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Long pentraxin-3 inhibits FGF8b-dependent angiogenesis and growth of steroid hormone-regulated tumors. | Fibroblast growth factor-8b (FGF8b) exerts nonredundant autocrine/paracrine functions in steroid hormone-regulated tumors. Previous observations had shown that the soluble pattern recognition receptor long pentraxin-3 (PTX3) is a natural selective antagonist for a restricted number of FGF family members, inhibiting FGF... | ['Androgens', 'Angiogenesis Inhibitors', 'Animals', 'C-Reactive Protein', 'CHO Cells', 'Cattle', 'Cell Line', 'Cell Proliferation', 'Chick Embryo', 'Cricetinae', 'Fibroblast Growth Factor 8', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, SCID', 'Neoplasms', 'Neovascula... | 21,764,903 | [['D27.505.696.399.472.161'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NADPH-diaphorase neurons in the retina of the hamster. | NADPH-diaphorase-positive neurons have been demonstrated in the inner nuclear layer and ganglion cell layer of the retina of different mammalian species, but so far no experiments have been conducted to identify whether these cells are amacrine cells and/or retinal ganglion cells. We attempted to solve this problem by ... | ['Amino Acid Oxidoreductases', 'Animals', 'Cricetinae', 'Dendrites', 'Horseradish Peroxidase', 'Male', 'Mesocricetus', 'Microscopy, Fluorescence', 'Microspheres', 'NADPH Dehydrogenase', 'Nerve Degeneration', 'Neurons', 'Nitric Oxide Synthase', 'Optic Nerve', 'Retina', 'Retinal Ganglion Cells'] | 7,534,316 | [['D08.811.682.664.500'], ['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['D08.811.682.732.512'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['E01.370.350.515.458', 'E05.595.458'], ['E07.565'], ['D08.811.682.608.550'], ['C23.550.737'], ['A08.675', 'A11... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Consideration of therapeutic choice for grade 3 superficial bladder cancer]. | Between January, 1977 and December, 1994, 90 patients with grade 3 (G3) superficial bladder cancer were treated at Yokohama City University Hospital, Yokohama Municipal Hospital and Kanagawa Cancer Center. These patients were clinically observed. The prognostic factors of the patients with G3 superficial bladder tumors... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Carcinoma, Transitional Cell', 'Cystectomy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Survival Rate', 'Urinary Bladder Neoplasms'] | 8,918,660 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.430'], ['E04.950.774.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E01.789'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.97... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changes in the susceptibility of Actinobacillus pleuropneumoniae to antimicrobial agents in Quebec (1981-1986). | An important reduction in the in vitro efficacy of spectinomycin and chloramphenicol was recorded between 1981 and 1986 against the causal agent of porcine pleuropneumonia Actinobacillus. Antimicrobial susceptibility tests were carried out by use of Kirby-Bauer disk diffusion technique on a total of 723 isolates of Act... | ['Actinobacillus', 'Actinobacillus Infections', 'Animals', 'Anti-Bacterial Agents', 'In Vitro Techniques', 'Lung', 'Microbial Sensitivity Tests', 'Pleuropneumonia', 'Quebec', 'Swine', 'Swine Diseases'] | 3,170,322 | [['B03.440.450.009', 'B03.660.250.550.050'], ['C01.150.252.400.700.030'], ['B01.050'], ['D27.505.954.122.085'], ['E05.481'], ['A04.411'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['C01.748.582.473', 'C01.748.610.473', 'C08.381.677.473', 'C08.528.735.473', 'C08.730.582.473', 'C08.730.610.473'], ['Z... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. | Mutations in chromatin modifier genes are frequently associated with neurodevelopmental diseases. We herein demonstrate that the chromodomain helicase DNA-binding protein 7 (Chd7), frequently associated with CHARGE syndrome, is indispensable for normal cerebellar development. Genetic inactivation of Chd7 in cerebellar ... | ['Animals', 'Brain', 'Cell Differentiation', 'Cerebellum', 'Chromatin', 'DNA-Binding Proteins', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Humans', 'Mammals', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mice, Transgenic', 'Neurons'] | 28,317,875 | [['B01.050'], ['A08.186.211'], ['G04.152'], ['A08.186.211.132.810.428.200'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.260'], ['E05.393.332'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649'], ['B01.050.050.199.520.520.420', 'B01.05... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk of cervical cancer in symptomatic women aged ?40 in primary care: A case-control study using electronic records. | There are approximately 3,000 new UK diagnoses of cervical cancer annually, with many women presenting symptomatically. We aimed to identify and quantify features of cervical cancer in primary care in a case-control study in the UK. Putative features of cervical cancer were identified, and odd ratios and positive predi... | ['Abdominal Pain', 'Adult', 'Age of Onset', 'Aged', 'Case-Control Studies', 'Diagnosis, Differential', 'Early Detection of Cancer', 'Electronic Health Records', 'England', 'Female', 'Hematuria', 'Hemoglobinopathies', 'Humans', 'Leukocyte Count', 'Menstruation Disturbances', 'Middle Aged', 'Risk Factors', 'Urinary Tract... | 28,474,381 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.171'], ['E01.390.500'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of functional catechol-O-methyltransferase Val158Met polymorphism on physical aggression. | Genetic and psychological analysis of the relationships between catechol-O-methyltransferase Val158Met polymorphism and various types of aggressiveness was performed in 114 women. Dispersion analysis revealed significant association of ValVal genotype with elevated physical aggression. | ['Adolescent', 'Aggression', 'Catechol O-Methyltransferase', 'Child', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Methionine', 'Personality', 'Polymorphism, Single Nucleotide', 'Valine', 'Young Adult'] | 19,024,004 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['D08.811.913.555.500.250'], ['M01.060.406'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['F01.752'], ['G05.365.795.598'], ['D12.125.070.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sex differences in cocaine-induced behavioral sensitization. | To further understand how sex differences affect the development and maintenance of sensitization, 48 adult Fischer rats (24 female and 24 male) received chronic administration (14 days) of cocaine (15 mg/kg, i.p.) or saline or a challenge dose (7 days after chronic cocaine administration). Sex differences were observe... | ['Animals', 'Behavior, Animal', 'Cocaine', 'Corticosterone', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Injections, Intraperitoneal', 'Locomotion', 'Male', 'Rats', 'Rats, Inbred F344', 'Sex Factors', 'Stereotyped Behavior'] | 11,785,661 | [['B01.050'], ['F01.145.113'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E02.319.267.530.490'], ['G07.568.500', 'G11.427.410.568'], ['B01.050.150.900.649... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A weekly regimen with dose escalation of doxorubicin for patients with advanced Hodgkin's lymphoma: results of a phase II study of the Groupe d'Etudes des Lymphomes de l'Adulte (GELA). | This multicenter phase II study assessed the feasibility and efficacy of a weekly chemotherapy regimen with a moderately escalated dose of doxorubicin administered over 16 weeks, followed by radiation therapy (RT) to bulky sites. From July 1996 to February 1998, 44 untreated patients with stage IIIB-IV Hodgkin's lympho... | ['Adolescent', 'Adult', 'Antibiotics, Antineoplastic', 'Disease-Free Survival', 'Doxorubicin', 'Drug Administration Schedule', 'Female', 'Hodgkin Disease', 'Humans', 'Male', 'Middle Aged', 'Recurrence', 'Risk Factors', 'Time Factors', 'Treatment Outcome'] | 17,454,626 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.248.106'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E02.319... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
IGFBP5 mediates high glucose-induced cardiac fibroblast activation. | This study examined whether IGF-binding protein 5 (IGFBP5) is involved in the high glucose-induced deteriorating effects in cardiac cells. Cardiac fibroblasts and cardiomyocytes were isolated from the hearts of 1- to 3-day-old Sprague Dawley rats. Treatment of fibroblasts with 25 mM glucose increased the number of cell... | ['Animals', 'Blotting, Western', 'Cells, Cultured', 'Fibroblasts', 'Flow Cytometry', 'Glucose', 'Immunoprecipitation', 'Insulin-Like Growth Factor Binding Protein 5', 'Insulin-Like Growth Factor I', 'Male', 'Myocardium', 'Rats', 'Rats, Sprague-Dawley', 'Real-Time Polymerase Chain Reaction'] | 23,417,767 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['A11.329.228'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biochemical effects of mutations in the gene encoding the alpha subunit of eukaryotic initiation factor (eIF) 2B associated with Vanishing White Matter disease. | BACKGROUND: Leukoencephalopathy with Vanishing White Matter (VWM) is an autosomal recessive disorder caused by germline mutations in the genes EIF2B1-5, which encode the 5 subunits of the eukaryotic translation initiation factor eIF2B. To date, analysis of the biochemical effects of mutations in the EIF2B2-5 genes has ... | ['Blotting, Western', 'Chromatography, Affinity', 'Eukaryotic Initiation Factor-2B', 'HEK293 Cells', 'Humans', 'Leukoencephalopathies', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Mutation', 'Plasmids', 'Protein Binding', 'Protein Subunits'] | 26,285,592 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.181.400.170'], ['D12.644.360.325.300.050', 'D12.776.476.325.300.050', 'D12.776.835.725.868.374'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.695'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radiographic abnormalities in cats with feline bronchial disease and intra- and interobserver variability in radiographic interpretation: 40 cases (1999-2006). | OBJECTIVE: To determine prevalence of various radiographic signs in cats with feline bronchial disease (FBD) and evaluate intra- and interobserver variability in radiographic interpretation for examiners with variable degrees of experience in radiographic interpretation.DESIGN: Retrospective case series.ANIMALS: 40 cat... | ['Animals', 'Bronchial Diseases', 'Cat Diseases', 'Cats', 'Clinical Competence', 'Diagnosis, Differential', 'Female', 'Male', 'Observer Variation', 'Radiography, Thoracic', 'Reproducibility of Results', 'Retrospective Studies', 'Sensitivity and Specificity', 'Severity of Illness Index'] | 19,210,258 | [['B01.050'], ['C08.127'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E01.171'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E01.370.350.700.730'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N... | ['Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Inherent variations in the cellular events at the site of amputation orchestrate scar-free wound healing in the tail and scarred wound healing in the limb of lizard Hemidactylus flaviviridis. | Lizards are unique in having both-regeneration competent (tail) as well as non-regenerating appendages (limbs) in adults. They therefore present an appropriate model for comparing processes underlying regenerative repair and nonregenerative healing after amputation. In the current study, we use northern house gecko Hem... | ['Amputation', 'Animals', 'Cell Proliferation', 'Cicatrix', 'Extremities', 'Immunomodulation', 'Lizards', 'Models, Animal', 'Neovascularization, Physiologic', 'Regeneration', 'Regenerative Medicine', 'Reptilian Proteins', 'Tail', 'Vascular Endothelial Growth Factor A', 'Wound Healing'] | 30,054,965 | [['E04.555.080'], ['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['A01.378'], ['E02.095.465', 'G12.535'], ['B01.050.150.900.833.393'], ['E05.598'], ['G09.330.630'], ['G16.762'], ['H02.403.750'], ['D12.776.831'], ['A13.895'], ['D12.644.276.100.800.200', 'D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Rat beta-nerve growth factor sequence and site of synthesis in the adult hippocampus. | A rat beta-nerve growth factor (NGF) genomic sequence encoding the entire 3' exon of preproNGF was cloned, and its nucleotide sequence was determined. Rat NGF shows very high homology with other known NGFs in both the prepropeptide and the 3' untranslated regions. The presumptive signal sequence, the cysteine residues ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cattle', 'Female', 'Hippocampus', 'Humans', 'Molecular Sequence Data', 'Nerve Growth Factors', 'Nucleic Acid Hybridization', 'Protein Precursors', 'Rats', 'Rats, Inbred Strains', 'Sequence Homology, Nucleic Acid'] | 3,184,206 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.500.380.271'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D12.644.276.860', 'D12.776.467... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Anti-tumour activity and bone marrow toxicity of chloroethylnitrosocarbamoyl-amino acid derivatives. | The anti-tumour activity of a series of chloroethylnitrosoureas derived from the amino acids alanine and glycine was examined in 3 transplantable adenocarcinomas of the mouse colon. In addition, bone marrow toxicity was assessed using a spleen colony forming unit assay. A spectrum of differing activity-toxicity pattern... | ['Amino Acids', 'Animals', 'Antineoplastic Agents', 'Bone Marrow', 'Colonic Neoplasms', 'Ethylnitrosourea', 'Mice', 'Neoplasm Transplantation', 'Structure-Activity Relationship'] | 1,580,552 | [['D12.125'], ['B01.050'], ['D27.505.954.248'], ['A15.382.216'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D02.065.950.594.310', 'D02.654.692.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.624'], ['G02.111.83... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efflux of cyclic nucleotides from rat pineal: release of guanosine 3',5'-monophosphate from sympathetic nerve endings. | Potassium and norepinephrine stimulate the efflux of adenosine 3',5'-monophosphate (cyclic AMP) and guanosine 3',5'-monophosphate (cyclic GMP) from intact pineal glands. The postsynaptic beta-adrenergic receptor mediates the efflux of cyclic AMP. In contrast, the efflux of cyclic GMP requires calcium and intact nerve e... | ["3',5'-Cyclic-AMP Phosphodiesterases", 'Animals', 'Calcium', 'Cyclic AMP', 'Cyclic GMP', 'Kinetics', 'Male', 'Nerve Endings', 'Norepinephrine', 'Nucleotides, Cyclic', 'Pineal Gland', 'Potassium', 'Rats', 'Receptors, Adrenergic, beta', 'Stereoisomerism', 'Sympathetic Nervous System', 'Synaptic Membranes'] | 195,336 | [['D08.811.277.352.640.150', 'D12.644.360.008', 'D12.776.476.008'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exploring the ecological validity and variability of a 10-min bout of wheeling. | PURPOSE: To determine the ecological validity of using able-bodied participants to perform a 10-min wheeling trial by (1) evaluating changes in biomechanics over the trial in manual wheelchair users and able-bodied participants na?ve to wheeling and (2) describing differences in changes and variability between groups.M... | ['Adult', 'Biomechanical Phenomena', 'Disabled Persons', 'Female', 'Humans', 'Male', 'Middle Aged', 'Spinal Cord Injuries', 'Wheelchairs'] | 28,485,185 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.854.763', 'C10.900.850', 'C26.819'], ['E07.796.980']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A biochemical assessment of the glucocorticoid function of the adrenal cortex in patients with occupational bronchial asthma and asthmatic bronchitis]. | The article contains a study of the basal level and the circadian rhythm of the hydrocortisone secretion in patients with occupational bronchial asthma and asthmatic bronchitis. Relationships were established between the hydrocortisone secretion levels and severity of the clinical course. Circadian rythm disorders resu... | ['Adrenal Cortex', 'Asthma', 'Bronchitis', 'Circadian Rhythm', 'Glucocorticoids', 'Humans', 'Hydrocortisone', 'Occupational Diseases', 'Occupational Exposure'] | 1,810,819 | [['A06.300.071.140'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['G07.180.562.190'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Preliminary research on preparation of porcine bladder acellular matrix graft for tissue engineering applications]. | OBJECTIVE: To investigate the preparation method of porcine bladder acellular matrix graft (BAMG) and evaluate the feasibility of using BAMG as biomaterial scaffold to construct tissue engineering bladder.METHODS: Bladders were harvested from adult pigs at a slaughterhouse and were decellularized by the method of enzym... | ['Animals', 'Cells, Cultured', 'Extracellular Matrix', 'Male', 'Rabbits', 'Swine', 'Tissue Engineering', 'Tissue Scaffolds', 'Urinary Bladder'] | 16,324,303 | [['B01.050'], ['A11.251'], ['A11.284.295.310'], ['B01.050.150.900.649.313.968.700'], ['B01.050.150.900.649.313.500.880'], ['E05.481.500.311.500', 'J01.293.069.249.500'], ['E07.206.627', 'E07.695.825'], ['A05.810.890']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A novel sensor for cephalosporins based on electrocatalytic oxidation by poly(o-anisidine)/SDS/Ni modified carbon paste electrode. | In this work for first time, the electrocatalytic oxidations of some cephalosporins were carried out by poly(o-anisidine)/SDS/Ni modified carbon paste electrode using cyclic voltammetry, chronoamperometry and chronocoulometry methods. At first, poly(o-anisidine) was formed by cyclic voltammetry in monomer solution cont... | ['Aniline Compounds', 'Biosensing Techniques', 'Catalysis', 'Cefixime', 'Ceftizoxime', 'Ceftriaxone', 'Cephalosporins', 'Chemistry Techniques, Analytical', 'Electrochemistry', 'Electrodes', 'Models, Chemical', 'Nickel', 'Oxygen', 'Sodium Dodecyl Sulfate', 'Solvents'] | 20,441,933 | [['D02.092.146'], ['E05.601.043'], ['G02.130'], ['D02.065.589.099.249.190.190.115', 'D02.886.665.074.190.190.115', 'D03.633.100.300.249.190.190.115'], ['D02.065.589.099.249.190.190.145', 'D02.886.665.074.190.190.145', 'D03.633.100.300.249.190.190.145'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A marine-derived acidic oligosaccharide sugar chain specifically inhibits neuronal cell injury mediated by beta-amyloid-induced astrocyte activation in vitro. | In Alzheimer's disease (AD), beta-amyloid (Abeta) plaques are surrounded by activated astrocytes and microglia. A growing body of evidence suggests that these activated astrocytes contribute to neurotoxicity through the induction of inflammatory cytokines and the production of oxidative stress mediators. Thus, a compou... | ['Alzheimer Disease', 'Amyloid beta-Peptides', 'Animals', 'Animals, Newborn', 'Astrocytes', 'Calcium Signaling', 'Cells, Cultured', 'Culture Media, Conditioned', 'Cytokines', 'Encephalitis', 'Gliosis', 'Interleukin-6', 'Mannans', 'Nerve Degeneration', 'Oxidative Stress', 'Rats', 'Rats, Wistar', 'Tumor Necrosis Factor-a... | 17,427,283 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['B01.050.050.282'], ['A08.637.200', 'A11.650.200'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['D12.6... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through beta-catenin-independent signaling. | Despite studies based on deletion or activation of intracellular components of the canonical Wingless related (Wnt) pathway, the role of Wnts in hematolymphopoiesis remains controversial. Using gain-of-function and loss-of-function models, we found that Wnt4 differentially affected diverse subsets of hematopoietic stem... | ['Animals', 'Cell Differentiation', 'Flow Cytometry', 'Hematopoietic Stem Cells', 'Immunoblotting', 'Mice', 'Multipotent Stem Cells', 'Reverse Transcriptase Polymerase Chain Reaction', 'Signal Transduction', 'Thymus Gland', 'Wnt Proteins', 'Wnt4 Protein', 'beta Catenin'] | 18,617,424 | [['B01.050'], ['G04.152'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['E05.478.566.320', 'E05.601.470.320'], ['B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of tensiomyographic neuromuscular characteristics between muscles of the dominant and non-dominant lower extremity in male soccer players. | PURPOSE: Tensiomyography (TMG) has been used to assess neuromuscular characteristics of muscles of the lower extremity in soccer players. However, the effects of lower extremity dominance on TMG characteristics in this population have not been reported to date. The purpose of this study was to compare the TMG neuromusc... | ['Adult', 'Cross-Sectional Studies', 'Electromyography', 'Functional Laterality', 'Humans', 'Lower Extremity', 'Male', 'Muscle, Skeletal', 'Soccer', 'Young Adult'] | 25,236,679 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.405.255', 'E01.370.530.255'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610'], ['A02.633.567', 'A10.690.552.500'], ['I03.450.642.845.800'], ['M01.060.116.81... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Tarsal tunnel syndrome]. | The tarsal tunnel syndrome shall be discussed in view of the available literature as well as experience derived from 58 operative procedures. A compression syndrome of the tibial nerve should always be considered in cases of pain of the foot after trauma to the lower extremity and foot. The etiology, clinical presentat... | ['Follow-Up Studies', 'Humans', 'Tarsal Tunnel Syndrome'] | 3,807,559 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829.500.700.800', 'C10.668.829.550.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Asociaci?n del estado hormonal con el riesgo cardiovascular evaluado por Globorisk en mujeres mexicanas]. | Introduction: Cardiovascular disease is the main cause of mortality worldwide. In women, its incidence increases at the sixth decade of life, coinciding with postmenopause. Whether this effect is due to menopause-related hormonal changes is not known.Objective: To evaluate the differences in cardiovascular risk in pre-... | ['Adult', 'Cardiovascular Diseases', 'Cholesterol', 'Cholesterol, HDL', 'Cross-Sectional Studies', 'Female', 'Humans', 'Metabolic Syndrome', 'Mexico', 'Middle Aged', 'Postmenopause', 'Premenopause', 'Prevalence', 'Risk Factors', 'Triglycerides', 'Waist Circumference'] | 30,532,111 | [['M01.060.116'], ['C14'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Temperature-modulated quenching of quantum dots covalently coupled to chain ends of poly(N-isopropyl acrylamide) brushes on gold. | A thermo-responsive polymer/quantum dot platform based on poly(N-isopropyl acrylamide) (PNIPAM) brushes 'grafted from' a gold substrate and quantum dots (QDs) covalently attached to the PNIPAM layer is presented. The PNIPAM brushes are grafted from the gold surface using an iniferter-initiated controlled radical polyme... | ['Acrylic Resins', 'Crystallization', 'Gold', 'Luminescent Measurements', 'Macromolecular Substances', 'Materials Testing', 'Molecular Conformation', 'Nanotechnology', 'Particle Size', 'Quantum Dots', 'Surface Properties', 'Temperature'] | 19,420,613 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['E05.196.300', 'G02.171'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E05.196.712.516'], ['D05'], ['E05.570'], ['G02.111.570.820'], ['H01.603', 'J01.897.520.600'], ['G02.712'], ['E07.705', 'J01.637.512.600.650'], ['G02.86... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
The relaxation induced by uroguanylin and the expression of natriuretic peptide receptors in human corpora cavernosa. | INTRODUCTION: Receptors for natriuretic peptides have been demonstrated as potential targets for the treatment of male erectile dysfunction.AIM: This study investigates the relaxant effects of the atrial natriuretic peptide (ANP) and uroguanylin (UGN), and expression of natriuretic peptide receptors on strips of human ... | ['Adolescent', 'Adult', 'Atrial Natriuretic Factor', 'Cadaver', 'Cyclic AMP', 'Cyclic GMP', 'Cyclic Nucleotide Phosphodiesterases, Type 5', 'Erectile Dysfunction', 'Guanylate Cyclase', 'Humans', 'Male', 'Middle Aged', 'Muscle Relaxation', 'Muscle, Smooth', 'Natriuretic Peptides', 'Penis', 'Receptors, Atrial Natriuretic... | 20,102,442 | [['M01.060.057'], ['M01.060.116'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['C23.550.260.224'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D08.811.277.352.64... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Proteome analysis of recombinant Escherichia coli producing human glucagon-like peptide-1. | The proteomic response of recombinant Escherichia coli producing human glucagon-like peptide-1 was analyzed by two-dimensional gel electrophoresis. Protein spots in two-dimensional gel could be identified by using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and their expression profiles... | ['Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Glucagon-Like Peptide 1', 'Humans', 'Proteome', 'Proteomics', 'Recombinant Proteins', 'Reproducibility of Results', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Time Factors'] | 17,049,938 | [['E05.196.401.250', 'E05.301.300.230'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D06.472.317.680.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.817'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Evidence-based periodontal treatment. I. A strategy for clinical decisions. | This article is first in a series of reports describing an evidence-based approach for evaluating information associated with periodontal treatment. Two main differences distinguish this approach from the traditional one, which is based largely on clinical experience. The evidence-based approach requires that investiga... | ['Databases, Bibliographic', 'Decision Making', 'Decision Support Techniques', 'Humans', 'MEDLARS', 'Patient Care Planning', 'Periodontal Diseases', 'Periodontics', 'Practice Guidelines as Topic', "Practice Patterns, Physicians'"] | 7,591,525 | [['L01.313.500.750.300.188.300', 'L01.470.750.500'], ['F02.463.785.373'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280.710', 'L01.313.500.750.300.710'], ['N04.590.233.624'], ['C07.465.714'], ['E06.721', 'H02.163.876.623'], ['N04.761.700.350.650', 'N05.700.35... | ['Information Science [L]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Effect of salinity on growth of green alga Botryococcus braunii and its constituents. | Growth of Botryococcus braunii (race 'A') and production of its constituents viz, hydrocarbon, carbohydrate, fatty acid, and carotenoids were influenced by different levels of salinity. Under salinity at 34 mM and 85 mM, 1.7-2.25-fold increase in the relative proportion of palmitic acid and two fold increase in oleic a... | ['Biomass', 'Carbohydrate Metabolism', 'Carotenoids', 'Chlorophyll', 'Chlorophyta', 'Phosphates', 'Sodium Chloride', 'Time Factors', 'Water'] | 16,782,327 | [['G16.500.275.157.100', 'N06.230.124.100'], ['G02.111.158', 'G03.191'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['B01.650.940.150'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.6... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Improved production of 1-deoxynojirymicin in Escherichia coli through metabolic engineering. | Azasugars, such as 1-deoxynojirymicin (1-DNJ), are associated with diverse pharmaceutical applications, such as antidiabetic, anti-obesity, anti-HIV, and antitumor properties. Different azasugars have been isolated from diverse microbial and plant sources though complicated purification steps, or generated by costly ch... | ['1-Deoxynojirimycin', 'Bacterial Proteins', 'Biosynthetic Pathways', 'Cloning, Molecular', 'Culture Media', 'DNA, Bacterial', 'Escherichia coli', 'Fermentation', 'Fructosephosphates', 'Genes, Bacterial', 'Metabolic Engineering', 'Synthetic Biology'] | 29,796,897 | [['D02.491.567.500.033', 'D03.132.014', 'D03.383.621.300.033', 'D09.553.500.033'], ['D12.776.097'], ['G02.111.098', 'G03.493.100'], ['E05.393.220'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.158.249', 'G03.191.249'], ['D09.894.417.313'], ['G05... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Quantification of excitatory receptive fields of complex neurones in cat striate cortex. | Excitatory receptive field (ERF) response profiles and length summation functions were derived from complex neurones in cat striate cortex. Measured length summation was compared with summation predicted from integration over ERF profiles. In a minority of neurones, measured and predicted summation were well matched. I... | ['Animals', 'Cats', 'Functional Laterality', 'Neurons', 'Photic Stimulation', 'Visual Cortex', 'Visual Fields'] | 7,925,792 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['F02.830.297.425', 'G11.561.225.425'], ['A08.675', 'A11.671'], ['E05.723.729'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953'], ['F02.463.593.932.934', 'G14.950']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensitivity and reversibility of Ca-dependent inhibition of the (Na+ + K+)-ATPase of human red blood cells. | The sensitivity of the (Na+ + K+)-ATPase to inhibition by Ca was increased 30-fold by a partially purified extract of human red cell hemolysate. The hemolysate fraction reduced the concentration of free Ca required for 50% inhibition from 30 microM to approx. 1 microM. Ca-dependent inhibition of the (Na+ + K+)-ATPase i... | ['Calcium', 'Calcium-Transporting ATPases', 'Erythrocytes', 'Hemolysis', 'Humans', 'Sodium-Potassium-Exchanging ATPase'] | 2,982,403 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.40... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protection of armadillo/â-Catenin by armless, a novel positive regulator of wingless signaling. | The Wingless (Wg/Wnt) signaling pathway is essential for metazoan development, where it is central to tissue growth and cellular differentiation. Deregulated Wg pathway activation underlies severe developmental abnormalities, as well as carcinogenesis. Armadillo/â-Catenin plays a key role in the Wg transduction cascade... | ['Adaptor Proteins, Signal Transducing', 'Adaptor Proteins, Vesicular Transport', 'Animals', 'Armadillo Domain Proteins', 'Autophagy-Related Proteins', 'Carrier Proteins', 'Cell Cycle Proteins', 'Drosophila', 'Drosophila Proteins', 'Gene Expression Regulation, Developmental', 'HEK293 Cells', 'Hedgehog Proteins', 'Human... | 25,369,031 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.543.990.150'], ['B01.050'], ['D12.776.091'], ['D12.776.094'], ['D12.776.157'], ['D12.776.167'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['G05.308.310'], ['A11.251.210.172.750', 'A11.436.334'], ['D12.644.276.671', 'D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A controlled study of early neurologic abnormalities in men with asymptomatic human immunodeficiency virus infection. | BACKGROUND: Although neurologic complications are frequent in the acquired immunodeficiency syndrome, their incidence and progression in early human immunodeficiency virus (HIV) infection remain controversial. The goal of this study was to assess neurologic manifestations in asymptomatic carriers of HIV.METHODS: We stu... | ['Adult', 'Audiometry', 'CD4-Positive T-Lymphocytes', 'Electroencephalography', 'Electronystagmography', 'Evoked Potentials, Somatosensory', 'Evoked Potentials, Visual', 'HIV Infections', 'HIV Seropositivity', 'Homosexuality', 'Humans', 'Leukocyte Count', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Nervous Sy... | 1,975,637 | [['M01.060.116'], ['E01.370.382.375.060'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.380.230.280', 'E01.370.382.900.280', 'E01.370.405.245.787.280', 'E01.370.405.260'], ['G07.265.216.500.400', 'G11.561.200.500.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhanced production of succinic acid by overexpression of phosphoenolpyruvate carboxylase in Escherichia coli. | Fermentative production of succinic acid from glucose by Escherichia coli was significantly increased by overexpression of phosphoenolpyruvate carboxylase. In contrast, overexpression of phosphoenolpyruvate carboxykinase had no effect. Under optimized conditions, induction of the carboxylase resulted in a 3.5-fold incr... | ['Escherichia coli', 'Gene Transfer Techniques', 'Phosphoenolpyruvate Carboxylase', 'Succinates', 'Succinic Acid'] | 8,633,880 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.393.350'], ['D08.811.520.224.125.650'], ['D02.241.081.337.759'], ['D02.241.081.337.759.625']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Back pain in children: symptoms which should be taken seriously]. | Back pain in children is a rare but serious problem. The varied etiologies and the necessary diagnostic workup are illustrated in 8 children. Infectious processes were found in 3 children, spondylodiscitis twice and epidural abscess once. Tumours (one eosinophilic granuloma and one spinal ependymoma) were present in 2 ... | ['Adolescent', 'Algorithms', 'Back Pain', 'Child', 'Diagnosis, Differential', 'Diagnostic Imaging', 'Discitis', 'Female', 'Humans', 'Intervertebral Disc Displacement', 'Male', 'Spinal Cord Neoplasms', 'Spinal Diseases', 'Spondylitis', 'Spondylolysis'] | 8,765,378 | [['M01.060.057'], ['G17.035', 'L01.224.050'], ['C23.888.592.612.107'], ['M01.060.406'], ['E01.171'], ['E01.370.350'], ['C01.160.762.301', 'C05.116.165.762.301', 'C05.116.900.853.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['C04.588.614.250.803', 'C10.228.854.765', 'C1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Molecular field analysis of trophic relationships in soil-dwelling invertebrates to identify mercury, lead and cadmium transmission through forest ecosystems. | Contamination pathways in complex food chains in soil ecosystems can be difficult to elucidate. Molecular analysis of predator gut content can, however, rapidly reveal previously unidentified trophic interactions between invertebrates and thereby uncover pathways of pollutant spread. Here, we measured concentrations of... | ['Animals', 'Cadmium', 'Coleoptera', 'Croatia', 'Food Chain', 'Invertebrates', 'Lead', 'Mercury', 'Predatory Behavior', 'Seasons', 'Sequence Analysis, DNA', 'Soil', 'Soil Pollutants', 'Wales'] | 24,138,157 | [['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['B01.050.500.131.617.720.500.500.375'], ['Z01.542.248.295'], ['G16.500.275.157.250', 'N06.230.124.250'], ['B01.050.500'], ['D01.268.556.435', 'D01.552.544.435'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['F01.145.113.111.600', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Sjogren's syndrome presenting as remitting seronegative symmetric synovitis with pitting edema (RS3PE). | Remitting seronegative symmetric synovitis with pitting edema (RS3PE) syndrome is characterized by symmetrical and acute synovitis, pitting edema, the absence of rheumatoid factor, increased acute phase reactants, lack of bony erosions on radiography, and benign and short clinical course. Half of all patients with Sjog... | ['Adult', 'Antibodies, Antinuclear', 'Arthritis', 'Biopsy', 'Blood Sedimentation', 'Diagnosis, Differential', 'Edema', 'Female', 'Humans', 'Lymphocytes', 'Prednisolone', 'Rheumatoid Factor', 'Salivary Glands', "Sjogren's Syndrome", 'Syndrome', 'Synovitis'] | 12,923,344 | [['M01.060.116'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['C05.550.114'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.225.625.125', 'E05.200.62... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Initial blood pH during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: a multicenter observational registry-based study. | BACKGROUND: When an out-of-hospital cardiac arrest (OHCA) patient receives cardiopulmonary resuscitation (CPR) in the emergency department (ED), blood laboratory test results can be obtained by using point-of-care testing during CPR. In the present study, the relationship between blood laboratory test results during CP... | ['Aged', 'Blood Gas Analysis', 'Cardiopulmonary Resuscitation', 'Emergency Service, Hospital', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Middle Aged', 'Out-of-Hospital Cardiac Arrest', 'Point-of-Care Testing', 'Prospective Studies', 'Registries', 'Retrospective Studies', 'Statistics, Nonparametric', 'S... | 29,268,775 | [['M01.060.116.100'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E02.365.647.110'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['M01.060.116.630'], ['C14.280.383.610'], ['N04.590.874.500'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High-resolution nuclear magnetic resonance imaging and single photon emission computerized tomography--cerebral blood flow in a case of pure sensory stroke and mild dementia owing to subcortical arteriosclerotic encephalopathy (Binswanger's disease). | Pure sensory stroke (PSS) is typically caused by a lacunar infarct located in the ventral-posterior (VP) thalamic nucleus contralateral to the paresthetic symptoms. The lesion is usually so small that it cannot be seen on computerized tomography (CT), as illustrated by our case. In our moderately hypertensive, 72-year-... | ['Aged', 'Brain', 'Brain Diseases', 'Cerebrovascular Circulation', 'Cerebrovascular Disorders', 'Dementia', 'Humans', 'Intracranial Arteriosclerosis', 'Magnetic Resonance Imaging', 'Male', 'Organometallic Compounds', 'Oximes', 'Syndrome', 'Technetium', 'Technetium Tc 99m Exametazime', 'Tomography, Emission-Computed', '... | 3,502,532 | [['M01.060.116.100'], ['A08.186.211'], ['C10.228.140'], ['G09.330.100.159'], ['C10.228.140.300', 'C14.907.253'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.800', 'C14.907.137.126.372', 'C14.907.253.560.350'], ['E01.370.350.825.500'], ['D02.691'], ['D02.092... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of ultraprotective ventilation, extracorporeal carbon dioxide removal, and spontaneous breathing on lung morphofunction and inflammation in experimental severe acute respiratory distress syndrome. | BACKGROUND: To investigate the role of ultraprotective mechanical ventilation (UP-MV) and extracorporeal carbon dioxide removal with and without spontaneous breathing (SB) to improve respiratory function and lung protection in experimental severe acute respiratory distress syndrome.METHODS: Severe acute respiratory dis... | ['Animals', 'Carbon Dioxide', 'Extracorporeal Membrane Oxygenation', 'Lung', 'Prospective Studies', 'Random Allocation', 'Respiration, Artificial', 'Respiratory Distress Syndrome', 'Respiratory Mechanics', 'Swine', 'Treatment Outcome'] | 25,371,037 | [['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E02.880.301', 'E04.292.451'], ['A04.411'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E02.041.625', 'E02.365.647.729'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transduction of linked chromosomal genes between Pseudomonas aeruginosa strains during incubation in situ in a freshwater habitat. | Both transduction of single chromosomal loci and cotransduction of closely linked loci were observed between lysogenic and nonlysogenic strains of Pseudomonas aeruginosa in a freshwater habitat. Transductants were recovered at frequencies of 10(-6) to 10(-5) transductants per CFU. Transductants of lysogenized strains w... | ['Alleles', 'Bacteriophages', 'Chromosomes, Bacterial', 'DNA, Bacterial', 'Fresh Water', 'Genetic Linkage', 'Genetic Markers', 'Lysogeny', 'Plasmids', 'Pseudomonas aeruginosa', 'Transduction, Genetic', 'Virion', 'Water Microbiology'] | 2,106,824 | [['G05.360.340.024.340.030'], ['B04.123'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['D13.444.308.212'], ['G16.500.275.280', 'N06.230.232'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['G05.935.500', 'G06.920.877.500'], ['G05.360.600'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['E05.393.3... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Personality and the collective: bold homing pigeons occupy higher leadership ranks in flocks. | While collective movement is ecologically widespread and conveys numerous benefits on individuals, it also poses a coordination problem: who controls the group's movements? The role that animal 'personalities' play in this question has recently become a focus of research interest. Although many animal groups have distr... | ['Animals', 'Columbidae', 'Homing Behavior', 'Personality', 'Social Dominance'] | 29,581,403 | [['B01.050'], ['B01.050.150.900.248.165.150'], ['F01.145.113.646'], ['F01.752'], ['F01.145.813.650']] | ['Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An efficient key-management scheme for hierarchical access control in e-medicine system. | In e-medicine system, the sharing of patients' medical histories scattered among medical institutions through the Internet is highly desirable. The most immediate cryptographic need certainly is an efficient key management method to solve dynamic access problems in a user hierarchy. In this paper, we propose a practica... | ['Access to Information', 'Computer Security', 'Humans', 'Internet', 'Medical Records Systems, Computerized', 'Software Design'] | 21,526,333 | [['I01.880.604.473.352.500.030', 'L01.143.024', 'L01.737.030'], ['L01.224.134', 'N04.452.910.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['L01... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
[The clinical significance of interferon-gamma and its receptor in patients with schistosomiasis]. | OBJECTIVE: To study the expression of interferon-gamma (IFN-gamma) and type I interferon-y receptor (IFN-gammaRI) in the chronic and advanced patients of schistosomiasis japonica, and to discuss its clinical relationship with hepatic fibrosis. Methods IFN-yR1 in the peripheral blood lymphocytes was detected by ELISA, a... | ['Adult', 'Aged', 'Aged, 80 and over', 'Collagen Type III', 'Collagen Type IV', 'Female', 'Humans', 'Hyaluronic Acid', 'Interferon-gamma', 'Laminin', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Receptors, Interferon', 'Schistosomiasis japonica'] | 15,830,877 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D05.750.078.280.300.300', 'D12.776.860.300.250.300.300'], ['D12.776.860.300.250.400.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.77... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bone mineral density, hip axis length and risk of hip fracture in men: results from the Cornwall Hip Fracture Study. | Bone mineral density (BMD) and hip axis length (HAL) are important determinants of fracture risk in women. There are, however, few data concerning their predictive risk in men. The aim of this study was to determine the relationship between BMD, HAL and the risk of hip fracture in men. A case-control design was used. C... | ['Aged', 'Aged, 80 and over', 'Anthropometry', 'Bone Density', 'Case-Control Studies', 'Femur', 'Hip Fractures', 'Hip Joint', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Osteoporosis', 'Risk Factors'] | 11,199,191 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['G11.427.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A02.835.232.043.150'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['A02.835.583.411'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Malignancy risk scoring of hydatidiform moles. | BACKGROUND: Several risk factors leading to malignant transformation of hydatidiform moles have been described previously. Many studies showed that prophylactic chemotherapy for high risk hydatidiform moles could significantly decrease the incidence of malignancy. Thus, it is essential to discover a breakthrough to det... | ['Adult', 'Case-Control Studies', 'Cell Transformation, Neoplastic', 'Choriocarcinoma', 'Female', 'Follow-Up Studies', 'Gestational Age', 'Humans', 'Hydatidiform Mole', 'Logistic Models', 'Neoplasm Grading', 'Pregnancy', 'Prognosis', 'Risk Factors', 'Uterine Neoplasms'] | 25,824,778 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C04.557.465.955.207', 'C04.557.470.200.025.455', 'C04.850.908.208', 'C13.703.720.949.208'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dexmedetomidine. | Dexmedetomidine is a potent alpha2-adrenoceptor agonist with 8 times higher affinity for the alpha2-adrenoceptor than clonidine. Dexmedetomidine has shown sedative, analgesic and anxiolytic effects after intravenous administration to healthy volunteers or postsurgical patients in the intensive care unit. Dexmedetomidin... | ['Adrenergic alpha-Agonists', 'Blood Pressure', 'Bradycardia', 'Dexmedetomidine', 'Heart Rate', 'Humans', 'Hypnotics and Sedatives', 'Hypotension', 'Infusions, Intravenous', 'Intensive Care Units', 'Nausea', 'Postoperative Care', 'Respiration, Artificial'] | 10,730,549 | [['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.067.319', 'C23.550.073.300'], ['D03.383.129.308.245'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Isolation and characterization of c-fos-expressing murine bone marrow stromal cell lines supporting myeloid differentiation. | We have previously reported that constitutive expression of c-fos oncogene allows long-term proliferation of primary mouse bone marrow stromal cells favoring the granulocytic differentiation of myeloid precursors in an in vitro assay. Retrovirus-mediated gene transfer of the human c-fos gene was used here for immortali... | ['Animals', 'Base Sequence', 'Bone Marrow', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Line', 'Cell Separation', 'Coculture Techniques', 'Cytokines', 'Gene Expression', 'Genes, fos', 'Granulocyte Colony-Stimulating Factor', 'Granulocytes', 'Hematopoietic Stem Cells', 'Humans', 'Mice', 'Molecular Sequence Data',... | 8,642,870 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251.210'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.481.500.374'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.297'], ['G05.360.340.024.340.37... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences. | Comparative approaches were used to identify human, mouse and rat dioxin response elements (DREs) in genomic sequences unambiguously assigned to a nucleotide RefSeq accession number. A total of 13 bona fide DREs, all including the substitution intolerant core sequence (GCGTG) and adjacent variable sequences, were used ... | ['Animals', 'Aryl Hydrocarbon Hydroxylases', 'Base Sequence', 'Computational Biology', 'Conserved Sequence', 'Cytochrome P-450 CYP1B1', 'Environmental Pollutants', 'Female', 'Gene Expression Profiling', 'Genomics', 'Humans', 'Liver', 'Mice', 'Mice, Inbred C57BL', 'Oligonucleotide Array Sequence Analysis', 'Polychlorina... | 15,328,365 | [['B01.050'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['H01.158.273.180', 'L01.313.124'], ['G02.111.570.580'], ['D08.244.453.005.500', 'D08.244.453.100.875', 'D08.811.682.690.708.170.010.500', 'D08.811.682.690.708.170.020.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
â-Sarcoglycan Deficiency Reduces Atherosclerotic Plaque Development in ApoE-Null Mice. | BACKGROUND: Smooth muscle cells are important for atherosclerotic plaque stability. Their proper ability to communicate with the extracellular matrix is crucial for maintaining the correct tissue integrity. In this study, we have investigated the role of â-sarcoglycan within the matrix-binding dystrophin-glycoprotein c... | ['AMP-Activated Protein Kinases', 'Adipocytes', 'Adipokines', 'Adipose Tissue', 'Animals', 'Aorta, Thoracic', 'Aortic Diseases', 'Apolipoproteins E', 'Atherosclerosis', 'Cytokines', 'Disease Models, Animal', 'Disease Progression', 'Dystrophin-Associated Protein Complex', 'Female', 'Genetic Predisposition to Disease', '... | 28,768,281 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['A11.329.114'], ['D06.472.699.042', 'D12.644.276.024', 'D12.644.548.011', 'D12.776.467.024', 'D23.529.024'], ['A10.165.114'], ['B01.050'], ['A07.015.114.056.372'], ['C14.907.109'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.50... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlates of a perceived need for mental health assistance and differences between those who do and do not seek help. | BACKGROUND: This study examined prevalence of perceived need for mental health assistance, characteristics of people with a perceived need, and how persons with a need who sought help were different from those who did not.METHODS: A national random phone survey (n = 1,394) was conducted in Israel, which included questi... | ['Adult', 'Age Distribution', 'Aged', 'Demography', 'Female', 'Health Care Surveys', 'Health Services Needs and Demand', 'Humans', 'Israel', 'Male', 'Mental Health Services', 'Middle Aged', 'Patient Acceptance of Health Care', 'Random Allocation', 'Sampling Studies', 'Sex Distribution', 'Statistics as Topic', 'Telephon... | 10,327,839 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
[Bladder replacement and cancer of the bladder]. | Urothelial tumours which infiltrate the vesical muscle or more superficial tumours which resist localised treatment (resection+/-BCG or mytomicin C) should be considered for excision. Excision is successful in female cystectomy and in male radical cystoprostatectomy. For local tumours of the bladder (<T3), this treatme... | ['Cystectomy', 'Humans', 'Urinary Bladder Neoplasms', 'Urinary Diversion'] | 19,963,183 | [['E04.950.774.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351.937.820.945', 'C13.351.968.829.707'], ['E04.950.774.852']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The outcome of patients treated with sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer. | BACKGROUND: The role of cytoreductive nephrectomy in metastatic clear cell renal cell carcinoma (ccRCC) is controversial.OBJECTIVE: To determine the outcome of patients with metastatic ccRCC who receive sunitinib prior to planned nephrectomy.DESIGN, SETTING, AND PARTICIPANTS: The study combined the data from two prospe... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Carcinoma, Renal Cell', 'Chemotherapy, Adjuvant', 'Clinical Trials, Phase II as Topic', 'Disease Progression', 'Disease-Free Survival', 'Drug Administration Schedule', 'Female', 'Humans', 'Indoles', 'Kaplan-Meier Estimate', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Neoadjuv... | 21,612,860 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E02.186.170', 'E02.319.170'], ['E05.318.372.250.250.210', 'N05.715.360.330.250.250.210', 'N06.850.520.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surgical treatment outcome of subdural empyema: A clinical study. | A retrospective study of 28 patients identified with subdural empyema (SE) at the Department of Neurosurgery between the years 1995 and 2005 was carried out. SE occurred in all patients following bacterial meningitis. The six most frequently encountered clinical features included: (1) fever in 22 (79%) patients; (2) di... | ['Anti-Bacterial Agents', 'Child, Preschool', 'Consciousness Disorders', 'Craniotomy', 'Drainage', 'Empyema, Subdural', 'Female', 'Fever', 'Humans', 'Infant', 'Male', 'Meningism', 'Meningitis, Bacterial', 'Papilledema', 'Paresis', 'Recurrence', 'Retrospective Studies', 'Seizures', 'Treatment Outcome'] | 16,902,341 | [['D27.505.954.122.085'], ['M01.060.406.448'], ['C10.597.606.358', 'C23.888.592.604.359', 'F01.700.315', 'F03.615.300'], ['E04.525.190'], ['E02.309', 'E04.237'], ['C01.207.709.300', 'C01.830.305.330', 'C10.228.228.709.300', 'C23.550.470.756.305.500'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cross-Sectional Analysis of the Association between Periodontitis and Cardiovascular Disease Using the Korean Genome and Epidemiology Study Data. | This cross-sectional study aimed to evaluate the association between periodontitis and cardiovascular disease (CVD) by reviewing and discussing the role of the oral microbiome in periodontitis and CVD. This prospective cohort study used epidemiological data from the Korean Genome and Epidemiology Study from 2004 to 201... | ['Adult', 'Aged', 'Cardiovascular Diseases', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Periodontitis', 'Prospective Studies', 'Republic of Korea', 'Risk Factors', 'Stroke'] | 32,698,486 | [['M01.060.116'], ['M01.060.116.100'], ['C14'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.714.533'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['Z01.252.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Physiological characterization of thermotolerant yeast for cellulosic ethanol production. | The conversion of lignocellulose into fermentable sugars is considered a promising alternative for increasing ethanol production. Higher fermentation yield has been achieved through the process of simultaneous saccharification and fermentation (SSF). In this study, a comparison was performed between the yeast species S... | ['Brazil', 'Cellulose', 'Drug Tolerance', 'Ethanol', 'Fermentation', 'Industrial Microbiology', 'Kluyveromyces', 'Saccharomyces cerevisiae'] | 24,535,257 | [['Z01.107.757.176'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['G07.690.773.992'], ['D02.033.375'], ['G02.111.158.249', 'G03.191.249'], ['H01.158.273.540.460', 'J01.897.120.460'], ['B01.300.107.795.536', 'B01.300.930.536'], ['B01.300.107.795.785.800', 'B01.300.930.705.6... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 |
[Acute surgical diseases in spinal injuries with spinal cord lesions]. | Authors analyse the group of 22 operated patients admitted to the Spinal Centre of the Traumatological Hospital Brno for instable spinal fracture with the transversal lesion of the spinal cord, in whom the acutely affected abdomen and acute surgical disease manifested. The anamnestic and clinic examination of the abdom... | ['Abdomen', 'Acute Disease', 'Adult', 'Female', 'Humans', 'Male', 'Spinal Fractures', 'Spinal Injuries'] | 9,478,114 | [['A01.923.047'], ['C23.550.291.125'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.117.500.500', 'C26.404.812'], ['C26.117.500']] | ['Anatomy [A]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A portable precision pumping system for chronic, programmed insulin infusion. | This paper provides some details of a new insulin delivery system which includes a reservoir, a pump and a power pack. The reservoir holds 50 ml and is coupled to a precision peristaltic pump whose delivery can be set to any one of 128 different mean flow rates from 0 to 80 microliter/min (+/- 1.6% over 10 months) usin... | ['Animals', 'Diabetes Mellitus', 'Dogs', 'Evaluation Studies as Topic', 'Infusions, Parenteral', 'Insulin'] | 672,822 | [['B01.050'], ['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.337', 'N05.715.360.335'], ['E02.319.267.510'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Correlation of human cytochrome P4502C substrate specificities with primary structure: warfarin as a probe. | The regio- and stereoselectivity of warfarin metabolism have been used to assess structure-function relationships of human P4502C subfamily members. Metabolism was investigated using a yeast cDNA expression system in which full length cDNAs for P4502C8, -2C9 (alleles Arg144 Tyr358 Ile359 Gly417 and Arg144 Tyr358 Leu359... | ['Alleles', 'Base Sequence', 'Cytochrome P-450 Enzyme System', 'Humans', 'Hydroxylation', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Recombinant Proteins', 'Stereoisomerism', 'Structure-Activity Relationship', 'Substrate Specificity', 'Warfarin'] | 8,429,826 | [['G05.360.340.024.340.030'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.385', 'G02.607.348', 'G03.425'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['D12.776.828'], ['G02.607... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of the sealing capabilities of Ketac-silver and extra high copper alloy amalgam when used as retrograde root canal filling. | Apical microleakage following reverse retrograde root filling with extra high copper amalgam alloy was compared with that following a silver-glass ionomer retrofilling. The root canals of 56 extracted, single-rooted anterior human teeth were instrumented and obturated with laterally condensed gutta-percha and zinc oxid... | ['Cermet Cements', 'Copper', 'Dental Amalgam', 'Dental Leakage', 'Humans', 'Observer Variation', 'Reproducibility of Results', 'Retrograde Obturation', 'Root Canal Filling Materials'] | 8,245,758 | [['D01.552.033.690.250', 'D25.058.520.250', 'D25.339.208.720.250', 'D25.339.291.402.120', 'J01.637.051.058.520.250', 'J01.637.051.339.208.720.250', 'J01.637.051.339.291.402.120'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D25.339.208.291', 'J01.637.051.339.208.291'], ['C07.793.221'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
PPARbeta/delta potentiates PPARgamma-stimulated adipocyte differentiation. | It is well established that peroxisome proliferator-activated receptor-gamma (PPARgamma) has a critical role in modulating adipocyte differentiation based on gain-of-function and loss-of-function experiments. However, recent gain-of-function experiments suggest that PPARbeta may also have a role in mediating adipocyte ... | ['Adipocytes', 'Animals', 'Blotting, Northern', 'Cell Differentiation', 'Cells, Cultured', 'Culture Media', 'Gene Deletion', 'Ligands', 'Lipid Metabolism', 'Mice', 'PPAR delta', 'PPAR gamma', 'PPAR-beta', 'RNA, Messenger', 'Stem Cells', 'Time Factors'] | 15,247,146 | [['A11.329.114'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G04.152'], ['A11.251'], ['D27.720.470.305', 'E07.206'], ['G05.365.590.762.320', 'G05.558.800.320'], ['D27.720.470.480'], ['G03.458'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.826.239.555'], ['D12.776.826.239.588'], ['D... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell culture systems as tools for studying age-related changes in skeletal muscle. | Two aspects of muscle cell phenotype that may be affected by aging are amenable to study in vitro: proliferative potential and ability to differentiate. These processes in primary myoblast cultures as well as in established myoblast cell lines will be examined, and the usefulness of these in vitro systems in addressing... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Animals', 'Cell Culture Techniques', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'Child', 'Child, Preschool', 'Gene Expression', 'Humans', 'Infant', 'Infant, Newborn', 'Mice', 'Middle Aged', 'Muscle Proteins', 'Muscle, Skeletal', 'Phenotype', 'Phosphopyruvate Hydratas... | 7,493,208 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['M01.060.406'], ['M01.060.406.448'], ['G05.297'], [... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison between bipolar pulsed radiofrequency and monopolar pulsed radiofrequency in chronic lumbosacral radicular pain: A randomized controlled trial. | BACKGROUND: Chronic lumbosacral radicular pain is a challenging medical problem with respect to therapeutic management. Many patients with lumbosacral radicular pain complain of persistent leg pain after transforaminal epidural steroid injection. Nowadays, pulsed radiofrequency (PRF) stimulation on the dorsal root gang... | ['Adult', 'Aged', 'Chronic Pain', 'Female', 'Ganglia, Spinal', 'Humans', 'Low Back Pain', 'Male', 'Middle Aged', 'Pulsed Radiofrequency Treatment'] | 28,248,888 | [['M01.060.116'], ['M01.060.116.100'], ['C23.888.592.612.274'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['M01.060.116.630'], ['E02.331.599', 'E02.779.468.599', 'E02.808.500', 'E02.831.535.468.599']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Organochlorine pesticide levels in blood serum samples taken at autopsy from auto accident victims in Veracruz, Mexico. | Samples of human blood sera (N = 118) for the determination of organochlorine pesticide levels were obtained at autopsy from auto accident victims in Veracruz, Mexico, during the years 2000 and 2001. The presence of hexachlorobenzene (HCH), beta-hexachlorocyclohexane (beta-HCH), 2,2-bis(p-chlorophenyl)-1,1-dichloroethy... | ['Accidents, Traffic', 'Adolescent', 'Adult', 'Aged', 'Female', 'Health Surveys', 'Humans', 'Hydrocarbons, Chlorinated', 'Male', 'Mexico', 'Middle Aged', 'Pesticides'] | 16,381,484 | [['N06.850.135.392'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.439'], ['Z01.107.567.589'], ['M01.060.116.630'], ['D27.720.031.700', 'D27.888.723']] | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Symptomatic Chiari malformations. An analysis of presentation, management, and long-term outcome. | The Chiari malformation is a condition characterized by herniation of the posterior fossa contents below the level of the foramen magnum, and is categorized into three types based on the degree of herniation. The authors review their surgical experience between 1975 and 1985 with 50 patients afflicted with symptomatic ... | ['Adolescent', 'Adult', 'Arnold-Chiari Malformation', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Prognosis', 'Time Factors'] | 2,746,341 | [['M01.060.057'], ['M01.060.116'], ['C10.500.680.291', 'C16.131.666.680.291'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['E01.789'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Time Warping Solutions for Classifying Artifacts in EEG. | The most common brain-computer interface (BCI) devices use electroencephalography (EEG). EEG signals are noisy owing to the presence of many artifacts, namely head movement, and facial movements like eye blinks or jaw movements. Removal of these artifacts from EEG signals is essential for the success of any downstream ... | ['Algorithms', 'Artifacts', 'Blinking', 'Electroencephalography', 'Humans', 'Signal Processing, Computer-Assisted'] | 31,946,874 | [['G17.035', 'L01.224.050'], ['E05.047'], ['G11.561.731.127', 'G14.152'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.800']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Immunohistochemical study of hemangioblastoma with special reference to its cytogenesis. | The cytogenesis of so-called hemangioblastoma arising in the central nervous system was investigated using the immunoreactivity to various proteins in cerebellar hemangioblastomas, extracerebellar hemangioblastomas, cerebral hemangiopericytomas, and hemangioendotheliomas, as well as a variety of meningiomas. The antise... | ['Adult', 'Aged', 'Brain', 'Diagnosis, Differential', 'Double-Blind Method', 'Female', 'Hemangioblastoma', 'Humans', 'Immune Sera', 'Immunohistochemistry', 'Male', 'Meningioma', 'Middle Aged', 'Stromal Cells'] | 7,692,317 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['E01.171'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C04.557.645.375.380.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', '... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Genetic and gender influences on sensitivity to focal cerebral ischemia in the stroke-prone spontaneously hypertensive rat. | We have investigated genetic transmission of increased sensitivity to focal cerebral ischemia and the influence of gender in the stroke-prone spontaneously hypertensive rat (SHRSP). Halothane-anesthetized, 3- to 5-month-old male and female Wistar-Kyoto rats (WKY), SHRSP, and the first filial generation rats (F1 crosses... | ['Animals', 'Brain Ischemia', 'Cerebrovascular Disorders', 'Female', 'Hypertension', 'Male', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Sex Factors'] | 10,024,327 | [['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300', 'C14.907.253'], ['C14.907.489'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.700.400.300'], ['B01.050.050.199.520.760.390', 'B01.050.150.900.649.313.992.635.505.700.400.390... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relationship of microbiological quality and oxidative stability of raw broiler meat during cold storage. | The purpose of this study was to determine whether 2-thiobarbituric acid (TBA) values could be used to predict microbiological spoilage of poultry meat. The TBA values of control and inoculated (cultured breast skin microflora, 10(5) cells/mL) chicken breast and leg meat were examined at 0, 2, 7, and 14 days storage in... | ['Animals', 'Bacteria', 'Chickens', 'Cold Temperature', 'Colony Count, Microbial', 'Food Microbiology', 'Food Preservation', 'Linear Models', 'Meat', 'Poultry', 'Thiobarbiturates'] | 2,813,253 | [['B01.050'], ['B03'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E01.370.225.875.220', 'E05.200.875.220'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Alternative barrier technique. | This article offers an alternative barrier technique that not only places the barrier in the dental treatment room, but also places it under the direct supervision and control of the dentist. A known hepatitis B carrier was selected for immediate denture treatment to illustrate and test this proposed barrier technique. | ['Aged', 'Dentists', 'Disinfection', 'Hepatitis B', 'Humans', 'Infection Control', 'Infectious Disease Transmission, Patient-to-Professional', 'Male', 'Universal Precautions'] | 8,242,167 | [['M01.060.116.100'], ['M01.526.485.330', 'N02.360.330'], ['N06.850.780.200.450.850.375'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.780.200.450'], ['N06.850.335.500'], ['N06.850.780.200.925']] | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genes, pathways and transcription factors involved in seedling stage chilling stress tolerance in indica rice through RNA-Seq analysis. | BACKGROUND: Rice plants show yellowing, stunting, withering, reduced tillering and utimately low productivity in susceptible varieties under low temperature stress. Comparative transcriptome analysis was performed to identify novel transcripts, gain new insights into different gene expression and pathways involved in c... | ['Cold-Shock Response', 'Energy Metabolism', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Genotype', 'Oryza', 'Photosynthesis', 'Plant Proteins', 'Sequence Analysis, RNA', 'Signal Transduction', 'Transcription Factors'] | 31,412,781 | [['G07.775.249'], ['G03.295'], ['E05.393.332'], ['G05.308.375'], ['G05.380'], ['B01.650.940.800.575.912.250.822.616'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['D12.776.765'], ['E05.393.760.710'], ['G02.111.820', 'G04.835'], ['D12.776.930']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunoreactive somatostatin in human pancreatic secretion. | Somatostatin in human pancreatic juice collected during endoscopic retrograde cholangiopancreatography following secretin injection was determined by RIA. The mean immunoreactive somatostatin (IRS) levels in the pancreatic juice of 13 non-diabetics was 78 +/- 11 (SE) pg/ml. The IRS levels in 4 non-insulin-dependent di... | ['Adult', 'Aged', 'Diabetes Mellitus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Juice', 'Secretin', 'Somatostatin'] | 6,109,735 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A12.200.567'], ['D06.472.317.800', 'D06.472.699.810', 'D12.644.400.705', 'D12.644.548.810', 'D12.776.631.650.705'], ['D06.472.699.327.700.875', 'D06.472.699.587.780', 'D12.644.4... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Appearance of bax protein after preoperative chemoradiotherapy is a prognostic factor in maxillary cancer. | The prognosis for maxillary squamous cell carcinoma (SCC) remains poor, despite advances in combination therapy. Combined treatment with anticancer drugs and radiation therapy is aimed at inducing apoptosis. As apoptosis is regulated by several proteins, we investigated the expression of p53, Bax and Bcl-2 in maxillary... | ['Antineoplastic Combined Chemotherapy Protocols', 'Combined Modality Therapy', 'Genes, p53', 'Humans', 'Immunohistochemistry', 'Maxillary Neoplasms', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Preoperative Care', 'Prognosis', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-bcl-2', 'bcl-2-Associated ... | 11,813,905 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The frequency of occurrence of acyclic monoterpene alcohols in the chemical environment does not determine olfactory sensitivity in nonhuman primates. | Using a conditioning paradigm, the olfactory sensitivity of five spider monkeys, three squirrel monkeys, and three pigtail macaques for six acyclic monoterpene alcohols that differ markedly in their frequency of occurrence in plant odors was assessed. The results showed that: (1) all three primate species have a well-d... | ['Alcohols', 'Animals', 'Cebidae', 'Macaca nemestrina', 'Monoterpenes', 'Odorants', 'Sensory Thresholds', 'Smell'] | 16,770,721 | [['D02.033'], ['B01.050'], ['B01.050.150.900.649.313.988.400.600.150'], ['B01.050.150.900.649.313.988.400.112.199.120.510.560'], ['D02.455.849.575'], ['G16.500.275.640', 'N06.230.480'], ['F02.463.593.710'], ['F02.830.816.643', 'G11.561.790.643']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A modified vertical muscle transposition for the treatment of large-angle esotropia due to sixth nerve palsy. | INTRODUCTION: Multiple different procedures have been proposed to address complete sixth nerve palsy with severe abduction limitation. In this study, we report a modification of the Hummelsheim's procedure. It is in fact muscle pulley transposition that obviates the need for tenotomy or muscle splitting. For the first ... | ['Abducens Nerve Diseases', 'Adult', 'Esotropia', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oculomotor Muscles', 'Ophthalmologic Surgical Procedures', 'Suture Techniques', 'Sutures', 'Tenotomy'] | 29,985,743 | [['C10.292.150'], ['M01.060.116'], ['C10.292.562.887.300', 'C11.590.810.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567.700'], ['E04.540'], ['E04.987.775'], ['E07.858.690.820'], ['E04.555.712']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Control of the annual testicular cycle of the marbled-newt by p53, p21, and Rb gene products. | p53, p21, and Rb are proteins with an important role in cell-cycle control. The expression and distribution of these gene products and the apoptotic rate were studied in the marbled-newt testis along the annual cycle to know the role of these factors in the control of spermatogenesis and glandular tissue formation. The... | ['Animals', 'Apoptosis', 'Blotting, Western', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclins', 'In Situ Nick-End Labeling', 'Male', 'Phosphorylation', 'Retinoblastoma Protein', 'Salamandridae', 'Testis', 'Time Factors', 'Tumor Suppressor Protein p53'] | 12,203,830 | [['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['D12.644.360.262', 'D12.776.167.218', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement of erythrocyte methotrexate polyglutamate levels: ready for clinical use in rheumatoid arthritis? | Methotrexate (MTX) is one of the most commonly prescribed and most effective drugs for the treatment of rheumatoid arthritis (RA). Given the partial response of many patients and the side effect profile of the drug, there is considerable interest in identifying biomarkers to guide MTX therapy in RA. Upon entering cells... | ['Arthritis, Rheumatoid', 'Dose-Response Relationship, Drug', 'Erythrocytes', 'Humans', 'Methotrexate', 'Polyglutamic Acid', 'Treatment Outcome'] | 20,665,136 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.733.631.192.500'], ['D12.125.067.625.700', 'D12.125.119.409.700', 'D12.644.748'], ['E01.789.800... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The glasgow prognostic score as a predictor of survival in patients with potentially resectable pancreatic adenocarcinoma. | BACKGROUND: Survival rates after resection of pancreatic adenocarcinoma are poor; however, several tumor-related prognostic factors have been identified. There is increasing evidence that additional patient-related prognostic factors, such as ongoing systemic inflammatory response, are associated with poor outcomes in ... | ['Adenocarcinoma', 'Aged', 'C-Reactive Protein', 'Female', 'Humans', 'Inflammation', 'Kaplan-Meier Estimate', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Neoplasm, Residual', 'Pancreatic Neoplasms', 'Pancreaticoduodenectomy', 'Prognosis', 'Proportional Hazards Models', 'Serum Albu... | 22,488,099 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', '... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
á7-Containing and non-á7-containing nicotinic receptors respond differently to spillover of acetylcholine. | We explored whether nicotinic acetylcholine receptors (nAChRs) might participate in paracrine transmission by asking if they respond to spillover of ACh at a model synapse in the chick ciliary ganglion, where ACh activates diffusely distributed á7- and á3-containing nAChRs (á7-nAChRs and á3*-nAChRs). Elevating quantal ... | ['Acetylcholine', 'Aconitine', 'Anesthetics, Local', 'Animals', 'Biophysical Phenomena', 'Cadmium Chloride', 'Calcium Channel Blockers', 'Chick Embryo', 'Cholinesterase Inhibitors', 'Conotoxins', 'Echothiophate Iodide', 'Excitatory Postsynaptic Potentials', 'Female', 'Ganglia, Parasympathetic', 'Lidocaine', 'Male', 'Mo... | 22,016,525 | [['D02.092.211.111'], ['D02.455.849.291.184.037', 'D03.132.301.030'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050'], ['G01.154'], ['D01.142.175', 'D01.210.450.150.125'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['A13.350.150', 'A16.331.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Typing and copy number determination for HLA-DRB3, -DRB4 and -DRB5 from next-generation sequencing data. | BACKGROUND: HLA-DRB3, DRB4 and DRB5 (DRB3/4/5) are paralogues of HLA-DRB1. They have important roles in transplantation and have been reported to be related to many diseases. HLA typing methods for DRB3/4/5 based on NGS data have many limitations now, such as need of polymerase chain reaction (PCR) or low accuracy.MATE... | ['Alleles', 'Chromosome Mapping', 'Continental Population Groups', 'Gene Dosage', 'Gene Expression', 'Gene Frequency', 'HLA-DRB3 Chains', 'HLA-DRB4 Chains', 'HLA-DRB5 Chains', 'Haplotypes', 'High-Throughput Nucleotide Sequencing', 'Histocompatibility Testing', 'Human Genome Project', 'Humans', 'Sequence Analysis, DNA'] | 28,145,101 | [['G05.360.340.024.340.030'], ['E05.393.183'], ['M01.686.508'], ['G05.380.350'], ['G05.297'], ['G05.330'], ['D12.776.395.550.509.400.440.200.030', 'D12.776.543.550.440.400.440.200.030', 'D23.050.301.500.400.400.440.200.030', 'D23.050.301.500.450.400.440.333.750', 'D23.050.705.552.410.400.440.200.030', 'D23.050.705.552.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Fecal markers of inflammation, protein loss, and microbial changes in dogs with the acute hemorrhagic diarrhea syndrome (AHDS). | BACKGROUND: Idiopathic acute hemorrhagic diarrhea syndrome (AHDS) is characterized by acute onset of bloody diarrhea, severe dehydration, and increased vascular and intestinal mucosal permeability. Markers of gastrointestinal inflammation, protein loss, and changes in the intestinal microbiota have not been studied ext... | ['Animals', 'Biomarkers', 'Diarrhea', 'Dog Diseases', 'Dogs', 'Feces', 'Gastrointestinal Hemorrhage'] | 28,771,910 | [['B01.050'], ['D23.101'], ['C23.888.821.214'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['A12.459'], ['C06.405.227', 'C23.550.414.788']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Features of myocardial infarction in chronic bronchitis patients]. | On the basis of a morphological examination of the heart and lungs at 337 autopsies of patients who had died of acute primary myocardial infarction, 108 cases were specified where myocardial infarction was related to a 3-10 year old history of chronic bronchitis. With regard to the bronchopulmonary system, autopsy find... | ['Adult', 'Bronchitis', 'Chronic Disease', 'Coronary Vessels', 'Female', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardium'] | 6,700,131 | [['M01.060.116'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['C23.550.291.500'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['A02.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mechanism of calcium accumulation in acetate-fed aerobic granule. | High calcium content has been widely reported in acetate-fed aerobic granules, but the reason behind this is unclear yet. By SEM-energy dispersive X-ray mapping analysis, this study showed that the majority of calcium was presented in the central part of the acetate-fed aerobic granule, and the granule shell part was n... | ['Acetates', 'Aerobiosis', 'Bioreactors', 'Biotechnology', 'Calcium', 'Electron Probe Microanalysis', 'Kinetics', 'Microscopy, Electron, Scanning', 'Models, Biological', 'Particle Size', 'Sewage', 'Waste Disposal, Fluid'] | 17,225,105 | [['D02.241.081.018', 'D10.251.400.045'], ['G02.111.017', 'G03.049'], ['E07.115', 'J01.897.120.115'], ['H01.158.550', 'J01.897.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['G01.374.661', 'G02.111.490'], ['E01.370.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Proteasome inhibitors reduce luciferase and beta-galactosidase activity in tissue culture cells. | Reporter enzymes are commonly used in cell biology to study transcriptional activity of genes. Recently, reporter enzymes in combination with compounds that inhibit proteasome function have been used to study the effect of blocking transcription factor degradation on gene activation. While investigating the effect of p... | ['Cysteine Endopeptidases', 'Cysteine Proteinase Inhibitors', 'Genes, Reporter', 'Luciferases', 'Multienzyme Complexes', 'Proteasome Endopeptidase Complex', 'Reverse Transcriptase Polymerase Chain Reaction', 'Tumor Cells, Cultured', 'beta-Galactosidase'] | 11,959,849 | [['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['D27.505.519.389.745.325'], ['G05.360.340.024.340.435'], ['D08.811.682.517', 'D12.776.532.510'], ['D05.500.562', 'D08.811.600'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['E05.393.620.500.725'], ['A11.251.860'], ['D08.811.277.450.410.100']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intracorporeal versus extracorporeal anastomosis after laparoscopic gastrectomy for gastric cancer. A systematic review with meta-analysis. | AIM: To perform a systematic review and meta-analyses of studies comparing the totally laparoscopic procedures with intracorporeal anastomosis (IA) to laparoscopic-assisted surgery with extracorporeal anastomosis (EA) in gastric resections.METHODS: We performed a systematic search in the electronic databases. Outcomes ... | ['Aged', 'Anastomosis, Surgical', 'Blood Loss, Surgical', 'Female', 'Gastrectomy', 'Humans', 'Laparoscopy', 'Length of Stay', 'Lymph Node Excision', 'Male', 'Margins of Excision', 'Middle Aged', 'Operative Time', 'Postoperative Hemorrhage', 'Prospective Studies', 'Publication Bias', 'Retrospective Studies', 'Stomach Ne... | 30,737,053 | [['M01.060.116.100'], ['E04.035'], ['C23.550.414.300', 'C23.550.505.300'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E04.446'], ['A10.830', 'C23.149.625'], ['M01.060.116.630'], ['E04.614.374.500', 'N02.421.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Negative priming from activation of counting and addition knowledge. | In two experiments, subjects were presented with digit pairs (e.g., 32) and asked to respond to the rightmost number. Negative priming, that is, slowed processing, was evident when the rightmost number was a counting-string (e.g., 43 following 12) or addition-sum (e.g., 65 following 32) associate of the number pair fro... | ['Affect', 'Association Learning', 'Cognition', 'Humans', 'Mental Recall', 'Paired-Associate Learning', 'Reaction Time', 'Semantics'] | 11,505,609 | [['F01.470.047'], ['F02.463.425.069.296'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.425.952.500'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['L01.559.598.745']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure. | OBJECTIVES: In this study, the anti-heart failure effect of icariin, a natural flavonol glycoside, and the underlying mechanisms were investigated.METHODS: Heart failure was induced by isoproterenol in male Sprague-Dawley rats. Matrix metalloproteinase activity was determined by gelatin zymography assay. The mRNA expre... | ['Angiotensin II', 'Animals', 'Apoptosis', 'Cardiotonic Agents', 'Disease Models, Animal', 'Down-Regulation', 'Flavonoids', 'Heart Failure', 'Hemodynamics', 'Isoproterenol', 'Male', 'Matrix Metalloproteinases', 'Mitochondria', 'Myocardium', 'Myocytes, Cardiac', 'Natriuretic Peptide, Brain', 'Norepinephrine', 'Rats', 'R... | 21,401,606 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['G04.146.954.035'], ['D27.505.954.411.222', 'D27.720.799.080'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selenium-associated DNA methylation modifications in placenta and neurobehavioral development of newborns: An epigenome-wide study of two U.S. birth cohorts. | BACKGROUND/AIM: Selenium (Se) levels in pregnancy have been linked to neurobehavioral development of the offspring. DNA methylation is a potential mechanism underlying the impacts of environmental exposures on fetal development; however, very few studies have been done elucidating the role of DNA methylation linking pr... | ['Child', 'Cohort Studies', 'DNA Methylation', 'Epigenesis, Genetic', 'Epigenome', 'Female', 'Humans', 'Infant Behavior', 'Infant, Newborn', 'Nervous System', 'New Hampshire', 'Placenta', 'Pregnancy', 'Selenium'] | 32,007,686 | [['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G05.308.203'], ['G05.360.340.006'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.179.500'], ['M01.060.703.520'], ['A08'], ['Z01.107.567.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Cancer screening for women is less frequently visited in regions with lower household income--analysis of data from health insurances in Bavaria]. | AIM OF THE STUDY: Differences in health care in Germany have rarely been analysed. Recent research, however, indicates that subjects of the lower social class participate in cancer screening less frequently.METHODS: Participation in screening for cervical cancer among women older than 20 years has been analysed using b... | ['Family Characteristics', 'Female', 'Germany', 'Humans', 'Income', 'Insurance, Health, Reimbursement', 'Mass Screening', 'Social Class', 'Uterine Cervical Neoplasms'] | 18,729,027 | [['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['N03.219.521.576.343.480', 'N03.219.521.710'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.3... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Effect of the HP0159 ORF mutation on the lipopolysaccharide structure and colonizing ability of Helicobacter pylori. | The outer core region of Helicobacter pylori lipopolysaccharide of the majority of isolates contains an alpha-1,6-glucan polymer synthesized by the product of the HP0159 ORF. Structural studies carried out on HP0159 lipopolysaccharide mutants by a combination of chemical methods, mass spectrometry and nuclear magnetic ... | ['Animals', 'Bacterial Proteins', 'Colony Count, Microbial', 'Gene Deletion', 'Helicobacter pylori', 'Lipopolysaccharides', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Mice', 'Mutagenesis, Insertional', 'Stomach', 'Virulence'] | 18,430,002 | [['B01.050'], ['D12.776.097'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G05.365.590.762.320', 'G05.558.800.320'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['E05.196.867.519'], ['E05.196.566'], ['B01.050.150.900.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection. | OBJECTIVES: Antiretroviral toxic neuropathy (ATN) is associated with dideoxynucleoside reverse transcriptase inhibitor use in patients infected with HIV, possibly as a result of mitochondrial toxicity. Acetyl-l-carnitine (ALC) has been linked to symptomatic improvement in ATN. We present an open-label single-arm pilot ... | ['AIDS-Related Opportunistic Infections', 'Acetylcarnitine', 'Confidence Intervals', 'DNA, Mitochondrial', 'Female', 'HIV-1', 'Humans', 'Male', 'Middle Aged', 'Nerve Fibers', 'Pain Measurement', 'Peripheral Nervous System Diseases', 'Pilot Projects', 'Reverse Transcriptase Inhibitors'] | 19,200,173 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['D02.092.877.883.099.090'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['D13.444.308.283.225'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of pre-treatment CYFRA 21 - 1 and SCC-Antigen assay in primary cervical carcinoma - a preliminary report. | CYFRA21 - 1, a fragment of cytokeratin19, has been widely assessed as a serum marker of squamous malignancies. Previous studies using CYFRA21 - 1 and SCC-Antigen have shown mixed results but have indicated a better predictive prognostic value for SCC-Ag as compared to CYFRA21-1. The aim of our prospective, observationa... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antigens, Neoplasm', 'Biomarkers, Tumor', 'Carcinoma, Adenosquamous', 'Carcinoma, Squamous Cell', 'Female', 'Humans', 'Keratin-19', 'Keratins', 'Lymphatic Metastasis', 'Middle Aged', 'Pilot Projects', 'Predictive Value of Tests', 'Prognosis', 'Prospective Studies', 'Serpins', 'Uteri... | 16,183,586 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['D23.050.285'], ['D23.101.140'], ['C04.557.435.250', 'C04.557.470.200.150'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450.300.900', 'D12.776.220.475.450.300.900', 'D12.776.860.607.3... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of maternal age on the incidence of obstetrical complications in Japan. | AIM: To clarify the effect of maternal age on obstetrical complications through a cohort and case-cohort study.METHODS: We studied 242 715 births at 125 centers of a perinatal network in Japan from 2001 through 2005 as a base cohort. Women with single pregnancies who delivered after 22 weeks of gestation were included ... | ['Abruptio Placentae', 'Adult', 'Case-Control Studies', 'Female', 'Humans', 'Hypertension, Pregnancy-Induced', 'Incidence', 'Japan', 'Maternal Age', 'Obstetric Labor Complications', 'Placenta Previa', 'Pregnancy', 'Pregnancy Outcome'] | 21,651,647 | [['C13.703.420.078', 'C13.703.590.132'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.395', 'C14.907.489.480'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Plasma esterase activity in patients with aspirin-sensitive asthma or urticaria. | Plasma aspirin esterase activity and cholinesterase activity were reduced in patients with aspirin sensitive asthma and aspirin sensitive urticaria compared to asthmatic and dermatological controls. Phenylacetate (non specific) esterase activities, were however unaltered in these patients. The reason for the lower acti... | ['Aspirin', 'Asthma', 'Butyrylcholinesterase', 'Cholinesterases', 'Esterases', 'Humans', 'Urticaria Pigmentosa'] | 3,443,144 | [['D02.455.426.559.389.657.410.595.176'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D08.811.277.352.100.170.250'], ['D08.811.277.352.100.170'], ['D08.811.277.352'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.565.465.500.850', 'C17.800.508.473.850', 'C17.800.621.893'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical assessment of subacromial shoulder impingement - Which factors differ from the asymptomatic population? | BACKGROUND: To date, the significance of factors purported to be associated with subacromial shoulder impingement (SSI) and what differences, if any, are present in those with SSI compared to a matched asymptomatic population has not been identified. Gaining information about differences between people with SSI and asy... | ['Biomechanical Phenomena', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychomotor Performance', 'Range of Motion, Articular', 'Rotation', 'Shoulder Impingement Syndrome', 'Shoulder Joint'] | 28,637,601 | [['G01.154.090', 'G01.374.089'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E01.370.600.700', 'G11.427.760'], ['G01.482.703'], ['C05.550.840', 'C26.803.500'], ['A02.835.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A perchlorate sensitive iodide transporter in frogs. | Nucleotide sequence comparisons have identified a gene product in the genome database of African clawed frogs (Xenopus laevis) as a probable member of the solute carrier family of membrane transporters. To confirm its identity as a putative iodide transporter, we examined the function of this sequence after heterologou... | ['Animals', 'COS Cells', 'Chlorocebus aethiops', 'Female', 'Gastric Mucosa', 'Iodine Radioisotopes', 'Kidney', 'Male', 'Membrane Transport Proteins', 'Perchlorates', 'Phylogeny', 'RNA, Messenger', 'Rana catesbeiana', 'Sodium', 'Symporters', 'Thyroid Gland', 'Transfection', 'Xenopus laevis'] | 18,275,962 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['A05.810.453'], ['D12.776.157.530', 'D12.776.543.585'], ['D01.029.260.650', 'D01.210.675'], [... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Congenital left ventricular wall abnormalities in adults detected by gated cardiac multidetector computed tomography: clefts, aneurysms, diverticula and terminology problems. | OBJECTIVES: Our aim was to evaluate congenital left ventricular wall abnormalities (clefts, aneurysms and diverticula), describe and illustrate imaging features, discuss terminology problems and determine their prevalence detected by cardiac CT in a single center.MATERIALS AND METHODS: Coronary CT angiography images of... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cardiac-Gated Imaging Techniques', 'Coronary Angiography', 'Female', 'Heart Defects, Congenital', 'Heart Ventricles', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Terminology as Topic', 'Tomography, X-Ray Computed', '... | 22,534,466 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.130.500'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.98... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Nebraska's rural behavioral healthcare workforce distribution and relationship between supply and county characteristics. | INTRODUCTION: Specific attention is needed to improve mental health outcomes in rural communities. Rural communities continue to have higher unmet mental health needs than their urban counterparts. Quantifying workforce supply and shortages can aid in identifying areas in need of the recruitment, training, licensure, a... | ['Counseling', 'Health Services Accessibility', 'Health Workforce', 'Humans', 'Mental Health Services', 'Nebraska', 'Needs Assessment', 'Psychiatry', 'Rural Health Services', 'Rural Population'] | 27,052,101 | [['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['N04.590.374.350', 'N05.300.430'], ['N02.350', 'N04.452.525.500', 'N05.300.420.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.408', 'N02.421.461'], ['Z01.107.567.875.510.520'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['F04.096... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
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