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Characteristic Assessment of Diesel-degrading Bacteria Immobilized on Natural Organic Carriers in Marine Environment: the Degradation Activity and Nutrient. | Oil spill has led to severe environmental and ecological problems. Due to the harsh environmental conditions, the bioremediation technology is not successfully used to remedy the oil spill in marine environment. In this study, immobilization technology was used to immobilize bacteria on natural organic carriers (i.e., ... | ['Aquatic Organisms', 'Bacteria', 'Biodegradation, Environmental', 'Biomass', 'Environment', 'Nitrogen', 'Petroleum', 'Phosphorus', 'Seawater', 'Water Pollution, Chemical'] | 28,819,269 | [['B05.080', 'G16.500.275.725.500.650.075'], ['B03'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G16.500.275.157.100', 'N06.230.124.100'], ['G16.500.275', 'N06.230'], ['D01.268.604', 'D01.362.625'], ['D20.345.630', 'N06.230.132.258.630'], ['D01.268.666'], ['G16.500.275.725.500'], ['N06.850.460.790.410']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Study of protein assimilation, using stable isotope techniques. | Information on the efficiency and kinetics of protein assimilation in humans is scanty and moreover controversial. This is mainly due to the lack of a reliable and non-invasive measuring technique. The recent availability of stable isotope labelled protein allowed to study protein assimilation using tracer techniques. ... | ['Adult', 'Anti-Ulcer Agents', 'Breath Tests', 'Carbon Dioxide', 'Carbon Isotopes', 'Dietary Proteins', 'Egg White', 'Female', 'Gastric Acid', 'Hot Temperature', 'Humans', 'Male', 'Omeprazole', 'Pancreatic Diseases', 'Proteins', 'Reference Values', 'Trypsin'] | 10,420,947 | [['M01.060.116'], ['D27.505.954.483.203'], ['E01.370.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.268.150.075', 'D01.496.123'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.300.470.700', 'J02.500.470.700'], ['A12.200.307.603'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Postmortem delay has minimal effect on brain RNA integrity. | The Bryan Alzheimer Disease Research Center obtains postmortem human brain tissue from patients with Alzheimer disease (AD) and cognitively normal control subjects for molecular and genetic research programs. A growing body of research suggests that variations in gene transcript levels may contribute to the onset and p... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Brain', 'Female', 'Gene Expression Regulation', 'Humans', 'Male', 'Middle Aged', 'Nerve Tissue Proteins', 'Postmortem Changes', 'RNA', 'Reverse Transcriptase Polymerase Chain Reaction', 'Specimen Handling'] | 18,090,918 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.631'], ['C23.550.260.224.617'], ['D13.444.735'], ['E05.393.620.500.725'], ['E01.370.225.998', 'E05.2... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transient inhibition of the dorsolateral prefrontal cortex disrupts somatosensory modulation during standing balance as measured by electroencephalography. | Several studies have shown that a light fingertip touch on a stable surface reduces body sway for individuals standing with their eyes closed even when touch forces are too low to offer mechanical support. It has been proposed that this is due to the availability of sway-relevant sensory feedback from the hand compensa... | ['Adult', 'Electroencephalography', 'Evoked Potentials', 'Evoked Potentials, Somatosensory', 'Feedback, Sensory', 'Fingers', 'Humans', 'Neural Inhibition', 'Postural Balance', 'Prefrontal Cortex', 'Touch', 'Young Adult'] | 22,407,071 | [['M01.060.116'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['F04.754.137.301.500', 'F04.754.308.500.500', 'F04.754.339', 'G07.410.732.500'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.265.755', 'G... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autoradiographic determination of neurotransmitter receptor distributions in the cerebral and cerebellar cortices. | Light microscopic autoradiographical localization of drug and neurotransmitter receptors provides investigators with a tool to determine the sites of drug action with a high degree of anatomical resolution. In the cortex, where there is a distinct laminar organization, the differential distribution of receptors can be ... | ['Animals', 'Autoradiography', 'Cerebellar Cortex', 'Cerebral Cortex', 'Rats', 'Receptors, Adrenergic', 'Receptors, Cell Surface', 'Receptors, Drug', 'Receptors, GABA-A', 'Receptors, Histamine H1', 'Receptors, Muscarinic', 'Receptors, Neurotensin', 'Receptors, Neurotransmitter', 'Receptors, Opioid'] | 6,270,206 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A08.186.211.132.810.428.200.212'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.670.300.300', 'D12.776.543.750.695.150.300', 'D12.776.543.750.720.330.300'], ['D12.776.543.750'], ['D12.776.827'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Comparative studies on the tolerance of bioequivalent doses of intravenous methylxanthine preparations in healthy subjects]. | In a comparative tolerance study with two different intravenous methylxanthine preparations, a theophylline-ethylendiamine preparation (TE-reference preparation) was tested against a combination of theophylline, proxyphylline (7-(2-hydroxypropyl)-theophylline) and diprophylline (7-(2,3-dihydroxypropyl)-theophylline) (N... | ['Adult', 'Blood Pressure', 'Drug Tolerance', 'Dyphylline', 'Humans', 'Injections, Intravenous', 'Male', 'Pulse', 'Respiration', 'Theophylline', 'Therapeutic Equivalency', 'Time Factors', 'Xanthines'] | 4,039,588 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.690.773.992'], ['D03.633.100.759.758.824.751.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['E01.370.370.380.650', 'G09.330.380.750'], ['G09.772.705'], ['D03.132.960.751', 'D03.633.100.759.758.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The cotton tipped applicator - a scratch for the itch and more during dermatologic surgery. | An itch during surgery can be distracting. Sterile cotton tipped applicators are inexpensive and multipurpose tools that may be used for a variety of simple surgical tasks such as scratching an itch on the surgeon or patient's face. They may also be used to adjust glasses and turn on surgical lights or the electrocaute... | ['Dermatologic Surgical Procedures', 'Humans', 'Pruritus', 'Surgical Instruments'] | 30,982,312 | [['E04.680.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.685', 'C23.888.885.625'], ['E07.858.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crizotinib reduces the rate of dark adaptation in the rat retina independent of ALK inhibition. | Crizotinib (Xalkori) is a tyrosine kinase inhibitor of both anaplastic lymphoma kinase (ALK) and mesenchymal-epithelial transition factor (c-Met). Though not predicted from standard nonclinical toxicological evaluation, visual disturbance became a frequently observed adverse event in humans. To understand the possible ... | ['Administration, Oral', 'Anaplastic Lymphoma Kinase', 'Animals', 'Crizotinib', 'Dark Adaptation', 'Dogs', 'Electroretinography', 'Evoked Potentials', 'Humans', 'Immunohistochemistry', 'Light', 'Macaca fascicularis', 'Male', 'Mice', 'Photic Stimulation', 'Protein Kinase Inhibitors', 'Proto-Oncogene Proteins c-met', 'Py... | 25,326,243 | [['E02.319.267.100'], ['D08.811.913.696.620.682.725.400.002', 'D12.776.543.750.630.002'], ['B01.050'], ['D03.383.621.154', 'D03.383.725.050.263'], ['G14.020.371'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.380.225', 'E01.370.405.270'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[International Prostate Symptom Scale. Evaluation of the usefulness of a French version]. | OBJECTIVE: To evaluate the usefulness of a French-language version of the International Prostate Symptom Scale (I-PSS) by measuring, on this scale and on the quality of life index, the scores of patients with benign prostatic hyperplasia before and after prostate surgery.METHOD: The questionnaire was completed by 14 me... | ['Aged', 'Aged, 80 and over', 'Bias', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Prostatectomy', 'Prostatic Hyperplasia', 'Quality of Life', 'Quebec', 'Reproducibility of Results', 'Surveys and Questionnaires', 'Translating'] | 11,013,796 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.150', 'N06.850.490.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.950.774.860.625'], ['C12.294.565.500'], ['I01.800', 'K01.752.400.7... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Epidemiology of Down syndrome in 118,265 consecutive births. | The epidemiology of Down syndrome (DS) was studied in the area which is covered by our registry of congenital malformations. For each of the 139 new DS cases which were ascertained during the period 1979 to 1987 more than 50 factors were studied and compared to those from control infants. The prevalence of DS was 1.17%... | ['Abortion, Induced', 'Consanguinity', 'Down Syndrome', 'Fetal Death', 'France', 'Humans', 'Karyotyping', 'Parents', 'Prevalence'] | 2,149,980 | [['E04.520.050'], ['G05.090.403.180', 'G05.180'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['C13.703.223', 'C23.550.260.585'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Characterization of purified staphylococcal lipase. | Purified staphylococcal lipase had an optimal pH of 8.3 for activity at 37 C, and an optimal temperature of 45 C at pH 8.0. During storage, the enzyme lost less than 10% of the activity over a period of 21 days at 4 and -23 C. The enzyme retained 93% of the activity when heated for 30 min at 50 C and was 95% destroyed ... | ['Fats', 'Fatty Acids', 'Hydrogen-Ion Concentration', 'Lipase', 'Staphylococcus', 'Temperature'] | 6,035,042 | [['D10.212'], ['D10.251'], ['G02.300'], ['D08.811.277.352.100.400'], ['B03.300.390.400.800.750', 'B03.353.500.750.750', 'B03.510.100.750.750', 'B03.510.400.790.750'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Double mutation of two homologous genes YL1 and YL2 results in a leaf yellowing phenotype in soybean [Glycine max (L.) Merr]. | KEY MESSAGE: Two homologous, chloroplast located CAAX proteases were identified to be functional redundancy in determining soybean leaf color, and they probably play essential roles in regulating light harvesting and absorption during photosynthesis process. Leaf color mutants are ideal materials for studying photosynt... | ['Alleles', 'Base Sequence', 'Chlorophyll', 'Cloning, Molecular', 'Color', 'Gene Expression Regulation, Plant', 'Gene Knockdown Techniques', 'Gene Silencing', 'Genes, Plant', 'Mutation', 'Phenotype', 'Photosynthesis', 'Pigments, Biological', 'Plant Leaves', 'Plant Proteins', 'Seeds', 'Sequence Alignment', 'Sequence Ana... | 32,323,129 | [['G05.360.340.024.340.030'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['E05.393.220'], ['G01.590.540.199'], ['G05.308.375'], ['E05.393.335.500'], ['G05.308.203.374'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.365.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Size-dependent sex change can be the ESS without any size advantage of reproduction when mortality is size-dependent. | Almost all models of sex change evolution assume that reproductive rate increases with body size. However, size-dependent sex changing plants often show size-independent reproductive success, presumably due to pollen limitation. Can the observed size-dependent sex change pattern be the ESS in this case? To answer this ... | ['Body Size', 'Disorders of Sex Development', 'Evolution, Molecular', 'Genes, Plant', 'Mortality', 'Pollen', 'Reproduction', 'Risk Factors', 'Sex Characteristics', 'Sex Differentiation', 'Sex Ratio'] | 20,673,775 | [['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['C12.706.316', 'C13.351.875.253', 'C16.131.939.316', 'C19.391.119'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Lymph node metastases in adenoid cystic carcinoma. | The clinical characteristics of 76 patients with adenoid cystic carcinoma seen during a 22-year period are described. Lymph node metastases at presentation or later occurred almost exclusively in men, and the five-year rate of "node-free" survival was 62 per cent for men and 95 per cent for women. Node metastases were ... | ['Carcinoma, Adenoid Cystic', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Male', 'Prognosis', 'Prospective Studies'] | 3,002,198 | [['C04.557.470.200.025.220'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.789'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The polymer brush model of neurofilament projections: effect of protein composition. | Applying self-consistent field theory, we consider a coarse-grained model for the polymerlike projections of neurofilament (NF) proteins that form a brush structure around neurofilaments. We focus on effects of molecular composition, which is the relative occurrence of NF-H, NF-M, and NF-L proteins, on the organization... | ['Algorithms', 'Animals', 'Mice', 'Mice, Knockout', 'Mice, Transgenic', 'Models, Neurological', 'Mutation', 'Neurofilament Proteins', 'Phosphorylation', 'Thermodynamics'] | 20,141,760 | [['G17.035', 'L01.224.050'], ['B01.050'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['E05.599.395.642'], ['G05.365... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Arthroscopy in a complicated total knee prosthesis with suspected infection and loosening of the polypropylene "tibial insert". Case report and literature review]. | The case of a patient with a complicated total knee prosthesis with pain, impaired mobility and fever at postoperative week 8 is presented herein. Infection was suspected and the impossibility of the available means to distinguish it from "aseptic" loosening is emphasized. The problem of making a certain diagnosis was ... | ['Arthroplasty, Replacement, Knee', 'Arthroscopy', 'Diabetes Mellitus, Type 2', 'Humans', 'Knee', 'Male', 'Middle Aged', 'Polypropylenes', 'Prosthesis Failure', 'Radiography', 'Reoperation', 'Tibia', 'Time Factors', 'Treatment Outcome'] | 20,377,065 | [['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['M01.060.116.630'], ['D02.455.326.271.665.590', 'D05.750.716.550', 'D25.720.716.55... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Angiotensin II receptor blocker reduces oxidative stress and attenuates hypoxia-induced left ventricular remodeling in apolipoprotein E-knockout mice. | Elevated superoxide formation in cardiac extracts of apolipoprotein E-knockout (apoE-KO) mice has been reported. In addition, we previously reported that hypoxia increased oxidative stress in the aortas of apoE-KO mice, although we did not examine the effect of hypoxia on the heart. The aim of this study was to investi... | ['Aldehydes', 'Angiotensin II Type 1 Receptor Blockers', 'Animals', 'Apolipoproteins E', 'Heart Ventricles', 'Hypertrophy, Left Ventricular', 'Hypoxia', 'Imidazoles', 'Male', 'Matrix Metalloproteinase 9', 'Matrix Metalloproteinase Inhibitors', 'Mice', 'Mice, Knockout', 'Myocytes, Cardiac', 'NADPH Oxidases', 'NF-kappa B... | 18,344,628 | [['D02.047'], ['D27.505.519.162.500'], ['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['A07.541.560'], ['C14.280.195.400', 'C23.300.775.250.400'], ['C23.888.852.079'], ['D03.383.129.308'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.252.445', 'D08.811.277.656.300.480.52... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell growth and division. I. A mathematical model with applications to cell volume distributions in mammalian suspension cultures. | A mathematical model is formulated for the development of a population of cells in which the individual members may grow and divide or die. A given cell is characterized by its age and volume, and these parameters are assumed to determine the rate of volume growth and the probability per unit time of division or death.... | ['Animals', 'Cell Division', 'Computers', 'Culture Techniques', 'Kinetics', 'Mammals', 'Mathematics', 'Models, Biological', 'Population Growth', 'Spectrum Analysis'] | 6,069,910 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['L01.224.230.260'], ['E05.481.500'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649'], ['H01.548'], ['E05.599.395'], ['I01.240.600.660', 'N01.224.625.660', 'N06.850.505.400.700.660'], ['E05.196.867']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Configurational Statistics of Magnetic Bead Detection with Magnetoresistive Sensors. | Magnetic biosensors detect magnetic beads that, mediated by a target, have bound to a functionalized area. This area is often larger than the area of the sensor. Both the sign and magnitude of the average magnetic field experienced by the sensor from a magnetic bead depends on the location of the bead relative to the s... | ['Biosensing Techniques', 'DNA', 'Humans', 'Immunomagnetic Separation', 'Magnetic Fields', 'Magnetite Nanoparticles', 'Proteins', 'Sensitivity and Specificity'] | 26,496,495 | [['E05.601.043'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.437', 'E05.200.500.363.441', 'E05.242.363.441'], ['G01.358.750'], ['J01.637.512.600.500.144.500'], ['D12.776'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Relation of lymphatic microvessel density detected by monoclonal antibody D2-40 with VEGF-C expression in breast cancer]. | OBJECTIVE: To investigate the relationship of lymphatic micovessel density (LMVD) detected by monoclonal antibody D2-40) with the VEGF-C expression in human breast cancer.METHODS: Tissue samples of 102 breast cancers, 25 breast fibroadenomas and 10 normal breasts were collected. Immunohistochemical staining was used to... | ['Adult', 'Aged', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Murine-Derived', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Female', 'Fibroadenoma', 'Humans', 'Lymph Nodes', 'Lymphangiogenesis', 'Lymphatic Metastasis', 'Lymphatic Vessels', 'Microvessels', 'Middle Aged', 'Neoplasm Staging', 'RNA, Messenger',... | 18,953,835 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.47... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water extractable phytochemicals from some tropical spices. | CONTEXT: Spices have been used as food adjuncts and in folklore for ages. Inhibition of key enzymes (á-amylase and á-glucosidase) involved in the digestion of starch and protection against free radicals and lipid peroxidation in pancreas could be part of the therapeutic approach towards the management of hyperglycemia ... | ['Animals', 'Diabetes Mellitus, Type 2', 'Enzyme Inhibitors', 'Glycoside Hydrolase Inhibitors', 'Lipid Peroxidation', 'Nitroprusside', 'Pancreas', 'Plant Components, Aerial', 'Plant Extracts', 'Rats', 'Rats, Wistar', 'Spices', 'alpha-Amylases'] | 22,480,175 | [['B01.050'], ['C18.452.394.750.149', 'C19.246.300'], ['D27.505.519.389'], ['D27.505.519.389.320', 'D27.505.696.422.249'], ['G02.111.515', 'G03.295.531.587'], ['D01.248.497.158.291.350.550', 'D01.490.100.300.550', 'D01.625.400.100.325.550'], ['A03.734'], ['A18.024'], ['D20.215.784.500', 'D26.667'], ['B01.050.150.900.64... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ontogenetic allometry of the Beagle. | BACKGROUND: Mammalian juveniles undergo dramatic changes in body conformation during development. As one of the most common companion animals, the time line and trajectory of a dog's development and its body's re-proportioning is of particular scientific interest. Several ontogenetic studies have investigated the skele... | ['Animals', 'Biomechanical Phenomena', 'Dogs', 'Male', 'Species Specificity'] | 24,112,520 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.750.250.216.200'], ['G16.824']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Sauna effect on blood oxygen transport function and proxidant/antioxidant balance in youths]. | There was investigated sauna effect on blood oxygen transport function and proxidant/antioxidant balance in 18 to 22 years old males. Subjects being tested underwent thermal exposure once per week over a period of 5 months (20 procedures). There were two exposure over the course of sauna bathing (temperature 85-90 degr... | ['Adolescent', 'Adult', 'Antioxidants', 'Biological Transport', 'Hot Temperature', 'Humans', 'Male', 'Oxidants', 'Oxygen', 'Steam Bath', 'Time Factors'] | 23,101,249 | [['M01.060.057'], ['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G03.143'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.642', 'D27.88... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Infection burden and immunological responses are equivalent for polymeric and metallic implant materials in vitro and in a murine model of fracture-related infection. | The development of an infection is a major complication for some patients with implanted biomaterials. Whether the material or surface composition of the used biomaterial influences infection has not been directly compared for key biomaterials currently in use in human patients. We conducted a thorough in vitro and in ... | ['Animals', 'Bone Diseases, Infectious', 'Disease Models, Animal', 'Female', 'Humans', 'Implants, Experimental', 'Ketones', 'Materials Testing', 'Mice', 'Mice, Inbred BALB C', 'Osseointegration', 'Polyethylene Glycols', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 30,332,531 | [['B01.050'], ['C01.160', 'C05.116.165'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.340'], ['D02.522'], ['E05.570'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['G11.427.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Treatment of Benign Prostatic Hyperplasia by Longbishu Capsule Combined Doxazosin Mesylate Tablet]. | Objective To observe the efficacy and safety of Longbishu Capsule (LBS) com- bined Doxazosin Mesylate Tablet (DMT) in treating benign prostatic hyperplasia (BPH). Methods Total- ly 360 BPH with Shen deficiency blood stasis syndrome (SDBSS) were randomly assigned to group A, B, and C, 120 cases in each group. Patients i... | ['Aged', 'Capsules', 'Doxazosin', 'Drugs, Chinese Herbal', 'Humans', 'Male', 'Prostatic Hyperplasia', 'Quality of Life', 'Treatment Outcome'] | 30,650,291 | [['M01.060.116.100'], ['D26.255.150'], ['D03.633.100.786.750.200'], ['D20.215.784.500.350', 'D26.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.565.500'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Circulating serum level of retinoic acid and hip fractures among postmenopausal women. | PURPOSE: The aim of this study was to evaluate the serum levels of retinoic acid (RA), an active form of vitamin A, in postmenopausal women with hip fractures from Zhengzhou, China.METHODS: This was a case-control study from the Affiliated Hospital of Zhengzhou University. Serum samples were drawn from 375 postmenopaus... | ['Aged', 'Case-Control Studies', 'Female', 'Hip Fractures', 'Humans', 'Middle Aged', 'Postmenopause', 'Risk Factors', 'Tretinoin'] | 30,517,774 | [['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.157.500.625', 'G08.686.841.249.500.625'], ['E05.318.740.600.800.725', 'N05.715.350.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of the acute biological action of injectable salmon calcitonin and an injectable and oral calcitonin analogue. | In most countries, calcitonin is available in the form of injections, and less frequently as an intranasal spray. An oral route of administration should improve compliance. In a preliminary feasibility study, we have compared the acute biological action of injectable salmon calcitonin (50 IU), with the injectable calci... | ['Administration, Intranasal', 'Administration, Oral', 'Aged', 'Bone Resorption', 'Calcitonin', 'Chromatography, High Pressure Liquid', 'Feasibility Studies', 'Female', 'Humans', 'Injections, Subcutaneous', 'Male', 'Middle Aged', 'Osteitis Deformans'] | 7,922,793 | [['E02.319.267.120.655.500'], ['E02.319.267.100'], ['M01.060.116.100'], ['C05.116.264', 'G11.427.213.150'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['E05.196.181.400.300'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Active safety monitoring of newly marketed medications in a distributed data network: application of a semi-automated monitoring system. | We developed a semi-automated active monitoring system that uses sequential matched-cohort analyses to assess drug safety across a distributed network of longitudinal electronic health-care data. In a retrospective analysis, we show that the system would have identified cerivastatin-induced rhabdomyolysis. In this stud... | ['Aged', 'Anti-Bacterial Agents', 'Azithromycin', 'Chemical and Drug Induced Liver Injury', 'Diabetes Mellitus', 'Drug Monitoring', 'Electronic Data Processing', 'Electronic Health Records', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Ketolides', 'Male', 'Outcome Assessment, Health Care', 'Pr... | 22,588,606 | [['M01.060.116.100'], ['D27.505.954.122.085'], ['D02.540.576.500.992.050'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['C18.452.394.750', 'C19.246'], ['E01.370.520.200'], ['L01.224.085'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Care of the HIV-exposed child--to breast feed or not? | Breast milk is the best form of nutrition for infants. However, it places infants born to HIV infected women at risk of acquiring HIV infection. Total avoidance of breastfeeding is the only way of completely avoiding HIV transmission through breast milk. However, this strategy has not proved to be viable in resource co... | ['Anti-HIV Agents', 'Breast Feeding', 'Female', 'HIV Infections', 'HIV-1', 'Humans', 'India', 'Infant', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Milk, Human', 'Practice Guidelines as Topic', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Risk Factors'] | 22,382,511 | [['D27.505.954.122.388.077.088'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.4... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Specific expression of miR-17-5p and miR-127 in testicular and central nervous system diffuse large B-cell lymphoma. | Recent studies have shown that certain non-coding short RNAs, called miRNAs, play an important role in diffuse large B-cell lymphomas. Patients with diffuse large B-cell lymphoma have great diversity in both clinical characteristics, site of presentation and outcome. The aim of our study is to validate the differential... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Central Nervous System Neoplasms', 'Female', 'Germinal Center', 'Humans', 'In Situ Hybridization', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'MicroRNAs', 'Middle Aged', 'Reverse Transcriptase Polymerase Chain Reaction', 'Testicular Neoplasms', 'Tissue Array Analysi... | 19,287,466 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.614.250', 'C10.551.240'], ['A10.549.400.500', 'A15.382.520.604.412.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuroticism, major depression and gender: a population-based twin study. | BACKGROUND: A portion of the genetic risk factors for the personality trait neuroticism (N) may also increase risk for major depression (MD). Females have both higher levels of N and higher rates of MD than males, suggesting that these traits may be more genetically correlated in females.METHODS: Structured interviews,... | ['Adult', 'Aged', 'Comorbidity', 'Cross-Sectional Studies', 'Depressive Disorder, Major', 'Diseases in Twins', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Middle Aged', 'Models, Genetic', 'Neurotic Disorders', 'Personality Inventory', 'Psychometrics', 'Risk Factors', 'Sex Factors', 'Twins, Dizygot... | 12,102,386 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.600.300.375'], ['C23.550.291.750'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Interaction of Avibactam with Class B Metallo-â-Lactamases. | â-Lactamases are the most important mechanisms of resistance to the â-lactam antibacterials. There are two mechanistic classes of â-lactamases: the serine â-lactamases (SBLs) and the zinc-dependent metallo-â-lactamases (MBLs). Avibactam, the first clinically useful non-â-lactam â-lactamase inhibitor, is a broad-spectru... | ['Azabicyclo Compounds', 'Ceftazidime', 'Hydrolysis', 'Magnetic Resonance Spectroscopy', 'Spectrophotometry, Ultraviolet', 'beta-Lactamase Inhibitors', 'beta-Lactamases'] | 27,401,561 | [['D02.145.074', 'D03.605.084.500'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['G02.380'], ['E05.196.867.519'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D27.505.519.389.400', 'D27.505.954.122.085.516'], ['D08.811.277.087.180']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal vascular and tubular effects of vanadate in the anesthetized rat. | The purpose of these experiments was to establish the renal vascular and tubular effects of vanadate. Three groups of adult rats were anesthetized with Na pentobarbital and given an i.v. infusion of a physiological saline solution at 0.055 ml/min. After a 60-min equilibration period, mean arterial blood pressure was me... | ['Animals', 'Blood Pressure', 'Calcium', 'Diuresis', 'Glomerular Filtration Rate', 'Kidney', 'Kidney Tubules', 'Male', 'Potassium', 'Rats', 'Sodium', 'Vanadates', 'Vanadium'] | 6,908,914 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G08.852.179'], ['E01.370.390.400.300', 'G08.852.357'], ['A05.810.453'], ['A05.810.453.736.560'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Diversified treatments of Tinea unguium]. | Antifungal agents and therapeutic approaches for tinea unguium have been increasing in number. Itraconazole, terbinafine and fluconazole were developed in the 1990s, and many useful methods with them for tinea unguium have been reported, including pulse therapy and short duration therapy. There have been many reports o... | ['Administration, Oral', 'Antifungal Agents', 'Combined Modality Therapy', 'Fluconazole', 'Griseofulvin', 'Humans', 'Itraconazole', 'Naphthalenes', 'Occlusive Dressings', 'Onychomycosis', 'Pulse Therapy, Drug', 'Terbinafine'] | 12,040,365 | [['E02.319.267.100'], ['D27.505.954.122.136'], ['E02.186'], ['D03.383.129.799.450'], ['D03.633.100.127.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.799.550', 'D03.383.606.530'], ['D02.455.426.559.847.638', 'D04.615.638'], ['E07.101.650'], ['C01.150.703.302.720.550', 'C01.800.200.720.550', 'C17.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crystal structure of a zinc-finger-RNA complex reveals two modes of molecular recognition. | Zinc-finger proteins of the classical Cys2His2 type are the most frequently used class of transcription factor and account for about 3% of genes in the human genome. The zinc-finger motif was discovered during biochemical studies on the transcription factor TFIIIA, which regulates the 5S ribosomal RNA genes of Xenopus ... | ['Amino Acid Sequence', 'Base Sequence', 'Binding Sites', 'Crystallography, X-Ray', 'Models, Molecular', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Protein Conformation', 'RNA, Ribosomal, 5S', 'Substrate Specificity', 'Transcription Factor TFIIIA', 'Zinc Fingers'] | 14,603,324 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['E05.599.595'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['G02.111.570.820.709'], ['D13.444.735.686.650'], ['G02.111.835'], ['D12.776.260.775.937.249... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Management System of Implantable Medical Device in Accordance with JCI Standard Based on HRP System]. | JCI standard is the most professional and authoritative certification standard of medical quality and safety system in the world. HRP information system is a systematic hospital resource management platform which integrates the existing hospital information resources and establishes a set of unified, efficient, interco... | ['Hospitals', 'Humans', 'Information Dissemination', 'Management Information Systems', 'Prostheses and Implants'] | 31,460,730 | [['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['N04.452.515'], ['E07.695']] | ['Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Objective assessment of psoriasis erythema for PASI scoring. | Skin colour is vital information in dermatological diagnosis. It reflects pathological condition beneath the skin and commonly being used to indicate the extent of a disease. Psoriasis is a skin disease which is indicated by the appearance of red plaques. Although there is no cure for psoriasis, there are many treatmen... | ['Algorithms', 'Dermatology', 'Diagnosis, Computer-Assisted', 'Equipment Design', 'Humans', 'Models, Statistical', 'Models, Theoretical', 'Observer Variation', 'Pattern Recognition, Automated', 'Psoriasis', 'Skin', 'Skin Pigmentation', 'Vision, Ocular'] | 19,163,606 | [['G17.035', 'L01.224.050'], ['H02.403.225'], ['E01.158', 'L01.313.500.750.100.158'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.599'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.25... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Recombinant advanced glycation end product receptor pharmacokinetics in normal and diabetic rats. | Vascular dysfunction in patients with diabetes mellitus is related to advanced glycation end product (AGE) formation. We previously showed that AGEs produce an increase in vascular permeability and generated an oxidant stress after binding to the receptor (RAGE) present on endothelium. RAGE, a 35-kDa protein that belon... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Capillary Permeability', 'Cattle', 'Cloning, Molecular', 'Diabetes Mellitus, Experimental', 'Humans', 'Molecular Sequence Data', 'Rats', 'Receptor for Advanced Glycation End Products', 'Receptors, Immunologic', 'Recombinant Proteins', 'Streptozocin', 'Tissue Distribu... | 9,224,812 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G03.143.330', 'G09.330.165'], ['B01.050.150.900.649.313.500.380.271'], ['E05.393.220'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
M?ller glia provide essential tensile strength to the developing retina. | To investigate the cellular basis of tissue integrity in a vertebrate central nervous system (CNS) tissue, we eliminated M?ller glial cells (MG) from the zebrafish retina. For well over a century, glial cells have been ascribed a mechanical role in the support of neural tissues, yet this idea has not been specifically ... | ['Animals', 'Ependymoglial Cells', 'Microscopy, Atomic Force', 'Retina', 'Tensile Strength', 'Zebrafish'] | 26,416,961 | [['B01.050'], ['A08.637.300', 'A11.650.300'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['A09.371.729'], ['G01.374.850'], ['B01.050.150.900.493.200.244.828']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Climate and competition: the effect of moving range boundaries on habitat invasibility. | Predictions for climate change include movement of temperature isoclines up to 1000 m/year, and this is supported by recent empirical studies. This paper considers effects of a rapidly changing environment on competitive outcomes between species. The model is formulated as a system of nonlinear partial differential equ... | ['Animals', 'Competitive Behavior', 'Environment', 'Greenhouse Effect', 'Models, Biological', 'Numerical Analysis, Computer-Assisted'] | 15,294,415 | [['B01.050'], ['F01.145.813.105'], ['G16.500.275', 'N06.230'], ['G16.500.175.827', 'N06.230.265'], ['E05.599.395'], ['L01.224.680.700']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes. | The mouse Vanin-1 molecule plays a role in thymic reconstitution following damage by irradiation. We recently demonstrated that it is a membrane pantetheinase (EC 3.56.1.-). This molecule is the prototypic member of a larger Vanin family encoded by at least two mouse (Vanin-1 and Vanin-3) and three human (VNN1, VNN2, V... | ['Amidohydrolases', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Adhesion Molecules', 'Chromosomes, Human, Pair 6', 'Conserved Sequence', 'GPI-Linked Proteins', 'Humans', 'Membrane Proteins', 'Mice', 'Molecular Sequence Data', 'Multigene Family', 'Protein Isoforms', 'Sequence Homology, Amino Acid', 'Tissue ... | 11,491,533 | [['D08.811.277.087'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['A11.284.187.520.300.325.330', 'G05.360.162.520.300.325.330'], ['G02.111.570.580'], ['D12.776.395.550.448', 'D12.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phase-field simulations at the atomic scale in comparison to molecular dynamics. | Early solidification is investigated using two different simulation techniques: the molecular dynamics (MD) and the phase-field (PF) methods. While the first describes the evolution of a system on the basis of motion equations of particles, the second grounds on the evolution of continuous local order parameter field. ... | ['Molecular Dynamics Simulation'] | 24,453,874 | [['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Limited Sampling Strategy for the Estimation of Tacrolimus Area Under the Concentration-Time Curve in Chinese Adult Liver Transplant Patients. | OBJECTIVES: Limited sampling strategies (LSS) have been proposed as an alternative method for estimating area under concentration-time curve (AUC) of immunosuppressive agent tacrolimus (TAC). In this study, we aimed to develop the LSS models for predicting AUC of TAC in Chinese liver transplant patients.METHODS: Twenty... | ['Adult', 'Area Under Curve', 'Asian Continental Ancestry Group', 'Female', 'Graft Rejection', 'Humans', 'Immunosuppressive Agents', 'Liver Transplantation', 'Male', 'Middle Aged', 'Tacrolimus', 'Time Factors'] | 27,449,772 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['M01.686.508.200'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['D02.540... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evidence for positive Darwinian selection of Vip gene in Bacillus thuringiensis. | Vegetative insecticidal proteins (VIPs), produced during the vegetative stage of their growth in Bacillus thuringiensis, are a group of insecticidal proteins and represent the second generation of insecticidal trans-genes that will complement the novel delta-endotoxins in future. Fewer structural and functional relatio... | ['Amino Acid Sequence', 'Bacillus thuringiensis', 'Bacterial Proteins', 'Chromosome Mapping', 'Evolution, Molecular', 'Likelihood Functions', 'Molecular Sequence Data', 'Phylogeny', 'Selection, Genetic', 'Sequence Alignment'] | 17,643,951 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['D12.776.097'], ['E05.393.183'], ['G05.045.250', 'G16.075.250'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Sudden death in leukemic patients treated with doxorubicin]. | Cardiotoxicity of the anthracycline antineoplastic drugs is well known, especially the chronic effects, manifested mainly as congestive heart failure. Fewer reports have been published about the acute cardiotoxicity of these medications, and risk factors associated with their use. Two cases of malignant arrhythmias lea... | ['Daunorubicin', 'Death, Sudden, Cardiac', 'Heart Failure', 'Humans', 'Leukemia, Myeloid, Acute', 'Leukemia, Myelomonocytic, Acute', 'Middle Aged', 'Risk Factors'] | 1,617,512 | [['D02.455.426.559.847.562.050.200', 'D04.615.562.050.200', 'D09.408.051.059.200'], ['C14.280.383.220', 'C23.550.260.322.250'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['C04.557.337.539.520'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[On "2015 Guidelines for Prevention and Treatment of Osteoporosis". CKD and osteoporosis]. | Many patients with osteoporosis have complicated with CKD. It was reported that the risk of hip and vertebral fracture is higher in osteoporosis patients with CKD than without CKD. Because the drugs for osteoporosis are excreted by kidney, there are no drugs that the efficacy and safety were established for the CKD pat... | ['Humans', 'Osteoporosis', 'Osteoporotic Fractures', 'Practice Guidelines as Topic', 'Renal Insufficiency, Chronic', 'Risk Factors', 'Vitamin D Deficiency'] | 26,320,533 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.198.579', 'C18.452.104.579'], ['C26.404.545'], ['N04.761.700.350.650', 'N05.700.350.650'], ['C12.777.419.780.750', 'C13.351.968.419.780.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
âIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells. | Non-small cell lung cancer (NSCLC) survival rates are dismal and high âIII-tubulin expression is associated with chemotherapy drug resistance and tumor aggressiveness in this disease. Mounting evidence supports a role for âIII-tubulin in promoting cell survival in the harsh tumor microenvironment, which is characterize... | ['Autophagy', 'Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Drug Resistance, Neoplasm', 'Endoplasmic Reticulum Stress', 'Glucose', 'Heat-Shock Proteins', 'Humans', 'Oncogene Protein v-akt', 'Signal Transduction', 'Tubulin', 'Tumor Microenvironment'] | 27,207,668 | [['G04.011'], ['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G07.690.773.984.395'], ['G04.434'], ['D09.947.875.359.448'], ['D12.776.580.216'], ['B01.050.150.900.649.313... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-interleukin-1â antibody prevents the occurrence of repeated restraint stress-induced alterations in synaptic transmission and long-term potentiation in the rat frontal cortex. | BACKGROUND: The mechanisms of the influence of prolonged stress on glutamatergic transmission and synaptic plasticity in the cerebral cortex remain poorly understood. The purpose of this study was to determine an involvement of interleukin-1â (IL-1â) in the effects of repeated restraint stress on excitatory synaptic tr... | ['Adrenocorticotropic Hormone', 'Animals', 'Antibodies, Blocking', 'Corticosterone', 'Evoked Potentials', 'Hormones', 'In Vitro Techniques', 'Interleukin-1beta', 'Long-Term Potentiation', 'Male', 'Prefrontal Cortex', 'Rats', 'Rats, Wistar', 'Restraint, Physical', 'Stress, Psychological', 'Synaptic Transmission'] | 25,560,585 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['D12.776.124.486.485.114.143', 'D12.776.124.790.651.114.143', 'D12.776.377.715.548.114.143'], ['D04.210.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[An experimental study on the protective effect of nizofenone in cerebral ischemia]. | Using the "canine model of complete ischemic brain regulated with a perfusion method" in which it is possible to control the degree of blood flow to a cerebral hemisphere via a perfusion pump, the protective effects of nizofenone against cerebral ischemia was investigated. After pre-treatment with nizofenone, blood flo... | ['Animals', 'Brain Ischemia', 'Cerebrovascular Circulation', 'Dogs', 'Dose-Response Relationship, Drug', 'Electroencephalography', 'Humans', 'Imidazoles', 'Perfusion'] | 6,525,322 | [['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G09.330.100.159'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['E05.680']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
B4GALT1 gene knockdown inhibits the hedgehog pathway and reverses multidrug resistance in the human leukemia K562/adriamycin-resistant cell line. | B4GALT1 gene encodes type II membrane-bound glycoprotein, named â-1, 4-galactosyltransferase 1 (â1, 4-Gal-T1), which can transfer galactose to acceptor sugars. B4GALT1 gene plays important roles in physiological process and disease development. In this study, we investigate the possible role and mechanism of B4GALT1 ge... | ['Animals', 'Antibiotics, Antineoplastic', 'Blotting, Western', 'Doxorubicin', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Flow Cytometry', 'Galactosyltransferases', 'Gene Expression Regulation, Neoplastic', 'Hedgehog Proteins', 'Humans', 'Immunoenzyme Techniques', 'Leukemia, Experimental', 'Male', 'Mice... | 23,024,026 | [['B01.050'], ['D27.505.954.248.106'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['G07.690.773.984.300'], ['G07.690.773.984.395'], ['E01.370.225.500.363.342', 'E01.37... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Direction of change in the somatic development in children and adolescents with type 1 diabetes]. | INTRODUCTION: Disorders of somatic development in children and adolescents with type 1 diabetes can lead to unstable course of the disease and the difficulties in obtaining good metabolic control.AIM: Evaluation of somatic development in children and adolescents with type 1 diabetes in different age categories.MATERIAL... | ['Adolescent', 'Adolescent Development', 'Age Factors', 'Anthropometry', 'Child', 'Child Development', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Male', 'Poland', 'Sex Factors'] | 29,073,291 | [['M01.060.057'], ['F01.525.049', 'G07.345.374.500'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The interactions of a selective protein kinase C beta inhibitor with the human cytochromes P450. | Studies were performed to determine the cytochromes P450 (P450) responsible for the biotransformation of (S)-13[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione (LY333531) to its equipotent metabolite, N-desmethyl LY333531,... | ['Aryl Hydrocarbon Hydroxylases', 'Cytochrome P-450 CYP1A2', 'Cytochrome P-450 CYP2C9', 'Cytochrome P-450 CYP2D6', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 Enzyme System', 'Enzyme Inhibitors', 'Humans', 'In Vitro Techniques', 'Indoles', 'Isoenzymes', 'Maleimides', 'Microsomes, Liver', 'Oxidoreductases, N-Demethylati... | 12,167,559 | [['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['D08.244.453.005.443', 'D08.244.453.100.750', 'D08.811.682.690.708.170.010.443', 'D08.811.682.690.708.170.020.750', 'D12.776.422.220.453.010.443', 'D12.776.422.220.453.100.750'], ['D08.244.453.491.500.500', 'D08.811.682.690.708.170.450.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel echocardiographic hemodynamic index for predicting outcome of aortic stenosis patients following transcatheter aortic valve replacement. | OBJECTIVE: Transcatheter aortic valve replacement (TAVR) reduces left ventricular (LV) afterload and improves prognosis in aortic stenosis (AS) patients. However, LV afterload consists of both valvular and arterial loads, and the benefits of TAVR may be attenuated if the arterial load dominates. We proposed a new hemod... | ['Aged, 80 and over', 'Aortic Valve', 'Aortic Valve Stenosis', 'Echocardiography', 'Female', 'Follow-Up Studies', 'Hemodynamics', 'Humans', 'Male', 'Multivariate Analysis', 'Prognosis', 'Proportional Hazards Models', 'Sensitivity and Specificity', 'Severity of Illness Index', 'Transcatheter Aortic Valve Replacement', '... | 29,698,407 | [['M01.060.116.100.080'], ['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ileal schwannoma causing intussusception in an adult. | Ileal schwannomas are extremely rare tumours. Very few cases have been previously reported. Most cases present with abdominal pain and gastrointestinal bleeding; intussusception is a rare presentation. Due to limitations in imaging modalities, arriving at a diagnosis preoperatively can be challenging. The only reliable... | ['Abdominal Pain', 'Adult', 'Anastomosis, Surgical', 'Female', 'Humans', 'Ileal Neoplasms', 'Ileum', 'Intestine, Small', 'Intussusception', 'Laparotomy', 'Neurilemmoma', 'Rare Diseases', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 30,381,306 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.116'], ['E04.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411.501', 'C06.301.371.411.501', 'C06.405.249.411.501', 'C06.405.469.420.501', 'C06.405.469.491.501'], ['A03.556.124.684.249', 'A03.556.249.124'], ['A03.556.124.684'], ['C06.405.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Levetiracetam may favorably affect seizure outcome after temporal lobectomy. | PURPOSE: To study the prognostic implications of antiepileptic drug (AED) use on seizure freedom following temporal lobe resections for intractable epilepsy.METHODS: Seizure outcome implications of epilepsy characteristics and AED use were studied in patients who underwent temporal lobectomy patients at the Cleveland C... | ['Adolescent', 'Adult', 'Aged', 'Anterior Temporal Lobectomy', 'Anticonvulsants', 'Child', 'Child, Preschool', 'Epilepsy', 'Female', 'Humans', 'Levetiracetam', 'Longitudinal Studies', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Piracetam', 'Positron-Emission Tomography', 'Postoperative Complications', 'Recurr... | 22,462,729 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.043', 'E04.525.044'], ['D27.505.954.427.080'], ['M01.060.406'], ['M01.060.406.448'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.064.432', 'D02.241.081.018.110.463', 'D03.383.773.812.362'], ['E05.318.372.500.750.500', 'N05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Higher density of mental capacities in the left cerebral hemisphere of man: a quantitative investigation in children with localized cerebral lesions. | 51 children with localized cerebral lesions were investigated with the British Ability Scales, Wechsler test, Porteus Mazes, Conners Teacher Rating Scale, and computerized tomography. The extent of the lesions was quantitatively determined. The IQ was 10 points lower in the left hemispheric lesions, although the right ... | ['Adolescent', 'Aptitude', 'Aptitude Tests', 'Brain Damage, Chronic', 'Child', 'Child Behavior Disorders', 'Child, Preschool', 'Dominance, Cerebral', 'Epilepsy', 'Hemiplegia', 'Humans', 'Intelligence', 'Mental Processes', 'Wechsler Scales'] | 3,753,140 | [['M01.060.057'], ['F02.784.629.131'], ['F04.711.141'], ['C10.228.140.140'], ['M01.060.406'], ['F03.625.141'], ['M01.060.406.448'], ['F02.830.297', 'G11.561.225'], ['C10.228.140.490'], ['C10.597.622.295', 'C23.888.592.636.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['F02.463'], ['F04.711.14... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human CD4+ CD25 high cells suppress proliferative memory lymphocyte responses to herpes simplex virus type 2. | Lymphocytes with the regulatory CD4+ CD25+ phenotype frequently suppress memory T-cell responses. Murine herpes simplex virus type 1 (HSV-1) models have shown that CD4+ CD25+ cells can limit immunity-mediated corneal damage but slow viral clearance. We investigated the effect of CD4+ CD25+ cells from healthy HSV-2-infe... | ['Animals', 'Antigens, Viral', 'CD4-Positive T-Lymphocytes', 'Herpesvirus 2, Human', 'Humans', 'Immunologic Memory', 'Lymphocyte Activation', 'Mice', 'Receptors, Interleukin-2', 'T-Lymphocytes, Regulatory'] | 16,873,284 | [['B01.050'], ['D23.050.327'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['B04.280.382.100.750.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.500'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of soft tissue morphologic changes after using the alar base cinch suture in Le Fort I osteotomy in mandibular prognathism with and without asymmetry. | PURPOSE: The purpose of this study was to investigate the effects of alar base cinch suture in Le Fort I osteotomy in mandibular prognathism with and without asymmetry.MATERIAL AND METHODS: Forty patients who underwent Le Fort I osteotomy were divided into an asymmetry group and a symmetry group (n = 20 each). Computed... | ['Adolescent', 'Adult', 'Cephalometry', 'Face', 'Facial Asymmetry', 'Female', 'Follow-Up Studies', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Lip', 'Male', 'Mandible', 'Middle Aged', 'Nasal Cartilages', 'Open Bite', 'Osteotomy, Le Fort', 'Osteotomy, Sagittal Split Ramus', 'Prognathi... | 24,424,271 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['A01.456.505'], ['C23.300.505'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.22... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Safe mobility, socioeconomic inequalities, and aging: A 12-year multilevel interrupted time-series analysis of road traffic death rates in a Latin American country. | As the resources for road safety in developing countries are scarce and unevenly distributed, vulnerable road users -such as the elderly- may be particularly at risk of road traffic deaths. To date, the impact of road safety measures over the rate of road traffic deaths in older adults (60 years or older), considering ... | ['Accidents, Traffic', 'Aged', 'Aged, 80 and over', 'Aging', 'Chile', 'Humans', 'Middle Aged', 'Social Class'] | 31,910,212 | [['N06.850.135.392'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['Z01.107.757.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.880.853.996.755', 'N01.824.782']] | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Novel and emerging drugs for rarer chronic lymphoid leukaemias. | Rarer chronic lymphoid leukaemias represent a challenge to the clinicians due to the limited information on their pathogenesis, difficulties on setting up prospective clinical trials and to their refractoriness to drugs used in the most common form of chronic lymphocytic leukaemia (CLL). In this review all these issues... | ['Animals', 'Antineoplastic Agents', 'Clinical Trials, Phase I as Topic', 'Clinical Trials, Phase II as Topic', 'Drug Evaluation, Preclinical', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Prospective Studies', 'Rare Diseases'] | 22,483,155 | [['B01.050'], ['D27.505.954.248'], ['E05.318.372.250.250.200', 'N05.715.360.330.250.250.200', 'N06.850.520.450.250.250.200'], ['E05.318.372.250.250.210', 'N05.715.360.330.250.250.210', 'N06.850.520.450.250.250.210'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.080.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of pulmonary impairment on all-cause mortality in a national cohort. | The association between pulmonary impairment and all-cause mortality was investigated among white subjects in a follow-up study of a large national cohort. Pulmonary function was measured during the National Health and Nutrition Examination Survey (NHANESI) (1971 to 1975); subsequent mortality information was obtained ... | ['Adult', 'Aged', 'Cohort Studies', 'Female', 'Forced Expiratory Volume', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Risk Factors', 'Sex Factors', 'Smoking', 'United States', 'Vital Capacity'] | 8,432,150 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Measuring the capacity of families to provide unpaid support for a disabled family member: using BIGSTEPS to identify primary and secondary dimensions. | The Principal Components subroutine of the BIGSTEPS computer program (Rasch analysis) was used to identify primary and secondary dimensions within an item set composed of variables pertaining to family capacity to provide assistance to a family member with disability. Data were obtained through interviews with family c... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Aged', 'Attitude to Health', 'Cost of Illness', 'Disabled Persons', 'Factor Analysis, Statistical', 'Family', 'Female', 'Home Nursing', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Needs Assessment', 'Numerical Analysis, Computer-Assisted', 'Patient Di... | 11,272,595 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['M01.150'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.52... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells. | Telomeres are essential for protecting the ends of chromosomes and preventing chromosome fusion. Telomere loss has been proposed to play an important role in the chromosomal rearrangements associated with tumorigenesis. To determine the relationship between telomere loss and chromosome instability in mammalian cells, w... | ['Animals', 'Cloning, Molecular', 'DNA', 'DNA Damage', 'Deoxyribonucleases, Type II Site-Specific', 'Embryo, Mammalian', 'Female', 'Gene Rearrangement', 'Genetic Markers', 'Humans', 'Male', 'Mice', 'Mice, Inbred Strains', 'Molecular Sequence Data', 'Plasmids', 'Repetitive Sequences, Nucleic Acid', 'Saccharomyces cerevi... | 12,052,890 | [['B01.050'], ['E05.393.220'], ['D13.444.308'], ['G05.200'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['A16.254'], ['G05.344'], ['D23.101.387', 'G05.695.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.05... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Veterans and suicide: a reexamination of the National Death Index-linked National Health Interview Survey. | OBJECTIVES: We assessed the risk of suicide among veterans compared with nonveterans.METHODS: Cox proportional hazards models estimated the relative risk of suicide, by self-reported veteran status, among 500,822 adult male participants in the National Death Index (NDI)-linked National Health Interview Survey (NHIS), a... | ['Adolescent', 'Adult', 'Aged', 'Cause of Death', 'Humans', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Registries', 'Risk Assessment', 'Risk Factors', 'Suicide', 'United States', 'Veterans'] | 22,390,591 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Creative teaching assistant organization to maintain an Integrative Physiology course with 440 students. | We were recently challenged with trying to maintain the integrity and learning experience of our Physiology course, which included the use of long-answer, essay-style test questions, with a class size that increased over 2 yr by approximately 200 students. We reorganized the teaching assistant (TA) support structure in... | ['Adolescent', 'Adult', 'Educational Measurement', 'Faculty', 'Humans', 'Interpersonal Relations', 'Learning', 'Ontario', 'Physiology', 'Students', 'Teaching'] | 17,562,908 | [['M01.060.057'], ['M01.060.116'], ['I02.399'], ['M01.526.702.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.425', 'F02.784.629.529'], ['Z01.107.567.176.639'], ['H01.158.782'], ['M01.848'], ['I02.903']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 |
Total cost comparison in relapsed/refractory multiple myeloma. | OBJECTIVES: Advances in survival in multiple myeloma have focused payer attention on the cost of care. An assessment was conducted to compare the costs of two recent treatments for relapsed/refractory multiple myeloma (rrMM), from the perspective of a US payer.METHODS: An economic model estimated the total costs of car... | ['Antineoplastic Agents', 'Boronic Acids', 'Bortezomib', 'Dexamethasone', 'Fees, Pharmaceutical', 'Health Expenditures', 'Humans', 'Lenalidomide', 'Models, Economic', 'Multiple Myeloma', 'Neoplasm Recurrence, Local', 'Pyrazines', 'Thalidomide'] | 23,281,721 | [['D27.505.954.248'], ['D01.029.260.110', 'D01.132.285', 'D02.203.200'], ['D01.029.260.110.500', 'D01.132.285.500', 'D02.203.200.500', 'D03.383.679.450'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['N03.219.442.551'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Development of multiple warts after skin resurfacing with CO2 laser. | BACKGROUND: Skin resurfacing with CO2 laser is a common surgical procedure to improve photodamaged skin. Many complications may occur after this procedure, however, common warts is relatively rare.OBJECTIVE: To report a case of multiple warts after CO2 laser resurfacing and discuss the complete involution of these lesi... | ['Aged', 'Facial Dermatoses', 'Female', 'Humans', 'Laser Therapy', 'Rhytidoplasty', 'Skin Aging', 'Warts'] | 10,632,690 | [['M01.060.116.100'], ['C17.800.271'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['E02.218.765', 'E04.680.275.700'], ['G13.750.804'], ['C01.925.256.650.810', 'C01.925.825.810', 'C01.925.928.914', 'C17.800.838.790.810']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A preliminary study of long-term epidural morphine for cancer pain via a subcutaneously implanted reservoir. | A series of 252 patients with terminal cancer (mostly with bony metastases) were treated with epidural morphine. Results were good to excellent pain relief in 85% of patients, but those with malignant growths above the neck showed relatively poor response. For those who survived more than 3 months, the daily morphine r... | ['Adult', 'Aged', 'Analgesia, Epidural', 'Female', 'Humans', 'Infusion Pumps', 'Male', 'Middle Aged', 'Morphine', 'Neoplasms', 'Pain', 'Self Administration', 'Time Factors'] | 2,725,185 | [['M01.060.116'], ['M01.060.116.100'], ['E03.091.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.505', 'E07.858.082.505'], ['M01.060.116.630'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['C04'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A collaborative European study of personal inhalable aerosol sampler performance. | Following the adoption of new international sampling conventions for inhalable, thoracic and respirable aerosol fractions, a working group of Comit? Europ?en de Normalisation (CEN) drafted a standard for the performance of workplace aerosol sampling instruments. The present study was set up to verify the experimental, ... | ['Europe', 'Humans', 'Nebulizers and Vaporizers', 'Particle Size'] | 9,155,236 | [['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.605'], ['G02.712']] | ['Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Brain serotonergic activity and plasma amino acid levels in genetically obese Zucker rats. | In order to test the hypothesis that serotonergic activity is abnormal in the brains of genetically obese Zucker rats, levels of serotonin (5-HT); its amino acid precursor, tryptophan (Trp), and its major metabolite, 5-hydroxyindoleacetic acid (5-HIAA) were measured in eight brain regions in groups of obese and non-obe... | ['Amino Acids', 'Animals', 'Body Weight', 'Brain', 'Eating', 'Hydroxyindoleacetic Acid', 'Male', 'Rats', 'Rats, Zucker', 'Serotonin', 'Serum Albumin', 'Tryptophan'] | 6,184,736 | [['D12.125'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['G07.203.650.283', 'G10.261.330'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Personal view: randomized controlled trials in epilepsy specialist nursing: the seduction of content by form. | Research into the effectiveness of epilepsy specialist nursing needs to take into account a number of factors, which have not been adequately addressed in previous studies. Nursing outcome measures are different to medical ones and it is inappropriate to confuse these. Specialist nurses affect the whole culture of a se... | ['Humans', 'Nurse Clinicians', 'Nursing Services', 'Randomized Controlled Trials as Topic'] | 12,185,774 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.650.648.525', 'N02.360.650.648.525'], ['N02.421.539'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500']] | ['Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of extraocular muscles in the edematous phase of Graves ophthalmopathy on contrast-enhanced fat-suppressed magnetic resonance imaging. | OBJECTIVE: Extraocular muscles (EOMs) reveal characteristic contrast-enhancement patterns on magnetic resonance (MR) imaging due to their rich vascular supply. The objective of this study was to evaluate contrast-enhancement patterns of EOMs in patients with edematous phase of Graves ophthalmopathy (GO) using contrast-... | ['Acute Disease', 'Adult', 'Contrast Media', 'Edema', 'Female', 'Gadolinium DTPA', 'Graves Disease', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Oculomotor Muscles', 'Orbital Diseases'] | 14,716,237 | [['C23.550.291.125'], ['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['C23.888.277'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Higher glucose level and systemic oxidative stress decrease the mean velocity index of the retinal artery during flickering light stimulation in type 1 diabetes. | AIM: To determine whether higher glucose level and systemic oxidative stress decrease mean velocity (MV) index of the central retinal artery (CRA) during flickering light stimulation in type 1 diabetes (T1D).METHODS: The study was performed in the period from 2008 to 2015 at the University Eye Clinic in Ljubljana. 41 p... | ["8-Hydroxy-2'-Deoxyguanosine", 'Adult', 'Aged', 'Blood Glucose', 'Deoxyguanosine', 'Diabetes Mellitus, Type 1', 'Female', 'Hemodynamics', 'Humans', 'Lighting', 'Lipids', 'Male', 'Middle Aged', 'Oxidative Stress', 'Retinal Artery'] | 27,815,934 | [['D03.633.100.759.590.454.240.500', 'D13.570.230.360.500', 'D13.570.583.454.240.500'], ['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['D03.633.100.759.590.454.240', 'D13.570.230.360', 'D13.570.583.454.240'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G09.330.380'], ['B01.050.150.900.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Idiopathic intrafascicular reentrant left ventricular tachycardia in an elite cyclist athlete. | A 32 year-old Caucasian male, an elite athlete, was admitted to the emergency department because of a sudden onset of palpitations which had lasted more than 12 hours and were associated with chest discomfort. He had a two-year history of recurrent stress-induced palpitations. He denied either episodes of syncope or an... | ['Adult', 'Bicycling', 'Cardiac Pacing, Artificial', 'Catheter Ablation', 'Electrocardiography', 'Heart Ventricles', 'Humans', 'Male', 'Physical Examination', 'Physical Exertion', 'Predictive Value of Tests', 'Tachycardia, Ventricular', 'Treatment Outcome'] | 19,950,094 | [['M01.060.116'], ['I03.450.642.845.140'], ['E02.331.200'], ['E02.808.750.500', 'E04.014.760.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600'], ['G11.427.683'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Epidemiology of diseases of the veins of the lower extremities in various climato-geographic conditions]. | An epidemiological study performed in different contrast climatic and geographic zones of the country has shown higher incidence of diseases of veins in regions of Siberia as compared to regions of Middle Asia. Risk factors of diseases of lower extremity veins occur 1.5-2 times more often in Siberia than in Middle Asia... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Climate', 'Female', 'Humans', 'Infant', 'Leg', 'Male', 'Middle Aged', 'Phlebitis', 'Siberia', 'Uzbekistan', 'Varicose Veins', 'Venous Insufficiency'] | 2,947,375 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['G16.500.275.071', 'N06.230.300.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A01.378.610.500'], ['M01.060.116.630'], ['C14.907.617.718', 'C14.907.940.740'], ['Z01.252.122.500.500'], ['Z01.252... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Microarrays: how many do you need? | We estimate the number of microarrays that is required in order to gain reliable results from a common type of study: the pairwise comparison of different classes of samples. We show that current knowledge allows for the construction of models that look realistic with respect to searches for individual differentially e... | ['Computational Biology', 'Data Interpretation, Statistical', 'Gene Expression Profiling', 'Genetic Variation', 'Models, Genetic', 'Oligonucleotide Array Sequence Analysis', 'Research Design', 'Selection Bias', 'Statistics, Nonparametric'] | 12,935,350 | [['H01.158.273.180', 'L01.313.124'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.393.332'], ['G05.365'], ['E05.599.395.397'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['E05.581.500', 'H01.770.644.728'], ['N05.715.350... | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Contrast-Induced Nephropathy: A Fact or Fiction in Lower Limb Revascularization? | INTRODUCTION: Contrast-induced nephropathy (CIN) is defined as an increase >25% of serum creatinine from baseline, occurring in 24-48 hours after exposure to contrast, while alternative explanations for renal impairment have been excluded. The volume administered directly relates to risk, increasing by 12% per 100 mL o... | ['Aged', 'Aged, 80 and over', 'Angiography', 'Biomarkers', 'Chi-Square Distribution', 'Contrast Media', 'Creatinine', 'Diabetes Mellitus', 'Endovascular Procedures', 'Female', 'Humans', 'Incidence', 'Kidney Diseases', 'Linear Models', 'Lower Extremity', 'Male', 'Middle Aged', 'Peripheral Arterial Disease', 'Predictive ... | 28,479,456 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.700.060', 'E01.370.370.050'], ['D23.101'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D27.505.259.500', 'D27.720.259'], ['D03.383.129.308.207'], ['C18.452.394.750', 'C19.246'], ['E04.100.814.529', 'E04.502.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Out-of-pocket health care expenditures among population groups in Iceland]. | OBJECTIVE: Out-of-pocket health expenditures affect access to health care. The study investigated trends in these expenditures, and whether certain population groups spent more than others.MATERIAL AND METHODS: The data come from two national health surveys among Icelandic adults from 1998 and 2006. The response rate w... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Chronic Disease', 'Dental Care', 'Disabled Persons', 'Drug Costs', 'Educational Status', 'Family Characteristics', 'Female', 'Financing, Personal', 'Health Care Surveys', 'Health Expenditures', 'Health Services Accessibility', 'Humans', 'Iceland', 'Income', 'Male', 'Middl... | 19,858,545 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C23.550.291.500'], ['E06.170', 'N02.421.240.190'], ['M01.150'], ['N03.219.151.400.350', 'N05.300.375.300'], ['N01.824.196'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Development of a Common Data Model Facilitating Clinical Decision-Making and Analyses. | Currently, the Common Data Model (CDM) for primary use (as distinct from models designed for secondary use) poorly supports clinical decision-making and medical process analyses. We designed a CDM featuring a search flow that identifies facts after defining the clinical process, and we make the data definition language... | ['Clinical Decision-Making', 'Delivery of Health Care'] | 31,438,208 | [['E01.055'], ['N04.590.374', 'N05.300']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The epithelial cell response to rotavirus infection. | Rotavirus is the most important worldwide cause of severe gastroenteritis in infants and young children. Intestinal epithelial cells are the principal targets of rotavirus infection, but the response of enterocytes to rotavirus infection is largely unknown. We determined that rotavirus infection of HT-29 intestinal epi... | ['Aging', 'Animals', 'Chemokines', 'Cytokines', 'DNA-Binding Proteins', 'Diarrhea', 'Enzyme Inhibitors', 'Epithelial Cells', 'Gene Expression Regulation', 'HT29 Cells', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'NF-kappa B', 'NF-kappa B p50 Subunit', 'Nuclear Proteins', 'Protein K... | 10,510,386 | [['G07.345.124'], ['B01.050'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.776.260'], ['C23.888.821.214'], ['D27.505.519.389'], ['A11.436'], ['G05.308'], ['A11.251.210.190.475', 'A11.251.860.180.475', 'A11.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Characteristics of continuous spike-and-wave during slow wave sleep syndrome in children]. | OBJECTIVE: Continuous spike-and-wave during slow wave sleep (CSWS) syndrome is one of the presentations of electrical status epilepticus during sleep (ESES). The purpose of this study was to investigate the characteristics of CSWS syndrome in children.METHODS: Between 2007 and 2009, a total of 778 nocturnal long-term o... | ['Adolescent', 'Child', 'Electroencephalography', 'Humans', 'Sleep', 'Status Epilepticus', 'Syndrome'] | 20,199,719 | [['M01.060.057'], ['M01.060.406'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.855', 'G11.561.803'], ['C10.597.742.785', 'C23.888.592.742.785'], ['C23.550.288.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Novelty and spatio-temporal heterogeneity in the bacterial diversity of hypersaline Lake Tebenquiche (Salar de Atacama). | Lake Tebenquiche is one of the largest saline water bodies in the Salar de Atacama at 2,500 m above sea level in northeastern Chile. Bacteria inhabiting there have to deal with extreme changes in salinity, temperature and UV dose (i.e., high environmental dissimilarity in the physical landscape). We analyzed the bacter... | ['Bacteria', 'Chile', 'Equipment Design', 'Genetic Variation', 'Geography', 'Hydrogen-Ion Concentration', 'Microscopy, Fluorescence', 'Models, Biological', 'RNA, Ribosomal', 'RNA, Ribosomal, 16S', 'Salts', 'Sequence Analysis, DNA', 'Temperature', 'Ultraviolet Rays', 'Water Microbiology'] | 18,347,752 | [['B03'], ['Z01.107.757.235'], ['E05.320'], ['G05.365'], ['H01.277.500'], ['G02.300'], ['E01.370.350.515.458', 'E05.595.458'], ['E05.599.395'], ['D13.444.735.686'], ['D13.444.735.686.670'], ['D01.786'], ['E05.393.760.700'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.30... | ['Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Evolutionary branching of dispersal strategies in structured metapopulations. | Dispersal polymorphism and evolutionary branching of dispersal strategies has been found in several metapopulation models. The mechanism behind those findings has been temporal variation caused by cyclic or chaotic local dynamics, or temporally and spatially varying carrying capacities. We present a new mechanism: spat... | ['Biological Evolution', 'Disasters', 'Ecosystem', 'Genetics, Population', 'Markov Chains', 'Models, Genetic', 'Polymorphism, Genetic', 'Population Density', 'Population Dynamics', 'Spatial Behavior'] | 12,181,601 | [['G05.045', 'G16.075'], ['N06.230.100'], ['G16.500.275.157', 'N06.230.124'], ['H01.158.273.343.335'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500', 'N06.850.520.830.996.500'], ['E05.599.395.397'], ['G05.365.795'], ['N01.22... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Quantitative analysis of zonulae occludentes between oviductal epithelial cells at diestrous and estrous stages in the mouse: freeze-fracture study. | The zonulae occludentes between oviductal epithelial cells were quantitatively analyzed at diestrous and estrous stages in the mouse, using the freeze-fracture technique. Zonulae occludentes were predominantly anastomosing at the diestrous stage, while they were predominantly parallel at the estrous stage. The lowest m... | ['Animals', 'Cilia', 'Epithelium', 'Estrus', 'Female', 'Fertilization', 'Freeze Fracturing', 'Lanthanum', 'Mice', 'Microscopy, Electron', 'Oviducts', 'Pregnancy'] | 6,684,407 | [['B01.050'], ['A11.284.180.165'], ['A10.272'], ['G08.686.195.500'], ['G08.686.784.277'], ['E01.370.225.500.620.620.260', 'E01.370.225.750.600.620.260', 'E05.200.500.620.620.260', 'E05.200.750.600.620.260'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.4... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurements of tibial rotation during a simulated pivot shift manoeuvre using a gyroscopic sensor. | PURPOSE: The pivot shift has been correlated with patient-reported outcomes and knee function following ACL injury and reconstruction. Tibial rotation has been recognized as an important component to the pivot shift motion path. However, few methodologies exist to quantify tibial rotation in the clinical setting. The p... | ['Adult', 'Anterior Cruciate Ligament', 'Biomechanical Phenomena', 'Cadaver', 'Humans', 'Joint Instability', 'Knee Joint', 'Middle Aged', 'Physical Examination', 'Rotation', 'Tibia', 'Young Adult'] | 24,817,161 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['A02.835.583.475'], ['M01.060.116.630'], ['E01.370.600'], ['G01.482.703'], ['A02.835.232.043.650.883'], ['M01.060.1... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition by anti-HLA class II monoclonal antibodies of monocyte-dependent T cell proliferation induced by monoclonal antibody OKT3. | The inhibitory effect of monoclonal antibodies (mAb) to monomorphic (locus-restricted and locus-shared) and polymorphic determinants of HLA class II antigens on the monocyte-dependent proliferation of T cells stimulated with mAb OKT3 has been studied. The effect appears to be specific, dose dependent, is not mediated b... | ['Antibodies, Monoclonal', 'Antigens, Surface', 'Cell Division', 'Dose-Response Relationship, Immunologic', 'HLA-D Antigens', 'Humans', 'Interleukin-2', 'Leukocytes, Mononuclear', 'Lymphocyte Activation', 'T-Lymphocytes', 'Tumor Necrosis Factor Receptor Superfamily, Member 7'] | 2,824,212 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G12.300'], ['D12.776.395.550.509.400', 'D12.776.543.550.440.400', 'D23.050.301.500.400.400', 'D23.050.301.500.450.400', 'D23.050.70... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of human sperm antigens reacting with antisperm antibodies from autologous sera and seminal plasma in a fertile population. | Immunoblotting techniques were used to characterize the reactivity of human sperm antigens with antisperm antibodies from a population of fertile individuals. In particular, sperm antigens of each subject were tested with the same subject's antisperm antibodies present in blood serum and seminal plasma in an attempt to... | ['Antibodies', 'Antigens', 'Humans', 'Immunoblotting', 'Male', 'Molecular Weight', 'Semen', 'Spermatozoa'] | 7,738,916 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D23.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['G02.494'], ['A12.200.732'], ['A05.360.490.890', 'A11.497.760']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae. | Ribonuclease P (RNase P) is an essential endoribonuclease that catalyzes the cleavage of the 5' leader of pre-tRNAs. In addition, a growing number of non-tRNA substrates have been identified in various organisms. RNase P varies in composition, as bacterial RNase P contains a catalytic RNA core and one protein subunit, ... | ['Introns', 'Mutation', 'Nucleic Acid Conformation', 'RNA Precursors', 'RNA, Untranslated', 'Ribonuclease P', 'Saccharomyces cerevisiae'] | 21,665,995 | [['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['G05.365.590'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.400.730', 'D13.444.735.640'], ['D13.444.735.790'], ['D08.811.277.352.700.350.711', 'D08.811.797.500', 'D12.776.157.725.500.625', 'D12.776.664.962.500.625'], ['B01.300.107.795.785.800', 'B01.300.93... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetics of the MRI contrast agent gadobutrol in common marmoset monkeys (Callithrix jacchus). | BACKGROUND: This study determined the pharmacokinetics of the contrast agent gadobutrol in marmosets by quantitative MRI to derive guidelines for neuroimaging protocols.METHODS: Local concentrations of gadobutrol were determined from consecutive gradient echo-based mapping of the relaxation rate R1 on a clinical 3T MRI... | ['Animals', 'Callithrix', 'Contrast Media', 'Female', 'Magnetic Resonance Imaging', 'Male', 'Organometallic Compounds'] | 27,417,149 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.150.150.114'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.825.500'], ['D02.691']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mast cell clones: a model for the analysis of cellular maturation. | Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function. We find that cloned mast cells express plasma membrane receptors (Fc epsilon R) that bi... | ['Animals', 'Butyrates', 'Cell Division', 'Cell Membrane', 'Cell Nucleus', 'Chondroitin Sulfates', 'Clone Cells', 'Cytoplasmic Granules', 'Heparin', 'Histamine', 'Mast Cells', 'Mice', 'Receptors, IgE', 'Receptors, Immunologic'] | 6,216,259 | [['B01.050'], ['D02.241.081.114', 'D10.251.400.143'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.149'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D09.698.373.200.300'], ['A11.251.353'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['D09.698.373.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Damage modes in dental layer structures. | Natural teeth (enamel/dentin) and most restorations are essentially layered structures. This study examines the hypothesis that coating thickness and coating/substrate mismatch are key factors in the determination of contact-induced damage in clinically relevant bilayer composites. Accordingly, we study crack patterns ... | ['Aluminum Oxide', 'Aluminum Silicates', 'Coated Materials, Biocompatible', 'Composite Resins', 'Crowns', 'Dental Materials', 'Dental Porcelain', 'Dental Restoration Failure', 'Dental Stress Analysis', 'Finite Element Analysis', 'Humans', 'In Vitro Techniques', 'Materials Testing', 'Mechanics', 'Models, Structural', 'P... | 10,326,733 | [['D01.056.050', 'D01.650.550.050'], ['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D25.130.420', 'J01.637.051.130.420'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.780.346.250', 'E07.695... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Is a Surgical Approach Justified in Metachronous Krukenberg Tumor from Gastric Cancer? A Systematic Review. | BACKGROUND: The treatment of metachronous Krukenberg tumor (mKT) from gastric cancer remains unexplored. We performed a literature review to evaluate whether or not surgical treatment improves survival.METHODS: A systematic review according to PRISMA guidelines was performed. Studies reporting on patients who underwent... | ['Female', 'Humans', 'Krukenberg Tumor', 'Neoplasms, Second Primary', 'Ovarian Neoplasms', 'Stomach Neoplasms'] | 30,205,375 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.470.200.025.415.410', 'C04.557.470.590.415.410'], ['C04.692'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proteolytic formation and properties of a fragment of protein C containing the gamma-carboxyglutamic acid rich domain and the EGF-like region. | The function of the epidermal growth factor (EGF) like domains in the vitamin K dependent plasma proteins is largely unknown. In order to elucidate the function of these domains in protein C, we have devised a method to isolate the EGF-like region from the light chain connected to the NH2-terminal region, containing th... | ['1-Carboxyglutamic Acid', 'Animals', 'Blood Coagulation', 'Calcium', 'Cattle', 'Epidermal Growth Factor', 'Molecular Structure', 'Peptide Fragments', 'Protein Binding', 'Protein C', 'Spectrometry, Fluorescence', 'Structure-Activity Relationship'] | 2,337,587 | [['D02.241.081.901.400', 'D12.125.067.625.174', 'D12.125.119.409.174'], ['B01.050'], ['G09.188.390.150'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['G02.111.570', 'G02.466'], ['D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement of readiness to reduce driving speed: a pilot study. | Speeding is a preventable risky behavior that contributes to risk of accident. Readiness to change reflects an individual's recognition of and desire to change behavior. No measure to identify readiness to change has yet been validated for speeding. The Readiness to Change Questionnaire appraises readiness to change dr... | ['Adult', 'Automobile Driving', 'Humans', 'Male', 'Motivation', 'Pilot Projects', 'Principal Component Analysis', 'Psychometrics', 'Reproducibility of Results', 'Risk-Taking', 'Surveys and Questionnaires'] | 21,323,134 | [['M01.060.116'], ['I03.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.318.740.562'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Meal-induced thermogenesis and obesity: is a fat meal a risk factor for fat gain in children? | Diet composition, in particular fat intake, has been suggested to be a risk factor for obesity in humans. Several mechanisms may contribute to explain the impact of fat intake on fat gain. One factor may be the low thermogenesis induced by a mixed meal rich in fat. In a group of 11 girls (10.1 +/- 0.3 yr), 6 obese (bod... | ['Adipose Tissue', 'Child', 'Dietary Carbohydrates', 'Dietary Fats', 'Eating', 'Energy Metabolism', 'Female', 'Humans', 'Obesity', 'Oxidation-Reduction', 'Reference Values', 'Respiration', 'Rest', 'Risk Factors', 'Thermogenesis'] | 11,232,003 | [['A10.165.114'], ['M01.060.406'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G07.203.650.283', 'G10.261.330'], ['G03.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.10... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Dopamine depletion impairs gait automaticity by altering cortico-striatal and cerebellar processing in Parkinson's disease. | Impairments in motor automaticity cause patients with Parkinson's disease to rely on attentional resources during gait, resulting in greater motor variability and a higher risk of falls. Although dopaminergic circuitry is known to play an important role in motor automaticity, little evidence exists on the neural mechan... | ['Attention', 'Brain Mapping', 'Cerebellum', 'Cerebral Cortex', 'Corpus Striatum', 'Dopamine', 'Gait', 'Humans', 'Levodopa', 'Magnetic Resonance Imaging', 'Motor Activity', 'Parkinson Disease', 'Virtual Reality'] | 28,263,926 | [['F02.830.104.214'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E01.370.600.250', 'G11.427.410.568.... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Evaluation of two kinds of enzyme linked immunosorbent assay method for clonorchiasis]. | In this present study, adult worm antigen of Clonorchis sinensis and the indirect and double sandwich enzyme linked immunosorbent assay (ELISA) were used to detect the serum antibody of clonorchiasis patients from the endemic area of Miao-Li county. The results of indirect ELISA revealed a good correlation between the ... | ['Animals', 'Antibodies, Helminth', 'Clonorchiasis', 'Clonorchis sinensis', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Praziquantel'] | 1,342,001 | [['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['C01.610.335.865.148'], ['B01.050.500.500.736.715.520.210'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.40... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relaxation induced by S-nitroso-glutathione and S-nitroso-N-acetylcysteine in rat aorta is not related to nitric oxide production. | S-nitroso-glutathione (GSNO) and S-nitroso-N-acetylcysteine (NACysNO) are nitrosothiols that release nitric oxide (NO) and mimic the effects of endogenous NO. This study investigated the relaxation induced by GSNO and NACysNO in rat aorta and the relation between relaxation and NO formation. Both compounds at concentra... | ['Acetylcysteine', 'Animals', 'Aorta, Thoracic', 'Endothelium, Vascular', 'Enzyme Inhibitors', 'Glutathione', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Male', 'Muscle Relaxation', 'Muscle, Smooth, Vascular', 'Nitric Oxide', 'Nitroso Compounds', 'Oxadiazoles', 'Phenylephrine', 'Potassium Channel Blockers', '... | 11,454,932 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['B01.050'], ['A07.015.114.056.372'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.519.389'], ['D12.644.456.448'], ['G02.300'], ['E05.481'], ['G11.427.494.554'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D01.339.387', 'D01.625.550.500', 'D01.625.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacteriocin-encoding genes and ExPEC virulence determinants are associated in human fecal Escherichia coli strains. | BACKGROUND: A set of 1181 E. coli strains of human fecal origin isolated in the South Moravia region of the Czech Republic was collected during the years 2007-2010. Altogether, 17 virulence determinants and 31 bacteriocin-encoding genes were tested in each of them.RESULTS: The occurrence of bacteriocin-encoding genes w... | ['Bacteriocins', 'Czech Republic', 'DNA, Bacterial', 'Escherichia coli', 'Feces', 'Female', 'Genes, Bacterial', 'Genotype', 'Humans', 'Male', 'Molecular Sequence Data', 'Sequence Analysis, DNA', 'Virulence Factors'] | 24,774,171 | [['D12.776.097.151', 'D12.776.543.695.110'], ['Z01.542.248.395'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A12.459'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.6... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Doctors' death experience and attitudes towards death, euthanasia and informing terminal patients. | In daily practice physicians are professionally obliged to interpret ethical precepts and laws in emergency situations under extreme pressure when resuscitation measures leave little or no time to consider deontological issues. The extent to which extraprofessional experiences influence physicians' attitudes towards de... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Attitude of Health Personnel', 'Attitude to Death', 'Female', 'Humans', 'Male', 'Middle Aged', 'Physician-Patient Relations', 'Stress, Psychological', 'Terminal Care', 'Truth Disclosure', 'Withholding Treatment'] | 1,302,770 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['F01.100.125', 'N05.300.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F01.145.126.990', 'F02.830.900'], ['E02.760.905', 'N02.421.585.905'], ['F01.829.401.046.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
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