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Deoxyribonuclease activity in Selenomonas ruminantium, Streptococcus bovis, and Bacteroides ovatus. | Six Selenomonas ruminantium strains (132c, JW13, SRK1, 179f, 5521c1, and 5934e), Streptococcus bovis JB1, and Bacteroides ovatus V975 were examined for nuclease activity as well as the ability to utilize nucleic acids, ribose, and 2-deoxyribose. Nuclease activity was detected in sonicated cells and culture supernatants... | ['Animals', 'Bacteroides', 'Deoxyribonucleases', 'Deoxyribonucleosides', 'Deoxyribose', 'Nucleic Acids', 'Ribose', 'Ruminants', 'Selenomonas', 'Streptococcus bovis'] | 10,915,204 | [['B01.050'], ['B03.440.080.094.152', 'B03.440.425.410.194.152'], ['D08.811.277.352.335'], ['D13.570.230'], ['D09.254.330'], ['D13.444'], ['D09.947.875.627.651'], ['B01.050.150.900.649.313.500.380'], ['B03.440.425.410.800.877'], ['B03.353.750.737.872.150', 'B03.510.400.800.872.150', 'B03.510.550.737.872.150']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnosis of Carrion's disease by direct blood PCR in thin blood smear negative samples. | Bartonella bacilliformis is the etiologic agent of Carrion's disease. This disease has two well established phases, the most relevant being the so called Oroya Fever, in which B. bacilliformis infect the erythrocytes resulting in severe anemia and transient immunosuppression, with a high lethality in the absence of ade... | ['Adolescent', 'Adult', 'Bartonella', 'Bartonella Infections', 'Child', 'Female', 'Geography', 'Humans', 'Male', 'Middle Aged', 'Peru', 'Polymerase Chain Reaction', 'Young Adult'] | 24,651,298 | [['M01.060.057'], ['M01.060.116'], ['B03.440.090.100', 'B03.660.050.030.040'], ['C01.150.252.400.126.100'], ['M01.060.406'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.107.757.702'], ['E05.393.620.500'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
Factors that Predict an Intern's First ABSITE Score are Known by September. | BACKGROUND: Previous studies offer conflicting relevance of a variety of factors to predict resident performance on the The American Board of Surgery In-Training Exam (ABSITE). With numerous stellar applicants scoring poorly on their first ABSITE, we sought to identify key factors that might allow us to tailor pre-empt... | ['Clinical Competence', 'Cohort Studies', 'Forecasting', 'General Surgery', 'Internship and Residency', 'Specialty Boards', 'Time Factors', 'United States'] | 30,245,062 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I01.320'], ['H02.403.810.300'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['N03.706.110.120.580', 'N05.700.200.190.750'], ['G01.910.857'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Cost-effectiveness evaluation of glucosamine for osteoarthritis based on simulation of individual patient data obtained from aggregated data in published studies. | BACKGROUND: The economic evaluation of treatments usually requires access to individual patient data, which is difficult to obtain. Moreover, in osteoarthritis, health utility scores are unavailable and can be assessed only using a validated equation model based on various clinical data. We aimed to develop and validat... | ['Adult', 'Cost-Benefit Analysis', 'Glucosamine', 'Humans', 'Male', 'Models, Economic', 'Osteoarthritis', 'Quality-Adjusted Life Years'] | 30,746,645 | [['M01.060.116'], ['N03.219.151.125'], ['D09.067.342.531'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.600', 'E05.599.835.890', 'N05.715.360.750.530.500', 'N06.850.520.830.500.600'], ['C05.550.114.606', 'C05.799.613'], ['E05.318.740.100.500.700', 'N01.224.935.530.700']] | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas. | Previous studies have suggested that surface components of papillary thyroid carcinoma (PTC) cells may be aberrantly glycanated, but the precise nature of these molecules has not been unveiled nor documented to be of clinical relevance. A monoclonal antibody was raised against a unique keratan sulfate (KS) determinant ... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Carcinoma, Papillary', 'Epitopes', 'Female', 'Humans', 'Keratan Sulfate', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Protein Isoforms', 'Proteome', 'Spectrometry, Mass, Electrospray Ionization', 'Thyroglobulin', 'Thyroid Gland', 'Thyroid Neop... | 12,819,023 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['D23.050.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.550'], ['B01.050.150.900.649.313.992.63... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of various mouthwashes on the levels of interleukin-2 and interferon-gamma in chronic gingivitis. | The aim of this double blind study was to evaluate the effect of various mouthwashes: Chlorhexidine, Essential oil, Azadirachta indica (Neem) extract, and Povidone iodine on gingival tissue interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) levels in patients with chronic gingivitis. A total of 8O patients (42 boys,... | ['Adolescent', 'Adult', 'Anti-Infective Agents, Local', 'Child', 'Chlorhexidine', 'Chronic Disease', 'Dental Care for Children', 'Dental Plaque', 'Dental Plaque Index', 'Double-Blind Method', 'Female', 'Gingiva', 'Gingivitis', 'Glycerides', 'Humans', 'Interferon-gamma', 'Interleukin-2', 'Male', 'Mouthwashes', 'Oils, Vo... | 18,389,675 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.187'], ['M01.060.406'], ['D02.078.370.141.100'], ['C23.550.291.500'], ['E06.170.152', 'N02.421.240.190.215'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
HFE mutations modulate the effect of iron on serum hepcidin-25 in chronic hemodialysis patients. | BACKGROUND AND OBJECTIVES: Increased serum hepcidin has been reported in patients receiving chronic hemodialysis, and hypothesized to contribute to the alterations of iron metabolism of end-stage renal disease. However, no quantitative assessment is available to date; the clinical determinants are still under definitio... | ['Adult', 'Aged', 'Anemia', 'Antimicrobial Cationic Peptides', 'Biomarkers', 'C-Reactive Protein', 'Case-Control Studies', 'Erythropoiesis', 'Female', 'Ferritins', 'Genotype', 'Hemochromatosis Protein', 'Hepcidins', 'Histocompatibility Antigens Class I', 'Humans', 'Inflammation', 'Iron', 'Kidney Failure, Chronic', 'Mal... | 19,541,813 | [['M01.060.116'], ['M01.060.116.100'], ['C15.378.071'], ['D12.644.050', 'D12.776.543.695.054'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G04.152.825.414', 'G09.188.343.414'], ['D12.776.157.427.249', '... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Barriers to participation in industry-sponsored clinical trials in pediatric type 2 diabetes. | BACKGROUND: The rapid emergence of type 2 diabetes (T2D) in the pediatric population has left pediatric endocrinologists with limited artillery in terms of management. While multiple medications are available for adults, Food and Drug Administration (FDA)-approved medications in children are limited to only metformin a... | ['Adolescent', 'Attitude of Health Personnel', 'Child', 'Diabetes Mellitus, Type 2', 'Drug Approval', 'Drug Industry', 'Drugs, Investigational', 'Endocrinology', 'Humans', 'Hyperglycemia', 'Hypoglycemia', 'Hypoglycemic Agents', 'Internet', 'Needs Assessment', 'Patient Selection', 'Pediatrics', 'Randomized Controlled Tr... | 27,807,915 | [['M01.060.057'], ['F01.100.050', 'N05.300.100'], ['M01.060.406'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['J01.576.655.750'], ['D26.371'], ['H01.158.782.323', 'H02.403.429.323'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['C18.452.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Disciplines and Occupa... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
[Radiation therapy for human renal cell carcinoma transplantable to the nude mice]. | Efficacy of radiation therapy was studied using human renal cell carcinoma strain (AM-RC-3) implantable in nude mice. Cobalt 60 gamma-ray was used dosage of 5 Gy, 10 Gy, 15 Gy and 20 Gy in single, localized exposures of subcutaneously implanted tumors of the lower right femoral region. Therapeutic efficacy was determin... | ['Animals', 'Carcinoma, Renal Cell', 'Dose-Response Relationship, Radiation', 'Humans', 'Kidney Neoplasms', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'Radiotherapy Dosage'] | 2,212,831 | [['B01.050'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Contribution of extrafibrillar matrix to the mechanical behavior of bone using a novel cohesive finite element model. | The mechanical behavior of bone is determined at all hierarchical levels, including lamellae (the basic building block of bone) that are comprised of mineralized collagen fibrils and extrafibrillar matrix. The mechanical behavior of mineralized collagen fibrils has been investigated intensively using both experimental ... | ['Bone Density', 'Bone Matrix', 'Bone and Bones', 'Collagen', 'Durapatite', 'Finite Element Analysis', 'Humans', 'Stress, Mechanical', 'Synchrotrons'] | 27,592,291 | [['G11.427.100'], ['A10.165.265.166'], ['A02.835.232', 'A10.165.265'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The appropriate use of opiates in chronic pain. | Chronic pain is a common but undertreated health problem in the United States. Opioids are effective for moderate-to-severe chronic pain, but these drugs must be used with care due to the risks for overdose and addiction. When initiating opioid treatment, physicians should perform a complete patient history, physical e... | ['Analgesics, Opioid', 'Chronic Pain', 'Humans', 'Opioid-Related Disorders'] | 22,967,785 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['C23.888.592.612.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.775.643.500', 'F03.900.647.500']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-performance liquid chromatographic separation of racemic and diastereomeric mixtures of 2,4-pentadienoate-iron tricarbonyl derivatives. | beta-Cyclodextrin chiral stationary phase facilitates the chiral separation of the (+/-)-methyl-5-formyl-2,4-pentadienoate-iron tricarbonyl (1) racemic mixture. The separation of oxazolidine derivatives 2 and 3 diastereomers were achieved with a C18 column but the compounds underwent in-column hydrolysis to give (-)- a... | ['Chromatography, High Pressure Liquid', 'Cyclodextrins', 'Fatty Acids, Unsaturated', 'Ferric Compounds', 'Indicators and Reagents', 'Stereoisomerism'] | 1,885,684 | [['E05.196.181.400.300'], ['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['D10.251.355'], ['D01.490.100'], ['D27.720.470.410'], ['G02.607.445.682']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis of the verbal reaction behavior of parents in parent-child interactions as a method of diagnosing change in parent training using the Rorschach test]. | The study was performed to found to what extent parents use the ability to verbalize their own feelings and the emotional status of their children that they received during training courses in actual family interaction situations. The Rorschach and Behn-Rohrschach tests were used to simulate family interactions, each f... | ['Child', 'Child Behavior Disorders', 'Child Rearing', 'Humans', 'Parent-Child Relations', 'Parents', 'Rorschach Test', 'Verbal Behavior'] | 6,657,808 | [['M01.060.406'], ['F03.625.141'], ['F01.318'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F04.711.647.622.341.736'], ['F01.145.209.908']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Mediastinal masses masquerading as common respiratory conditions of childhood: a case series. | INTRODUCTION: Leukaemia and lymphoma may present with symptoms and signs mimicking common respiratory conditions of childhood such as asthma or croup. The UK National Institute for Clinical Excellence guidelines for referral for suspected cancer state that "the primary healthcare professional should be ready to review ... | ['Adolescent', 'Asthma', 'Child', 'Croup', 'Diagnosis, Differential', 'Early Diagnosis', 'Female', 'Humans', 'Lymphoma', 'Male', 'Mediastinal Neoplasms', 'Practice Guidelines as Topic', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Radiography', 'Respiratory Tract Diseases'] | 19,205,733 | [['M01.060.057'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['C08.360.535.365', 'C09.400.535.365'], ['E01.171'], ['E01.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['C04.588.894.479', 'C08.846.187.580'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Circulating tumor markers in the monitoring of gynecologic malignancies. | Plasma from 262 patients with gynecologic malignancies was assayed for levels of circulating tumor markers (CA 125, LSA [lipid associated sialic acid in plasma, LASA-P (Dianon Systems, Inc., Stratford, CT )], Ca 19-9, and carcinoembryonic antigen [CEA]) and correlated with the patients' clinical status. In the patients... | ['Antibodies, Monoclonal', 'Antigens, Neoplasm', 'Carcinoembryonic Antigen', 'Endometrium', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Neoplasm Recurrence, Local', 'Ovarian Neoplasms', 'Precancerous Conditions', 'Prognosis', 'Uterine Cervical Neoplasms', 'Uterine Neoplasms'] | 3,594,371 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.285'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['A05.360.319.679.490'], ['C04.588.945.418', 'C13.351.937.418'], ['B01.050.150.900.649.313... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of allostatic load with health-related quality of life in patients with arterial hypertension: a cross-sectional analysis. | AIMS OF THE STUDY: Allostatic load (AL), as a marker of cumulative stress, is associated with higher morbidity and mortality, and reduced health-related quality of life (HrQoL) in healthy adults. In patients with hypertension, AL and its association with HrQoL have not been investigated. Therefore, this study aimed to ... | ['Adaptation, Psychological', 'Aged', 'Aged, 80 and over', 'Allostasis', 'Blood Pressure', 'Cohort Studies', 'Comorbidity', 'Cross-Sectional Studies', 'Female', 'Heart Rate', 'Humans', 'Hypertension', 'Life Style', 'Male', 'Mental Health', 'Middle Aged', 'Quality of Life', 'Socioeconomic Factors', 'Surveys and Question... | 30,552,856 | [['F01.058'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G16.012.500.274'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Serum insulin and glucose response to graded exercise in adults. Part I: the influence of fitness status. | The effect of acute exercise upon serum immunoreactive insulin levels (IRI) and serum glucose concentrations (GC) was studied in groups of middle-aged men of contrasting physical fitness status. Two groups of subjects, one active and one sedentary (both N = 11, mean age 44 years), performed a graded cycle ergometer exe... | ['Adult', 'Blood Glucose', 'Blood Pressure', 'Body Weight', 'Humans', 'Insulin', 'Male', 'Middle Aged', 'Physical Exertion', 'Physical Fitness'] | 687,888 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Addictive agents and intracranial stimulation (ICS): novel antagonists and agonists of morphine and pressing for ICS. | Rats fixed with chronically indwelling bipolar electrodes pressed for intracranial stimulation (ICS) of the lateral hypothalamus during daily sessions. The effects of two antagonists of morphine (Win 44,441 and naloxone) were then assessed. Naloxone (10 mg/kg) produced its characteristic reduction in pressing. Win 44, ... | ['Animals', 'Azocines', 'Brain', 'Electric Stimulation', 'Hypothalamic Area, Lateral', 'Male', 'Morphine', 'Naloxone', 'Rats', 'Rats, Inbred Strains', 'Self Stimulation'] | 6,856,650 | [['B01.050'], ['D03.383.113'], ['A08.186.211'], ['E05.723.402'], ['A08.186.211.180.497.300', 'A08.186.211.200.317.357.300'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04.615.723.795.706'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetic interaction between the hepatitis C virus protease inhibitor boceprevir and cyclosporine and tacrolimus in healthy volunteers. | UNLABELLED: The hepatitis C virus protease inhibitor boceprevir is a strong inhibitor of cytochrome P450 3A4 and 3A5 (CYP3A4/5). Cyclosporine and tacrolimus are calcineurin inhibitor immunosuppressants used to prevent organ rejection after liver transplantation; both are substrates of CYP3A4. This two-part pharmacokine... | ['Adult', 'Antiviral Agents', 'Area Under Curve', 'Cyclosporine', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Female', 'Hepatitis C', 'Humans', 'Immunosuppressive Agents', 'Male', 'Proline', 'Protease Inhibitors', 'Tacrolimus', 'Young Adult'] | 22,576,324 | [['M01.060.116'], ['D27.505.954.122.388'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Voronoi-based spatial analysis reveals selective interneuron changes in the cortex of FALS mice. | The neurodegenerative disease amyotrophic lateral sclerosis affects lower motoneurons and corticospinal cells. Mice expressing human mutant superoxide dismutase (SOD)1 provide widely investigated models of the familial form of disease, but information on cortical changes in these mice is still limited. We here analyzed... | ['Age Factors', 'Amyotrophic Lateral Sclerosis', 'Analysis of Variance', 'Animals', 'Behavior, Animal', 'Cerebral Cortex', 'Disease Models, Animal', 'Humans', 'Interneurons', 'Mice', 'Mice, Transgenic', 'Parvalbumins', 'Superoxide Dismutase'] | 18,926,824 | [['N05.715.350.075', 'N06.850.490.250'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['F01.145.113'], ['A08.186.211.200.885.287.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], [... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Diverticula of the terminal ileum. | The radiological appearances are described of acquired ileal diverticula, seen in four patients as an incidental finding. All the diverticula were small and sited on the mesenteric border of the terminal ileum. Solitary diverticula were seen in three patients and in the fourth case there were three diverticula. | ['Adult', 'Diverticulum', 'Female', 'Humans', 'Ileal Diseases', 'Male', 'Middle Aged', 'Radiography'] | 2,494,012 | [['M01.060.116'], ['C06.405.205.282.750', 'C23.300.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.420'], ['M01.060.116.630'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
OMNI scale perceived exertion at ventilatory breakpoint in children: response normalized. | PURPOSE: The Children's OMNI Scale of Perceived Exertion was used to identify a response normalized rating of perceived exertion (RPE)-Overall, RPE-Legs, and RPE-Chest that corresponds to the ventilatory breakpoint (Vpt) in 8- to 12-yr-old female and male children.METHODS: Subjects were a priori stratified into two fit... | ['Anaerobic Threshold', 'Analysis of Variance', 'Child', 'Exercise Test', 'Female', 'Heart Rate', 'Humans', 'Leg', 'Male', 'Oxygen Consumption', 'Physical Exertion', 'Physical Fitness', 'Reference Values', 'Reproducibility of Results', 'Sex Factors', 'Thorax'] | 11,689,748 | [['G03.680.110', 'G11.427.680.134'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['G03.680'], ['G11.427... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Clinical applications of The Cancer Genome Atlas project (TCGA) for squamous cell lung carcinoma. | Very little progress has been made in the treatment of patients with metastatic squamous cell lung cancer over the past 2 decades. Identification of novel molecular alterations for targeted therapies is necessary to improve outcomes. Advances in genomic technology have now made it possible to analyze the genomic landsc... | ['Antineoplastic Agents', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'Databases, Genetic', 'Drug Design', 'Genetic Predisposition to Disease', 'Genome, Human', 'Genomics', 'Humans', 'Lung Neoplasms', 'Molecular Targeted Therapy', 'Patient Selection', 'Phenotype', 'Precision Medicine', 'Prognosis', 'Signal Transdu... | 24,282,988 | [['D27.505.954.248'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.360.340.350'], ['H01.158.273.180.350', 'H01.158.273.343.350'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Human Herpesvirus 8-Unrelated Primary Effusion Lymphoma-Like Lymphoma in an Elderly Korean Patient with a Good Response to Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone. | Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin's lymphoma arising from a B-cell lineage characterized by the formation of malignant effusion in body cavities without evidence of a detectable tumor. The effusion contains tumor cells universally infected with human herpesvirus 8 (HHV8), which is the critic... | ['Age Factors', 'Aged', 'Antibodies, Monoclonal, Murine-Derived', 'Antineoplastic Combined Chemotherapy Protocols', 'Biomarkers', 'Biopsy', 'Cyclophosphamide', 'Doxorubicin', 'Herpesviridae Infections', 'Herpesvirus 8, Human', 'Humans', 'Lymphoma, Primary Effusion', 'Male', 'Multimodal Imaging', 'Prednisone', 'Remissio... | 27,283,030 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D23.101'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074'... | ['Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Volume Change of Pedicled Latissimus Dorsi Muscle Flap after Partial Breast Reconstruction. | INTRODUCTION: Despite successful breast reconstruction with oversized latissimus dorsi muscle flap after breast-conserving surgery for breast cancer, esthetic problems continue to exist due to flap shrinkage. The purpose of this study was to evaluate the objective volume change of pedicled latissimus dorsi muscle flap... | ['Adult', 'Breast Neoplasms', 'Esthetics', 'Female', 'Humans', 'Mammaplasty', 'Mastectomy', 'Middle Aged', 'Radiotherapy, Adjuvant', 'Superficial Back Muscles', 'Surgical Flaps', 'Treatment Outcome'] | 30,099,736 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['F02.463.785.477', 'K01.752.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['E04.466'], ['M01.060.116.630'], ['E02.186.775', 'E02.815.600'], ['A02.633.567.175.875'], ['A10.850.710', 'E07.862.710'], ['E01.789.800', 'N04.761.5... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Successful mobilization with AMD3100 and filgrastim with engraftment of autologous peripheral blood stem cells in a heavily pretreated pediatric patient with recurrent Burkitt lymphoma. | The authors report a case of a 13-year-old female with recurrent Burkitt lymphoma who was heavily pretreated with chemotherapy. During chemotherapy for relapse, she developed serious aspergillus infection of the palate and sinuses. Despite 10 microg/kg of filgrastim for 5 days, peripheral blood CD34(+) cells remained <... | ['Adolescent', 'Antineoplastic Combined Chemotherapy Protocols', 'Burkitt Lymphoma', 'Female', 'Filgrastim', 'Granulocyte Colony-Stimulating Factor', 'Hematopoietic Stem Cell Mobilization', 'Heterocyclic Compounds', 'Humans', 'Peripheral Blood Stem Cell Transplantation', 'Recombinant Proteins', 'Recurrence', 'Treatment... | 20,201,695 | [['M01.060.057'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['D12.644.276.374.410.240.350.500', 'D12.776.395.240.200.500', 'D12.776.467.374.410.240.350.500', 'D23... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Duplex Doppler ultrasound of hepatic Schistosomiasis japonica: a study of 47 patients. | This study describes the ultrasound (US) appearances of the liver with hepatic schistosomiasis japonica (HSJ), and studies the portal hemodynamics in 47 patients with HSJ using duplex Doppler US over a period of 15 years. All patients but two were Chinese war veterans seen in Taiwan about 35-55 years after their presum... | ['Aged', 'Animals', 'Biopsy', 'Blood Flow Velocity', 'Humans', 'Laser-Doppler Flowmetry', 'Liver', 'Liver Diseases, Parasitic', 'Male', 'Middle Aged', 'Portal Vein', 'Regional Blood Flow', 'Schistosoma japonicum', 'Schistosomiasis japonica', 'Ultrasonography, Doppler, Duplex'] | 12,556,142 | [['M01.060.116.100'], ['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.370.475', 'E05.830.500'], ['A03.620'], ... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Efficacy and safety of semicircular canal occlusion for intractable horizontal semicircular benign paroxysmal positional vertigo. | BACKGROUND: Some studies have suggested that semicircular canal occlusion is effective and safe for treating intractable posterior semicircular benign paroxysmal positional vertigo (PSC-BPPV), and adverse effects of canal occlusions for intractable horizontal semicircular BPPV (HSC-BPPV) were rarely reported. The aim o... | ['Aged', 'Benign Paroxysmal Positional Vertigo', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Otologic Surgical Procedures', 'Posture', 'Retrospective Studies', 'Semicircular Canals', 'Time Factors', 'Treatment Outcome'] | 25,358,608 | [['M01.060.116.100'], ['C09.218.568.900.883.500', 'C10.597.951.500', 'C23.888.592.958.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.580.450'], ['G11.427.695'], ['E05.318.372.500.500.500', 'E05... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Boundary Element Method for Reconstructing Absorption and Diffusion Coefficients of Biological Tissues in DOT/MicroCT Imaging. | The functional information, the absorption and diffusion coefficients, as well as the structural information of biological tissues can be provided by the DOT(Diffuse Optical Tomograph)/MicroCT. In this paper, we use boundary element method to calculate the forward problem of DOT based on the structure prior given by th... | ['Algorithms', 'Computer Simulation', 'Image Interpretation, Computer-Assisted', 'Numerical Analysis, Computer-Assisted', 'Predictive Value of Tests', 'Reproducibility of Results', 'Tomography, Optical', 'X-Ray Microtomography'] | 27,526,172 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.224.680.700'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E01.370.350.589.249', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Age of diphtheria, tetanus, and pertussis immunization of special care nursery graduates. | Diphtheria, tetanus, and pertussis (DTP) immunization data were collected on 103 special care nursery graduates in our neonatal follow-up clinic to determine whether DTP immunization schedules were significantly delayed relative to recommendations of the American Academy of Pediatrics (2, 4, and 6 months for DTP 1, 2, ... | ['Birth Weight', 'Diphtheria Toxoid', 'Diphtheria-Tetanus-Pertussis Vaccine', 'Drug Combinations', 'Humans', 'Immunization Schedule', 'Infant', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Intensive Care Units, Neonatal', 'Pertussis Vaccine', 'Tetanus Toxoid', 'Time Factors'] | 3,485,786 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['D20.215.894.691.263'], ['D20.215.894.135.535.300', 'D20.215.894.691.263.300', 'D20.215.894.691.824.300', 'D20.215.894.815.300'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regional and Racial Inequality in Infectious Disease Mortality in U.S. Cities, 1900-1948. | In the first half of the twentieth century, the rate of death from infectious disease in the United States fell precipitously. Although this decline is well-known and well-documented, there is surprisingly little evidence about whether it took place uniformly across the regions of the United States. We use data on infe... | ['African Americans', 'Cities', 'Communicable Diseases', 'European Continental Ancestry Group', 'Female', 'History, 20th Century', 'Humans', 'Influenza Pandemic, 1918-1919', 'Male', 'Residence Characteristics', 'Southeastern United States', 'United States', 'Urban Population'] | 31,197,611 | [['M01.686.508.100.100', 'M01.686.754.100'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['C01.221', 'C23.550.291.531'], ['M01.686.508.400'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.400.504.968.450'], ['N01.224.791', 'N06.850.505.400.800'], ['Z01.107.567.875.750'], ['Z01.107.567.8... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Humanities [K]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A comparison of flocked nylon swabs and non-flocked rayon swabs for detection of respiratory bacteria in nasopharyngeal carriage in Australian Indigenous children. | This study compared flocked (nylon) swabs and (non-flocked) rayon swabs for the detection of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in nasopharyngeal samples from 20 enrolled Indigenous children under the age of 6 years living in remote Australian Aboriginal communities, and determin... | ['Australia', 'Carrier State', 'Cellulose', 'Child', 'Child, Preschool', 'Haemophilus influenzae', 'Humans', 'Indigenous Peoples', 'Infant', 'Infant, Newborn', 'Moraxella catarrhalis', 'Nasopharynx', 'Nylons', 'Patient Preference', 'Specimen Handling', 'Streptococcus pneumoniae'] | 30,578,888 | [['Z01.639.100', 'Z01.678.100.373'], ['N06.850.520.169'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['M01.060.406'], ['M01.060.406.448'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.754.254'], ['M01.06... | ['Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
What difference do brain images make in US criminal trials? | One of the early concerns regarding the use of neuroscience data in criminal trials is that even if the brain images are ambiguous or inconclusive, they still might influence a jury in virtue of the fact that they appear easy to understand. By appearing visually simple, even though they are really statistically constru... | ['Brain', 'Criminal Law', 'Criminals', 'Decision Making', 'Expert Testimony', 'Humans', 'Jurisprudence', 'Neuroimaging', 'Philosophy, Medical', 'United States'] | 29,744,995 | [['A08.186.211'], ['I01.198.290', 'I01.880.604.583.100'], ['M01.142'], ['F02.463.785.373'], ['I01.880.604.583.232', 'N03.706.535.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583', 'N03.706.535'], ['E01.370.350.578', 'E01.370.376.537', 'E05.629'], ['K01.752.667'], ['Z01.107.567.875']] | ['Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Renal sinus lipomatosis: differentiation from space-occupying lesion with aid of computed tomography. | Forty-two cases of renal sinus lipomatosis were diagnosed by intravenous urography and nephrotomography. The differential diagnosis from a malignant process necessitated selective renal angiography in 9 cases. With the aid of computed tomography (CT), an invasive technique such as renal angiography appears to be unnece... | ['Aged', 'Female', 'Humans', 'Kidney Neoplasms', 'Lipomatosis', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 7,352,356 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C17.800.463', 'C18.452.584.718'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', '... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biotechnological production of xylitol in a three-phase fluidized bed bioreactor with immobilized yeast cells in Ca-alginate beads. | Cells of Candida guilliermondii entrapped in Ca-alginate beads were used for xylitol production, from concentrated hemicellulose hydrolyzate of sugarcane bagasse, in a fluidized bed bioreactor (FBR). The maximum xylitol concentration 28.9 g xylitol/L was obtained at a high aeration rate of 600 mL/min after 70 h of ferm... | ['Alginates', 'Bioreactors', 'Biotechnology', 'Candida', 'Cell Culture Techniques', 'Cell Proliferation', 'Cells, Immobilized', 'Equipment Design', 'Equipment Failure Analysis', 'Glucuronic Acid', 'Hexuronic Acids', 'Microfluidics', 'Microspheres', 'Xylitol'] | 17,427,994 | [['D09.698.068'], ['E07.115', 'J01.897.120.115'], ['H01.158.550', 'J01.897.120'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.270'], ['E05.320'], ['E05.325.192'], ['D02.241.081.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Inflammatory pseudotumor of the hypopharynx: clinical diagnosis, immunohistochemical findings and treatment of this rare disease. | Inflammatory pseudotumor (IPT) is a rare benign lesion, often imitating a malignant disease. An IPT was found in the sinus piriformis of a 40-year-old male who suffered from dysphagia, globus feeling and a weight loss of 5 kilograms in six months. Neither common infections previously described in combination with IPT s... | ['Adult', 'Granuloma, Plasma Cell', 'Humans', 'Hypopharyngeal Neoplasms', 'Hypopharynx', 'Immunohistochemistry', 'Male', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Weight Loss'] | 19,181,013 | [['M01.060.116'], ['C23.550.382.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.485'], ['A04.623.490', 'A14.724.490'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583'... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Positional relationship between the facial nerve and other structures of the temporal bone. | The quantitative relationships between the position of the mastoid segment of the facial nerve, mastoid pneumatization and the positions of neighbouring structures are undetermined. Using high resolution computed tomography (HRCT), the positions of these structures were measured in 66 normal temporal bones. A new metho... | ['Adult', 'Aged', 'Craniotomy', 'Facial Nerve', 'Female', 'Gender Identity', 'Humans', 'Image Processing, Computer-Assisted', 'Jugular Veins', 'Male', 'Middle Aged', 'Reference Values', 'Temporal Bone', 'Tomography, X-Ray Computed'] | 14,979,946 | [['M01.060.116'], ['M01.060.116.100'], ['E04.525.190'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A07.015.908.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Gonadotrophin responses to oestrogen provocation in women with minimal endometriosis. | The gonadotrophin responses to the negative and positive feedback effects of orally administered ethinyl oestradiol in 12 women with minimal endometriosis were compared with those in six normal women of proven fertility. Basal concentrations of LH, FSH and oestradiol did not differ between the two groups. LH and FSH co... | ['Adult', 'Endometriosis', 'Estradiol', 'Ethinyl Estradiol', 'Female', 'Follicle Stimulating Hormone', 'Humans', 'Luteinizing Hormone'] | 3,123,046 | [['M01.060.116'], ['C13.351.500.163'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D04.210.500.668.651.568.291', 'D06.472.334.851.437.968.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.322.576... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration. | Sirtuins are an evolutionarily conserved family of NAD(+)-dependent protein deacetylases that function in the regulation of gene transcription, cellular metabolism, and aging. Their activity requires the maintenance of an adequate intracellular NAD(+) concentration through the combined action of NAD(+) biosynthesis and... | ['DNA, Fungal', 'DNA, Ribosomal', 'Gene Silencing', 'Genetic Loci', 'NAD', 'Niacinamide', 'Nicotinamidase', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Silent Information Regulator Proteins, Saccharomyces cerevisiae', 'Sirtuin 2'] | 22,539,348 | [['D13.444.308.300'], ['D13.444.308.475'], ['G05.308.203.374'], ['G05.360.340.024.380'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['D03.066.515.530', 'D03.383.725.547.530'], ['D08.811.277.087.610'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.75... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis of alpha-amino acids via asymmetric phase transfer-catalyzed alkylation of achiral nickel(II) complexes of glycine-derived Schiff bases. | Achiral, diamagnetic Ni(II) complexes 1 and 3 have been synthesized from Ni(II) salts and the Schiff bases, generated from glycine and PBP (7) and PBA (11), respectively, in MeONa/MeOH solutions. The requisite carbonyl-derivatizing agents pyridine-2-carboxylic acid(2-benzoyl-phenyl)-amide 7 (PBP) and pyridine-2-carboxy... | ['Alkylation', 'Amino Acids', 'Crystallography, X-Ray', 'Glycine', 'Magnetic Resonance Spectroscopy', 'Nickel', 'Organometallic Compounds', 'Schiff Bases', 'Spectrophotometry, Infrared', 'Stereoisomerism'] | 14,558,835 | [['G02.111.035', 'G02.607.094', 'G03.059'], ['D12.125'], ['E05.196.309.742.225'], ['D12.125.481'], ['E05.196.867.519'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['D02.691'], ['D02.491.784'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['G02.607.445.682']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Performance of a propensity score adjustment in longitudinal studies with covariate-dependent representation. | Longitudinal observational studies provide rich opportunities to examine treatment effectiveness during the course of a chronic illness. However, there are threats to the validity of observational inferences. For instance, clinician judgment and self-selection play key roles in treatment assignment. To account for this... | ['Antidepressive Agents', 'Computer Simulation', 'Depression', 'Humans', 'Longitudinal Studies', 'Models, Statistical', 'Propensity Score'] | 22,495,765 | [['D27.505.954.427.700.122'], ['L01.224.160'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.740.600.675', 'N05.7... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A method to measure the degree of control per se in the oral glucose tolerance test. | Using the glucose and insulin values from a 5-hr oral glucose tolerance test, nine quantitative measures have been developed to separate normal, "flat-curve," and non-insulin-dependent diabetic (NIDD) patients. The purpose of these measures is to quantify per se the degree of control operating in glucose homeostasis. A... | ['Adult', 'Blood Glucose', 'Data Interpretation, Statistical', 'Diabetes Mellitus, Type 2', 'Diagnostic Errors', 'Female', 'Glucose Tolerance Test', 'Homeostasis', 'Humans', 'Insulin', 'Male', 'Middle Aged'] | 2,673,656 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C18.452.394.750.149', 'C19.246.300'], ['E01.354', 'N02.421.450.280'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['G07.410'], ['B01.05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[IFOBT-positive gastric cancer]. | Among 888 patients who underwent operation or endoscopic resection for gastric cancer (1994-1998), 75 patients, who had no colorectal disease or only small polyps 5 mm or less in diameter, were positive on the immunologic fecal occult blood test (IFOBT) (the positive group). They are compared with the other 813 patient... | ['Female', 'Hemagglutination Tests', 'Humans', 'Intestinal Polyps', 'Male', 'Middle Aged', 'Occult Blood', 'Stomach Neoplasms'] | 10,879,080 | [['E01.370.225.812.735.050.375', 'E05.200.812.735.050.375', 'E05.478.594.760.050.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.825.411'], ['M01.060.116.630'], ['E01.370.225.925', 'E05.200.925'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls. | Alterations in the gut microbiome have been implicated in the pathogenesis of several immune-mediated inflammatory diseases such as psoriatic arthritis. This work aimed to characterize the gut microbial signature of patients with active psoriasis as compared with age-, body mass index- and comorbidity-matched non-psori... | ['Adult', 'Bacteria', 'Case-Control Studies', 'Cohort Studies', 'DNA, Bacterial', 'Feces', 'Female', 'Gastrointestinal Microbiome', 'Humans', 'Intestinal Mucosa', 'Israel', 'Lipopolysaccharides', 'Male', 'Middle Aged', 'Psoriasis', 'RNA, Ribosomal, 16S'] | 31,141,234 | [['M01.060.116'], ['B03'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D13.444.308.212'], ['A12.459'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['B01.050.150.900.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ciprofloxacin-protected gold nanoparticles. | The antibacterial drug ciprofloxacin (cfH) has been used to protect gold nanoparticles of two different mean diameters, 4 and 20 nm. The protection is complete with about 65 and 585 cfH molecules covering 4 and 15 nm particles, respectively. The nature of binding has been investigated by several analytical techniques. ... | ['Adsorption', 'Anti-Bacterial Agents', 'Ciprofloxacin', 'Delayed-Action Preparations', 'Drug Carriers', 'Gold', 'Microscopy, Electron, Transmission', 'Nanostructures'] | 15,801,462 | [['G01.030', 'G02.020'], ['D27.505.954.122.085'], ['D03.633.100.810.835.322.186'], ['D26.255.210', 'E02.319.300.253'], ['D26.255.260', 'E02.319.300.380'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['J01.637.512']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Playing one's cards face up in analysis: an approach to the problem of self-disclosure. | A policy of consistent willingness on the analyst's part to make his or her own views explicitly available to the patient is discussed and illustrated by clinical vignettes. Playing one's cards face up is contrasted with contemporary conceptions of selective self-disclosure by the analyst, especially with respect to th... | ['Female', 'Humans', 'Physician-Patient Relations', 'Psychoanalysis', 'Psychotherapeutic Processes', 'Truth Disclosure'] | 10,618,819 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F04.096.544.779'], ['F04.754.720'], ['F01.829.401.046.800', 'I01.880.604.583.080.134.800']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Alternate technic for operative cholangiography. | Occasionally the cystic duct cannot be cannulated for cholangiography. A technic of cholangiography via a fine needle is described that allows similar injection of dye. The needle must be secured to prevent dislodgement during the procedure. | ['Cholangiography', 'Common Bile Duct', 'Humans', 'Needles'] | 1,166,926 | [['E01.370.350.700.715.200', 'E01.370.372.200'], ['A03.159.183.079.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.612']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensory innervation of the rat portal vein and the hepatic artery. | Several neuroanatomical and neurophysiological experiments suggest that the hepatic portal vein is not only richly innervated with sympathetic efferents, but also it is an important source of afferent information. By combining retrograde tracing (with True Blue as a marker) and immunological techniques, the cell bodies... | ['Animals', 'Catecholamines', 'Ganglia, Spinal', 'Hepatic Artery', 'Male', 'Portal Vein', 'Rats', 'Spinal Nerves', 'Substance P', 'Sympathetic Nervous System', 'Vagus Nerve'] | 6,205,041 | [['B01.050'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['A07.015.114.407'], ['A07.015.908.670.567'], ['B01.050.150.900.649.313.992.635.505.700'], ['A08.800.800.720'], ['D12.644.276.812.900.866', 'D12.644.400.800.750', 'D12.644.456.800.866', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bone biopsy: indications, techniques, and complications. | Bone biopsy is the gold standard for diagnosing the type and severity of renal osteodystrophy (ROD) in end-stage renal disease (ESRD) patients. In this article we review the indications, techniques, and complications of this minimally invasive procedure. The importance of careful preparation is emphasized. | ['Biopsy, Needle', 'Bone Diseases', 'Bone and Bones', 'Chronic Kidney Disease-Mineral and Bone Disorder', 'Humans'] | 12,926,408 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C05.116'], ['A02.835.232', 'A10.165.265'], ['C05.116.198.816.750', 'C12.777.419.080', 'C13.351.968.419.795', 'C18.452.104.816.750',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of integrins in human gingiva. | The distribution of the alpha 1-alpha 6 subunits of beta 1 integrins was studied by using a panel of monoclonal antibodies in indirect immunofluorescence microscopy. The results showed that the beta 1 subunit was expressed at the cell membrane of basal cells of gingival epithelium, throughout the cells of junctional ep... | ['Adolescent', 'Adult', 'Antibodies, Monoclonal', 'Child', 'Connective Tissue', 'Epithelial Attachment', 'Gingiva', 'Humans', 'Immunohistochemistry', 'Integrins', 'Membrane Proteins', 'Microscopy, Fluorescence', 'Middle Aged'] | 2,250,086 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['M01.060.406'], ['A10.165'], ['A14.549.167.646.374'], ['A14.549.167.646.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Host response to porcine strains of Escherichia coli in a novel pyelonephritis model. | The initial pathology and pathogenesis of pyelonephritis and the influence of different strains of Escherichia coli were investigated in a novel porcine model. Nine female pigs were divided into three groups (A, B and C) and inoculated repeatedly into one renal pelvis with porcine pyelonephritis E. coli strain LK67 (P ... | ['Animals', 'Antigens, CD', 'Disease Models, Animal', 'Escherichia coli', 'Escherichia coli Infections', 'Female', 'Host-Pathogen Interactions', 'Kidney', 'Leukocyte Count', 'Neutrophils', 'Pyelonephritis', 'Species Specificity', 'Specific Pathogen-Free Organisms', 'Swine', 'Swine Diseases', 'Virulence Factors'] | 21,159,351 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['G06.462', 'G16.527.200'], ['A05.810.453'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accuracy of a Radiological Evaluation Method for Thoracic and Lumbar Spinal Curvatures Using Spinous Processes. | OBJECTIVE: The purpose of this study was to assess a radiographic method for spinal curvature evaluation in children, based on spinous processes, and identify its normality limits.METHODS: The sample consisted of 90 radiographic examinations of the spines of children in the sagittal plane. Thoracic and lumbar curvature... | ['Adolescent', 'Age Factors', 'Brazil', 'Child', 'Child, Preschool', 'Cohort Studies', 'Early Diagnosis', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Kyphosis', 'Lordosis', 'Lumbar Vertebrae', 'Male', 'Prospective Studies', 'Sensitivity and Specificity', 'Sex Factors', 'Spinal Curvatures', 'Thoracic Ver... | 29,229,061 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C05.116.900.800.500'], ['C05.116.900.800.75... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Constitutive activation of met kinase in non-small-cell lung carcinomas correlates with anchorage-independent cell survival. | Lung cancer is currently the most frequent cause of cancer death in North America. Hepatocyte growth factor (HGF) and its receptor Met are frequently over-expressed in non-small-cell lung carcinomas (NSCLC), but their potential role in tumor progression is not clearly known. To assess the role of HGF/Met signaling in l... | ['Animals', 'Antibodies, Monoclonal', 'Blotting, Western', 'Carcinoma, Non-Small-Cell Lung', 'Cell Adhesion', 'Cell Survival', 'Chromatography, Affinity', 'DNA, Neoplasm', 'Dogs', 'Enzyme Activation', 'Humans', 'Kidney', 'Lung Neoplasms', 'Paracrine Communication', 'Phosphatidylinositol 3-Kinases', 'Precipitin Tests', ... | 12,210,733 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G04.022'], ['G04.346'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Traditional concepts of mental disorder among Indian psychiatric patients: preliminary report of work in progress. | In a medically pluralistic setting a range of health care providers offer not only different forms of treatment, but different ways of understanding illness. Even within a single tradition, these concepts evolve over time. Chapters in the classical texts of Ayurveda describe varieties of severe mental disorder (unmada)... | ['Attitude to Health', 'Female', 'Homeopathy', 'Humans', 'India', 'Male', 'Medicine, Ayurvedic', 'Medicine, Traditional', 'Mental Disorders', 'Mental Healing', 'Models, Theoretical'] | 3,749,981 | [['F01.100.150', 'N05.300.150'], ['E02.190.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E02.190.488.515', 'I01.076.201.450.654.515'], ['E02.190.488', 'I01.076.201.450.654'], ['F03'], ['E02.190.525.500', 'E02.190.901.500'], ['E05.599']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Production, purification and characterization of the plasminogen activator in teratocarcinoma stem cells induced with sodium butyrate. | Suspension cultures of pluripotent teratocarcinoma cells were induced with sodium butyrate to produce plasminogen activator (PA), generally regarded as a marker enzyme of differentiation of the teratocarcinoma. The induction of plasminogen activator was very efficient, resulting in production of sufficient enzyme to al... | ['Animals', 'Butyrates', 'Butyric Acid', 'Cell Line', 'Cell Transformation, Neoplastic', 'Electrophoresis, Polyacrylamide Gel', 'Embryonal Carcinoma Stem Cells', 'Enzyme Induction', 'Humans', 'Immune Sera', 'Melanoma', 'Mice', 'Neoplastic Stem Cells', 'Plasminogen Activators', 'Plasminogen Inactivators', 'Stem Cells', ... | 6,443,174 | [['B01.050'], ['D02.241.081.114', 'D10.251.400.143'], ['D02.241.081.114.750', 'D10.251.400.143.500'], ['A11.251.210'], ['C04.697.098.500', 'C23.550.727.098.500'], ['E05.196.401.402', 'E05.301.300.319'], ['A11.251.860.590', 'A11.872.650.500', 'A11.872.700.250.500'], ['G05.308.320.200'], ['B01.050.150.900.649.313.988.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stability of bovine insulin. | A stability experiment on purified crystalline bovine insulin showed that it deteriorates at normal refrigeration temperature (5 degrees C) and that storage at -20 degrees C is necessary to ensure stability. Purified insulin degrades by two mechanisms: deamidation and polymerization. Immunochemical potency determinatio... | ['Animals', 'Cattle', 'Drug Stability', 'Insulin', 'Polymers'] | 6,115,900 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.916.330'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D05.750', 'D25.720', 'J01.637.051.720']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Life satisfaction across treatment methods for patients with end-stage renal failure. | After a report which challenged the generally-held view that renal-transplant recipients have a psychological advantage compared with patients who undergo dialysis, we surveyed the quality of life and psychological distress in all patients who were managed by renal transplantation or dialysis at The Royal Newcastle Hos... | ['Female', 'Hemodialysis, Home', 'Humans', 'Internal-External Control', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Life Change Events', 'Male', 'Middle Aged', 'Peritoneal Dialysis, Continuous Ambulatory', 'Personal Satisfaction', 'Quality of Life', 'Renal Dialysis'] | 2,654,590 | [['E02.870.300.300', 'E02.912.800.300', 'N02.421.143.524.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['F01.829.458.410'], ['M01.060.116.630'], ['E02.760.106.500', 'E02.870.300.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Emergency feasibility in medical intensive care unit of extracorporeal life support for refractory cardiac arrest. | OBJECTIVE: To report the feasibility, complications, and outcomes of emergency extracorporeal life support (ECLS) in refractory cardiac arrests in medical intensive care unit (ICU).DESIGN AND SETTING: Prospective cohort study in the medical ICU in a university hospital in collaboration with the cardiosurgical team of a... | ['APACHE', 'Adult', 'Advanced Cardiac Life Support', 'Extracorporeal Membrane Oxygenation', 'Feasibility Studies', 'Female', 'Heart Arrest', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Poisoning', 'Survival Analysis'] | 17,342,517 | [['E05.318.308.980.438.475.365', 'E05.318.308.980.438.475.456.500.250', 'N05.715.360.300.800.438.375.364.500.250', 'N06.850.520.308.980.438.475.364.500.250'], ['M01.060.116'], ['E02.365.647.110.500', 'E02.760.440.028', 'N02.421.585.440.028'], ['E02.880.301', 'E04.292.451'], ['E05.318.372.550', 'E05.337.675', 'N05.715.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Biological and genetic changes in ovine lentivirus strains following passage in isogeneic twin lambs. | Ovine lentivirus (OvLV) strains vary in cytopathogenicity, but the correlation, if any, between viral cytophenotypes and in vivo pathogenicity is poorly understood. To examine this issue and to evaluate changes in OvLV strains following passage in vivo, biological and genetic characteristics of OvLV isolates following ... | ['Animals', 'Base Sequence', 'Cytopathogenic Effect, Viral', 'Genes, env', 'Genetic Variation', 'Molecular Sequence Data', 'Pneumonia, Progressive Interstitial, of Sheep', 'Serial Passage', 'Sheep', 'Twin Studies as Topic', 'Twins, Monozygotic', 'Virus Replication', 'Visna-maedi virus'] | 7,834,396 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['G05.360.340.024.340.364.875.172', 'G05.360.340.358.024.875.172', 'G05.360.340.358.840.500.172'], ['G05.365'], ['L01.453.245.667'], ['C01.925.782.815.616.660', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Simultaneous triple fluorescence detection of mRNA localization, nuclear DNA, and apoptosis in cultured cells using confocal scanning laser microscopy. | We describe a multifluorescence labeling technique for simultaneous detection of mRNA, nuclear DNA, and apoptosis in cultured cells. Digoxigenin-labeled cRNA probes were used to study proto-oncogene expression in rat pleural mesothelial cells undergoing apoptosis following exposure to crocidolite asbestos or hydrogen p... | ['Animals', 'Apoptosis', 'Asbestos, Crocidolite', 'Benzoxazoles', 'Carbocyanines', 'Cell Nucleus', 'Cells, Cultured', 'DNA', 'Fluorescence', 'Fluorescent Dyes', 'In Situ Hybridization, Fluorescence', 'Microscopy, Confocal', 'Proto-Oncogene Proteins c-fos', 'Proto-Oncogene Proteins c-jun', 'Quinolinium Compounds', 'RNA,... | 9,387,922 | [['B01.050'], ['G04.146.954.035'], ['D01.578.725.050.050.100', 'D01.837.725.700.760.070.050.090'], ['D03.633.100.221'], ['D02.455.326.397.300'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['D13.444.308'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D27.720.233.348', 'D27.720.470.410.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe asthma in pediatrics: Outcomes of the implementation of a special health care protocol. | INTRODUCTION: Severe asthma accounts for 5-7% of all asthma cases. The World Health Organization proposed a follow-up protocol to classify cases into severe, treatment-resistant asthma (STRA) or severe, difficult-to-control asthma (SDCA).OBJECTIVE: To analyze the clinical, functional, and therapeutic characteristics of... | ['Adolescent', 'Asthma', 'Child', 'Clinical Protocols', 'Combined Modality Therapy', 'Cross-Sectional Studies', 'Female', 'Follow-Up Studies', 'Hospitalization', 'Humans', 'Male', 'Patient Compliance', 'Severity of Illness Index', 'Treatment Outcome'] | 29,557,596 | [['M01.060.057'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['E02.183', 'N05.715.360.330.125'], ['E02.186'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effectiveness of critical incident stress debriefing with primary and secondary trauma victims. | Critical incident stress debriefing (CISD) (Mitchell, 1983) has been under intense scrutiny recently in the psychology literature. Several authors have concluded that CISD has no effect or even negative effects on victims of trauma (Bisson, McFarlane, & Rose, 2000; van Emmerik, Kamphuis, Hulsbosch, & Emmelkamp, 2002). ... | ['Crime Victims', 'Crisis Intervention', 'Emergency Medical Services', 'Emergency Medical Technicians', 'Humans', 'Primary Health Care', 'Stress Disorders, Post-Traumatic'] | 15,131,998 | [['M01.135'], ['F04.754.252'], ['N02.421.297'], ['M01.526.373.250', 'M01.526.485.067.150', 'N02.360.067.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.727'], ['F03.950.750.500']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
IgG responses to tissue-associated antigens as biomarkers of immunological treatment efficacy. | We previously demonstrated that IgG responses to a panel of 126 prostate tissue-associated antigens are common in patients with prostate cancer. In the current report we questioned whether changes in IgG responses to this panel might be used as a measure of immune response, and potentially antigen spread, following pro... | ['Algorithms', 'Antigens, Neoplasm', 'Artificial Intelligence', 'Bayes Theorem', 'Biomarkers, Tumor', 'Cancer Vaccines', 'Computational Biology', 'Humans', 'Immunoblotting', 'Immunoglobulin G', 'Male', 'Prostatic Neoplasms', 'Signal Transduction', 'Treatment Outcome', 'Vaccines, DNA'] | 21,197,272 | [['G17.035', 'L01.224.050'], ['D23.050.285'], ['G17.035.250', 'L01.224.050.375'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['D23.101.140'], ['D20.215.894.200'], ['H01.158.273.180', 'L01.313.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Interpretation and working through. | The function of insight is independent of content. Insight is the result of the assignment of meaning as distinct from finding meaning. Interpretation leads to insight which binds anxiety and lifts repression, thus providing relief of symptoms. Working is learning to apply the assigned meaning to new situations. | ['Anxiety', 'Attitude', 'Behavior Therapy', 'Cognition', 'Generalization, Psychological', 'Goals', 'Humans', 'Neurotic Disorders', 'Professional-Patient Relations', 'Psychoanalytic Interpretation', 'Psychoanalytic Therapy', 'Repression, Psychology', 'Self Concept'] | 1,163,696 | [['F01.470.132'], ['F01.100'], ['F04.754.137'], ['F02.463.188'], ['F02.463.425.357'], ['F01.658.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.550', 'F03.650'], ['F01.829.401.650', 'N05.300.660'], ['F04.628'], ['F04.754.709'], ['F01.393.821'], ['F01.752.747.792']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Corneal virulence of Staphylococcus aureus: roles of alpha-toxin and protein A in pathogenesis. | Staphylococcus aureus produces a variety of proteins, including alpha-toxin and protein A, that could contribute to corneal tissue damage during keratitis. We examined corneal infections produced by intrastromal injection of four S. aureus strains--three isogenic mutants, one lacking alpha-toxin (Hly- Spa+), one lackin... | ['Animals', 'Bacterial Toxins', 'Exotoxins', 'Hemolysin Proteins', 'Keratitis', 'Rabbits', 'Staphylococcal Protein A', 'Staphylococcus aureus', 'Virulence'] | 8,188,373 | [['B01.050'], ['D23.946.123'], ['D23.946.350'], ['D12.776.543.695.444'], ['C11.204.564'], ['B01.050.150.900.649.313.968.700'], ['D12.776.097.820', 'D23.050.161.821'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790.750.100'], ['G06.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results]. | Data obtained in this preliminary study show that in patients chronically treated either with Chlorimipramine (n = 6) or with Chlorpromazine (n = 2), significant amounts of the corresponding Nor1- and Nor2-metabolites were detected in plasma. The role of these metabolites in the overall therapeutic effect is under inve... | ['Chlorpromazine', 'Clomipramine', 'Depression', 'Dissociative Disorders', 'Humans', 'Imipramine'] | 6,525,292 | [['D02.886.369.198', 'D03.633.300.783.198'], ['D03.633.300.240.194'], ['F01.145.126.350'], ['F03.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.300.240.485']] | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A reverse genetics system for Borna disease virus. | Borna disease virus (BDV) is an enveloped virus. Its non-segmented, negative-stranded RNA genome has the coding capability for six main polypeptides and has an organization characteristic of members of the order Mononegavirales. However, based on its unique genetics and biological features, BDV is considered to be the ... | ['Animals', 'Borna disease virus', 'Cell Line', 'Cricetinae', 'Genome, Viral', 'RNA, Viral', 'Transcription, Genetic', 'Viral Proteins', 'Viral Structural Proteins', 'Virus Replication'] | 14,573,815 | [['B01.050'], ['B04.820.480.937.149.135'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['G05.360.340.358.840'], ['D13.444.735.828'], ['G02.111.873', 'G05.297.700'], ['D12.776.964'], ['D12.776.964.970'], ['G06.920.925']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Minimally invasive total hip arthroplasty--our clinical experience. | BACKGROUND: Minimally invasive prosthetic hip surgery (MIS) attempts to minimise the extent of the operation. The aim of the study was to describe minimally invasive hip surgery and to present early clinical experience of the authors.MATERIAL AND METHODS: 41 minimally invasive hip replacements through a posterior appro... | ['Adult', 'Arthroplasty, Replacement, Hip', 'Body Mass Index', 'Female', 'Follow-Up Studies', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Postoperative Complications', 'Radiography', 'Treatment Outcome'] | 17,514,172 | [['M01.060.116'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Skid resistance performance of asphalt wearing courses with electric arc furnace slag aggregates. | Metallurgical slags are by-products of the iron and steel industry and are subdivided into blast furnace slag and steel slag according to the different steel-producing processes. In Greece, slags are mostly produced from steelmaking using the electric arc furnace process, and subsequently are either disposed in a rando... | ['Conservation of Natural Resources', 'Construction Materials', 'Environmental Pollutants', 'Environmental Pollution', 'Hydrocarbons', 'Industrial Waste', 'Steel'] | 19,423,603 | [['J01.256', 'N06.230.080'], ['J01.637.241'], ['D27.888.284'], ['N06.850.460'], ['D02.455'], ['D20.944.420', 'N06.850.460.710.420'], ['D01.490.800', 'D01.552.033.847', 'D25.058.807', 'J01.637.051.058.807']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A contribution of image processing to the diagnosis of diabetic retinopathy--detection of exudates in color fundus images of the human retina. | In the framework of computer assisted diagnosis of diabetic retinopathy, a new algorithm for detection of exudates is presented and discussed. The presence of exudates within the macular region is a main hallmark of diabetic macular edema and allows its detection with a high sensitivity. Hence, detection of exudates is... | ['Algorithms', 'Color', 'Diabetic Retinopathy', 'Exudates and Transudates', 'Fluorescein Angiography', 'Fundus Oculi', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Observer Variation', 'Ophthalmoscopes', 'Ophthalmoscopy', 'Optic Disk', 'Pattern Recognition, Automated', 'Quality Control', '... | 12,585,705 | [['G17.035', 'L01.224.050'], ['G01.590.540.199'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['A12.383'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
[Changes in ageing pace and major immune parameters among individuals with long exposure to hydrogen sulfide]. | The authors revealed increase in ageing pace, higher level of pro-inflammatory cytokine Interleukin-8 and apoptosis marker (p53 protein) in individuals with chronic exposure to gas containing hydrogen sulfide. The immune parameters studied could serve as markers of premature ageing in individuals engaged into gas extra... | ['Adult', 'Aging, Premature', 'Air Pollutants, Occupational', 'Apoptosis', 'Case-Control Studies', 'Cytokines', 'Extraction and Processing Industry', 'Humans', 'Hydrogen Sulfide', 'Male', 'Middle Aged', 'Occupational Diseases', 'Occupational Exposure', 'Tumor Suppressor Protein p53'] | 21,938,919 | [['M01.060.116'], ['C23.888.069'], ['D27.888.284.101.268'], ['G04.146.954.035'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['J01.576.655.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.340', 'D01.362.350', ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Association of alkaline phosphatase with acute myocardial infarction in a population with high prevalence of hypovitaminosis D. | BACKGROUND: Since Pakistanis have high prevalence of hypovitaminosis-D as well as acute myocardial infarction (AMI), the objective of the study was to investigate the relationship between vitamin-D deficiency and risk of AMI in a hospital-based population and to identify major risk factors for this disease.METHODS: Fas... | ['25-Hydroxyvitamin D 2', 'Adult', 'Aged', 'Alanine Transaminase', 'Alkaline Phosphatase', 'Bone and Bones', 'Calcium', 'Case-Control Studies', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Humans', 'Isoenzymes', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Parathyroid Hormone', 'Risk Factors', 'Smoking', 'Tri... | 23,954,837 | [['D04.210.500.247.222.474.400', 'D04.210.500.247.808.412.400', 'D04.210.500.812.768.462.400', 'D10.570.938.439.500'], ['M01.060.116'], ['M01.060.116.100'], ['D08.811.913.477.700.100'], ['D08.811.277.352.650.035'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.318.372.500.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Angiostrongylus vasorum in Great Britain: a nationwide postal questionnaire survey of veterinary practices. | The lungworm, Angiostrongylus vasorum, was first reported in indigenous dogs in southwestern England in 1980 and has since been recorded in Wales, southeastern England and, more recently, in the West Midlands, northern England and Scotland. The nationwide distribution of the parasite was evaluated using a postal questi... | ['Angiostrongylus', 'Animals', 'Data Collection', 'Dog Diseases', 'Dogs', 'Hospitals, Animal', 'Postal Service', 'Strongylida Infections', 'Surveys and Questionnaires', 'United Kingdom'] | 24,852,845 | [['B01.050.500.500.294.400.968.588.080'], ['B01.050'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['N02.278.421.280', 'N06.230.150.360.250.200'], ['I01.451.617'], ['C01.610.335.508.700.775'], ['E05.318.308.980', 'N05.715.360.300.800', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly. | X-linked Dystonia-Parkinsonism (XDP) is a Mendelian neurodegenerative disease that is endemic to the Philippines and is associated with a founder haplotype. We integrated multiple genome and transcriptome assembly technologies to narrow the causal mutation to the TAF1 locus, which included a SINE-VNTR-Alu (SVA) retrotr... | ['Alternative Splicing', 'Alu Elements', 'Base Sequence', 'CRISPR-Cas Systems', 'Cohort Studies', 'Dystonic Disorders', 'Family', 'Female', 'Genetic Diseases, X-Linked', 'Genetic Loci', 'Genome, Human', 'Haplotypes', 'High-Throughput Nucleotide Sequencing', 'Histone Acetyltransferases', 'Humans', 'Induced Pluripotent S... | 29,474,918 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.080.708.330.800.800.050', 'G05.360.080.708.330.800.800.050', 'G05.360.340.024.425.800.800.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.203.374.394'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
A model of localised Rac1 activation in endothelial cells due to fluid flow. | Endothelial cells respond to fluid flow by elongating in the direction of flow. Cytoskeletal changes and activation of signalling molecules have been extensively studied in this response, including: activation of receptors by mechano-transduction, actin filament alignment in the direction of flow, changes to cell-subst... | ['Actin Cytoskeleton', 'Animals', 'Cell Polarity', 'Endothelial Cells', 'Enzyme Activation', 'Humans', 'Mechanotransduction, Cellular', 'Models, Biological', 'Pseudopodia', 'rac1 GTP-Binding Protein'] | 21,439,300 | [['A11.284.430.214.190.750.050'], ['B01.050'], ['G04.250'], ['A11.436.275'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.154.090.500', 'G02.111.820.580', 'G04.835.580'], ['E05.599.395'], ['A11.284.180.700'], ['D08.811.277.040.330.300.400.700.100.500', 'D12.644.360.525.700.100.100'... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Degradation of 2,4-dichlorophenol by using glow discharge electrolysis. | Degradation of 2,4-dichlorophenol (2,4-DCP) in aqueous by glow discharge electrolysis (GDE) has been investigated. Ultraviolet (UV) absorption spectra, atomic force microscopy (AFM), high performance liquid chromatography (HPLC) and gas chromatogram-mass spectrum (GC/MS) are used to monitor the degradation process and ... | ['Chlorophenols', 'Chromatography, High Pressure Liquid', 'Electrolysis', 'Gas Chromatography-Mass Spectrometry', 'Hydrogen-Ion Concentration', 'Kinetics', 'Microscopy, Atomic Force', 'Particle Size', 'Spectrophotometry, Ultraviolet', 'Ultraviolet Rays'] | 16,600,477 | [['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['E05.196.181.400.300'], ['E05.301.250'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['G02.712'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G01.358.500.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quality of Life after Radical Prostatectomy or Watchful Waiting With or Without Androgen Deprivation Therapy: The SPCG-4 Randomized Trial. | BACKGROUND: Men with prostate cancer experience adjuvant androgen deprivation therapy (ADT) differently.OBJECTIVE: To evaluate the effect of ADT on quality of life (QoL), patients' experience of clinical check-ups, and differences in cancer information as explanatory factors.DESIGN, SETTING, AND PARTICIPANTS: A study-s... | ['Aged', 'Androgen Antagonists', 'Finland', 'Humans', 'Male', 'Middle Aged', 'Models, Statistical', 'Prostatectomy', 'Prostatic Neoplasms', 'Quality of Life', 'Surveys and Questionnaires', 'Sweden', 'Treatment Outcome', 'Watchful Waiting'] | 31,100,237 | [['M01.060.116.100'], ['D06.347.065', 'D27.505.696.399.450.065'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E04.950.774.860.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Estrogen receptor status and adjuvant polychemotherapy or antiestrogen therapy in patients with high-risk breast cancer. | This pilot study includes 115 consecutive patients admitted in the period from 1978 to 1981. Patients eligible for this study were at high risk according to the TNM classification with stages pT1-pT3 and pN+, MO. Primary therapy included modified radical mastectomy and axillary-node clearance, one or more ipsilateral n... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Combined Modality Therapy', 'Estrogen Antagonists', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prognosis', 'Receptors, Estrogen', 'Tamoxifen'] | 6,736,112 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['E02.186'], ['D06.347.295', 'D27.505.696.399.450.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E01.789'], ['D12.776.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression of gyrB and 16S ribosomal RNA genes as indicators of growth and physiological activities of Legionella pneumophila. | To determine whether the DNA gyrase (gyrB) and 16S ribosomal RNA (16S rRNA) genes can be used as indicators of the biological activities of Legionella pneumophila, the expression levels were estimated. The ratio of mRNA/DNA in gyrB was 0.7 in mid log phase and decreased drastically after the log phase. For 16S rRNA, th... | ['Bacteriological Techniques', 'DNA Gyrase', 'Gene Expression', 'Legionella pneumophila', 'RNA, Messenger', 'RNA, Ribosomal, 16S'] | 25,817,815 | [['E01.370.225.875.150', 'E05.200.875.150'], ['D08.811.399.403.741.149', 'D12.776.097.237'], ['G05.297'], ['B03.440.400.425.450.450.500', 'B03.660.250.460.460.580'], ['D13.444.735.544'], ['D13.444.735.686.670']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Immunogenicity of a chimeric adenovirus type 5 vector with type 35 fiber containing HIV-1 gag in mice]. | OBJECTIVE: To study the immune effect of a chimeric adenovirus type 5 vector with type 35 fiber (rAd5/F35) vaccine in BALB/c mice.METHODS: The expression of HIV Gag protein was determined using indirect immunofluorescent staining. The rAd5/F35-mod.gag vector was injected intramuscularly to mice. The IgG antibody was de... | ['AIDS Vaccines', 'Adenoviridae', 'Animals', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Fluorescent Antibody Technique, Indirect', 'Gene Products, gag', 'Genetic Vectors', 'HIV Antibodies', 'HIV-1', 'Immunization', 'Immunoglobulin G', 'Mice', 'Mice, Inbred BALB C', 'Random Allocation', 'Recombinant Fusion Proteins... | 17,429,520 | [['D20.215.894.899.050'], ['B04.280.030'], ['B01.050'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparative Effect of <i>Acanthoscelides obtectus </i>(Say) Infestation on Nutrients of <i>Phaseolus vulgaris </i>(Linn.) and <i>Phaseolus acutifolius </i>(Gray). | BACKGROUND AND OBJECTIVE: Acanthoscelides obtectus is a destructive post-harvest pest of beans. The destructions caused by this beans weevil are of economic and nutritional importance. This study was carried out to compare the effect of A. obtectus infestation on the nutrients of Phaseolus vulgaris L. and Phaseolus acu... | ['Animals', 'Carbohydrates', 'Coleoptera', 'Dietary Fiber', 'Fatty Acids', 'Nigeria', 'Nutrients', 'Nutritive Value', 'Phaseolus', 'Phytochemicals', 'Seeds'] | 31,930,839 | [['B01.050'], ['D09'], ['B01.050.500.131.617.720.500.500.375'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['D10.251'], ['Z01.058.290.190.565'], ['G07.203.300.681', 'J02.500.681'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.850.601.750'], ['B01.650.940.800.575.912.250.401.649'], ['D23.704'], ['A18.024.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Correlation between virus genotype and chronicity rate in acute hepatitis C. | BACKGROUND/AIMS: Forty-two patients with the diagnosis of acute hepatitis C virus hepatitis were studied to investigate the relationship between hepatitis C virus genotype and progression to chronic infection.METHODS: The patients were followed for more than 1 year (mean age 29 years, male/female ratio 2.5). Intravenou... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Alanine Transaminase', 'Aspartate Aminotransferases', 'Bilirubin', 'Blood Transfusion', 'Case-Control Studies', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis C', 'Hepatitis C, Chronic', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Substance Abuse, Intravenous', '... | 9,672,167 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D08.811.913.477.700.100'], ['D08.811.913.477.700.225'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['E02.095.135'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.45... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Natural endocrine profiles of the group-living skunk anemonefish Amphiprion akallopisos in relation to their size-based dominance hierarchy. | Group-living animals commonly display differences in behaviour, physiology and endocrine profiles between conspecifics within the group, which are tightly linked to reproduction. Teleosts exhibit a variety of social systems, where social status, as well as sex, has been linked to different androgen and oestrogen profil... | ['Aggression', 'Androgens', 'Animals', 'Body Size', 'Breeding', 'Female', 'Fishes', 'Gonads', 'Male', 'Perciformes', 'Reproduction', 'Sex Characteristics', 'Social Dominance', 'Territoriality'] | 29,537,093 | [['F01.145.126.125', 'F01.145.813.045'], ['D27.505.696.399.472.161'], ['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.493'], ['A05.360.576', 'A06.300.312'], ['B01.050.150.900.493.602'], ['G08.686.784'], ['G08.686.815'], ['F... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Validity and reliability of the Turkish version of the Health Assessment Questionnaire for the Spondyloarthropathies. | The Health Assessment Questionnaire for Spondyloarthropathies (HAQ-S) was built by adding five new questions related with cervical and lumbar spine functions to HAQ by Daltroy et al. (in J Rheumatol 17(7):946-945, 1990). The aim of this study was to adapt the added five items into Turkish and then to test its reliabili... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Aged', 'Biomarkers', 'Blood Sedimentation', 'C-Reactive Protein', 'Cervical Vertebrae', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Observer Variation', 'Predictive Value of Tests', 'Quality of Life', 'Reproducibility of Results', 'Severity of I... | 21,327,435 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['E01.370.225.625.125', 'E05.200.625.125'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Humanities [K]', 'Diseases [C]', 'Information Science [L]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
An integrated calcium imaging processing toolbox for the analysis of neuronal population dynamics. | The development of new imaging and optogenetics techniques to study the dynamics of large neuronal circuits is generating datasets of unprecedented volume and complexity, demanding the development of appropriate analysis tools. We present a comprehensive computational workflow for the analysis of neuronal population ca... | ['Action Potentials', 'Calcium', 'Calcium Signaling', 'Cell Tracking', 'Connectome', 'Image Interpretation, Computer-Assisted', 'Molecular Imaging', 'Neurons', 'Programming Languages', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Software', 'Systems Integration', 'Voltage-Sensitive Dye Imaging'] | 28,591,182 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['E01.370.225.500.373', 'E01.370.350.557.500', 'E05.200.500.373', 'E05.242.373'], ['E01.370.350.578.875.500.249', 'E01.370.376.537.625.500.249', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Survey of medical attitudes towards a "case scenario" of encephalopathy after cardiac arrest]. | Recent studies have shown that the timing of death is often under the control of the physicians who treat the patient in intensive care unit (ICU), where death is commonly preceded by decisions either not to start an aggressive therapy or to discontinue life-sustaining therapy. The objective was to study end-of-life de... | ['Argentina', 'Attitude of Health Personnel', 'Attitude to Death', 'Cardiology', 'Critical Care', 'Decision Making', 'Female', 'Health Care Surveys', 'Heart Arrest', 'Humans', 'Male', 'Persistent Vegetative State', 'Resuscitation Orders', 'Terminal Care', 'Withholding Treatment'] | 19,414,298 | [['Z01.107.757.077'], ['F01.100.050', 'N05.300.100'], ['F01.100.125', 'N05.300.125'], ['H02.403.429.163'], ['E02.760.190', 'N02.421.585.190'], ['F02.463.785.373'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['C14.280.383'], ['B01.050.150.900.649.313.... | ['Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Non-use of Contraception by Canadian Youth Aged 15 to 24: Findings From the 2009-2010 Canadian Community Health Survey. | OBJECTIVES: Non-use of contraception is an important contributor to unintended pregnancy. This study assessed non-use of contraception and its determinants among Canadian youth aged 15 to 24.METHODS: Data from the 2009-2010 Canadian Community Health Survey respondents aged 15 to 24 were used to identify non-users of co... | ['Adolescent', 'Age Factors', 'Alcohol Drinking', 'Canada', 'Condoms', 'Contraception Behavior', 'Contraceptive Devices, Female', 'Contraceptives, Oral', 'Female', 'Health Surveys', 'Humans', 'Income', 'Indigenous Peoples', 'Logistic Models', 'Male', 'Odds Ratio', 'Pregnancy', 'Pregnancy, Unplanned', 'Risk Factors', 'S... | 30,316,712 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.145.317.269'], ['Z01.107.567.176'], ['E07.190.270.150'], ['F01.145.688.500', 'G08.686.784.891.500'], ['E07.190.250'], ['D27.505.696.875.360.276.210', 'D27.505.954.705.360.276.210'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.43... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
IgM and IgG responses to varicella-zoster virus p32/p36 complex after chickenpox and zoster, congenital and subclinical infections, and vaccination. | Varicella-zoster virus (VZV) directs the synthesis of a nonglycosylated polypeptide complex with two prominent species with relative molecular masses of 32,000 and 36,000; the p32/p36 complex is present in both the viral nucleocapsid and the nuclear matrix of the infected cell. We have now further characterized the hum... | ['Antibodies, Viral', 'Capsid', 'Chickenpox', 'Herpes Zoster', 'Herpesvirus 3, Human', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Macromolecular Substances', 'Molecular Weight', 'Precipitin Tests', 'Viral Core Proteins', 'Viral Vaccines'] | 2,536,788 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A21.249.500.250'], ['C01.925.256.466.930.250'], ['C01.925.256.466.930.750'], ['B04.280.382.100.900.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.39... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of degeneration of the intervertebral disk on the process of diffusion. | PURPOSE: To test the hypothesis that diffusion of contrast medium into the intervertebral disk is affected by the integrity of the nucleus pulposus and annulus fibrosus.METHODS: In canine intervertebral disks, defects were made in the annulus fibrosus and nuclear material was removed from the disk with a nucleotome. MR... | ['Animals', 'Contrast Media', 'Diffusion', 'Diskectomy', 'Dogs', 'Female', 'Gadolinium', 'Heterocyclic Compounds', 'Intervertebral Disc', 'Intervertebral Disc Displacement', 'Lumbar Vertebrae', 'Magnetic Resonance Imaging', 'Male', 'Organometallic Compounds', 'Postoperative Complications'] | 9,090,399 | [['B01.050'], ['D27.505.259.500', 'D27.720.259'], ['G01.202', 'G02.196'], ['E02.718.444', 'E04.188.350', 'E04.555.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['D03'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['C05.116.900.307', 'C23.300.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased hepatic glucose production and decreased hepatic glucose uptake at the prediabetic phase in the Otsuka Long-Evans Tokushima fatty rat model. | To investigate the time course of the hepatic glucose metabolism in non-insulin-dependent diabetes (NIDDM), we measured hepatic glucose production (HGP) and first-pass uptake of portal glucose infusion by the liver (HGU) using dual-tracer methods in a NIDDM model, Otsuka Long-Evans Tokushima Fatty (OLETF) rats, and in ... | ['Animals', 'Blood Glucose', 'Body Weight', 'Diabetes Mellitus, Type 2', 'Fasting', 'Glucose', 'Infusions, Intravenous', 'Liver', 'Male', 'Obesity', 'Portal Vein', 'Prediabetic State', 'Random Allocation', 'Rats', 'Rats, Inbred Strains'] | 9,711,984 | [['B01.050'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.452.394.750.149', 'C19.246.300'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D09.947.875.359.448'], ['E02.319.267.082.500', 'E02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Expression of CD44 isoforms and beta 1,6-branched oligosaccharides in human malignant melanoma is correlated with tumor progression but not with metastatic potential. | CD44, a family of closely related glycoproteins generated by alternative splicing, as well as the increased beta 1,6-branching of Asn-linked oligosaccharides (beta 1,6-branches), have been implicated in tumor progression and metastasis. We have investigated the expression of CD44 standard (CD44s), various CD44 splice v... | ['Disease Progression', 'Humans', 'Hyaluronan Receptors', 'Immunohistochemistry', 'Melanoma', 'Neoplasm Metastasis', 'Neoplasms, Second Primary', 'Oligosaccharides', 'Skin Neoplasms', 'Staining and Labeling'] | 9,138,110 | [['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.735.200.625', 'D12.776.395.550.200.625.144', 'D12.776.395.650.750.281', 'D12.776.543.550.200.625.144', 'D12.776.543.750.705.877.144', 'D23.050.301.350.625.144'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512',... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Japanese Alzheimer's Disease Neuroimaging Initiative: present status and future. | Japanese Alzheimer's Disease Neuroimaging Initiative (J-ADNI) was launched in 2008, aiming at conducting a longitudinal workup of a standardized neuroimaging, biomarker and clinico-psychological surveys. The research protocol was designed to maximize compatibility with that of US-ADNI, including structural magnetic res... | ['Aged', 'Alzheimer Disease', 'Apolipoprotein E4', 'Diagnostic Imaging', 'Disease Progression', 'Female', 'Health Planning Organizations', 'Humans', 'Japan', 'Male', 'Neuropsychological Tests', 'Psychometrics'] | 20,451,880 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D10.532.091.500.750', 'D12.776.070.400.500.750', 'D12.776.521.120.500.750'], ['E01.370.350'], ['C23.550.291.656'], ['N03.540.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['F04.711.513'],... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Trace elements in particulate matter from metropolitan regions of Northern China: Sources, concentrations and size distributions. | Public concerns over airborne trace elements (TEs) in metropolitan areas are increasing, but long-term and multi-site observations of size-resolved aerosol TEs in China are still lacking. Here, we identify highly elevated levels of atmospheric TEs in megacities and industrial sites in a Beijing-Tianjin-Hebei urban aggl... | ['Air Pollutants', 'Atmosphere', 'China', 'Environmental Monitoring', 'Particulate Matter', 'Trace Elements'] | 26,278,373 | [['D27.888.284.101'], ['G16.500.275.063', 'N06.230.300.100'], ['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D20.633'], ['D01.268.811', 'D27.505.696.494.555', 'G07.203.300.681.500.555', 'J02.500.681.500.555']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Ventricular tachyarrhythmias during cesarean section after ritodrine therapy: interaction with anesthetics. | This case illustrates that patients receiving ritodrine for preterm labor may risk interactions between the residual betamimetic effects of ritodrine and the effects of anesthetics during cesarean section. Such interactions may result in serious cardiovascular complications even after cessation of an infusion of ritodr... | ['Adult', 'Anesthesia, Epidural', 'Anesthesia, Obstetrical', 'Anesthetics', 'Cesarean Section', 'Drug Interactions', 'Female', 'Humans', 'Obstetric Labor, Premature', 'Pregnancy', 'Ritodrine', 'Tachycardia', 'Ventricular Fibrillation'] | 3,358,181 | [['M01.060.116'], ['E03.155.086.131'], ['E03.155.364'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['E04.520.252.500'], ['G07.690.773.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.420.491'], ['G08.686.784.769'], ['D02.033.100.624.870', 'D02.033.755.624.870', 'D02.092.063.624.870', 'D02.092.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The expression and regulation of adrenomedullin in the human endometrium: a candidate for endometrial repair. | After menstruation, the endometrium has a remarkable capacity for repair, but the factors involved remain undefined. We hypothesize adrenomedullin (AM) plays a role in this process. Premenstrually progesterone levels decline, stimulating prostaglandin (PG) synthesis, vasoconstriction, and hypoxia. This study aimed to d... | ['Adrenomedullin', 'Adult', 'Angiogenesis Inducing Agents', 'Cell Hypoxia', 'Cell Line', 'Cell Proliferation', 'Dinoprost', 'Endometrium', 'Endothelium, Vascular', 'Female', 'Gene Expression Regulation', 'Gene Silencing', 'Humans', 'Hypoxia-Inducible Factor 1', 'Lymphangiogenesis', 'Menstrual Cycle', 'Middle Aged', 'Or... | 21,558,311 | [['D06.472.699.077', 'D12.644.548.017'], ['M01.060.116'], ['D27.505.696.377.077.077'], ['G03.197.300', 'G04.270.300'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['A05.360.319.679.490'], ['A07.015.700.500', 'A10.272.491.355'], ['G05.308'], ['... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Exploratory factor analysis: health perceptions of Chinese early childhood educators in Hong Kong. | The aim of this study was to explore health perceptions of preschool teachers, with a view to inform early childhood practices and teacher education. Pre-service student-teachers and in-service teachers (n = 200) who were voluntarily recruited completed a 24-item health attitude questionnaire. Factor analysis identifie... | ['Adult', 'Attitude to Health', 'Child, Preschool', 'Factor Analysis, Statistical', 'Faculty', 'Female', 'Health Behavior', 'Health Education', 'Hong Kong', 'Humans', 'Male', 'Mental Health', 'Social Perception', 'Students', 'Surveys and Questionnaires', 'Universities', 'Young Adult'] | 20,435,652 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['M01.060.406.448'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['M01.526.702.250'], ['F01.145.488'], ['I02.233.332', 'N02.421.726.407'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['F02.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Isolation and characterization of the chick 14K beta-galactoside-binding lectin gene. | Vertebrate endogenous lectins have been implicated in cellular interactions that contribute to embryonic development. We have isolated a cloned segment of the gene for chick 14K type beta-galactoside-binding lectin from a genomic DNA library. Analysis of the structure of the cloned gene as well as the results of genomi... | ['Animals', 'Base Sequence', 'Blotting, Southern', 'Carrier Proteins', 'Chickens', 'Cloning, Molecular', 'Exons', 'Galactosides', 'Glycosides', 'Lectins', 'Molecular Sequence Data', 'Plasmids', 'Repetitive Sequences, Nucleic Acid', 'Restriction Mapping'] | 3,182,759 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['D12.776.157'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.393.220'], ['G05.360.340.024.340.137.232'], ['D09.408.320'], ['D09.408'], ['D12.776.503'], ['L01.453.245.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fasciola hepatica and Paramphistomum daubneyi: vertical distribution of metacercariae on plants under natural conditions. | Four experiments on the metacercariae of Fasciola hepatica and Paramphistomum daubneyi were carried out under natural conditions in order to study their vertical location on submerged plants and to determine whether simultaneous cercarial shedding of both digenea causes changes in the distributions of the metacercariae... | ['Animals', 'Fasciola hepatica', 'Paramphistomatidae', 'Poaceae', 'Snails'] | 15,338,293 | [['B01.050'], ['B01.050.500.500.736.715.408.380.420'], ['B01.050.500.500.736.715.600'], ['B01.650.940.800.575.912.250.822'], ['B01.050.500.644.400.750']] | ['Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and antimicrobial properties of substituted beta-aminoxypropionyl penicillins and cephalosporins. | Some beta-aminoxypropionyl penicillins (3) and cephalosporins (4 and 5), planned on the basis of the hypothesis that the (methyleneaminoxy)methyl group (greater than C = NOCH2) could be a "bioisoster" of either aryls or other aromatic groups, were synthesized and assayed for their antimicrobial properties. Compounds 3-... | ['Ampicillin', 'Cefotaxime', 'Cephalexin', 'Cephalosporins', 'Chemical Phenomena', 'Chemistry', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Microbial Sensitivity Tests', 'Molecular Structure', 'Penicillin G', 'Penicillins'] | 2,724,308 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['D02.065.589.099.249.200', 'D02.886.665.074.200', 'D03.633.100.300.249.200'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.30... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Release of iron from ferritin by 1,2,4-benzenetriol. | Release of iron from ferritin in the presence of polyhydroxy metabolites of benzene i.e., hydroquinone (HQ) or 1,2,4-benzenetriol (BT) was studied in acetate buffer, pH 5.6. The release of iron from ferritin was quantitated by monitoring the formation of iron-ferrozine complex. The presence of hydroquinone (330 microM)... | ['Acetates', 'Albumins', 'Aldehydes', 'Animals', 'Bleomycin', 'Bone Marrow', 'Bone Marrow Cells', 'Brain', 'Catalase', 'DNA', 'Dose-Response Relationship, Drug', 'Ferritins', 'Ferrozine', 'Homeostasis', 'Hydrogen-Ion Concentration', 'Hydroquinones', 'Iron', 'Lipid Peroxidation', 'Oxidation-Reduction', 'Rats', 'Superoxi... | 7,537,177 | [['D02.241.081.018', 'D10.251.400.045'], ['D12.776.034'], ['D02.047'], ['B01.050'], ['D09.400.420.110', 'D12.644.233.110'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['A08.186.211'], ['D08.811.682.732.332'], ['D13.444.308'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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