Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Functional complementation of a yeast knockout strain by Schistosoma mansoni Rho1 GTPase in the presence of caffeine, an agent that affects mutants defective in the protein kinase C signal transduction pathway. | In a previous study, the Schistosoma mansoni Rho1 protein was able to complement Rho1 null mutant Saccharomyces cerevisiae cells at restrictive temperatures and under osmotic stress (low calcium concentration) better than the human homologue (RhoA). It is known that under osmotic stress, the S. cerevisiae Rho1 triggers... | ['Animals', 'Caffeine', 'Genes, Helminth', 'Humans', 'Mutation', 'Protein Kinase C', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Schistosoma mansoni', 'Signal Transduction', 'rho GTP-Binding Proteins'] | 17,308,790 | [['B01.050'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['G05.360.340.024.340.310', 'G05.360.340.337.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['D08.811.913.696.620.682.700.725'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['B01.050.500.500.736.715.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of progesterone/estradiol ratio on pregnancy outcome of patients with high trigger-day progesterone levels undergoing gonadotropin-releasing hormone antagonist intracytoplasmic sperm injection cycles: a retrospective cohort study. | This study investigates the predictive power of serum progesterone/estradiol (P/E2) level for estimating the live birth rate in patients who had a serum progesterone (P) rate ? 1.5 ng/mL on the human chorionic gonadotropin (hCG) administration day and who received the gonadotropin-releasing hormone (GnRH) antagonist pr... | ['Adult', 'Birth Rate', 'Embryo Transfer', 'Estradiol', 'Female', 'Gonadotropin-Releasing Hormone', 'Humans', 'Pregnancy', 'Progesterone', 'Retrospective Studies', 'Sperm Injections, Intracytoplasmic'] | 30,280,612 | [['M01.060.116'], ['E05.318.308.985.775.500', 'N01.224.935.849.500', 'N06.850.505.400.975.775.500', 'N06.850.520.308.985.775.500'], ['E02.875.800.500', 'E05.820.800.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High dietary inorganic phosphate enhances cap-dependent protein translation, cell-cycle progression, and angiogenesis in the livers of young mice. | Inorganic phosphate (P(i)) plays a key role in diverse physiological functions. Recent studies have indicated that P(i) affects Akt signaling through the sodium-dependent phosphate cotransporter. Akt signaling, in turn, plays an important role in liver development; however, the effects of high dietary P(i) on the liver... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Carrier Proteins', 'Cell Cycle', 'Cell Cycle Proteins', 'Cell Proliferation', 'Cells, Cultured', 'Diet', 'Eukaryotic Initiation Factor-4E', 'Eukaryotic Initiation Factors', 'Fibroblast Growth Factor 2', 'Liver', 'Male', 'Matrix Metalloproteinase 2', 'Mice', 'Neovascu... | 18,703,640 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D12.776.157'], ['G04.144'], ['D12.776.167'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G07.203.650.240'], ['D12.776.157.725.750.374', 'D12.776.835.725.868.500.750'], ['D12.776.835.725.868'], ['D12.644.276.624.120', 'D12.776.467.624.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Silhouettea chaimi Goren, 1978, a junior synonym of Papillogobius melanobranchus (Fowler, 1934) (Teleostei: Gobiidae). | The high resemblance of Silhouettea chaimi Goren, 1978 to two Papillogobius species, P. melanobranchus and P. reichei was noticed from their published descriptions. The comparison of types of S. chaimi with comparative material of P. melanobranchus and P. reichei confirmed the lack of morphological differences between ... | ['Animals', 'Egypt', 'Female', 'Fishes', 'Male'] | 24,698,924 | [['B01.050'], ['Z01.058.266.317'], ['B01.050.150.900.493']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Long-term outcome of vaginal mesh or native tissue in recurrent prolapse: a randomized controlled trial. | INTRODUCTION AND HYPOTHESIS: Our aim was to evaluate clinically relevant long-term outcomes of transvaginal mesh or native tissue repair in women with recurrent pelvic organ prolapse (POP).METHODS: We performed a 7-year follow-up of a randomized controlled trial on trocar-guided mesh placement or native tissue repair i... | ['Adult', 'Female', 'Follow-Up Studies', 'Gynecologic Surgical Procedures', 'Humans', 'Middle Aged', 'Pelvic Organ Prolapse', 'Postoperative Complications', 'Reconstructive Surgical Procedures', 'Recurrence', 'Retrospective Studies', 'Surgical Mesh', 'Time Factors', 'Treatment Outcome', 'Uterine Prolapse', 'Vagina'] | 29,167,974 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.300.842.624'], ['C23.550.767'], ['E04.680'], ['C23.550.291.937'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association of cigarettes smoked daily with obesity in a general adult population. | OBJECTIVE: We analyzed the cross-sectional association between obesity and smoking habits, taking into account diet, physical activity, and educational level.RESEARCH METHODS AND PROCEDURES: We used data from the 2002 Swiss Health Survey, a population-based cross-sectional telephone survey assessing health and self-rep... | ['Adult', 'Aged', 'Body Mass Index', 'Child', 'Educational Status', 'Exercise', 'Female', 'Health Surveys', 'Humans', 'Middle Aged', 'Obesity', 'Odds Ratio', 'Prevalence', 'Smoking', 'Socioeconomic Factors', 'Switzerland'] | 17,495,208 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['N01.824.196'], ['G11.427.410.698.277', 'I03.350'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Successful cord blood transplantation in a patient with adult-onset common variable immunodeficiency]. | Common variable immunodeficiency (CVID) is the most frequently diagnosed congenital immunodeficiency and is characterized by dysfunctional antibody production. It often occurs at the age of ?10 years. Here we reported a case of a 46-year-old man confirmed with adult-onset CVID. He was effectively treated with cord bloo... | ['Agammaglobulinemia', 'B-Lymphocytes', 'Common Variable Immunodeficiency', 'Cord Blood Stem Cell Transplantation', 'Humans', 'Male', 'Middle Aged', 'T-Lymphocytes'] | 29,618,687 | [['C15.378.147.142', 'C15.604.515.032', 'C20.673.088'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C20.673.330'], ['E02.095.147.500.500.312', 'E04.936.225.687.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A1... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Macular degeneration and elevated serum ceruloplasmin. | Macular degeneration associated with age and drusen, an important cause of visual loss, is associated clinically with alterations in the retinal pigmented epithelium. Because the pigmented epithelium is a copper-rich tissue with antioxidant properties, the copper economy in patients and controls were studied by measuri... | ['Ceruloplasmin', 'Humans', 'Macular Degeneration', 'Osmolar Concentration', 'Reference Values', 'Transferrin'] | 3,793,397 | [['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12.776.157.160', 'D12.776.377.715.085.214', 'D12.776.556.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439'], ['G02.640'], ['E05.978.810'], ['D12.776.124.050.800', 'D12.776.124.790.223.839', 'D12.776.157.427.750.500', 'D12.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retamatrioside, a new flavonol triglycoside from Retama sphaerocarpa. | A new flavonol triglycoside, retamatrioside (1), has been isolated from the aerial parts of Retama sphaerocarpa. The structure of 1 has been determined as rhamnazin 3-O-beta-D-glucopyranosyl-(1-->5)-[beta-D-apiofuranosyl(1-->2)]-al pha -L-arabinofuranoside, using spectroscopic methods. | ['Carbohydrate Sequence', 'Fabaceae', 'Flavonoids', 'Glycosides', 'Hydrolysis', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'Plants, Medicinal', 'Spain', 'Spectrophotometry, Infrared', 'Spectrophotometry, Ultraviolet'] | 10,691,719 | [['G02.111.570.160', 'L01.453.245.667.160'], ['B01.650.940.800.575.912.250.401'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D09.408'], ['G02.380'], ['E05.196.867.519'], ['L01.453.245.667'], ['B01.650.560'], ['Z01.542.846'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.712.726.802', 'E05.196... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Transmitter release from presynaptic terminals of electric organ: inhibition by the calcium channel antagonist omega Conus toxin. | Cholinergic synaptosomes from electroplax of the ray Ommata discopyge release both ATP and ACh when depolarized with high K+ concentration in the presence of Ca2+. Others have shown that the ATP and ACh are released in the molar ratio found in isolated synaptic vesicles. Thus, it is assumed that the release of ATP refl... | ['Acetylcholine', 'Adenosine Triphosphate', 'Animals', 'Calcimycin', 'Calcium Channel Blockers', 'Electric Organ', 'Intermediate Filament Proteins', 'Membrane Potentials', 'Mollusk Venoms', 'Neuroeffector Junction', 'Neurofilament Proteins', 'Nitrendipine', 'Synaptosomes', 'Tetrodotoxin', 'Torpedo', 'omega-Conotoxin GV... | 3,112,325 | [['D02.092.211.111'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D03.633.100.221.173'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['A13.332'], ['D05.750.078.593', 'D12.776.220.475'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fetal echogenic cardiac foci: prospective postnatal electrocardiographic follow-up. | OBJECTIVE: To determine postnatal electrocardiographic abnormalities in fetuses with echogenic cardiac foci (ECF) and no congenital heart disease (CHD).STUDY DESIGN: A total of 41 fetuses with ECF and no CHD, were prospectively followed after birth with serial echocardiograms, electrocardiogram (ECG) and 24-h ECG (Holt... | ['Echocardiography', 'Electrocardiography, Ambulatory', 'Female', 'Fetal Heart', 'Follow-Up Studies', 'Gestational Age', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Male', 'Pregnancy', 'Prospective Studies', 'Ultrasonography, Prenatal'] | 21,836,548 | [['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['A07.541.278', 'A16.378.303'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G07.345.500.325.235.968', 'G08.686.320'], ['C14.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sociospatial distribution of access to facilities for moderate and vigorous intensity physical activity in Scotland by different modes of transport. | BACKGROUND: People living in neighbourhoods of lower socioeconomic status have been shown to have higher rates of obesity and a lower likelihood of meeting physical activity recommendations than their more affluent counterparts. This study examines the sociospatial distribution of access to facilities for moderate or v... | ['Automobiles', 'Bicycling', 'Exercise', 'Health Services Accessibility', 'Healthcare Disparities', 'Humans', 'Motor Vehicles', 'Multivariate Analysis', 'Obesity', 'Poverty', 'Public Facilities', 'Rural Population', 'Scotland', 'Social Class', 'Transportation', 'Urban Population', 'Walking'] | 22,568,969 | [['J01.937.500.100'], ['I03.450.642.845.140'], ['G11.427.410.698.277', 'I03.350'], ['N04.590.374.350', 'N05.300.430'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.937.500'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['C18.654.726.500', ... | ['Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Transient electroencephalographic suppression with initiation of cardiopulmonary bypass in pigs: blood versus nonblood priming. | Electroencephalographic (EEG) changes have been reported with cardiopulmonary bypass (CPB). We tested whether the type of priming solution (blood versus nonblood) affected the EEG. Twenty-six anesthetized pigs (29.5+/-1.6 kg) were cannulated for CPB primed with 1 liter plasmalyte and 500 ml 6% hetastarch (nonblood prim... | ['Animals', 'Cardiopulmonary Bypass', 'Electroencephalography', 'Electrolytes', 'Hydroxyethyl Starch Derivatives', 'Plasma Substitutes', 'Swine'] | 10,499,649 | [['B01.050'], ['E04.292.413'], ['E01.370.376.300', 'E01.370.405.245'], ['D01.248'], ['D09.301.915.500', 'D09.698.365.855.500'], ['D27.505.954.502.140.500'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of Toxocara and Toxascaris infection among human and animals in Iran with meta-analysis approach. | BACKGROUND: Toxocariasis is a worldwide zoonotic parasitic disease caused by species of Toxocara and Toxascaris, common in dogs and cats. Herein, a meta-analysis was contrived to assess the prevalence of Toxocara/Toxascaris in carnivore and human hosts in different regions of Iran from April 1969 to June 2019.METHODS: ... | ['Adolescent', 'Adult', 'Animals', 'Cats', 'Child', 'Child, Preschool', 'Dogs', 'Feces', 'Foxes', 'Host-Parasite Interactions', 'Humans', 'Infant', 'Iran', 'Jackals', 'Prevalence', 'Risk Factors', 'Seroepidemiologic Studies', 'Toxascaris', 'Toxocara canis', 'Toxocariasis', 'Young Adult'] | 31,910,815 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.750.250.216.200'], ['A12.459'], ['B01.050.150.900.649.313.750.250.216.250'], ['G16.527.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.70... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Urinary 11-dehydro-thromboxane B2: a quantitative index of platelet activation in cerebral infarction. | Thromboxane A2 (TXA2) biosynthesis was studied in healthy subjects, patients with chronic cerebral infarction, patients under chronic aspirin treatment and patients with atrial fibrillation. Urinary 11-dehydro-TXB2, as a major metabolite of TXA2, was measured by radioimmunoassay. The extent of carotid atherosclerosis w... | ['Adult', 'Aged', 'Arteriosclerosis', 'Aspirin', 'Atrial Fibrillation', 'Carotid Artery Diseases', 'Cerebral Infarction', 'Female', 'Humans', 'Male', 'Middle Aged', 'Platelet Activation', 'Thromboxane A2', 'Thromboxane B2'] | 1,392,173 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.137.126'], ['D02.455.426.559.389.657.410.595.176'], ['C14.280.067.198', 'C23.550.073.198'], ['C10.228.140.300.200', 'C14.907.253.123'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.2... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Moorean tree snail survival revisited: a multi-island genealogical perspective. | BACKGROUND: The mass extirpation of the island of Moorea's endemic partulid tree snail fauna, following the deliberate introduction of the alien predator Euglandina rosea, represents one of the highest profile conservation crises of the past thirty years. All of the island's partulids were thought to be extirpated by 1... | ['Animals', 'Conservation of Natural Resources', 'DNA, Mitochondrial', 'Extinction, Biological', 'Genetic Variation', 'Geography', 'Phylogeny', 'Polynesia', 'Sequence Analysis, DNA', 'Snails'] | 19,686,604 | [['B01.050'], ['J01.256', 'N06.230.080'], ['D13.444.308.283.225'], ['G16.510'], ['G05.365'], ['H01.277.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['Z01.639.760.815'], ['E05.393.760.700'], ['B01.050.500.644.400.750']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes. | The oncoprotein ErbB2 is endocytosis-deficient, probably due to its interaction with Heat shock protein 90. We previously demonstrated that clathrin-dependent endocytosis of ErbB2 is induced upon incubation of cells with Ansamycin derivatives, such as geldanamycin and its derivative 17-AAG. Furthermore, we have previou... | ['Animals', 'Benzoquinones', 'Cell Membrane', 'Cells, Cultured', 'Endocytosis', 'Lactams, Macrocyclic', 'Lysosomes', 'Models, Biological', 'Protein Kinase Inhibitors', 'Protein Multimerization', 'Proteolysis', 'Receptor, ErbB-2', 'Recombinant Fusion Proteins', 'Swine', 'Ubiquitin', 'Ubiquitination'] | 23,127,513 | [['B01.050'], ['D02.806.250'], ['A11.284.149'], ['A11.251'], ['G04.417'], ['D02.065.589.327', 'D04.345.295'], ['A11.284.430.214.190.875.190.550'], ['E05.599.395'], ['D27.505.519.389.755'], ['G02.111.694'], ['G02.111.720', 'G03.812'], ['D08.811.913.696.620.682.725.400.009.400', 'D12.776.543.750.630.009.400', 'D12.776.54... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neighborhood physical food environment and cardiovascular risk factors in India: Cross-sectional evidence from APCAPS. | There has been increasing interest in associations between neighborhood food environments and cardiovascular risk factors. However, results from high-income countries remain inconsistent, and there has been limited research from low- and middle-income countries. We conducted a cross-sectional analysis of the third wave... | ['Adolescent', 'Adult', 'Blood Pressure', 'Cardiovascular Diseases', 'Cross-Sectional Studies', 'Female', 'Food', 'Humans', 'India', 'Male', 'Middle Aged', 'Residence Characteristics', 'Risk Factors', 'Young Adult'] | 31,473,412 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['N01.224.791', 'N06.850.505.400.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Association of plasma vitamin C concentration to total and cause-specific mortality: a 16-year prospective study in China. | BACKGROUND: Vitamin C insufficiency occurs across many countries and has been hypothesised to increase risk of various diseases. Few prospective studies with measured circulating vitamin C have related deficiency to disease mortality, particularly in low-income and middle-income countries.METHODS: We randomly selected ... | ['Aged', 'Aged, 80 and over', 'Ascorbic Acid', 'Biomarkers', 'Cardiovascular Diseases', 'Cause of Death', 'China', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Neoplasms', 'Prospective Studies', 'Seasons'] | 30,100,578 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D23.101'], ['C14'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Divergent function in the crotonase superfamily: an anhydride intermediate in the reaction catalyzed by 3-hydroxyisobutyryl-CoA hydrolase. | 3-Hydroxyisobutyryl-CoA hydrolase (HICH), a member of the enoyl-CoA (crotonase) superfamily, catalyzes the hydrolysis of 3-hydroxyisobutyryl-CoA to 3-hydroxyisobutyrate. Like other members of the superfamily, the sequence of HICH contains conserved sequences for an oxyanion hole that stabilizes anionic intermediates. I... | ['Anhydrides', 'Binding Sites', 'Catalysis', 'Enoyl-CoA Hydratase', 'Hydrolysis', 'Oxygen', 'Pseudomonas aeruginosa', 'Thiolester Hydrolases'] | 14,518,977 | [['D02.113'], ['G02.111.570.120'], ['G02.130'], ['D08.811.520.241.300.250'], ['G02.380'], ['D01.268.185.550', 'D01.362.670'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['D08.811.277.352.897']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Posterior lamellar disc dislocation into the vitreous cavity during descemet stripping automated endothelial keratoplasty. | We present a case of a dislocated posterior lamellar lenticule into the vitreous cavity during Descemet stripping automated endothelial keratoplasty. After insertion of the donor disc in a partially vitrectomized eye with partial iris loss, the graft dislocated into the vitreous cavity. With a standard 3-port vitrectom... | ['Automation', 'Corneal Diseases', 'Corneal Transplantation', 'Descemet Membrane', 'Endothelium, Corneal', 'Humans', 'Intraoperative Complications', 'Lens Subluxation', 'Male', 'Middle Aged', 'Ultrasonography', 'Vitreous Body'] | 19,092,415 | [['J01.897.104'], ['C11.204'], ['E02.095.147.725.225', 'E04.540.825.374', 'E04.936.580.225'], ['A09.371.060.217.271', 'A10.615.179.437'], ['A09.371.060.067.318', 'A09.371.060.217.318', 'A10.272.491.318'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505'], ['C11.510.598'], ['M01.060.116.630'], ['E01.370.3... | ['Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Nanoencapsulation of psoralidin via chitosan and Eudragit S100 for enhancement of oral bioavailability. | Psoralidin (PL) has recently been attracting more attention as a new anticancer agent candidate. Nevertheless, peroral administration of PL is largely challenged by its insoluble nature and intestinal efflux. This article aimed to develop a nanoencapsulation formulation of PL using water-soluble chitosan and Eudragit S... | ['Administration, Oral', 'Animals', 'Benzofurans', 'Biological Availability', 'Chemistry, Pharmaceutical', 'Chitosan', 'Coumarins', 'Nanocapsules', 'Polymethacrylic Acids', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley'] | 27,154,253 | [['E02.319.267.100'], ['B01.050'], ['D03.633.100.127'], ['G03.787.151', 'G07.690.725.129'], ['H01.158.703.007', 'H01.181.466'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D26.255.260.575', 'E02.319.300.380.575', 'J01.637.512.600.575'], ['D02.241.081.069.800', 'D05.750.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Effect of anthracycline analogs on photolabelling of p-glycoprotein by [125I]iodomycin and [3H]azidopine: relation to lipophilicity and inhibition of daunorubicin transport in multidrug resistant cells. | Eight anthracycline analogs that have been shown to modulate multidrug resistance (Friche et al., Biochem. Pharmacol., 39, 1721-1726; 1990) were tested for their inhibitory effect on the photolabelling of P-glycoprotein. We photoaffinity labelled P-glycoprotein in daunorubicin (DNR) resistant Ehrlich ascites tumour cel... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Affinity Labels', 'Animals', 'Antibiotics, Antineoplastic', 'Azides', 'Binding, Competitive', 'Biological Transport', 'Carcinoma, Ehrlich Tumor', 'Daunorubicin', 'Detergents', 'Dihydropyridines', 'Doxorubicin', 'Drug Resistance', 'Iodine Radioisotopes', 'Memb... | 8,094,288 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D27.720.470.410.080'], ['B01.050'], ['D27.505.954.248.106'], ['D01.625.100', 'D02.159'], ['E05.196.080', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Modeling the effects of biomass accumulation on the performance of a biotrickling filter packed with PUF support for the alkaline biotreatment of dimethyl disulfide vapors in air. | Excess biomass buildup in biotrickling filters leads to low performance. The effect of biomass accumulation in a biotrickling filter (BTF) packed with polyurethane foam (PUF) was assessed in terms of hydrodynamics and void space availability in a system treating dimethyl disulfide (DMDS) vapors with an alkaliphilic con... | ['Air Filters', 'Bacteria', 'Biomass', 'Bioreactors', 'Disulfides', 'Filtration', 'Magnetic Resonance Imaging', 'Microbial Consortia', 'Models, Theoretical'] | 25,056,290 | [['E05.196.454.201', 'E07.039'], ['B03'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E07.115', 'J01.897.120.115'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['E05.196.454', 'G01.280', 'G02.263'], ['E01.370.350.825.500'], ['G06.591.750', 'G16.500.275.157.049.100.500.750', 'N06.230.124.049... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Lichen communities along a pollution gradient 40 years after decommissioning of a Cu-Ni smelter. | Pollution control initiatives in Greater Sudbury, Ontario, Canada, resulted in the decommissioning of the Coniston Smelter in 1972. The last assessment of the effects from the smelter on the surrounding lichen biota was in 1990, which showed an overall improvement in richness following these initiatives, but still few ... | ['Canada', 'Copper', 'Environmental Monitoring', 'Environmental Pollutants', 'Lichens', 'Metallurgy', 'Nickel', 'Time Factors'] | 25,598,157 | [['Z01.107.567.176'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['B01.300.340', 'B05.350'], ['J01.576.655.875.400'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['G01.910.857']] | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Active sensitization and occupational allergic contact dermatitis caused by para-tertiary-butylcatechol. | Para-tertiary-butylcatechol (PTBC) is a rare allergen which is used in the rubber, paint and petroleum industries. We present 9 patients who were sensitized to PTBC and examined at the Finnish Institute of Occupational Health (FIOH) between 1974 and 1995. 3 of the patients had been exposed to PTBC in their work. 2 of t... | ['Adhesives', 'Adult', 'Antioxidants', 'Catechols', 'Dermatitis, Allergic Contact', 'Dermatitis, Occupational', 'Dose-Response Relationship, Drug', 'Ethylenediamines', 'Female', 'Finland', 'Formaldehyde', 'Humans', 'Immunization', 'Male', 'Middle Aged', 'Occupational Exposure', 'Patch Tests', 'Phenols', 'Phenylenediami... | 9,506,222 | [['D27.720.013', 'J01.637.016'], ['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.657.166'], ['C17.800.174.255.100', 'C17.800.815.255.100', 'C20.543.418.150'], ['C17.800.174.255.700', 'C17.800.815.255.700', 'C24.270'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.09... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Success with coronary angioplasty as seen at demonstrations of procedure. | To assess the real-life results of coronary angioplasty, unidentified participants made notes on 104 cases demonstrated live at twelve international angioplasty courses in 1991. The initially planned procedure was successful in 73% with crossover to another device in 20% for an ultimate success rate of 93%. Interventio... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angioplasty, Balloon, Coronary', 'Cardiac Surgical Procedures', 'Coronary Disease', 'Coronary Vessels', 'Female', 'Humans', 'Intraoperative Complications', 'Male', 'Middle Aged', 'Treatment Failure', 'Treatment Outcome'] | 1,359,269 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E04.100.376', 'E04.928.220'], ['C14.280.647.250', 'C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Radiation-induced performance decrement. | This article is a brief review of performance decrement expected after low-level radiation doses (0.70 Gy or less) and after higher radiation doses. Examples are presented from both animal and human data. The data indicate that low-level radiation doses in humans are not expected to degrade performance on the battlefie... | ['Animals', 'Humans', 'Military Personnel', 'Radiation Dosage', 'Radiation Injuries'] | 11,873,495 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360']] | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nosocomial Acinetobacter pneumonia: Treatment and prognostic factors in 356 cases. | BACKGROUND AND OBJECTIVE: Acinetobacter baumannii and A. baumannii/calcoaceticus complex are commonly encountered pathogens in nosocomial infections. This study aimed to evaluate the treatment and prognostic risk factors in nosocomial pneumonia caused by these microorganisms.METHODS: The study was conducted retrospecti... | ['Acinetobacter Infections', 'Acinetobacter baumannii', 'Acinetobacter calcoaceticus', 'Adult', 'Aged', 'Anti-Bacterial Agents', 'Cross Infection', 'Drug Resistance, Bacterial', 'Female', 'Humans', 'Imipenem', 'Male', 'Middle Aged', 'Pneumonia, Bacterial', 'Pneumonia, Ventilator-Associated', 'Prognosis', 'Retrospective... | 26,635,315 | [['C01.150.252.400.560.022'], ['B03.440.400.425.537.050.099', 'B03.660.250.530.050.099'], ['B03.440.400.425.537.050.200', 'B03.660.250.530.050.200'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['C01.248', 'C23.550.291.875.500'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.15... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Do prominent quality measurement surveys capture the concerns of persons with disability? | BACKGROUND: Demonstration programs nationwide aim to control costs and improve care for people dually-eligible for Medicare and Medicaid, including many persons with disability. Ensuring these initiatives maintain or improve care quality requires comprehensive evaluation of quality of care.OBJECTIVES: To examine whethe... | ['Adult', 'Disabled Persons', 'Government Programs', 'Health', 'Health Care Surveys', 'Health Services for Persons with Disabilities', 'Humans', 'Massachusetts', 'Medicaid', 'Medicare', 'Models, Theoretical', 'Program Evaluation', 'Quality Improvement', 'Quality Indicators, Health Care', 'Quality of Health Care', 'Qual... | 28,185,857 | [['M01.060.116'], ['M01.150'], ['I01.451'], ['N01.400'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N02.421.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.550.510'], ['N03.219.521.346.506.564.655', 'N03.706.615.693'], ['N... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Parent ion scans of unseparated peptide mixtures. | The nanoelectrospray ion source (NanoES) developed recently has proven to be an excellent tool for the sequencing of peptides out of unseparated mixtures. At lower levels of analyte, however, it is increasingly difficult to distinguish the peptide ions in the spectrum, limiting the overall sensitivity of the procedure.... | ['Amino Acid Sequence', 'Mass Spectrometry', 'Molecular Sequence Data', 'Peptides', 'Sequence Analysis'] | 8,712,361 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.566'], ['L01.453.245.667'], ['D12.644'], ['E05.393.760']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Multiple enamel pearls in two siblings detected by volumetric computed tomography. | A rare case of multiple enamel pearl formation is presented involving the maxillary molars in two siblings incidentally recognized during volumetric CT examination. Although the pathogenesis of ectopic enamel formation is not known, possible mechanisms to account for this phenomenon are discussed in the context of curr... | ['Adolescent', 'Adult', 'Dental Enamel', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Molar', 'Tomography, X-Ray Computed', 'Tooth Abnormalities', 'Tooth Cervix', 'Tooth Root'] | 18,460,580 | [['M01.060.057'], ['M01.060.116'], ['A14.549.167.900.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['A14.549.167.860.525'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Value of Multiparametric US in the Assessment of Intratesticular Lesions. | Purpose To evaluate the diagnostic accuracy of multiparametric ultrasonography (US) consisting of gray-scale US, color Doppler US, strain elastography, and contrast agent-enhanced US in the assessment of intratesticular lesions. Materials and Methods Institutional review board approval was obtained for this retrospecti... | ['Adult', 'Contrast Media', 'Elasticity Imaging Techniques', 'Humans', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Retrospective Studies', 'Testicular Neoplasms', 'Ultrasonography', 'Young Adult'] | 28,628,420 | [['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.850.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.567'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Life-threatening asthma: pathophysiology and management. | Asthma prevalence and mortality have been increasing over the past 2 decades, despite advances in medical therapy. In 2003 the National Health Interview Survey reported over 4,000 asthma-related deaths. A small proportion of people with severe asthma use a large proportion of health-care resources and bear the burden o... | ['Adolescent', 'Adult', 'Asthma', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Respiration, Artificial', 'Severity of Illness Index', 'United States'] | 18,501,027 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Indole-based analogs of melatonin: in vitro antioxidant and cytoprotective activities. | The known neuroprotective actions of melatonin could be due to its antioxidant or radical scavenging activity, or they could be due to specific interactions of the indole with its receptors. A study of structure-activity relationships may provide useful information when a validated macromolecular target has not been (o... | ['Animals', 'Antioxidants', 'Cell Survival', 'Female', 'Indoles', 'Melatonin', 'Neurons', 'Rats'] | 14,962,060 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.346'], ['D03.633.100.473'], ['D03.633.100.473.914.481', 'D06.472.506'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Re-exposure to recombinant (r)-hirudin in antihirudin antibody-positive patients with a history of heparin-induced thrombocytopenia. | Patients with a history of heparin-induced thrombocytopenia (HIT) and antibodies to hirudin were re-exposed to recombinant (r)-hirudin for prophylaxis of thromboembolism. Four patients were re-exposed to 2 x 25 mg of subcutaneous r-hirudin for 8-27 d. Two patients were re-exposed once, one patient twice and one four ti... | ['Adult', 'Aged', 'Antibodies', 'Anticoagulants', 'Female', 'Heparin', 'Hirudin Therapy', 'Hirudins', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Male', 'Middle Aged', 'Recombinant Proteins', 'Thrombocytopenia', 'Thromboembolism', 'Whole Blood Coagulation Time'] | 10,848,825 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D27.505.954.502.119'], ['D09.698.373.400'], ['E02.319.913.500'], ['D12.644.861.060.875', 'D12.776.872.060.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
High prevalence of IgG4-related lymphoplasmacytic infiltrative disorder in 25 patients with orbital inflammation: a retrospective case series. | AIMS: To evaluate retrospectively the prevalence of positive IgG4-immunostaining in orbital tissue of patients with idiopathic orbital inflammation and to compare the clinical, radiographic and pathologic features among patients with and without IgG4-positive cells.PATIENTS AND METHODS: 25 patients with biopsy-proven i... | ['Adult', 'Aged', 'Aged, 80 and over', 'Exophthalmos', 'Eye Pain', 'Female', 'Humans', 'Immunoglobulin G', 'Immunohistochemistry', 'Lymphatic Diseases', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Ocular Motility Disorders', 'Orbital Pseudotumor', 'Plasma Cells', 'Prevalence', 'Retrospective Studies', 'Tomogr... | 23,759,440 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.675.349'], ['C11.300.500', 'C23.888.307.625', 'C23.888.592.612.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E01.370.225.500.607.51... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Strategies to foster an adequate compromise of the pharmacist with respect to over the counter medicines’ advertisement.] | The advertisement has a great influence on the public and, in over the counter medicines (OTC), it can generate health risks on the population if it is misregulated. The aim of this work is to analyze and disclose strategic viable actions emerged from a forum debate during an online course for fostering the pharmacist’... | ['Advertising', 'Argentina', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Legislation, Drug', 'Nonprescription Drugs', 'Pharmacists', 'Professional Role'] | 30,734,701 | [['J01.219.687.274', 'L01.143.050'], ['Z01.107.757.077'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.605', 'N03.706.615.402'], ['D26.530'], ['M01.526.485.780', 'N02.360.780'], ['F01.829.316.616.625']] | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Depressive symptoms and cigarette smoking in American workers. | PURPOSE: This study examined the relationship between depressive symptoms and cigarette smoking in a large sample of American workers.METHODS: We used data from the National Survey of Midlife Development in the United States. Seventy percent of individuals completed a telephone survey. The present study focused on 2593... | ['Adult', 'Aged', 'Depression', 'Employment', 'Female', 'Humans', 'Male', 'Middle Aged', 'Salaries and Fringe Benefits', 'Smoking', 'United States'] | 16,422,136 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.126.350'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N01.824.417.700', 'N04.452.677.800'], ['F01.145.805'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical. | It has been shown that BH(4) ameliorates endothelial dysfunction associated with conditions such as hypertension, cigarette smoking, and diabetes. This effect has been proposed to be due to a superoxide scavenging activity of BH(4). To examine this possibility we determined the rate constant for the reaction between BH... | ['Ascorbic Acid', 'Biopterin', 'Electron Spin Resonance Spectroscopy', 'Free Radical Scavengers', 'Free Radicals', 'Kinetics', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type III', 'Oxidation-Reduction', 'Pterins', 'Superoxides'] | 11,595,382 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D03.633.100.733.631.202', 'D08.211.090'], ['E05.196.867.519.274'], ['D27.505.519.217.500'], ['D01.339', 'D02.389'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.664.500.772'], ['D08.811.682.664.500.772.750'], ['G02.700', 'G03.295.531'], ['D03.633.100.73... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of maturation on muscle quality of the lower limb muscles in adolescent boys. | BACKGROUND: The purpose of this study was to clarify the effect of maturation on the muscle quality of the lower limb muscles around puberty.METHODS: Subjects were 117 Japanese boys age 12 to 15 years. The maturity status was assessed by using a self-assessment of stage of pubic hair development based on the criteria o... | ['Adolescent', 'Child', 'Humans', 'Japan', 'Linear Models', 'Lower Extremity', 'Male', 'Muscle Strength', 'Sexual Maturation'] | 25,239,758 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['A01.378.610'], ['E01.37... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reduction of oral flora with ciprofloxacin in healthy volunteers. | The effect of a short course of ciprofloxacin on the oral microflora was examined in 16 healthy volunteers. Salivary specimens were collected before and after two 750 mg doses of ciprofloxacin administered 12 h apart. Salivary bacteria were identified to species level, and total quantitative colony counts were determin... | ['Adolescent', 'Adult', 'Aged', 'Bacteria', 'Bacterial Infections', 'Ciprofloxacin', 'Head and Neck Neoplasms', 'Humans', 'Middle Aged', 'Mouth', 'Saliva', 'Surgical Wound Infection'] | 3,360,683 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B03'], ['C01.150.252'], ['D03.633.100.810.835.322.186'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['A12.200.666'], ['C01.947.692', 'C23.550.767.925']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Analysis strategy of protein-protein interaction networks. | Protein interactions, as well as the networks they formed, play a key role in many cellular processes and the distortion of the protein interacting interfaces may lead to the development of many diseases. In this chapter, we will briefly introduce the background knowledge of the protein-protein interaction, followed by... | ['Cluster Analysis', 'Computational Biology', 'Computer Simulation', 'DNA-Binding Proteins', 'Databases, Protein', 'Gene Expression', 'Humans', 'Internet', 'Microarray Analysis', 'Protein Interaction Maps', 'Saccharomyces', 'Software', 'Systems Biology'] | 23,192,546 | [['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['D12.776.260'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['G05.297'], ['B01.050.150.900.649.313.988.400.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[A comparison between chromic catgut and polyglycolic acid sutures in episiotomy repair (author's transl)]. | Polyglycolic acid sutures (Dexon) were compared to chromic catgut sutures in episiotomy repair. When polyglycolic acid sutures were used, the degree of postpartum perineal pain was approximately half as great, and the incidence of dehiscence of episiotomy was 3--5 times greater in the chromic catgut group. The cosmetic... | ['Adult', 'Chromium', 'Episiotomy', 'Female', 'Humans', 'Pain', 'Polyglycolic Acid', 'Pregnancy', 'Prospective Studies', 'Surgical Wound Dehiscence', 'Suture Techniques', 'Sutures'] | 342,330 | [['M01.060.116'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['E04.520.252.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['D05.750.728.780', 'D25.720.728.780', 'J01.637.051.720.728.780'], ['G08.686.784.769'], ['E05.318.372.500.750.625'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
A class of chaotic bird calls? | Evidence is presented that the basic vocalized sound produced by some cockatoos, specifically the Australian sulfur-crested cockatoo (Cacatua galerita) and the gang-gang cockatoo (Callocephalon fimbriatum), has a chaotic acoustic structure rather than the harmonic structure characteristic of most birdsongs. These findi... | ['Animals', 'Birds', 'Sound Spectrography', 'Vocalization, Animal'] | 10,955,649 | [['B01.050'], ['B01.050.150.900.248'], ['E05.855'], ['F01.145.113.055.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuropsychological performance in posttraumatic epilepsy. | Performances on the Wechsler-Bellevue Intelligence Scale and on Halstead's neuropsychological measures were investigated in two groups of adult subjects with posttraumatic seizures. One of the groups, in addition to seizures, had abnormal and persistent focal cortical signs. The other group had seizures only and no oth... | ['Adult', 'Epilepsy, Post-Traumatic', 'Humans', 'Intelligence Tests'] | 416,953 | [['M01.060.116'], ['C10.228.140.199.650', 'C10.228.140.490.380', 'C10.900.300.087.600', 'C26.915.300.200.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.141.493']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Design, Optimization, and Evaluation of Lurasidone Hydrochloride Nanocrystals. | The present investigation was carried out to design, optimize, and evaluate lurasidone hydrochloride nanocrystals for improving its solubility and dissolution characteristics. Nanocrystals were prepared by media milling technique using zirconium oxide beads with 0.1 mm diameter. Various stabilizers, viz. poloxamer 188,... | ['Calorimetry, Differential Scanning', 'Chemistry, Pharmaceutical', 'Freeze Drying', 'Lurasidone Hydrochloride', 'Nanoparticles', 'Particle Size', 'Powders', 'Solubility', 'X-Ray Diffraction'] | 26,586,537 | [['E05.196.131.310', 'E05.196.370.310'], ['H01.158.703.007', 'H01.181.466'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', 'E05.200.500.620.760.160.260', 'E05.200.750.600.760.160.260', 'E05.760.156.260'], ['D02.886.675.414', 'D03.383.129.708.414', 'D03.633.100.513.437'], ['J0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Muc5ac mucin expression during rat skin development. | UNLABELLED: Some mucin genes have been detected during human embryonic and fetal organ development; however, little is known about mucin expression in epidermal development, neither in humans nor in other species. The present research was developed to explore Muc5ac skin expression during prenatal and postnatal rat dev... | ['Animals', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Gene Expression Regulation, Developmental', 'Immunohistochemistry', 'Mucin 5AC', 'Rats', 'Skin'] | 25,820,562 | [['B01.050'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.308.310'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['D12.776.395... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Predation as a cause of neurologic signs and acute mortality in a pheasant flock. | A flock of approximately 15,000 ring-necked pheasants (Phasianus colchicus) was evaluated for a sudden increase in mortality and acute neurological signs after having been previously diagnosed 3 wk earlier with a chronic respiratory disease of undetermined etiology. Approximately 25 live birds were displaying neurologi... | ['Animals', 'Bird Diseases', 'Female', 'Galliformes', 'Male', 'Mustelidae', 'Nervous System Diseases', 'Predatory Behavior', 'Skin', 'Skull'] | 17,039,853 | [['B01.050'], ['C22.131'], ['B01.050.150.900.248.350'], ['B01.050.150.900.649.313.750.250.575'], ['C10'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['A17.815'], ['A02.835.232.781']] | ['Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heart rate variability and the risk of Parkinson disease: The Atherosclerosis Risk in Communities study. | OBJECTIVE: Autonomic dysfunction frequently occurs in the context of Parkinson disease (PD) and may precede onset of motor symptoms. Limited data exist on the prospective association of heart rate variability (HRV), a marker of autonomic function, with PD risk.METHODS: We included 12,162 participants of the Atheroscler... | ['Atherosclerosis', 'Bradycardia', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Parkinson Disease', 'Prospective Studies', 'Residence Characteristics', 'Risk Factors'] | 25,707,861 | [['C14.907.137.126.307'], ['C14.280.067.319', 'C23.550.073.300'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.40... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changes in glucosinolate concentrations, myrosinase activity, and production of metabolites of glucosinolates in cabbage (Brassica oleracea Var. capitata) cooked for different durations. | In cabbage, glucosinolates such as sinigrin are hydrolyzed by plant myrosinase to allyl isothiocyanate (AITC), allyl cyanide, and, in the presence of an epithiospecifier protein, 1-cyano-2,3-epithiopropane (CEP). Isothiocyanates have been implicated in the cancer-protective effects of Brassica vegetables. The effect of... | ['Brassica', 'Glucosinolates', 'Glycoside Hydrolases', 'Hot Temperature', 'Hydrolysis', 'Time Factors'] | 17,002,432 | [['B01.650.940.800.575.912.250.157.200'], ['D02.886.740.703.350', 'D09.408.348.820.350', 'D09.408.903.703.350'], ['D08.811.277.450'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.380'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Crystal structure of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011 complexed with 1-deoxynojirimycin at 2.0 A resolution. | 1-Deoxynojirimycin, a pseudo-monosaccharide, is a strong inhibitor of glucoamylase but a relatively weak inhibitor of cyclodextrin glucanotransferase (CGTase). To elucidate this difference, the crystal structure of the CGTase from alkalophilic Bacillus sp. 1011 complexed with 1-deoxynojirimycin was determined at 2.0 A ... | ['1-Deoxynojirimycin', 'Acarbose', 'Bacillus', 'Binding Sites', 'Crystallography, X-Ray', 'Enzyme Inhibitors', 'Glucan 1,4-alpha-Glucosidase', 'Glucosyltransferases', 'Hydrogen Bonding', 'Maltose', 'Models, Molecular', 'Protein Conformation', 'Water'] | 11,275,559 | [['D02.491.567.500.033', 'D03.132.014', 'D03.383.621.300.033', 'D09.553.500.033'], ['D09.698.629.802.100'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['D27.505.519.389'], ['D08.811.277.45... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Summertime ambient formaldehyde in five U.S. metropolitan areas: Nashville, Atlanta, Houston, Philadelphia, and Tampa. | First, we briefly review the atmospheric chemistry and previous intercomparison measurements for HCHO, with special reference to the diffusion scrubber Hantzsch reaction based fluorescence instrument used in the field studies reported herein. Then we discuss summertime HCHO levels in five major U.S. cities measured ove... | ['Air Pollutants', 'Cities', 'Diffusion', 'Disinfectants', 'Environmental Monitoring', 'Formaldehyde', 'Seasons', 'United States'] | 16,053,074 | [['D27.888.284.101'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['G01.202', 'G02.196'], ['D27.505.954.122.425', 'D27.720.274'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.047.407'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['Z01.107.567.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Nutrients budget and effluents characteristics in polyculture of scampi (Macrobrachium rosenbergii) and Indian major carps ponds using organic inputs. | Experiments were conducted for the study of nutrient budget in farmers' ponds (0.4-0.6 ha) in Orissa, India, at stocking densities of 0.30-0.38/m(2) for scampi (Macrobrachium rosenbergii) and 0.60-0.70/m(2) for Indian major carps (Catla catla, Labeo rohita and Cirrhinus mrigala). The average initial body weights of sca... | ['Animals', 'Aquaculture', 'Carps', 'Nitrogen', 'Palaemonidae', 'Phosphorus'] | 22,864,442 | [['B01.050'], ['J01.040.168'], ['B01.050.150.900.493.200.244.248'], ['D01.268.604', 'D01.362.625'], ['B01.050.500.131.365.190.615'], ['D01.268.666']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Staining of the calcification front in human bone using contrasting fluorochromes in vitro. | Histological studies on bone from the human iliac crest have suggested that if the customary techniques of labeling in vivo with certain fluorochromes such as tetracycline are replaced or augmented by simple whole tissue staining in vitro using the same reagents, differences in the pattern of extracellular fluorescence... | ['Bone Diseases', 'Bone and Bones', 'Calcification, Physiologic', 'Fluorescent Dyes', 'Humans', 'Ilium', 'Staining and Labeling'] | 6,209,330 | [['C05.116'], ['A02.835.232', 'A10.165.265'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825.434'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.2... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical profile, cytogenetics and treatment outcomes of adult acute myeloid leukemia. | Introduction and Aims: Acute myeloid leukemia (AML) in adults has poor prognosis. The epidemiologic profile of patients varies greatly in different geographic locations and so do the cytogenetic abnormalities and the FAB subtype of the AML. We intended to study the clinical profile, cytogenetics, and outcomes with stan... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bone Marrow', 'Chromosome Aberrations', 'Female', 'Humans', 'India', 'Induction Chemotherapy', 'Karyotyping', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Retrospective Studies', 'Treatment Outcome', 'Young Adult'] | 32,362,604 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A15.382.216'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E02.319.499', 'E02.860.500'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.4... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Carriage of multiple ribotypes of non-encapsulated Haemophilus influenzae in aboriginal infants with otitis media. | Ribotyping with the restriction enzyme XbaI was used to study the dynamics of Carriage of non-encapsulated Haemophilus influenzae (NCHi) in Aboriginal infants at risk of otitis media. Carriage rates of NCHi in the infants in the community were very high; the median age for detection was 50 days and colonization was vir... | ['Bacterial Typing Techniques', 'Haemophilus influenzae', 'Humans', 'Infant', 'Infant, Newborn', 'Nasopharynx', 'Northern Territory', 'Oceanic Ancestry Group', 'Otitis Media', 'Retrospective Studies'] | 8,620,909 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A04.623.557', 'A14.724.557'], ['Z01.639.100.875', 'Z01.678.100.373.875'], ['M01.686.508.600'], ['C09.218.705.663'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The effect of a high protein diet on leucine and alanine turnover in acid maltase deficiency. | Leucine and alanine production rate was measured in 5 patients with acid maltase deficiency in the postabsorptive state, following 6 months on a normal diet with placebo and 6 months on an isocaloric high protein diet (16-22% protein). Whole body leucine production rate, a measure of protein degradation, expressed in t... | ['Adult', 'Alanine', 'Clinical Trials as Topic', 'Dietary Proteins', 'Female', 'Follow-Up Studies', 'Glucan 1,4-alpha-Glucosidase', 'Glucose Tolerance Test', 'Glycogen Storage Disease Type II', 'Humans', 'Lactates', 'Lactic Acid', 'Leucine', 'Male', 'Middle Aged', 'Random Allocation', 'alpha-Glucosidases'] | 2,507,747 | [['M01.060.116'], ['D12.125.042'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D08.811.277.450.420.375'], ['E01.370.225.124.100.355', 'E01.37... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
The Zahn drawings: new illustrations of Xenopus | The embryos and tadpoles of the frog Xenopus are increasingly important subjects for studies of the development of the head and face - studies that are providing novel and crucial insight into the causes and prevention of a suite of devastating birth defects, as well as basic evolutionary and developmental biology. How... | ['Animals', 'Embryo, Nonmammalian', 'Face', 'Larva', 'Metamorphosis, Biological', 'Skull', 'Xenopus'] | 28,765,211 | [['B01.050'], ['A13.350', 'A16.331'], ['A01.456.505'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G07.345.500.550'], ['A02.835.232.781'], ['B01.050.150.900.090.180.610.500']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ventilatory response to isocapnic hypoxia in parents of victims of sudden infant death syndrome. | Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 +/- 46.4, while SIDS parents had a significantly lower value of 64.4 ... | ['Carbon Dioxide', 'Humans', 'Oxygen', 'Parents', 'Partial Pressure', 'Respiration', 'Respiratory Function Tests', 'Sudden Infant Death'] | 6,804,185 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.185.550', 'D01.362.670'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['G01.374.715.714'], ['G09.772.705'], ['E01.370.386.700'], ['C23.550.260.322.625', 'C23.550.260.657.500']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The genome of molluscum contagiosum virus: analysis and comparison with other poxviruses. | Analysis of the molluscum contagiosum virus (MCV) genome revealed that it encodes approximately 182 proteins, 105 of which have direct counterparts in orthopoxviruses (OPV). The corresponding OPV proteins comprise those known to be essential for replication as well as many that are still uncharacterized, including 2 of... | ['Amino Acid Sequence', 'Animals', 'Apoptosis', 'Base Sequence', 'Cells', 'Consensus Sequence', 'Conserved Sequence', 'DNA, Viral', 'Genes, Viral', 'Genome, Viral', 'Humans', 'Inclusion Bodies, Viral', 'Molecular Sequence Data', 'Molluscum contagiosum virus', 'Open Reading Frames', 'Oxidation-Reduction', 'Phylogeny', '... | 9,201,214 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G04.146.954.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11'], ['G02.111.570.580.175'], ['G02.111.570.580'], ['D13.444.308.568'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['G05.360.340.358.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The different expression profiles of microRNAs in elderly and young human dental pulp and the role of miR-433 in human dental pulp cells. | As a kind of endogenous noncoding small RNA, MicroRNA (miRNA) plays important roles of regulation to various physiological functions, while its affections on senescence of human dental pulp cell (HDPCs) are still unknown. Thus, we identified the senescence-associated miRNAs in HDPCs by microarray analysis, predicted th... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Apoptosis', 'Cell Proliferation', 'Cells, Cultured', 'Cellular Senescence', 'Dental Pulp', 'Gene Expression Regulation', 'Humans', 'MAP Kinase Signaling System', 'Male', 'MicroRNAs'] | 25,778,413 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G04.043'], ['A14.549.167.900.260'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D13.150.650.319', 'D... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
1H NMR studies of glucose transport in the human brain. | The difference between 1H nuclear magnetic resonance (NMR) spectra obtained from the human brain during euglycemia and during hyperglycemia is depicted as well-resolved glucose peaks. The time course of these brain glucose changes during a rapid increase in plasma glucose was measured in four healthy subjects, aged 18-... | ['Adolescent', 'Adult', 'Biological Transport', 'Blood Glucose', 'Blood-Brain Barrier', 'Brain', 'Extracellular Space', 'Glucose', 'Humans', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Models, Biological', 'Osmolar Concentration', 'Protons', 'Time Factors', 'Tissue Distribution'] | 8,621,747 | [['M01.060.057'], ['M01.060.116'], ['G03.143'], ['D09.947.875.359.448.500'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['A10.082.500', 'A11.284.295'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['E05.599.395'], ['G02.640'], ['D01... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Non-voluntary sterilization. | We cannot easily condemn in principle a policy where people are non-voluntarily sterilized with their informed consent (where they accept sterilization, if they do, in order to avoid punishment). There are conceivable circumstances where such a policy would be morally acceptable. One such conceivable circumstance is th... | ['Eugenics', 'Female', 'Genetics', 'Humans', 'Informed Consent', 'Intellectual Disability', 'Male', 'Philosophy, Medical', 'Sterilization, Involuntary'] | 16,920,694 | [['K01.400.307'], ['H01.158.273.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['K01.752.667'], ['E04.950.599.450', 'I01.880.604.528.750']] | ['Humanities [K]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Rapid detection of bovid herpes virus 1 antigens by counter immunoelectrophoresis and agar-gel immunodiffusion. | Using hyperimmune rabbit sera to BHV1, ID and CIEP tests detected one antigen in BHV1 infected cell culture harvests. In nasal and ocular secretions collected from experimentally infected cattle during the early course of clinical disease two and one BHV1 antigens were detected by the ID and CIEP tests respectively. In... | ['Animals', 'Antigens, Viral', 'Cattle', 'Counterimmunoelectrophoresis', 'Eye', 'Herpesvirus 1, Bovine', 'Immunodiffusion', 'Infectious Bovine Rhinotracheitis', 'Male', 'Nasal Mucosa'] | 2,540,574 | [['B01.050'], ['D23.050.327'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.225.812.735.645.350.350.150', 'E05.196.401.568.250', 'E05.200.812.735.645.350.350.150', 'E05.301.300.568.250', 'E05.478.594.760.645.350.350.150', 'E05.478.605.492.350.350.150'], ['A01.456.505.420', 'A09.371'], ['B04.280.382.100.900.400'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anterior cingulate cortex involved in social food-foraging decision-making strategies of rats. | INTRODUCTION: Decision making as a complex cognitive process involves assessing risk, reward, and costs. Typically, it has been studied in nonsocial contexts. We have developed a novel laboratory model used with rodents to detect food-foraging decision-making strategies in different social settings. However, the brain ... | ['Animals', 'Behavior, Animal', 'Decision Making', 'Feeding Behavior', 'Gyrus Cinguli', 'Kainic Acid', 'Male', 'Models, Animal', 'Rats', 'Rats, Sprague-Dawley', 'Social Behavior'] | 29,075,556 | [['B01.050'], ['F01.145.113'], ['F02.463.785.373'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['D03.383.773.400'], ['E05.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['F01.145.813']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts. | BACKGROUND: Youth in southern Africa, particularly adolescent girls and young women, are a key population for HIV prevention interventions. Untreated genital tract infections (GTIs) increase both HIV transmission and acquisition risks. South African GTI treatment guidelines employ syndromic management, which relies on ... | ['Adolescent', 'Africa, Southern', 'Candidiasis', 'Chlamydia Infections', 'Female', 'Gonorrhea', 'HIV Infections', 'Herpes Simplex', 'Humans', 'Male', 'Reproductive Tract Infections', 'Sexually Transmitted Diseases', 'South Africa', 'Syphilis', 'Trichomonas Infections', 'Trichomonas Vaginitis', 'Vaginosis, Bacterial', ... | 30,285,705 | [['M01.060.057'], ['Z01.058.290.175'], ['C01.150.703.160'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['C01.150.252.400.625.275', 'C01.150.252.734.401', 'C01.221.812.281.401', 'C01.778.281.401', 'C12.294.668.281.401', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
History of endoscopic skull base surgery: its evolution and current reality. | The history of the endoscope exemplifies the manner in which technological advances influence medicine and surgery. Endoscopic systems have evolved and improved, and they currently provide detailed visualization of a variety of deep organ structures. Otorhinolaryngological surgeons have used the endoscope for more than... | ['Endoscopy', 'Equipment Design', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Medicine', 'Neurology', 'Neurosurgical Procedures', 'Otolaryngology', 'Skull Base', 'Specialization'] | 17,639,897 | [['E01.370.388.250', 'E04.502.250'], ['E05.320'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['H02.403.600'], ['E04.525'], ['H02.403.810.526'], ['A01.456.830', 'A02.835.232.781.750'], ['H02.811']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the temporal requirement for eda in hair and sweat gland development. | EDA signaling is important in skin appendage initiation. Its possible involvement in appendage subtype determination and postinduction stage appendage development, however, has not been studied systematically. To address these issues we manipulated Eda-A1 transgene expression in a tetracycline-regulated conditional mou... | ['Animals', 'Doxycycline', 'Ectodysplasins', 'Female', 'Hair Follicle', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Signal Transduction', 'Sweat Glands', 'Transgenes'] | 18,923,450 | [['B01.050'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['D12.644.276.374.750.186', 'D12.776.395.550.275', 'D12.776.467.374.750.186', 'D12.776.543.550.275', 'D23.529.374.750.186'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serological analysis of antigenic heterogeneity of Giardia lamblia variant surface proteins. | Neonatal ZU.ICR mice were infected with trophozoites of Giardia lamblia clone GS/M-83-H7 expressing the variant surface protein (VSP) H7 and were subsequently investigated for their serum antibody response directed against VSPH7. Recombinant polypeptides, representing overlapping segments of VSPH7, and native Giardia p... | ['Animals', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Antigens, Surface', 'Giardia lamblia', 'Mice', 'Mice, Inbred ICR', 'Protozoan Proteins'] | 8,606,105 | [['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['D23.050.301'], ['B01.237.385.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['D12.776.820']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of insulin on ketogenesis and fatty acid synthesis in rat hepatocytes incubated with dichloroacetate. | In parenchymal liver cells isolated from fed rats, insulin increased the formation of 14CO2 from [1-14C]pyruvate (and presumably the flux through pyruvate dehydrogenase) by 14%. Dichloroacetate, an activator of the pyruvate dehydrogenase complex, stimulated this process by 133%. As judged from the conversion of [2-14C]... | ['Acetates', 'Acetyl Coenzyme A', 'Animals', 'Carbon Dioxide', 'Citrates', 'Citric Acid', 'Dichloroacetic Acid', 'Enzyme Activation', 'Fatty Acids', 'Female', 'Insulin', 'Ketone Bodies', 'Liver', 'Pyruvate Dehydrogenase Complex', 'Pyruvates', 'Pyruvic Acid', 'Rats', 'Rats, Inbred Strains'] | 3,918,587 | [['D02.241.081.018', 'D10.251.400.045'], ['D03.633.100.759.646.138.382.300.020', 'D08.211.211.300.075', 'D13.695.667.138.382.300.020', 'D13.695.827.068.382.300.020'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D02.241.081.901.434'], ['D02.241.081.901.434.249'], ['D02.241.081.018.214.500', 'D02.45... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel peptide specifically targeting the vasculature of orthotopic colorectal cancer for imaging detection and drug delivery. | Colorectal cancer (CRC) is the third most common malignancy and the fourth most frequent cause of cancer deaths worldwide. Ligand-mediated diagnosis and targeted therapy would have vital clinical applications in cancer treatment. In this study, an orthotopic model of colorectal cancer was established in mice. In vivo p... | ['Amino Acid Sequence', 'Animals', 'Cell Line, Tumor', 'Colorectal Neoplasms', 'Drug Carriers', 'Fluorescein', 'Fluorescein-5-isothiocyanate', 'Humans', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Microscopy, Fluorescence', 'Peptide Library', 'Peptides'] | 20,854,857 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D26.255.260', 'E02.319.300.380'], ['D02.455.426.779.347.390', 'D03.633.300.9... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparative response assessment by serum immunoglobulin M M-protein and total serum immunoglobulin M after treatment of patients with Waldenstr?m macroglobulinemia. | Serum immunoglobulin (Ig) M monoclonal protein determined by electrophoresis (sIgM-MP) and total serum IgM (sIgM) by nephelometry are widely used for response assessment in Waldenstr?m macroglobulinemia (WM), although have not been compared for predicting changes in underlying disease burden. We, therefore, compared th... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Blood Protein Electrophoresis', 'Humans', 'Immunoglobulin M', 'Middle Aged', 'Treatment Outcome', 'Waldenstrom Macroglobulinemia'] | 23,664,027 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E01.370.225.124.100.110', 'E05.196.401.076', 'E05.200.124.100.110', 'E05.301.300.049'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Backbone, side chain and heme resonance assignments of cytochrome OmcF from Geobacter sulfurreducens. | Gene knockout studies on Geobacter sulfurreducens (Gs) cells showed that the outer membrane cytochrome OmcF is involved in respiratory pathways leading to the extracellular reduction of Fe(III) citrate and U(VI) oxide. In addition, microarray analysis of OmcF-deficient mutant versus the wild-type strain revealed that m... | ['Bacterial Proteins', 'Cytochromes', 'Geobacter', 'Heme', 'Nitrogen Isotopes', 'Protein Structure, Secondary', 'Proton Magnetic Resonance Spectroscopy'] | 25,939,275 | [['D12.776.097'], ['D08.244', 'D12.776.422.220'], ['B03.440.425.410.430', 'B03.660.125.305'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D01.268.604.500', 'D01.362.625.500', 'D01.496.586'], ['G02.111.570.820.709.600'], ['E05.196.867.519.775']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurotoxic effects of bites by the Egyptian cobra (Naja haje) in Nigeria. | Two patients were bitten by Egyptian cobra (Naja haje). One became drowsy and developed transient ptosis 24 hours later. The other lost consciousness and died within two hours of the bite, but no cause was revealed by autopsy. A third patient developed severe transient neurological signs after being bitten by an uniden... | ['Adolescent', 'Animals', 'Antivenins', 'Autopsy', 'Child', 'Female', 'Humans', 'Male', 'Nigeria', 'Snake Bites', 'Snake Venoms'] | 1,265,823 | [['M01.060.057'], ['B01.050'], ['D12.776.124.486.485.114.573.601.138', 'D12.776.124.790.651.114.573.601.138', 'D12.776.377.715.548.114.573.601.138', 'D20.215.401.601.163'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.190.565'], ['C25... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Eye movement during reading in young adults with cerebral palsy measured with eye tracking. | BACKGROUND: Cerebral palsy is a nonprogressive brain disorder associated with lifelong motor impairments and often with cognitive deficits, impaired communication, and impaired sensory perception. Vision deficits, in particular, occur frequently in cerebral palsy and can lead to reading difficulties.OBJECTIVE: Investig... | ['Adult', 'Cerebral Palsy', 'Eye Movements', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reading', 'Saccades', 'Time Factors'] | 25,295,659 | [['M01.060.116'], ['C10.228.140.140.254'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['L01.559.423.557'], ['G14.350.500'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Recombinant human growth hormone improves muscle amino acid uptake and whole-body protein metabolism in chronic hemodialysis patients. | BACKGROUND: Intradialytic parenteral nutrition (IDPN), with or without exercise, has been shown to reverse the net negative whole-body and forearm muscle protein balances observed during hemodialysis. Pharmacologic doses of recombinant human growth hormone (rhGH) constitute another potential anabolic therapy in chronic... | ['Adult', 'Amino Acids', 'Carbon Isotopes', 'Cross-Over Studies', 'Energy Metabolism', 'Exercise', 'Female', 'Human Growth Hormone', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Muscle, Skeletal', 'Oxidation-Reduction', 'Oxygen Consumption', 'Parenteral Nutrition', 'Proteins', 'Recombinant Proteins', 'Renal Dialysis',... | 16,332,656 | [['M01.060.116'], ['D12.125'], ['D01.268.150.075', 'D01.496.123'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G03.295'], ['G11.427.410.698.277', 'I03.350'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The DAI prospective study on macrovascular complications in patients with type 2 diabetes. Characteristics of the study population. | A large multicenter cohort study, the DAI study, is being performed on patients with type 2 diabetes mellitus who are followed by diabetic care units in Italy, to study the prevalence and incidence of myocardial infarction, ischemic heart disease, coronary artery bypass, coronary angioplasty, cerebral thromboembolism, ... | ['Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies'] | 11,758,287 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dual representation of the hand in the cerebellum: activation with voluntary and passive finger movement. | Early electrophysiological studies during sensory stimulation in the anesthetized cat and more recent functional imaging studies during voluntary movement in humans have provided evidence for two separate representations of the body in the anterior and posterior lobes of the cerebellum; however, the functional role of ... | ['Adult', 'Brain Mapping', 'Cerebellar Cortex', 'Echo-Planar Imaging', 'Female', 'Fingers', 'Hand', 'Humans', 'Image Processing, Computer-Assisted', 'Isometric Contraction', 'Kinesthesis', 'Magnetic Resonance Imaging', 'Male', 'Motor Activity', 'Range of Motion, Articular'] | 12,667,844 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132.810.428.200.212'], ['E01.370.350.825.500.200'], ['A01.378.800.667.430'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G11.427.494.472'], ['F02.830.816.541.504', 'G11... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Modification of a nonrebreathing circuit adapter to prevent barotrauma in anesthetized patients. | Barotrauma, pneumothorax, and pneumomediastinum occurred in two anesthetized cats in which the waste gas outlet of a nonrebreathing circuit was occluded. To prevent any similar cases of barotrauma, we have modified our nonrebreathing circuit adapters by inserting a 15 cm H2O PEEP valve into the gas pathway of the nonre... | ['Anesthesia', 'Anesthesiology', 'Animals', 'Barotrauma', 'Cat Diseases', 'Cats', 'Female', 'Intestinal Diseases', 'Male', 'Mediastinal Emphysema', 'Pneumothorax', 'Positive-Pressure Respiration', 'Respiration'] | 7,571,388 | [['E03.155'], ['H02.403.066'], ['B01.050'], ['C26.120'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C06.405.469'], ['C08.846.187.290', 'C23.550.325.250'], ['C08.528.778'], ['E02.041.625.790', 'E02.880.820.790'], ['G09.772.705']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Pulmonary changes in rheumatoid arthritis]. | A 78-year-old smoker with a medical history of rheumatoid arthritis (RA) diagnosed 23 years before death and treated for 10 years by sulfasalazine followed by 7 years of therapy by purine antimetabolite (AZAMUN, Leiras Co.). Two years before his death chemotherapy was added to treat a low grade malignant lymphoma. Pulm... | ['Aged', 'Arthritis, Rheumatoid', 'Humans', 'Lung Diseases', 'Male', 'Ossification, Heterotopic'] | 11,669,018 | [['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['C23.550.751']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of multiplex ligation dependent probe amplification to immunohistochemistry for assessing HER-2/neu amplification in invasive breast cancer. | The HER-2/neu transmembrane tyrosine kinase receptor is both a prognostic marker and a therapeutic target for breast cancer. Accurate determination of HER-2/neu status is a prerequisite for selecting breast tumors for HER-2/neu immunotherapy or for taxan based chemotherapy. Unfortunately, there is no consensus concerni... | ['Breast Neoplasms', 'Female', 'Gene Amplification', 'Humans', 'Immunohistochemistry', 'Molecular Probes', 'Polymerase Chain Reaction', 'Receptor, ErbB-2'] | 16,908,432 | [['C04.588.180', 'C17.800.090.500'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk factors for adenomyosis. | In order to analyse risk factors for adenomyosis, 707 consecutive women who underwent hysterectomy between January 1993 and June 1994 at the Clinica Luigi Mangiagalli, Milan, Italy, were interviewed before surgery by trained physicians. Information on the presence of adenomyosis was obtained from pathologic records. Ou... | ['Abortion, Spontaneous', 'Adult', 'Endometriosis', 'Female', 'Humans', 'Hysterectomy', 'Italy', 'Middle Aged', 'Odds Ratio', 'Parity', 'Pregnancy', 'Risk Factors', 'Smoking'] | 9,222,017 | [['C13.703.039', 'G08.686.784.769.496.125'], ['M01.060.116'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['Z01.542.489'], ['M01.060.116.630'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.830.600.600'], ['G08.686.677', 'G08.686.784.769.47... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Drug metabolism in adult white leghorn hens--response to enzyme inducers. | 1. Adult hens were given a mixture of polychlorinated biphenyls (0.5 and 2 g/kg Aroclor 1254), 3-methylcholanthrene (80 mg/kg) or beta-napthoflavone (80 mg/kg). 2. beta-Napthoflavone elevated activities of both microsomal and nonmicrosomal enzymes 48 hr after dosing, with cytochrome P-450 p-nitroanisole O-demethylase, ... | ['Aniline Hydroxylase', 'Animals', 'Aroclors', 'Benzoflavones', 'Chickens', 'Chlorodiphenyl (54% Chlorine)', 'Cytochrome P-450 Enzyme System', 'Flavonoids', 'Glutathione Transferase', 'Male', 'Methylcholanthrene', 'Mice', 'Microsomes, Liver', 'Oxidoreductases, O-Demethylating', 'Polychlorinated Biphenyls', 'Rats', 'bet... | 6,133,690 | [['D08.244.453.005.050', 'D08.811.682.690.708.170.010.050', 'D12.776.422.220.453.010.050'], ['B01.050'], ['D02.309.750.500', 'D02.455.526.439.773.292', 'D02.455.526.439.785.292'], ['D03.383.663.283.266.450.175', 'D03.633.100.150.266.450.175'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D02.309.75... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of prostacyclin in the response of cerebral blood flow to CO2. | The prostacyclin (PGI2) formation in cerebral vessels, as reflected by the difference in concentration of internal carotid arterial and internal jugular venous radioimmunoassayed 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), was determined under normocapnic and hypercapnic conditions in 5 patients with mild cerebr... | ['6-Ketoprostaglandin F1 alpha', 'Aged', 'Brain', 'Carbon Dioxide', 'Cerebrovascular Circulation', 'Epoprostenol', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oxygen', 'Prostaglandins'] | 6,402,270 | [['D10.251.355.255.550.400.350', 'D10.251.355.325.450', 'D23.469.050.175.725.400.350'], ['M01.060.116.100'], ['A08.186.211'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G09.330.100.159'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Protaper--hybrid technique. | UNLABELLED: Crown down preparation is the most known and described technique since the introduction of Nickel Titanium (NiTi) rotary instruments in endodontics. This technique gives good results but has limitations, such as not addressing the initial anatomy of oval or dumb-bell shaped canals. The specific design of th... | ['Dental Alloys', 'Dental Instruments', 'Dental Pulp Cavity', 'Humans', 'Nickel', 'Root Canal Preparation', 'Titanium'] | 18,426,164 | [['D25.339.208', 'J01.637.051.339.208'], ['E06.186.501', 'E07.222.501'], ['A14.549.167.900.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['E06.397.778.889', 'E06.931.625'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Improvement of plateletpheresis via technical modification on the MCS+. | BACKGROUND: With the advantage of easy operation and high reliability, Haemonetics multicomponent collection system (MCS+) is widely used as a blood cell separator in clinical application.OBJECTIVES: The aim of this study was to evaluate the effect of technical parameter modification as utilised on the MCS+ to improve ... | ['Blood Donors', 'Female', 'Humans', 'Male', 'Plateletpheresis'] | 26,074,299 | [['M01.898.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.160.790', 'E02.120.285.790', 'E05.200.500.363.171.790', 'E05.242.363.171.790']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antiviral effects of Phyllanthus urinaria containing corilagin against human enterovirus 71 and Coxsackievirus A16 in vitro. | Human enterovirus 71 (EV71) and Coxsackievirus A16 (CA16) are major causative agents of hand, foot, and mouth disease (HFMD) especially in infants and children under 5 years of age. Despite recent outbreaks of HFMD, there are no approved therapeutics against EV71 and CA16 infection. Moreover, in a small percentage of c... | ['Animals', 'Antiviral Agents', 'Cell Survival', 'Chlorocebus aethiops', 'Cytopathogenic Effect, Viral', 'Dose-Response Relationship, Drug', 'Enterovirus A, Human', 'Epithelial Cells', 'Glucosides', 'Hydrolyzable Tannins', 'Phyllanthus', 'Plant Components, Aerial', 'Plant Extracts', 'Vero Cells'] | 24,752,860 | [['B01.050'], ['D27.505.954.122.388'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['G07.690.773.875', 'G07.690.936.500'], ['B04.820.578.750.284.180'], ['A11.436'], ['D09.408.348'], ['D02.241.223.100.300.200.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. | Adiponectin is an adipocyte-secreted protein involved in a variety of metabolic processes, including glucose regulation and fatty acid catabolism. We conducted a genome-wide association study to investigate the genetic loci associated with plasma adiponectin in 1776 unrelated Filipino women from the Cebu Longitudinal H... | ['Adiponectin', 'Adult', 'Cadherins', 'Female', 'Genetic Loci', 'Genome-Wide Association Study', 'Haplotypes', 'Humans', 'Kininogen, High-Molecular-Weight', 'Kininogen, Low-Molecular-Weight', 'Kininogens', 'Longitudinal Studies', 'Mothers', 'Nutrition Surveys', 'Philippines', 'Polymorphism, Single Nucleotide', 'Quantit... | 20,876,611 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['M01.060.116'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['G05.360.340.024.380'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Comparative study of 2 dosages of low molecular weight heparin, PK 10169, in the prevention of thromboembolic incidents during treatment of 103 femur neck fractures]. | Results of this study in the elderly with fractures of femoral neck, in whom their exists an enhanced thrombogenic risk, showed that the dose of 40 mg per 24 hours as one or two divided injections of enoxaparine was as effective as adapted subcutaneous doses of calcium heparinate. It was also less iatrogenic and easier... | ['Aged', 'Aged, 80 and over', 'Drug Administration Schedule', 'Female', 'Femoral Neck Fractures', 'Heparin, Low-Molecular-Weight', 'Humans', 'Male', 'Postoperative Complications', 'Thromboembolism'] | 2,834,501 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.319.283'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['D09.698.373.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['C14.907.355.590']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of hyperthyroidism on hand grip strength and function. | Hyperthyroidism is a pathologic condition in which the body is exposed to excessive amounts of circulating thyroid hormones. Skeletal muscle is one of the major target organs of thyroid hormones. We evaluated hand grip strength and function in patients with overt hyperthyroidism. Fifty-one patients newly diagnosed with... | ['Adult', 'Aged', 'Case-Control Studies', 'Female', 'Hand', 'Hand Strength', 'Humans', 'Hyperthyroidism', 'Male', 'Middle Aged', 'Motor Skills'] | 26,562,373 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A01.378.800.667'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['M01.060.116.630'], ['F02.808.260']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Where should obstetric vesico-vaginal fistulas be repaired: at the district general hospital or a specialized fistula center? | Expanded surgical capacities are required to treat obstetric fistulas. Achieving a balance between relative ease of access to services and use of the appropriate clinical setting is difficult. This article asks, "Are obstetric fistulas best repaired locally, at the district hospital where more women would have greater ... | ['Delivery of Health Care', 'Developing Countries', 'Female', 'Gynecologic Surgical Procedures', 'Health Services', 'Hospitals', 'Hospitals, District', 'Hospitals, General', 'Hospitals, Special', 'Humans', 'Obstetric Labor Complications', 'Pregnancy', 'Urogenital Surgical Procedures', 'Vesicovaginal Fistula'] | 17,727,855 | [['N04.590.374', 'N05.300'], ['I01.615.500.300'], ['E04.950.300'], ['N02.421'], ['N02.278.421'], ['N02.278.421.510.140'], ['N02.278.421.389'], ['N02.278.421.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.420'], ['G08.686.784.769'], ['E04.950'], ['C13.351.500.894.767.500', 'C13.351.875.881.312.733', '... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Uncertainty in model predictions of Vibrio vulnificus response to climate variability and change: a Chesapeake Bay case study. | The effect that climate change and variability will have on waterborne bacteria is a topic of increasing concern for coastal ecosystems, including the Chesapeake Bay. Surface water temperature trends in the Bay indicate a warming pattern of roughly 0.3-0.4°C per decade over the past 30 years. It is unclear what impact ... | ['Bays', 'Climate', 'Climate Change', 'Delaware', 'Ecosystem', 'Maryland', 'Models, Theoretical', 'Salinity', 'Temperature', 'Uncertainty', 'Vibrio vulnificus', 'Virginia', 'Water Microbiology'] | 24,874,082 | [['G01.311.625.080'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.175.374'], ['Z01.107.567.875.500.200'], ['G16.500.275.157', 'N06.230.124'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['E05.599'], ['G02.640.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Focal neuropathies following percutaneous nephrolithotomy (PCNL)--preliminary study. | INTRODUCTION: Postoperative neurological complications in pelvic and renal surgery are a well-known clinical problem and their morbidities are important. We designed this study to determine prevalence and risk factors of such complications after percutaneous nephrolithotomy (PCNL) surgery.MATERIAL AND METHODS: A cross-... | ['Comorbidity', 'Female', 'Humans', 'Incidence', 'Iran', 'Male', 'Middle Aged', 'Nephrostomy, Percutaneous', 'Peripheral Nerve Injuries', 'Peripheral Nervous System Diseases', 'Pilot Projects', 'Postoperative Complications', 'Risk Factors'] | 23,798,911 | [['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.252.245.500.350'], ['M01.060.116.630'], ['E01.370.390.550', 'E04.579.642', 'E04.950.774.739.500', 'E04.950.774... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ligand sensitivity in dimeric associations of the serotonin 5HT2c receptor. | G-protein-coupled receptors (GPCRs) respond to external stimuli by activating heterotrimeric G proteins inside the cell. There is increasing evidence that many GPCRs exist as dimers or higher oligomers, but the biochemical nature of such dimers and what roles they have, if any, in signal transduction remains unclear. W... | ['Cell Line', 'Cysteine', 'Dimerization', 'Humans', 'Immunoblotting', 'Immunoprecipitation', 'Ligands', 'Models, Molecular', 'Mutagenesis', 'Protein Structure, Tertiary', 'Receptor, Serotonin, 5-HT2C'] | 18,344,975 | [['A11.251.210'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G02.206', 'G03.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['E05.196.150.639', 'E05.478.605'], ['D27.720.470.480'], ['E05.599.595'], ['G05.558'], ['G02.111.570.820.709.61... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The genome of the Pseudomonas aeruginosa generalized transducing bacteriophage F116. | F116 is a temperate, pilus-specific, generalized transducing phage belonging to the Podoviridae virus family. Its genome is linear, ds, TR, and CP DNA with a GC content of 63.2%. The 65 195-bp genome contains 70 putative ORFs, only 16 of which showed sequence similarity to Pseudomonas genomic or phage genes. While the ... | ['Bacteriophages', 'DNA Replication', 'Electrophoresis, Polyacrylamide Gel', 'Evolution, Molecular', 'Genome, Bacterial', 'Plasmids', 'Pseudomonas aeruginosa', 'Recombination, Genetic', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 15,716,012 | [['B04.123'], ['G02.111.225', 'G05.226'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.358.207'], ['G05.360.600'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['G05.728'], ['E05.196.566.755']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dating couples' attachment styles and patterns of cortisol reactivity and recovery in response to a relationship conflict. | This study investigated theoretically predicted links between attachment style and a physiological indicator of stress, salivary cortisol levels, in 124 heterosexual dating couples. Cortisol was assessed at 7 points before and after an experimental conflict negotiation task, creating a trajectory of stress reactivity a... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Affect', 'Conflict, Psychological', 'Courtship', 'Female', 'Humans', 'Hydrocortisone', 'Linear Models', 'Male', 'Massachusetts', 'Models, Psychological', 'Multivariate Analysis', 'Negotiating', 'Object Attachment', 'Saliva', 'Sex Factors', 'Stress, Psychological'] | 16,649,858 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['F01.658.209'], ['F01.145.802.279'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.75... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Functional site of human placental estradiol 17 beta-dehydrogenase involves tyrosine residues, as evidenced by reaction to p-nitrobenzenesulfonyl fluoride. | Native estradiol 17 beta-dehydrogenase (EC 1.1.1.62) from human placenta was inactivated in time dependent manner by p-nitrobenzenesulfonyl fluoride (NBSF), which is a reagent for chemical modification of tyrosine. The sulfhydryl-blocked enzyme by 5,5'-dithio-bis(2-nitrobenzoic acid) (DTNB) was also reacted with NBSF m... | ['17-Hydroxysteroid Dehydrogenases', 'Binding Sites', 'Dithionitrobenzoic Acid', 'Dithiothreitol', 'Estradiol Dehydrogenases', 'Female', 'Humans', 'Kinetics', 'Nitrobenzenes', 'Placenta', 'Pregnancy', 'Protein Binding', 'Tyrosine'] | 6,580,514 | [['D08.811.682.047.436.375'], ['G02.111.570.120'], ['D02.241.223.100.600.300', 'D02.455.426.559.389.127.650.300'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['D08.811.682.047.436.375.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D02.455.426.559.389.565', 'D02.640... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical analysis and comparison of napsin A, TTF1, SPA and CK7 expression in primary lung adenocarcinoma. | We investigated the expression of napsin A, TTF1, SPA and CK7 in primary lung adenocarcinoma (ADC) and compared antibody specificity and sensitivity. We used immunohistochemistry (IHC) using antibodies directed against napsin A, TTF1, SPA, and CK7 on cancer tissue from 454 patients diagnosed with lung cancer. In primar... | ['Adenocarcinoma of Lung', 'Adult', 'Aged', 'Aged, 80 and over', 'Aspartic Acid Endopeptidases', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'DNA-Binding Proteins', 'Female', 'Humans', 'Immunohistochemistry', 'Keratin-7', 'Lung', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Pulmonary Surfactant-Associated Proteins', ... | 29,956,575 | [['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Methicillin-resistant Staphylococcus aureus bloodstream infections in a Japanese University Hospital between 1987 and 2004. | Methicillin-resistant Staphylococcus aureus (MRSA) infections have been the most common cause of nosocomial infections in Japan, but their genetic characteristics related to bloodstream infections have not been well studied. The aim of this study was to investigate a comprehensive molecular characterization of MRSA blo... | ['Anti-Bacterial Agents', 'Bacteremia', 'Bacterial Proteins', 'Cross Infection', 'Electrophoresis, Gel, Pulsed-Field', 'Hospitals, University', 'Humans', 'Japan', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Molecular Epidemiology', 'Multilocus Sequence Typing', 'Staphylococcal Infecti... | 22,009,526 | [['D27.505.954.122.085'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['D12.776.097'], ['C01.248', 'C23.550.291.875.500'], ['E05.196.401.220', 'E05.301.300.220'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['B03... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
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