Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Heat Shock Protein 70 (HSP70) Reduces Hepatic Inflammatory and Oxidative Damage in a Rat Model of Liver Ischemia/Reperfusion Injury with Hyperbaric Oxygen Preconditioning. | BACKGROUND Several clinical conditions can cause hepatic ischemia/reperfusion (I/R) injury. This study aimed to determine the mechanism of the protective effect of hyperbaric oxygen preconditioning (HBO₂P) on hepatic ischemia/reperfusion (I/R) injury in a rat model, and to investigate the effects on HBO₂P and I/R injur... | ['Animals', 'Aspartate Aminotransferases', 'Disease Models, Animal', 'HSP70 Heat-Shock Proteins', 'Hyperbaric Oxygenation', 'Immunohistochemistry', 'Interleukin-6', 'L-Lactate Dehydrogenase', 'Liver', 'Liver Diseases', 'Male', 'Oxidative Stress', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Reperfusion Injury'... | 30,417,859 | [['B01.050'], ['D08.811.913.477.700.225'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.580.216.375'], ['E02.880.690.490'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Hydronephrosis in Schinzel-Giedion syndrome: an important clue for the diagnosis. | Schinzel-Giedion syndrome is a rare autosomal recessive disorder characterized by coarse facies, midface retraction, hypertrichosis, multiple skeletal anomalies, and cardiac and renal malformations. Craniofacial abnormalities of this syndrome sometimes resemble a storage or metabolic disease. The pathogenesis of the di... | ['Abnormalities, Multiple', 'Face', 'Facies', 'Fatal Outcome', 'Female', 'Humans', 'Hydronephrosis', 'Infant, Newborn', 'Kidney', 'Syndrome'] | 15,122,424 | [['C16.131.077'], ['A01.456.505'], ['C23.550.291.812', 'E01.370.600.230'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.307', 'C13.351.968.419.307'], ['M01.060.703.520'], ['A05.810.453'], ... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Risk factors for preeclampsia in twin pregnancies: a population-based matched case-control study. | OBJECTIVE: To evaluate associated factors for preeclampsia in twin gestations and to compare incidences of pregnancy complications among twin pregnancies with vs. without preeclampsia.PATIENTS AND METHODS: We performed a case-control study using a population dataset of twin pregnancies delivered after 24 weeks of gesta... | ['Adult', 'Body Mass Index', 'Case-Control Studies', 'Diabetes, Gestational', 'Female', 'Gestational Age', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Parity', 'Placenta Diseases', 'Pre-Eclampsia', 'Pregnancy', 'Pregnancy, Twin', 'Risk Factors', 'Slovenia'] | 22,752,768 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Natural rubber latex allergy: prevalence and risk factors in patients with spina bifida compared with atopic children and controls. | UNLABELLED: Type 1 allergy against natural rubber latex is an increasing problem in health care workers and children with spina bifida or urogenital malformations. The aim of our study was to evaluate the prevalence of latex IgE antibodies and cross-reacting fruit antibodies in patients with spina bifida compared with ... | ['Adolescent', 'Adult', 'Antibodies, Anti-Idiotypic', 'Child', 'Child, Preschool', 'Female', 'Food Hypersensitivity', 'Humans', 'Hypersensitivity, Immediate', 'Immunoenzyme Techniques', 'Immunoglobulin E', 'Latex', 'Male', 'Middle Aged', 'Prevalence', 'Risk Factors', 'Spinal Dysraphism'] | 9,461,356 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['M01.060.406'], ['M01.060.406.448'], ['C20.543.480.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D12.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Maximizing diagnostic information from the dexamethasone suppression test. An approach to criterion selection using receiver operating characteristic analysis. | Receiver operating characteristic analysis yields indices of diagnostic performance that permit innovative mathematical descriptions and comparisons of diagnostic tests whose results are distributed over a range of possible outcomes. We employed data from seven published studies to demonstrate how ROC analysis may be u... | ['Binding, Competitive', 'Depressive Disorder', 'Dexamethasone', 'Evaluation Studies as Topic', 'Humans', 'Hydrocortisone', 'Psychiatric Status Rating Scales', 'ROC Curve', 'Radioimmunoassay', 'Sensitivity and Specificity'] | 2,660,771 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['F03.600.300'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['F04.711.513.653'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A conceptual demonstration of freeze desalination-membrane distillation (FD-MD) hybrid desalination process utilizing liquefied natural gas (LNG) cold energy. | The severe global water scarcity and record-high fossil oil price have greatly stimulated the research interests on new desalination technologies which can be driven by renewable energy or waste energy. In this study, a hybrid desalination process comprising freeze desalination and membrane distillation (FD-MD) process... | ['Algorithms', 'Distillation', 'Drinking Water', 'Freezing', 'Membranes, Artificial', 'Models, Chemical', 'Permeability', 'Polyvinyls', 'Porosity', 'Pressure', 'Reproducibility of Results', 'Salinity', 'Sodium Chloride', 'Temperature', 'Time Factors'] | 22,682,269 | [['G17.035', 'L01.224.050'], ['E05.196.155.249'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E05.599.495'], ['G02.723'], ['D02.455.326.271.665... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
[Evaluation of a pectin with a low degree of esterification as a prophylactic agent in lead poisoning]. | In experiments with rats, which were undergoing priming by mouth with an acetic lead solution at the rate of 6 mg/day for 1 1/2 month, the prophylactic effect of apple pectin esterified to the degree of 26 per cent (doses 36 and 72 mg) and of 32 per cent (doses of 216 and 432 mg) was evaluated. The best prophylactic ef... | ['Animals', 'Dose-Response Relationship, Drug', 'Drug Evaluation, Preclinical', 'Esterification', 'Lead', 'Lead Poisoning', 'Male', 'Pectins', 'Rats', 'Time Factors'] | 433,235 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical Impact of Preoperative Sentinel Lymph Node Imaging With SPECT/CT in the Management of Interscapular Malignant Melanoma. | A 31-year-old male patient with a biopsy-proven cutaneous malignant melanoma located in the interscapular area was referred to lymphoscintigraphy for preoperative sentinel lymph node mapping. Anterior and posterior planar images showed 3 hot spots suggesting left axillary sentinel nodes. Herein, we reported the contrib... | ['Adult', 'Humans', 'Image-Guided Biopsy', 'Lymphoscintigraphy', 'Male', 'Melanoma', 'Sentinel Lymph Node Biopsy', 'Tomography, Emission-Computed, Single-Photon', 'Tomography, X-Ray Computed'] | 26,053,719 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.384.100.370', 'E01.370.225.998.054.370', 'E01.370.388.100.370', 'E04.074.370', 'E05.200.500.384.100.370', 'E05.200.998.054.370', 'E05.242.384.100.370'], ['E01.370.350.710.299', 'E01.370.384.730.176'], ['C04.557.465.625.650.510', 'C04.5... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
EMG activities in mono- and bi-articular thigh muscles in combined hip and knee extension. | 8 male subjects were tested to elucidate the organization of EMG activities in mono- and bi-articular thigh muscles when hip and knee extension are combined. 2 types of isometric movement, single and dual joint movements, were studied: 1) 20% of maximal voluntary contraction (MVC) in separate hip extension (HE20) and k... | ['Adolescent', 'Adult', 'Biomechanical Phenomena', 'Electromyography', 'Hip Joint', 'Humans', 'Knee Joint', 'Male', 'Muscles', 'Thigh'] | 3,220,066 | [['M01.060.057'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E01.370.405.255', 'E01.370.530.255'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['A02.633', 'A10.690'], ['A01.378.610.750']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Experimental characterization of a vector Doppler system based on a clinical ultrasound scanner. | We have developed a vector Doppler system using a clinical ultrasound scanner with a research interface. In this system, vector Doppler estimation is performed by electronically dividing a linear array transducer into a transmit sub-aperture and two receive sub-apertures. The receive beams are electronically steered, a... | ['Algorithms', 'Biomedical Engineering', 'Calibration', 'Equipment Design', 'Humans', 'Nervous System Diseases', 'Phantoms, Imaging', 'Reproducibility of Results', 'Signal Processing, Computer-Assisted', 'Transducers', 'Ultrasonography, Doppler'] | 19,965,161 | [['G17.035', 'L01.224.050'], ['H02.070', 'J01.293.140'], ['E05.978.155'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10'], ['E07.671'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['L01.224.800'], ['E07.305.812'], ['E01.370.350.850.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
A comparison of tocolysis with nifedipine or ritodrine: analysis of efficacy and maternal, fetal, and neonatal outcome. | Nifedipine, a dihydropyridone calcium entry blocker, has been used with increasing frequency in the treatment of preterm labor. We studied 66 patients in this prospective, randomized trial to evaluate the efficacy and maternal, fetal, and neonatal outcome associated with tocolysis with nifedipine or ritodrine. Delivery... | ['Female', 'Humans', 'Nifedipine', 'Obstetric Labor, Premature', 'Pregnancy', 'Pregnancy Outcome', 'Prospective Studies', 'Randomized Controlled Trials as Topic', 'Ritodrine', 'Tocolytic Agents'] | 2,197,860 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.725.203.540'], ['C13.703.420.491'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Voltage-operated potassium currents in the somatic membrane of rat dorsal root ganglion neurons: ontogenetic aspects. | Whole-cell transmembrane potassium currents were studied in somatic membrane of freshly isolated rat dorsal root ganglion neurons. We defined three types of potassium currents, which were separated on the basis of their different potential dependence of activation and sensitivity to external tetraethylammonium and 4-am... | ['4-Aminopyridine', 'Animals', 'Animals, Newborn', 'Ethylamines', 'Ganglia, Spinal', 'Membrane Potentials', 'Neurons', 'Patch-Clamp Techniques', 'Potassium Channels', 'Rats', 'Rats, Wistar'] | 9,622,247 | [['D02.092.080.060', 'D03.383.725.050.060'], ['B01.050'], ['B01.050.050.282'], ['D02.092.471'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A08.675', 'A11.671'], ['E05.200.500.905', 'E05.242.800'], ['D12.776.157.530.400.600', 'D12.776.54... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biofilm Quantification on Nasolacrimal Silastic Stents After Dacryocystorhinostomy. | PURPOSE: Biofilms are now recognized as potential factors in the pathogenesis of chronic inflammatory and infective diseases. The aim of this study was to examine the presence of biofilms and quantify their biomass on silastic nasolacrimal duct stents inserted after dacryocystorhinostomy (DCR).METHODS: A prospective st... | ['Bacterial Physiological Phenomena', 'Biofilms', 'Biomass', 'Dacryocystorhinostomy', 'Dimethylpolysiloxanes', 'Humans', 'Lacrimal Duct Obstruction', 'Microscopy, Confocal', 'Microscopy, Electron, Scanning', 'Nasolacrimal Duct', 'Prospective Studies', 'Staphylococcus aureus', 'Stents'] | 25,473,887 | [['G06.099'], ['A20.593', 'G06.120'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E04.540.255', 'E04.579.255'], ['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.496.456'], ['E01.370.350.515.395', 'E05.595.395']... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Histopathological aberration in fish skeletal muscle during induced starvation. | Effects of induced starvation on the histology of the fish skeletal muscle, have been studied in the "red muscle" of Heteropneustes fossilis. The tissue has been studied at weekly intervals, for four weeks. The intrafibrillar as well as the interfibrillar nuclei exhibit different behaviour in the red and the white musc... | ['Animals', 'Fishes', 'Muscles', 'Starvation'] | 900,514 | [['B01.050'], ['B01.050.150.900.493'], ['A02.633', 'A10.690'], ['C18.654.521.750']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of swallowing function after supracricoid laryngectomy as a primary or salvage procedure. | The primary functional issues following conservative therapy for advanced laryngeal cancer concern swallowing. Here, we evaluated the recovery of swallowing after supracricoid partial laryngectomy (SCL) in patients with primary or recurrent laryngeal cancer. We evaluated the swallowing recovery in 27 SCL patients throu... | ['Aged', 'Carcinoma, Squamous Cell', 'Cricoid Cartilage', 'Deglutition', 'Female', 'Follow-Up Studies', 'Humans', 'Laryngeal Neoplasms', 'Laryngectomy', 'Male', 'Middle Aged', 'Postoperative Period', 'Quality of Life', 'Retrospective Studies', 'Salvage Therapy', 'Treatment Outcome'] | 26,267,541 | [['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A02.165.257.625.211', 'A02.165.407.500.211', 'A04.329.591.211'], ['G10.261.178'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Magnification--a new look at a long-known optical property of dentin. | Light propagation in human dentin exhibits a strong directional dependence featuring the long-known optical magnification property. We hypothesized that this anisotropic effect is caused by multiple scattering at the dentin tubules, and not by fiberoptic effects, as had been previously assumed. We performed measurement... | ['Anisotropy', 'Dentin', 'Humans', 'Light', 'Microscopy', 'Models, Biological', 'Molar', 'Monte Carlo Method', 'Optics and Photonics', 'Transillumination'] | 16,998,140 | [['G01.590.040', 'G02.050'], ['A14.549.167.900.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['E05.599.395'], ['A14.549.167.860.525'], ['E05.318.740.525', 'L01.906.394.422', 'N05.71... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
[RNA-dependent DNA polymerase from rat liver]. | RNA-dependent DNA-polymerase was isolated from rat liver, and its characteristics were studied. Wistar rat livers were homogenized in the disruptive buffer, centrifuged at 100,000 g and the supernatant was freed of the nucleic acids by DEAE-cellulose (DE-23) chromatography. The further chromatography of the eluate on D... | ['Animals', 'Centrifugation, Density Gradient', 'Chromatography, DEAE-Cellulose', 'Hepatectomy', 'Liver', 'Microsomes, Liver', 'RNA-Directed DNA Polymerase', 'Rats', 'Rats, Inbred Strains', 'Retroviridae', 'Virion'] | 6,206,392 | [['B01.050'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.196.181.400.383.349'], ['E04.210.556'], ['A03.620'], ['A11.284.835.540.541'], ['D08.811.913.696.445.308.300.750', 'D12.776.964.775.375.750', 'D12.776.964.900.750.500.750', 'D12.776.964.970.600.850.375.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of the impact of alternative splicing on protein dynamics: the cases of glutathione S-transferase and ectodysplasin-A isoforms. | Recent studies have shown how alternative splicing (AS), the process by which eukaryotic genes express more than one product, affects protein sequence and structure. However, little information is available on the impact of AS on protein dynamics, a property fundamental for protein function. In this work, we have addre... | ['Alternative Splicing', 'Amino Acid Sequence', 'Animals', 'Anopheles', 'Binding Sites', 'Ectodysplasins', 'Glutathione Transferase', 'Humans', 'Molecular Dynamics Simulation', 'Molecular Sequence Data', 'Protein Conformation', 'Protein Isoforms', 'Sequence Alignment', 'Thermodynamics'] | 22,576,332 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['G02.111.570.120'], ['D12.644.276.374.750.186', 'D12.776.395.550.275', 'D12.776.467.374.750.186', 'D12.776.543.550.275', 'D23.529.374.750... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Oxalate kinetics and reversal of the complications after orthotopic liver transplantation in a patient with primary hyperoxalosis type 1 awaiting renal transplantation. | We present the case of a young woman with end-stage renal disease secondary to primary hyperoxaluria type 1, who after 3 years and 6 months of maintenance hemodialysis, and despite intensification of the dialytic treatment, developed severe livedo reticularis in her extremities leading to ischemic cutaneous ulcerations... | ['Adult', 'Analgesics, Opioid', 'Female', 'Humans', 'Hyperoxaluria, Primary', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Liver Transplantation', 'Pain, Intractable', 'Renal Dialysis', 'Skin Diseases, Vascular', 'Skin Ulcer'] | 10,085,453 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.313.500', 'C13.351.968.419.313.500', 'C16.320.565.202.460', 'C18.452.648.202.460'], ['C12.777.419.780.750.500', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relative numerosity discrimination by chimpanzees (Pan troglodytes): evidence for approximate numerical representations. | Two adult chimpanzees were trained on a relative "numerosity" discrimination task. In each trial, two arrays containing different numbers of red dots were presented on a CRT monitor. The subjects were required to choose the array containing the larger number of dots. In Experiment 1, using numerosities between 1 and 8,... | ['Animals', 'Conditioning, Operant', 'Discrimination Learning', 'Female', 'Learning', 'Mathematics', 'Pan troglodytes', 'Visual Perception'] | 17,443,355 | [['B01.050'], ['F02.463.425.179.509'], ['F02.463.425.280'], ['F02.463.425', 'F02.784.629.529'], ['H01.548'], ['B01.050.150.900.649.313.988.400.112.400.620'], ['F02.463.593.932']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Computational fluid dynamics simulation of transport and retention of nanoparticle in saturated sand filters. | Experimental and computational investigation of the transport parameters of nanoparticles (NPs) flowing through porous media has been made. This work intends to develop a simulation applicable to the transport and retention of NPs in saturated porous media for investigating the effect of process conditions and operatin... | ['Cerium', 'Filtration', 'Hydrodynamics', 'Metal Nanoparticles', 'Models, Theoretical', 'Silicon Dioxide', 'Water Movements'] | 23,270,949 | [['D01.268.558.362.249', 'D01.552.550.399.249'], ['E05.196.454', 'G01.280', 'G02.263'], ['G01.342'], ['J01.637.512.600.500'], ['E05.599'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Altered expression of mitochondrial 16S ribosomal RNA in p53-deficient mouse embryos revealed by differential display. | Inactivation of the tumor suppressor p53 is associated with neural tube defects and altered teratogenicity in early embryos. To gain insight into the function of p53 during early embryogenesis, RNA profiles of wild-type p53(+/+) and p53(-/-) null mutant mouse embryos were compared at the head-fold stage (day 8 post coi... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Animals', 'Chromatography, High Pressure Liquid', 'Embryo, Mammalian', 'Female', 'Gestational Age', 'Mice', 'Mitochondria', 'Polymerase Chain Reaction', 'Pregnancy', 'RNA, Messenger', 'RNA, Ribosomal, 16S', 'Transcription, Genetic', 'Tumor Suppressor Protein p53'] | 9,685,670 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['E05.196.181.400.300'], ['A16.254'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.430.214.190... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Health promotion behaviors in adolescents: prevalence and association with mental health status in a statewide sample. | The purpose of this study is to estimate the proportion of adolescents meeting Healthy People 2020 health behavior recommendations for the prevention of chronic disease and to determine the association between mental health status (depression and/or conduct problems) and the likelihood of meeting these recommendations.... | ['Adolescent', 'Adolescent Behavior', 'Female', 'Health Behavior', 'Health Promotion', 'Health Status', 'Health Surveys', 'Humans', 'Male', 'Mental Health', 'Population Surveillance', 'Prevalence', 'Risk-Taking', 'Washington'] | 24,114,409 | [['M01.060.057'], ['F01.145.022'], ['F01.145.488'], ['I02.233.332.445', 'N02.421.726.407.579'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['E05.318.308... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Porcine rotavirus strain Gottfried-based human rotavirus candidate vaccines: construction and characterization. | Rotavirus gastroenteritis remains the leading cause of severe diarrheal disease in infants and young children worldwide, and thus, a safe and effective rotavirus vaccine is urgently needed in both developing and developed countries. Various candidate rotavirus vaccines that were developed by us and others have been or ... | ['Animals', 'Antibodies, Viral', 'Antigens, Viral', 'Capsid Proteins', 'Guinea Pigs', 'Humans', 'Neutralization Tests', 'RNA, Viral', 'Reassortant Viruses', 'Rotavirus Infections', 'Rotavirus Vaccines', 'Vaccines, Attenuated'] | 15,893,616 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.327'], ['D12.776.964.970.600.550'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.550', 'E05.200.812.735.550', 'E05.478.594.760.550'], ['D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The changing emphasis of mental health and learning disability nurse education in the UK and ideal models of its future development. | This paper reports the findings of a research study funded by the English National Board for Nursing, Midwifery and Health Visiting (ENB), which explored the impact of community care reforms on mental health and learning disability nurses and their practice. In this study we were struck by the divergent views of our re... | ['Community Mental Health Services', 'Forecasting', 'Health Care Reform', 'Humans', 'Intellectual Disability', 'Mental Health', 'Models, Educational', 'Models, Nursing', 'Psychiatric Nursing', 'Specialties, Nursing', 'United Kingdom'] | 9,573,981 | [['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['I01.320'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Characteristics of an MM 22 medical microtron 21 MV photon beam. | Beam quality, surface doses, depths of maximum dose, peak dose rates, beam profiles, and central axis percentage depth doses of a medical microtron's 21 MV photon beam were measured. The half-value layer of lead was 1.35 cm, the half-value layer of water was 23 cm, and the nominal acceleration potential was 17.7 MV. Fo... | ['Humans', 'Radiotherapy, High-Energy', 'Technology, Radiologic'] | 3,922,930 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.815.722'], ['E05.920', 'H02.010.850', 'J01.897.891']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Magnetic resonance imaging detection of aortic and pulmonary artery wall thickening in the acute stage of Takayasu arteritis. Improvement of clinical and radiologic findings after steroid therapy. | OBJECTIVE: Early diagnosis of Takayasu arteritis in the acute stage (prepulseless stage) is extremely difficult. Identification of a useful approach to detecting the initial changes of arteritis is therefore desirable.METHODS: Careful clinical examination of a young woman with persistent fever and dry cough revealed fa... | ['Acute Disease', 'Adult', 'Aorta', 'Aortography', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Prednisolone', 'Pulmonary Artery', 'Takayasu Arteritis', 'Tomography, X-Ray Computed'] | 1,348,939 | [['C23.550.291.125'], ['M01.060.116'], ['A07.015.114.056'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['D04.210.500.745.432.769.795'], ['A07.015.114.715'], ['C14.907.109.239.650', 'C14.907.940.090.800', 'C17.800.862.875'], ['E01.370.350... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Selective protein depletion impairs bone growth and causes liver fatty infiltration in female rats: prevention by Spirulina alga. | Chronic protein malnutrition leads to child mortality in developing countries. Spirulina alga (Spi), being rich in protein and growing easily, is a good candidate as supplementation. We showed that Spi completely prevents bone growth retardation and liver disturbances observed in young rats fed a low protein diet. This... | ['Activins', 'Animals', 'Bone Development', 'Diet, Protein-Restricted', 'Dietary Supplements', 'Fatty Liver', 'Female', 'Fibroblast Growth Factors', 'Follistatin', 'Insulin-Like Growth Factor I', 'Rats', 'Rats, Sprague-Dawley', 'Spirulina'] | 27,341,811 | [['D06.472.334.500', 'D06.472.699.009', 'D12.644.548.009', 'D12.776.395.022'], ['B01.050'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['E02.642.249.280', 'G07.203.650.240.280'], ['G07.203.300.456', 'J02.500.456'], ['C06.552.241'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['D12.776.157.24... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Involvement of nitric oxide in clonidine-induced spinal analgesia. | BACKGROUND: The chronic pain relieving effects following spinal administration of clonidine are probably connected to alpha2-adrenoreceptor-induced augmented synthesis of nitric oxide (NO) in the spinal cord. In contrast, when acute pain is considered, the possible role of NO is still speculative. The aim of the presen... | ['Acute Disease', 'Analgesia', 'Analgesics', 'Animals', 'Arginine', 'Clonidine', 'Injections, Spinal', 'Male', 'Methylene Blue', 'Mice', 'Mice, Inbred ICR', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Nitroglycerin', 'Pain'] | 16,086,555 | [['C23.550.291.125'], ['E03.091'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D03.383.129.308.436.500'], ['E02.319.267.530.580'], ['D02.886.369.517', 'D03.633.300.783.517'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of a tuberculosis screening and prophylaxis program for international students. | In many parts of the world, tuberculosis (TB) is still a major cause of morbidity and mortality. Because of the high rate of worldwide TB infection, the University of California, Los Angeles (UCLA), requires nonimmigrant foreign students to have a tuberculin skin test before completing registration for classes. Out of ... | ['Adolescent', 'Adult', 'Humans', 'International Educational Exchange', 'Los Angeles', 'Mass Screening', 'Patient Compliance', 'Program Evaluation', 'Student Health Services', 'Tuberculosis, Pulmonary'] | 2,299,050 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500.650', 'I02.581'], ['Z01.107.567.875.580.200.450', 'Z01.107.567.875.760.200.450', 'Z01.433.565'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580... | ['Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Allosteric mechanism of induction of CytR-regulated gene expression. Cytr repressor-cytidine interaction. | Transcription from cistrons of the Escherichia coli CytR regulon is activated by E. coli cAMP receptor protein (CRP) and repressed by a multiprotein complex composed of CRP and CytR. De-repression results when CytR binds cytidine. CytR is a homodimer and a LacI family member. A central question for all LacI family prot... | ['Allosteric Regulation', 'Bacterial Proteins', 'Cytidine', 'Dimerization', 'Escherichia coli', 'Escherichia coli Proteins', 'Gene Expression Regulation', 'Kinetics', 'Models, Chemical', 'Models, Molecular', 'Mutation', 'Operon', 'Phenotype', 'Repressor Proteins', 'Transcription, Genetic'] | 9,202,008 | [['G02.111.044'], ['D12.776.097'], ['D03.383.742.680.245', 'D13.570.685.245', 'D13.570.800.286'], ['G02.206', 'G03.230'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.308'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['E05.599.595'], ['G05.365.590'], ['G05.360.340.024.686', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Opioid and nonopioid conditional analgesia: the role of spinal opioid, noradrenergic, and serotonergic systems. | The first aim of this study was to test whether opioid mediation of conditional analgesia is inversely related to the relative amount of training that rats received, a prediction derived from the severity hypothesis. Naltrexone attenuated the analgesia among subjects in the low-training group but had no effect in rats ... | ['Animals', 'Arousal', 'Conditioning, Classical', 'Endorphins', 'Fear', 'Male', 'Nociceptors', 'Norepinephrine', 'Rats', 'Reaction Time', 'Receptors, Adrenergic', 'Receptors, Serotonin', 'Sensory Thresholds', 'Serotonin', 'Spinal Cord', 'Thermosensing'] | 1,667,731 | [['B01.050'], ['F02.830.104', 'G11.561.035'], ['F02.463.425.179.308'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['F01.470.361'], ['A08.675.650.915.875', 'A08.800.950.875', 'A11.671.650.915.875'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Management or leadership? | This article considers the roots of the division between management and leadership, and suggests that the division encourages individuals and organizations to displace responsibility for problems in health services onto others. Given the significant limits to the power of leaders, the difficulty of establishing a scien... | ['Decision Making, Organizational', 'Health Services Administration', 'Humans', 'Leadership', 'Organizational Culture', 'Power, Psychological', 'Problem Solving', 'Social Responsibility'] | 12,425,785 | [['N04.452.190'], ['H02.269', 'N04'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['N04.452.606'], ['F01.658.780'], ['F02.463.425.725', 'F02.463.785.810'], ['F01.829.500.760', 'K01.752.566.869']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterising Uncertainty in Expert Assessments: Encoding Heavily Skewed Judgements. | When limited or no observed data are available, it is often useful to obtain expert knowledge about parameters of interest, including point estimates and the uncertainty around these values. However, it is vital to elicit this information appropriately in order to obtain valid estimates. This is particularly important ... | ['Algorithms', 'Coral Reefs', 'Humans', 'Judgment', 'Models, Theoretical', 'Observer Variation', 'Uncertainty'] | 26,517,835 | [['G17.035', 'L01.224.050'], ['G16.500.275.157.130', 'N06.230.124.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['E05.599'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E05.318.740.600.900', 'F02.463.785.373.820', 'G17.680.875', 'N05.715.360.750.625... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Low level myelomeningoceles: do they need prenatal surgery? | BACKGROUND: Postnatal closure of a myelomeningocele remains the standard of care in many countries. The prenatal closure has given hope for decreasing the damage to the neural placode and has challenged classic management. However, this technique presents potential sources of complications. Patients with MMC with an an... | ['Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Meningomyelocele', 'Neurosurgical Procedures', 'Treatment Outcome'] | 30,915,531 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C10.500.680.610', 'C16.131.666.680.610'], ['E04.525'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Population pharmacokinetic study of tacrolimus in patients with hematopoietic stem cell transplant]. | The present study is to establish the population pharmacokinetic (PPK) model of tacrolimus and to estimate PPK parameters of tacrolimus for the individualization of tacrolimus administration in patients with hematopoietic stem cell transplant. A total of 671 blood samples were collected from 68 hematopoietic stem cell ... | ['Adolescent', 'Adult', 'Child', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Immunosuppressive Agents', 'Male', 'Metabolic Clearance Rate', 'Middle Aged', 'Models, Biological', 'Nonlinear Dynamics', 'Retrospective Studies', 'Tacrolimus', 'Young Adult'] | 20,055,140 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['M01.060.116.630'], ['E05.599.395'], ['E05.599.850', 'H01.54... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
D-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors. | d-serine has been proposed as an endogenous modulator of N-methyl-d-aspartate (NMDA) receptors in many brain regions, but its presence and function in the vertebrate retina have not been characterized. We have detected d-serine and its synthesizing enzyme, serine racemase, in the retinas of several vertebrate species, ... | ['Animals', 'Female', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Racemases and Epimerases', 'Rats', 'Rats, Long-Evans', 'Receptors, N-Methyl-D-Aspartate', 'Retina', 'Serine'] | 12,750,462 | [['B01.050'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D08.811.399.894'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.500'], ['D12.776.157.530.400.400.500.500', 'D12.776.543.550.450.500.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of autologous platelet and plasma products in salvage neck dissections: a prospective clinical study evaluating early and late wound healing. | OBJECTIVES: To evaluate the effect of autologous platelet and plasma adhesives (APA) on postoperative drainage and soft-tissue fibrosis following neck dissections.DESIGN: This was a blinded comparative prospective cohort study done as two parts: part one evaluated early post-surgical outcomes and part two evaluated lat... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Blood Platelets', 'Drainage', 'Female', 'Fibrin Tissue Adhesive', 'Fibrosis', 'Gamma Rays', 'Head and Neck Neoplasms', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Neck Dissection', 'Postoperative Complications', 'Postoperative Period', 'Prospective Studies', 'Skin', '... | 23,648,200 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['A11.118.188', 'A15.145.229.188'], ['E02.309', 'E04.237'], ['D12.776.124.270.305'], ['C23.550.355'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of intraarticular opioid analgesia for the relief of articular pain in the domestic fowl. | An experimental paradigm, based on the microcrystalline sodium urate-induced arthritis pain model, was used to investigate the potential peripheral analgesic properties of a variety of opioid agonists. The response criteria were changes in behavioral profiles and pain-related behaviors over 60 min commencing 1 h after ... | ['Analgesia', 'Analgesics', 'Animals', 'Arthritis, Gouty', 'Buprenorphine', 'Chickens', 'Disease Models, Animal', 'Fentanyl', 'Injections, Intra-Articular', 'Male', 'Morphine', 'Motor Activity', 'Narcotics', 'Pain', 'Receptors, Opioid, mu', 'Uric Acid'] | 10,371,665 | [['E03.091'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['C05.550.114.423.410', 'C05.550.354.500.500', 'C05.799.414.410', 'C16.320.565.798.368.410', 'C18.452.648.798.368.410'], ['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['B01.050.150.900.248.350.150'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Total and out-of-pocket costs of different primary management strategies in ovarian cancer. | BACKGROUND: Communicating healthcare costs to patients is an important component of delivering high-quality value-based care, yet cost data are lacking. This is especially relevant for ovarian cancer, where no clinical consensus on optimal first-line treatment exists.OBJECTIVE: The objective of this study was to genera... | ['Aged', 'Antineoplastic Agents', 'Bevacizumab', 'Chemotherapy, Adjuvant', 'Cohort Studies', 'Cytoreduction Surgical Procedures', 'Deductibles and Coinsurance', 'Female', 'Health Care Costs', 'Health Expenditures', 'Humans', 'Linear Models', 'Middle Aged', 'Neoadjuvant Therapy', 'Ovarian Neoplasms', 'Retrospective Stud... | 30,965,052 | [['M01.060.116.100'], ['D27.505.954.248'], ['D12.776.124.486.485.114.224.060.375', 'D12.776.124.790.651.114.224.060.438', 'D12.776.377.715.548.114.224.200.438'], ['E02.186.170', 'E02.319.170'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.166'], ['N03.219.151.170.300', 'N03.219.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Activated Thiol Sepharose-based proteomic approach to quantify reversible protein oxidation. | Reactive oxygen species (ROS) can act as second messengers in various signaling pathways, and abnormal oxidation contributes to multiple diseases, including cancer. Detecting and quantifying protein oxidation is crucial for a detailed understanding of reduction-oxidation reaction (redox) signaling. We developed an Acti... | ['Animals', 'Carrier Proteins', 'Cells, Cultured', 'Cysteine', 'Dimethyl Fumarate', 'Fumarate Hydratase', 'Membrane Proteins', 'Metabolism, Inborn Errors', 'Muscle Hypotonia', 'Oxidation-Reduction', 'Proteins', 'Proteomics', 'Psychomotor Disorders', 'Rats', 'Sepharose', 'Thyroid Hormones'] | 31,451,050 | [['B01.050'], ['D12.776.157'], ['A11.251'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D02.241.081.337.302.500'], ['D08.811.520.241.300.300'], ['D12.776.543'], ['C16.320.565', 'C18.452.648'], ['C10.597.613.575', 'C23.888.592.608.575'], ['G02.700', 'G03.295.531'], ['D12.776'], ['H01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Nonfreezing Water Structuration in Heteroprotein Coacervates. | Surface-bound water in protein solutions has been identified with a reduction in its freezing point. We studied the presence of such nonfreezing water (NFW) in various protein-polyelectrolyte, micelle-polyelectrolyte, and protein-protein (heteroprotein) coacervates, along with appropriate concentrated solutions of macr... | ['Animals', 'Cattle', 'Electrolytes', 'Lactoferrin', 'Lactoglobulins', 'Micelles', 'Molecular Structure', 'Polymers', 'Serum Albumin, Bovine', 'Surface Properties', 'Water'] | 26,181,078 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D01.248'], ['D08.811.277.656.300.760.471', 'D08.811.277.656.959.350.471', 'D12.776.157.427.750.249', 'D12.776.256.159.750.816.500.507', 'D12.776.377.457.507', 'D12.776.395.507', 'D12.776.556.579.750.249'], ['D12.776.256.159.750.816.500', 'D12.776.377.457'], ['D05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The history and evolution of surgical instruments. VI. The surgical blade: from finger nail to ultrasound. | Elective surgery requires planned incisions and incisions require appropriate blades. In the prehistoric era, division of the umbilical cord and other minor procedures were probably undertaken with human teeth and nails, and later with plant, animal and mineral substitutes, as witnessed by studies of primitive societie... | ['Equipment Design', 'History, 17th Century', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'History, Ancient', 'History, Medieval', 'Humans', 'Metals', 'Nails', 'Surgical Instruments'] | 7,486,768 | [['E05.320'], ['K01.400.504.750'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.470'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.552'], ['A17.600'], ['E07.858.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tolerance of T cell receptor gamma/delta cells in the intestine. | The present study examined the mechanism(s) of tolerance induction for intestinal intraepithelial lymphocytes (iIELs) using an alloantigen (Ag)-specific gamma/delta T cell receptor (TCR gamma/delta) transgenic (Tg) model. In Tg Ag-bearing H-2b/d mice (Tgb/d), Tg iIELs were Thy-1-, CD44+, CD45R (B220)+, and CD5+, wherea... | ['Animals', 'Antigens, Surface', 'Cells, Cultured', 'Chimera', 'Down-Regulation', 'Female', 'Immune Tolerance', 'Interleukin-2', 'Intestines', 'Lymphocyte Activation', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, SCID', 'Receptors, Antigen, T-Cell, ga... | 8,098,732 | [['B01.050'], ['D23.050.301'], ['A11.251'], ['B05.200'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G12.535.425'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374.480.372'], ['A03.556.124'], ['E01.370.225.812.482'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibacterial layer-by-layer coatings to control drug release from soft contact lenses material. | In this study we investigated the possibility of using polyelectrolytes with antibacterial properties to form layer-by-layer (LbL) coatings on contact lens materials with the objective of controlling the release of ophthalmic drugs, while minimizing bacterial growth. A silicone-based hydrogel recently proposed by our g... | ['Administration, Ophthalmic', 'Anti-Bacterial Agents', 'Chemistry, Pharmaceutical', 'Chlorhexidine', 'Contact Lenses, Hydrophilic', 'Cross-Linking Reagents', 'Delayed-Action Preparations', 'Diclofenac', 'Drug Liberation', 'Excipients', 'Models, Theoretical', 'Moxifloxacin', 'Polyelectrolytes', 'Tears'] | 30,342,082 | [['E02.319.267.120.805'], ['D27.505.954.122.085'], ['H01.158.703.007', 'H01.181.466'], ['D02.078.370.141.100'], ['E07.632.500.276.360'], ['D27.720.470.410.210'], ['D26.255.210', 'E02.319.300.253'], ['D02.241.223.601.210'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['D26.650.700.419', 'D27.720.744.770.419'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The daily cost of ICU patients: A micro-costing study in 23 French Intensive Care Units. | OBJECTIVES: To estimate the daily cost of intensive care unit (ICU) stays via micro-costing.METHODS: A multicentre, prospective, observational, cost analysis study was carried out among 21 out of 23 French ICUs randomly selected from French National Hospitals. Each ICU randomly enrolled 5 admitted adult patients with a... | ['APACHE', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Caregivers', 'Costs and Cost Analysis', 'Critical Care', 'Drug Costs', 'Female', 'France', 'Hospitalization', 'Humans', 'Intensive Care Units', 'Laboratories, Hospital', 'Length of Stay', 'Male', 'Middle Aged', 'Prospective Studies'] | 25,986,476 | [['E05.318.308.980.438.475.365', 'E05.318.308.980.438.475.456.500.250', 'N05.715.360.300.800.438.375.364.500.250', 'N06.850.520.308.980.438.475.364.500.250'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['N03.219.151'], ['E02.760.190', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Tensile fatigue failure of acrylic bone cement. | Tensile fatigue tests of acrylic bone cement were conducted under strain control in a wet environment at 37 degrees C. A constant strain rate of 0.02s-1 was used, resulting in physiologic loading frequencies. Comparison of the tensile fatigue data with the results of previous tension-compression fatigue tests indicates... | ['Bone Cements', 'Mathematics', 'Methylmethacrylate', 'Methylmethacrylates', 'Pressure', 'Tensile Strength'] | 6,645,450 | [['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['H01.548'], ['D02.241.081.069.800.550.450', 'D05.750.716.822.111.650.605.450', 'D25.720.716.822.111.650.605.450', 'J01.637.051.720.716.822.111.650.605.450'], ['D02.241.081.069.800.550', 'D05.750.716.822.111.650.605', 'D2... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Metabolism of benzothiazole. I. Identification of ring-cleavage products. | 1. The metabolic fate of benzothiazole in guinea pig has been investigated following i.p. administration at a dose of 30 mg/kg. 2. Five ring-cleavage products were identified in urinary extracts by g.l.c.-mass spectra. By reference to authentic compounds the three major metabolites were shown to be 2-methylmercaptoanil... | ['Animals', 'Benzothiazoles', 'Chromatography, Gas', 'Guinea Pigs', 'Hydrolysis', 'In Vitro Techniques', 'Male', 'Mass Spectrometry', 'Sulfatases', 'Thiazoles'] | 1,788,986 | [['B01.050'], ['D03.383.129.708.089', 'D03.633.100.185'], ['E05.196.181.349'], ['B01.050.150.900.649.313.992.550'], ['G02.380'], ['E05.481'], ['E05.196.566'], ['D08.811.277.352.827'], ['D02.886.675', 'D03.383.129.708']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavior of the chromosome core in mitosis and meiosis. | A simple method has been described for the visualization of chromosomes cores with light microscopy in conventional chromosome preparations. The technique is relatively simple, highly reproducible and can be used effectively on fresh and aged slides. The following observations have been made: (1) a core existed in mito... | ['Animals', 'Carcinoma', 'Cell Line', 'Chickens', 'Chromosomes', 'Colonic Neoplasms', 'Cricetinae', 'Cricetulus', 'Cytological Techniques', 'Female', 'Humans', 'Mammary Neoplasms, Experimental', 'Meiosis', 'Microscopy', 'Mitosis', 'Ovary'] | 7,002,500 | [['B01.050'], ['C04.557.470.200'], ['A11.251.210'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Regional gray matter density associated with emotional intelligence: evidence from voxel-based morphometry. | Emotional Intelligence (EI) is the ability to monitor one's own and others' emotions and the ability to use the gathered information to guide one's thinking and action. EI is thought to be important for social life making it a popular subject of research. However, despite the existence of previous functional imaging st... | ['Brain', 'Brain Mapping', 'Emotional Intelligence', 'Emotions', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Intelligence', 'Magnetic Resonance Imaging', 'Male', 'Statistics as Topic', 'Surveys and Questionnaires', 'Young Adult'] | 20,740,644 | [['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F01.752.543.500'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['F01.752.543'], ['E01.370.350.825.500'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830'], ['E05.318.308.9... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Preparation of gold nanoparticles on eggshell membrane and their biosensing application. | A facile green biosynthesis method has been successfully developed to prepare gold nanoparticles (AuNPs) of various core sizes (25+/-7 nm) using a natural biomaterial, eggshell membrane (ESM) at ambient conditions. In situ synthesis of AuNPs-immobilized ESM is conducted in a simple manner by immersing ESM in a pH 6.0 a... | ['Adsorption', 'Animals', 'Aspergillus niger', 'Biocatalysis', 'Biosensing Techniques', 'Cell Membrane', 'Egg Shell', 'Electrochemistry', 'Enzymes, Immobilized', 'Glucose', 'Glucose Oxidase', 'Gold', 'Hydrogen-Ion Concentration', 'Metal Nanoparticles'] | 20,685,454 | [['G01.030', 'G02.020'], ['B01.050'], ['B01.300.381.081.450'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['E05.601.043'], ['A11.284.149'], ['A13.316'], ['H01.181.529.307'], ['D08.811.180', 'D12.776.463.500'], ['D09.947.875.359.448'], ['D08.811.682.047.239'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Outcome of severe damage to the central nervous system. Scale, scope and philosophy of the clinical problem. | The recovery process after acute brain damage has attracted little interest from either basic or clinical scientists who seem to be most concerned with the acute stage. Much might be learnt about the mechanisms of the nervous system from study of the recovery process. The number of patients with permanent brain damage ... | ['Brain Injuries', 'Cerebrovascular Disorders', 'Disability Evaluation', 'Humans', 'Prognosis'] | 1,045,997 | [['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['C10.228.140.300', 'C14.907.253'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancing Parenting Quality for Young Children Adopted Internationally: Results of a Randomized Controlled Trial. | Children adopted internationally are often dysregulated biologically and behaviorally due to prior experiences of institutional care or caregiving changes and thus are in need of enhanced parental care. The present study assessed whether parents randomized to receive Attachment and Biobehavioral Catch-up (ABC) demonstr... | ['Adult', 'Child', 'Child, Adopted', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Object Attachment', 'Outcome Assessment, Health Care', 'Parenting', 'Parents', 'Republic of Korea'] | 30,649,970 | [['M01.060.116'], ['M01.060.406'], ['M01.100'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['F02.739.794.624'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['F01.829.263.370.310'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', ... | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
MRI appearance does not change in the first 7 days after acute hamstring injury-a prospective study. | BACKGROUND: The optimal timing of MRI following acute hamstring injury is not known and is mainly based on expert opinions.AIMS: To describe the day-to-day changes in the extent of oedema and investigate the optimal timing for detection of fibre disruption on MRI following acute hamstring injuries.STUDY DESIGN: Prospec... | ['Adult', 'Athletic Injuries', 'Edema', 'Humans', 'Leg Injuries', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Prospective Studies', 'Soft Tissue Injuries', 'Thigh', 'Time Factors', 'Young Adult'] | 28,031,188 | [['M01.060.116'], ['C26.115'], ['C23.888.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C26.808'], ['A01.378.610.750'], ['G... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models. | PURPOSE: Glioblastoma multiforme (GBM) is the most aggressive brain tumor. The activity of vosaroxin, a first-in-class anticancer quinolone derivative that intercalates DNA and inhibits topoisomerase II, was investigated in GBM preclinical models as a single agent and combined with radiotherapy (RT).RESULTS: Vosaroxin ... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Biomarkers', 'Cell Line, Tumor', 'Cell Survival', 'Cytokines', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Dose-Response Relationship, Radiation', 'Drug Evaluation, Preclinical', 'Female', 'Glioblastoma', 'Humans', 'Leukocytes', 'Mice', 'Naphthyridin... | 28,415,741 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['D23.101'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hearing recovery and its process from the time of onset in sudden deafness. | A total of 547 patients with idiopathic sudden hearing loss were divided into eight groups according to the days (1-8 days) of their initial visit after onset, and initial hearing thresholds, hearing recovery and its process were investigated. There were no significant differences in initial hearing thresholds and hear... | ['Deafness', 'Hearing', 'Humans', 'Retrospective Studies'] | 8,790,760 | [['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.45... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A revised psychosocial assessment model for implantable pain devices to improve their evidence basis and consensus with updated pain management guidelines. | Although psychosocial evaluations for implantable pain devices have been consensus recommendations since the 1990s, there is an inconsistent support regarding their ability to identify suitable pain device candidates or to predict clinical outcomes. With the emergence of evidence-based practices and the recent release ... | ['Chronic Pain', 'Consensus', 'Electric Stimulation Therapy', 'Evidence-Based Practice', 'Humans', 'Pain Management', 'Pain Measurement', 'Practice Guidelines as Topic', 'Treatment Outcome'] | 30,681,019 | [['C23.888.592.612.274'], ['F01.829.316.068', 'F02.463.785.373.433'], ['E02.331', 'E02.779.468', 'E02.831.535.468'], ['H02.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.745', 'N04.590.607.500'], ['E01.370.600.550.324'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E01.789.800', 'N04.761.559.590.800', '... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Implementing Competency-Based Medical Education in Internal Medicine Residency Training Program: the Process and Impact on Residents' Satisfaction. | BACKGROUND: Graduate medical education is shifting from the traditional apprenticeship model to a competency-driven model. Here we describe the design and implementation of competency-based medical education (CBME) in an internal medicine residency program, and report satisfaction survey results.METHODS: We redesigned ... | ['Adult', 'Competency-Based Education', 'Education, Medical, Graduate', 'Female', 'Humans', 'Internal Medicine', 'Internship and Residency', 'Male', 'Personal Satisfaction', 'Surveys and Questionnaires'] | 31,347,312 | [['M01.060.116'], ['I02.158.210'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F01.145.677'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[The mechanism of the antihypoxic action of indomethacin, voltaren and ibuprofen]. | The antihypoxic effects of indomethacin, voltaren and ibuprofen were studied experimentally by the parameters of acid-base equilibrium of the blood and the ratio of lactic and pyruvic acids in the blood during chronic hemic and respiratory hypoxia. The results of the studies suggested that indomethacin, voltaren and to... | ['Acid-Base Equilibrium', 'Animals', 'Blood Gas Analysis', 'Chronic Disease', 'Diclofenac', 'Drug Evaluation, Preclinical', 'Female', 'Hypoxia', 'Ibuprofen', 'Indomethacin', 'Lactates', 'Lactic Acid', 'Male', 'Pleurisy', 'Pyruvates', 'Pyruvic Acid', 'Rats'] | 3,208,886 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['B01.050'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['C23.550.291.500'], ['D02.241.223.601.210'], ['E05.290.750', 'E05.337.550'], ['C23.888.852.079'], ['D02.241.223.701.430'], ['D03.633.100.473.420'], ['D02.241... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Volatile composition of bilberry wines fermented with non-Saccharomyces and Saccharomyces yeasts in pure, sequential and simultaneous inoculations. | Bilberry (Vaccinium myrtillus L.) juice was fermented with Torulaspora delbrueckii (TD291 and TD70526) and Schizosaccharomyces pombe (SP3796 and SP70572) in pure fermentation as well as in sequential and simultaneous inoculations with Saccharomyces cerevisiae 1116 (SC1116). Altogether, 56 volatile compounds were identi... | ['Anthocyanins', 'Coculture Techniques', 'Fermentation', 'Kinetics', 'Saccharomyces cerevisiae', 'Schizosaccharomyces', 'Torulaspora', 'Vaccinium myrtillus', 'Volatile Organic Compounds', 'Wine'] | 30,704,594 | [['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['E05.481.500.374'], ['G02.111.158.249', 'G03.191.249'], ['G01.374.661', 'G02.111.490'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['B01.300.107.797', 'B01.300.930.720'], ['B01.300.107.795.830', 'B01.300.930.910'], ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Content of quinolinic acid and of other tryptophan metabolites increases in brain regions of rats used as experimental models of hepatic encephalopathy. | The content of the tryptophan metabolites quinolinic acid (QUIN), 5-hydroxytryptamine (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA) was measured in various brain areas of rats bearing a portocaval anastomosis (PCA) for 4 weeks, using mass fragmentography or HPLC. In these animals, the content of the excitotoxic compo... | ['Acetates', 'Animals', 'Brain', 'Brain Stem', 'Cerebellum', 'Cerebral Cortex', 'Disease Models, Animal', 'Hepatic Encephalopathy', 'Hydroxyindoleacetic Acid', 'Male', 'Portacaval Shunt, Surgical', 'Probenecid', 'Pyridines', 'Quinolinic Acid', 'Quinolinic Acids', 'Rats', 'Rats, Inbred Strains', 'Serotonin', 'Tryptophan... | 2,419,500 | [['D02.241.081.018', 'D10.251.400.045'], ['B01.050'], ['A08.186.211'], ['A08.186.211.132'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C06.552.308.500.356', 'C10.228.140.163.360', 'C18.452.132.360'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An RGD-modified endostatin-derived synthetic peptide shows antitumor activity in vivo. | It has been reported that an endostatin-derived synthetic peptide, named ES-2, that contains the amino acids 60-70 of endostatin from its N terminus, efficiently inhibits basic fibroblast growth factor-induced directional migration and tubular morphogenesis of microvascular endothelial cells. We found that the peptide ... | ['Amino Acid Sequence', 'Animals', 'Antineoplastic Agents', 'Cattle', 'Cell Line, Tumor', 'Cell Movement', 'Endostatins', 'Endothelial Cells', 'Female', 'Humans', 'Mice', 'Oligopeptides'] | 18,800,818 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.248'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['D12.644.276.100.450.750', 'D12.776.467.100.450.750', 'D12.776.860.300.250.400.537.500', 'D23.529.100.450.750'], ['A11.436.275'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Study motives, career choices and interest in paediatric dentistry among final year dental students in Nigeria. | BACKGROUND: Students' motives for studying Dentistry have been a subject of interest for years because of the potential for understanding the psychological makeup and subsequent job satisfaction for the dentist. It is also useful in identifying expectations of the profession. This study therefore tried to identify stud... | ['Adult', 'Career Choice', 'Female', 'Humans', 'Male', 'Motivation', 'Nigeria', 'Pediatric Dentistry', 'Students, Dental', 'Surveys and Questionnaires'] | 24,989,055 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['Z01.058.290.190.565'], ['H02.163.876.600'], ['M01.848.769.519'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Carboxyfullerenes as neuroprotective agents. | Two regioisomers with C3 or D3 symmetry of water-soluble carboxylic acid C60 derivatives, containing three malonic acid groups per molecule, were synthesized and found to be equipotent free radical scavengers in solution as assessed by EPR analysis. Both compounds also inhibited the excitotoxic death of cultured cortic... | ['Animals', 'Brain', 'Carboxylic Acids', 'Cell Membrane', 'Free Radicals', 'Humans', 'Mice', 'Neuroprotective Agents'] | 9,256,500 | [['B01.050'], ['A08.186.211'], ['D02.241'], ['A11.284.149'], ['D01.339', 'D02.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.505.696.706.548', 'D27.505.954.427.575']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[DPOAE in high-risk neonatal screening for hearing]. | 64 neonates under intensive care have been tested by distortion product otoacoustic emission (DPOAE) and the auditory brain stem response (ABR) to investigate the value of DPOAE as a test for hearing impairment. The DPOAE test has been found to be practical and quick to perform. The proportion of NICU infants producing... | ['Deafness', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Neonatal Screening', 'Otoacoustic Emissions, Spontaneous', 'Sensitivity and Specificity'] | 11,189,183 | [['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.910', 'E01.370.500.580', 'E05.200.910', 'E05.318.308.980.438.580.580', 'N02.4... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CODE: a deconvolution program implementing a regularization method of deconvolution constrained to non-negative values. Description and pilot evaluation. | A regularization method of deconvolution constrained to non-negative values is described. The method gives smooth estimates of the input function whilst providing a feasible fit (in terms of least squares) to measurements. A description of the program CODE (constrained deconvolution) which implements the method is give... | ['Data Interpretation, Statistical', 'Evaluation Studies as Topic', 'Models, Biological', 'Pharmacokinetics', 'Pilot Projects', 'Software'] | 9,510,984 | [['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.337', 'N05.715.360.335'], ['E05.599.395'], ['G03.787', 'G07.690.725'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[The improvement of poorly water-soluble drug solubility through electrospun drug-loaded nanofibers]. | The improving effect of electrospun drug-loaded nanofibers on the solubility of poorly water-soluble drug was investigated in the present research. Drug-loaded nanofibers were successfully prepared using electrospinning process with helicid as the poorly water-soluble model drug and polyvinylpyrrolidone K60 (PVP K60) a... | ['Benzaldehydes', 'Drug Carriers', 'Drug Compounding', 'Electrochemical Techniques', 'Microscopy, Electron, Scanning', 'Nanofibers', 'Pharmaceutical Preparations', 'Povidone', 'Solubility', 'Spectrophotometry, Ultraviolet', 'X-Ray Diffraction'] | 20,055,145 | [['D02.047.222'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.270'], ['E05.301'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['J01.637.512.300'], ['D26'], ['D02.455.326.271.884.533.699', 'D03.383.773.812.615', 'D05.750.716.721.838', 'D25.720.716.721.838', 'J01.637.051.720.716.721.838'], ['G02.805'], ['E05.196.71... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Brain reward system's alterations in response to food and monetary stimuli in overweight and obese individuals. | The brain's reward system is crucial to understand obesity in modern society, as increased neural responsivity to reward can fuel the unhealthy food choices that are driving the growing obesity epidemic. Brain's reward system responsivity to food and monetary rewards in individuals with excessive weight (overweight and... | ['Adult', 'Aged', 'Analysis of Variance', 'Appetite', 'Body Mass Index', 'Brain', 'Feedback', 'Female', 'Food', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Obesity', 'Overweight', 'Reward', 'Visual Analog Scale'] | 27,659,185 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.071', 'G07.203.650.390.070', 'G10.261.390.070'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A08.186.211'], ['L01.906.394.211'], ['G07.203.300', 'J02.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Broadening of Virus-Specific CD8+ T-Cell Responses Is Indicative of Residual Viral Replication in Aviremic SIV Controllers. | Control of HIV replication is a rare immunological event, providing clues to understand the viral control mechanism. CD8+ T-cell responses are crucial for virus control, but it is unclear whether lasting HIV containment can be achieved after establishment of infection. Here, we describe lasting SIV containment in a mac... | ['Animals', 'CD8-Positive T-Lymphocytes', 'Disease Models, Animal', 'Macaca mulatta', 'Simian Acquired Immunodeficiency Syndrome', 'Simian Immunodeficiency Virus', 'Viral Load', 'Viremia', 'Virus Replication'] | 26,536,034 | [['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['C01.925.782.815.616.850', 'C01.925.839.850', 'C22.735.500.850'], ['B04.820.650.589.650.800', 'B04.820... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rhizosphere microbial densities and trace metal tolerance of the nickel hyperaccumulator Alyssum serpyllifolium subsp. lusitanicum. | In this study we determine culturable microbial densities (total heterotrophs, ammonifiers, amylolytics and cellulolytics) and bacterial resistance to Co, Cr, and Ni in bulk and rhizosphere soils of three populations of the Ni-hyperaccumulator Alyssum serpyllifolium subsp. lusitanicum and the excluder Dactylis glomerat... | ['Biodegradation, Environmental', 'Brassicaceae', 'Environmental Monitoring', 'Geologic Sediments', 'Nickel', 'Plant Roots', 'Soil', 'Soil Pollutants', 'Trace Elements'] | 19,810,353 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['B01.650.940.800.575.912.250.157'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['A18.400'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756'], ['D... | ['Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Suppression of IgE antibody response against ovalbumin by the chemical conjugate of ovalbumin with a polyaspartic acid derivative. | Ovalbumin was modified with alpha,beta-poly[(2-hydroxyethyl)-DL-aspartamide] which had been developed as a nontoxic plasma expander. Preadministration of the modified ovalbumin suppressed both primary and secondary anti-ovalbumin IgE responses. | ['Animals', 'Antibody Formation', 'Immunization', 'Immunoglobulin E', 'Immunosuppression', 'Mice', 'Ovalbumin', 'Passive Cutaneous Anaphylaxis', 'Peptides', 'Rats'] | 3,967,935 | [['B01.050'], ['G12.450.050.370.250'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['E02.095.465.425.450', 'E05.478.610'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Desmin-containing stellate cells in rat liver; distribution in normal animals and response to experimental acute liver injury. | Using immunohistochemical methods, we have confirmed that the perisinusoidal cells in rat liver express the intermediate filament protein, desmin, and we have used this marker for identification of the cells on light microscopy. The study has been extended to quantify the response of perisinusoidal cells to acute liver... | ['Animals', 'Carbon Tetrachloride', 'Desmin', 'Liver', 'Male', 'Necrosis', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 3,783,322 | [['B01.050'], ['D02.455.526.439.150'], ['D05.750.078.593.200', 'D12.776.220.475.200'], ['A03.620'], ['C23.550.717'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of embolization for hemangiomas. | We retrospectively studied 31 patients with painful bone (15 patients) and soft-tissue (16 patients) hemangiomas treated with 39 embolizations using N-2-butyl cyanoacrylate from 2003 to 2010. The mean tumor size before embolization was 6 cm for bone and 7 cm for soft-tissue hemangiomas. The technique of embolization wa... | ['Adult', 'Aged', 'Bone Neoplasms', 'Child', 'Combined Modality Therapy', 'Embolization, Therapeutic', 'Enbucrilate', 'Female', 'Follow-Up Studies', 'Fractures, Compression', 'Fractures, Spontaneous', 'Hemangioma', 'Humans', 'Humeral Fractures', 'Laminectomy', 'Male', 'Middle Aged', 'Pain Management', 'Preoperative Car... | 22,684,541 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['M01.060.406'], ['E02.186'], ['E02.520.360', 'E02.926.500'], ['D02.241.081.069.366.350', 'D02.626.290.350', 'D05.750.259.341', 'D25.720.259.341', 'D25.919.367.341', 'J01.637.051.720.259.341', 'J01.637.051.919.367.341'], ['E05.318.372.500.750.249', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Inhibitory effects of ginseng total saponins on behavioral sensitization and dopamine release induced by cocaine. | Many studies have suggested that the behavioral and reinforcing effects of cocaine can be mediated by the central dopaminergic systems. It has been shown that repeated injections of cocaine produce an increase in locomotor activity, the expression of the immediate-early gene, c-fos, and the release of dopamine (DA) in ... | ['Animals', 'Behavior, Animal', 'Cocaine', 'Dopamine', 'Genes, Immediate-Early', 'Male', 'Microdialysis', 'Motor Activity', 'Nucleus Accumbens', 'Panax', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Rats, Sprague-Dawley', 'Saponins'] | 18,310,906 | [['B01.050'], ['F01.145.113'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G05.360.340.024.340.330', 'G05.360.340.024.340.364.875.345', 'G05.360.340.358.024.875.345', 'G05.360.340.358.840.5... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patient awareness of oral cancer health advice in a dental access centre: a mixed methods study. | OBJECTIVE: In the United Kingdom in 2006, 5,325 persons were diagnosed with oral cancer; and in 2007 it caused around 1,850 deaths. The purpose of this study was to assess the patient awareness, in a dental access centre, of a poster and leaflet campaign providing information about smoking and excess alcohol consumptio... | ['Adult', 'Alcohol Drinking', 'Attitude to Health', 'Consumer Health Information', 'Counseling', 'Dental Clinics', 'Female', 'Health Behavior', 'Health Education, Dental', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Pamphlets', 'Posters as Topic',... | 21,436,799 | [['M01.060.116'], ['F01.145.317.269'], ['F01.100.150', 'N05.300.150'], ['I02.233.332.186', 'N02.421.726.407.229'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['N02.278.192.250'], ['F01.145.488'], ['I02.233.332.374', 'N02.421.726.407.457', 'N06.890.410'], ['F01.100.150.500', 'N05.300.150.410']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Distribution and morphological characteristics of oligodendrocytes in the rat hippocampus in situ and in vitro: an immunocytochemical study with the monoclonal Rip antibody. | Oligodendrocytes in the rat hippocampus in situ and in organotypic slice cultures were studied by light and electron microscopic immunocytochemistry using the monoclonal Rip antibody. Our results confirm that this antibody exclusively stains oligodendrocytes, while astrocytes and neurons are not labelled. In the light ... | ['Animals', 'Antibodies, Monoclonal', 'Hippocampus', 'Immunohistochemistry', 'Oligodendroglia', 'Organ Culture Techniques', 'Rats', 'Rats, Wistar'] | 8,176,418 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Clear cell carcinoma of endometrium. | Three cases of clear cell carcinoma of the endometrium are here reported. Clear cell carcinoma is a rare and aggressive type of endometrial adenocarcinoma. Patients are older and are in the menopause much longer than are patients with typical endometrial carcinoma. This fact may reflect the presence of counterbalanced ... | ['Adenocarcinoma', 'Aged', 'Female', 'Humans', 'Middle Aged', 'Uterine Neoplasms'] | 462,571 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thomas Bruce Ferguson, MD, May 6, 1923-May 26, 2013. | Thomas Bruce Ferguson, the 12th president of The Society of Thoracic Surgeons, died surrounded by his family on May 26, 2013. He was a legendary figure in the world of cardiothoracic surgery. His visionary leadership was an inspiration to generations of cardiothoracic surgeons around the world. | ['History, 20th Century', 'History, 21st Century', 'Oklahoma', 'Thoracic Surgery'] | 24,694,440 | [['K01.400.504.968'], ['K01.400.504.984'], ['Z01.107.567.875.510.550'], ['H02.403.810.803']] | ['Humanities [K]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Shockwave therapy for patients with plantar fasciitis: a one-year follow-up study. | The effect of shockwave therapy was investigated in 79 patients (85 heels) with plantar fasciitis with one-year follow-up. There were 59 women and 20 men with an average age of 47 (range, 15-75) years. Each patient was treated with 1000 impulses of shockwave at 14 kV to the affected heel. A 100-point scoring system was... | ['Adolescent', 'Adult', 'Aged', 'Fasciitis', 'Female', 'Follow-Up Studies', 'Foot Diseases', 'High-Energy Shock Waves', 'Humans', 'Male', 'Middle Aged', 'Pain', 'Pain Management', 'Severity of Illness Index', 'Treatment Outcome'] | 11,934,061 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C05.321'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C05.360', 'C17.800.321'], ['G01.750.770.776.891.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.592.612', 'F02.830.816.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The American Society of Thoracic Surgery Score versus EuroSCORE I and EuroSCORE II in Israeli Patients Undergoing Cardiac Surgery. | BACKGROUND: Recently, Israel established the first national-level adult cardiac surgery database, which was linked to the Society of Thoracic Surgeons (STS).OBJECTIVES: To validate and compare the STS predicted risk of mortality (PROM) to logistic EuroSCORE I (LESI) and EuroSCORE II (ESII) in Israeli patients undergoin... | ['Aged', 'Cardiac Surgical Procedures', 'Databases, Factual', 'Female', 'Humans', 'Israel', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Risk Management', 'Severity of Illness Index', 'Societies, Medical', 'Thoracic Surgery'] | 31,599,509 | [['M01.060.116.100'], ['E04.100.376', 'E04.928.220'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.372.500.500.500', 'E05.318.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
The Genetics of Male Pheromone Preference Difference Between Drosophila melanogaster | Species of flies in the genus Drosophila differ dramatically in their preferences for mates, but little is known about the genetic or neurological underpinnings of this evolution. Recent advances have been made to our understanding of one case: pheromone preference evolution between the species D. melanogaster and D. s... | ['Alkadienes', 'Animals', 'Drosophila', 'Evolution, Molecular', 'Female', 'Genetic Loci', 'Male', 'Mating Preference, Animal', 'Sex Attractants', 'X Chromosome'] | 31,748,379 | [['D02.455.326.271.665.146'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.380'], ['F01.145.113.252.748.300'], ['D23.641.800'], ['A11.284.187.865.982', 'G05.360.162.865.982']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Drinking by rats after lateral hypothalamic lesions: a new look at the lateral hypothalamic syndrome. | Rats that have recovered from aphagia and adipsia following lateral hypothalamic lesions are believed to be incapable of experiencing thirst and to drink water simply to facilitate the consumption of dry food. However, the present results indicate that these animals will drink in response to dehydration of the intracel... | ['Angiotensin II', 'Animals', 'Blood Volume', 'Dehydration', 'Drinking Behavior', 'Feeding Behavior', 'Female', 'Glucose', 'Hypothalamus', 'Intracellular Fluid', 'Male', 'Mesencephalon', 'Rats', 'Renin', 'Substantia Nigra', 'Thirst', 'Time Factors', 'Water Deprivation'] | 1,249,268 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['G09.188.130', 'G09.330.380.092'], ['C18.452.950.179', 'C23.550.274'], ['F01.145.317'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D09.947.875.359.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical treatment of giant spinal neuromas]. | Several cases of successful surgical treatment of giant spinal neuromas are reported in this paper. Benign nature of these tumors promotes radical resection. Localization of giant extravertebral tumor nodes in eloquent areas produces difficulties for total removal. In certain cases single approach is not sufficient for... | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuroma', 'Radiography', 'Spinal Cord Neoplasms'] | 21,374,935 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.580.600.610'], ['E01.370.350.700'], ['C04.588.614.250.803', 'C10.228.854.765', 'C10.551.240.750']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
On testing current cognitive theories of Pavlovian conditioning in the human Pavlovian autonomic transswitching preparation. | The Rescorla-Wagner theory, which Lachnit and Kimmel's transswitching evidence has apparently contradicted, is fundamentally cognitive, inasmuch as it views Pavlovian conditioning as "the learning of relations among events". Kimmel and Lachnit's criticism that Lovibond's theory-saving defence "does little more than imm... | ['Animals', 'Association Learning', 'Cognition', 'Conditioning, Psychological', 'Humans', 'Models, Psychological', 'Reinforcement, Psychology'] | 1,790,272 | [['B01.050'], ['F02.463.425.069.296'], ['F02.463.188'], ['F02.463.425.179'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F02.463.425.770']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Periodontal manifestations and ambulatorial management in a patient with Sturge-Weber syndrome. | Sturge-Weber syndrome is a nonhereditary congenital condition characterized by leptomeningeal and facial skin angiomatous malformation following the trigeminal nerve path. The intraoral angiomatosis are presented in 40% of cases and results in an important periodontal alteration, increasing the risk of bleeding during ... | ['Adult', 'Ambulatory Care', 'Humans', 'Male', 'Periodontal Diseases', 'Sturge-Weber Syndrome'] | 23,147,344 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465.714'], ['C04.557.645.375.850', 'C10.562.800', 'C14.907.077.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of tracheal intubation by the Macintosh laryngoscope and Pentax-AWS (Airway Scope) during chest compression: a manikin study. | To compare tracheal intubation with the Pentax Airway Scope (AWS) and the Macintosh laryngoscope (McL) during chest compression, 25 anesthesiologists (including 12 specialists having >5 years of experience and 13 trainees having <2 years of experience) performed tracheal intubation using either the McL or the AWS, with... | ['Anesthesiology', 'Humans', 'Intubation, Intratracheal', 'Laryngoscopes', 'Laryngoscopy', 'Manikins', 'Time Factors', 'Video-Assisted Surgery'] | 20,127,370 | [['H02.403.066'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E07.230.220.525', 'E07.858.240.525'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['J01.897.280.500.545.129.400', 'L01.178.820.090.545.129.400'], ['G01.910.857'], ['E01.3... | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Segmental analysis of the sagittal plane alignment of the normal thoracic and lumbar spines and thoracolumbar junction. | Recent advances in spinal instrumentation have brought about a new emphasis on the three-dimensional spinal deformity of scoliosis and especially on the restoration of normal sagittal plane contours. Normal alignment in the coronal and transverse planes is easily defined; however, normal sagittal plane alignment is not... | ['Adolescent', 'Adult', 'Aging', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Spine'] | 2,772,721 | [['M01.060.057'], ['M01.060.116'], ['G07.345.124'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In vitro polyvinylformaldehyde particle compatibility with chemotherapeutic drugs used for chemoembolization therapy. | PURPOSE: Because the effects of pirarubicin and carboplatin on the physical structure of particles made from polyvinylformaldehyde are not well known, we describe an experiment to test the in vitro polyvinylformaldehyde particle compatibility with these drugs used for chemoembolization of bone metastases.MATERIALS AND ... | ['Antineoplastic Agents', 'Carboplatin', 'Chemoembolization, Therapeutic', 'Doxorubicin', 'Drug Incompatibility', 'Drug Stability', 'Formaldehyde', 'Hemostatics', 'Humans', 'Immunosuppressive Agents', 'Materials Testing', 'Particle Size', 'Polyvinyl Alcohol', 'Surface Properties'] | 14,562,979 | [['D27.505.954.248'], ['D02.257.125'], ['E02.520.360.150', 'E02.926.500.150'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E05.916.290'], ['E05.916.330'], ['D02.047.407'], ['D27.505.954.502.270.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dynamic changes in level influence spatial coding in the lateral superior olive. | It is well established that the responses of binaural auditory neurons can adapt and change dramatically depending on the nature of a preceding sound. Examples of how the effects of ensuing stimuli play a functional role in auditory processing include motion sensitivity and precedence-like effects. To date, these types... | ['Acoustic Stimulation', 'Adaptation, Physiological', 'Animals', 'Auditory Pathways', 'Evoked Potentials, Auditory, Brain Stem', 'Gerbillinae', 'Olivary Nucleus', 'Sound Localization', 'Synaptic Transmission', 'Time Factors'] | 18,162,347 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['G07.025', 'G16.012.500'], ['B01.050'], ['A08.612.220.110'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['B01.050.150.900.649.313.992.635.300'], ['A08.186.211.132.810.591.500.574'], ['F02.463.593.071.869', 'G07.888.125.869'], ['G02.111.820... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Impact of Hospital Neoadjuvant Therapy Utilization on Survival Outcomes for Pancreatic Cancer. | BACKGROUND: Many surgeons advocate the use of neoadjuvant treatment for resectable pancreatic cancer, however little is known about variation in the utilization of neoadjuvant therapy (NAT) at the hospital level.METHODS: The National Cancer Data Base was used to identify patients undergoing resection for pancreatic can... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Combined Modality Therapy', 'Databases, Factual', 'Female', 'Follow-Up Studies', 'Hospitals, High-Volume', 'Humans', 'Male', 'Neoadjuvant Therapy', 'Pancreatectomy', 'Pancreatic Neoplasms', 'Prognosis', 'Survival Rate'] | 30,003,452 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N02.278.421.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.186.450... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
MutS homologue hMSH5: role in cisplatin-induced DNA damage response. | BACKGROUND: Cisplatin (cis-diamminedichloroplatinum (II), CDDP) and its analogues constitute an important class of anticancer drugs in the treatment of various malignancies; however, its effectiveness is frequently affected by mutations in genes involved in the repair and signaling of cisplatin-induced DNA damage. Thes... | ['Blotting, Western', 'Cell Cycle Proteins', 'Cell Line', 'Cisplatin', 'DNA Breaks, Double-Stranded', 'DNA Damage', 'Humans', 'Immunoprecipitation', 'Phosphorylation', 'RNA Interference'] | 22,401,567 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.167'], ['A11.251.210'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G05.200.210.220'], ['G05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.150.639', 'E05.478.605'], ['G02.111.665', 'G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Triphenyltin as an inhibitor of membrane-bound pyrophosphatase of Rhodospirillum rubrum. | The effect of triphenyltin on the activity of membrane-bound pyrophosphatase of Rhodospirillum rubrum was investigated. Triphenyltin inhibits the hydrolysis of chromatophore membrane-bound pyrophosphatase in a pH-dependent pattern, being maximal at pH 9-10. At basic pH values, the inhibition produced by this organotin ... | ['Dicyclohexylcarbodiimide', 'Enzyme Activation', 'Hydrolysis', 'Membrane Proteins', 'Organotin Compounds', 'Pyrophosphatases', 'Rhodospirillum rubrum', 'Solubility', 'Sulfhydryl Compounds'] | 9,750,176 | [['D02.491.203.385'], ['G02.111.263', 'G03.328'], ['G02.380'], ['D12.776.543'], ['D02.691.850'], ['D08.811.277.040.600'], ['B03.440.400.425.708.733.650', 'B03.660.050.755.750.733.650'], ['G02.805'], ['D02.886.489']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Frequency of thrombolytic therapy in patients with acute ischemic stroke and the risk of in-hospital mortality: the German Stroke Registers Study Group. | BACKGROUND AND PURPOSE: There is little information about early outcome after intravenous application of tissue-type plasminogen activator (tPA) for stroke patients treated in community-based settings. We investigated the association between tPA therapy and in-hospital mortality in a pooled analysis of German stroke re... | ['Adult', 'Aged', 'Atrial Fibrillation', 'Brain Ischemia', 'Case-Control Studies', 'Cohort Studies', 'Comorbidity', 'Diabetes Mellitus', 'Drug Evaluation', 'Female', 'Fibrinolytic Agents', 'Germany', 'Hospital Departments', 'Hospital Mortality', 'Humans', 'Hypertension', 'Logistic Models', 'Male', 'Middle Aged', 'Nervo... | 12,663,875 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Long-term sequelae of deep venous thrombosis of the legs. Experience with mesoglycan]. | Ninety consecutive patients, affected by venographically proven deep-vein thrombosis (DVT) of the lower limbs, were given full-dose heparin followed by oral anticoagulants for 12 weeks, and then selected randomly to receive, for one year, either mesoglycan (72 mg/day orally) or placebo with a double-blind protocol. All... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Glycosaminoglycans', 'Humans', 'Male', 'Middle Aged', 'Patient Compliance', 'Prospective Studies', 'Recurrence', 'Thrombophlebitis'] | 2,535,067 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D09.698.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['E05.318.372.500.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[High pressure injection injuries of the hand with surfacer]. | The most commonly injected materials in high-pressure injection injury to the hand include paint, automotive grease, solvents and diesel oil. High-pressure injection injuries are a frequently mismanaged problem, as they are often not recognized and treated early, which may result in a compromised function of the hand o... | ['Accidents, Occupational', 'Calcium Carbonate', 'Foreign Bodies', 'Hand Injuries', 'Humans', 'Magnesium', 'Male', 'Middle Aged', 'Radiography', 'Reoperation', 'Soft Tissue Injuries', 'Solvents', 'Talc', 'Wounds, Penetrating'] | 11,490,958 | [['N06.850.135.240'], ['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['C26.392'], ['C26.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['M01.060.116.630'], ['E01.370.350.700'], ['E04.690'], ['C26.808'], ['D27.720.844'], ['D01.524.500.850', 'D01... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A high-throughput comparison of recombinant gene expression parameters for E. coli-mediated gene transfer to P388D1 macrophage cells. | Escherichia coli strain BL21(DE3) was tested as a delivery vector for gene transfer to a murine P388D1 macrophage cell line using a 96-well high-throughput assay. Five recombinant strains of E. coli were compared to identify the effect recombinant listeriolysin O (LLO) and associated gene expression parameters had on f... | ['Animals', 'Bacterial Toxins', 'Escherichia coli', 'Escherichia coli Proteins', 'Gene Transfer Techniques', 'Genes, Reporter', 'Genetic Vectors', 'Heat-Shock Proteins', 'Hemolysin Proteins', 'Luciferases', 'Luminescent Measurements', 'Macrophages', 'Mice', 'Recombinant Proteins'] | 18,694,790 | [['B01.050'], ['D23.946.123'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['E05.393.350'], ['G05.360.340.024.340.435'], ['G05.360.337'], ['D12.776.580.216'], ['D12.776.543.695.444'], ['D08.811.682.517', 'D12.776.532.510'], ['E05.196.712.516'], ['A11.329.372', 'A11.627.482', 'A11.733.39... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Initial tests with a new cardiac assist device. | Before, during, and after cardiac intervention, there is occasionally a need for circulatory support because of hemodynamic deterioration. For this purpose, a new minimally invasive cardiac assist device has been developed, and an early prototype has been studied in a bench test and in three pigs. The pump is a cathete... | ['Animals', 'Heart-Assist Devices', 'Hemodynamics', 'Swine'] | 10,445,738 | [['B01.050'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['G09.330.380'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Obesity, hypertension, carbohydrate disorders and the risk of chronic diseases. Is there any epidemiological evidence for integrated prevention programmes? | The major cause of coronary heart disease, hypertension, non-insulin-dependent diabetes and obesity in adults in developed countries appears to be the result of risk factors that are introduced by way of their life-styles. Many developing countries are also noting increases in morbidity and mortality from these disease... | ['Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Diet', 'Female', 'Glucose', 'Humans', 'Hypertension', 'Life Style', 'Male', 'Obesity', 'Physical Exertion', 'Risk', 'Smoking'] | 3,747,912 | [['C14'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203.650.240'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['F01.829.458'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['G11.427.683'], ['E05.318.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The remarkable rise in life expectancy and how it will affect medicine]. | Life expectancy has increased at a steady pace in industrialized countries over the last 160 years. A slowdown is not evident: Since 1950 the number of people celebrating their 100th birthdays has at least doubled each decade. This increase in survival is the result of economic developments, social improvements and adv... | ['Aged', 'Aged, 80 and over', 'Aging', 'Forecasting', 'Germany', 'Humans', 'Life Expectancy', 'Longevity', 'Mortality', 'Prognosis'] | 15,887,070 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['I01.320'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.450', 'N01.224.935.464', 'N06.850.505.400.975.450', 'N06.850.520.308.985.450'], ['G07.345.124.519', 'G07.540'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[The eyespots of the oncomiracidium of Euzetrema knoepffleri (Monogenea): ultrastructure and evolution during the life-cycle (author's transl)]. | Euzetrema knoepffleri (Monogenea, Monopisthocotylea) is a parasite of the urinary bladder of Euproctus montanus (Amphibia, Urodela). The eyespots of the oncomiracidium of E. knoepffleri are rhabdomeric; each anterior pigmented cell has one rhabdomere, each posterior pigmented cell has two rhabdomeres. This pattern is q... | ['Animals', 'Cell Nucleus', 'Cytoplasmic Granules', 'Desmosomes', 'Ecology', 'Eye', 'Larva', 'Lens, Crystalline', 'Light', 'Locomotion', 'Mitochondria', 'Pigments, Biological', 'Trematoda'] | 1,146,380 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['A11.284.149.165.420.297'], ['H01.158.273.248', 'H01.277.249'], ['A01.456.505.420', 'A09.371'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A09.371.060.500'], ['G01.358.500.505.650', 'G01... | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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