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Giant abdominal cysts simulating ascites. | In two patients ascites was suspected, but large intra-abdominal cysts were found on laparotomy. They were of echinococcal and ovarian origin, respectively. When there is doubt about the nature of such abdominal distention, abdominal paracentesis should be avoided and ultrasonography used instead. | ['Adolescent', 'Adult', 'Ascites', 'Diagnosis, Differential', 'Echinococcosis, Hepatic', 'Female', 'Humans', 'Ovarian Cysts'] | 7,234,832 | [['M01.060.057'], ['M01.060.116'], ['C23.550.081'], ['E01.171'], ['C01.610.335.190.396.314', 'C01.610.518.314', 'C06.552.664.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.182.612', 'C13.351.500.056.630.580', 'C19.391.630.580']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The implementation of a nationwide anomaly screening programme improves prenatal detection of major cardiac defects: an 11-year national population-based cohort study. | OBJECTIVE: To evaluate whether a nationwide prenatal anomaly screening programme improves detection rates of univentricular heart (UVH) and transposition of great arteries (TGA), and whether maternal risk factors for severe fetal heart disease affect prenatal detection.DESIGN: Population-based cohort study.SETTING: Nat... | ['Adult', 'Female', 'Fetal Diseases', 'Finland', 'Heart Defects, Congenital', 'Heart Ventricles', 'Humans', 'Infant, Newborn', 'Maternal Age', 'Pregnancy', 'Pregnancy Complications', 'Prenatal Diagnosis', 'Prevalence', 'Program Evaluation', 'Risk Factors', 'Transposition of Great Vessels'] | 30,576,052 | [['M01.060.116'], ['C13.703.277', 'C16.300'], ['Z01.542.816.186'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.560', 'N05.715.350.075.550', 'N06.850.490.250.550'], ['G08.686.784.769'], ['C13.703'], ['E01.370.378.630'... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pathways to conscience: early mother-child mutually responsive orientation and children's moral emotion, conduct, and cognition. | BACKGROUND: Associations between early mother-child mutually responsive orientation (MRO) and children's conscience have been previously established, but the mechanisms accounting for those links are not understood. We examined three such mediational mechanisms: (a) the child's enhanced enjoyment of interactions with t... | ['Child', 'Child Behavior', 'Child Development', 'Child, Preschool', 'Cognition', 'Consciousness', 'Emotions', 'Female', 'Humans', 'Infant', 'Male', 'Models, Psychological', 'Mother-Child Relations'] | 15,660,641 | [['M01.060.406'], ['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['F02.463.188'], ['F02.463.188.409', 'F02.830.233'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.599.695'], ['F01.829.263.370.290.170']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Novel bridge of axon-like processes of epithelial cells in the aboral sense organ of ctenophores. | We describe by light and electron microscopy a novel structure in the aboral sense organ (apical organ) of cydippid (Pleurobrachia) and lobate (Mnemiopsis) ctenophores. An elevated bundle of long, thin, microtubule-filled processes arises from the apical ends of two groups of epithelial cells located on opposite sides ... | ['Animals', 'Cell Polarity', 'Ctenophora', 'Electric Conductivity', 'Epithelial Cells', 'Larva', 'Microscopy, Electron', 'Models, Anatomic', 'Motor Activity', 'Sense Organs', 'Synapses'] | 12,353,295 | [['B01.050'], ['G04.250'], ['B01.050.500.325'], ['G01.358.500.249.277'], ['A11.436'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E01.370.350.515.402', 'E05.595.402'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['F01.145.632', 'G11.427.410.698'], ['A09'], ['A08.850', 'A11.284.149.165.420.780']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Rare Helicobacter pylori Virulence Genotypes in Bhutan. | Both the prevalence of Helicobacter pylori infection and the incidence of gastric cancer are high in Bhutan. The high incidence of atrophic gastritis and gastric cancer suggest the phylogeographic origin of an infection with a more virulent strain of H. pylori. More than 90% of Bhutanese strains possessed the highly vi... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Amino Acid Sequence', 'Antigens, Bacterial', 'Bacterial Proteins', 'Bhutan', 'Female', 'Genotype', 'Helicobacter pylori', 'Humans', 'Male', 'Middle Aged', 'Virulence', 'Young Adult'] | 26,931,643 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.161'], ['D12.776.097'], ['Z01.252.245.162'], ['G05.380'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G06... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
[Effect of flavonoid fractions of Solidago virgaurea L on diuresis and levels of electrolytes]. | The flavonoid fractions of Solidago virgaurea L.S. gigantea Ait., S. canadensis var. canadensis and S. canadensis var. "scabra" flowers were administrated p.o. to rats and showed diuretic activity. Increase in overnight diuresis reached 57-88%. Decrease of overnight excretion of potassium and sodium also occurred after... | ['Administration, Oral', 'Animals', 'Diuresis', 'Electrolytes', 'Flavonoids', 'Plants', 'Rats'] | 1,669,338 | [['E02.319.267.100'], ['B01.050'], ['G08.852.179'], ['D01.248'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B01.650'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visualizing the Balbiani Body in Zebrafish Oocytes. | Approaches to visualize the Balbiani body of zebrafish primary oocytes using protein, RNA, and mitochondrial markers are described. The method involves isolation, histology, staining, and microscopic examination of early zebrafish oocytes. These techniques can be applied to visualize gene products that are localized to... | ['Animals', 'Biomarkers', 'Endoplasmic Reticulum', 'Female', 'Fluorescent Antibody Technique', 'Immunohistochemistry', 'In Situ Hybridization', 'Mitochondria', 'Molecular Imaging', 'Oocytes', 'Oogenesis', 'RNA', 'Zebrafish'] | 30,737,697 | [['B01.050'], ['D23.101'], ['A11.284.430.214.190.875.248'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The function of self-harm behavior in a forensic population. | This article examines the functions of self-injurious behavior (SIB) in forensic populations. The cases of four individual offenders who have engaged in SIB are presented. These cases depict the four main functions of self-harm behaviors including (a) suicidal intent, (b) manipulation of the environment, (c) emotion re... | ['Adaptation, Psychological', 'Adult', 'Behavior Control', 'Delusions', 'Emotions', 'Female', 'Hallucinations', 'Humans', 'Male', 'Personality Assessment', 'Prisoners', 'Psychotic Disorders', 'Self-Injurious Behavior', 'Suicide, Attempted'] | 15,746,265 | [['F01.058'], ['M01.060.116'], ['E02.085', 'F04.047', 'I01.880.630.099'], ['F01.145.126.200'], ['F01.470'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.513'], ['M01.729'], ['F03.700.675'], ['F01.145.126.980'], ['F01.145.126.980.875.600', ... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide. | UNLABELLED: Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of choline results in the production of trimethylamine (TMA), which upon absorption by the host is converted in the liver to trimethylamine-N-oxide (TMAO). Recent studies revealed that TMAO exacerbates atherosclerosis in ... | ['Animals', 'Choline', 'Diet', 'Gastrointestinal Microbiome', 'Germ-Free Life', 'Humans', 'Methylamines', 'Mice', 'Microbiota', 'Molecular Sequence Data', 'Sequence Analysis, DNA'] | 25,784,704 | [['B01.050'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['G07.203.650.240'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['G06.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.668'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia. | Inhaled formaldehyde is classified as a known human and animal carcinogen, causing nasopharyngeal cancer. Additionally, limited epidemiological evidence for leukemia in humans is available; however, this is inconsistent across studies. Both genotoxicity and cytotoxicity are key events in formaldehyde nasal carcinogenic... | ['Animals', 'Chromatography, High Pressure Liquid', 'DNA Adducts', 'Formaldehyde', 'Inhalation Exposure', 'Leukemia', 'Male', 'Nose Neoplasms', 'Rats', 'Rats, Inbred F344', 'Spectrometry, Mass, Electrospray Ionization'] | 20,176,625 | [['B01.050'], ['E05.196.181.400.300'], ['D13.444.308.135', 'G05.200.104'], ['D02.047.407'], ['N06.850.460.350.112'], ['C04.557.337'], ['C04.588.149.721.600', 'C04.588.443.665.650', 'C05.116.231.754.600', 'C08.460.669', 'C08.785.600', 'C09.603.669', 'C09.647.685'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genomic parasites and genome evolution. | A report of the Second International Conference/Workshop on the Genomic Impact of Eukaryotic Transposable Elements, Pacific Grove, USA, 6-10 February 2009. | ['Animals', 'DNA Transposable Elements', 'Evolution, Molecular', 'Gene Expression Regulation', 'Gene Regulatory Networks', 'Genome', 'Humans', 'Mutagenesis, Insertional', 'Regulatory Sequences, Nucleic Acid'] | 19,435,480 | [['B01.050'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['G05.045.250', 'G16.075.250'], ['G05.308'], ['G05.360.080.689.360'], ['G05.360.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.420.601.550', 'G05.365.590.575', 'G05.558.550'], ['G02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Echocardiographic Stress Test with Adenosine Triphosphate: Optimization of the Algorithm]. | PURPOSE: To: 1) optimize algorithm of stress echocardiography (s-Echo) with intravenous adenosine triphosphate (ATP) infusion taking into account pharmacokinetics and pharmacodynamics of ATP in human body, 2) test new algorithm in patients with coronary and other heart diseases.MATERIALS AND METHODS: In order to determ... | ['Adenosine Triphosphate', 'Algorithms', 'Coronary Angiography', 'Echocardiography', 'Exercise Test', 'Humans'] | 31,849,298 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G17.035', 'L01.224.050'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.250', 'E01.370.386.700.25... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pubertal ovarian hormone exposure reduces the number of myelinated axons in the splenium of the rat corpus callosum. | The size of the female rat corpus callosum decreases in response to pubertal ovarian hormone exposure, but the underlying changes in axonal composition have not been examined. In the current study, animals underwent ovariectomy or sham surgery at day 20, and the number of myelinated and unmyelinated axons were examined... | ['Animals', 'Axons', 'Body Weight', 'Corpus Callosum', 'Female', 'Image Processing, Computer-Assisted', 'Microscopy, Electron, Transmission', 'Myelin Sheath', 'Ovariectomy', 'Rats', 'Rats, Long-Evans', 'Sexual Maturation'] | 17,963,756 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211.200.885.800.750'], ['L01.224.308'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['A08.637.600.500... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
It feels like yesterday: self-esteem, valence of personal past experiences, and judgments of subjective distance. | Supporting predictions from temporal self-appraisal theory, participants in 3 studies reported feeling farther from former selves and experiences with unfavorable implications for their current self-view than from equally distant selves and experiences with flattering implications. This distancing bias occurred when as... | ['Achievement', 'Adolescent', 'Adult', 'Female', 'Humans', 'Individuality', 'Judgment', 'Male', 'Mental Recall', 'Motivation', 'Psychological Distance', 'Self Concept', 'Students'] | 12,003,478 | [['F01.658.059', 'F02.784.629.054'], ['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F02.463.785.626'], ['F02.463.425.540.641'], ['F01.658', 'F01.752.543.500.750'], ['F01.145.813.630', 'F01.829.316.777'], ['F01.752.747.792'], ['M01.848']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Problems of isolating Borrelia burgdorferi from ticks collected in United Kingdom foci of Lyme disease. | Many isolates of Borrelia burgdorferi have been obtained from ticks and vertebrate tissues collected in North America and continental Europe but only one established culture of United Kingdom Borrelia burgdorferi has been recorded. In this paper we report the isolation of B. burgdorferi from one of 108 tick pools repre... | ['Animals', 'Animals, Wild', 'Base Sequence', 'Borrelia burgdorferi Group', 'DNA Primers', 'DNA, Bacterial', 'Europe', 'Fluorescent Antibody Technique', 'Humans', 'Lyme Disease', 'Mammals', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Ticks', 'United Kingdom'] | 8,025,327 | [['B01.050'], ['B01.050.050.300'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.425.410.711.193.150', 'B03.851.595.193.150'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.212'], ['Z01.542'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Which patients are seen by an occupational psychiatry service? | BACKGROUND: Common mental disorders are the leading cause of sickness absence but are frequently misdiagnosed and undertreated. It is against this background that a specialist occupational psychiatry clinic was established at a London teaching hospital.AIMS: To explore the nature of patients and complaints seen in the ... | ['Adolescent', 'Adult', 'Ambulatory Care Facilities', 'Delivery of Health Care', 'Depression', 'Depressive Disorder', 'Female', 'Humans', 'London', 'Male', 'Mental Disorders', 'Middle Aged', 'Occupational Health Services', 'Primary Health Care', 'Psychiatry', 'Retrospective Studies', 'Secondary Care', 'Sick Leave', 'Yo... | 23,990,507 | [['M01.060.057'], ['M01.060.116'], ['N02.278.035'], ['N04.590.374', 'N05.300'], ['F01.145.126.350'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.433.553', 'Z01.542.363.300.553'], ['F03'], ['M01.060.116.630'], ['N02.421.143.740'], ['N04.590.233.727'], ['F04.096.544', 'H02.403.690'], ['E05.318... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Oxygen uptake and filtration rate as animal health biomarker in Lamellidens marginalis (Lamarck). | The freshwater bivalve, L. marginalis was experimentally exposed to 10 and 30 ppm concentrations of CdCl2 to examine filtration rate, oxygen uptake and glycogen level of liver and gills for health assessment for their reuse in the reclamation of cadmium intoxicated environments. In situ experiment was also performed fo... | ['Animals', 'Biomarkers', 'Bivalvia', 'Cadmium Chloride', 'Environmental Exposure', 'Filtration', 'Gills', 'Glycogen', 'Liver', 'Oxygen', 'Oxygen Consumption'] | 15,332,502 | [['B01.050'], ['D23.101'], ['B01.050.500.644.080'], ['D01.142.175', 'D01.210.450.150.125'], ['N06.850.460.350'], ['E05.196.454', 'G01.280', 'G02.263'], ['A13.421'], ['D05.750.078.562.388', 'D09.698.365.388'], ['A03.620'], ['D01.268.185.550', 'D01.362.670'], ['G03.680']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Foot-and-mouth disease virus causes a decrease in spleen dendritic cells and the early release of IFN-á in the plasma of mice. Differences between infectious and inactivated virus. | Foot-and-mouth disease (FMD) is a highly contagious and acute viral disease of cloven-hoofed animals. From an economical point of view, it is the most important disease of livestock worldwide. It is known that the virus interacts with dendritic cells, both in the natural host and in mice, but the impact of this interac... | ['Animals', 'Dendritic Cells', 'Foot-and-Mouth Disease', 'Foot-and-Mouth Disease Virus', 'Interferon-alpha', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Spleen'] | 22,387,627 | [['B01.050'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C01.925.782.687.484', 'C22.380'], ['B04.820.578.750.070.250'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.250'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B0... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential methylation of the OCT3/4 upstream region in primary human testicular germ cell tumors. | Germ cell tumors show many similarities to normal embryogenesis. This is, for example, illustrated by the expression of the marker of pluripotency, OCT3/4, known to play a pivotal role in the early stages of normal development. Interestingly, it is found to be the most informative diagnostic marker for the early develo... | ['Adult', 'Biomarkers, Tumor', 'Carcinoma, Embryonal', 'Cells, Cultured', 'DNA Methylation', 'DNA, Neoplasm', 'Endodermal Sinus Tumor', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'Neoplasms, Germ Cell and Embryonal', 'Octamer Transcription Factor-3', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Semi... | 17,549,357 | [['M01.060.116'], ['D23.101.140'], ['C04.557.465.200'], ['A11.251'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.444.308.425'], ['C04.557.465.510.350'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465'], ['D12.776.260.655.500.300', 'D12.776.930.710.500.300... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A journey towards a healthy collaborative nursing program: a case study. | In Canada, collaborative college-university nursing programs have emerged in response to professional education changes and nursing shortages. Developing a collaborative nursing education program between two provinces, each with a distinct academic culture, independent practice, unique governance and separate administr... | ['Canada', 'Cooperative Behavior', 'Education, Nursing, Baccalaureate', 'Education, Nursing, Graduate', 'Humans', 'Leadership', 'Models, Educational', 'Models, Organizational', 'Ontario', 'Program Development'] | 18,536,544 | [['Z01.107.567.176'], ['F01.145.813.115'], ['I02.358.462.316'], ['I02.358.337.450', 'I02.358.462.565'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['E05.599.545', 'I02.903.302'], ['E05.599.670', 'N04.452.534'], ['Z01.107.567.176.639'], ['N04.452.760']] | ['Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
2-Benzoylbenzofuran derivatives possessing piperazine linker as anticancer agents. | A series of novel 2-benzoylbenzofuran derivatives possessing piperazine linker have been prepared, and their in vitro anticancer activity against a panel of human tumor cell lines by MTT assay were evaluated. The results demonstrated that tertiary amine derivatives exhibited better cytotoxic activity, and SAR study rev... | ['Antineoplastic Agents', 'Apoptosis', 'Benzofurans', 'Cell Line, Tumor', 'Drug Screening Assays, Antitumor', 'Humans', 'Molecular Structure', 'Piperazines', 'Structure-Activity Relationship'] | 30,709,651 | [['D27.505.954.248'], ['G04.146.954.035'], ['D03.633.100.127'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['D03.383.606'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone is beneficial but toxic in very elderly patients with diffuse large B-cell lymphoma: a population-based cohort study on treatment, toxicity and outcome. | To assess treatment strategies, toxicity and outcome in very elderly patients (aged ? 75 years) diagnosed with diffuse large B-cell lymphoma (DLBCL) in the rituximab era, an observational population-based cohort study was performed. From 103 patients with a median age of 81 years, data of clinical characteristics, trea... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Antibodies, Monoclonal, Murine-Derived', 'Antineoplastic Combined Chemotherapy Protocols', 'Cause of Death', 'Cohort Studies', 'Cyclophosphamide', 'Doxorubicin', 'Female', 'Follow-Up Studies', 'Humans', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'Neoplasm Staging', 'Prednis... | 23,734,653 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400... | ['Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The influence of anatomic location on functional outcome in lower-extremity soft-tissue sarcoma. | BACKGROUND: The purpose of this study was to explore the relationship between the anatomical location of lower-extremity soft-tissue sarcoma and functional outcome.METHODS: Function was evaluated with the Musculoskeletal Tumor Society (MSTS 1993) score and Toronto Extremity Salvage Score (TESS); 207 patients (median ag... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Disabled Persons', 'Female', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Quality of Life', 'Risk Factors', 'Sarcoma', 'Soft Tissue Neoplasms', 'Treatment Outcome'] | 15,078,635 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Humanities [K]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Ectopic Myoglobin Expression Is Associated with a Favourable Outcome in Head and Neck Squamous Cell Carcinoma Patients. | BACKGROUND/AIM: Ectopic myoglobin (MB) expression, mediated by alternative and hypoxia-inducible transcription, has recently been demonstrated in several epithelial tumours. This study aimed to examine the expression of MB in hormone-independent head and neck squamous cell carcinomas (HNSCCs).PATIENTS AND METHODS: Usin... | ['Adolescent', 'Adult', 'Carcinoma, Squamous Cell', 'Child', 'Child, Preschool', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Myoglobin', 'Treatment Outcome', 'Young Adult'] | 27,919,941 | [['M01.060.057'], ['M01.060.116'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['M01.060.406'], ['M01.060.406.448'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.116.630'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['E01.789.800', 'N04.761.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Perception of control during episodes of eating: relationships with quality of life and eating psychopathology. | OBJECTIVE: Experience of loss of control (LOC) during eating is an important indicator of pathology, although this concept has not received a great deal of research attention. The present study explores how quality of life (QoL) is related to LOC during eating.METHOD: Three hundred and thirty-nine female university stu... | ['Adolescent', 'Adult', 'Bulimia', 'Feeding Behavior', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Perception', 'Quality of Life'] | 21,344,466 | [['M01.060.057'], ['M01.060.116'], ['C23.888.821.645.500'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The PXR is a drug target for chronic inflammatory liver disease. | UNLABELLED: PXR activators are used to treat pruritus in chronic inflammatory liver diseases such as primary biliary cirrhosis (PBC). The aims of this study were to determine whether PXR activators could have an additional benefit of inhibiting inflammation in the liver, and determine whether cyclosporin A - which more... | ['Animals', 'Cell Line', 'Cyclosporine', 'Female', 'Gene Expression Regulation', 'Hepatitis, Chronic', 'Humans', 'Liver Cirrhosis, Biliary', 'Mice', 'Mice, Knockout', 'NF-kappa B', 'Pregnane X Receptor', 'Receptors, Steroid', 'Tumor Necrosis Factor-alpha'] | 20,416,375 | [['B01.050'], ['A11.251.210'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G05.308'], ['C06.552.380.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.130.120.135.250.250', 'C06.552.150.250', 'C06.552.630.400', 'C23.550.355.412.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.5... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Catecholamine-stimulated cyclic AMP formation in phenylethanolamine N-methyltransferase containing brain stem nuclei of normal rats and of rats with spontaneous genetic hypertension. | Stimultaion of cyclic AMP formation by epinephrine and norepinephrine has been studied in discrete areas of rat brain that include the epinephrine-containing brain stem nuclei C-1 and C-2. In the C-1 area, epinephrine-stimulated cyclic AMP formation was partially reversed by 100 microM phentolamine and by 10--100 micro... | ['Adrenergic alpha-Antagonists', 'Adrenergic beta-Antagonists', 'Animals', 'Brain Stem', 'Cyclic AMP', 'Epinephrine', 'Hypertension', 'Male', 'Norepinephrine', 'Phenylethanolamine N-Methyltransferase', 'Rats', 'Receptors, Cholinergic'] | 6,101,988 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['A08.186.211.132'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells. | PURPOSE: Bcl-xL overexpression is common in head and neck squamous cell carcinomas (HNSCC) and correlates with resistance to chemotherapy. Thus, a nonpeptidic, cell-permeable small molecule that mimics the BH3 domain of proapoptotic proteins may inhibit Bcl-xL function and have therapeutic potential for HNSCC by overco... | ['Apoptosis', 'Blotting, Western', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Dimerization', 'Dose-Response Relationship, Drug', 'Drug Resistance', 'Fibroblasts', 'Gossypol', 'Head and Neck Neoplasms', 'Humans', 'In Situ Nick-End Labeling', 'Inhibitory Concentration 50', 'Pe... | 15,570,010 | [['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G02.206', 'G03.230'], ['G07.690.773.875', 'G07.690.936... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Doppler emboli signals vary according to stroke subtype. | BACKGROUND AND PURPOSE: Doppler ultrasound detection of emboli signals may assist in distinguishing embolic from thrombotic stroke. Selected patient groups have a high incidence of such signals. We have examined consecutive stroke cases to identify the incidence of Doppler emboli in different etiologic subtypes of stro... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arteriosclerosis', 'Carotid Stenosis', 'Cerebral Arterial Diseases', 'Cerebrovascular Disorders', 'Female', 'Humans', 'Incidence', 'Intracranial Embolism and Thrombosis', 'Male', 'Middle Aged', 'Time Factors', 'Ultrasonography, Doppler, Transcranial'] | 7,905,679 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['C10.228.140.300.510.200', 'C14.907.253.560.200'], ['C10.228.140.300', 'C14.907.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375',... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Lived Experience of Providing Care and Support Services for Holocaust Survivors in Australia. | Lack of awareness among paid carers of the possible late-life consequences of early-life periods of extreme and prolonged traumatization may have negative impacts on the experiences of trauma survivors in receiving care. An interpretive phenomenological approach was used to investigate the lived experience of paid care... | ['Australia', 'Caregivers', 'Emotions', 'Female', 'Focus Groups', 'Health Knowledge, Attitudes, Practice', 'Holocaust', 'Humans', 'Male', 'Psychological Trauma', 'Survivors'] | 27,634,292 | [['Z01.639.100', 'Z01.678.100.373'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F01.470'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.100.150.500', 'N05.300.150.410'], ['I01.198.240.903.149.500', 'I01.880.735.950.500.903.149.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F... | ['Geographicals [Z]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Predominance of syntrophic bacteria, Methanosaeta and Methanoculleus in a two-stage up-flow anaerobic sludge blanket reactor treating coffee processing wastewater at high organic loading rate. | The effect of the organic loading rate (OLR) on the performance and microbial composition of a two-stage UASB system treating coffee processing wastewater was assessed. The system was operated with OLR up to 18.2 g COD (L d)-1 and effluent recirculation. Methane production and effluent characteristics were monitored. T... | ['Anaerobiosis', 'Bacteria', 'Bioreactors', 'Coffee', 'Methane', 'Methanomicrobiaceae', 'Sewage', 'Waste Disposal, Fluid', 'Waste Water'] | 30,077,172 | [['G02.111.062', 'G03.078'], ['B03'], ['E07.115', 'J01.897.120.115'], ['D20.215.784.249', 'G07.203.100.325', 'J02.200.325'], ['D02.455.326.146.571'], ['B02.200.705.500'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.710.865']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Foxp3 is a novel repressor of microglia activation. | Forkhead transcription factor 3 (Foxp3) is critical for generating CD4(+)CD25(+) regulatory T cells. However, its role in microglia has not been identified. Here, we show that Foxp3 is expressed in microglia and is upregulated upon activation. In Foxp3 mutant mice (Foxp3(sf)), microglia release higher levels of inflamm... | ['Active Transport, Cell Nucleus', 'Animals', 'Cell Count', 'Cell Line', 'Cells, Cultured', 'Cerebral Cortex', 'Chemokine CCL2', 'Chemokine CXCL10', 'Forkhead Transcription Factors', 'I-kappa B Proteins', 'Lipopolysaccharides', 'Mice', 'Mice, Transgenic', 'Microglia', 'NF-KappaB Inhibitor alpha', 'NF-kappa B', 'Nitric ... | 20,544,860 | [['G03.143.310.100', 'G03.143.700.100'], ['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.251.210'], ['A11.251'], ['A08.186.211.200.885.287.500'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Respiration of avian embryos - a comparative analysis. | All published values of the metabolic rates of avian embryos are brought together for analysis. A generalized pattern of O2 consumption during development of precocial eggs is determined and used to estimate the total amount of O2 consumed duirng development. The metabolic rates of avian eggs just prior to internal pip... | ['Animals', 'Birds', 'Carbon Dioxide', 'Chick Embryo', 'Columbidae', 'Embryo, Nonmammalian', 'Oxygen', 'Oxygen Consumption', 'Partial Pressure', 'Time Factors'] | 6,770,428 | [['B01.050'], ['B01.050.150.900.248'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.165.150'], ['A13.350', 'A16.331'], ['D01.268.185.550', 'D01.362.670'], ['G03.680'], ['G01.374.715.714'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ca(2+)-dependent, myosin subfragment 1-induced proximity changes between actin and the inhibitory region of troponin I. | In order to help understand the spatial rearrangements of thin filament proteins during the regulation of muscle contraction, we used fluorescence resonance energy transfer (FRET) to measure Ca(2+)-dependent, myosin-induced changes in distances and fluorescence energy transfer efficiencies between actin and the inhibit... | ['Actins', 'Animals', 'Calcium', 'Energy Transfer', 'Fluorescent Dyes', 'Muscle, Skeletal', 'Myosin Subfragments', 'Myosins', 'Naphthalenesulfonates', 'Rabbits', 'Troponin I'] | 11,690,651 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A02.633.567', 'A10.690.552.500'], ['D05.750.078.730.475.300', 'D12.776.210.500.600.300'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Meeting the need for public education about dementia. | Research continues to advance the knowledge of pathophysiology and development of effective methods for treating patients with Alzheimer disease and other dementias. Dissemination of information is likely to be slowest among the general population, who may be the first to recognize dementia symptoms but may also be ret... | ['Aged', 'Caregivers', 'Data Collection', 'Dementia', 'Education', 'Family Health', 'Health Services Needs and Demand', 'Hotlines', 'Humans', 'Information Services', 'Referral and Consultation'] | 11,236,822 | [['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['C10.228.140.380', 'F03.615.400'], ['I02'], ['N01.400.300'], ['N03.349.380.420', 'N05.300.450'], ['N02.421.297.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453'], ... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Dual role of inducible nitric oxide synthase in acute asbestos-induced lung injury. | Reactive oxygen and nitrogen species have been implicated in the pathogenesis of asbestos fibers-associated pulmonary diseases. By comparing the responses of inducible nitric oxide synthase (iNOS) knockout and wild-type mice we investigated the consequences of iNOS expression for the development of the inflammatory res... | ['Acute Disease', 'Animals', 'Asbestos', 'Asbestosis', 'Bronchoalveolar Lavage Fluid', 'Chemotaxis', 'Enzyme Induction', 'Gene Expression Regulation', 'Inflammation', 'L-Lactate Dehydrogenase', 'Lung', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Neutrophils', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitric Oxide ... | 12,160,931 | [['C23.550.291.125'], ['B01.050'], ['D01.578.725.050', 'D01.837.725.700.760.070'], ['C08.381.483.581.125', 'C08.381.520.702.125', 'C24.800.127'], ['E05.927.100.500'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['G05.308.320.200'], ['G05.308'], ['... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognostic significance of electrocardiographic abnormalities in diphtheritic myocarditis after hospital discharge: a long-term follow-up study. | OBJECTIVE: We aimed to investigate the long-term cardiac mortality and the relationship between cardiac mortality and electrocardiographic abnormalities in patients with diphtheritic myocarditis who survived after hospital discharge.MATERIALS AND METHODS: Between 1991 and 1996, 32 patients (all males, mean age 21.00 +/... | ['Adult', 'Cause of Death', 'Diphtheria', 'Echocardiography', 'Electrocardiography', 'Follow-Up Studies', 'Humans', 'Longitudinal Studies', 'Male', 'Military Personnel', 'Myocarditis', 'Patient Discharge', 'Prognosis', 'Proportional Hazards Models', 'Survival Rate'] | 16,472,279 | [['M01.060.116'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C01.150.252.410.040.246.388'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cell quality of apheresis-derived platelets treated with riboflavin-ultraviolet light after resuspension in platelet additive solution. | BACKGROUND: Previously, we evaluated the Mirasol pathogen reduction technology (PRT) system on platelet (PLT) function before resuspension. We now evaluated this system in the presence of PLT additive solution (PAS).STUDY DESIGN AND METHODS: Double-dose PLTs (n = 15) were generated using a commercially available aphere... | ['Adenosine Triphosphate', 'Blood Platelets', 'Blood Preservation', 'Cell Survival', 'Glucose', 'Humans', 'L-Lactate Dehydrogenase', 'Lactic Acid', 'Membrane Potential, Mitochondrial', 'Osmotic Pressure', 'Oxygen Consumption', 'Photosensitizing Agents', 'Plateletpheresis', 'Riboflavin', 'Solutions', 'Ultraviolet Rays'] | 21,981,030 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.118.188', 'A15.145.229.188'], ['E02.792.833.230', 'E05.760.833.230'], ['G04.346'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['D02.241.511.459.450... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Changing tides: Adaptive monitoring, assessment, and management of pharmaceutical hazards in the environment through time. | Pharmaceuticals are ubiquitous contaminants in aquatic ecosystems. Adaptive monitoring, assessment, and management programs will be required to reduce the environmental hazards of pharmaceuticals of concern. Potentially underappreciated factors that drive the environmental dose of pharmaceuticals include regulatory app... | ['Antidepressive Agents', 'Ecosystem', 'Environmental Monitoring', 'Hazardous Substances', 'Time Factors', 'Water Pollutants, Chemical', 'Water Quality'] | 26,412,644 | [['D27.505.954.427.700.122'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.426'], ['G01.910.857'], ['D27.888.284.903.655'], ['N06.850.460.350.080.750', 'N06.850.460.790.730']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Hydrogen peroxide in the troposphere]. | The past few decades saw a rising interest in the role of hydrogen peroxide (H2O2) in atmospheric chemistry and its contribution to the formation of free radicals. Free radicals (oxidants) are formed by photochemical reactions between ozone and H2O2. Free radicals formed within cells can oxidise biomolecules, and this ... | ['Air Pollutants', 'Atmosphere', 'Free Radicals', 'Hydrogen Peroxide', 'Oxidants, Photochemical'] | 17,562,608 | [['D27.888.284.101'], ['G16.500.275.063', 'N06.230.300.100'], ['D01.339', 'D02.389'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D27.720.642.631', 'D27.888.569.540.631']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Catalytic ozonation of 2,4-dichlorophenoxyacetic acid using alumina in the presence of a radical scavenger. | Using a laboratory-scale mixed reactor, the performance of alumina in degrading 2,4-Dichlorophenoxyacetic acid with ozone in the presence of tert-butyl alcohol radical scavenger was studied. The operating variables investigated were the dose of alumina catalyst and solution pH. Results showed that using ozone and alumi... | ['2,4-Dichlorophenoxyacetic Acid', 'Adsorption', 'Aluminum Oxide', 'Catalysis', 'Free Radical Scavengers', 'Herbicides', 'Kinetics', 'Ozone'] | 22,494,378 | [['D02.241.081.018.386.682.224', 'D02.241.511.316.682.149'], ['G01.030', 'G02.020'], ['D01.056.050', 'D01.650.550.050'], ['G02.130'], ['D27.505.519.217.500'], ['D27.720.031.700.366', 'D27.888.723.366'], ['G01.374.661', 'G02.111.490'], ['D01.362.670.600']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative proteomic analysis of chromatin-associated factors. | A method to identify and quantify chromatin-associated proteins has been developed and applied to the analysis of changes in chromatin-associated proteins induced by Myc oncoprotein expression in human B lymphocytes. Chromatin-enriched fractions were isolated by differential detergent/salt extraction and analyzed by IC... | ['B-Lymphocytes', 'Cell Line', 'Chromatin', 'Chromosomal Proteins, Non-Histone', 'Genes, myc', 'Humans', 'Nuclear Proteins', 'Proteome', 'Up-Regulation'] | 12,837,591 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.251.210'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.660.235', 'D12.776.664.235'], ['G05.360.340.024.340.375.500.791.420'], ['B01.050.150.900.649... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Diagnosis and therapy of plasmacytoma and Waldenstrom's disease]. | Plasmocytoma and Waldenstroem's disease together with some other very rare diseases form the group of paraproteinaemic haemoblastoses. In these cases the plasmocytoma as a neoplasia of the plasma cells is quite likely to define by the sum of the cytomorphological, radiological and immunological findings in form of the ... | ['Antibody Formation', 'Antineoplastic Agents', 'Bence Jones Protein', 'Humans', 'Immunoelectrophoresis', 'Immunoglobulins', 'Plasmacytoma', 'Waldenstrom Macroglobulinemia'] | 822,613 | [['G12.450.050.370.250'], ['D27.505.954.248'], ['D12.776.124.486.485.900.120', 'D12.776.124.790.651.900.120', 'D12.776.377.715.548.900.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350.350', 'E05.196.401.568', 'E05.200.812.735.645.350.350', 'E05.301.300.568', 'E05.478.594.760.645.350... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intensive care unit admissions and ventilation support in infants with bronchiolitis. | OBJECTIVES: To describe the rate of intensive care unit (ICU) admission, type of ventilation support provided and risk factors for ICU admission in infants with bronchiolitis.DESIGN: Retrospective review of hospital records and Australia and New Zealand Paediatric Intensive Care (ANZPIC) registry data for infants 2-12 ... | ['Australia', 'Bronchiolitis', 'Cannula', 'Continuous Positive Airway Pressure', 'Female', 'Humans', 'Infant', 'Intensive Care Units', 'Male', 'New Zealand', 'Noninvasive Ventilation', 'Patient Admission', 'Respiration, Artificial', 'Retrospective Studies'] | 28,544,539 | [['Z01.639.100', 'Z01.678.100.373'], ['C01.748.099.135', 'C08.127.446.135', 'C08.381.495.146.135', 'C08.730.099.135'], ['E07.132.125'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['N02.278.388.493'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E02.041... | ['Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Physical activity and cognitive function among older adults with hypertension. | OBJECTIVE: We evaluated the specific association between physical activity and cognitive function among a national sample of the broader US adult population with evidence of systemic hypertension.METHODS: Data from the 1999-2002 National Health and Nutrition Examination Survey were used to identify 1554 older adults, a... | ['Aged', 'Cholesterol, HDL', 'Cognition', 'Exercise', 'Female', 'Humans', 'Hypertension', 'Linear Models', 'Male', 'Nutrition Surveys', 'United States'] | 28,221,197 | [['M01.060.116.100'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['F02.463.188'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.75... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Inhibitory discriminative control is specific to both the response and the reinforcer. | In two experiments an S delta was established which signalled the absence of an instrumental contingency between a particular response, R1, and a particular reinforcer, Rf1. The S delta suppressed operant responding, and the specificity of this suppression to the elements of the response-reinforcer association, R1 and ... | ['Animals', 'Association Learning', 'Conditioning, Classical', 'Discrimination Learning', 'Inhibition, Psychological', 'Learning', 'Male', 'Motivation', 'Rats', 'Rats, Inbred Strains'] | 2,798,926 | [['B01.050'], ['F02.463.425.069.296'], ['F02.463.425.179.308'], ['F02.463.425.280'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F02.463.425', 'F02.784.629.529'], ['F01.658', 'F01.752.543.500.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Yeast metallothionein function in metal ion detoxification. | A genetic approach was taken to test the function of yeast metallothionein in metal ion detoxification. A yeast strain was constructed in which the metallothionein locus was deleted (cup1 delta). The cup1 delta strain was complemented with normal or mutant metallothionein genes under normal or constitutive regulatory c... | ['Amino Acid Sequence', 'Base Sequence', 'Genes', 'Genes, Fungal', 'Metallothionein', 'Metals', 'Mutation', 'Plasmids', 'Saccharomyces cerevisiae'] | 3,536,930 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D12.776.556.670'], ['D01.552'], ['G05.365.590'], ['G05.360.600'], ['B01.300.107.795.785.800', 'B01.300... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Aluminum resistance in the Arabidopsis mutant alr-104 is caused by an aluminum-induced increase in rhizosphere pH. | A mechanism that confers increased Al resistance in the Arabidopsis thaliana mutant alr-104 was investigated. A modified vibrating microelectrode system was used to measure H+ fluxes generated along the surface of small Arabidopsis roots. In the absence of Al, no differences in root H+ fluxes between wild type and alr-... | ['Aluminum', 'Arabidopsis', 'Drug Resistance', 'Hydrogen-Ion Concentration', 'Ion-Selective Electrodes', 'Microelectrodes', 'Mutation', 'Plant Roots', 'Vibration'] | 9,576,770 | [['D01.268.557.050', 'D01.552.547.050'], ['B01.650.940.800.575.912.250.157.100'], ['G07.690.773.984'], ['G02.300'], ['E07.305.250.471'], ['E07.305.250.500'], ['G05.365.590'], ['A18.400'], ['G01.374.930']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene therapy for experimental brain tumors using a xenogenic cell line engineered to secrete hIL-2. | Local delivery of cytokines has been shown to have a potent anti-tumor activity against a wide range of malignant brain tumors. In this study, we examined the feasibility and efficacy of using a rat endothelial cell line (NTC-121) transfected with the human interleukin-2 (IL-2) gene in treating experimental murine CNS ... | ['Animals', 'Antibody Formation', 'Brain Neoplasms', 'CD8-Positive T-Lymphocytes', 'Cell Line', 'Cell Transplantation', 'Endothelium', 'Genetic Therapy', 'Humans', 'Immunotherapy', 'Injections', 'Interleukin-2', 'Melanoma', 'Mice', 'Rats', 'Survival Analysis', 'Transplantation, Heterologous'] | 12,952,296 | [['B01.050'], ['G12.450.050.370.250'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['A11.251.210'], ['E02.095.147.500', 'E04.936.225'], ['A10.272.491'], ['E02.095.301', 'E05.393.420.301'], ['B01.050.150... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A more effective TR systematic biopsy of the prostate associated with power doppler ultrasonography (PDU): technical and morphological aspects. | OBJECTIVES: It is by now ascertained how PDU improves the effectiveness of systematic biopsy of the prostate. We have attempted to find better technical and imaging methods to optimise results.MATERIAL AND METHODS: We associated echo-biopsy with PDU on 131 patients. 64 patients (48.85%) showed prostate Ca. Their age wa... | ['Aged', 'Aged, 80 and over', 'Biopsy, Needle', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Prostate', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Rectum', 'Ultrasonography, Doppler'] | 16,444,928 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Integration of posture and movement: contributions of Sherrington, Hess, and Bernstein. | Neural mechanisms that integrate posture with movement are widespread throughout the central nervous system (CNS), and they are recruited in patterns that are both task- and context-dependent. Scientists from several countries who were born in the 19th century provided essential groundwork for these modern-day concepts... | ['Affect', 'Awareness', 'Central Nervous System', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Motor Cortex', 'Movement', 'Neurosciences', 'Posture', 'Pyramidal Tracts', 'Russia', 'Somatosensory Cortex', 'United Kingdom', 'Visceral Afferents'] | 16,337,298 | [['F01.470.047'], ['F02.463.188.150'], ['A08.186'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['G07.568', 'G11.427.410'], ['H01.158.610'], ['G11.427.695'], ['A08.186.854.300', 'A08.612.380.73... | ['Psychiatry and Psychology [F]', 'Anatomy [A]', 'Humanities [K]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Genetic and molecular analyses of the interaction between the flagellum-specific sigma and anti-sigma factors in Salmonella typhimurium. | More than 50 genes are required for flagellar formation and function in Salmonella typhimurium. According to the cascade model of flagellar regulon, the flagellar operons are divided into three classes, 1, 2, and 3, with respect to transcriptional hierarchy. FliA is an alternative sigma factor specific for transcriptio... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Flagella', 'Genetic Linkage', 'Molecular Sequence Data', 'Mutation', 'Operon', 'Protein Binding', 'Recombinant Fusion Proteins', 'Salmonella typhimurium', 'Sequence Analysis, DNA', 'Sigma Factor'] | 7,925,298 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['A11.284.180.290'], ['G05.348'], ['L01.453.245.667'], ['G05.365.590'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G02.111.679', 'G03.808'], ['D12.776.828.300'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760'], ['E05.393.760.700'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Slow inward current in aggregates of neonatal rat heart cells and its contribution to the steady state current-voltage relationship. | In voltage clamped neonatal rat heart cells a transient current is observed during depolarizing potential steps, which was identified as slow inward current (Isi) by its range of activation, by its reversal potential of approximately +50 mV and by its sensitivity to D600 or low external Ca2+. This Isi activates too fas... | ['Animals', 'Animals, Newborn', 'Electric Conductivity', 'Homeostasis', 'Kinetics', 'Mathematics', 'Myocardium', 'Rats', 'Rats, Inbred Strains'] | 6,889,094 | [['B01.050'], ['B01.050.050.282'], ['G01.358.500.249.277'], ['G07.410'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of thermocycling on nickel release from orthodontic arch wires: an in vitro study. | The amount of daily intake of metals from orthodontic appliances over time is a matter of great concern. Nickel results in one of the most common metal-induced allergic contact dermatitis in humans; it produces more allergic reactions than all the other metals combined together. The purpose of this study was to evaluat... | ['Humans', 'Hydrogen-Ion Concentration', 'Nickel', 'Orthodontic Wires', 'Temperature'] | 25,262,019 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['E06.658.453.684'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Carcinomatous lymphangitis as the initial manifestation of ovarian adenocarcinoma. | Carcinomatous lymphangitis accounts for approximately 8% of all cases of metastatic pulmonary tumors. The most common primary sites are breast, lung, stomach, prostate and pancreas. We describe herein the case of a 42-year-old woman in whom the first manifestation of an ovarian adenocarcinoma was carcinomatous lymphang... | ['Adenocarcinoma', 'Adult', 'Biopsy', 'Bronchoscopy', 'Female', 'Humans', 'Lung Neoplasms', 'Lymphangitis', 'Ovarian Neoplasms', 'Tomography, X-Ray Computed', 'Ultrasonography', 'Vagina'] | 18,026,661 | [['C04.557.470.200.025'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dengue Knowledge, Attitudes, and Practices Among Arizona Health Care Providers, 2014-2015. | Background: Detection of local dengue transmission requires an aware and engaged medical community, as health care providers are the front line of public health surveillance. To assess the knowledge, attitude, and practice about dengue, an online survey was distributed among Arizona health care providers during 2014 an... | ['Arizona', 'Data Collection', 'Dengue', 'Health Knowledge, Attitudes, Practice', 'Health Personnel', 'Humans', 'Mexico', 'Surveys and Questionnaires'] | 30,802,177 | [['Z01.107.567.875.760.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['F01.100.150.500', 'N05.300.150.410'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
What proportion of Canadian women will accept an intrauterine contraceptive at the time of second trimester abortion? Baseline data from a randomized controlled trial. | OBJECTIVE: This report details enrolment findings related to a Canadian randomized controlled trial comparing immediate to delayed intrauterine contraception (IUC) placement after a second trimester abortion. We report acceptance of IUC, satisfaction with prior contraception, adherence to the CONSORT criteria, and chal... | ['Abortion, Induced', 'Adult', 'Canada', 'Educational Status', 'Female', 'Humans', 'Income', 'Intrauterine Devices', 'Intrauterine Devices, Copper', 'Intrauterine Devices, Medicated', 'Levonorgestrel', 'Patient Acceptance of Health Care', 'Patient Satisfaction', 'Pregnancy', 'Pregnancy Trimester, Second'] | 24,444,287 | [['E04.520.050'], ['M01.060.116'], ['Z01.107.567.176'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['E07.190.250.510'], ['E07.190.250.510.520.300'], ['E07.190.250.510.520'], ['D04.210.500.668.651.693.762.450'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Health technology assessment in Belgium. | The Belgian healthcare system has a Bismarck-type compulsory health insurance, covering almost the entire population, combined with private provision of care. Providers are public health services, independent pharmacists, independent ambulatory care professionals, and hospitals and geriatric care facilities. Healthcare... | ['Belgium', 'Delivery of Health Care', 'Health Care Reform', 'Hospital Administration', 'National Health Programs', 'Reimbursement Mechanisms', 'Technology Assessment, Biomedical'] | 10,932,412 | [['Z01.542.115'], ['N04.590.374', 'N05.300'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['N03.349.550'], ['N03.219.521.710.305'], ['N03.880', 'N05.715.360.825']] | ['Geographicals [Z]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Self-control concerns and drinking loss of control in general and clinical populations. | In popular conceptions, loss of control over drinking involves a double loss of control, over one's life as well as over one's drinking. A measure of "control worries," concerning the experience of difficulties in controlling one's life, was developed. The relationships between measures of control worries, loss of cont... | ['Adult', 'Alcohol Drinking', 'Alcoholism', 'California', 'Cross-Sectional Studies', 'Female', 'Humans', 'Internal-External Control', 'Male', 'Middle Aged', 'Personality Assessment', 'Substance Abuse Treatment Centers'] | 1,331,615 | [['M01.060.116'], ['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['M01.060.116.630'], ['F04.513'], ['N02.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Commentary - Is the future of "population/public health" in Canada united or divided? Reflections from within the field. | INTRODUCTION: "Are population and public health truly a unified field, or is population health simply attaching itself to public health as a means of gaining credibility?" This commentary was prompted by the above question, which was asked during K. L.'s PhD candidacy exam. In response, K. L. cited recent developments ... | ['Canada', 'Community Health Planning', 'Dissent and Disputes', 'Forecasting', 'Humans', 'Public Health', 'Public Health Administration', 'Social Values', 'Workforce'] | 28,703,704 | [['Z01.107.567.176'], ['N03.349.650.185'], ['F01.829.401.094', 'F02.463.785.373.476'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['N04.452.794'], ['F01.829.873'], ['N04.452.525']] | ['Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Comparative in vitro studies with 4-quinolone antimicrobials. | The minimal inhibitory concentrations (MICs) of nalidixic acid, pipemidic acid, cinoxacin, oxolinic acid, flumequine, pefloxacin, acrosoxacin, amifloxacin, norfloxacin, enoxacin, ofloxacin and ciprofloxacin were determined for a range of clinical isolates. MICs were determined using an agar dilution technique in Muelle... | ['4-Quinolones', 'Anti-Infective Agents', 'Bacteria', 'Cinoxacin', 'Ciprofloxacin', 'Enoxacin', 'Fluoroquinolones', 'Humans', 'Microbial Sensitivity Tests', 'Nalidixic Acid', 'Naphthyridines', 'Norfloxacin', 'Ofloxacin', 'Oxazines', 'Oxolinic Acid', 'Pefloxacin', 'Pipemidic Acid', 'Quinolines', 'Quinolizines', 'Quinolo... | 2,941,259 | [['D03.633.100.810.835.830'], ['D27.505.954.122'], ['B03'], ['D03.066.160', 'D03.633.300.160'], ['D03.633.100.810.835.322.186'], ['D03.633.100.810.835.322.280'], ['D03.633.100.810.835.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D03.633.100.612... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modification and evaluation of the Carba NP test by use of paper strip for simple and rapid detection of carbapenemase-producing Enterobacteriaceae. | Carbapenemase-producing Enterobacteriaceae (CPE) isolates have now emerged worldwide. We therefore modified the phenotypic Carba NP test by use of a filter paper strip for easily and rapidly identifying CPE in routine laboratory. A collection of 56 CPE and carbapenemase-producing Pseudomonas spp. isolates (including 28... | ['Bacterial Proteins', 'Bacteriological Techniques', 'Carbapenems', 'Cilastatin', 'Cilastatin, Imipenem Drug Combination', 'Drug Combinations', 'Enterobacteriaceae', 'Enterobacteriaceae Infections', 'Enzyme Assays', 'Humans', 'Imipenem', 'Phenotype', 'Polymerase Chain Reaction', 'Pseudomonas', 'Reagent Strips', 'beta-L... | 27,263,012 | [['D12.776.097'], ['E01.370.225.875.150', 'E05.200.875.150'], ['D02.065.589.099.124', 'D03.633.100.300.124'], ['D02.455.426.392.368.533.200', 'D10.251.355.325.200'], ['D02.065.589.099.124.300.500.500', 'D02.455.426.392.368.533.200.500', 'D03.633.100.300.124.300.500.500', 'D10.251.355.325.200.500', 'D26.310.356'], ['D26... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple in vivo tyrosine phosphorylation sites in EphB receptors. | Autophosphorylation regulates the function of receptor tyrosine kinases. To dissect the mechanism by which Eph receptors transmit signals, we have developed an approach using matrix-assisted laser desorption-ionization (MALDI) mass spectrometry to map systematically their in vivo tyrosine phosphorylation sites. With th... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Cells, Cultured', 'Chick Embryo', 'Humans', 'Kidney', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Peptide Mapping', 'Phosphorylation', 'Receptor Protein-Tyrosine Kinases', 'Receptor, EphB2', 'Recombinant Proteins', 'Spectrometry, Mass, Matrix-Assisted L... | 10,572,014 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Developing guidelines for thrombolytic therapy. | The development and implementation of guidelines for the use of thrombolytic therapy at a 1000-bed community hospital are described. A thrombolytic therapy committee composed of two physicians, a nurse, and a pharmacist was established to develop the guidelines. The committee outlined goals for the guidelines, develope... | ['Connecticut', 'Drug Utilization', 'Fibrinolytic Agents', 'Formularies, Hospital as Topic', 'Hospital Bed Capacity, 500 and over', 'Humans', 'Pharmacy Service, Hospital', 'Professional Staff Committees', 'United States', 'United States Food and Drug Administration'] | 6,548,871 | [['Z01.107.567.875.550.200'], ['N04.452.706.477'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['L01.178.682.192.836.535.561'], ['N02.278.306.472.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.603', 'N02.421.668.556', 'N04.452.442.452.422.603'], ['N04.452.758.78... | ['Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Utilization of fermented barley extract obtained from a by-product of barley shochu for nisin production. | Fermented barley extract (FBE) obtained from a barley shochu by-product (shochu kasu) and its ethanol fractions were evaluated as a medium and supplement, respectively, for nisin A production by Lactococcus lactis subsp. lactis ATCC 11454. A Brix 2.5 FBE medium supplemented with glucose provided a high level of nisin A... | ['Bioreactors', 'Culture Media', 'Ethanol', 'Fermentation', 'Glucose', 'Hordeum', 'Hydrogen-Ion Concentration', 'Lactates', 'Lactic Acid', 'Lactococcus lactis', 'Nisin', 'Solubility', 'Temperature'] | 19,000,617 | [['E07.115', 'J01.897.120.115'], ['D27.720.470.305', 'E07.206'], ['D02.033.375'], ['G02.111.158.249', 'G03.191.249'], ['D09.947.875.359.448'], ['B01.650.940.800.575.912.250.822.481'], ['G02.300'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['B03.353.750.737.500.400', 'B03.510.400.800.500.400', 'B03.510.550.737.500.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Accountable Care Organizations and Transaction Cost Economics. | Using a Transaction Cost Economics (TCE) approach, this paper explores which organizational forms Accountable Care Organizations (ACOs) may take. A critical question about form is the amount of vertical integration that an ACO may have, a topic central to TCE. We posit that contextual factors outside and inside an ACO ... | ['Accountable Care Organizations', 'Costs and Cost Analysis', 'Decision Making, Organizational', 'Humans', 'Models, Organizational', 'United States'] | 27,009,645 | [['N05.300.380.500'], ['N03.219.151'], ['N04.452.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.670', 'N04.452.534'], ['Z01.107.567.875']] | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Quantitative Flow Ratio Identifies Nonculprit Coronary Lesions Requiring Revascularization in Patients With ST-Segment-Elevation Myocardial Infarction and Multivessel Disease. | BACKGROUND: The nonculprit lesion (NCL) management in ST-segment-elevation myocardial infarction patients with multivessel disease is debated. We sought to assess whether quantitative flow ratio (QFR), a noninvasive tool to identify potentially flow-limiting lesions, may be reliable in this scenario.METHODS AND RESULTS... | ['Aged', 'Blood Flow Velocity', 'Clinical Decision-Making', 'Coronary Angiography', 'Coronary Artery Disease', 'Coronary Circulation', 'Coronary Stenosis', 'Coronary Vessels', 'Female', 'Fractional Flow Reserve, Myocardial', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Middle Aged', 'Myocardial Revascularization', ... | 29,449,325 | [['M01.060.116.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.055'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['G09.330.100.324'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['A... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Relationship between pre-embryo pronuclear morphology (zygote score) and standard day 2 or 3 embryo morphology with regard to assisted reproductive technique outcomes. | OBJECTIVE: To test the hypothesis that pregnancy rates are low if grade Z1 pre-embryos are not available for transfer and to determine if pronuclear morphology is a better predictor of pregnancy than traditional embryo morphology.DESIGN: Prospective clinical study.SETTING: Academic human reproduction laboratory.PATIENT... | ['Adult', 'Blastomeres', 'Embryo Implantation', 'Embryo, Mammalian', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pregnancy', 'Pregnancy Rate', 'Prospective Studies', 'Reproductive Techniques, Assisted', 'Zygote'] | 16,213,842 | [['M01.060.116'], ['A11.872.700.250.130', 'A16.094'], ['G08.686.784.170.104.500'], ['A16.254'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.784.769'], ['E05.318.308.985.775', 'G08.686.705', 'N01.224.935.849', 'N06.850.505.400.975.775', 'N06.850.520.308.985.775'], ['E05.318.372.500.75... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Enhanced percutaneous absorption of formoterol furmarate via pulsed iontophoresis. I. Effect of constant current and constant voltage]. | The effect of iontophoresis on percutaneous absorption of formoterol fumarate (FF) was investigated in vitro with abdominal skin excised from guinea pig. By passive diffusion, the flux at steady state for stripped skin was about 230 times greater than that for intact skin. Therefore, it is suggested that stratum corneu... | ['Animals', 'Bronchodilator Agents', 'Electric Conductivity', 'Ethanolamines', 'Formoterol Fumarate', 'Guinea Pigs', 'In Vitro Techniques', 'Iontophoresis', 'Male', 'Skin', 'Skin Absorption'] | 2,621,565 | [['B01.050'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['G01.358.500.249.277'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['D02.033.100.291.425', 'D02.092.063.291.425'], ['B01.050.150.900.649.313.992.550'], ['E05.481'], ['E02.319.267.650', 'E05.301.300.575'], ['A17.815'], ['G03.015.500.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance. | Oxidative damage caused by reactive oxygen species (ROS) is implicated in many diseases and in aging. Removal of ROS by antioxidant enzymes plays an important part in limiting this damage. For instance, peroxiredoxins (Prx) are conserved, abundant, thioredoxin peroxidase enzymes that function as tumor suppressors. In a... | ['Animals', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'Heat-Shock Response', 'Hydrogen Peroxide', 'Intestinal Mucosa', 'Longevity', 'Oxidation-Reduction', 'Peroxiredoxins', 'Reactive Oxygen Species', 'Tissue Distribution'] | 19,064,914 | [['B01.050'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['G07.775.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['A03.556.124.369', 'A10.615.550.444'], ['G07.345.124.519', 'G07.540'], ['G02.700', 'G03.295.531'], ['D08.811.682.732.850'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolactin (PRL)-like protein J, a novel member of the PRL/growth hormone family, is exclusively expressed in maternal decidua. | A search of a nonmouse, nonhuman, expressed sequence tag database for messenger RNAs in the PRL/GH family has identified a novel rat complementary DNA clone. The encoded protein, designated PRL-like protein J (PLP-J), is predicted to be synthesized as a precursor of 211 amino acids, modified by N-linked glycosylation, ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Chromosome Mapping', 'Chromosomes, Artificial, Yeast', 'DNA, Complementary', 'Decidua', 'Embryo Implantation', 'Female', 'Gene Expression', 'Gestational Age', 'Glycoproteins', 'Glycosylation', 'In Situ Hybridization', 'Intercellular Signaling Peptides and Proteins', ... | 10,537,137 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['A11.284.187.178.200', 'A11.284.187.360.800', 'A19.311.800', 'G05.360.162.178.200', 'G05.360.162.360.800', 'G05.360.337.249.200'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.72... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Changes in CRH and ACTH synthesis during experimental and human septic shock. | CONTEXT: The mechanisms of septic shock-associated adrenal insufficiency remain unclear. This study aimed at investigating the synthesis of corticotropin-releasing hormone (CRH) and vasopressin (AVP) by parvocellular neurons and the antehypophyseal expression of ACTH in human septic shock and in an experimental model o... | ['Adrenocorticotropic Hormone', 'Animals', 'Arginine Vasopressin', 'Corticotropin-Releasing Hormone', 'Disease Models, Animal', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Nitric Oxide Synthase Type II', 'RNA, Messenger', 'Rats', 'Receptors, Vasopressin', 'Shock, Septic'] | 22,073,145 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of a standardized ward round in a prenatal inpatient setting. | OBJECTIVE: To evaluate the impact of incorporating a standardized ward round (SWR) tool including checklists for communication, safety, and efficiency into ward rounds.METHODS: A prospective non-randomized, before-and-after observational study was conducted at a tertiary maternity hospital in Brisbane, Australia, betwe... | ['Australia', 'Checklist', 'Communication', 'Female', 'Hand Hygiene', 'Hospitals, Maternity', 'Humans', 'Inpatients', 'Patient Care Team', 'Patient Satisfaction', "Patients' Rooms", 'Prenatal Care', 'Prospective Studies', 'Surveys and Questionnaires', 'Total Quality Management'] | 28,087,887 | [['Z01.639.100', 'Z01.678.100.373'], ['N05.715.360.300.179'], ['F01.145.209', 'L01.143'], ['E02.547.300', 'N06.850.670.150'], ['N02.278.421.556.366'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['N04.590.715'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625... | ['Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. | Chordin (Chd) is an abundant protein secreted by Spemann organizer tissue during gastrulation. Chd antagonizes signaling by mature bone morphogenetic proteins (BMPs) by blocking binding to their receptors. Recombinant Xenopus Chd binds to BMP-4 with high affinity (KD, 3 x 10(-10) M), binding specifically to BMPs but no... | ['Activins', 'Amino Acid Sequence', 'Animals', 'Binding, Competitive', 'Bone Morphogenetic Protein Receptors', 'Bone Morphogenetic Proteins', 'Carrier Proteins', 'Cells, Cultured', 'Embryonic Induction', 'Extracellular Space', 'Glycoproteins', 'Inhibins', 'Intercellular Signaling Peptides and Proteins', 'Mesoderm', 'Mi... | 8,752,213 | [['D06.472.334.500', 'D06.472.699.009', 'D12.644.548.009', 'D12.776.395.022'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D08.811.913.696.620.682.700.109', 'D12.776.543.750.750.400.049'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Biogeographical patterns in soil bacterial communities across the Arctic region. | The considerable microbial diversity of soils and key role in biogeochemical cycling have led to growing interest in their global distribution and the impact that environmental change might have at the regional level. In the broadest study of Arctic soil bacterial communities to date, we used high-throughput DNA sequen... | ['Arctic Regions', 'Bacteria', 'Biodiversity', 'DNA, Bacterial', 'High-Throughput Nucleotide Sequencing', 'Microbiota', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Soil', 'Soil Microbiology'] | 31,429,869 | [['Z01.208'], ['B03'], ['G16.500.275.157.049', 'N06.230.124.049'], ['D13.444.308.212'], ['E05.393.760.319'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['H01.158.... | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Necrotic enteritis-derived Clostridium perfringens strain with three closely related independently conjugative toxin and antibiotic resistance plasmids. | UNLABELLED: The pathogenesis of avian necrotic enteritis involves NetB, a pore-forming toxin produced by virulent avian isolates of Clostridium perfringens type A. To determine the location and mobility of the netB structural gene, we examined a derivative of the tetracycline-resistant necrotic enteritis strain EHE-NE1... | ['Anti-Bacterial Agents', 'Bacterial Toxins', 'Clostridium perfringens', 'Conjugation, Genetic', 'DNA, Bacterial', 'Drug Resistance, Bacterial', 'Enterocolitis, Necrotizing', 'Enterotoxins', 'Gene Knockout Techniques', 'Gene Transfer, Horizontal', 'Humans', 'Molecular Sequence Data', 'Mutagenesis, Insertional', 'Plasmi... | 21,954,306 | [['D27.505.954.122.085'], ['D23.946.123'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['G05.728.200'], ['D13.444.308.212'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['C06.405.205.596.700', 'C06.405.469.363.700'], ['D23.946.330'], ['E05.393.335.750'], ['G05.728.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A small group of committed people. | This article recounts the author's personal experience with a flawed medication reconciliation system that was improved through her initiative and persistence. The history, function, and value of the nurse navigator role in identifying barriers to care are described. The author advocates for expanding our horizons beyo... | ['Continuity of Patient Care', 'Drug Prescriptions', 'Education, Nursing, Graduate', 'Health Services Accessibility', 'Humans', 'Patient Navigation', 'Systems Theory'] | 23,600,024 | [['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E02.319.307', 'N02.421.668.778.500'], ['I02.358.337.450', 'I02.358.462.565'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.727.407.500'], ['H01.770.808']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Evaluating the impact of vitreomacular adhesion on anti-VEGF therapy for retinal vein occlusion using machine learning. | Vitreomacular adhesion (VMA) represents a prognostic biomarker in the management of exudative macular disease using anti-vascular endothelial growth factor (VEGF) agents. However, manual evaluation of VMA in 3D optical coherence tomography (OCT) is laborious and data on its impact on therapy of retinal vein occlusion (... | ['Angiogenesis Inhibitors', 'Female', 'Humans', 'Machine Learning', 'Macula Lutea', 'Male', 'Retinal Vein Occlusion', 'Tissue Adhesions', 'Tomography, Optical Coherence', 'Treatment Outcome', 'Vascular Endothelial Growth Factor A', 'Visual Acuity'] | 28,592,811 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['A09.371.729.522'], ['C11.768.760', 'C14.907.355.830.925.650', 'C14.907.760'], ['C23.550.355.274.840'], ['E01.370.350.589.249.500', 'E01.370.350.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Antimicrobial activity of quinupristin-dalfopristin (RP 59500, Synercid) tested against over 28,000 recent clinical isolates from 200 medical centers in the United States and Canada. | A total of 200 medical center laboratories in the USA and Canada contributed results of testing quinupristin-dalfopristin, a streptogramin combination (formerly RP 59500 or Synercid), against 28,029 Gram-positive cocci. Standardized tests [disk diffusion, broth microdilution, Etest (AB BIODISK, Solna, Sweden)] were uti... | ['Academic Medical Centers', 'Anti-Bacterial Agents', 'Canada', 'Drug Resistance, Microbial', 'Gram-Positive Bacteria', 'Humans', 'Microbial Sensitivity Tests', 'Species Specificity', 'United States', 'Virginiamycin'] | 9,635,235 | [['N02.278.020'], ['D27.505.954.122.085'], ['Z01.107.567.176'], ['G06.225', 'G07.690.773.984.269'], ['B03.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G16.824'], ['Z01.107.567.875'], ['D04.345.566.802.875', 'D12.644.641.802.875']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Neuroanatomical, immunocytochemical, and physiological studies of the pharyngeal retractor muscle and its putative regulatory neurons playing a role in withdrawal and feeding in the snail, Helix pomatia. | We describe the neurons regulating two separate functions of the pharyngeal retractor muscle (PRM), namely sustained contraction during body withdrawal and rhythmic phasic contractions during feeding, in the snail, Helix pomatia. The distribution of central neurons innervating the PRM is organized into two main units; ... | ['Animals', 'Catecholamines', 'Central Nervous System', 'Dopamine', 'Dose-Response Relationship, Drug', 'Down-Regulation', 'Electric Stimulation', 'FMRFamide', 'Feeding Behavior', 'Ganglia, Invertebrate', 'Helix, Snails', 'Immunohistochemistry', 'Locomotion', 'Membrane Potentials', 'Movement', 'Muscle Contraction', 'Mu... | 15,959,810 | [['B01.050'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['A08.186'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E05.723.402'], ['D12.644.400.235', 'D12.776.631.650.235'], ['F01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Diseases and symptoms as predictors of hospital care in an aged population. A prospective register-based study. | The association between diseases and symptoms and general hospital care was studied in a geographically defined population of 1040 persons aged 65 years or over (90% of the eligible non-institutionalized elderly). In eight years, 25% of the subjects used over 60 hospital bed-days. In age-controlled analyses high use of... | ['Age Factors', 'Aged', 'Female', 'Finland', 'Geriatric Assessment', 'Health Services Research', 'Health Status Indicators', 'Hospitalization', 'Humans', 'Interviews as Topic', 'Linear Models', 'Male', 'Morbidity', 'Predictive Value of Tests', 'Prevalence', 'Prospective Studies', 'Registries', 'Sex Factors'] | 1,496,334 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.542.816.186'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.3... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Extracellular pH modulates the secretion of fibronectin isoforms by human trophoblast. | Differentiation of human trophoblast from the proliferative to the invasive phenotype takes place in a hypoxic and thus likely an acidic microenvironment. During differentiation, the secretion pattern of fibronectin isoforms changes. Therefore, we analysed the relation between extracellular pH, secretion of fibronectin... | ['Blotting, Western', 'Choriocarcinoma', 'Fibronectins', 'Gestational Age', 'Humans', 'Hydrogen-Ion Concentration', 'Immunoenzyme Techniques', 'Protein Isoforms', 'Trophoblasts', 'Tumor Cells, Cultured'] | 11,993,851 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.557.465.955.207', 'C04.557.470.200.025.455', 'C04.850.908.208', 'C13.703.720.949.208'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['G07.345.500.325.235.968', 'G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antisense modulation of the ICAM-1 phenotype of a model human bone marrow stromal cell line. | Efficient stable gene transfer was achieved in a model human bone marrow stromal cell line, KM-102, using both Epstein-Barr virus and BK virus episomal expression vectors. Using this episomal expression system, effective overexpression and inhibition of ICAM-1 expression was achieved in stably transfected KM-102 cells ... | ['BK Virus', 'Bone Marrow Cells', 'Cell Adhesion', 'Cell Line', 'Flow Cytometry', 'Gene Transfer Techniques', 'Genetic Vectors', 'Hematopoietic Stem Cells', 'Herpesvirus 4, Human', 'Humans', 'Intercellular Adhesion Molecule-1', 'Leukemia', 'Models, Biological', 'Oligonucleotides, Antisense', 'Phenotype', 'Plasmids', 'R... | 9,770,366 | [['B04.280.210.700.615.100', 'B04.613.204.670.615.100'], ['A11.148', 'A15.378.316'], ['G04.022'], ['A11.251.210'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['E05.393.350'], ['G05.360.337'], ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liver resection for intrahepatic cholangiocarcinoma. | AIMS AND BACKGROUND: Intrahepatic cholangiocarcinoma (IHCC) is the second most common primary liver cancer, representing 10% of all primary liver malignancies. Despite the increase in its incidence, this tumor remains extremely rare in Western countries and few reports detailing experience with surgical resection have ... | ['Aged', 'Cholangiocarcinoma', 'Female', 'Hepatectomy', 'Humans', 'Incidence', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Retrospective Studies', 'Survival Analysis', 'Treatment Outcome'] | 16,457,147 | [['M01.060.116.100'], ['C04.557.470.200.025.450'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E01.789.625'], ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Carer satisfaction with end-of-life care in Powys, Wales: a cross-sectional survey. | A cross-sectional postal survey of bereaved carers was conducted in order to examine levels of satisfaction with services provided for people in their last year of life in the rural county of Powys, Wales, UK. A self-complete questionnaire, using a modified version of the Views of Informal Carers - Evaluation of Servic... | ['Aged', 'Caregivers', 'Consumer Behavior', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Neoplasms', 'Rural Health Services', 'Surveys and Questionnaires', 'Terminal Care', 'Wales'] | 14,675,364 | [['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F01.145.236'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['N02.421.816'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['E02.760.905... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity. | Recent evidence indicates the presence of alternative pathways for microRNA (miRNA) and short hairpin (shRNA) processing. Specifically, some of these molecules are refractory to Dicer-mediated processing, which allows alternative processing routes via the Ago2 endonuclease. The resulting RNA molecules differ in size an... | ['Argonaute Proteins', 'Base Pairing', 'Base Sequence', 'Binding Sites', 'DEAD-box RNA Helicases', 'Gene Knockdown Techniques', 'HCT116 Cells', 'HEK293 Cells', 'Humans', 'Nucleic Acid Conformation', 'Protein Binding', 'RNA Processing, Post-Transcriptional', 'RNA, Small Interfering', 'Ribonuclease III'] | 25,035,295 | [['D08.811.277.352.355.350.810.500', 'D08.811.277.352.700.350.810.500', 'D12.776.157.725.500.906.500', 'D12.776.664.962.500.906.500'], ['G02.111.570.820.486.100', 'G02.111.611.500', 'G05.360.580.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D08.811.913.696.445.735.720.249'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The juggling act: Do student nurses who care for dependants need an adapted course? An applied policy research study. | BACKGROUND: In line with many countries worldwide, the Department of Health mandate to Health Education England seeks to promote the diversity of applicants by widening participation in nurse education. A number of studies have explored the experience of non-traditional students undertaking nursing courses.OBJECTIVES: ... | ['Adolescent', 'Adult', 'Attitude of Health Personnel', 'Child', 'Child, Preschool', 'Curriculum', 'Education, Nursing, Baccalaureate', 'England', 'Family', 'Female', 'Focus Groups', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Qualitative Research', 'Students, Nursing', 'Time Factors'] | 26,169,286 | [['M01.060.057'], ['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['M01.060.406'], ['M01.060.406.448'], ['I02.158'], ['I02.358.462.316'], ['Z01.542.363.300'], ['F01.829.263', 'I01.880.853.150'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.31... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Phenomena ... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Plasma cathepsin L: a prognostic marker for pancreatic cancer. | AIM: To assess the prognostic significance of cathepsin L, a cysteine protease that degrades the peri-tumoral tissue, in patients with pancreatic cancer.METHODS: Plasma samples from 127 pancreatic cancer patients were analyzed for cathepsin L levels by ELISA. Out of these patients, 25 underwent surgery and their paraff... | ['Aged', 'Area Under Curve', 'Biomarkers, Tumor', 'CA-19-9 Antigen', 'Case-Control Studies', 'Cathepsin L', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Pancreatic Neoplasms', 'Predictive Value of Tests', 'Prog... | 25,516,668 | [['M01.060.116.100'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101.140'], ['D23.050.285.050.119', 'D23.050.301.290.544.119', 'D23.050.550.325.119', 'D23.050.705.230.544.119', 'D23.101.140.075.119'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Thermococcus celericrescens sp. nov., a fast-growing and cell-fusing hyperthermophilic archaeon from a deep-sea hydrothermal vent. | A fast-growing and cell-fusing hyperthermophilic archaeon was isolated from a hydrothermal vent at Suiyo Seamount, Izu-Bonin Arc, Western Pacific Ocean. Strain TS2(T) is an irregular, motile coccus that is generally 0.7-1.5 microm in diameter and possesses a polar tuft of flagella. In the mid-exponential phase of growt... | ['DNA, Archaeal', 'Genes, rRNA', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Seawater', 'Temperature', 'Thermococcus'] | 17,329,765 | [['D13.444.308.180'], ['G05.360.340.024.340.645.750'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['G16.500.275.725.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['B02.200.825.800.800']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Autism spectrum disorders and motor skills: the effect on socialization as measured by the Baby And Infant Screen For Children with aUtIsm Traits (BISCUIT). | PURPOSE: To examine the effects of ASD diagnosis and motor skills on socialization in young children.METHODS: Two samples were used: gross motor skills sample (n = 408) and fine motor skills sample (n = 402). The Battelle Developmental Inventory-Second Edition assessed motor skills, while the Baby and Infant Screen for... | ['Child Behavior', 'Child Development', 'Child Development Disorders, Pervasive', 'Child, Preschool', 'Early Diagnosis', 'Female', 'Humans', 'Infant', 'Infant Behavior', 'Male', 'Motor Skills', 'Psychiatric Status Rating Scales', 'Socialization'] | 21,870,953 | [['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['F03.625.164'], ['M01.060.406.448'], ['E01.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.145.179.500'], ['F02.808.260'], ['F04.711.513.653'], ['I01.880.853.934']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports. | BACKGROUND: The process of generating 'signals' of possible unrecognized hazards from spontaneous adverse drug reaction reporting data has been likened to looking for a needle in a haystack. However, statistical approaches to the data have been under-utilised.METHODS: Using the UK Yellow Card database, we have develope... | ['Adverse Drug Reaction Reporting Systems', 'Data Interpretation, Statistical', 'Databases, Factual', 'Software'] | 11,828,828 | [['E05.337.800.120', 'N02.421.668.320.120'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Uroporphyria induced by 5-aminolaevulinic acid alone in Ahrd SWR mice. | In mice, depression of hepatic uroporphyrinogen decarboxylase (UROD) leading to porphyrin accumulation (uroporphyria) occurs with chlorinated ligands of the aryl hydrocarbon (AH) receptor especially after iron overload. However, in the absence of chlorinated ligands, iron itself will eventually cause uroporphyria, but ... | ['Aminolevulinic Acid', 'Animals', 'Cytochrome P-450 Enzyme System', 'Genotype', 'Iron Overload', 'Liver', 'Male', 'Mice', 'Mice, Inbred DBA', 'Porphyrias', 'Receptors, Aryl Hydrocarbon', 'Species Specificity', 'Uroporphyrinogen Decarboxylase'] | 8,937,451 | [['D02.241.755.547.276', 'D12.125.262'], ['B01.050'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G05.380'], ['C18.452.565.500'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.500', 'B01.050.150.900.649.313.992.635.505.500.400.500'], ['C18.452.811'], ['D12.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation between the functional assay for activated protein C resistance and factor V Leiden in the neonate. | A factor V506 Arg-Gln mutation is the most common inherited cause of thrombophilia in adults. To date, there are no data regarding the detection of this mutation in neonatal blood or the relationship of this dysfunctional factor V to neonatal thrombosis. This study compared a modified activated protein C resistance fun... | ['Amino Acid Substitution', 'Arginine', 'Drug Resistance', 'Factor V', 'Humans', 'Infant, Newborn', 'Mutation', 'Partial Thromboplastin Time', 'Protein C', 'Sensitivity and Specificity'] | 9,396,556 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G07.690.773.984'], ['D12.776.124.125.300', 'D12.776.811.272', 'D23.119.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G05.365.590'], ['E01.370.225.625.115.600', 'E05.200.625.115.600', 'G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of MSH2 deficiency on spontaneous and radiation-induced mutation rates in the mouse germline. | Mutation rates at two expanded simple tandem repeat (ESTR) loci were studied in the germline of mismatch repair deficient Msh2 knock-out mice. Spontaneous mutation rates in homozygous Msh2(-/-) males were significantly higher than those in isogenic wild-type (Msh2(+/+)) and heterozygous (Msh2(+/-)) mice. In contrast, t... | ['Animals', 'Female', 'Germ-Line Mutation', 'Heterozygote', 'Homozygote', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'MutS Homolog 2 Protein', 'Radiation Tolerance', 'Radiation, Ionizing', 'Tandem Repeat Sequences'] | 17,331,550 | [['B01.050'], ['G05.365.590.350'], ['G05.380.383'], ['G05.380.554'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Congenital cervical thymic cyst]. | Congenital cervical thymic cysts are a very rare cause of tumor of the neck in children. They can exceptionally induce a laryngeal compression. Actual identification of the tumor may sometimes be made only after surgery and histologic examination. Evolution is benign. Their existence seems to be related to the persiste... | ['Child', 'Humans', 'Male', 'Mediastinal Cyst', 'Neck', 'Time Factors'] | 4,083,981 | [['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.182.444', 'C08.846.187.145'], ['A01.598'], ['G01.910.857']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dietary acculturation and diet quality of hypertensive Korean Americans. | AIM: This paper is a report of a study to describe the dietary acculturation of hypertensive and normotensive Korean Americans and native Koreans by comparing dietary pattern and diet quality.BACKGROUND: Dietary acculturation is a major factor that influences the risks for cardiovascular disease in immigrants. Nurses p... | ['Acculturation', 'Adult', 'Asian Americans', 'Case-Control Studies', 'Chicago', 'Cross-Cultural Comparison', 'Diet', 'Diet Surveys', 'Empirical Research', 'Feeding Behavior', 'Female', 'Humans', 'Hypertension', 'Korea', 'Male', 'Middle Aged'] | 17,442,024 | [['I01.076.201.450.050', 'I01.880.853.100.079'], ['M01.060.116'], ['M01.686.508.200.100', 'M01.686.754.225'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.107.567.875.350.350.200', 'Z01.107.567.875.510.350.200', 'Z01.433.305'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['G0... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseas... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Prevalence and associated risk factors of violence against conflict-affected female adolescents: a multi-country, cross-sectional study. | BACKGROUND: Over half of displaced civilians in humanitarian emergencies are children, and these settings pose unique threats to children's safety with long-lasting consequences. Our study broadens the limited evidence on violence against adolescent girls in emergencies by estimating prevalence and predictors of violen... | ['Adolescent', 'Armed Conflicts', 'Cross-Sectional Studies', 'Democratic Republic of the Congo', 'Ethiopia', 'Female', 'Humans', 'Prevalence', 'Refugees', 'Risk Factors', 'Surveys and Questionnaires', 'Violence', 'Young Adult'] | 28,607,672 | [['M01.060.057'], ['I01.880.735.950.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.058.290.100.220'], ['Z01.058.290.120.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Polymorphism of MHC-DPB1 gene exon 2 in rhesus macaques (Macaca mulatta)]. | Rhesus macaque (Macaca mulatta) has long been used as an experimental model animal for biomedical research and was under the key state protection (class II) from Chinese government. In order to facilitate the use of Chinese rhesus macaques in biomedical research and their protection based on better understanding of the... | ['Amino Acid Sequence', 'Animals', 'Exons', 'Gene Frequency', 'HLA-DP Antigens', 'HLA-DP beta-Chains', 'Macaca fascicularis', 'Macaca mulatta', 'Molecular Sequence Data', 'Phylogeny', 'Polymorphism, Genetic'] | 20,566,463 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G05.360.340.024.340.137.232'], ['G05.330'], ['D12.776.395.550.509.400.420', 'D12.776.543.550.440.400.420', 'D23.050.301.500.400.400.420', 'D23.050.301.500.450.400.420', 'D23.050.705.552.410.400.420', 'D23.050.705.552.450.400.420'], ['D12.776.395.550.509.400.42... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Concerns in child welfare, developmental disabilities, and HIV infection. | The special concerns of the child welfare community regarding pediatric HIV infection were described. These include appropriate use of foster care, preparation and commitment of personnel, and assurance of access to necessary services. There are both contrasts and common interests in work with this population between c... | ['Acquired Immunodeficiency Syndrome', 'Attitude of Health Personnel', 'Child', 'Child Health Services', 'Child Welfare', 'Delivery of Health Care', 'Developmental Disabilities', 'Foster Home Care', 'HIV Infections', 'Humans', 'Quality of Health Care', 'United States', 'Workforce'] | 2,479,811 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['F01.100.050', 'N05.300.100'], ['M01.060.406'], ['N02.421.143.130'], ['I01.880.787.293'], ['N04.590.374', 'N05.300'], ['F03.625.421'], ['E02.760.352', ... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies. | This report describes the proceedings of the BfR-RIVM workshop on validation of alternative methods which was held 23 and 24 March 2017 in Berlin, Germany. Stakeholders from governmental agencies, regulatory authorities, universities, industry and the OECD were invited to discuss current problems concerning the regulat... | ['Animal Testing Alternatives', 'Animals', 'Government Agencies', 'Humans', 'Reproducibility of Results', 'Risk Assessment', 'Toxicity Tests'] | 29,501,630 | [['E05.017.080.100'], ['B01.050'], ['I01.409.418', 'N03.540.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
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