Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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CD95 (Fas) ligand-expressing vesicles display antibody-mediated, FcR-dependent enhancement of cytotoxicity. | Bioactive Fas ligand (FasL)-expressing vesicles were generated (vesicle preparation, VP) from two cell lines overexpressing FasL. The effect of NOK-1 anti-FasL mAb (mouse IgG1) on the cytotoxicity of FasL VP against various targets was determined. At high concentrations (1-10 microg/ml), NOK-1 inhibited the cytotoxicit... | ['Adjuvants, Immunologic', 'Animals', 'Antibodies, Blocking', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Antibody-Dependent Cell Cytotoxicity', 'Cell Line', 'Cell-Free System', 'Cytotoxicity Tests, Immunologic', 'Fas Ligand Protein', 'Humans', 'Immunoglobulin G', 'Immunoglobulin Isotypes', 'Immunosuppressive Ag... | 11,067,901 | [['D27.505.696.477.067'], ['B01.050'], ['D12.776.124.486.485.114.143', 'D12.776.124.790.651.114.143', 'D12.776.377.715.548.114.143'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['G12.287.070'], ['A11.251.210'], ['A11.284.835.168'], ['E01.370.225.812.160',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stimulus size dependence of hue changes induced by chromatic surrounds. | A chromatic surround induces a change in the perceived hue of a stimulus. This shift in hue depends on the chromatic difference between the stimulus and the surround. We investigated how chromatic induction varies with stimulus size and whether the size dependence depends on the surround hue. Subjects performed asymmet... | ['Adult', 'Color', 'Color Perception', 'Female', 'Humans', 'Male', 'Middle Aged', 'Photic Stimulation'] | 26,974,933 | [['M01.060.116'], ['G01.590.540.199'], ['F02.463.593.932.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.723.729']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Removal of unbound sodium dodecyl sulfate (SDS) from proteins in solution by electrophoresis through triton x-100-agarose. | Residual sodium dodecyl sulfate (SDS) introduces artifacts into immuno- and counterimmunoelectrophoretic analysis of proteins which have been eluted from preparative SDS-polyacrylamide gels. Unbound SDS can be removed by electrophoretic passage of eluted solutions through a barrier of Triton X-100 in agarose in which t... | ['Counterimmunoelectrophoresis', 'Erythrocytes', 'Glycoproteins', 'Immunoelectrophoresis', 'Polyethylene Glycols', 'Proteins', 'Sepharose', 'Sodium Dodecyl Sulfate'] | 621,409 | [['E01.370.225.812.735.645.350.350.150', 'E05.196.401.568.250', 'E05.200.812.735.645.350.350.150', 'E05.301.300.568.250', 'E05.478.594.760.645.350.350.150', 'E05.478.605.492.350.350.150'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D09.400.430', 'D12.776.395'], ['E01.370.225.812.735.645.350.350', 'E05.196.401... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Polyubiquitination events mediate polymethylmethacrylate (PMMA) particle activation of NF-kappaB pathway. | The pathologic response to implant wear-debris constitutes a major component of inflammatory osteolysis and remains under intense investigation. Polymethylmethacrylate (PMMA) particles, which are released during implant wear and loosening, constitute a major culprit by virtue of inducing inflammatory and osteolytic res... | ['Animals', 'Antimutagenic Agents', 'Disease Models, Animal', 'Extracellular Signal-Regulated MAP Kinases', 'I-kappa B Kinase', 'Inflammation', 'Intracellular Signaling Peptides and Proteins', 'MAP Kinase Kinase Kinases', 'Mice', 'Mice, Transgenic', 'NF-kappa B', 'Osteolysis', 'Polymethyl Methacrylate', 'TNF Receptor-A... | 21,566,132 | [['B01.050'], ['D27.505.696.706.080', 'D27.720.799.042'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['C23.550.470'], ['D12.644.360', 'D12.776.476'], ['D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Structural and functional alterations of neuromuscular junctions in NCAM-deficient mice. | The role of neural cell adhesion molecule (NCAM) in the development and maturation of the neuromuscular junction (NMJ) was explored by characterizing structurally and functionally NMJs from postnatal day 11 (P11) to P30 +/+, +/-, and -/- NCAM null mutant mice. Differences in NCAM levels resulted in alterations in the s... | ['Animals', 'Electric Stimulation', 'Heterozygote', 'In Vitro Techniques', 'Isometric Contraction', 'Membrane Potentials', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Motor Endplate', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Neural Cell Adhesion Molecules', 'Neuromuscular Junction', 'Neurons', 'Presynaptic ... | 10,964,958 | [['B01.050'], ['E05.723.402'], ['G05.380.383'], ['E05.481'], ['G11.427.494.472'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.31... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of the ORL1 receptor in the modulation of spinal neurotransmission by nociceptin/orphanin FQ and nocistatin. | Nociceptin/orphanin FQ and nocistatin are two neuropeptides with opposing effects on spinal neurotransmission and nociception. Nociceptin/orphanin FQ selectively suppresses excitatory glutamatergic neurotransmission, while nocistatin selectively interferes with glycinergic and gamma-aminobutyric acid (GABA)-ergic trans... | ['Analgesics, Opioid', 'Animals', 'Excitatory Postsynaptic Potentials', 'Female', 'Male', 'Opioid Peptides', 'Posterior Horn Cells', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Opioid', 'Vasodilator Agents'] | 11,166,734 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['D12.644.400.575', 'D12.776.631.650.575'], ['A08.186.854.697.500',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mycobacterium tuberculosis is the causative agent of tuberculosis in the southern ecological zones of Cameroon, as shown by genetic analysis. | BACKGROUND: Tuberculosis (TB) is a major cause of mortality and suffering worldwide, with over 95% of TB deaths occurring in low- and middle-income countries. In recent years, molecular typing methods have been widely used in epidemiological studies to aid the control of TB, but this usage has not been the case with ma... | ['Adolescent', 'Adult', 'Aged', 'Cameroon', 'Female', 'Humans', 'Male', 'Middle Aged', 'Minisatellite Repeats', 'Molecular Sequence Data', 'Mycobacterium tuberculosis', 'Phylogeny', 'Tuberculosis', 'Young Adult'] | 24,028,382 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.058.290.100.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G02.111.570.080.708.800.550', 'G05.360.080.708.800.550', 'G05.360.340.024.850.550'], ['L01.453.245.667'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Use of CAM in local African-American communities: community-partnered research. | Although previous national surveys have shown an increase in the use of complementary and alternative medicine (CAM) in the U.S. population, racial and ethnic minority populations were under-represented in these surveys. As a result, a profile of the CAM user as white, female, affluent, middle-aged and well educated ha... | ['African Americans', 'Attitude', 'Complementary Therapies', 'Focus Groups', 'Health Care Surveys', 'Humans', 'Patient Acceptance of Health Care', 'United States', 'Urban Population'] | 14,620,706 | [['M01.686.508.100.100', 'M01.686.754.100'], ['F01.100'], ['E02.190'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Changes in vitreous temperature during intravitreal surgery. | PURPOSE: To determine how different intraoperative surgical procedures affect the midvitreous temperature.METHODS: The vitreous temperatures were monitored continuously with an intravitreal thermocouple in 87 eyes of 81 cases undergoing vitrectomy. Thirty-three eyes had diabetic retinopathy (DR), 35 eyes had an epireti... | ['Adult', 'Aged', 'Aged, 80 and over', 'Body Temperature', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Intraoperative', 'Retinal Diseases', 'Retrospective Studies', 'Vitrectomy', 'Vitreous Body'] | 24,508,794 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.875.374', 'G07.110'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520.510', 'E04.510'], ['C11.768'], ['E05.318.372.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The region in the mu opioid receptor conferring selectivity for sufentanil over the delta receptor is different from that over the kappa receptor. | We determined the binding domains of sufentanil and lofentanil in the mu opioid receptor by comparing their binding affinities to seven mu/delta and six mu/kappa chimeric receptors with those to mu, delta and kappa opioid receptors. TMHs 6 and 7 and the e3 loop of the mu opioid receptor were important for selective bin... | ['Animals', 'Binding Sites', 'Binding, Competitive', 'CHO Cells', 'Cricetinae', 'Diprenorphine', 'Fentanyl', 'Kinetics', 'Protein Binding', 'Rats', 'Receptors, Opioid, delta', 'Receptors, Opioid, kappa', 'Receptors, Opioid, mu', 'Recombinant Fusion Proteins', 'Structure-Activity Relationship', 'Substrate Specificity', ... | 8,612,823 | [['B01.050'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['D03.132.577.249.250', 'D03.605.497.280', 'D03.633.400.686.275', 'D04.615.723.795.250'], ['D03.383.621.265'], ['G01.374.661', 'G02.111.490'], ['G02.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical activity and lung function-Cause or consequence? | Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies in smokers, is due to reverse causation. To investigate this, we applied structural equation modeling (SEM), an exploratory approach, and marginal structural modeling (M... | ['Adolescent', 'Adult', 'Asthma', 'Body Weight', 'Diet', 'Exercise', 'Female', 'Forced Expiratory Volume', 'Health Surveys', 'Humans', 'Longitudinal Studies', 'Lung', 'Male', 'Middle Aged', 'Respiratory Function Tests', 'Respiratory Tract Infections', 'Smokers', 'Smoking', 'Vital Capacity', 'Young Adult'] | 32,817,718 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.203.650.240'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.386.700.660.230', 'G09.772.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Detection and capture of breast cancer cells with photoacoustic flow cytometry. | According to the Centers for Disease Control and Prevention, breast cancer is the most common cancer and the second leading cause of cancer related deaths among women. Metastasis—the presence of secondary tumors caused by the spread of cancer cells via the circulatory or lymphatic systems—significantly worsens the prog... | ['Breast Neoplasms', 'Cell Separation', 'Flow Cytometry', 'Humans', 'Lasers', 'Neoplastic Cells, Circulating', 'Photoacoustic Techniques'] | 27,580,367 | [['C04.588.180', 'C17.800.090.500'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suboptimal bone status for adolescents with low motor competence and developmental coordination disorder-It's sex specific. | BACKGROUND: Australian adolescents with low motor competence (LMC) have higher fracture rates and poorer bone health compared to European normative data, but currently no normative data exists for Australians.AIMS: To examine whether there were bone health differences in Australian adolescents with LMC or Developmental... | ['Adolescent', 'Australia', 'Bone Density', 'Case-Control Studies', 'Child', 'Cortical Bone', 'Exercise', 'Female', 'Humans', 'Male', 'Motor Skills', 'Motor Skills Disorders', 'Muscle, Skeletal', 'Organ Size', 'Radius', 'Sex Factors', 'Stress, Mechanical', 'Tibia', 'Tomography, X-Ray Computed', 'Weight-Bearing'] | 30,119,956 | [['M01.060.057'], ['Z01.639.100', 'Z01.678.100.373'], ['G11.427.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['A10.165.265.521'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808.260'], ['F03.625.813'], ['A02.633.567... | ['Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Electrophoretic study of myosin isoforms in white muscles of some teleost fishes. | 1. White skeletal muscle myosin of four marine teleost fish species (cod, blue whiting, Norway haddock, and spotted wolf-fish) was analyzed by native, SDS-PAGE, and 2-dimensional electrophoresis. 2. Four types of native myosin were present in cod, blue whiting and Norway haddock. The second fastest migrating form was p... | ['Animals', 'Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Fishes', 'Muscles', 'Myosins', 'Species Specificity'] | 2,361,358 | [['B01.050'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.493'], ['A02.633', 'A10.690'], ['D05.750.078.730.475', 'D08.811.277.040.025.193.750', 'D12.776.210.500.600', 'D12.776.220.525.475'], ['G16.824']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clean intermittent self-catheterization: a 12-year followup. | We studied retrospectively 75 patients who performed clean intermittent self-catheterization for a mean of 7 years (maximum 12 years). Most of the patients had neuropathic bladder dysfunction and 92% were continent. Chronic or recurrent urinary tract infections were present in 42% of the patients. Although the upper ur... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Retrospective Studies', 'Self Care', 'Urethral Stricture', 'Urinary Bladder', 'Urinary Bladder, Neurogenic', 'Urinary Catheterization', 'Urinary Incontinence', 'Urinary Tract Infections'] | 2,329,604 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.5... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The phenotypic responses of human anterior cruciate ligament cells cultured on poly(epsilon-caprolactone) and chitosan. | The purpose of this study is to evaluate the phenotypic responses of human anterior cruciate ligament (ACL) cells on two biodegradable materials: poly(epsilon-caprolactone) (PCL) and chitosan. ACL cells cultured on PCL displayed phenotypes that were well spread with a developed cytoskeleton. In comparison, chitosan was... | ['Adult', 'Anterior Cruciate Ligament', 'Cell Adhesion', 'Cell Culture Techniques', 'Cell Proliferation', 'Chitosan', 'Cytoskeleton', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Integrins', 'Microscopy, Fluorescence', 'Polyesters', 'Tissue Engineering', 'Transforming Growth Factor beta1'] | 19,827,113 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['G04.022'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.161.750', 'G07.345.249.410.750'], ['D05.750.078.139.500', 'D09.698.211.500'], ['A11.284.430.214.190.750'], ['E05.478.566.350.170', 'E05.47... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Clinical retrospective analysis of long-pulsed 1064-nm Nd:YAG laser in the treatment of onychomycosis and its effect on the ultrastructure of fungus pathogen. | The objective of this study was to analyze retrospectively the clinical efficacy and fungal clearance of long-pulsed 1064-nm Nd:YAG laser for treating onychomycosis and explore the inhibitory effects of laser on the fungus pathogen-induced onychomycosis in vitro. We performed a systematic retrospective analysis of clin... | ['Adult', 'Colony Count, Microbial', 'Female', 'Humans', 'Lasers, Solid-State', 'Male', 'Onychomycosis', 'Retrospective Studies', 'Treatment Outcome', 'Trichophyton'] | 31,313,054 | [['M01.060.116'], ['E01.370.225.875.220', 'E05.200.875.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490.490', 'E07.710.520.490'], ['C01.150.703.302.720.550', 'C01.800.200.720.550', 'C17.800.529.550', 'C17.800.838.208.883.458'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma. | Loss of E-cadherin triggers peritoneal dissemination, leading to an adverse prognosis for most patients with epithelial ovarian carcinoma (EOC). Because TWIST mainly regulates the epithelial-to-mesenchymal transition and is one of the E-cadherin repressors, we investigated the possibility that TWIST expression affects ... | ['Adenocarcinoma', 'Adult', 'Aged', 'Biomarkers, Tumor', 'Cell Adhesion', 'Cell Line, Tumor', 'Cell Movement', 'Epithelial Cells', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Hyaluronan Receptors', 'Integrin beta1', 'Intercellular Adhesion Molecule-1', 'Matrix Metalloproteinase 14', 'Matrix Metallopr... | 17,487,558 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['G04.022'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['A11.436'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.735.200.625', 'D12.776.395.550.200.625.144', 'D12.776.395.650.750... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Which mini-mental state exam items can be used to screen for delirium and cognitive impairment? | Cognitive impairment is common in palliative care patients, but it is frequently undetected. The clinical consequence is that psychiatric states such as delirium, which often present with cognitive impairment, are inadequately treated. A short and simple questionnaire for screening of cognitive impairment is required f... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cognition Disorders', 'Delirium', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Mass Screening', 'Mental Status Schedule', 'Middle Aged', 'Norway', 'Psychometrics', 'Reproducibility of Results', 'Retrospective Studies', 'Sensitivity and Specificity', 'Surveys and Questi... | 16,043,006 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.615.250'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of manual compression release with distal pneumatic cuff maneuver in the ultrasonic evaluation of superficial venous insufficiency. | BACKGROUND: Venous reflux can be elicited either manually or by pneumatic tourniquet, and previous studies did not indicate any significant difference between these manoeuvres in patients with superficial venous insufficiency (SVI).PURPOSE: To investigate if two methods correlate in patients with CVI.MATERIALS AND METH... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Flow Velocity', 'Humans', 'Leg', 'Middle Aged', 'Pressure', 'Tourniquets', 'Ultrasonography, Doppler, Color', 'Venous Insufficiency'] | 16,750,921 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.370.130', 'G09.330.380.630.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['G01.374.715'], ['E07.926'], ['E01.370.350.850.850.850.850'], ['C14.907.952']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rupture of ectopic pregnancy in women with low and declining serum beta-human chorionic gonadotropin concentrations. | Rupture of tubal EP in two women whose serum beta-hCG levels were low and declining was reported. It suggests that low and falling serum beta-hCG levels are not always associated with resolution of EP and tubal rupture can still occur. | ['Adult', 'Chorionic Gonadotropin', 'Chorionic Gonadotropin, beta Subunit, Human', 'Female', 'Humans', 'Peptide Fragments', 'Pregnancy', 'Pregnancy, Ectopic', 'Rupture, Spontaneous'] | 1,717,319 | [['M01.060.116'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D06.472.699.322.326.125', 'D06.472.699.649.367.125', 'D12.644.548.726.367.125', 'D12.776.780.400.125', 'D23.101.140.325', 'D23.101.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541'], ['G08.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunophenotyping at the time of diagnosis distinguishes two groups of nasopharyngeal carcinoma patients: implications for adoptive immunotherapy. | BACKGROUND: Adoptive immunotherapy with EBV-specific CTLs (EBV-CTL) has been used to treat EBV-associated nasopharyngeal carcinoma (NPC) but only a fraction of the patients shows noticeable clinical response.PATIENTS AND METHODS: Sixty-seven newly diagnosed NPC patients from 2005 to 2007 and 21 healthy donors were coll... | ['Carcinoma', 'Cells, Cultured', 'Cytokines', 'Female', 'Herpesvirus 4, Human', 'Humans', 'Immunophenotyping', 'Immunotherapy, Adoptive', 'Leukocytes, Mononuclear', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Nasopharyngeal Neoplasms', 'T-Lymphocytes, Cytotoxic', 'Viral Matrix Proteins'] | 21,614,153 | [['C04.557.470.200'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['E02.095.465.425.400.330.050.400',... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Schistosoma mansoni antigens modulate the allergic response in a murine model of ovalbumin-induced airway inflammation. | Schistosoma mansoni infection has been associated with protection against allergies. The mechanisms underlying this association may involve regulatory cells and cytokines. We evaluated the immune response induced by the S. mansoni antigens Sm22.6, PIII and Sm29 in a murine model of ovalbumin (OVA)-induced airway inflam... | ['Alveolitis, Extrinsic Allergic', 'Animals', 'Antigens, Helminth', 'Asthma', 'Bronchoalveolar Lavage Fluid', 'CD4-Positive T-Lymphocytes', 'Cytokines', 'Disease Models, Animal', 'Female', 'Forkhead Transcription Factors', 'Immunization', 'Interleukins', 'Lung', 'Mice', 'Mice, Inbred BALB C', 'Ovalbumin', 'Pulmonary Eo... | 20,132,231 | [['C08.381.483.125', 'C08.674.055', 'C20.543.480.680.075'], ['B01.050'], ['D23.050.223'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.927.100.500'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.644.276.374', 'D12.776.467.374... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The degradation of airway tight junction protein under acidic conditions is probably mediated by transient receptor potential vanilloid 1 receptor. | Acidic airway microenvironment is one of the representative pathophysiological features of chronic inflammatory respiratory diseases. Epithelial barrier function is maintained by TJs (tight junctions), which act as the first physical barrier against the inhaled substances and pathogens of airway. As previous studies de... | ['Acidosis, Respiratory', 'Bronchi', 'Calcium Signaling', 'Cell Line', 'Cell Survival', 'Claudin-3', 'Claudin-4', 'Egtazic Acid', 'Electric Impedance', 'Humans', 'Hydrogen-Ion Concentration', 'Permeability', 'Proteolysis', 'Stress, Physiological', 'TRPV Cation Channels', 'Tight Junctions'] | 24,073,800 | [['C08.618.846.093', 'C18.452.076.176.310'], ['A04.411.125'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251.210'], ['G04.346'], ['D12.776.543.940.200.300'], ['D12.776.543.940.200.400'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['G01.358.500.249.277.350'], ['B01.050.150.900.649.313.... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RECORD processing - a robust pathway to component-resolved HR-PGSE NMR diffusometry. | It is demonstrated that very robust spectral component separation can be achieved through global least-squares CORE data analysis of automatically or manually selected spectral regions in complex NMR spectra in a high-resolution situation. This procedure (acronym RECORD) only takes a few seconds and quite significantly... | ['Algorithms', 'Diffusion', 'Electromagnetic Fields', 'Magnetic Resonance Spectroscopy', 'Signal Processing, Computer-Assisted', 'Software'] | 20,971,666 | [['G17.035', 'L01.224.050'], ['G01.202', 'G02.196'], ['G01.358.500.260', 'G01.358.750.500'], ['E05.196.867.519'], ['L01.224.800'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A novel mutation in CD83 results in the development of a unique population of CD4+ T cells. | Using a mouse mutagenesis screen, we have identified CD83 as being critical for the development of CD4(+) T cells and for their function postactivation. CD11c(+) dendritic cells develop and function normally in mice with a mutated CD83 gene but CD4(+) T cell development is substantially reduced. Additionally, we now sh... | ['Amino Acid Sequence', 'Animals', 'Antigens, CD', 'Base Sequence', 'CD4-Positive T-Lymphocytes', 'Cytokines', 'Dendritic Cells', 'Female', 'Immunoglobulins', 'Male', 'Membrane Glycoproteins', 'Mice', 'Molecular Sequence Data', 'Mutation', 'Pedigree'] | 15,322,158 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cationic, linear Au(I) N-heterocyclic carbene complexes: synthesis, structure and anti-mitochondrial activity. | Six linear, two-coordinate cationic Au(I) N-heterocyclic carbene complexes of the form [(R2Im)2Au]+ (R = Me 1, Me, Et 2, i-Pr 3, n-Bu 4, t-Bu 5 and Cy 6) have been prepared by the reaction of two equivalents of the appropriate dialkylimidazol-2-ylidene (R2Im) with (Me2S)AuCl in dmf. Single crystal structural studies fo... | ['Animals', 'Chemical Phenomena', 'Chemistry, Physical', 'Crystallography, X-Ray', 'Gold Compounds', 'Heterocyclic Compounds', 'In Vitro Techniques', 'Indicators and Reagents', 'Magnetic Resonance Spectroscopy', 'Mitochondria, Liver', 'Mitochondrial Membranes', 'Mitochondrial Swelling', 'Models, Molecular', 'Permeabili... | 16,865,184 | [['B01.050'], ['G02'], ['H01.181.529'], ['E05.196.309.742.225'], ['D01.379'], ['D03'], ['E05.481'], ['D27.720.470.410'], ['E05.196.867.519'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['A11.284.149.450.349', 'A11.284.835.514.349'], ['G04.590'], ['E05.599.595'], ['G02.723'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Significance of endostreptosin antibody titers in poststreptococcal glomerulonephritis. | Endostreptosin (ESS) is an immunologically well defined cytoplasmic antigen of group A and some group C streptococci. ESS is probably the pathogenetic antigen of poststreptococcal glomerulonephritis (ASGN). Antibodies to ESS (ESS-Ab) were determined by microcomplement fixation in 1,102 patients and by ELISA in 105 pati... | ['Adult', 'Antibodies, Bacterial', 'Antigens, Bacterial', 'Child', 'Complement Fixation Tests', 'Enzyme-Linked Immunosorbent Assay', 'Glomerulonephritis', 'Humans', 'Infant', 'Streptococcal Infections'] | 4,042,439 | [['M01.060.116'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['M01.060.406'], ['E01.370.225.812.735.150', 'E05.200.812.735.150', 'E05.478.594.760.150'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acute myeloid leukemia-FAB classification and its correlation with clinico-haematological features. | The French-American and British (FAB) classification of 62 consecutive cases of acute myeloid leukemia was undertaken. AML-M2 was the commonest FAB type (32.26%), followed by M1 and M4 (22.58% each), M5 (8.6%) and M6 and M7 (1.61% each), respectively. One of the patients was diagnosed as AML-MO (not a FAB type). The me... | ['Acute Disease', 'Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'France', 'Humans', 'Infant', 'Leukemia, Myeloid', 'Male', 'Middle Aged', 'Sex Factors', 'United Kingdom', 'United States'] | 8,114,248 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.557.337.539'], ['M01.060.116.630'], ['N05.715.350.6... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Molecular assessment of Plasmodium falciparum resistance to antimalarial drugs in China. | OBJECTIVE: In China, Chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) were abandoned for the treatment of falciparum malaria 20 years ago due to resistance. Subsequent field studies showed a trend of declining CQ and SP resistance in the country. The main purpose of this study was to analyse the molecular markers of... | ['Animals', 'Antimalarials', 'China', 'Chloroquine', 'Drug Resistance, Multiple', 'Humans', 'Malaria, Falciparum', 'Membrane Transport Proteins', 'Multidrug Resistance-Associated Proteins', 'Plasmodium falciparum', 'Point Mutation', 'Polymerase Chain Reaction', 'Protozoan Proteins', 'Sequence Analysis, DNA'] | 19,772,548 | [['B01.050'], ['D27.505.954.122.250.100.085'], ['Z01.252.474.164'], ['D03.633.100.810.050.180'], ['G07.690.773.984.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530.650', 'C01.920.875.650'], ['D12.776.157.530', 'D12.776.543.585'], ['D12.776.157.530.100.304', 'D12.776.157.530.450.074.500.500.500'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Tolerability of three selective cyclo-oxygenase-2 inhibitors, meloxicam, celecoxib and rofecoxib in NSAID-sensitive patients. | BACKGROUND: Patients with aspirin-sensitive respiratory and cutaneous diseases experience cross reactions to all nonsteroidal anti-inflammatory drugs (NSAIDs) which inhibit cyclo-oxigenase (COX) enzymes. As are now available drugs which selectively inhibit COX-2, questions are raised whether cross-reactivity occurs bet... | ['Adolescent', 'Adult', 'Aged', 'Angioedema', 'Anti-Inflammatory Agents, Non-Steroidal', 'Aspirin', 'Asthma', 'Celecoxib', 'Cross Reactions', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Cyclooxygenase Inhibitors', 'Drug Hypersensitivity', 'Female', 'Forced Expiratory Volume', 'Hemodynamics', 'Humans', 'Isoenzym... | 15,329,003 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14.907.079', 'C17.800.862.945.066', 'C20.543.480.904.066'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.426.559.389.657.410.595.176'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of combined DC and AC magnetic fields on germination of hornwort seeds. | Seeds of hornwort (Cryptotaenia japonica Hassk) were exposed to sinusoidally time-varying extremely low frequency (ELF) magnetic fields (AC fields) in combination with the local geomagnetic field (DC field). Exposure lasted 24 h/day for 16 days. Three directions of the AC magnetic fields were considered; the vertical (... | ['Electromagnetic Fields', 'Environmental Exposure', 'Germination', 'Humans', 'Light', 'Magnetics', 'Plants', 'Seeds', 'Temperature', 'Water'] | 15,376,241 | [['G01.358.500.260', 'G01.358.750.500'], ['N06.850.460.350'], ['G07.345.625.249', 'G15.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['H01.671.493'], ['B01.650'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['G01.906.595'... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Induction of immunologic tolerance in older New Zealand mice repopulated with young spleen, bone marrow, or thymus. | Newborn, 7-9 day, and 16-18 day old NZB and B/W mice were, unlike older New Zealand mice, rendered tolerant to single doses of 8-10 mg of soluble BGG. After challenge, this tolerance was of short duration and escape occurred rapidly. Age-matched and similarly treated C3H, Balb/c and C57Bl mice did not escape from toler... | ['Aging', 'Animals', 'Antibody Formation', 'Bone Marrow', 'Bone Marrow Cells', 'Bone Marrow Transplantation', 'Female', 'Hemagglutination', 'Immune Tolerance', 'Mice', 'Mycobacterium bovis', 'Radiation Effects', 'Spleen', 'Thymectomy', 'Thymus Gland', 'gamma-Globulins'] | 4,192,570 | [['G07.345.124'], ['B01.050'], ['G12.450.050.370.250'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G02.111.026.500', 'G12.122.100.200'], ['G12.535.425'], ['B01.050.150.900.649.313.992.635.505.500'], ['B03.510.024.962.500.402', 'B03.510.460.400.410.552.552.402'], ['G01.750... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Elevated [CO2] mitigates the effect of surface drought by stimulating root growth to access sub-soil water. | Through stimulation of root growth, increasing atmospheric CO2 concentration ([CO2]) may facilitate access of crops to sub-soil water, which could potentially prolong physiological activity in dryland environments, particularly because crops are more water use efficient under elevated [CO2] (e[CO2]). This study investi... | ['Atmosphere', 'Biomass', 'Carbon Dioxide', 'Dose-Response Relationship, Drug', 'Droughts', 'Plant Roots', 'Soil', 'Triticum', 'Water'] | 29,902,235 | [['G16.500.275.063', 'N06.230.300.100'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G07.690.773.875', 'G07.690.936.500'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['A18.400'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prolonged Evolution of Virus-Specific Memory T Cell Immunity after Severe Avian Influenza A (H7N9) Virus Infection. | Since 2013, influenza A H7N9 virus has emerged as the most common avian influenza virus subtype causing human infection, and it is associated with a high fatality risk. However, the characteristics of immune memory in patients who have recovered from H7N9 infection are not well understood. We assembled a cohort of 45 H... | ['Adult', 'Aged', 'Antibodies, Viral', 'CD8-Positive T-Lymphocytes', 'Female', 'Follow-Up Studies', 'Humans', 'Immunologic Memory', 'Influenza A Virus, H7N9 Subtype', 'Influenza, Human', 'Interferon-gamma', 'Male', 'Middle Aged', 'T-Lymphocyte Subsets', 'Time Factors'] | 29,925,664 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mold and Alternaria skin test reactivity and asthma in children in Connecticut. | BACKGROUND: Sensitivity to mold has been associated with asthma incidence, persistence, and severity.OBJECTIVE: To examine the relationship between skin test reactivity (STR) to molds and specifically to Alternaria and asthma severity in a group of ethnically diverse children in Connecticut.METHODS: Demographics and ST... | ['African Americans', 'Alternaria', 'Asthma', 'Connecticut', 'European Continental Ancestry Group', 'Female', 'Fungi', 'Hispanic Americans', 'Humans', 'Hypersensitivity', 'Incidence', 'Logistic Models', 'Male', 'Multivariate Analysis', 'Skin Tests', 'Spirometry'] | 21,457,878 | [['M01.686.508.100.100', 'M01.686.754.100'], ['B01.300.381.075'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['Z01.107.567.875.550.200'], ['M01.686.508.400'], ['B01.300'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['E05.318.308.985.525.375', 'N01.2... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Patterned PLG substrates for localized DNA delivery and directed neurite extension. | Tissue engineering strategies that enable nerve regeneration will require methods that can promote and direct neurite extension across the lesion. In this report, we investigate an in vitro combinatorial approach to directed neurite outgrowth using gene delivery from topographically patterned substrates, which can indu... | ['Animals', 'Cell Line', 'Chick Embryo', 'Coated Materials, Biocompatible', 'Coculture Techniques', 'DNA', 'Fluorescent Dyes', 'Gene Transfer Techniques', 'Humans', 'Materials Testing', 'Mice', 'Nerve Growth Factor', 'Neurites', 'Polyglactin 910', 'Surface Properties', 'Tissue Engineering'] | 17,324,456 | [['B01.050'], ['A11.251.210'], ['A13.350.150', 'A16.331.200'], ['D25.130.420', 'J01.637.051.130.420'], ['E05.481.500.374'], ['D13.444.308'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E05.393.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.6... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Detection on integron carried gene cassettes from pathogens by loop mediated isothermal amplification assays. | In this study, a number of frequently detected gene cassettes from bacterial integrons have been detected and characterized by rapid and simple loop-mediated isothermal amplification (LAMP) assays. Six gene cassettes commonly found in class 1 integrons were studied, including dfrA12, dfrA17, aadA2, aadA5, orfF, and bla... | ['Bacteria', 'DNA Primers', 'DNA, Bacterial', 'Genes, Bacterial', 'Hot Temperature', 'Integrons', 'Nucleic Acid Amplification Techniques', 'Sensitivity and Specificity'] | 28,392,412 | [['B03'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.212'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Examining Time Use of Dutch Nursing Staff in Long-Term Institutional Care: A Time-Motion Study. | OBJECTIVES: Increasing residents' acuity levels and available resources in long-term institutional care requires insight into the care provided by nursing staff so as to guide task allocation and optimal use of resources, and enhance quality of care. The purpose of this study was to examine the relationship between tim... | ['Cross-Sectional Studies', 'Female', 'Homes for the Aged', 'Humans', 'Male', 'Netherlands', 'Nursing Staff', 'Time and Motion Studies'] | 26,482,057 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.651'], ['M01.526.485.680', 'N02.360.680'], ['F02.784.412.846.707', 'F02.784.692.746.707']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Phase II study of a novel oral formation of 5-fluorouracil in combination with low-dose cisplatin as preoperative chemotherapy of oral squamous cell carcinoma. | TS-1 is a novel oral 5-fluorouracil containing tegaful (prodrug of 5-FU) and two biochemical modulators. These modulators feature effect-enhancing and adverse reaction-reducing activity. We investigated the histological response and toxicities of combination chemotherapy with TS- 1 and low-dose cisplatin and evaluated ... | ['Administration, Oral', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Squamous Cell', 'Cisplatin', 'Disease-Free Survival', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Drug Combinations', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mouth Ne... | 16,366,419 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.36... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Vitamin D status: effects on parathyroid hormone and 1, 25-dihydroxyvitamin D in postmenopausal women. | BACKGROUND: Low serum 25-hydroxyvitamin D ?25(OH)D concentrations are commonly found in the elderly and are associated with hip fracture. Treatment with vitamin D and calcium can reduce the risk of fracture. The relation between the rise in parathyroid hormone (PTH) with age and the decrease in 25(OH)D is not clear. Ne... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Bone and Bones', 'Calcifediol', 'Calcitriol', 'Calcium', 'Cross-Sectional Studies', 'Female', 'Humans', 'Linear Models', 'Middle Aged', 'Nutritional Status', 'Parathyroid Hormone', 'Postmenopause', 'Reference Values', 'Vitamin D'] | 10,837,301 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['A02.835.232', 'A10.165.265'], ['D04.210.500.247.222.159.478.250', 'D04.210.500.247.808.146.478.250', 'D04.210.500.812.768.196.478.250', 'D10.570.938.146.478.250'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comprehending Canadian police cautions: are the rights to silence and legal counsel understandable? | Comprehension of a Canadian police right to silence caution and a right to legal counsel caution was examined. Each caution was first presented verbally in its entirety, followed by its sentence-by-sentence presentation in written format. Participants (N = 56) were asked to indicate, after each presentation, their unde... | ['Adolescent', 'Adult', 'Canada', 'Civil Rights', 'Comprehension', 'Crime', 'Female', 'Humans', 'Lawyers', 'Male', 'Police', 'Reading', 'Self Disclosure', 'Sex Factors', 'Speech Perception', 'Young Adult'] | 19,882,632 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.567.176'], ['I01.880.604.473.352', 'N03.706.437.352'], ['F02.463.188.357'], ['I01.198.240', 'I01.880.735.191'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.520'], ['M01.526.373.750', 'M01.526.760'], ['L01.559.423.557'], ['F01.752.747.792.662'], ['N05.715.350.6... | ['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
An outbreak of introduced malaria in California possibly involving secondary transmission. | During 1974, 12 cases of Plasmodium vivax malaria were reported from an agricultural area in California's Sacramento Valley. At least three of these cases resulted from local mosquito transmission. The imported cases were in Punjabi immigrants except for one in an American-born visitor to the Punjab. This is the 11th r... | ['Adolescent', 'Adult', 'Anopheles', 'California', 'Child', 'Child, Preschool', 'Disease Outbreaks', 'Emigration and Immigration', 'Female', 'Humans', 'India', 'Insect Vectors', 'Malaria', 'Male', 'Middle Aged', 'Plasmodium vivax'] | 320,891 | [['M01.060.057'], ['M01.060.116'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.290'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Intracranial cerebrovascular vasa vasorum associated with atherosclerosis and large thick-walled aneurysms. | Atherosclerotic plaques that develop in the extracranial circulation are usually extensively vascularized by vasa vasorum. However, human vasa vasorum associated with intracranial atherosclerosis has not been adequately addressed. Anterior and posterior circulation specimens from fresh autopsy material were studied und... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Arteriosclerosis', 'Brain', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Intracranial Aneurysm', 'Intracranial Arteriosclerosis', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed', 'Vasa Vasorum'] | 1,745,961 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126'], ['A08.186.211'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['C10.228.140.300.510.800', 'C14.907.137.12... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteria. | To investigate the role of cytokines in interactions between lactic acid bacteria and the immune system, we measured production of tumor necrosis factor alpha, interleukin-6 (IL-6), and IL-10 from human peripheral blood mononuclear cells after stimulation with live or glutaraldehyde-fixed bacteria. Production of tumor ... | ['Actinomycetales Infections', 'Bifidobacterium', 'Cells, Cultured', 'Humans', 'Interleukin-10', 'Interleukin-6', 'Lactobacillus', 'Lactococcus', 'Leukocytes, Mononuclear', 'Tumor Necrosis Factor-alpha'] | 8,945,595 | [['C01.150.252.410.040'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['B03.353.750.450.475'... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evolution of the changes of the ileal pouch mucosa over a long follow-up period. | BACKGROUND/AIMS: The mucosa of the ileal pouch after restorative proctocolectomy develops relevant adaptative changes but the real mechanisms and the evolution over time of these alterations are still unclear. The aims of the present work were to study the distribution of the mucosal changes at different levels in the ... | ['Adult', 'Aged', 'Colonic Pouches', 'Female', 'Follow-Up Studies', 'Humans', 'Inflammation', 'Intestinal Mucosa', 'Male', 'Middle Aged', 'Time Factors'] | 14,571,740 | [['M01.060.116'], ['M01.060.116.100'], ['A10.850.200', 'E07.862.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['A03.556.124.369', 'A10.615.550.444'], ['M01.060.116.630'], ['G01.910.857']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
X-linked mental retardation syndrome with characteristic "coarse" facial appearance, brachydactyly, and short stature maps to proximal Xq. | We describe a three-generation family in which X-linked mental retardation (XLMR) is associated with minor facial anomalies and brachydactyly. Two brothers and four nephews have "coarse" facial appearance, brachydactyly with widening of the distal phalanges, short stature, and moderate mental retardation. The three obl... | ['Abnormalities, Multiple', 'Chromosome Mapping', 'DNA', 'Face', 'Family Health', 'Female', 'Genetic Linkage', 'Growth Disorders', 'Hand Deformities, Congenital', 'Humans', 'Intellectual Disability', 'Lod Score', 'Male', 'Microsatellite Repeats', 'Pedigree', 'Syndrome', 'X Chromosome'] | 10,398,234 | [['C16.131.077'], ['E05.393.183'], ['D13.444.308'], ['A01.456.505'], ['N01.400.300'], ['G05.348'], ['C23.550.393'], ['C05.390.408', 'C05.660.585.988.425', 'C16.131.621.585.988.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['G05.348.750'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Influence of Acoustic Overstimulation on the Central Auditory System: An Functional Magnetic Resonance Imaging (fMRI) Study. | BACKGROUND The goal of the fMRI experiment was to explore the involvement of central auditory structures in pathomechanisms of a behaviorally manifested auditory temporary threshold shift in humans. MATERIAL AND METHODS The material included 18 healthy volunteers with normal hearing. Subjects in the exposure group were... | ['Acoustic Stimulation', 'Acoustics', 'Adult', 'Auditory Cortex', 'Auditory Fatigue', 'Auditory Threshold', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Hearing Loss, Noise-Induced', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Noise', 'Young Adult'] | 27,893,698 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['H01.671.031'], ['M01.060.116'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['F02.463.593.071.173.095', 'G07.888.125.173.095'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['G07.265.216.500.370.300', 'G07.888.25... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Imported cutaneous leishmaniasis caused by Leishmania major in a Chinese laborer who worked in Saudi Arabia. | We report an imported case of cutaneous leishmaniasis in a 37-year-old man from Saudi Arabia caused by Leishmania major. He presented with non-healing nodulo-ulcerative lesions with a "volcanic crater" on the lower limbs. It was clearly cutaneous leishmaniasis - a rare disease in China - as reflected by the patient's c... | ['Adult', 'Antimony Sodium Gluconate', 'Antiprotozoal Agents', 'China', 'Emigrants and Immigrants', 'Humans', 'Leg Ulcer', 'Leishmania major', 'Leishmaniasis, Cutaneous', 'Male', 'Saudi Arabia'] | 27,438,208 | [['M01.060.116'], ['D02.125', 'D02.241.081.844.322.060', 'D02.241.511.902.322.060', 'D09.811.308.060'], ['D27.505.954.122.250.100'], ['Z01.252.474.164'], ['M01.189'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.893.592'], ['B01.268.475.868.488.405'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Bacteriologic studies in external otitis in Dar es Salaam, Tanzania. | The bacterial flora from the auditory canals of 54 patients (74 ears) with external otitis was studied. Pseudomonas aeruginosa was found in 38%. Aspergillus in 24%, Staphylococcus aureus in 18% and Candida albicans in 14%. Bacterial cultures from the auditory canals of 21 healthy subjects produced only the normal skin ... | ['Adult', 'Bacteria', 'Ear Canal', 'Female', 'Humans', 'Male', 'Mitosporic Fungi', 'Otitis Externa', 'Tanzania'] | 6,542,263 | [['M01.060.116'], ['B03'], ['A09.246.272.396'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.300.381'], ['C09.218.705.496'], ['Z01.058.290.120.840']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Intramolecular cross-linking experiments on cytochrome c and ribonuclease A using an isotope multiplet method. | Mass spectral analysis of tryptic digests of cross-linked proteins offers considerable promise as a simple technique to probe protein structure and study protein-protein interactions. We describe the use of a 1:1 mixture of isotopically labeled and unlabeled cross-linkers, disuccinimidyladipate (DSA) and dimethyladipim... | ['Cross-Linking Reagents', 'Cytochrome c Group', 'Hydrolysis', 'Indicators and Reagents', 'Models, Molecular', 'Myoglobin', 'Peptides', 'Protein Conformation', 'Ribonuclease, Pancreatic', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Trypsin'] | 11,803,535 | [['D27.720.470.410.210'], ['D08.244.286', 'D12.776.422.220.286'], ['G02.380'], ['D27.720.470.410'], ['E05.599.595'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['D12.644'], ['G02.111.570.820.709'], ['D08.811.277.352.355.350.715', 'D08.811.277.352.700.350.715'], ['E05.196.566.755'], ['D08.811.277.656.300.760.895', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Course of infection and case outcome in individuals diagnosed with microbial colonies morphologically consistent with Actinomyces species. | Actinomycosis is considered to be a rare disease in the oral region. A retrospective study of files of the University of Nebraska Medical Center College of Dentistry, Department of Pathology, revealed 30 cases in which Actinomyces species were detected from the years 1982 to 2001 (28,490 specimens). Biopsy submission f... | ['Actinomyces', 'Actinomycosis', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Biopsy', 'Curettage', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mandibular Diseases', 'Maxillary Diseases', 'Middle Aged', 'Nebraska', 'Periapical Diseases', 'Retrospective S... | 12,184,427 | [['B03.510.024.049.050.050', 'B03.510.460.400.400.049.049.178'], ['C01.150.252.410.040.137'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054'... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of 2 commercially available human chorionic gonadotropin immunoassays used in the management of gestational trophoblastic neoplasia. | OBJECTIVE: To compare serum human chorionic gonadotropin (hCG) titers using 2 commercially available hCG immunoassays in patients with gestational trophoblastic neoplasia (GTN).STUDY DESIGN: A total of 213 serum samples from 39 patients with uneventful moles and 697 serum samples from 17 patients with low-risk and high... | ['Chorionic Gonadotropin', 'Female', 'Gestational Trophoblastic Disease', 'Humans', 'Immunoassay', 'Pregnancy'] | 20,677,483 | [['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['C04.557.465.955.416', 'C04.850.908.416', 'C13.703.720.949.416'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['G08.686.784.769']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The next wave. In the new world of accountable, transparent care, CMIOs will be essential to organizational success. | As healthcare moves forward towards new, more accountable paradigms, CMIOs in patient care organizations nationwide are finding their positions becoming more and more focused on clinical transformation and process improvement. With such evolutionary changes are coming increased staff support, new reporting relationship... | ['Efficiency, Organizational', 'Hospital Administrators', 'Hospital Information Systems', 'Patient Care', 'Professional Role', 'Social Responsibility', 'Texas'] | 22,896,946 | [['N04.452.209.500'], ['M01.526.070.490.490', 'M01.526.485.430.490', 'M01.526.485.740.380', 'N02.360.430.490', 'N02.360.740.380'], ['N04.452.442.452.452', 'N04.452.515.360'], ['E02.760', 'N02.421.585'], ['F01.829.316.616.625'], ['F01.829.500.760', 'K01.752.566.869'], ['Z01.107.567.875.760.750']] | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The experience of physicians in pharmacogenomic clinical decision support within eight German university hospitals. | AIM: The aim of this study was to assess the physicians' attitude, their knowledge and their experience in pharmacogenomic clinical decision support in German hospitals.MATERIALS & METHODS: We conducted an online survey to address physicians of 13 different medical specialties across eight German university hospitals. ... | ['Adult', 'Aged', 'Attitude of Health Personnel', 'Decision Support Systems, Clinical', 'Female', 'Hospitals, University', 'Humans', 'Male', 'Middle Aged', 'Pharmacogenetics', 'Physicians', 'Surveys and Questionnaires', 'Young Adult'] | 28,593,816 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['L01.313.500.750.300.190'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H01.158.273.343.750', 'H01.158.703.052', 'H02.628.479'], ['M01.526.485.810', 'N02.360.810'], ['E05.3... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Rett females: patterns of characteristic side-asymmetric neuroimpairments at long-term follow-up. | From a follow-up series of 24 classical Rett syndrome females (13-59 years of age), side asymmetries of neuroimpairments were systematically investigated. A characteristic right-sided dominance in terms of dysfunction and neurology was revealed. Differences in the perinatal/early postnatal development of finer brain ne... | ['Adolescent', 'Adult', 'Female', 'Follow-Up Studies', 'Functional Laterality', 'Humans', 'Middle Aged', 'Neurologic Examination', 'Rett Syndrome'] | 12,571,789 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.376.550', 'E01.370.600.550'], ['C10.597.606.360.455.937', 'C16.320.322.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Single-stranded DNA gaps, tails and loops are repaired in Escherichia coli. | Uniformly methylated heteroduplex plasmids which contained 6 mismatched regions, including loops of 24, 30, 248 and 283 nucleotides, as well as single-stranded gaps and free ends were introduced into a recombination-deficient strain of bacteria, and the products of repair were analyzed. The results indicate that these ... | ['Base Composition', 'DNA Repair', 'DNA, Bacterial', 'DNA, Single-Stranded', 'Escherichia coli', 'Nucleic Acid Conformation', 'Nucleic Acid Heteroduplexes', 'Plasmids', 'Transformation, Genetic'] | 2,646,531 | [['G02.111.080'], ['G02.111.222', 'G05.219'], ['D13.444.308.212'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.500'], ['G05.360.600'], ['G05.728.865']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organ-specific autoantibodies in children with Helicobacter pylori infection. | BACKGROUND: We compared the prevalence of organ-specific autoantibodies in a group of Helicobacter pylori infected children and a group of uninfected children and investigated the relationship between the presence of relevant autoantibodies and the status of the target organs.PATIENTS AND METHODS: One hundred and twent... | ['Adolescent', 'Adult', 'Antigens, Bacterial', 'Autoantibodies', 'Bacterial Proteins', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Female', 'Gastroscopy', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Organ Specificity', 'Parietal Cells, Gastric'] | 15,610,075 | [['M01.060.057'], ['M01.060.116'], ['D23.050.161'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D12.776.097'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.372.250.250.325', 'E01.370.38... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cardiac and skeletal muscle enzyme levels in hypertensive and aging rats. | 1. The activities of glycolytic, fatty acid oxidation and citric acid cycle enzymes were measured in hypertensive and aging rat cardiac and skeletal muscles. 2. Lactate dehydrogenase and beta-hydroxyacyl-CoA dehydrogenase were significantly decreased in hypertensive, but not senescent, cardiac muscle. 3. Total phosphor... | ['3-Hydroxyacyl CoA Dehydrogenases', 'Aging', 'Animals', 'Calpain', 'Citrates', 'Citric Acid', 'Fatty Acids', 'Glycolysis', 'Hypertension', 'L-Lactate Dehydrogenase', 'Male', 'Muscles', 'Myocardium', 'Oxidation-Reduction', 'Phosphorylases', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY'] | 8,448,994 | [['D08.811.682.047.820.150'], ['G07.345.124'], ['B01.050'], ['D08.811.277.656.262.500.120', 'D08.811.277.656.300.200.120'], ['D02.241.081.901.434'], ['D02.241.081.901.434.249'], ['D10.251'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['C14.907.489'], ['D08.811.682.047.551.400', 'D08.811.682.047.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures. | Plasmids are mobile genetics elements that play an important role in the environmental adaptation of microorganisms. Although plasmids are usually analyzed in cultured microorganisms, there is a need for methods that allow for the analysis of pools of plasmids (plasmidomes) in environmental samples. To that end, severa... | ['Algorithms', 'Bacteria', 'Computational Biology', 'Genomics', 'Metagenome', 'Metagenomics', 'Phylogeny', 'Plasmids', 'Reproducibility of Results', 'Sequence Analysis, DNA'] | 29,346,586 | [['G17.035', 'L01.224.050'], ['B03'], ['H01.158.273.180', 'L01.313.124'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['G05.360.340.550'], ['H01.158.273.343.350.261'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.360.600'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Surgical treatment in acute occlusion of the large intestine caused by carcinoma]. | Fifty four cases of acute large bowel obstruction were observed in an overall groups of 266 patients with colonic carcinoma. Pre-operative elements which seems to contra-indicate a primary radical surgery and advantages of the same procedure are considered. In the experience of the Authors, primary and delayed staged r... | ['Acute Disease', 'Adenocarcinoma', 'Adult', 'Aged', 'Cecal Diseases', 'Colonic Diseases', 'Colonic Neoplasms', 'Female', 'Humans', 'Intestinal Obstruction', 'Male', 'Middle Aged', 'Palliative Care', 'Rectal Diseases', 'Sigmoid Diseases'] | 6,084,564 | [['C23.550.291.125'], ['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C06.405.469.110'], ['C06.405.469.158'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
New therapeutic vision of nutrition in dermatology: Integrative nutrition. | Many skin disorders have been associated with nutritional deficiencies, as well as many skin disorders, have been associated to diet-related immune mechanisms. The food can be a source of beneficial substances for health that act in very precise ways on the body and the functioning of each individual cells, tissues, an... | ['Delivery of Health Care, Integrated', 'Dermatology', 'Diet, Healthy', 'Humans', 'Nutrition Therapy', 'Nutritional Status', 'Nutritive Value', 'Recommended Dietary Allowances', 'Skin Diseases'] | 30,238,567 | [['N04.590.374.142', 'N05.300.262'], ['H02.403.225'], ['F01.829.458.205.500', 'G07.203.650.240.629'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.642'], ['G07.203.650.650', 'N01.224.425.525'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.850.601.750'], ['G07.203.650.620.500', 'I01.655.500.608.400.650.... | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Di... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
NS3 from Hepatitis C Virus Strain JFH-1 Is an Unusually Robust Helicase That Is Primed To Bind and Unwind Viral RNA. | Hepatitis C viruses (HCV) encode a helicase enzyme that is essential for viral replication and assembly (nonstructural protein 3 [NS3]). This helicase has become the focus of extensive basic research on the general helicase mechanism, and it is also of interest as a novel drug target. Despite the importance of this pro... | ['Cell Line', 'Crystallography, X-Ray', 'Genotype', 'Hepacivirus', 'Models, Molecular', 'Protein Binding', 'Protein Conformation', 'RNA, Viral', 'Viral Nonstructural Proteins', 'Virus Replication'] | 29,070,684 | [['A11.251.210'], ['E05.196.309.742.225'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['E05.599.595'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['D13.444.735.828'], ['D12.776.964.900'], ['G06.920.925']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Formation of DNA adducts in human buccal epithelial cells exposed to acetaldehyde and methylglyoxal in vitro. | Acetaldehyde (AA) and methylglyoxal (MG) are reactive, ubiquitous aldehydes, present in the environment and endogenously formed in animals and humans. They have both been shown to readily form DNA adducts under simulated physiological conditions. We report here on the use of cultured normal and SV40T antigen-immortaliz... | ['Acetaldehyde', 'Antigens, Polyomavirus Transforming', 'Cell Line, Transformed', 'Cells, Cultured', 'DNA Adducts', 'Dose-Response Relationship, Drug', 'Epithelial Cells', 'Humans', 'Mitochondria', 'Mouth Mucosa', 'Mutagens', 'Phosphorus Radioisotopes', 'Pyruvaldehyde', 'Succinate Dehydrogenase'] | 9,528,690 | [['D02.047.064'], ['D12.776.624.664.520.090', 'D12.776.964.700.090', 'D23.050.285.062.090', 'D23.050.327.062.090'], ['A11.251.210.172'], ['A11.251'], ['D13.444.308.135', 'G05.200.104'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.564', ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changing patterns of postoperative nausea and vomiting prophylaxis drug use in an academic anesthesia practice. | STUDY OBJECTIVE: To characterize the evolution of postoperative nausea and vomiting (PONV) prophylactic drug use.DESIGN: Retrospective data extraction and analysis of electronic anesthesia records.SETTING: Anesthesia department of an urban academic medical center.MEASUREMENTS: 144,134 anesthetics given by 57 attending ... | ['Adolescent', 'Antiemetics', 'Child', 'Dexamethasone', 'Droperidol', 'Female', 'Humans', 'Male', 'Metoclopramide', 'Ondansetron', 'Postoperative Nausea and Vomiting', 'Retrospective Studies'] | 17,869,986 | [['M01.060.057'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['M01.060.406'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D02.522.352.343', 'D03.633.100.103.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.277.573', 'D02.241.223.100.050.500.647', 'D02.241.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficient Synthesis of a Wide-Range Absorbing Azaphthalocyanine Dark Quencher and Its Application to Dual-Labeled Oligonucleotide Probes for Quantitative Real-Time Polymerase Chain Reactions. | Unsymmetrical dialkylamino-substituted zinc azaphthalocyanine (AzaPc) exhibits unique spectral and photophysical properties for dark quenchers of fluorescence in DNA hybridization probes. The panchromatic light absorption of AzaPc from 300 nm up to at least 700 nm and its lack of fluorescence make it an ideal candidate... | ['DNA Probes', 'Fluorescein', 'Fluorescent Dyes', 'Oligodeoxyribonucleotides', 'Oligonucleotide Probes', 'Real-Time Polymerase Chain Reaction'] | 29,683,215 | [['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D02.455.426.779.347.390', 'D03.633.300.953.275.390', 'D04.711.347.390'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D13.695.578.424.450'], ['D13.444.600.601', 'D27.505.259.750.600.650', 'D27.720.470.530.600.650'], ['E05.393.620.500.706... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinic and Home-Based Behavioral Intervention for Obesity in Preschoolers: A Randomized Trial. | OBJECTIVE: To test the hypotheses that an innovative skills-based behavioral family clinic and home-based intervention (LAUNCH) would reduce body mass index z score (BMIz) compared with motivational interviewing and to standard care in preschool-aged children with obesity.STUDY DESIGN: Randomized controlled trial with ... | ['Ambulatory Care', 'Behavior Therapy', 'Body Mass Index', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Home Care Services', 'Humans', 'Intention to Treat Analysis', 'Male', 'Motivational Interviewing', 'Pediatric Obesity', 'Single-Blind Method', 'Treatment Outcome'] | 29,150,147 | [['E02.760.106', 'N02.421.585.106'], ['F04.754.137'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.64... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serosorting and recreational drug use are risk factors for diagnosis of genital infection with chlamydia and gonorrhoea among HIV-positive men who have sex with men: results from a clinical cohort in Ontario, Canada. | OBJECTIVES: Rates of chlamydia and gonorrhoea have been rising in urban centres in Canada, particularly among HIV-positive men who have sex with men (MSM). Our objective was to identify behavioural risk factors for diagnosis with chlamydia and gonorrhoea in this population, with a focus on the HIV status of sexual part... | ['Chlamydia Infections', 'Gonorrhea', 'HIV Infections', 'HIV Serosorting', 'Homosexuality, Male', 'Humans', 'Illicit Drugs', 'Male', 'Ontario', 'Prevalence', 'Risk Factors', 'Substance-Related Disorders'] | 27,154,185 | [['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['C01.150.252.400.625.275', 'C01.150.252.734.401', 'C01.221.812.281.401', 'C01.778.281.401', 'C12.294.668.281.401', 'C13.351.500.711.281.401'], ['C01.221.250.875', 'C01.221.81... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Massive pulmonary embolism: surgical embolectomy versus thrombolytic therapy--should surgical indications be revisited? | OBJECTIVES: The treatment of massive pulmonary embolism (PE) is a matter of debate. We present our institutional experience of patients suffering from massive PE with the aim of comparing the early results, the outcome and quality of life (QoL) between patients primarily assigned to either pulmonary surgical embolectom... | ['Embolectomy', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Postoperative Complications', 'Pulmonary Embolism', 'Quality of Life', 'Retrospective Studies', 'Thrombolytic Therapy', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 22,466,693 | [['E04.100.814.445'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['C23.550.767'], ['C08.381.746', 'C14.907.355.350.700'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.372.500.500.500', 'E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Neurological presentations of oculodentodigital dysplasia]. | Oculodentodigital dysplasia (ODDD) is a rare autosomal dominant disorder caused by mutations in connexin 43 gene GJA1. Typical features are syndactyly of IV-V or III-V fingers with/without feet syndactyly, anomalies of eyes, teeth, hair and nose. In about 30% of patients neurological disorders appear later in life: pro... | ['Abnormalities, Multiple', 'Adolescent', 'Adult', 'Child', 'Craniofacial Abnormalities', 'Eye Abnormalities', 'Female', 'Foot Deformities, Congenital', 'Humans', 'Middle Aged', 'Mutation', 'Russia', 'Syndactyly', 'Tooth Abnormalities', 'Young Adult'] | 29,927,410 | [['C16.131.077'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C05.660.207', 'C16.131.621.207'], ['C11.250', 'C16.131.384'], ['C05.330.495', 'C05.660.585.512.380', 'C16.131.621.585.512.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.590'], ['Z01.252.122.500', 'Z01.542.248.... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The resting brain and our self: self-relatedness modulates resting state neural activity in cortical midline structures. | The resting brain shows high neural activity in various regions, the default-mode network, chief among them the cortical midline structures (CMS). The psychological correlate of high resting state neural activity in CMS remains however unclear though speculatively it has been associated with processing of internally-or... | ['Adult', 'Brain', 'Cerebral Cortex', 'Ego', 'Emotions', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Photic Stimulation', 'Prefrontal Cortex', 'Psychomotor Performance', 'Rest', 'Young Adult'] | 18,793,699 | [['M01.060.116'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['F01.752.747.189', 'F02.739.794.206'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['E05.723.729'], ['A08.186.211.200.885.287.500.270.700'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['I03.4... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Evaluation of the cytokine response in Kawasaki disease. | Intracellular cytokines interleukin 6, tumor necrosis factor (TNF) alpha and TNF-beta were studied in peripheral blood mononuclear cells of patients with Kawasaki disease during the acute, subacute and convalescent stages of the disease utilizing cytokine-specific monoclonal antibodies and indirect immunofluorescence. ... | ['Acute Disease', 'Antibodies, Monoclonal', 'Child', 'Child, Preschool', 'Female', 'Fluorescent Antibody Technique', 'Humans', 'Infant', 'Interleukin-6', 'Leukocytes, Mononuclear', 'Lymphotoxin-alpha', 'Male', 'Mucocutaneous Lymph Node Syndrome', 'Tumor Necrosis Factor-alpha', 'gamma-Globulins'] | 7,539,120 | [['C23.550.291.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.98... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
VH gene analysis of primary cutaneous B-cell lymphomas: evidence for ongoing somatic hypermutation and isotype switching. | Primary cutaneous B-cell lymphomas are B-cell non-Hodgkin's lymphomas that arise in the skin. The major subtypes discerned are follicle center cell lymphomas, immunocytomas (marginal zone B-cell lymphomas), and large B-cell lymphomas of the leg. In this study, we analyzed the variable heavy chain (VH) genes of 7 of the... | ['Codon', 'DNA, Neoplasm', 'Gene Rearrangement, B-Lymphocyte, Heavy Chain', 'Genes, Immunoglobulin', 'Immunoglobulin Class Switching', 'Immunoglobulin Heavy Chains', 'Immunoglobulin Variable Region', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymphoma, B-Cell', 'Lymphoma, Large B-Cell, Diffuse', 'Mutation', 'Neoplasm P... | 9,808,579 | [['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308.425'], ['G05.344.401.501', 'G12.500.274.501'], ['G05.360.340.024.340.335', 'G12.500.299'], ['G05.344.401.501.450', 'G12.500.274.501.450'], ['D12.776.124.486.485.705.500', 'D12.776.124.790.651.705.500', 'D12.776.377.715.548.705.500... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accuracy of mammography, digital breast tomosynthesis, ultrasound and MR imaging in preoperative assessment of breast cancer. | AIM: To define the accuracy of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to digital mammography (DM) and ultrasound (US) in the preoperative assessment of breast cancer.PATIENTS AND METHODS: We performed a prospective study of 200 consecutive women with histologically-proven breast c... | ['Adult', 'Aged', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Intraductal, Noninfiltrating', 'Carcinoma, Lobular', 'Female', 'Follow-Up Studies', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Mammography', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Pr... | 24,596,363 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Automated assay of ceruloplasmin by kinetic analysis of o-dianisidine oxidation. | Automated procedures for the kinetic assay of serum ceruloplasmin activity using a bichromatic and a centrifugal analyzer are described. The method is based on the oxidase activity of ceruloplasmin at pH 5.0 with o-dianisidine as substrate. Enzyme activity is reported in I.U./l, based on the molar absorption coefficien... | ['Autoanalysis', 'Ceruloplasmin', 'Dianisidine', 'Evaluation Studies as Topic', 'Humans', 'Indicators and Reagents', 'Kinetics', 'Methods', 'Oxidation-Reduction', 'Spectrophotometry'] | 1,277,556 | [['E05.059'], ['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12.776.157.160', 'D12.776.377.715.085.214', 'D12.776.556.151'], ['D02.455.426.559.389.185.220'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['G01.374.661', 'G02.111.490'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prognostic significance of Helix pomatia lectin and c-erbB-2 oncoprotein in human breast cancer. | We investigated the prognostic significance of Helix pomatia lectin (HPA) staining on disease-free and overall survival in 120 primary breast carcinomas. HPA staining was present in 58 (48%) of these carcinomas. It was significantly associated with axillary lymph node metastases (P < 0.001) and c-erbB-2 expression (P <... | ['Adult', 'Animals', 'Breast Neoplasms', 'Female', 'Helix, Snails', 'Hemagglutinins', 'Humans', 'Lectins', 'Lymphatic Metastasis', 'Middle Aged', 'Multivariate Analysis', 'Oncogene Proteins, Viral', 'Prognosis', 'Receptor, ErbB-2'] | 8,102,537 | [['M01.060.116'], ['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.500.644.400.750.450'], ['D27.505.696.477.136.377'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.503'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lung cancer mortality in a Dutch cohort of asphalt workers: evaluation of possible confounding by smoking. | BACKGROUND: Using data from a Dutch cohort of workers in road construction and asphalt mixing companies, this article describes possible confounding of the association between exposure to bitumen fume and lung cancer mortality by smoking.METHODS: A retrospective cohort of 3,714 workers with at least one season of emplo... | ['Adult', 'Cause of Death', 'Cohort Studies', 'Confounding Factors, Epidemiologic', 'Humans', 'Inhalation Exposure', 'Lung Neoplasms', 'Netherlands', 'Occupational Diseases', 'Occupational Exposure', 'Smoking'] | 12,494,424 | [['M01.060.116'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.240', 'N06.850.490.718'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.11... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The role of the epithelium in modulating the responses of guinea-pig trachea induced by bradykinin in vitro. | 1. The effect of removing the epithelium on the responses of the guinea-pig isolated trachea (GPT) to bradykinin (BK) and prostaglandin E2 (PGE2) was investigated. 2. BK (3 pmol-10 nmol) induced dose-related relaxations of the intact (with epithelium), and contracted the rubbed (without epithelium) preparation of GPT. ... | ['Acetylcholine', 'Adrenergic alpha-Antagonists', 'Adrenergic beta-Antagonists', 'Albuterol', 'Animals', 'Bradykinin', 'Dinoprostone', 'Epithelium', 'Epoprostenol', 'Guinea Pigs', 'Histamine Antagonists', 'In Vitro Techniques', 'Indomethacin', 'Male', 'Muscle Relaxation', 'Muscle, Smooth', 'Parasympatholytics', 'Radioi... | 1,972,894 | [['D02.092.211.111'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['B01.050'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Circulating tumour cells in patients with lung cancer undergoing endobronchial cryotherapy. | Early diagnosis of lung cancer still poses a major issue, with a large proportion of patients diagnosed at late stages. Therapeutic options and treatment remain limited in these patients. In most cases only palliative therapies are available to alleviate any severe symptoms. Endobronchial cryotherapy (EC) is one form o... | ['Aged', 'Airway Obstruction', 'Cell Count', 'Cryosurgery', 'Cryotherapy', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Neoplastic Cells, Circulating', 'Palliative Care', 'Pilot Projects', 'Prospective Studies'] | 26,043,899 | [['M01.060.116.100'], ['C08.618.846.185'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E04.014.180'], ['E02.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['A11.642', 'C04.697.650.900', 'C23.550.727.650.900'], ['E02.760.666', 'N... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Barriers and facilitators to implementing a regional anesthesia service in a low-income country: a qualitative study. | Introduction: Regional anesthesia is a safe alternative to general anesthesia. Despite benefits for perioperative morbidity and mortality, this technique is underutilized in low-resource settings. In response to an identified need, a regional anesthesia service was established at the University Teaching Hospital of Kig... | ['Anesthesia, Conduction', 'Developing Countries', 'Equipment Design', 'Health Personnel', 'Hospitals, University', 'Humans', 'Job Satisfaction', 'Poverty', 'Qualitative Research', 'Rwanda', 'Workload'] | 31,303,923 | [['E03.155.086'], ['I01.615.500.300'], ['E05.320'], ['M01.526.485', 'N02.360'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['H01.770.644.241.850'], ['Z01.058.290.120.680'], ['I03.946.225... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The wheat TabZIP2 transcription factor is activated by the nutrient starvation-responsive SnRK3/CIPK protein kinase. | KEY MESSAGE: The understanding of roles of bZIP factors in biological processes during plant development and under abiotic stresses requires the detailed mechanistic knowledge of behaviour of TFs. Basic leucine zipper (bZIP) transcription factors (TFs) play key roles in the regulation of grain development and plant res... | ['14-3-3 Proteins', 'Abscisic Acid', 'Amino Acid Sequence', 'Basic-Leucine Zipper Transcription Factors', 'Droughts', 'Gene Expression Regulation, Plant', 'Phylogeny', 'Plant Proteins', 'Plants, Genetically Modified', 'Promoter Regions, Genetic', 'Protein Binding', 'Protein Kinases', 'Seeds', 'Stress, Physiological', '... | 29,564,697 | [['D12.644.360.024.050', 'D12.776.157.057.002', 'D12.776.476.024.050'], ['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.260.108', 'D12.776.930.127'], ['G16.500.175.781',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Middle mesial canal of a mandibular first molar--a case report. | The mandibular first molar usually has only two mesial canals, a mesiolingual and a mesiobuccal. Cases of a third canal described as the middle mesial canal has been reported and is found to be uncommon. In this case report, three canals in the mesial root of a mandibular first molar were located, prepared and filled. ... | ['Adult', 'Humans', 'Male', 'Mandible', 'Molar', 'Tooth Root'] | 3,916,993 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['A14.549.167.860.525'], ['A14.549.167.900.750']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The development of a cisgenic apple plant. | Cisgenesis represents a step toward a new generation of GM crops. The lack of selectable genes (e.g. antibiotic or herbicide resistance) in the final product and the fact that the inserted gene(s) derive from organisms sexually compatible with the target crop should rise less environmental concerns and increase consume... | ['Malus', 'Plants, Genetically Modified'] | 21,663,775 | [['B01.650.940.800.575.912.250.859.937.500.444'], ['B01.650.520', 'B05.620.600']] | ['Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exploring the mechanism of F282L mutation-caused constitutive activity of GPCR by a computational study. | G-protein-coupled receptors (GPCRs) are important drug targets and generally activated by ligands. However, some experiments found that GPCRs also give rise to constitutive activity through some mutations (viz., CAM), which are usually associated with different kinds of diseases. However, the mechanisms of CAMs and the... | ['Amino Acid Motifs', 'Area Under Curve', 'Binding Sites', 'Hydrogen Bonding', 'Ligands', 'Molecular Dynamics Simulation', 'Mutagenesis, Site-Directed', 'Principal Component Analysis', 'Protein Stability', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', 'ROC Curve', 'Receptors, Adrenergic, beta-2'] | 27,735,961 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['G02.111.570.120'], ['G02.282'], ['D27.720.470.480'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['E05.393.420.601.575'], ['E05.318.740.562'], ['G02.111.700'], ... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Analysis of Gene Candidate SNP and Ancestral Origin Associated to Obesity and Postoperative Weight Loss in a Cohort of Obese Patients Undergoing RYGB. | INTRODUCTION: Obesity is the result of a complex interaction between multiple genetic traits and psychological, behavioral, nutritional and environmental factors.OBJECTIVES: The aims of the study were (a) to comparatively evaluate the presence of 20 candidate gene single nucleotide polymorphisms (SNPs) in morbidly obes... | ['Adolescent', 'Adult', 'Aged', 'Cohort Studies', 'Diabetes Mellitus, Type 2', 'Female', 'Gastric Bypass', 'Genetic Predisposition to Disease', 'Hispanic Americans', 'Humans', 'Male', 'Mexico', 'Middle Aged', 'Obesity, Morbid', 'Polymorphism, Single Nucleotide', 'Postoperative Period', 'Weight Loss', 'Young Adult'] | 28,035,522 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['C23.550.291.687.500', 'G05.380.355'], ['M01.686.754.441'], ['B01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Electrosurgery: advantages and disadvantages. | Though electrosurgery has been with us for decades, few surgeons have received formal training in its potential uses. The erroneous belief that electrosurgery techniques increase scar formation or impair healing processes, has led surgeons to other methods to deliver energy to the living cell. A watt, is a watt, is a w... | ['Carbon Dioxide', 'Electricity', 'Electrosurgery', 'Endometriosis', 'Female', 'Humans', 'Laser Therapy'] | 2,106,143 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G01.358.500.249'], ['E04.262'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanisms of tumor vascular shutdown induced by 5,6-dimethylxanthenone-4-acetic acid (DMXAA): Increased tumor vascular permeability. | The novel vascular targeting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) has completed phase 1 clinical trial and has shown tumor antivascular activity in both mice and humans. We have investigated its ability to change tumor vascular permeability, relating it to tumor vascular perfusion and other responses. The... | ['Adenocarcinoma', 'Animals', 'Antineoplastic Agents', 'Capillary Permeability', 'Colonic Neoplasms', 'Female', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Neoplasms, Experimental', 'Neovascularization, Pathologic', 'Receptors, Tumor Necrosis Factor, Type I', 'Tumor Cells, Cultured', 'Tumor Necrosis Factor... | 15,800,918 | [['C04.557.470.200.025'], ['B01.050'], ['D27.505.954.248'], ['G03.143.330', 'G09.330.165'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.1... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular forms of atrial natriuretic polypeptides circulating in human plasma. | Molecular forms of atrial natriuretic polypeptides circulating in human plasma were analyzed by chromatographic separation, coupled with radioimmunoassay. Analyses were done with human plasma samples taken from 24 human subjects, divided into groups of healthy volunteers, patients with renal disease, and patients with ... | ['Atrial Natriuretic Factor', 'Cross Reactions', 'Heart Diseases', 'Humans', 'Kidney Diseases', 'Molecular Weight'] | 2,949,746 | [['D06.472.699.584.500', 'D12.644.548.585.500'], ['G12.122.281'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['G02.494']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urban v. suburban perceptions of the neighbourhood food environment as correlates of adolescent food purchasing. | OBJECTIVE: To assess the relationship between adolescent perception of time to walk to neighbourhood food retail outlets and purchasing of sugar-sweetened beverages (SSB), fast and convenience food items, and to test for differences by urban v. suburban environment.DESIGN: Cross-sectional observational study.SETTING: T... | ['Adolescent', 'Adolescent Nutritional Physiological Phenomena', 'Beverages', 'Cluster Analysis', 'Commerce', 'Cross-Sectional Studies', 'Diet', 'Energy Intake', 'Fast Foods', 'Female', 'Humans', 'Male', 'Minnesota', 'Obesity', 'Perception', 'Statistics, Nonparametric', 'Time Factors', 'Urban Population', 'Walking'] | 21,859,510 | [['M01.060.057'], ['G07.203.650.220.060'], ['G07.203.100', 'J02.200'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['J01.219'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['G07.203.650.240.340'], ['G07.203.300.477', 'J02.500.477'], ['B01.05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Soci... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Presence of organochlorine pollutants in fat and scats of pinnipeds from the Antarctic Peninsula and South Shetland Islands, and their relationship to trophic position. | Antarctica is still considered one of the few pristine areas in the globe. Despite this, several studies have shown phased out organic pollutants are present in several environmental abiotic and biological compartments. This study, based on blubber and fecal samples collected from five species of Antarctic pinnipeds, a... | ['Animals', 'Antarctic Regions', 'Caniformia', 'Environmental Monitoring', 'Food Chain', 'Hydrocarbons, Chlorinated', 'Water Pollutants, Chemical'] | 31,272,787 | [['B01.050'], ['Z01.158'], ['B01.050.150.900.649.313.750.250'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.157.250', 'N06.230.124.250'], ['D02.455.526.439'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Dominance of functional androgen receptor allele with longer CAG repeat in hepatitis B virus-related female hepatocarcinogenesis. | The CAG polymorphism in exon 1 of the androgen receptor (AR) gene has been shown associated with the development of human male hepatocellular carcinoma (HCC) with the shorter AR alleles conferring a higher risk. However, the significance of AR-CAG repeats in female hepatocarcinogenesis remains to be addressed. In this ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Alleles', 'Allelic Imbalance', 'Carcinoma, Hepatocellular', 'DNA Methylation', 'Female', 'Hepatitis B', 'Hepatitis B virus', 'Humans', 'Liver Cirrhosis', 'Liver Neoplasms', 'Middle Aged', 'Receptors, Androgen', 'Repetitive Sequences, Nucleic Acid'] | 12,154,039 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G05.360.340.024.340.030'], ['G05.365.590.029'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['C01.221.250.500', 'C01.925.256.430.400', 'C0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ventilatory responses to hypocapnic vertebral artery perfusion in intact and carotid body denervated dogs. | The ventilatory responses to step changes in vertebral artery PCO2 were investigated in intact and carotid body denervated dogs. The steady-state ventilatory responses of the denervated dogs were less than those of intact dogs. However, when expressed as a ratio to the control ventilation there was no difference betwee... | ['Animals', 'Brain', 'Carbon Dioxide', 'Carotid Body', 'Dogs', 'Injections, Intra-Arterial', 'Regional Blood Flow', 'Respiration', 'Time Factors', 'Vertebral Artery'] | 6,792,675 | [['B01.050'], ['A08.186.211'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['A08.675.650.915.500.600.150', 'A08.800.950.500.600.150', 'A11.671.650.915.500.600.150'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.319.267.530.370'], ['G09.330.100.780'], ['G09.772.705'], ['G01.910.857'], ['A07.015.114.955']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular characterization and determination of antimicrobial resistance of Mycoplasma gallisepticum isolated from chickens. | In this study, three consecutive approaches of molecular characterization, determination of minimum inhibitory concentration (MIC) and antimicrobial tested on Mycoplasma gallisepticum (MG) isolated from chicken farms were investigated. These approaches were conducted between 2004 and 2005 to 134 MG samples collected fr... | ['Animals', 'Anti-Bacterial Agents', 'Chickens', 'DNA, Bacterial', 'Drug Resistance, Bacterial', 'Microbial Sensitivity Tests', 'Mycoplasma Infections', 'Mycoplasma gallisepticum', 'Poultry Diseases', 'Random Amplified Polymorphic DNA Technique'] | 17,570,621 | [['B01.050'], ['D27.505.954.122.085'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D13.444.308.212'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['C01.150.252.400.610.610'], ['B03.440.860.580.553.553.345'], ['C22.131.72... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthetic peptides coupled to the surface of liposomes effectively induce SARS coronavirus-specific cytotoxic T lymphocytes and viral clearance in HLA-A*0201 transgenic mice. | We investigated whether the surface-linked liposomal peptide was applicable to a vaccine based on cytotoxic T lymphocytes (CTLs) against severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV). We first identified four HLA-A*0201-restricted CTL epitopes derived from SARS-CoV using HLA-A*0201 transgenic mice and... | ['Adjuvants, Immunologic', 'Animals', 'Cell Line', 'Chlorocebus aethiops', 'Epitopes, T-Lymphocyte', 'HLA-A Antigens', 'HLA-A2 Antigen', 'Humans', 'Liposomes', 'Mice', 'Mice, Transgenic', 'Protein Binding', 'SARS Virus', 'Severe Acute Respiratory Syndrome', 'T-Lymphocytes, Cytotoxic', 'Vaccinia virus', 'Viral Vaccines'... | 19,490,987 | [['D27.505.696.477.067'], ['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D23.050.550.402'], ['D12.776.395.550.489.400', 'D12.776.543.550.439.400', 'D23.050.301.500.100.400', 'D23.050.301.500.450.370', 'D23.050.705.552.100.400', 'D23.050.705.552.450.370'], ['D12.776.395.550.489.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The impact of prolonged rotary ventricular assist device support upon ventricular geometry and flow kinetics. | BACKGROUND: The aim of this study was to determine the impact of prolonged left ventricular assist device (VAD) support on cardiac ventricular geometry and VAD flow kinetics.METHODS: Nineteen patients with end-stage heart failure underwent the implantation of HeartMate II rotary flow VADs. Left and right ventricular ge... | ['Adult', 'Aged', 'Blood Flow Velocity', 'Coronary Circulation', 'Echocardiography', 'Female', 'Heart Failure', 'Heart Ventricles', 'Heart-Assist Devices', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Organ Size', 'Pulsatile Flow', 'Ventricular Dysfunction, Left'] | 21,093,217 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.324'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.434'], ['A07.541.560'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pre-eclampsia presenting as nephrotic syndrome: a case report. | BACKGROUND: Nephrotic syndrome occurring for the first time in pregnancy is rare. We report pre-eclampsia presenting with nephrotic syndrome.METHOD: A case report utilizing the case record and review of relevant literature.RESULTS: A 26-year-old multi-gravida who presented with nephrotic syndrome for the first time in ... | ['Adult', 'Diagnostic Errors', 'Female', 'Humans', 'Nephrotic Syndrome', 'Pre-Eclampsia', 'Pregnancy', 'Pregnancy Complications'] | 15,296,112 | [['M01.060.116'], ['E01.354', 'N02.421.450.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.630.643', 'C13.351.968.419.630.643'], ['C13.703.395.249'], ['G08.686.784.769'], ['C13.703']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. | Epigenetic mechanisms are involved in the pathophysiology of depressive disorders and are unique potential targets for therapeutic intervention. The acetylating agent L-acetylcarnitine (LAC), a well-tolerated drug, behaves as an antidepressant by the epigenetic regulation of type 2 metabotropic glutamate (mGlu2) recept... | ['Acetylation', 'Acetylcarnitine', 'Amino Acids', 'Animals', 'Antidepressive Agents', 'Clomipramine', 'Epigenesis, Genetic', 'Excitatory Amino Acid Antagonists', 'Hippocampus', 'Histone Deacetylases', 'Histones', 'Humans', 'Male', 'Mice', 'Mice, Knockout', 'NF-kappa B', 'Nerve Tissue Proteins', 'Nootropic Agents', 'Pre... | 23,382,250 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D02.092.877.883.099.090'], ['D12.125'], ['B01.050'], ['D27.505.954.427.700.122'], ['D03.633.300.240.194'], ['G05.308.203'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D08.811.277.087.520'... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prothrombotic markers in familial combined hyperlipidemia: evidence of endothelial cell activation and relation to metabolic syndrome. | BACKGROUND: Familial combined hyperlipidemia (FCHL) is characterized by a varied expression of hypertriglyceridemia and hypercholesterolemia within a family, and a high risk of premature coronary artery disease. The present study evaluated a number of potential prothrombotic markers in familial combined hyperlipidemia,... | ['Adult', 'Antithrombin III', 'Blood Coagulation Factors', 'Case-Control Studies', 'Cross-Sectional Studies', 'Female', 'Fibrin Fibrinogen Degradation Products', 'Humans', 'Hyperlipidemia, Familial Combined', 'Lipoproteins', 'Male', 'Middle Aged', 'Peptide Hydrolases', 'Thrombomodulin', 'Triglycerides'] | 15,262,191 | [['M01.060.116'], ['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['D12.776.124.125', 'D23.119'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.87... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Outbreak of pertussis in highly immunized adolescents and its secondary spread to their families. | An outbreak of pertussis was recognized in a highly immunized sixth-grade class of schoolchildren. Among 43 children aged 11-12 years in the class, 38 had been immunized with three doses or more of DTP containing whole-cell pertussis vaccine, two with two doses of DTP and three children were unimmunized. The last DTP v... | ['Child', 'Diphtheria-Tetanus-Pertussis Vaccine', 'Disease Outbreaks', 'Disease Transmission, Infectious', 'Family Health', 'Humans', 'Immunization, Secondary', 'Immunologic Memory', 'Japan', 'Whooping Cough'] | 7,645,380 | [['M01.060.406'], ['D20.215.894.135.535.300', 'D20.215.894.691.263.300', 'D20.215.894.691.824.300', 'D20.215.894.815.300'], ['N06.850.290'], ['N06.850.335'], ['N01.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.485', 'E05.478.550.550'], ['G12.450.050.500'], ['Z01.252.474.463', 'Z01.63... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer. | This study evaluates HLA gene expression and tumor infiltration by B-cells, macrophages, dendritic cells, T-helper and cytotoxic T-lymphocytes in response to short-term preoperative treatment with cyclooxygenase inhibitors. Patients with colorectal carcinoma were randomized to receive oral NSAID (indomethacin or celebr... | ['Adenocarcinoma', 'Aged', 'Aged, 80 and over', 'Anti-Inflammatory Agents, Non-Steroidal', 'Celecoxib', 'Cell Movement', 'Colorectal Neoplasms', 'Cyclooxygenase 2 Inhibitors', 'Cyclooxygenase Inhibitors', 'Dendritic Cells', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'HLA-D Antigens... | 18,307,280 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['G04.198', 'G07.568.500.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.41... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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