.775'], ['D02.241.081.114.500.350', 'D12.125.190.350']] | ['Named Groups [M]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Phase resetting in duper hamsters: specificity to photic zeitgebers and circadian phase. | The duper mutation in Syrian hamsters shortens the free-running period of locomotor activity (ôDD) to about 23 h and results in a type 0 phase-response curve (PRC) to 15-min light pulses. To determine whether exaggerated phase shifts are specific to photic cues and/or restricted to subjective night, we subjected hamste... | ['Animals', 'Biological Clocks', 'Circadian Rhythm', 'Cricetinae', 'Light', 'Mesocricetus', 'Motor Activity', 'Mutation', 'Photic Stimulation', 'Suprachiasmatic Nucleus', 'tau Proteins'] | 25,633,984 | [['B01.050'], ['G07.180.562.094'], ['G07.180.562.190'], ['B01.050.150.900.649.313.992.635.075.250'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['F01.145.632', 'G11.427.410.698'], ['G05.365.590'], ['E05.723.729'], ['A08.186.211.180.497.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MHC class II expression by microglia in tetanus toxin-induced experimental epilepsy in the rat. | Minute amounts of tetanus toxin injected into the hippocampus of rats results in an epileptiform syndrome. When the toxin injection is made unilaterally or bilaterally into the ventral hippocampus, about one-third of animals with seizures show bilateral neuronal loss in dorsal CA1 of the hippocampus after 1 week. In an... | ['Animals', 'Epilepsy', 'Gene Expression', 'Genes, MHC Class II', 'Hippocampus', 'Immunohistochemistry', 'Injections', 'Male', 'Microglia', 'Nerve Degeneration', 'Pyramidal Cells', 'Rats', 'Rats, Sprague-Dawley', 'Tetanus Toxin'] | 7,808,590 | [['B01.050'], ['C10.228.140.490'], ['G05.297'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Childhood fish oil supplementation modifies associations between traffic related air pollution and allergic sensitisation. | BACKGROUND: Studies of potential adverse effects of traffic related air pollution (TRAP) on allergic disease have had mixed findings. Nutritional studies to examine whether fish oil supplementation may protect against development of allergic disease through their anti-inflammatory actions have also had mixed findings. ... | ['Allergens', 'Asthma', 'Child', 'Child, Preschool', 'Dietary Supplements', 'Environmental Exposure', 'Female', 'Fish Oils', 'Humans', 'Infant', 'Male', 'New South Wales', 'Traffic-Related Pollution'] | 29,587,831 | [['D23.050.063'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['G07.203.300.456', 'J02.500.456'], ['N06.850.460.350'], ['D10.627.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['N06.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Intracellular survival and expression of virulence determinants of Legionella pneumophila. | Legionella pneumophila, the causative agent of Legionnaires' disease is able to live and multiply within macrophages as well as within protozoan organisms. Legionella strains inhibit phagosome-lysosome fusion and phagosome acidification. By using two different cell culture systems, one derived from human macrophages an... | ['Bacterial Toxins', 'Cloning, Molecular', 'Cosmids', 'Eukaryotic Cells', 'Gene Expression Regulation, Bacterial', 'Genomic Library', 'Hemolysin Proteins', 'Humans', 'Intracellular Membranes', 'Legionella', 'Membrane Proteins', 'Nuclear Envelope'] | 1,879,952 | [['D23.946.123'], ['E05.393.220'], ['G05.360.337.500', 'G05.360.600.250'], ['A11.450'], ['G05.308.300'], ['G05.360.325.425', 'G05.360.340.425'], ['D12.776.543.695.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.149.450', 'A11.284.835.514'], ['B03.440.400.425.450.450', 'B03.660.250.460.460'], ['D12.776... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinicopathologic behavior of gastric adenocarcinoma in Hispanic patients: analysis of a single institution's experience over 15 years. | PURPOSE: To determine the clinicopathologic behavior of gastric adenocarcinoma in Hispanics by comparing Hispanic and non-Hispanic patients treated at a single cancer center.PATIENTS AND METHODS: Medical records of patients with invasive gastric cancer treated from 1985 to 1999 were reviewed. Diagnoses were pathologica... | ['Adenocarcinoma', 'Adult', 'African Americans', 'Age of Onset', 'Aged', 'European Continental Ancestry Group', 'Female', 'Hispanic Americans', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Prognosis', 'Retrospective Studies', 'Stomach Neoplasms', 'Survival Analysis'] | 15,860,869 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['M01.686.508.400'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['E01.789'], ['E... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Whole blood harvested after granulocyte-colony stimulating factor (Neupogen) mobilization, and reinfused unprocessed after high-dose melphalan treatment, accelerates hematopoietic recovery in patients with multiple myeloma. | BACKGROUND: High-dose melphalan (HDM) is now a standard treatment for multiple myeloma (MM). Stem cell transplants are fast evolving as an alternative to bone marrow transplants because they are less traumatic and easier to perform. A study was undertaken to test if whole blood harvested after mobilizing peripheral blo... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Blood Transfusion, Autologous', 'Cytarabine', 'Dexamethasone', 'Female', 'Filgrastim', 'Granulocyte Colony-Stimulating Factor', 'Hematopoietic Stem Cells', 'Humans', 'Leukocyte Count', 'Male', 'Melphalan', 'Middle Aged', 'Multiple Myeloma', 'Pilot Pro... | 8,635,126 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.095.135.164'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D12.644.276.374.410.240.350.500', 'D12.776.395.240.200.500', 'D12.776.46... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A novel TaqMan® MGB probe for specifically detecting Streptococcus mutans]. | OBJECTIVE: To design a new TaqMan® MGB probe for improving the specificity of Streptococcus mutans's detection.METHODS: We extracted six DNA samples from different streptococcal strains for PCR reaction. Conventional nested PCR and TaqMan® MGB real-time PCR were applied independently. The first round of nested PCR was ... | ['Base Sequence', 'DNA Primers', 'DNA Probes', 'DNA, Bacterial', 'Polymerase Chain Reaction', 'RNA, Ribosomal, 16S', 'Sequence Alignment', 'Streptococcus', 'Streptococcus mutans'] | 24,136,279 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D13.444.308.212'], ['E05.393.620.500'], ['D13.444.735.686.670'], ['E05.393.751'], ['B03.353.750.737.872', 'B03.510.400.800.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Does surgical approach during total hip arthroplasty alter gait recovery during the first year following surgery? | Multiple surgical approaches exist for total hip arthroplasty (THA). Each approach has risks and benefits in regard to complications and changes in postoperative gait. This study examined the effect of three surgical approaches on postoperative gait mechanics. Thirty patients completed a self-selected speed level walki... | ['Arthroplasty, Replacement, Hip', 'Gait', 'Humans', 'Joint Diseases', 'Middle Aged', 'Range of Motion, Articular', 'Recovery of Function'] | 23,518,430 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['M01.060.116.630'], ['E01.370.600.700', 'G11.427.760'], ['G16.757']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Repositioning of charged I-II loop amino acid residues within the electric field by beta subunit as a novel working hypothesis for the control of fast P/Q calcium channel inactivation. | We have investigated the contribution of the Ca(v)beta subunits to the process of inactivation dependent of the I-II loop of Ca(v)alpha(2.1). Two amino acid residues located in the alpha1 interaction domain (AID) of the I-II loop of Ca(v)alpha(2.1) (Arg(387) and Glu(388)) have been directly implicated in voltage-depend... | ['Alanine', 'Animals', 'Arginine', 'Autoradiography', 'Calcium Channels, N-Type', 'Calcium Signaling', 'Electrophysiology', 'Glutamic Acid', 'Kinetics', 'Membrane Potentials', 'Neural Inhibition', 'Oocytes', 'Peptide Biosynthesis', 'Point Mutation', 'Protein Conformation', 'Protein Structure, Tertiary', 'Protein Subuni... | 15,078,550 | [['D12.125.042'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D12.776.157.530.400.150.585', 'D12.776.543.550.450.150.585', 'D12.776.543.585.400.150.585'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['H01.158.344... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Noninvasive determination of anaerobic threshold by monitoring the %SpO2 changes and respiratory gas exchange. | The purpose of this study was to determine the validity of noninvasive anaerobic threshold (AT) estimation using %SpO2 (arterial oxyhemoglobin saturation) changes and respiratory gas exchanges. Fifteen active, healthy males performed 2 graded exercise tests on a motor-driven treadmill in 2 separated sessions. Respirato... | ['Adult', 'Anaerobic Threshold', 'Arteries', 'Exercise', 'Heart Rate', 'Humans', 'Lactic Acid', 'Male', 'Oximetry', 'Oxygen Consumption', 'Oxyhemoglobins', 'Pulmonary Gas Exchange', 'Running', 'Young Adult'] | 19,855,338 | [['M01.060.116'], ['G03.680.110', 'G11.427.680.134'], ['A07.015.114'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.386.700.100.600', 'E05.200.124.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Conjugated linoleic acid isomers in mitochondria: evidence for an alteration of fatty acid oxidation. | The beneficial effects exerted by low amounts of conjugated linoleic acids (CLA) suggest that CLA are maximally conserved and raise the question about their mitochondrial oxidizability. Cis-9,trans-11-C(18:2) (CLA1) and trans-10,cis-12-C(18:2) (CLA2) were compared to cis-9,cis-12-C(18:2) (linoleic acid; LA) and cis-9-C... | ['Animals', 'Caprylates', 'Carnitine Acyltransferases', 'Coenzyme A Ligases', 'Fatty Acids', 'Fatty Acids, Unsaturated', 'Isomerism', 'Linoleic Acid', 'Liver', 'Male', 'Mitochondria', 'Phospholipids', 'Rats', 'Rats, Wistar'] | 12,454,273 | [['B01.050'], ['D02.241.081.222', 'D10.251.122'], ['D08.811.913.050.350'], ['D08.811.464.267.500'], ['D10.251'], ['D10.251.355'], ['G02.111.570.685', 'G02.607.445'], ['D10.251.355.310.515.500', 'D10.251.355.343.500.500'], ['A03.620'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D10.570.755'], ['B01.050.150.90... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Devitalization of Bordetella bronchiseptica in vitro using vapors of Persterile and triethyl glycol]. | Using the method of bacterial carriers, the devitalizing effect was studied of Persteril and triethylene glycol vapours, acting in vitro, on a 24-hour culture of a mixture of 39 strains of Bordetella bronchiseptica, isolated from the nasal cavity of pigs which came from five stocks suffering from the clinical form atro... | ['Acetates', 'Bordetella', 'Disinfectants', 'Glycols', 'Peracetic Acid', 'Temperature', 'Virulence', 'Volatilization'] | 111,400 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Construction and validation of a prognostic model across several studies, with an application in superficial bladder cancer. | Many models for clinical prediction (prognosis or diagnosis) are published in the medical literature every year but few such models find their way into clinical practice. The reason may be that since in most cases models have not been validated in independent data, they lack generality and/or credibility. In this paper... | ['Adult', 'Aged', 'Aged, 80 and over', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Biological', 'Predictive Value of Tests', 'Prognosis', 'Proportional Hazards Models', 'Reproducibility of Results', 'Urinary Bladder Neoplasms'] | 15,027,080 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.395'], ['E05.318.370... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CD57 as a routine neuroendocrine marker for liver metastasis. | Background: The characterization of hepatic metastases as having neuroendocrine origins is essential and the main markers currently used are chromogranin A (CgA) and synaptophysin (Syn). However, these markers may exhibit certain limitations, and the use of CD56 and CD57 can also be considered, although, due to low spe... | ['Biomarkers, Tumor', 'CD57 Antigens', 'Carcinoma, Neuroendocrine', 'Glycoprotein Hormones, alpha Subunit', 'Humans', 'Immunohistochemistry', 'Liver Neoplasms', 'Paraffin Embedding'] | 32,031,120 | [['D23.101.140'], ['D23.050.301.264.894.157', 'D23.101.100.894.157'], ['C04.557.465.625.650.240', 'C04.557.470.200.025.370', 'C04.557.580.625.650.240'], ['D06.472.699.322.326.562', 'D06.472.699.322.576.288.750', 'D06.472.699.322.576.463.249', 'D06.472.699.631.525.343.288.750', 'D06.472.699.631.525.343.463.249', 'D06.47... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical evaluation and grading practices in schools of nursing: national survey findings part II. | To better understand how nurse educators evaluate and grade students' clinical practice, the Evaluation of Learning Advisory Council of the National League for Nursing conducted a survey of faculty (N = 1,573) in all types of prelicensure RN programs. This article describes the findings of that survey in relation to cl... | ['Attitude of Health Personnel', 'Clinical Competence', 'Education, Nursing, Associate', 'Education, Nursing, Baccalaureate', 'Education, Nursing, Diploma Programs', 'Education, Nursing, Graduate', 'Educational Measurement', 'Faculty, Nursing', 'Humans', 'Nursing Education Research', 'Nursing Records', 'Patient Simulat... | 19,999,935 | [['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.462.233'], ['I02.358.462.316'], ['I02.358.462.482'], ['I02.358.337.450', 'I02.358.462.565'], ['I02.399'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.64... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Risk management in clinical practice. Part 8. Temporomandibular disorders. | Temporomandibular disorders can arise apparently idiopathically, as a result of macro-trauma or micro-trauma such as parafunction, as a result of a separate disease process or as a consequence of dental treatment. The objectives of this chapter are to make the practitioner aware of his/her responsibilities in any of th... | ['Dental Occlusion', 'Dental Records', 'Dental Restoration, Permanent', 'Diagnostic Imaging', 'Equipment Design', 'Facial Pain', 'Headache', 'Humans', 'Jaw Relation Record', 'Joint Dislocations', 'Masticatory Muscles', 'Medical History Taking', 'Neuromuscular Agents', 'Occlusal Adjustment', 'Occlusal Splints', 'Orthodo... | 21,072,093 | [['E06.276', 'G10.549.208'], ['E05.318.308.940.375', 'L01.399.250.900.375', 'N04.452.859.341', 'N05.715.360.300.715.330', 'N06.850.520.308.940.375'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['E01.370.350'], ['E05.320'], ['C23.888.592.612.330'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells. | This report is designed to explore the exact molecular mechanism by which artesunate (ART), a semisynthetic derivative of the herbal antimalaria drug artemisinin, induces apoptosis in human lung adenocarcinoma (ASTC-a-1 and A549) cell lines. ART treatment induced ROS-mediated apoptosis in a concentration- and time-depe... | ['Adenocarcinoma', 'Antineoplastic Agents', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Artemisinins', 'Artesunate', 'Bcl-2-Like Protein 11', 'Cell Line, Tumor', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'Membrane Proteins', 'Proto-Oncogene Proteins', 'Reactive Oxygen Species', 'Voltage-D... | 22,378,505 | [['C04.557.470.200.025'], ['D27.505.954.248'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['D01.248.497.158.685.750.212', 'D01.339.431.374.212', 'D01.650.550.750.200', 'D02.389.338.055', 'D02.455.849.765.211'], ['D01.248.497.158.685.750.212.500', 'D01.339.431.374.212.500', 'D01.650.550.750.200.500', '... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Video-assisted thoracoscopic ligation of patent ductus arteriosus: safe and outpatient. | BACKGROUND: Minimally invasive techniques for interruption of patent ductus arteriosus have been reported, but are in use at only a few centers. We examined our series of patients who underwent thoracoscopic patent ductus arteriosus ligation.METHODS: We reviewed 59 consecutive patients, age 6 days to 50 years, weighing... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Ductus Arteriosus, Patent', 'Endoscopy', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Ligation', 'Male', 'Middle Aged', 'Retrospective Studies', 'Thoracoscopy', 'Treatment Outcome', 'Video Recording'] | 9,768,942 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C14.240.400.340', 'C14.280.400.340', 'C16.131.240.400.340'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E04.426'], ['M01.060.116.630'], ['E05.318.372.500.500.500',... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
PET imaging in patients with coal workers pneumoconiosis and suspected malignancy. | Positron Emission Tomography (PET) with F-18-fluorodeoxyglucose is commonly used in the evaluation of lung nodules; however, there is limited data on the PET appearance of coal worker's pneumoconiosis (CWP) and its utility for diagnosing lung malignancy in this setting. Six cases of CWP and suspected malignancy are rep... | ['Aged', 'Anthracosis', 'Diagnostic Imaging', 'Fluorodeoxyglucose F18', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Positron-Emission Tomography', 'Predictive Value of Tests', 'Radiopharmaceuticals', 'Survival Rate', 'Tomography, X-Ray Computed'] | 19,395,909 | [['M01.060.116.100'], ['C08.381.483.581.062', 'C08.381.520.702.062'], ['E01.370.350'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E01.789.625'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.35... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenovirus-mediated tBid overexpression results in therapeutic effects on p53-resistant hepatocellular carcinoma. | Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide with a very high mortality. Because the success of the conventional therapies is limited, gene therapy may represent an alternative for HCC management. Our earlier study has shown that Bid plays a role in the development of HCC. The aim of ... | ['Adenoviridae', 'Animals', 'Apoptosis', 'BH3 Interacting Domain Death Agonist Protein', 'Carcinoma, Hepatocellular', 'Caspases', 'Cell Line', 'DNA, Recombinant', 'DNA-Binding Proteins', 'Enzyme Activation', 'Gene Expression', 'Genetic Therapy', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Promoter Regions, Genetic', ... | 16,708,390 | [['B04.280.030'], ['B01.050'], ['G04.146.954.035'], ['D12.644.360.075.718.968', 'D12.776.476.075.718.937'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.251.21... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Altered nucleotide receptor expression in a murine model of cerebral malaria. | In cerebral malaria, the most severe complication of malaria, both neurotransmission mechanisms and energy metabolism are affected. To understand how metabolic changes modify neurotransmission, we examined P2 receptor expression in a murine model of cerebral malaria. Quantitative polymerase chain reaction experiments r... | ['Animals', 'Brain', 'Gene Expression Regulation', 'Immunohistochemistry', 'Malaria, Cerebral', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Plasmodium berghei', 'Protein Array Analysis', 'RNA, Messenger', 'Receptors, Purinergic P2'] | 19,758,097 | [['B01.050'], ['A08.186.211'], ['G05.308'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['C01.207.205.300.500', 'C01.610.105.300... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Concerns of entering dental students. | First-year students from three dental schools were surveyed during their first week of classes to assess their areas of concern. Factor analysis of the data revealed five independent areas of concern--psychosocial, academic, time, isolation, and money. A high degree of similarity was found in the order in which student... | ['Education, Dental', 'Humans', 'Interpersonal Relations', 'Psychological Distance', 'Social Adjustment', 'Students, Dental', 'Time Factors'] | 6,937,528 | [['I02.358.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.145.813.630', 'F01.829.316.777'], ['F01.145.813.621'], ['M01.848.769.519'], ['G01.910.857']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Heterophoria as a measure of subjects' alertness during recovery from general anesthesia. | The purpose of the study was to measure the influence of subjects' alertness on heterophoria. An experimental group of 43 patients was measured with the Maddox Wing test for heterophoria. Exophoria was greater 1 1/2, 2 1/2, and 3 1/2 hr. after the end of general anesthesia than at baseline level. Data for a control gro... | ['Adult', 'Anesthesia Recovery Period', 'Anesthesia, General', 'Arousal', 'Convergence, Ocular', 'Enflurane', 'Eye Movements', 'Female', 'Halothane', 'Humans', 'Isoflurane', 'Male', 'Middle Aged'] | 2,608,417 | [['M01.060.116'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['E03.155.197'], ['F02.830.104', 'G11.561.035'], ['G14.350.217'], ['D02.355.601.400'], ['G11.427.410.140', 'G14.350'], ['D02.455.526.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.355.601.570'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Successful treatment of Rituximab-resistant Epstein-Barr virus-associated post-transplant lymphoproliferative disorder using R-CHOP. | Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disorder (EBV-PTLD) is a complication of hematopoietic stem cell transplantation (HSCT). Standard initial treatment of patients with EBV-PTLD includes administration of rituximab or dose reduction of a calcineurin inhibitor. We report successful ch... | ['Adult', 'Anemia, Aplastic', 'Antibodies, Monoclonal, Murine-Derived', 'Antineoplastic Combined Chemotherapy Protocols', 'Cyclophosphamide', 'Doxorubicin', 'Epstein-Barr Virus Infections', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Herpesvirus 4, Human', 'Humans', 'Lymphoproliferative Disorders', 'Prednison... | 25,318,948 | [['M01.060.116'], ['C15.378.071.085', 'C15.378.190.223.250'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D02.455.426.559.847.562.050.200.17... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Differences in Microsatellite Instability Profiles between Endometrioid and Colorectal Cancers: A Potential Cause for False-Negative Results? | Colorectal (CRCs) and endometrioid (EMCs) cancers in patients with Lynch syndrome exhibit microsatellite instability (MSI) detected by PCR or immunohistochemistry (IHC). While both assays are equally sensitive for CRCs, some suggest that PCR has a higher false-negative rate than IHC in EMCs. We assessed the MSI profile... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma, Endometrioid', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'Endometrial Neoplasms', 'False Negative Reactions', 'Female', 'Humans', 'Male', 'Microsatellite Instability', 'Microsatellite Repeats', 'Middle Aged', 'MutS DNA Mismatch-Binding Prote... | 27,810,331 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['C04.588.274.476.411.307.190', 'C04.700.250', 'C06.301.371.411.307... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relevance of prognostic factors in the decision-making of stem cell transplantation in Myelodysplastic Syndromes. | The hematopoietic stem cell transplantation (HSCT) is the only curative alternative for Myelodysplastic Syndrome (MDS), but many patients are not eligible for this treatment, as there are several limiting factors, especially in the case of patients with low-risk MDS. The aim of this study is to discuss the factors that... | ['Aged', 'Decision Making', 'Fatal Outcome', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Male', 'Middle Aged', 'Myelodysplastic Syndromes', 'Prognosis', 'Risk Assessment'] | 27,982,317 | [['M01.060.116.100'], ['F02.463.785.373'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C15.378.190.625'], ['E01.789'], ['E05.3... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reduction in complement activation from biomaterials by removal of air nuclei from the surface roughness. | The activation of the rabbit complement system by each of three different synthetic materials is reported. Samples of each type of material were subjected to one of two different priming procedures. One priming procedure was intended to remove the air nuclei from the surface roughness of the materials; the other proced... | ['Air', 'Animals', 'Biocompatible Materials', 'Cell Adhesion', 'Cellophane', 'Complement Activation', 'Complement C5', 'Complement C5a', 'In Vitro Techniques', 'Polytetrafluoroethylene', 'Rabbits', 'Silicone Elastomers', 'Surface Tension'] | 6,715,393 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G04.022'], ['D25.720.099.500.252', 'J01.637.051.720.099.500.252', 'J01.637.118'], ['G12.274'], ['D12.776.124.486.274.450'], ['D12.776.124.486.274.024.270', 'D12.776.124.486.274.450.250'], ['E05.481'], ['D0... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Consequences of chronic phenobarbital blockade of spontaneous motility in chick embryos for the development of central motor output activity. | The consequences of the chronic continuous administration of Na+-phenobarbital in an average dose of 9.8 mg/kg e.w./24 h were studied in chick embryos. Administration was always started on the 4th day of incubation and lasted 4-12 days. Spontaneous motility was tested in 13- and 17-day-old embryos. The continuous, chro... | ['Animals', 'Bicuculline', 'Central Nervous System', 'Chick Embryo', 'Motor Activity', 'Oxazepam', 'Pentylenetetrazole', 'Phenobarbital', 'Strychnine', 'gamma-Aminobutyric Acid'] | 2,975,010 | [['B01.050'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['A08.186'], ['A13.350.150', 'A16.331.200'], ['F01.145.632', 'G11.427.410.698'], ['D03.633.100.079.080.070.663'], ['D03.383.066.600'], ['D03.383.742.698.253.650'], ['D03.132.436.681.722', 'D03.633.100.473.402.681.722', 'D03.633.100.496.500.500.681.722'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coagulopathy after a liver resection: is it over diagnosed and over treated? | BACKGROUND: Prothrombin time-international normalized ratio (PT-INR) is widely utilized to guide plasma therapy and initiation of thromboprophylaxis after a hepatectomy. Thrombelastography (TEG) monitors shear elasticity, which is sensitive to cellular and plasma components in blood, allowing for functional assessment ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Coagulation Disorders', 'Female', 'Follow-Up Studies', 'Hepatectomy', 'Humans', 'Liver Diseases', 'Male', 'Middle Aged', 'Prognosis', 'Prospective Studies', 'Prothrombin Time', 'Thrombelastography', 'Thrombolytic Therapy', 'Thrombosis'] | 23,458,574 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C15.378.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.750.625', 'N05.71... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sex differences in host defence interfere with parasite-mediated selection for outcrossing during host-parasite coevolution. | The Red Queen hypothesis proposes that coevolving parasites select for outcrossing in the host. Outcrossing relies on males, which often show lower immune investment due to, for example, sexual selection. Here, we demonstrate that such sex differences in immunity interfere with parasite-mediated selection for outcrossi... | ['Adaptation, Physiological', 'Animals', 'Bacillus thuringiensis', 'Biological Evolution', 'Caenorhabditis elegans', 'Female', 'Hermaphroditic Organisms', 'Host-Parasite Interactions', 'Host-Pathogen Interactions', 'Male', 'Selection, Genetic', 'Self-Fertilization', 'Sex Characteristics'] | 23,301,667 | [['G07.025', 'G16.012.500'], ['B01.050'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['G05.045', 'G16.075'], ['B01.050.500.500.294.400.875.660.250.250'], ['B05.275'], ['G16.527.200.400'], ['G06.462', 'G16.527.200']... | ['Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Commercial plant extracts may act as antioxidants or pro-oxidants in cosmetic emulsions based on argan oil. | Cosmetic emulsions containing plant extracts should be tested in a range of temperatures from 5°C to 40°C to be sure that they will be stable during general use by consumers and that plant extracts used as antioxidants do not accelerate oxidative degradation of their oil base. The oxidative stability of argan oil-in-wa... | ['Antioxidants', 'Cosmetics', 'Emulsions', 'Malpighiaceae', 'Oxidants', 'Plant Extracts', 'Plant Oils', 'Rosa', 'Salix', 'Water'] | 29,619,939 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D27.720.269', 'J01.516.213'], ['D20.280.260', 'D26.255.165.260'], ['B01.650.940.800.575.912.250.859.797.690'], ['D27.720.642', 'D27.888.569.540'], ['D20.215.784.500', 'D26.667'], ['D10.627.700', 'D20.215.784.750'], ['B01.650.940.800.575.912.250.859.937.5... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Is transcutaneous oxygen tension independent of variations in blood flow and in arterial blood pressure? | Whether transcutaneous oxygen tension (TcPO2) is independent of minor variations in perfusion under the TcPO2 electrode, as is claimed, was studied in 18 feet of 16 young healthy adults. The TcPO2 electrode was mounted on the dorsum of the foot and operated at 43 degrees C, while the blood pressure was changed by eleva... | ['Adult', 'Blood Gas Analysis', 'Blood Pressure', 'Electrodes', 'Female', 'Foot', 'Humans', 'Male', 'Oxygen', 'Regional Blood Flow', 'Respiration', 'Skin'] | 7,159,703 | [['M01.060.116'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E07.305.250'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.185.550', 'D01.362.670'], ['G09.330.100.780'], ['G09.772.705'], ['A17.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A fatal case of levamisole induced bone marrow failure. | A 20-year-old college student presented with high grade, intermittent fever for 10 days associated with blood stained loose stools after taking tablet levamisole for 17 days for vitiligo vulgaris. He was febrile, had a toxic appearance and appeared pale. Investigations showed neutropaenia with thrombocytopaenia. Blood ... | ['Adjuvants, Immunologic', 'Bone Marrow Failure Disorders', 'Diarrhea', 'Fatal Outcome', 'Fever', 'Granulocyte Colony-Stimulating Factor', 'Humans', 'Levamisole', 'Male', 'Neutropenia', 'Platelet Transfusion', 'Shock, Septic', 'Vitiligo', 'Young Adult'] | 31,570,359 | [['D27.505.696.477.067'], ['C15.378.190.223'], ['C23.888.821.214'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C23.888.119.344'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200', 'D12.776.467.374.410.240.350', 'D23.529.374.410.240.350'], ['B... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of pulse oximetry screening in Middle Tennessee: cases for consideration before universal screening. | OBJECTIVE: Pulse oximetry screening of asymptomatic newborns is suggested as a life-saving procedure for the timely detection of critical congenital heart disease (CHD) in asymptomatic newborns. We evaluated this screening and report cases that demonstrate problems with screening in a non-research setting.STUDY DESIGN:... | ['Asymptomatic Diseases', 'Community Health Nursing', 'Critical Illness', 'Early Diagnosis', 'Heart Defects, Congenital', 'Humans', 'Infant, Newborn', 'Needs Assessment', 'Neonatal Nursing', 'Neonatal Screening', 'Oximetry', 'Physical Examination', 'Program Evaluation', 'Research Report', 'Tennessee'] | 20,508,595 | [['C23.550.291.187'], ['H02.478.676.150', 'N02.421.143.150'], ['C23.550.291.625'], ['E01.390'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['H02.478.676.390.600', 'H02.478.676.631.600', 'N02.421.... | ['Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Use of pericardial strip for reinforcement of proximal anastomosis in Bentall's procedure. | Bleeding from a proximal suture line is not uncommon following composite graft anastomosis in Bentall's procedure. Passage of valve sutures through the pericardial strip, which is used to encircle the sewing ring of the composite graft, strengthens the repair. The strip can also be sutured to the left ventricular outfl... | ['Anastomosis, Surgical', 'Aorta', 'Aortic Valve', 'Blood Loss, Surgical', 'Blood Vessel Prosthesis Implantation', 'Heart Valve Prosthesis Implantation', 'Hemostasis, Surgical', 'Humans', 'Pericardium', 'Suture Techniques', 'Treatment Outcome'] | 20,685,809 | [['E04.035'], ['A07.015.114.056'], ['A07.541.510.110'], ['C23.550.414.300', 'C23.550.505.300'], ['E04.100.814.868.500', 'E04.650.200'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['E02.520.490', 'E04.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.795', 'A10.615.789.470'], ['E04.987.775'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ventricular arrhythmias and risk of death and acute myocardial infarction in apparently healthy subjects of age >or=55 years. | Increased ventricular ectopic activity and even more complex arrhythmias are not uncommon in subjects without apparent heart disease. However, their prognostic significance has been controversial and not updated in recent years. The prevalence and prognostic significance of different ventricular arrhythmias were studie... | ['Aged', 'Denmark', 'Electrocardiography, Ambulatory', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Predictive Value of Tests', 'Prognosis', 'Proportional Hazards Models', 'Risk Assessment', 'Risk Factors', 'Ventricular Premature Complexes'] | 16,635,610 | [['M01.060.116.100'], ['Z01.542.816.124'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Carotenogenesis of five strains of the algae Dunaliella sp. (Chlorophyceae) isolated from Venezuelan hypersaline lagoons]. | We evaluated discontinuous cultures (Algal medium at 0.5 mM of NaNO3, and 27% NaCI) of five strains of Dunaliella sp. isolated from Venezuelan hypersaline lagoons (Araya, Coche, Peonia, Cumaraguas. and Boca Chica) and one strain from a reference collection (Dunaliella salina, LB1644). Cultures were maintained to 25+/-1... | ['Carotenoids', 'Chlorophyll', 'Chlorophyll A', 'Chlorophyta', 'Light', 'Seawater', 'Venezuela'] | 17,354,444 | [['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D03.383.129.578.840.374.140', 'D03.633.400.909.374.140', 'D04.345.783.374.140'], ['B01.650.940.150'], ['G01.358.500.505.650', 'G01.590.540', 'G01.75... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Extensive gastrointestinal metabolic conversion limits the oral bioavailability of the dopamine D2 agonist N-0923 in freely moving rats. | The absorption of the dopamine D2 agonist S(-)-2-(N-propyl-N-2-thienylethylamino)-5-hydroxy-tetralin hydrochloride (1; N-0923) was studied in fasted and non-fasted male Albino Wistar rats after intragastric administration of 10.0 mumol.kg-1. Blood samples up to 120 min were obtained from the portal vein and the levels ... | ['Animals', 'Biological Availability', 'Chromatography, High Pressure Liquid', 'Digestive System', 'Dopamine Agents', 'Gastric Juice', 'Gastrointestinal Contents', 'Male', 'Rats', 'Rats, Wistar', 'Receptors, Dopamine D2', 'Tetrahydronaphthalenes', 'Thiophenes'] | 1,359,583 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['E05.196.181.400.300'], ['A03'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['A12.200.307'], ['A12.519'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D12.776.543.750.670.300.400.500', 'D12.776.543.750.695.150.400... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Indoleamine 2,3 dioxygenase and human leucocyte antigen-G inhibit the T-cell alloproliferative response through two independent pathways. | Both human leucocyte antigen (HLA)-G and indoleamine 2,3 dioxygenase (IDO) are key molecules involved in immune tolerance. HLA-G is a non-classical HLA class I molecule that can be expressed in both membrane-bound (HLA-G1) and soluble (HLA-G5) forms, both of which exhibit tolerogenic properties via interaction with inh... | ['Cell Proliferation', 'Cells, Cultured', 'Enzyme-Linked Immunosorbent Assay', 'HLA Antigens', 'HLA-G Antigens', 'Histocompatibility Antigens Class I', 'Humans', 'Immune Tolerance', 'Indoleamine-Pyrrole 2,3,-Dioxygenase', 'Kynurenine', 'Lymphocyte Activation', 'Lymphocyte Culture Test, Mixed', 'Signal Transduction', 'T... | 16,236,119 | [['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.489.700', 'D12.776.543.550.439.700', 'D23.050.301.500.100.700', 'D23.050.301.500.45... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A trial for comparing methods for eliciting treatment preferences from men with advanced prostate cancer: results from the initial visit. | OBJECTIVE: The objective of this study was to evaluate the convergent validity of 3 types of utility measures: standard gamble, time tradeoff, and rating scale.RESEARCH DESIGN: A prospective cohort of 120 men with advanced prostate cancer were first asked to rank order 8 health states, and then utility values were obta... | ['Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Attitude to Health', 'Cost-Benefit Analysis', 'Decision Making', 'Humans', 'Male', 'Middle Aged', 'Patient Participation', 'Prostatic Neoplasms', 'Psychometrics', 'Reproducibility of Results', 'United States'] | 11,021,677 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.100.150', 'N05.300.150'], ['N03.219.151.125'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.42... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Impact of visual features on the segmentation of gastroenterology images using normalized cuts. | Gastroenterology imaging is an essential tool to detect gastrointestinal cancer in patients. Computer-assisted diagnosis is desirable to help us improve the reliability of this detection. However, traditional computer vision methodologies, mainly segmentation, do not translate well to the specific visual characteristic... | ['Algorithms', 'Barrett Esophagus', 'Cluster Analysis', 'Databases, Factual', 'Endoscopy, Digestive System', 'Gastrointestinal Tract', 'Humans', 'Image Processing, Computer-Assisted', 'Narrow Band Imaging', 'Stomach Neoplasms'] | 23,204,269 | [['G17.035', 'L01.224.050'], ['C04.834.154', 'C06.405.117.102'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E01.370.372.250', 'E01.370.388.250.250', 'E04.210.240', 'E04.502.250.250'], ['A03.556'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Glucose consumption and dehydrogenase activity of the cells of the arsenite-oxidizing bacterium Pseudomonas putida]. | The rates of glucose assimilation and dehydrogenase activity were studied in Pseudomonas putida oxidizing arsenite. The rate of glucose utilization by the cells decreased in the presence of arsenites in the medium at the beginning because of the microbial adaptation to arsenite. The activity of dehydrogenase fell down ... | ['Arsenic', 'Arsenites', 'Culture Media', 'Glucose', 'Oxidation-Reduction', 'Oxidoreductases', 'Pseudomonas'] | 4,058,329 | [['D01.268.513.249'], ['D01.075.050', 'D01.248.497.158.055'], ['D27.720.470.305', 'E07.206'], ['D09.947.875.359.448'], ['G02.700', 'G03.295.531'], ['D08.811.682'], ['B03.440.400.425.625.625', 'B03.660.250.580.590']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions. | Plasmid DNA was gamma-irradiated or treated with H2O2 in the presence of Cu2+ to generate oxygen free radical-induced lesions. Open circular DNA molecules were removed by ethidium bromide/CsCl density gradient centrifugation. The closed circular DNA fraction was treated with the Escherichia coli reagent enzymes endonuc... | ['Cell Line', 'DNA Damage', 'DNA Repair', 'DNA, Single-Stranded', 'Free Radicals', 'Genetic Complementation Test', 'Humans', 'Oxygen', 'Xeroderma Pigmentosum'] | 8,327,515 | [['A11.251.210'], ['G05.200'], ['G02.111.222', 'G05.219'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D01.339', 'D02.389'], ['E05.393.281.526'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.185.550', 'D01.362.670'], ['C04.834.867', 'C16.131.831.936', 'C16.320.850.970', 'C17.800.6... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical, morphometric and ultrastructural aspects in a new model of spinal cord compression. | A new model of spinal cord compression is presented. Forty-two New Zealand albino rabbits weighing between 1.2 and 1.5 kg were submitted to spinal cord compression to about half of its normal diameter by vascular Sugita's clip to different compression time (sham, 5-10-20 minutes e 1-6-12 hours) and sacrified after 72 h... | ['Animals', 'Disease Models, Animal', 'Myelin Sheath', 'Nerve Fibers, Myelinated', 'Rabbits', 'Spinal Cord', 'Spinal Cord Compression'] | 1,774,592 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.800.690.500', 'A10.755.503', 'A11.284.149.165.600', 'A11.650.600.500', 'A11.650.800.500', 'A11.671.501.512.560', 'A11.671.514.553'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.514'], ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bioorthogonal turn-on probes for imaging small molecules inside living cells. | Glowing tags: a series of activatable ("turn-on") tetrazine-conjugated fluorescent probes was developed, which react rapidly in an inverse-electron-demand [4+2] cycloaddition with strained dienophiles such as trans-cyclooctene, thereby strongly increasing the fluorescence intensity. The novel turn-on probes were applie... | ['Animals', 'Fluorescent Dyes', 'Microscopy, Confocal', 'Molecular Imaging', 'Photochemical Processes'] | 20,306,505 | [['B01.050'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E01.370.350.515.395', 'E05.595.395'], ['E01.370.350.557', 'E05.601.555'], ['G02.740']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Malignant potential of oral submucous fibrosis due to intraoral trauma. | It is not very clear why oral submucous fibrosis (OSF) is prone to develop squamous cell carcinoma (SCC). Experimental studies on hamster have shown that wounding of oral mucosa promotes induction of epithelial dysplasia (ED) initiated with carcinogens. Hence, a study was undertaken to find the effect of intraoral trau... | ['Biopsy, Needle', 'Carcinoma, Squamous Cell', 'Cell Transformation, Neoplastic', 'Female', 'Fibrosis', 'Humans', 'India', 'Male', 'Mouth', 'Mouth Mucosa', 'Mouth Neoplasms', 'Prognosis', 'Risk Assessment'] | 11,216,327 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C23.550.355'], ['B01.050.150.900.649.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Anti-emetic drug effects on cognitive and psychomotor performance: granisetron vs. ondansetron. | The central objectives of this study were to evaluate the cognitive, psychomotor and subjective effects of two anti-emetic drugs of established value in the prophylaxis of radiation induced nausea and vomiting. The drugs of interest were granisetron (Kytril, SmithKline Beecham Pharmaceuticals, Philadelphia, PA; 1 mg ta... | ['Adolescent', 'Adult', 'Affect', 'Antiemetics', 'Cognition', 'Cross-Over Studies', 'Double-Blind Method', 'Drug Monitoring', 'Female', 'Granisetron', 'Humans', 'Male', 'Nausea', 'Ondansetron', 'Psychomotor Performance', 'Radiotherapy', 'Vomiting'] | 9,184,738 | [['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['F02.463.188'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.520.200'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Elastosonography scoring and strain index of thyroid nodules with Hurthle cells. | BACKGROUND: This study evaluated the effectiveness of elastosonography (ES) scoring and strain index (SI) in diagnosing patients with thyroid nodules composed primarily of Hurthle cells.METHODS: This study retrospectively analyzed 57 patients with thyroid nodules composed predominantly of Hurthle cells on fine needle a... | ['Adult', 'Aged', 'Biopsy, Fine-Needle', 'Elasticity Imaging Techniques', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oxyphil Cells', 'Retrospective Studies', 'Thyroid Nodule', 'Ultrasonography', 'Young Adult'] | 25,310,014 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.370.350.850.270'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Steady-state function of the ubiquitous mammalian Na/H exchanger (NHE1) in relation to dimer coupling models with 2Na/2H stoichiometry. | We describe the steady-state function of the ubiquitous mammalian Na/H exchanger (NHE)1 isoform in voltage-clamped Chinese hamster ovary cells, as well as other cells, using oscillating pH-sensitive microelectrodes to quantify proton fluxes via extracellular pH gradients. Giant excised patches could not be used as giga... | ['Allosteric Regulation', 'Animals', 'CHO Cells', 'Cell Line, Transformed', 'Cricetinae', 'Cricetulus', 'Cytoplasm', 'Dimerization', 'Extracellular Space', 'Female', 'Fibroblasts', 'Hydrogen-Ion Concentration', 'Ion Channel Gating', 'Ion Transport', 'Kinetics', 'Mammals', 'Mice', 'Models, Molecular', 'Opossums', 'Patch... | 18,824,592 | [['G02.111.044'], ['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['A11.251.210.172'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['A11.284.430.214'], ['G02.206', 'G03.230'], ['A10.082.500', 'A11.284.295'], ['A11.329.228'], ['G02.300'], ['G02.111.820.400', 'G04.835.40... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of changes in the nuclear phase and evaluation of male germ units by flow cytometry during in vitro pollen tube growth in Alstroemeria aurea. | This study aimed to analyze male gamete behavior from mature pollen to pollen tube growth in the bicellular pollen species Alstroemeria aurea. For mature pollen, pollen protoplasts were examined using flow cytometry. The protoplasts showed two peaks of DNA content at 1C and 1.90C. Flow cytometry at different developmen... | ['Alstroemeria', 'Cell Differentiation', 'Cell Nucleus', 'DNA, Plant', 'Flow Cytometry', 'Genes, Plant', 'Pollen', 'Pollen Tube'] | 19,151,916 | [['B01.650.940.800.575.912.250.618.875.088'], ['G04.152'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D13.444.308.435'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['G05.360.340.024... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Angiopoietin 2 induces astrocyte apoptosis via ávâ5-integrin signaling in diabetic retinopathy. | The vascular leakage in diabetic retinopathy leads to macular edema and vision loss. Although astrocyte play an important role in regulating blood-brain barrier integrity in the brain, the precise role of astrocyte in blood-retinal barrier was yet to be elucidated. This study aimed to investigate the role of angiopoiet... | ['Angiopoietin-2', 'Animals', 'Apoptosis', 'Astrocytes', 'Diabetic Retinopathy', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Receptors, Vitronectin', 'Recombinant Proteins', 'Signal Transduction'] | 26,890,140 | [['D12.644.276.100.100.200', 'D12.776.467.100.100.200', 'D23.529.100.100.200'], ['B01.050'], ['G04.146.954.035'], ['A08.637.200', 'A11.650.200'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of quality of kefir from milk obtained from goats supplemented with a diet rich in bioactive compounds. | BACKGROUND: The composition of bioactive components in dairy products depends on their content in raw milk and the processing conditions. The experimental material consisted of the milk of dairy goats supplemented with 120 g d(-1) per head of false flax cake. The aim of the study was to evaluate the quality of kefir pr... | ['Animals', 'Brassicaceae', 'Cultured Milk Products', 'Diet', 'Dietary Supplements', 'Fatty Acids, Omega-3', 'Fatty Acids, Unsaturated', 'Goats', 'Humans', 'Linoleic Acids, Conjugated', 'Trans Fatty Acids'] | 25,042,847 | [['B01.050'], ['B01.650.940.800.575.912.250.157'], ['G07.203.200.500', 'G07.203.300.350.300', 'J02.350.500', 'J02.500.350.300'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450'], ['D10.251.355'], ['B01.050.150.900.649.313.500.380.513'], ['B01.050.150... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The association of dehydroepiandrosterone and dehydroepiandrosterone sulfate with anxiety sensitivity and electronic diary negative affect among smokers with and without posttraumatic stress disorder. | Posttraumatic stress disorder (PTSD) is associated with increased smoking initiation, maintenance, and relapse. Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are neurosteroids that have been associated with mood measures as well as smoking status, and nicotine is associated with increased DHEA and DHEAS levels... | ['Adult', 'Affect', 'Anxiety', 'Biomarkers', 'Dehydroepiandrosterone', 'Dehydroepiandrosterone Sulfate', 'Female', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Self Report', 'Smoking', 'Stress Disorders, Post-Traumatic'] | 23,771,199 | [['M01.060.116'], ['F01.470.047'], ['F01.470.132'], ['D23.101'], ['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.952'], ['D04.210.500.054.079.429.625.300', 'D04.210.500.578.502.400.300', 'D06.472.040.502.400.300', 'D06.472.334.851.968.952.300'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence and risk factors of peripheral vascular disease in a selected South Indian population: the Chennai Urban Population Study. | OBJECTIVE: The epidemiology of peripheral vascular disease has rarely been studied in non-European populations. The purpose of this study was to determine the prevalence and risk factors of peripheral vascular disease (PVD) among South Indians.RESEARCH DESIGN AND METHODS: The Chennai Urban Population Study is an epidem... | ['Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Female', 'Glucose Intolerance', 'Glucose Tolerance Test', 'Humans', 'India', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Odds Ratio', 'Peripheral Vascular Diseases', 'Predictive Value of Tests', 'Prevalence', 'Regression Analysis', 'Risk Fact... | 10,977,021 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['C18.452.394.952.500'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['E05.318.740.150.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Estimation of Sparse VAR Models with Artificial Neural Networks for the Analysis of Biosignals. | Vector autoregressive models (VAR models) are often used to model and to analyze multivariate time series, especially to provide short-term forecasts. A common method of estimating coefficients of these VAR models is solving the Yule- Walker equations. This work introduces and investigates a method to set up "sparse" V... | ['Algorithms', 'Biosensing Techniques', 'Computer Simulation', 'Neural Networks, Computer'] | 31,946,894 | [['G17.035', 'L01.224.050'], ['E05.601.043'], ['L01.224.160'], ['G17.485', 'L01.224.050.375.605']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Trust Model for Protection of Personal Health Data in a Global Environment. | Successful health care, eHealth, digital health, and personal health systems increasingly take place in cross-jurisdictional, dynamic and risk-encumbered information space. They require rich amount of personal health information (PHI). Trust is and will be the cornerstone and prerequisite for successful health services... | ['Computer Security', 'Computer Systems', 'Confidentiality', 'Health Records, Personal', 'Humans', 'Privacy', 'Telemedicine', 'Trust'] | 29,295,082 | [['L01.224.134', 'N04.452.910.200'], ['L01.224.230'], ['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['E05.318.308.940.968.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.352.500', 'N03.706.437.352.500', 'N03.706.615.862'], ... | ['Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis. | PURPOSE: The induction of apoptotic pathways in cancer cells offers a novel and potentially useful approach to improve patient responses to conventional chemotherapy. Tissue factor pathway inhibitor-2 (TFPI-2) is a protease inhibitor that is abundant in the extracellular matrix and highly expressed in noninvasive cells... | ['Adenoviridae', 'Apoptosis', 'Blotting, Western', 'Brain Neoplasms', 'Caspases', 'Cell Line, Tumor', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Gene Expression', 'Genetic Therapy', 'Genetic Vectors', 'Glioblastoma', 'Glycoproteins', 'Humans', 'In Situ Nick-End Labeling', 'Reverse Transcriptase Polymerase Cha... | 17,575,213 | [['B04.280.030'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.2... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of a standardized morbidity surveillance form for use during disasters caused by natural hazards. | INTRODUCTION: Surveillance for health outcomes is critical for rapid responses and timely prevention of disaster-related illnesses and injuries after a disaster-causing event. The Disaster Surveillance Workgroup (DSWG) of the US Centers for Disease Control and Prevention developed a standardized, single-page, morbidity... | ['Adolescent', 'Adult', 'Aged', 'Centers for Disease Control and Prevention, U.S.', 'Child', 'Child, Preschool', 'Disasters', 'Electronic Health Records', 'Emergency Service, Hospital', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Morbidity', 'Patient Discharge', 'Population Surveillance', '... | 21,888,728 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['M01.060.406'], ['M01.060.406.448'], ['N06.230.100'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['N02.278.2... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The waxing and waning of mental disorders: evaluating the stability of syndromes of mental disorders in the population. | This article examines the stability of symptoms, syndromes, and diagnoses of specific anxiety and depressive disorders, as well as diagnostic shifts from one syndrome to another over time. Using retrospective and longitudinal prospective data from the baseline and first follow-up investigation (19.7 months later) of th... | ['Adolescent', 'Anxiety Disorders', 'Comorbidity', 'Depressive Disorder', 'Female', 'Follow-Up Studies', 'Germany', 'Humans', 'Longitudinal Studies', 'Male', 'Population Surveillance', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Reproducibility of Results', 'Retrospective Studies', 'Syn... | 10,746,914 | [['M01.060.057'], ['F03.080'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.600.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Rehabilitation of skiing injuries. | It is important to include psychological and physiologic rehabilitation in addition to rehabilitation of the injured area. Motion that does not stress repairs of either ligament or bone is not contraindicated. Exercises that aggravate patellofemoral problems should be modified to avoid areas in the range of motion that... | ['Athletic Injuries', 'Exercise Therapy', 'Fractures, Bone', 'Humans', 'Knee Injuries', 'Ligaments, Articular', 'Skiing', 'Sprains and Strains'] | 7,187,310 | [['C26.115'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['I03.450.642.845.787.500'], ['C26.844']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
The unrecognized burden of osteoporosis-related vertebral fractures in patients with heart failure. | BACKGROUND: Heart failure (HF) is associated with several factors that contribute to both reduced bone mineral density and increased risk of osteoporosis-related fractures. Our objectives were to describe the prevalence and predictors of the most common osteoporotic fracture, vertebral compression fractures (VCF), in p... | ['Aged', 'Aged, 80 and over', 'Atrial Fibrillation', 'Canada', 'Cost of Illness', 'Cross-Sectional Studies', 'Female', 'Heart Failure', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Osteoporotic Fractures', 'Prevalence', 'Radiography, Thoracic', 'Risk Factors'] | 21,558,449 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067.198', 'C23.550.073.198'], ['Z01.107.567.176'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C14.280.434'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Smartphone applications for pediatric anesthesia. | We present a review of smartphone applications (apps) available for pediatric anesthesia. | ['Anesthesia', 'Anesthesiology', 'Anesthetics', 'Cell Phone', 'Child', 'Computers, Handheld', 'Critical Care', 'Emergency Medical Services', 'Humans', 'Information Management', 'Pediatrics', 'Pharmaceutical Preparations', 'Software'] | 22,309,487 | [['E03.155'], ['H02.403.066'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['L01.178.847.698.300'], ['M01.060.406'], ['L01.224.230.260.550.500'], ['E02.760.190', 'N02.421.585.190'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.399'], ['H02.403.670'], ['D26'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Identification and characterization of two alternative splice variants of human interleukin-2. | Our previous work showed that alternative splicing is used to make an inhibitory variant of human interleukin (IL)-4. Because of homology between IL-4 and IL-2 proteins and receptors, we tested whether alternative splicing is used to generate similar inhibitory variants of human IL-2. Messenger RNA from peripheral bloo... | ['Alternative Splicing', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Genetic Variation', 'Humans', 'Interleukin-2', 'Lymphocyte Activation', 'Polymerase Chain Reaction', 'RNA, Messenger', 'Receptors, Interleukin-2', 'Sequence Analysis, DNA', 'T-Lymphocytes'] | 8,798,495 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Matching motivation enhancement treatment to client motivation: re-examining the Project MATCH motivation matching hypothesis. | AIMS: The current study was designed to re-examine the motivation matching hypothesis from Project MATCH using growth mixture modeling, an analytical technique that models variation in individual drinking patterns.DESIGN, SETTING AND PARTICIPANTS: Secondary data analyses of data from Project MATCH (n = 1726), a large m... | ['Aftercare', 'Alcohol Drinking', 'Alcoholism', 'Ambulatory Care', 'Attitude to Health', 'Cognitive Behavioral Therapy', 'Data Interpretation, Statistical', 'Female', 'Humans', 'Male', 'Models, Statistical', 'Motivation', 'Outcome and Process Assessment, Health Care', 'Patient Selection', 'Severity of Illness Index', '... | 20,491,723 | [['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['E02.760.106', 'N02.421.585.106'], ['F01.100.150', 'N05.300.150'], ['F04.754.137.350'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Extinction retention predicts improvement in social anxiety symptoms following exposure therapy. | BACKGROUND: Several researchers have argued that basic research on extinction learning can guide efforts to enhance the efficacy of exposure-based therapy. At the basis of this translational research paradigm is the assumption that extinction retention is important to the outcome of exposure-based therapy. This study i... | ['Adolescent', 'Adult', 'Avoidance Learning', 'Extinction, Psychological', 'Fear', 'Female', 'Humans', 'Implosive Therapy', 'Male', 'Phobic Disorders', 'Prognosis', 'Randomized Controlled Trials as Topic', 'Retention, Psychology', 'Treatment Outcome', 'Young Adult'] | 18,781,661 | [['M01.060.057'], ['M01.060.116'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.425.770.232'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.754.137.506.325'], ['F03.080.725'], ['E01.789'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surgical Treatments of Tumor-Induced Osteomalacia Lesions in Long Bones: Seventeen Cases with More Than One Year of Follow-up. | BACKGROUND: Tumor-induced osteomalacia is a rare and fascinating paraneoplastic syndrome usually caused by a small, benign phosphaturic mesenchymal tumor. Most tumors are treated surgically, but we are unaware of any reports that compare the results of curettage and segmental resection for lesions in long bones.METHODS... | ['Adult', 'Bone Neoplasms', 'Curettage', 'Female', 'Fibroblast Growth Factors', 'Follow-Up Studies', 'Humans', 'Leg Bones', 'Male', 'Middle Aged', 'Neoplasms, Connective Tissue', 'Osteotomy', 'Phosphorus', 'Retrospective Studies', 'Treatment Outcome', 'Ulna', 'Young Adult'] | 26,135,075 | [['M01.060.116'], ['C04.588.149', 'C05.116.231'], ['E04.157'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.650'], ['M01.060.116.630'], ['C04.557.450.56... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Co-occurrence of intracerebral tuberculoma with lumbar intramedullary tuberculoma. | Tuberculosis is common in India, but the co-occurrence of intracranial and intramedullary tuberculomas as a manifestation of central nervous system tuberculosis is extremely rare in children. We report a case of concurrent intracranial and lumbar intramedullary tuberculomas in a 6-year-old girl. The child developed the... | ['Antitubercular Agents', 'Brain', 'Child', 'Diagnosis, Differential', 'Edema', 'Female', 'Humans', 'Isoniazid', 'Lumbar Vertebrae', 'Magnetic Resonance Imaging', 'Rifampin', 'Spinal Cord', 'Spinal Diseases', 'Tomography, X-Ray Computed', 'Tuberculoma', 'Tuberculoma, Intracranial'] | 19,189,935 | [['D27.505.954.122.085.255'], ['A08.186.211'], ['M01.060.406'], ['E01.171'], ['C23.888.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['A02.835.232.834.519'], ['E01.370.350.825.500'], ['D03.633.400.811.700', 'D04.345.295.750.700'], ['A08.186.854'], ['C... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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