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US spending on complementary and alternative medicine during 2002-08 plateaued, suggesting role in reformed health system. | Complementary and alternative medicine services in the United States are an approximately $9 billion market each year, equal to 3 percent of national ambulatory health care expenditures. Unlike conventional allopathic health care, complementary and alternative medicine is primarily paid for out of pocket, although some... | ['Adult', 'Complementary Therapies', 'Cost Savings', 'Female', 'Health Care Reform', 'Health Expenditures', 'Health Services Research', 'Humans', 'Male', 'Manipulation, Chiropractic', 'Referral and Consultation', 'United States'] | 23,297,270 | [['M01.060.116'], ['E02.190'], ['N03.219.151.160.200'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['N03.219.151.450', 'N05.300.385'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Population variation in second metacarpal sexual size dimorphism. | This paper contrasts levels of sexual size dimorphism in second metacarpal osteometric and geometric morphology in two bioculturally distinctive populations: 19th century Euro-Canadian settlers, and proto/historic central Canadian Inuit. Significant within-group sexual size dimorphism is found for all variables, though... | ['Anthropology, Physical', 'Canada', 'Female', 'Humans', 'Inuits', 'Male', 'Metacarpus', 'Sex Characteristics'] | 12,124,917 | [['I01.076.368'], ['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600.375.500', 'M01.686.508.150.675', 'M01.686.754.254.500.500'], ['A01.378.800.667.572'], ['G08.686.815']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Long-term panmixia in a cosmopolitan Indo-Pacific coral reef fish and a nebulous genetic boundary with its broadly sympatric sister species. | Phylogeographical studies have shown that some shallow-water marine organisms, such as certain coral reef fishes, lack spatial population structure at oceanic scales, despite vast distances of pelagic habitat between reefs and other dispersal barriers. However, whether these dispersive widespread taxa constitute long-t... | ['Animals', 'Bayes Theorem', 'Cell Nucleus', 'DNA, Mitochondrial', 'Evolution, Molecular', 'Gene Flow', 'Genetic Loci', 'Genetic Markers', 'Genetic Variation', 'Genetics, Population', 'Introns', 'Mitochondria', 'Perciformes', 'Phylogeography', 'Population Density', 'Reproductive Isolation', 'Sympatry'] | 23,305,496 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D13.444.308.283.225'], ['G05.045.250', 'G16.075.250'], ['G05.330.159'], ['G05.360.340.024.380'], ['D23.101.387', 'G05.695.450'], ['G05.365'], ['H01.158.273.343.335'], ['G05.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Lung proliferative and clearance responses to inhaled para-aramid RFP in exposed hamsters and rats: comparisons with chrysotile asbestos fibers. | This study compared pulmonary effects of para-aramid respirable-sized, fiber-shaped particles (RFP) (p-aramid fibrils) and chrysotile asbestos fiber exposures in rats. Additional p-aramid inhalation studies were conducted in hamsters to compare species responses. The hamster results are preliminary. The parameters stud... | ['Administration, Inhalation', 'Animals', 'Antimetabolites', 'Asbestos, Serpentine', 'Biodegradation, Environmental', 'Bromodeoxyuridine', 'Carcinogens', 'Cell Division', 'Cricetinae', 'Lung', 'Male', 'Mesocricetus', 'Polymers', 'Rats', 'Rats, Inbred Strains'] | 9,400,727 | [['E02.319.267.050'], ['B01.050'], ['D27.505.519.186', 'D27.888.569.042'], ['D01.524.500.050', 'D01.578.725.050.075', 'D01.578.725.500.050', 'D01.837.725.700.760.070.110', 'D01.837.725.700.760.535.400'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Co-exposure with titanium dioxide nanoparticles exacerbates MCLR-induced brain injury in zebrafish. | Owing to the eutrophication in freshwater and industrial emissions, the detected concentrations of MCLR and nano-TiO2 in nature water increase year by year. The purpose of this study was to evaluate the joint effect of microcystin-LR (MCLR) and titanium dioxide nanoparticles (nano-TiO2) on the zebrafish brain and to in... | ['Animals', 'Antioxidants', 'Brain Injuries', 'Fresh Water', 'Glutathione', 'Lipid Peroxidation', 'Marine Toxins', 'Metal Nanoparticles', 'Microcystins', 'Oxidative Stress', 'Superoxide Dismutase', 'Titanium', 'Water Pollutants, Chemical', 'Zebrafish'] | 31,374,495 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G16.500.275.280', 'N06.230.232'], ['D12.644.456.448'], ['G02.111.515', 'G03.295.531.587'], ['D23.946.580'], ['J01.637.512.600.500'], ['D04.345.566.447', 'D12.644.641.447', 'D23.946.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Time perspective, socioeconomic status, and psychological distress in chronic pain patients. | Time perspective (TP) is a fundamental dimension of the psychological construction of time. It refers to a subjective experience and can be defined as the relationship that individuals and groups have with the present, past, and future. Studies have shown that it is interesting to take into account TP in the field of h... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Chronic Pain', 'Female', 'Humans', 'Male', 'Middle Aged', 'Poverty', 'Regression Analysis', 'Social Class', 'Stress, Psychological', 'Surveys and Questionnaires', 'Time Perception', 'Young Adult'] | 26,153,853 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['C23.888.592.612.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Explaining the convergence of male and female smoking prevalence in Australia. | OBJECTIVE: To examine changes in age of tobacco experimentation and progression to daily smoking in men and women between birth cohorts that differ in exposure to public health programmes that aim to discourage smoking.DESIGN: Analysis of national cross-sectional household surveys of smoking patterns, conducted in Aust... | ['Adult', 'Age Factors', 'Aged', 'Australia', 'Epidemiologic Methods', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sex Factors', 'Smoking'] | 18,190,667 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.805']] | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Molecular characterization and expression analysis of soluble trehalase gene in Aphis glycines, a migratory pest of soybean. | In insects, the enzyme trehalase plays a crucial role in energy metabolism, chitin synthesis and possibly during plant-insect interactions. We have characterized a soluble trehalase gene (Tre-1) from cDNA of Aphis glycines, a serious migratory pest of soybean. The full-length cDNA of Tre-1 in A. glycines (AyTre-1) was ... | ['Animals', 'Aphids', 'Cluster Analysis', 'Computational Biology', 'DNA, Complementary', 'Gastrointestinal Tract', 'Gene Expression Profiling', 'Larva', 'Models, Genetic', 'Open Reading Frames', 'Phylogeny', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Soybeans', 'Trehalase'] | 23,445,549 | [['B01.050'], ['B01.050.500.131.617.412.165'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['A03.556'], ['E05.393.332'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E05.599.395.397... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Short-Term Outcome of Ischemic Stroke Patients With Systemic Malignancy. | Background and Purpose- Recent guidelines have suggested the potential benefit of intravenous thrombolysis in stroke patients with systemic malignancy who have a reasonable life expectancy of >6 months. However, it is difficult to determine which patients with cancer will have a life expectancy of >6 months. Therefore,... | ['Aged', 'Aged, 80 and over', 'Brain Ischemia', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasms', 'Risk Factors', 'Stroke', 'Thrombolytic Therapy', 'Time Factors'] | 30,626,288 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.150', 'C14.907.253.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['C04'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A claudin-9-based ion permeability barrier is essential for hearing. | Hereditary hearing loss is one of the most common birth defects, yet the majority of genes required for audition is thought to remain unidentified. Ethylnitrosourea (ENU)-mutagenesis has been a valuable approach for generating new animal models of deafness and discovering previously unrecognized gene functions. Here we... | ['Animals', 'Biological Transport', 'Claudins', 'Cochlea', 'Disease Models, Animal', 'Female', 'Hair Cells, Auditory', 'Hearing Loss', 'Humans', 'Ions', 'Male', 'Membrane Proteins', 'Mice', 'Mice, Inbred A', 'Mice, Transgenic', 'Mutagenesis', 'Permeability', 'Tight Junctions'] | 19,696,885 | [['B01.050'], ['G03.143'], ['D12.776.543.940.200'], ['A09.246.300.246'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A08.675.650.250', 'A08.675.650.915.750.600.350', 'A08.800.950.750.600.350', 'A09.246.300.246.577.325', 'A11.671.650.250', 'A11.671.650.915.750.600.350'], ['C09.218.458.341', 'C10.597.751.418.341', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correctors enhance maturation of DeltaF508 CFTR by promoting interactions between the two halves of the molecule. | Deletion of Phe508 in cystic fibrosis transmembrane conductance regulator (DeltaF508 CFTR) causes cystic fibrosis. CFTR consists of two homologous halves with each containing a nucleotide-binding domain (NBD) and a transmembrane domain (TMD). DeltaF508 CFTR appears to be trapped in an incompletely folded state. Small m... | ['Codon', 'Cystic Fibrosis', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'DNA, Complementary', 'Glycosylation', 'Humans', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Protein Conformation', 'Protein Folding', 'Sequence Deletion'] | 19,761,259 | [['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500', 'D12.776.543.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Local application of anti-cancer drugs for the treatment of malignant pleural and pericardial effusion]. | Pleural effusion is a common complication in patients with malignant neoplasm. A randomized controlled study of intrapleural instillation of Adriamycin (control group, 30 patients) and Adriamycin Nocardia rubra cell wall skeleton (N-CWS group, 26 patients) with tube thoracostomy was performed in 55 patients with malign... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'BCG Vaccine', 'Bleomycin', 'Carcinoma, Squamous Cell', 'Cell Wall', 'Doxorubicin', 'Drainage', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Mitomycin', 'Mitomycins', 'Nimustine', 'Nitrosourea Compounds', 'Nocardia', ... | 6,206,796 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D20.215.894.135.825.100'], ['D09.400.420.110', 'D12.644.233.110'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.284.183'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.17... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
NLR surveillance of essential SEC-9 SNARE proteins induces programmed cell death upon allorecognition in filamentous fungi. | In plants and metazoans, intracellular receptors that belong to the NOD-like receptor (NLR) family are major contributors to innate immunity. Filamentous fungal genomes contain large repertoires of genes encoding for proteins with similar architecture to plant and animal NLRs with mostly unknown function. Here, we iden... | ['Amino Acid Sequence', 'Apoptosis', 'Fungal Proteins', 'Molecular Sequence Data', 'NLR Proteins', 'Neurospora crassa', 'Podospora', 'Protein Binding', 'Protein Domains', 'SNARE Proteins', 'Sequence Alignment'] | 29,463,729 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G04.146.954.035'], ['D12.776.354'], ['L01.453.245.667'], ['D12.644.360.539'], ['B01.300.107.800.629.564'], ['B01.300.107.800.700'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['D12.776.543.512.249', 'D12.776.543.990.775'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The ecology of Haemonchus contortus in a winter rainfall climate in Australia: the survival of infective larvae on pasture. | At sites near Albany, on the south coast of Western Australia, sheep faecal pellets containing either eggs or infective larvae (L3) of Haemonchus contortus were deposited onto natural pasture plots at intervals over 3 years. Faecal and pasture samples were collected periodically and processed to detect L3. On annual pa... | ['Animals', 'Feces', 'Haemonchus', 'Larva', 'Rain', 'Seasons', 'Sheep', 'Temperature', 'Western Australia'] | 8,447,071 | [['B01.050'], ['A12.459'], ['B01.050.500.500.294.400.968.746.410'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Discovery and SARs of 5-Chloro-N | Cyclin-dependent kinases (CDKs) are promising therapeutic targets for cancer therapy. Herein, we describe our efforts toward the discovery of a series of 5-chloro-N4-phenyl-N2-(pyridin-2-yl)pyrimidine-2,4-diamine derivatives as dual CDK6 and 9 inhibitors. Intensive structural modifications lead to the identification of... | ['Administration, Oral', 'Animals', 'Antineoplastic Agents', 'Apoptosis', 'Catalytic Domain', 'Cell Line, Tumor', 'Cell Proliferation', 'Cyclin-Dependent Kinase 6', 'Cyclin-Dependent Kinase 9', 'Humans', 'Male', 'Mice, Inbred BALB C', 'Molecular Docking Simulation', 'Molecular Structure', 'Neoplasms', 'Protein Binding'... | 32,129,996 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.913.696.620.682.700.646.500.937', 'D12.644.360.250.515', 'D12.776.167.200.515', 'D12.776.476.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The radical revolution of radiology. | The radiologic segment of the health care industry has grown dramatically in size and functions. The focus on cancer and heart disease has made it a key core functional area for health systems and physician groups. Aggressive growth plans are based on key strategies, high demand services, and other critical success fac... | ['Health Care Sector', 'Organizational Innovation', 'Planning Techniques', 'Practice Management, Medical', 'Radiology', 'United States'] | 11,009,737 | [['J01.576.489', 'N03.219.650'], ['N04.452.610'], ['N04.452.718'], ['N04.452.758.708.450'], ['H02.403.740'], ['Z01.107.567.875']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Direct and indirect effects of glomalin, mycorrhizal hyphae, and roots on aggregate stability in rhizosphere of trifoliate orange. | To test direct and indirect effects of glomalin, mycorrhizal hyphae, and roots on aggregate stability, perspex pots separated by 37-ìm nylon mesh in the middle were used to form root-free hyphae and root/hyphae chambers, where trifoliate orange (Poncirus trifoliata) seedlings were colonized by Funneliformis mosseae or ... | ['Fungal Proteins', 'Glomeromycota', 'Glycoproteins', 'Hyphae', 'Mycorrhizae', 'Plant Roots', 'Poncirus', 'Rhizosphere', 'Seedlings'] | 25,059,396 | [['D12.776.354'], ['B01.300.320'], ['D09.400.430', 'D12.776.395'], ['A19.687.400'], ['A18.400.525', 'A19.690', 'B01.300.655', 'B05.550'], ['A18.400'], ['B01.650.940.800.575.912.250.875.755'], ['G16.500.275.157.625', 'G16.500.853', 'N06.230.124.437'], ['A18.550', 'B01.650.819']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dysregulated phosphatidylinositol signaling promotes endoplasmic-reticulum-stress-mediated intestinal mucosal injury and inflammation in zebrafish. | Dysregulated phosphatidylinositol (PI) signaling has been implicated in human gastrointestinal (GI) malignancies and inflammatory states, underlining the need to study pathophysiological roles of PI in an in vivo genetic model. Here, we study the significance of PI in GI pathophysiology using the zebrafish mutant cdipt... | ['Alleles', 'Animals', 'Animals, Genetically Modified', 'Apoptosis', 'Cell Proliferation', 'Disease Models, Animal', 'Endoplasmic Reticulum', 'Endoplasmic Reticulum Stress', 'Gene Expression Regulation', 'Genotype', 'Glycosylation', 'Humans', 'Inflammation', 'Intestinal Mucosa', 'Leukocytes', 'Mitochondria', 'Mutation'... | 24,135,483 | [['G05.360.340.024.340.030'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.284.430.214.190.875.248'], ['G04.434'], ['G05.308'], ['G05.380'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence and associated factors for asthma in Brazilian and Japanese schoolchildren living in the city of S?o Paulo, Brazil. | OBJECTIVES: Ethnic background interferes on the prevalence of asthma among schoolchildren (4 to 9 years old, SC) born and living in S?o Paulo, Brazil.METHODS: International Study of Asthma and Allergy in Childhood (ISAAC)'s written standard and complementary questionnaires were applied to SC (similar socioeconomic stat... | ['Age Factors', 'Asian Continental Ancestry Group', 'Asthma', 'Brazil', 'Child', 'Child, Preschool', 'Cultural Characteristics', 'Environment', 'Female', 'Humans', 'Japan', 'Male', 'Prevalence', 'Risk Factors', 'Surveys and Questionnaires', 'Urban Health'] | 27,425,168 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.686.508.200'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Nutritional covariates of dietary calcium in elderly Japanese women: results of a study using the duplicate portion sampling method. | OBJECTIVES: The purposes of this study were to determine the intake of nutrients related to bone health, including calcium (Ca), phosphorus (P), sodium (Na), potassium (K), protein, and vitamin D, in elderly Japanese women and to examine possible intercorrelations between Ca intake and other nutrients.METHODS: Fifty-th... | ['Aged', 'Aging', 'Animals', 'Body Height', 'Body Mass Index', 'Body Weight', 'Bone and Bones', 'Calcium, Dietary', 'Dietary Proteins', 'Female', 'Humans', 'Japan', 'Middle Aged', 'Milk', 'Nutritional Status', 'Phosphorus, Dietary', 'Potassium, Dietary', 'Rural Population', 'Sodium, Dietary', 'Vitamin D'] | 14,624,939 | [['M01.060.116.100'], ['G07.345.124'], ['B01.050'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
The efficacy of chemoprophylaxis against malaria with chloroquine plus proguanil, mefloquine, and atovaquone plus proguanil in travelers from Denmark. | BACKGROUND: The risk of malaria infection in travelers is seldom known in detail and neither is the efficacy of different prophylactic regimens, due to a lack of controlled trials. Surveillance of malaria diagnosed after return can provide data on risk and efficacy.METHODS: An open case-control study was initiated. Imp... | ['Africa', 'Antimalarials', 'Asia', 'Atovaquone', 'Case-Control Studies', 'Chloroquine', 'Denmark', 'Disease Outbreaks', 'Drug Therapy, Combination', 'Humans', 'Incidence', 'Malaria', 'Malaria, Falciparum', 'Malaria, Vivax', 'Mefloquine', 'Naphthoquinones', 'Patient Compliance', 'Proguanil', 'Travel', 'Treatment Outcom... | 12,757,688 | [['Z01.058'], ['D27.505.954.122.250.100.085'], ['Z01.252'], ['D02.806.550.312', 'D04.615.638.721.186'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D03.633.100.810.050.180'], ['Z01.542.816.124'], ['N06.850.290'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Incorrect evaluation of the frequency of malnutrition and of its screening in hospitalized children by health care professionals. | RATIONALE, AIMS AND OBJECTIVES: Malnutrition screening is essential to detect and to treat patients with stunting or wasting. The aim was to evaluate the subjective perception of frequency and assessment of malnutrition by health care professionals.RESEARCH METHODS AND PROCEDURES: In a paediatric university hospital, a... | ['Adolescent', 'Body Height', 'Body Weight', 'Child', 'Child Nutrition Disorders', 'Child, Hospitalized', 'Child, Preschool', 'Cross-Sectional Studies', 'Diagnostic Errors', 'Health Personnel', 'Hospitals, Pediatric', 'Hospitals, University', 'Humans', 'Infant', 'Infant, Newborn', 'Mass Screening', 'Prevalence'] | 26,202,860 | [['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['C18.654.180'], ['M01.643.259'], ['M01.060.406.448'], ['E05.318.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endogenous and exogenous hydrogen sulfide facilitates T-type calcium channel currents in Cav3.2-expressing HEK293 cells. | Hydrogen sulfide (H2S), a gasotransmitter, is formed from l-cysteine by multiple enzymes including cystathionine-ã-lyase (CSE). We have shown that an H2S donor, NaHS, causes hyperalgesia in rodents, an effect inhibited by knockdown of Cav3.2 T-type Ca(2+) channels (T-channels), and that NaHS facilitates T-channel-depen... | ['Alkynes', 'Animals', 'Blotting, Western', 'Calcium', 'Calcium Channels, T-Type', 'Cell Line, Tumor', 'Cystathionine gamma-Lyase', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation, Enzymologic', 'Glycine', 'HEK293 Cells', 'Humans', 'Hydrogen Sulfide', 'Male', 'Membrane Potentials', 'Mice', 'Pain Thresho... | 24,508,802 | [['D02.455.326.397'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150.720', 'D12.776.543.550.450.150.720', 'D12.776.543.585.400.150.720'], ['A11.251.210.190', 'A11.251.860.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relationship of personality traits and entrepreneurship tendencies with career adaptability of nursing students. | PURPOSE: This study was performed to reveal the relationship of nursing students' personality traits and entrepreneurship tendency with career adaptability.METHOD: This descriptive and correlational study's sample consisted of the junior and senior students in the nursing faculty of a state university in Istanbul (n = ... | ['Adult', 'Career Choice', 'Cross-Sectional Studies', 'Emotions', 'Entrepreneurship', 'Female', 'Humans', 'Male', 'Personality', 'Students, Nursing', 'Surveys and Questionnaires', 'Young Adult'] | 31,102,796 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.470'], ['J01.219.375', 'N04.452.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752'], ['M01.848.769.685'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.98... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Determination of trace silver by solid substrate-room temperature phosphorescence quenching method based on double catalytic system of meta-nitrophenyfluorone-polyoxyethylene-chromium-potassium bromate-beta-cyclodextrin. | A new solid substrate-room temperature phosphorescence (SS-RTP) quenching method for the determination of trace silver has been established. It is based on the fact that when using Mg(2+) as ion perturber and beta-CD as surfactant, the system of meta-nitrophenyfluorone (R)-polyoxyethylene-Cr(III) can emit strong and st... | ['Catalysis', 'Coloring Agents', 'Cyclodextrins', 'Luminescent Measurements', 'Silver', 'Spectrometry, Fluorescence', 'Temperature'] | 16,356,765 | [['G02.130'], ['D27.720.233'], ['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['E05.196.712.516'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Development of near-field optic/atomic force microscope for biological materials in aqueous solutions. | This paper reports improvements of optical fiber cantilevers and the scanning near-field optical microscopy imaging of biological materials in liquid. In our scanning near-field optical/atomic-force microscope (SNOAM), the scanning of an optical fiber cantilever over the specimen was controlled by dynamic mode AFM to r... | ['Animals', 'Cells, Cultured', 'Fibroblasts', 'Kidney', 'Microscopy, Atomic Force', 'Rats'] | 8,677,524 | [['B01.050'], ['A11.251'], ['A11.329.228'], ['A05.810.453'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomical evidence supporting the potential for modulation by multiple neurotrophins in the majority of adult lumbar sensory neurons. | Neurotrophins exert effects on sensory neurons through receptor tyrosine kinases (trks) and a common neurotrophin receptor (p75). Quantitative in situ hybridization studies were performed on serial sections to identify neurons expressing single or multiple neurotrophin trk receptor mRNA(s) in adult lumbar dorsal root g... | ['Animals', 'Base Sequence', 'Ganglia, Spinal', 'Gene Expression', 'In Situ Hybridization', 'Lumbosacral Region', 'Male', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Neurons, Afferent', 'Phenotype', 'Protein Isoforms', 'RNA, Messenger', 'Rats', 'Rats, Wistar', 'Receptor, Nerve Growth Factor', 'Receptor, trkA',... | 10,524,342 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.297'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['A01.923.176.519'], ['L01.453... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An individualized approach to surgical reconstruction for lateral polydactyly of the foot with an emphasis on collateral ligament reconstruction. | BACKGROUND: Most previous studies concerning the treatment of polydactyly of the foot have focused on surgical techniques for aesthetic improvement rather than functional alignment of the reconstructed toe. The purpose of this study was to present the authors' surgical procedures for preventing postoperative malalignme... | ['Collateral Ligaments', 'Female', 'Humans', 'Infant', 'Male', 'Orthopedic Procedures', 'Polydactyly', 'Radiography', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Toes', 'Treatment Outcome'] | 23,096,621 | [['A02.513.514.162', 'A02.835.583.512.162', 'A10.165.669.514.162'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.718', 'E04.555'], ['C05.660.585.600', 'C16.131.621.585.600'], ['E01.370.350.700'], ['E04.680'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500'... | ['Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Forced expiratory flow in uninfected infants and children born to HIV-infected mothers. | The Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV (P(2)C(2) HIV) Study is a multicenter study examining pulmonary and cardiac outcomes in offspring of HIV-infected mothers. This portion of the P(2)C(2) study tests the hypothesis that infants exposed to, but uninfected by, maternal H... | ['Age Factors', 'Analysis of Variance', 'Case-Control Studies', 'Child, Preschool', 'Cohort Studies', 'Female', 'Forced Expiratory Flow Rates', 'HIV Infections', 'Humans', 'Infant', 'Infectious Disease Transmission, Vertical', 'Linear Models', 'Male', 'Pregnancy', 'Probability', 'Reference Values', 'Respiratory Functio... | 11,282,758 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.386.700.660.225', 'G09.... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metabolites of cannabidiol identified in human urine. | 1. Urine from a dystonic patient treated with cannabidiol (CBD) was examined by g.l.c.-mass spectrometry for CBD metabolites. Metabolites were identified as their trimethylsilyl (TMS), [2H9]TMS, and methyl ester/TMS derivatives and as the TMS derivatives of the product of lithium aluminium deuteride reduction. 2. Thirt... | ['Biotransformation', 'Cannabidiol', 'Cannabinoids', 'Dystonia', 'Gas Chromatography-Mass Spectrometry', 'Glucuronates', 'Humans', 'Molecular Structure'] | 2,336,840 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D02.455.849.090.100'], ['D02.455.849.090'], ['C10.597.350.300', 'C23.888.592.350.300'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.241.081.844.915.162', 'D02.241.152.811.162', 'D02.241.511.902.915.162', 'D09.811.922.162'], ['B01.050.150.900.649.313.988.400.112.40... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictors for Increased and Reduced Rat and Mouse Allergen Exposure in Laboratory Animal Facilities. | Introduction: Exposure to rat and mouse allergens during work in laboratory animal facilities represents a risk for being sensitized and developing allergic diseases, and it is important to keep the exposure level as low as possible. The objective of this study was to characterize the personal Mus m 1 and Rat n 1 expos... | ['Air Pollutants, Occupational', 'Air Pollution, Indoor', 'Allergens', 'Animal Technicians', 'Animals', 'Animals, Laboratory', 'Humans', 'Mice', 'Occupational Exposure', 'Rats'] | 29,982,271 | [['D27.888.284.101.268'], ['N06.850.460.100.080'], ['D23.050.063'], ['M01.526.485.067.040', 'N02.360.067.040'], ['B01.050'], ['B01.050.050.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['N06.850.460.350.600'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Environmental assessment of solid waste systems and technologies: EASEWASTE. | A new model has been developed for evaluating the overall resource consumption and environmental impacts of municipal solid waste management systems by the use of life cycle assessment. The model is named EASEWASTE (Environmental Assessment of Solid Waste Systems and Technologies) and is able to compare different waste... | ['Environment', 'Environmental Pollution', 'Models, Theoretical', 'Refuse Disposal', 'Soil', 'Waste Products'] | 16,496,866 | [['G16.500.275', 'N06.230'], ['N06.850.460'], ['E05.599'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.900.600'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D20.944', 'N06.850.460.710']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Botulinum E toxin light chain does not cleave SNAP-23 and only partially impairs insulin stimulation of GLUT4 translocation in 3T3-L1 cells. | The stimulation of glucose uptake into fat and muscle by insulin results predominantly from the translocation of the glucose transporter, GLUT4, from an intracellular vesicle pool to the cell surface. Homologues of several key proteins known to be involved in the process of synaptic vesicle fusion have been identified ... | ['3T3 Cells', 'Amino Acid Sequence', 'Animals', 'Biological Transport', 'Botulinum Toxins', 'Carrier Proteins', 'Glucose Transporter Type 4', 'Humans', 'Hydrolysis', 'Insulin', 'Insulin Antagonists', 'Mice', 'Monosaccharide Transport Proteins', 'Muscle Proteins', 'Qb-SNARE Proteins', 'Qc-SNARE Proteins', 'Recombinant P... | 9,268,721 | [['A11.251.210.100', 'A11.329.228.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G03.143'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['D12.776.157'], ['D12.776.157.530.500.500.937', 'D12.776.157.530.937.563.937', 'D12.776.543.585.500.500.93... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
'One-pot' sequential enzymatic modification of synthetic glycolipids in vesicle membranes. | â(1,4)-Galactosyltransferase (â4Gal-T1) and T. cruzi trans-sialidase (TcTS) have been used in a 'one-pot' cascade to provide vesicles (liposomes) with a trisaccharide coating. These soluble enzymes catalysed the transfer of galactose then sialic acid onto a synthetic N-acetylglucolipid embedded in the bilayers. Cluster... | ['Carbohydrate Sequence', 'Endocytosis', 'Galactosyltransferases', 'Glycolipids', 'Glycoproteins', 'Glycosylation', 'Hep G2 Cells', 'Humans', 'Liposomes', 'Neuraminidase', 'Trisaccharides'] | 29,350,727 | [['G02.111.570.160', 'L01.453.245.667.160'], ['G04.417'], ['D08.811.913.400.450.400'], ['D09.400.410', 'D10.390'], ['D09.400.430', 'D12.776.395'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.479.517', 'D26.255.260.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Compensatory growth in children nourished artificially]. | The features of catch-up growth were studied, with the aid of anthropometric measurements, in 59 malnourished children, under continuous enteral or parenteral nutrition. Normal weight was reached after 4 months and normal height after 10 months. Protein compartment was normalized after 4 months; so was the fat tissue c... | ['Adolescent', 'Body Height', 'Body Weight', 'Child', 'Child, Preschool', 'Enteral Nutrition', 'Growth', 'Humans', 'Infant', 'Nutrition Disorders', 'Parenteral Nutrition', 'Skinfold Thickness'] | 6,819,838 | [['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['M01.060.406.448'], ['E02.421.360', 'E02.642.500.360'], ['G07.345... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adaptation to low dietary calcium in magnesium-deficient rats. | To determine if adaptation to low calcium (Ca) diets is impaired by magnesium (Mg) deficiency, weanling rats were pair-fed control (700 mg Mg/kg diet) or low Mg (70 mg Mg/kg diet) diets containing 5000 mg Ca/g diet for 7 or 10 d. Half of the animals from each group were then killed; the remainder continued on their pre... | ['Adaptation, Physiological', 'Animals', 'Body Weight', 'Bone and Bones', 'Calcitriol', 'Calcium', 'Calcium, Dietary', 'Kidney', 'Magnesium Deficiency', 'Male', 'Minerals', 'Myocardium', 'Organ Size', 'Parathyroid Hormone', 'Rats', 'Rats, Inbred Strains'] | 3,373,338 | [['G07.025', 'G16.012.500'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A02.835.232', 'A10.165.265'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.93... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Animal model of acute deep vein thrombosis. | PURPOSE: To develop an animal model of acute deep vein thrombosis (DVT).METHODS: In part I of the study nine juvenile domestic pigs were used. Each external iliac vein was transluminally occluded with a balloon catheter. Thrombin was infused through a microcatheter in one leg according to one of the following protocols... | ['Animals', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Infusions, Intravenous', 'Reference Values', 'Swine', 'Thrombin', 'Thrombophlebitis'] | 9,688,802 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['E05.978.810'], ['B01.050.150.900.649.313.500.880'], ['D08.811.277.656.300.760.855', 'D08.811.277.656.959.350.855', 'D12.776.124.125.890', 'D23.119.960'], ['C14.907.355.8... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organization of telomere sequences in birds: evidence for arrays of extreme length and for in vivo shortening. | Telomeres are the specialized ends of chromosomes consisting of highly conserved repeat (5'-TTAGGG-3')(n) sequences. Lack of information regarding the existence of an in vivo telomere clock function in birds, conflicting data regarding telomere array length in the chicken model, and the paucity of molecular telomere in... | ['Aging', 'Animals', 'Birds', 'Cell Differentiation', 'Cellular Senescence', 'DNA Restriction Enzymes', 'Endodeoxyribonucleases', 'Erythrocytes', 'Gene Expression Regulation, Developmental', 'Karyotyping', 'Male', 'Repetitive Sequences, Nucleic Acid', 'Spermatozoa', 'Telomere'] | 11,060,464 | [['G07.345.124'], ['B01.050'], ['B01.050.150.900.248'], ['G04.152'], ['G04.043'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D08.811.277.352.335.350', 'D08.811.277.352.355.325'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G05.308.310'], ['E01.370.225.500.385.315', 'E0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancement of lipid productivity in oleaginous Colletotrichum fungus through genetic transformation using the yeast CtDGAT2b gene under model-optimized growth condition. | Oleaginous fungi are of special interest among microorganisms for the production of lipid feedstocks as they can be cultured on a variety of substrates, particularly waste lingocellulosic materials, and few fungal strains are reported to accumulate inherently higher neutral lipid than bacteria or microalgae. Previously... | ['Colletotrichum', 'Diacylglycerol O-Acyltransferase', 'Lipids', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 25,375,973 | [['B01.300.381.235'], ['D08.811.913.050.387'], ['D10'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression and Regulation of Brain Natriuretic Peptide and Natriuretic Peptide Receptor A (NPR-A) in L6-S1 Dorsal Root Ganglia in a Rat Model of Chronic Nonbacterial Prostatitis. | BACKGROUND The study aimed to investigate the expression of brain natriuretic peptide (BNP) and natriuretic peptide receptor A (NPR-A) in L6-S1 dorsal root ganglia (DRG) in a rat model of chronic nonbacterial prostatitis (CNP). MATERIAL AND METHODS One hundred specific pathogen-free (SPF) male Sprague-Dawley rats were ... | ['Animals', 'China', 'Disease Models, Animal', "Freund's Adjuvant", 'Ganglia, Spinal', 'Gene Expression Regulation', 'Male', 'Natriuretic Peptide, Brain', 'Pain', 'Prostatitis', 'Proteins', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Atrial Natriuretic Factor', 'Signal Transduction', 'Transcriptome'] | 31,777,403 | [['B01.050'], ['Z01.252.474.164'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D20.475'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.308'], ['D06.472.699.584.625', 'D12.644.548.585.625', 'D12.776.631.590'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['C12.294.565.750']... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Medical students' gynecologic examination skills. Evaluation by gynecology teaching associates. | In the past it was assumed that medical students would be able to perform an adequate pelvic examination by the end of the third-year clinical clerkship. At the University of Virginia, students completing the clinical clerkship were evaluated by trained gynecology teaching associates (GTAs), acting as patients and chap... | ['Breast Diseases', 'Clinical Clerkship', 'Education, Medical, Undergraduate', 'Evaluation Studies as Topic', 'Female', 'Genital Diseases, Female', 'Gynecology', 'Humans', 'Interpersonal Relations', 'Physical Examination', 'Psychomotor Performance'] | 3,735,261 | [['C17.800.090'], ['I02.358.105'], ['I02.358.399.450'], ['E05.337', 'N05.715.360.335'], ['C13.351.500'], ['H02.403.763.750', 'H02.403.810.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E01.370.600'], ['F02.808', 'G11.427.700', 'G11.561.660']] | ['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
[Massive pulmonary embolism caused by thrombosis formed on a central catheter in a child]. | A case is reported of a 9-year-old girl admitted with a subarachnoid haemorrhage. Her neurological recovery was favourable after the embolization of a cerebral arterio-venous malformation. She stayed in ICU with mechanical ventilation because of a bacterial pneumonia and a post-extubation laryngeal oedema. She required... | ['Catheterization, Central Venous', 'Catheters, Indwelling', 'Child', 'Female', 'Heparin', 'Humans', 'Infant, Newborn', 'Intensive Care Units, Pediatric', 'Intracranial Arteriovenous Malformations', 'Pulmonary Embolism', 'Respiratory Distress Syndrome, Newborn', 'Superior Vena Cava Syndrome', 'Thrombosis'] | 8,311,358 | [['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E07.132.500'], ['M01.060.406'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['N02.278.388.493.390'], ['C10.228.140.300.520', 'C10.500.190.500', 'C14.240.850.750.295', 'C14.240.850.875.500', 'C14.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effect of acupuncture at Baihui (GV 20) and Zusanli (ST 36) on the level of serum inflammatory cytokines in patients with depression]. | OBJECTIVE: To investigate the immunologic mechanism of acupuncture at Baihui (GV 20) and Zusanli (ST 36) for treatment of depression.METHODS: Eighty-four cases of depression patients were randomly divided into an electroacupuncture observation group (group A), an electroacupuncture control group (group B) and a medicat... | ['Acupuncture Points', 'Acupuncture Therapy', 'Adolescent', 'Adult', 'Aged', 'Cytokines', 'Depression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Young Adult'] | 20,496,732 | [['E02.190.044.555.035'], ['E02.190.044'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel basal ganglia pathway forms a loop linking a vocal learning circuit with its dopaminergic input. | Dopamine has been implicated in mediating contextual modulation of motor behaviors and learning in many species. In songbirds, dopamine may act on the basal ganglia nucleus Area X to influence the neural activity that contributes to vocal learning and contextual changes in song variability. Neurons in midbrain dopamine... | ['Animals', 'Basal Ganglia', 'Dopamine', 'Finches', 'Learning', 'Male', 'Nerve Net', 'Neural Pathways', 'Vocalization, Animal'] | 18,398,824 | [['B01.050'], ['A08.186.211.200.885.287.249'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['B01.050.150.900.248.620.750.250'], ['F02.463.425', 'F02.784.629.529'], ['A08.511'], ['A08.612'], ['F01.145.113.055.800']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disparities in Access to Bariatric Surgery in Texas 2013-2017. | Background: Access to bariatric care varies across regions, ethnic, and racial groups. Some of these variations may be due to insurance status or socioeconomic status. There are also regional and state variations in access to metabolic and bariatric surgery (MBS). The Texas Inpatient Public Use Data File (IPUDF) and Te... | ['Adult', 'African Americans', 'European Continental Ancestry Group', 'Female', 'Gastrectomy', 'Gastric Bypass', 'Healthcare Disparities', 'Hispanic Americans', 'Hospitalization', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Texas', 'Young Adult'] | 32,425,480 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.400'], ['E04.210.419'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['N04.590.374.380', 'N05.300.493'], ['M01.686.754.441'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Behavioral thermal tolerances of free-ranging rattlesnakes (Crotalus oreganus) during the summer foraging season. | Increasing temperature due to climate change is one of the greatest challenges for wildlife worldwide. Behavioral data on free-ranging individuals is necessary to determine at what temperatures animals modify activity as this would determine their capacity to continue to move, forage, and mate under altered thermal reg... | ['Animals', 'Body Temperature', 'Climate Change', 'Crotalus', 'Predatory Behavior', 'Seasons', 'Temperature'] | 28,343,580 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G16.500.175.374'], ['B01.050.150.900.833.672.125.937.240.500'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enhanced direct electrochemistry of glucose oxidase and biosensing for glucose via synergy effect of graphene and CdS nanocrystals. | Integrating graphene-based composites with enzyme provides a potent strategy to enhance biosensor performance due to their unique physicochemical properties. Herein we report on the utilization of graphene-CdS (G-CdS) nanocomposite as a novel immobilization matrix for the enzymes, which glucose oxidase (GOD) was chosen... | ['Biosensing Techniques', 'Cadmium Compounds', 'Conductometry', 'Crystallization', 'Equipment Design', 'Equipment Failure Analysis', 'Glucose', 'Glucose Oxidase', 'Graphite', 'Nanostructures', 'Nanotechnology', 'Selenium Compounds'] | 20,947,324 | [['E05.601.043'], ['D01.142'], ['E05.196.922.500', 'E05.301.160'], ['E05.196.300', 'G02.171'], ['E05.320'], ['E05.325.192'], ['D09.947.875.359.448'], ['D08.811.682.047.239'], ['D01.268.150.300', 'D01.578.300'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['D01.810']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Tubuglomerular feedback control in long-looped nephrons. Topical minireview. | The tubuloglomerular feedback mechanism is highly activated in juxtamedullary nephrons and considered to play a major role in intrarenal regulation of glomerular filtration rate. The vasculature of juxtamedullary nephrons is highly vasoreactive with a high ability for vasodilation. This vasoreactivity is a prerequisite... | ['Animals', 'Captopril', 'Feedback', 'Glomerular Filtration Rate', 'Juxtaglomerular Apparatus', 'Kidney Concentrating Ability', 'Kidney Medulla', 'Nephrons', 'Rats', 'Rats, Sprague-Dawley', 'Regional Blood Flow', 'Verapamil'] | 1,471,310 | [['B01.050'], ['D12.125.072.401.623.270'], ['L01.906.394.211'], ['E01.370.390.400.300', 'G08.852.357'], ['A05.810.453.324.359.520', 'A05.810.453.736.520.520'], ['G08.852.536'], ['A05.810.453.466'], ['A05.810.453.736'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G09.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Fusion proteins encoded by orf 129L of ectromelia and orf A30L of smallpox viruses cross-react with neutralizing monoclonal antibodies]. | Open reading frame (orf) 129L of ectromelia (EV) and orf A30L of smallpox viruses (SPV) encoding fusion proteins were cloned and expressed in E. coli cells. The recombinant polypeptides (prA30L H pr129L) were purified from cell lysates by Ni-NTA chromatography. Recombinant polypeptides were able to form trimers in buff... | ['Animals', 'Antibodies, Monoclonal', 'Ectromelia virus', 'Epitopes', 'Recombinant Fusion Proteins', 'Species Specificity', 'Variola virus', 'Viral Proteins'] | 16,358,742 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B04.280.650.160.650.200'], ['D23.050.550'], ['D12.776.828.300'], ['G16.824'], ['B04.280.650.160.650.930'], ['D12.776.964']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Poisson?s ratio of arterial wall - Inconsistency of constitutive models with experimental data. | Poisson?s ratio of fibrous soft tissues is analyzed in this paper on the basis of constitutive models and experimental data. Three different up-to-date constitutive models accounting for the dispersion of fibre orientations are analyzed. Their predictions of the anisotropic Poisson?s ratios are investigated under finit... | ['Anisotropy', 'Arteries', 'Biomechanical Phenomena', 'Mechanical Phenomena', 'Models, Biological', 'Poisson Distribution', 'Stress, Mechanical'] | 26,539,804 | [['G01.590.040', 'G02.050'], ['A07.015.114'], ['G01.154.090', 'G01.374.089'], ['G01.374'], ['E05.599.395'], ['E05.318.740.994.750', 'G17.820.750', 'N05.715.360.750.750.620', 'N06.850.520.830.994.750'], ['G01.374.835']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Midlife insomnia and subsequent mortality: the Hordaland health study. | BACKGROUND: Previous research suggests a possible link between insomnia and mortality, but findings are mixed and well-controlled studies are lacking. The aim of the current study was to examine the effect of insomnia in middle age on all-cause mortality.METHODS: Using a cohort design with 13-15 years follow-up, mortal... | ['Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Norway', 'Registries', 'Risk Assessment', 'Sleep Initiation and Maintenance Disorders', 'Surveys and Questionnaires'] | 25,024,049 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.816.374'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N0... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of controlled ovarian hyperstimulation treatment on cardiac function. | OBJECTIVE: To evaluate the effects of controlled ovarian hyperstimulation (COH) treatment on cardiac functions using tissue Doppler imaging (TDI).STUDY DESIGN: Twenty-one patients aged 22-35 years were enrolled to COH cycles. Each subject underwent a conventional transthoracic echocardiographic examination that include... | ['Adult', 'Blood Pressure', 'Female', 'Follicle Stimulating Hormone, Human', 'Gonadotropin-Releasing Hormone', 'Heart Rate', 'Hormone Antagonists', 'Humans', 'Ovulation Induction', 'Stroke Volume', 'Ventricular Function, Left', 'Ventricular Function, Right', 'Young Adult'] | 21,291,037 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D06.472.699.631.525.343.288.625'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D06.347', 'D27.505.696.399.450'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Coffee and caffeine intake and risk of urinary incontinence: a meta-analysis of observational studies. | BACKGROUND: Previous results from studies on the relationship between coffee/caffeine consumption and risk of urinary incontinence (UI) are inconclusive. We aim to assess this association using a meta-analysis of observational studies.METHODS: Pertinent studies were identified by searching electronic database (Embase, ... | ['Caffeine', 'Coffee', 'Female', 'Humans', 'Male', 'Observational Studies as Topic', 'Risk Assessment', 'Urinary Incontinence'] | 27,716,171 | [['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D20.215.784.249', 'G07.203.100.325', 'J02.200.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.250.500', 'N05.715.360.330.250.500', 'N06.850.520.450.250.500'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Nordic pulse oximetry screening--implementation status and proposal for uniform guidelines. | AIM: Pulse oximetry screening of newborn infants increases early detection of critical congenital heart disease and minimises the risk of circulatory collapse before surgery. This study provides an update on the implementation of pulse oximetry screening in the Nordic countries and proposes standardised guidelines.METH... | ['Algorithms', 'Heart Defects, Congenital', 'Humans', 'Infant, Newborn', 'Neonatal Screening', 'Oximetry', 'Practice Guidelines as Topic', 'Scandinavian and Nordic Countries', 'Surveys and Questionnaires'] | 25,060,211 | [['G17.035', 'L01.224.050'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.910', 'E01.370.500.580', 'E05.200.910', 'E05.318.308.980.438.580.580', 'N02.421.726.233.443.816', 'N05.715.360.300.800.438.500.575', 'N06.850.520.308.980.43... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Seagrass ecosystem services - What's next? | Seagrasses, marine flowering plants, provide a wide range of ecosystem services, defined here as natural processes and components that directly or indirectly benefit human needs. Recent research has shown that there are still many gaps in our comprehension of seagrass ecosystem service provision. Furthermore, there see... | ['Alismatales', 'Aquatic Organisms', 'Conservation of Water Resources', 'Ecosystem', 'Humans', 'Marine Biology', 'Oceans and Seas', 'Public Opinion'] | 28,938,998 | [['B01.650.940.800.575.912.250.618.050'], ['B05.080', 'G16.500.275.725.500.650.075'], ['N06.230.080.100'], ['G16.500.275.157', 'N06.230.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.273.248.750.500', 'H01.277.249.750.500', 'H01.277.750.500'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Elucidation of cellular targets responsible for tetrachlorodibenzo-p-dioxin (TCDD)-induced suppression of antibody responses: II. The role of the T-lymphocyte. | Various immunological assays have been applied by our laboratory in an attempt to assess the role of the T-cell in the TCDD-induced suppression of the antibody response by murine B6C3F1 splenic lymphocytes. Animals were treated in vivo (via gavage) with 1.0 microgram/kg TCDD in corn oil for 5 days before in vitro analy... | ['Animals', 'Cell Division', 'Concanavalin A', 'Dioxins', 'Female', 'Immunosuppressive Agents', 'Interleukin-2', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mitogens', 'Polychlorinated Dibenzodioxins', 'Spleen', 'T-Lymphocytes', 'Time Factors'] | 2,307,581 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D02.309.500', 'D03.383.231'], ['D27.505.696.477.656'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of degree, type, and position of unsaturation on the pKa of long-chain fatty acids. | Titration of a series of C(18) fatty acids yields pK(a) values that decrease with an increasing degree of unsaturation in the fatty acid chain. The pK(a) values of stearic, elaidic, oleic, linoleic, and linolenic acids were studied and compared to values of area per molecule in a spread monolayer of these acids. The de... | ['Adsorption', 'Fatty Acids', 'Hydrochloric Acid', 'Hydrogen-Ion Concentration', 'Linoleic Acid', 'Models, Chemical', 'Oleic Acid', 'Temperature'] | 12,505,514 | [['G01.030', 'G02.020'], ['D10.251'], ['D01.029.260.326', 'D01.210.450'], ['G02.300'], ['D10.251.355.310.515.500', 'D10.251.355.343.500.500'], ['E05.599.495'], ['D10.251.355.325.600.525'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of nitroxynil and closantel activity using ELISA and egg counts against Fasciola hepatica in experimentally and naturally infected cattle. | The responses of cattle infected with Fasciola hepatica to treatment with nitroxynil or closantel were monitored by faecal egg counts and by ELISA assay of anti-fluke antibodies. A first trial with experimentally infected heifers showed an increase in anti-fluke antibody titre as early as 2 weeks post-infection. Eggs w... | ['Animals', 'Antiplatyhelmintic Agents', 'Cattle', 'Cattle Diseases', 'Enzyme-Linked Immunosorbent Assay', 'Fascioliasis', 'Female', 'Nitroxinil', 'Parasite Egg Count', 'Salicylanilides', 'Time Factors'] | 7,550,396 | [['B01.050'], ['D27.505.954.122.250.075.100'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C01.610.335.865.354', 'C01.610.518.424', 'C06.552.664.424'], ['D02.455.426.559.389.657.566.620', 'D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Echocardiographic detection of coronary artery fistula into the pulmonary artery. | A rare case of left coronary artery--pulmonary artery fistula is reported. Transoesophageal echocardiography was capable of precisely demonstrating the origin, the course and the drainage site of the fistula. In contrast, transthoracic echocardiography could visualise a drainage flow in the pulmonary artery only. In co... | ['Arterio-Arterial Fistula', 'Coronary Artery Disease', 'Echocardiography, Transesophageal', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Artery'] | 11,888,824 | [['C14.240.850.984.500', 'C14.907.933.110', 'C16.131.240.850.500', 'C23.300.575.950.150'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Three-dimensional culture of mouse bone marrow cells within a porous polymer scaffold: effects of oxygen concentration and stromal layer on expansion of haematopoietic progenitor cells. | To establish an ex vivo expansion method of haematopoietic progenitor cells (HPCs) and erythroid cells, three-dimensional (3D) cultures of mouse bone marrow cells were performed, employing a porous polyvinyl formal (PVF) resin as a scaffold. In these cultures, the effects of oxygen concentration and co-cultures with st... | ['Animals', 'Cell Culture Techniques', 'Cell Hypoxia', 'Cell Proliferation', 'Coculture Techniques', 'Hematopoietic Stem Cells', 'Mice', 'Oxygen', 'Polyvinyls', 'Porosity', 'Stromal Cells', 'Tissue Scaffolds'] | 20,653,040 | [['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G03.197.300', 'G04.270.300'], ['G04.161.750', 'G07.345.249.410.750'], ['E05.481.500.374'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.992.635.505.500'], ['D01.268.185.550', 'D01.362.670'], ['D... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Insulinoma: poor recognition of clinical features is the major problem in diagnosis. | Traditionally it is taught that hypoglycaemia may cause a clinical picture which mimics a variety of neurological and psychiatric disorders. Yet patients with insulinoma continue to baffle many medical specialists, who presumably are not sufficiently aware of the clinical features of hypoglycaemia. After examining medi... | ['Adenoma, Islet Cell', 'Adolescent', 'Adult', 'Diagnostic Errors', 'Female', 'Gastrins', 'Humans', 'Hypoglycemia', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Proinsulin', 'Time Factors'] | 210,363 | [['C04.557.470.035.100', 'C04.588.274.761.249', 'C04.588.322.475.249', 'C06.301.761.249', 'C06.689.667.249', 'C19.344.421.249'], ['M01.060.057'], ['M01.060.116'], ['E01.354', 'N02.421.450.280'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D12.776.631.650.320'], ['B01.050.150.900.649.31... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A case of angiosarcoma with renal failure caused by recombinant interleukin-2 (rIL-2) and non-steroid anti-inflammatory drug (NSAID)]. | A 77-year-old man was diagnosed to have diabetes. He was hospitalized for appetite loss, weight loss (6 kg/3 months) and right femoral pain. An abnormal shadow was noted on chest X-P. On admission, he was alert and there were no abnormal physical findings except limitation in the range of motion in the right lower extr... | ['Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Femoral Neoplasms', 'Hemangiosarcoma', 'Humans', 'Interleukin-2', 'Kidney Failure, Chronic', 'Male', 'Recombinant Proteins'] | 7,776,536 | [['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C04.588.149.276', 'C05.116.231.343'], ['C04.557.450.795.390', 'C04.557.645.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stability of a surface-bound oligonucleotide duplex inferred from molecular dynamics: a study of single nucleotide defects using DNA microarrays. | Microarray technology uses the sequence dependent hybridization (binding) affinity of surface-bound oligonucleotide strands for the quantification of complex nucleic acid mixtures. In spite of its huge potential in life science and medicine, microarray oligonucleotide hybridization remains far from being understood. Ta... | ['Algorithms', 'DNA', 'Models, Chemical', 'Nucleic Acid Hybridization', 'Oligonucleotide Array Sequence Analysis', 'Oligonucleotides', 'Thermodynamics'] | 19,519,141 | [['G17.035', 'L01.224.050'], ['D13.444.308'], ['E05.599.495'], ['E05.393.661', 'G02.111.611'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['D13.695.578.424'], ['G01.906']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Heterologous recognition in vivo of promoter sequences from the Streptomyces coelicolor dagA gene. | The Streptomyces coelicolor dagA gene that codes for an extracellular agarase was cloned in the closely related bacterium S. lividans and transferred to the distantly related low G+C Gram-positive bacterium Bacillus subtilis and to the far more distantly related Gram-negative bacterium Escherichia coli. S1 nuclease map... | ['Bacillus subtilis', 'Bacterial Proteins', 'Base Sequence', 'Carrier Proteins', 'Chromosome Mapping', 'Cloning, Molecular', 'Escherichia coli', 'Genes, Bacterial', 'Genetic Vectors', 'Glycoside Hydrolases', 'Molecular Sequence Data', 'Plasmids', 'Promoter Regions, Genetic', 'RNA, Bacterial', 'RNA, Messenger', 'Strepto... | 7,681,021 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157'], ['E05.393.183'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A comparison of the cost effectiveness of one-stage versus two-stage bilateral total hip replacement. | Forty patients underwent 80 bilateral primary total hip replacements (THRs) under the same anesthesia (one-stage). Forty other patients who underwent unilateral primary THRs during the same time interval were selected to match the first 40 patients with regard to age, sex, diagnosis, weight, medical comorbidity, type o... | ['Aged', 'Arthroplasty, Replacement, Hip', 'Connecticut', 'Cost Allocation', 'Cost-Benefit Analysis', 'Direct Service Costs', 'Female', 'Hospital Charges', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Retrospective Studies'] | 9,867,298 | [['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['Z01.107.567.875.550.200'], ['N03.219.151.080'], ['N03.219.151.125'], ['N03.219.151.400.325', 'N05.300.375.250'], ['N03.219.262.300', 'N03.219.442.613'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.42... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Correlation between amniotic levels of alpha-MSH, ACTH and beta-endorphin in late gestation and labour in normal and complicated pregnancies. | alpha-MSH, ACTH and beta-endorphin were measured by radioimmunoassay in samples of amniotic fluid collected from the 32nd to the 38th gestational week and at labour from normal pregnancies and pregnancies complicated by gestosis. In normal pregnancies, the concentration of alpha-MSH, ACTH and beta-endorphin remained re... | ['Adolescent', 'Adrenocorticotropic Hormone', 'Adult', 'Amniotic Fluid', 'Female', 'Humans', 'Labor, Obstetric', 'Pre-Eclampsia', 'Pregnancy', 'Pregnancy Trimester, Third', 'alpha-MSH', 'beta-Endorphin'] | 2,178,299 | [['M01.060.057'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['A12.098', 'A16.378.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.68... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Distribution and Antimicrobial Susceptibility of Foodborne Salmonella Serovars in Eight Provinces in China from 2007 to 2012 (Except 2009). | One thousand four hundred ninety-one Salmonella isolates recovered from retail foods including chicken, beef, fish, pork, dumplings, and cold dishes in China in 2007, 2008, 2010, 2011, and 2012 were analyzed for distribution of serotype and antimicrobial susceptibility. A total of 129 Salmonella serotypes were detected... | ['Anti-Bacterial Agents', 'Cephalosporin Resistance', 'Cephalosporins', 'China', 'Drug Resistance, Multiple, Bacterial', 'Fluoroquinolones', 'Food Contamination', 'Food Microbiology', 'Meat', 'Salmonella'] | 28,375,673 | [['D27.505.954.122.085'], ['G06.099.225.500.175', 'G06.225.347.500.175', 'G07.690.773.984.269.347.500.175'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['Z01.252.474.164'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['D03.633.100.810.835.322... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Selective release of follicle-stimulating hormone by 5 alpha-dihydroprogesterone in immature ovariectomized estrogen-primed rats. | The effect of 5 alpha-dihydroprogesterone (5 alpha-DHP) on gonadotropin release was examined in the immature acutely ovariectomized (OVX) rat primed with a low dose of estradiol (E2). Treatment with various doses of 5 alpha-DHP given in combination with E2 increased levels of follicle-stimulating hormone (FSH) but had ... | ['20-alpha-Dihydroprogesterone', 'Animals', 'Castration', 'Circadian Rhythm', 'Dose-Response Relationship, Drug', 'Estradiol', 'Female', 'Follicle Stimulating Hormone', 'Gonadotropin-Releasing Hormone', 'Hypothalamo-Hypophyseal System', 'Luteinizing Hormone', 'Progesterone', 'Rats', 'Rats, Inbred Strains'] | 6,426,534 | [['D04.210.500.745.745.654.829.100', 'D06.472.334.851.687.750.074'], ['B01.050'], ['E04.270.282', 'E04.950.165'], ['G07.180.562.190'], ['G07.690.773.875', 'G07.690.936.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of physico-chemical modification on the immunogenicity of Haemophilus influenzae type b oligosaccharide-CRM(197) conjugate vaccines. | Haemophilus influenzae type b (Hib) poly-ribosyl-ribityl phosphate (PRP) oligosaccharide-CRM(197) conjugate vaccines from two different manufacturers (Hib A and Hib B) were subjected to adverse storage conditions and used to establish correlates between physico-chemical characteristics and immunogenicity. There were ma... | ['Animals', 'Antibodies, Bacterial', 'Bacterial Capsules', 'Bacterial Proteins', 'Blood Bactericidal Activity', 'Chemical Phenomena', 'Chemistry, Physical', 'Circular Dichroism', 'Drug Storage', 'Female', 'Haemophilus Vaccines', 'Immunoglobulin G', 'Mice', 'Mice, Inbred CBA', 'Molecular Weight', 'Oligosaccharides', 'Po... | 11,312,015 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['A20.186'], ['D12.776.097'], ['G09.188.100', 'G12.450.564.204'], ['G02'], ['H01.181.529'], ['E05.196.867.151'], ['E05.916.350'], ['D20.215.894.135.450'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Influence of cardiac action on gas mixing in closed-chest dogs. | We performed single-breath tests in closed-chest, paralyzed, and anesthetized dogs (6 with bilateral vagotomy and 6 with intact vagi) with the heart beating and during cardiac arrest. Repeated cardiac arrest was achieved by ventricular fibrillation and subsequent defibrillation. Twenty-four single-breath tests per dog ... | ['Animals', 'Denervation', 'Dogs', 'Gases', 'Heart', 'Heart Arrest, Induced', 'Helium', 'Lung', 'Oscillometry', 'Respiration', 'Respiratory Dead Space', 'Sulfur Hexafluoride', 'Vagus Nerve'] | 7,559,207 | [['B01.050'], ['E04.525.210'], ['B01.050.150.900.649.313.750.250.216.200'], ['D01.362'], ['A07.541'], ['E04.100.376.374', 'E04.928.220.360'], ['D01.268.613.350', 'D01.362.641.352'], ['A04.411'], ['E05.654'], ['G09.772.705'], ['G09.772.760'], ['D01.303.350.300.900', 'D01.362.820', 'D01.875.812'], ['A08.800.050.050.925',... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo cytokinetic effects of recombinant human growth hormone (rhGH) in patients with advanced breast carcinoma. | We have investigated the possibility of inducing a kinetic recruitment of breast cancer cells by the in vivo administration of recombinant human Growth Hormone (rhGH). Twelve patients with advanced breast cancer received rhGH i.m. for 2 days immediately before the first course of chemotherapy. The following biological ... | ['Aged', 'Breast Neoplasms', 'Cell Division', 'Female', 'Growth Hormone', 'Humans', 'Insulin-Like Growth Factor I', 'Middle Aged', 'Pilot Projects', 'Recombinant Proteins'] | 7,660,852 | [['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prolactin binding to R3230AC mammary carcinoma and liver in hormone-treated and diabetic rats. | Specific 125I-labeled prolactin binding was measured in membrane particles prepared from R3230AC mammary carcinoma and liver of tumor-bearing Fischer rats after either prolactin, estrogen, or lergotrile mesylate treatment, or after the induction of diabetes by streptozotocin. Hormone binding to tumors was decreased by ... | ['Acetonitriles', 'Animals', 'Binding Sites', 'Diabetes Mellitus', 'Ergolines', 'Estradiol', 'Female', 'Insulin', 'Liver', 'Mammary Neoplasms, Experimental', 'Membranes', 'Prolactin', 'Rats', 'Receptors, Cell Surface', 'Streptozocin'] | 188,551 | [['D02.626.080'], ['B01.050'], ['G02.111.570.120'], ['C18.452.394.750', 'C19.246'], ['D03.132.327.287', 'D03.633.400.439'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A03.620'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['A1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nocturnal masseter EMG activity of healthy subjects in a natural environment. | Facial pain of patients with craniomandibular disorders might be caused by muscle overload. However, the activity of masticatory muscles of healthy individuals is still unknown. The aim of this study was therefore a first attempt to clarify this question by recording the masseter muscle activity of healthy subjects dur... | ['Adult', 'Analysis of Variance', 'Circadian Rhythm', 'Craniomandibular Disorders', 'Electrodes', 'Electromyography', 'Environment', 'Facial Pain', 'Female', 'Humans', 'Male', 'Masseter Muscle', 'Muscle Contraction', 'Reproducibility of Results', 'Sex Factors', 'Signal Processing, Computer-Assisted', 'Sleep', 'Time Fac... | 10,439,031 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G07.180.562.190'], ['C05.500.607.221', 'C05.651.243', 'C07.320.610.291'], ['E07.305.250'], ['E01.370.405.255', 'E01.370.530.255'], ['G16.500.275', 'N06.230'], ['C23.888.592.612.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Early positive emotionality as a heterogeneous trait: implications for children's self-regulation. | Young children's positive affect in scripted laboratory procedures and in free-flowing social interactions may reflect the activation of related but distinct aspects of positive emotionality (PE), with different implications for self-regulation. The authors observed children's PE in scripted laboratory procedures and i... | ['Affect', 'Child', 'Female', 'Humans', 'Male', 'Self Concept', 'Social Control, Informal'] | 18,072,854 | [['F01.470.047'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.792'], ['I01.880.630']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Morphological analysis of autoimmune disease in MRL-lpr,Yaa male mice with rapidly progressive systemic lupus erythematosus. | We analyzed morphologically autoimmune disease in MRL/MpJ mice bearing both the Yaa and lpr genes (MRL-lpr,Yaa mice), and compared it with that in MRL/MpJ-lpr/lpr (MRL-lpr) mice, in order to examine the effect of the Yaa gene on lpr-induced tissue-specific immunopathologies. MRL-lpr,Yaa male mice developed glomerulonep... | ['Animals', 'Arthritis', 'Female', 'Genes', 'Glomerulonephritis', 'Lupus Erythematosus, Systemic', 'Lymphocyte Subsets', 'Lymphoproliferative Disorders', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Vasculitis'] | 8,347,770 | [['B01.050'], ['C05.550.114'], ['G05.360.340.024.340'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['C17.300.480', 'C20.111.590'], ['A11.118.637.555.567.550', 'A15.145.229.637.555.567.550', 'A15.382.490.555.567.550'], ['C15.604.515', 'C20.683.515'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.19... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complete mitochondrial genomes of Thai and Lao populations indicate an ancient origin of Austroasiatic groups and demic diffusion in the spread of Tai-Kadai languages. | The Tai-Kadai (TK) language family is thought to have originated in southern China and spread to Thailand and Laos, but it is not clear if TK languages spread by demic diffusion (i.e., a migration of people from southern China) or by cultural diffusion, with native Austroasiatic (AA) speakers switching to TK languages.... | ['China', 'DNA, Mitochondrial', 'Ethnic Groups', 'Genetic Variation', 'Genetics, Population', 'Genome, Mitochondrial', 'Haplotypes', 'Humans', 'Language', 'Logistic Models', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Thailand'] | 27,837,350 | [['Z01.252.474.164'], ['D13.444.308.283.225'], ['M01.686.754', 'N01.224.317'], ['G05.365'], ['H01.158.273.343.335'], ['G05.360.340.360'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.8... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Combination therapy with transarterial chemoembolization and interferon-alpha compared with transarterial chemoembolization alone for hepatitis B virus related unresectable hepatocellular carcinoma. | BACKGROUND AND AIMS: The present study was carried out to test the hypothesis that interferon-alpha (IFN-alpha) treatment would reduce or postpone the recurrence rate and improve the overall survival rate in patients after transarterial chemoembolization (TACE) treatment of hepatitis B virus (HBV) related unresectable ... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Carcinoma, Hepatocellular', 'Chemoembolization, Therapeutic', 'Cisplatin', 'Disease-Free Survival', 'Drug Administration Schedule', 'Female', 'Gelatin', 'Hepatitis B', 'Humans', 'Injections, Intramuscular', 'Interferon-alpha', 'Iodized Oil', 'Kaplan-Meier Estimate', 'Liver Ne... | 19,486,255 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.520.360.150', 'E02.926.500.150'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Artificial sRNAs activating the Gac/Rsm signal transduction pathway in Pseudomonas fluorescens. | In Pseudomonas fluorescens CHA0, the synthesis of antifungal compounds is post-transcriptionally activated by the Gac/Rsm cascade. The two-component system GacS/GacA promotes transcription of three small regulatory RNAs (i.e., sRNAs), RsmX, RsmY, and RsmZ, which remove the regulatory proteins RsmA and RsmE from the rib... | ['Bacterial Proteins', 'Binding Sites', 'Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Genes, Synthetic', 'Genetic Complementation Test', 'Nucleic Acid Conformation', 'Pseudomonas fluorescens', 'RNA, Bacterial', 'RNA, Untranslated', 'RNA-Binding Proteins', 'Signal Transduction'] | 19,214,475 | [['D12.776.097'], ['G02.111.570.120'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['G05.360.340.024.340.465'], ['E05.393.281.526'], ['G02.111.570.820.486', 'G05.360.580'], ['B03.440.400.425.625.625.325', 'B03.660.250.580.590.210'], ['D13.444.735.473'], ['D13.444.735.790'], ['D12.776.157.72... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Volumetric changes in the transferred flap after anterior craniofacial reconstruction. | The goal of craniofacial reconstruction is not only life-saving but also facial aesthetics. From this viewpoint the authors evaluated the facial symmetry of patients after craniofacial reconstruction. The subjects were seven patients reconstructed after craniofacial resections. Their CT or MR images were evaluated just... | ['Adolescent', 'Adult', 'Child', 'Cranial Fossa, Anterior', 'Facial Bones', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Reconstructive Surgical Procedures', 'Skull', 'Skull Base Neoplasms', 'Sphenoid Bone', 'Surgical Flaps', 'Tomography, X-Ray Compute... | 17,048,130 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['A01.456.830.150', 'A02.835.232.781.750.150'], ['A02.835.232.781.324'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E04.680'], ['A02.835.232.781'], ['C04.588.149.721.828', 'C05.116.231.754.829'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Late direct angioplasty in patients with myocardial infarction and fluctuating chest pain. | Myocardial infarctions may be associated with reduced but persistent blood flow to the infarct zone. We developed clinical criteria to select patients likely to have persistent perfusion to the infarct zone in the setting of acute myocardial infarction. Twenty-four consecutive patients with fluctuating pain and/or ST s... | ['Angina Pectoris', 'Angioplasty, Balloon, Coronary', 'Coronary Angiography', 'Coronary Circulation', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardial Reperfusion', 'Time Factors', 'Ventricular Function'] | 1,539,505 | [['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Using data visualization and signal processing to characterize the handwriting process. | INTRODUCTION: Disturbances in handwriting legibility and speed are found among elementary school-aged children. The aim of this paper is to present a set of sophisticated analytical tools suitable for visualization and evaluation of handwriting disturbances.METHODS: Handwriting samples from 30 children, 15 proficient a... | ['Agraphia', 'Child', 'Diagnosis, Computer-Assisted', 'Female', 'Handwriting', 'Humans', 'Male', 'Psychomotor Performance', 'Signal Processing, Computer-Assisted', 'Task Performance and Analysis'] | 17,111,567 | [['C10.597.606.150.500.050', 'C23.888.592.604.150.500.050'], ['M01.060.406'], ['E01.158', 'L01.313.500.750.100.158'], ['L01.559.423.906.539'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['L01.224.800'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Fasciola hepatica procathepsin L3 protein expressed by a baculovirus recombinant can partly protect rats against fasciolosis. | Fasciola hepatica juveniles express immunodominant cathepsin L proteins, which are mainly found in their immature, procathepsin form. A gene encoding such a procathepsin L (FheCL3) was expressed by a baculovirus recombinant and by Saccharomyces cerevisiae. The glycosylated FheCL3 proteins obtained by both systems were ... | ['Amino Acid Sequence', 'Animals', 'Baculoviridae', 'Cathepsin L', 'Cathepsins', 'Enzyme Precursors', 'Fasciola hepatica', 'Fascioliasis', 'Female', 'Molecular Sequence Data', 'Rats', 'Rats, Wistar', 'Recombinant Proteins', 'Vaccination', 'Vaccines, Synthetic'] | 15,811,644 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B04.280.065', 'B04.525.100'], ['D08.811.277.656.224.407', 'D08.811.277.656.262.500.157', 'D08.811.277.656.300.200.157'], ['D08.811.277.656.224'], ['D08.622', 'D12.776.811.243'], ['B01.050.500.500.736.715.408.380.420'], ['C01.610.335.865.354', 'C01.610.518.424'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Forecasting changes in preference over the life span: a qualitative study of African-American men's prostate cancer decision making. | GOALS OF WORK: The goal of this study was to explore the processes by which African-American men, at greatest risk, might forecast and manage health changes as they age if they were diagnosed with prostate cancer.PATIENTS AND METHODS: Twenty-nine African-American men, 40-70 years old, with no history of prostate cancer... | ['Adult', 'African Americans', 'Age Factors', 'Aged', 'Attitude to Health', 'Data Collection', 'Decision Making', 'Focus Groups', 'Follow-Up Studies', 'Forecasting', 'Humans', 'Male', 'Middle Aged', 'Prostatic Neoplasms', 'Quality of Life', 'United States'] | 18,478,274 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F02.463.785.373'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['E05.3... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Moving with music for stroke rehabilitation: a sonification feasibility study. | Gross-motor impairments are common after stroke, but efficacious and motivating therapies for these impairments are scarce. We present a novel musical sonification therapy especially designed to retrain gross-motor functions. Four stroke patients were included in a clinical pre-post feasibility study and were trained w... | ['Aged, 80 and over', 'Brain', 'Cognition', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Memory', 'Middle Aged', 'Motor Skills', 'Movement', 'Music', 'Music Therapy', 'Recovery of Function', 'Social Behavior', 'Stroke', 'Stroke Rehabilitation', 'Tomography, X-Ray Computed'] | 25,773,619 | [['M01.060.116.100.080'], ['A08.186.211'], ['F02.463.188'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['M01.060.116.630'], ['F02.808.260'], ['G07.568', 'G11.427.410'], ['K01.602'], ['E02.190.888.500', 'E02.760.... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Relationship between speaking English as a second language and agitation in people with dementia living in care homes: Results from the MARQUE (Managing Agitation and Raising Quality of life) English national care home survey. | OBJECTIVE: As not speaking English as a first language may lead to increased difficulties in communication with staff and other residents, we (1) tested our primary hypotheses that care home residents with dementia speaking English as a second language experience more agitation and overall neuropsychiatric symptoms, an... | ['Aged', 'Aged, 80 and over', 'Attitude of Health Personnel', 'Caregivers', 'Dementia', 'Disease Management', 'England', 'Female', 'Humans', 'Language', 'Male', 'Nursing Homes', 'Psychomotor Agitation', 'Qualitative Research', 'Quality of Life'] | 28,971,511 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.050', 'N05.300.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['C10.228.140.380', 'F03.615.400'], ['N04.590.607'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['N02.278.825.610'], ['C10.597.350.600'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Organization and sequences of p-hydroxybenzaldehyde dehydrogenase and other plasmid-encoded genes for early enzymes of the p-cresol degradative pathway in Pseudomonas putida NCIMB 9866 and 9869. | The gene (designated pchA) encoding the aldehyde dehydrogenase that is required to metabolise the p-hydroxybenzaldehyde produced by the degradation of p-cresol in Pseudomonas putida NCIMB 9866 and 9869 has been identified on plasmids pRA4000 and pRA500, respectively. The gene lies immediately upstream of the pchC and p... | ['Aldehyde Oxidoreductases', 'Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Cresols', 'Enzymes', 'Intramolecular Transferases', 'Molecular Sequence Data', 'NADP', 'Open Reading Frames', 'Plasmids', 'Pseudomonas putida', 'Recombinant Proteins'] | 10,565,539 | [['D08.811.682.657.163'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.455.426.559.389.657.239'], ['D08.811'], ['D08.811.399.520'], ['L01.453.245.667'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Titanium-zirconium narrow-diameter versus titanium regular-diameter implants for anterior and premolar single crowns: 1-year results of a randomized controlled clinical study. | AIM: To test whether titanium-zirconium (TiZr) 3.3 mm diameter implants perform differently from titanium (Ti) 4.1 mm diameter implants with respect to marginal bone level (MBL) and clinical parameters.MATERIAL AND METHODS: Forty subjects in need of a single implant-supported crown in the anterior or premolar regions w... | ['Absorbable Implants', 'Adult', 'Aged', 'Aged, 80 and over', 'Bicuspid', 'Bone Substitutes', 'Crowns', 'Cuspid', 'Dental Implant-Abutment Design', 'Dental Implants, Single-Tooth', 'Dental Materials', 'Dental Plaque Index', 'Dental Prosthesis Design', 'Dental Prosthesis, Implant-Supported', 'Female', 'Follow-Up Studies... | 24,015,975 | [['E07.695.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A14.549.167.860.150'], ['D25.130.325', 'J01.637.051.130.325'], ['E06.780.346.250', 'E07.695.190.088'], ['A14.549.167.860.200'], ['E06.780.346.625.500', 'E06.912.145.750'], ['E06.780.346.593.185', 'E07.695.185.185'], ['D25.339', 'D27.720.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Do pancreatic islet cells from neonatal rats have surface receptors or sensors for divalent cations? | The effects of extracellular divalent cations on the intracellular Ca2+ concentration ([Ca2+]i) in neonatal rat islet cells were investigated to determine whether these cells, like several others, have signal-generating surface cation sensors. Raising the external Ca2+ concentration by 1 mM increments triggered either ... | ['Animals', 'Animals, Newborn', 'Calcium', 'Calcium Channel Blockers', 'Calcium Channels', 'Cations, Divalent', 'Cells, Cultured', 'Female', 'Fluorescent Dyes', 'Fura-2', 'Ion Transport', 'Islets of Langerhans', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Cell Surface', 'Signal Transduction'] | 8,519,594 | [['B01.050'], ['B01.050.050.282'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['D01.248.497.300.333'], ['A11.251'], ['D27.720.233.348', 'D27.720.470.410.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TLR2 haplotypes in the susceptibility to and severity of Chlamydia trachomatis infections in Dutch women. | Chlamydia trachomatis infections may cause several disease conditions ranging from asymptomatic infections to severe upper genital tract pathology, thereby causing significant morbidity worldwide. Remarkable interindividual differences in the clinical course of C. trachomatis infection have been observed, and are mainl... | ['Adolescent', 'Adult', 'Chlamydia Infections', 'Chlamydia trachomatis', 'Female', 'Genetic Predisposition to Disease', 'Genital Diseases, Female', 'Haplotypes', 'Humans', 'Netherlands', 'Polymorphism, Single Nucleotide', 'Toll-Like Receptor 2'] | 20,011,697 | [['M01.060.057'], ['M01.060.116'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.190.750'], ['C23.550.291.687.500', 'G05.380.355'], ['C13.351.500'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Biochemical characterization and sequence analysis of a xylanase produced by an exo-symbiotic bacterium of Gryllotalpa orientalis, Cellulosimicrobium sp. HY-12. | An exo-symbiotic bacterium capable of hydrolyzing xylan was isolated from the gut of the mole cricket, Gryllotalpa orientalis, and identified as Cellulosimicrobium sp. HY-12. The xylanase (XylA( CspHY-12)) of this organism bound tightly to both DEAE and mono Q resins, and its molecular mass (M(r)) was about 39.0 kDa. T... | ['Actinomycetales', 'Amino Acid Sequence', 'Animals', 'Endo-1,4-beta Xylanases', 'Enzyme Stability', 'Gryllidae', 'Molecular Sequence Data', 'Sequence Alignment', 'Substrate Specificity', 'Symbiosis'] | 18,027,102 | [['B03.510.024.049'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.277.450.950.249'], ['E05.916.360', 'G02.111.700.500'], ['B01.050.500.131.617.678.410'], ['L01.453.245.667'], ['E05.393.751'], ['G02.111.835'], ['G06.550.800', 'G16.840']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Maternal serum and umbilical cord tumor marker levels at term pregnancy. | BACKGROUND: The aim of the study was to compare the levels in fetal and maternal compartments of cancer antigen (CA) 125, CA 15-3, carbohydrate antigen (CA) 19-9, and carcinoembryonic antigen (CEA) and to determine the effects of fetal sex, parity, and fetal weight on umbilical cord (UC) and maternal serum (MS) levels ... | ['Adult', 'Biomarkers, Tumor', 'Cesarean Section', 'Female', 'Fetal Weight', 'Humans', 'Parity', 'Pregnancy', 'Reference Values', 'Sex Factors', 'Umbilical Cord'] | 15,603,573 | [['M01.060.116'], ['D23.101.140'], ['E04.520.252.500'], ['C23.888.144.300', 'E01.370.600.115.100.160.120.300', 'E05.041.124.160.750.300', 'G07.100.100.160.120.300', 'G07.345.249.314.120.300', 'G07.345.500.325.235.937', 'G08.686.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.677', 'G08.686.784.769.472... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of complications following posterior vertebral column resection for the treatment of severe angular kyphosis greater than 100°. | OBJECTIVE: The aim of this study was to evaluate the complications, efficacy and safety of posterior vertebral column resection (PVCR) in severe angular kyphosis (SAK) greater than 100°.METHODS: The medical records of 17 patients (mean age 17.9 (range, 9-27) years) with SAK who underwent PVCR, were reviewed. Mean follo... | ['Adolescent', 'Adult', 'Child', 'Female', 'Humans', 'Incidence', 'Kyphosis', 'Lumbar Vertebrae', 'Male', 'Orthopedic Procedures', 'Postoperative Complications', 'Radiography', 'Retrospective Studies', 'Severity of Illness Index', 'Treatment Outcome', 'Turkey', 'Young Adult'] | 28,526,568 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['C05.116.900.800.500'], ['A02.835.232.834.519'], ['E02.718', 'E04.555'], ['C23.550.767'], ['E01.370.350.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Quality of life predicts outcome of deep brain stimulation in early Parkinson disease. | OBJECTIVE: To investigate predictors for improvement of disease-specific quality of life (QOL) after deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson disease (PD) with early motor complications.METHODS: We performed a secondary analysis of data from the previously published EARLYSTIM study, a... | ['Deep Brain Stimulation', 'Follow-Up Studies', 'Humans', 'Parkinson Disease', 'Prognosis', 'Quality of Life'] | 30,737,338 | [['E02.331.300', 'E04.190'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['E01.789'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Streptomyces luridus So3.2 from Antarctic soil as a novel producer of compounds with bioemulsification potential. | The present study aimed to identify novel microbial producers of bioemulsificant compounds from Antarctic soils. Fifty-nine microbial strains were isolated from five different locations at South Shetland Islands, Antarctica, and screened for biosurfactant production by â-hemolytic activity. Strain So 3.2 was determined... | ['Antarctic Regions', 'Biodegradation, Environmental', 'Cell-Free System', 'Culture Media', 'Emulsifying Agents', 'Hydrocarbons', 'Soil Microbiology', 'Streptomyces'] | 29,684,071 | [['Z01.158'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['A11.284.835.168'], ['D27.720.470.305', 'E07.206'], ['D27.720.877.383'], ['D02.455'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['B03.300.390.400.810.768', 'B03.510.024.997.775', 'B03.510.415.400.810.768', 'B03.510.460.410.810.768']] | ['Geographicals [Z]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Luminescent Mycena: new and noteworthy species. | Seven species of Mycena are reported as luminescent, representing specimens collected in Belize, Brazil, Dominican Republic, Jamaica, Japan (Bonin Islands), Malaysia (Borneo) and Puerto Rico. Four of them represent new species (Mycena luxaeterna, M. luxarboricola, M. luxperpetua, M. silvaelucens) and three represent ne... | ['Agaricales', 'Luminescence'] | 20,361,513 | [['B01.300.179.100'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human periosteum is a source of cells for orthopaedic tissue engineering: a pilot study. | BACKGROUND: Periosteal cells are important in embryogenesis, fracture healing, and cartilage repair and could provide cells for osteochondral tissue engineering.QUESTIONS/PURPOSE: We determined whether a population of cells isolated from human periosteal tissue contains cells with a mesenchymal stem cell (MSC) phenotyp... | ['Adult', 'Aged', 'Alkaline Phosphatase', 'Antigens, Surface', 'Biomarkers', 'Bone Development', 'Calcification, Physiologic', 'Cells, Cultured', 'Colony-Forming Units Assay', 'Female', 'Gene Expression', 'Humans', 'Male', 'Mesenchymal Stem Cells', 'Middle Aged', 'Periosteum', 'Phenotype', 'Pilot Projects', 'Tibia', 'T... | 21,547,415 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.277.352.650.035'], ['D23.050.301'], ['D23.101'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['A11.251'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['G... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
The Rotterdam Study: 2018 update on objectives, design and main results. | The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, otolaryngological, locomotor, and respiratory diseases. As of 2008, 14,926 subjects aged 45 years... | ['Aged', 'Aged, 80 and over', 'Chronic Disease', 'Epidemiologic Research Design', 'Female', 'Humans', 'Life Expectancy', 'Male', 'Middle Aged', 'Netherlands', 'Population Surveillance', 'Prospective Studies', 'Risk Factors'] | 29,064,009 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.291.500'], ['E05.318.370', 'N05.715.360.325', 'N06.850.520.445'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.450', 'N01.224.935.464', 'N06.850.505.400.975.450', 'N06.850.520.308.985.450'], ['M01.060.116.630'], ['Z01.542.651'], ['E05.318.30... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The course of the mandibular canal in fossils and forensic material]. | Authors have studied 220 fossil and 44 postmortem mandible-halves by measurements at identical points and in transverse slices cut in the plane of the teeth P2-M3. Parameters relevant to the course of the mandibular canal are summarized. Data add to the knowledge concerning the anatomy and topography of the mandible. | ['Cadaver', 'Forensic Dentistry', 'Fossils', 'Humans', 'Mandible'] | 2,716,752 | [['C23.550.260.224'], ['H02.163.285', 'I01.198.780.875'], ['I01.076.368.584.311'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632', 'A14.521.632']] | ['Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
The effect of pressure on the molecular complex of isoalloxazine and adenine. | The effect of pressure to 10 kilobars on the fluorescence characteristics of flavin mononucleotide (FMN), flavin-adenine dinucleotide (FAD), and on complexes of FMN with adenylic acid (AMP), and with I(-) has been studied. The properties measured include peak location, fluorescence yield, and lifetime. From these resul... | ['Adenine', 'Adenosine Monophosphate', 'Flavin Mononucleotide', 'Flavin-Adenine Dinucleotide', 'Flavins', 'Molecular Conformation', 'Pressure', 'Spectrometry, Fluorescence', 'Thermodynamics'] | 4,524,637 | [['D03.633.100.759.138'], ['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['D03.633.100.733.315.650.500', 'D03.633.300.507.650.500', 'D08.211.474.650.500', 'D13.695.827.349', 'D23.767.405.650.500'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Potent Oral Hypoglycemic Agents for Microvascular Complication: Sodium-Glucose Cotransporter 2 Inhibitors for Diabetic Retinopathy. | The purpose of this study was to investigate the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on the progression of diabetic retinopathy (DR) in patients with type 2 diabetes. The medical records of 21 type 2 diabetic patients who used a SGLT2i and 71 patients with sulfonylurea (control) were reviewed ... | ['Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Diabetic Retinopathy', 'Disease Progression', 'Female', 'Humans', 'Hypoglycemic Agents', 'Male', 'Middle Aged', 'Retrospective Studies', 'Severity of Illness Index', 'Sodium-Glucose Transporter 2 Inhibitors', 'Treatment Outcome'] | 30,622,970 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.33... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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