Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Gender differences in reported symptoms for acute myocardial infarction: impact on prehospital delay time interval. | A retrospective observational study using database registry of consecutive patients admitted to 16 King County hospital Coronary Care Units (CCU) was conducted to assess gender differences in symptom presentation for acute myocardial infarction (AMI) and investigate how symptom presentation relates to prehospital delay... | ['Age Factors', 'Aged', 'Coronary Care Units', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Patient Acceptance of Health Care', 'Patient Admission', 'Regression Analysis', 'Retrospective Studies', 'Sex Factors', 'Time Factors', 'Transp... | 9,672,451 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['N02.278.388.493.211'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Enuresis, firesetting, and cruelty to animals: does the ego triad show predictive validity? | The hypothesis tested in this study was that the presence of enuresis and cruelty to animals in juvenile firesetters would be significantly related to recidivistic firesetting. This hypothesis was related to Yarnell's belief in an ego triad among juvenile firesetters, which linked the occurrence of enuresis, cruelty to... | ['Adolescent', 'Child', 'Child, Preschool', 'Enuresis', 'Firesetting Behavior', 'Human-Animal Bond', 'Humans', 'Juvenile Delinquency', 'Periodicity', 'Predictive Value of Tests', 'Self Concept', 'Violence'] | 11,817,628 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C12.777.934.284', 'C13.351.968.934.252', 'F01.145.126.856', 'F03.388.400'], ['F03.250.300'], ['F01.145.496.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.479'], ['G01.910.645', 'G07.180.562'], ['E05.318.370.800.650', 'N05.715.360.325.700.6... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Symptomatic cerebrospinal fluid dissemination of cerebral glioblastoma. Computed tomographic findings in 11 cases. | Computed tomography (CT) findings in eleven patients with symptomatic cerebrospinal fluid (CSF) dissemination from cerebral glioblastoma were analyzed and, in seven cases subsequently autopsied, they were compared with histological observations. Each patient had multiple CT abnormalities including periventricular enhan... | ['Adult', 'Aged', 'Brain Neoplasms', 'Cerebral Ventricles', 'Cerebral Ventriculography', 'Child', 'Contrast Media', 'Female', 'Glioma', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Seeding', 'Neoplastic Cells, Circulating', 'Radiographic Image Enhancement', 'Subarachnoid Space', 'Tomography, X-Ray Computed'] | 2,398,940 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A08.186.211.140'], ['E01.370.350.578.937.190', 'E01.370.350.700.560.190', 'E01.370.376.537.750.190', 'E05.629.937.190'], ['M01.060.406'], ['D27.505.259.500', 'D27.720.259'], ['C04.557.465.625.600.380', 'C04.557.470.6... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Prevalent and distinct spliceosomal 3'-end processing mechanisms for fungal telomerase RNA. | Telomerase RNA (TER) is an essential component of the telomerase ribonucleoprotein complex. The mechanism for TER 3'-end processing is highly divergent among different organisms. Here we report a unique spliceosome-mediated TER 3'-end cleavage mechanism in Neurospora crassa that is distinct from that found specifically... | ['Evolution, Molecular', 'Fungi', 'Molecular Sequence Data', 'Neurospora crassa', 'RNA', 'RNA Splicing', 'RNA, Fungal', 'Spliceosomes', 'Telomerase'] | 25,598,218 | [['G05.045.250', 'G16.075.250'], ['B01.300'], ['L01.453.245.667'], ['B01.300.107.800.629.564'], ['D13.444.735'], ['G02.111.760.700', 'G03.839.700', 'G05.308.700.700'], ['D13.444.735.500'], ['A11.284.430.106.279.345.850'], ['D08.811.913.696.445.308.300.750.750', 'D12.776.157.687.613', 'D12.776.157.725.500.921', 'D12.776... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A stress-related explanation to the increased blood pressure and its course following ischemic stroke. | BACKGROUND: A hypertensive response after ischemic stroke is frequent, yet its pathophysiology is unknown. Mechanisms related to local ischemic damage, major vascular occlusion, and psychological stress due to acute illness have been proposed. We assessed the natural course of blood pressure (BP) within the first 24 h ... | ['Aged', 'Aged, 80 and over', 'Blood Pressure', 'Brain Ischemia', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Humans', 'Hypertension', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged', 'Patient Admission', 'Predictive Value of Tests', 'Prospective Studies', 'Registries', 'Risk Factors', 'Stress, Psycholog... | 27,956,837 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E01.370.350.825.500.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['M01.060.116.630'], ['E02.760.400.600... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Negative lead I P waves during anteroseptal accessory pathway orthodromic reciprocating tachycardia. | Although a negative retrograde P wave in lead I during orthodromic reciprocating tachycardia is thought to indicate a left free wall accessory pathway, we describe similar negative P waves in lead I during orthodromic reciprocating tachycardia through anteroseptally situated accessory pathways. | ['Adult', 'Catheter Ablation', 'Diagnosis, Differential', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Tachycardia, Atrioventricular Nodal Reentry', 'Tachycardia, Paroxysmal'] | 9,230,171 | [['M01.060.116'], ['E02.808.750.500', 'E04.014.760.500'], ['E01.171'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.067.845.787.249', 'C14.280.123.875.787.249', 'C23.550.073.845.787.500'], ['C14.280.067.845.695', 'C14.280.123.875.695', 'C23.550.073.845.695']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The RNA structures engaged in replication and transcription of the A59 strain of mouse hepatitis virus. | In addition to the RI (replicative intermediate RNA) and native RF (replicative form RNA), mouse hepatitis virus-infected cells contained six species of RNA intermediates active in transcribing subgenomic mRNA. We have named these transcriptive intermediates (TIs) and native transcriptive forms (TFs) because they are n... | ['Animals', 'Chromatography, Gel', 'Fibroblasts', 'Kinetics', 'Mice', 'Murine hepatitis virus', 'Nuclease Protection Assays', 'Nucleic Acid Conformation', 'Poly A', 'Poly U', 'RNA, Messenger', 'RNA, Viral', 'Ribonuclease T1', 'Ribonuclease, Pancreatic', 'Transcription, Genetic', 'Uridine', 'Virus Replication'] | 11,161,278 | [['B01.050'], ['E05.196.181.400.250'], ['A11.329.228'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['B04.450.580', 'B04.820.578.500.540.150.113.875'], ['E05.393.600'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.550.500'], ['D13.695.578.550.750'], ['D13.444.735.544'], ['D13.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[How to implement a unique triage system in the emergency departments of Latium, Italy]. | Triage is an efficient system that emergency departments (EDs) use to sort out presenting patients on the basis of the speed with which they need treatment. Because triage is not used consistently in the EDs of Latium, a region in central Italy, the regional Public Health Agency (PHA) planned and implemented a regional... | ['Adult', 'Emergency Service, Hospital', 'Female', 'Health Plan Implementation', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Regional Health Planning', 'Triage'] | 19,069,249 | [['M01.060.116'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N03.349.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['N03.349.650'], ['N02.421.297.900']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hang Them High: A Hands-Free Technique for Upper Extremity Limb Holding During Surgical Preparation. | Lifting and holding upper and lower limbs during the "prep and drape" portion of certain orthopaedic procedures exert strong forces on the holder and may lead to musculoskeletal disorders. To address these challenges during upper extremity procedures, this article describes a hand-free elevation and traction technique ... | ['Bandages', 'Extremities', 'Humans', 'Immobilization', 'Lifting', 'Orthopedic Procedures', 'Preoperative Care', 'Upper Extremity'] | 27,851,674 | [['E07.101'], ['A01.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.472'], ['G01.374.669'], ['E02.718', 'E04.555'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795'], ['A01.378.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
DNA microarray-based characterization and antimicrobial resistance phenotypes of clinical MRSA strains from animal hosts. | BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of severe infections in humans and animals worldwide. Studies elucidating the population structure, staphylococcal cassette chromosome mec types, resistance phenotypes, and virulence gene profiles of animal-associated MRSA are needed to u... | ['Animals', 'Cattle', 'Cattle Diseases', 'Dog Diseases', 'Dogs', 'Drug Resistance, Microbial', 'Horse Diseases', 'Horses', 'Methicillin-Resistant Staphylococcus aureus', 'Oligonucleotide Array Sequence Analysis', 'Phenotype', 'Sheep', 'Sheep Diseases', 'Staphylococcal Infections', 'Swine', 'Swine Diseases'] | 32,735,092 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['G06.225', 'G07.690.773.984.269'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['B03.300.390.400.800.750.100.500', 'B03.353.500.750.750.100.500', 'B03.510.100.750.750.100.500', 'B03.5... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of 6 weeks of overfeeding on the body weight, body composition, and energy metabolism of young men. | The effect of overfeeding on the body weight, body fat, water content, energy expenditure, and digestibility of energy and nitrogen was investigated over 42 days in six young men. The metabolic rates in standard situations of work and rest were determined. Energy intakes were apparently increased by 6.2 MJ/day and ener... | ['Adult', 'Body Composition', 'Body Water', 'Body Weight', 'Dietary Carbohydrates', 'Dietary Fats', 'Dietary Proteins', 'Energy Intake', 'Energy Metabolism', 'Humans', 'Lipid Metabolism', 'Male', 'Nutrition Disorders', 'Physical Exertion'] | 7,369,169 | [['M01.060.116'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['A12.207.200'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D12.776.256', 'G07.203.30... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Vibrio alginolyticus infections in the USA, 1988-2012. | Vibrio alginolyticus causes soft tissue and bloodstream infection; little systematically collected clinical and epidemiological information is available. In the USA, V. alginolyticus infections are reported to the Cholera and Other Vibrio Illness Surveillance system. Using data from 1988 to 2012, we categorised infecti... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Risk Factors', 'United States', 'Vibrio Infections', 'Vibrio alginolyticus', 'Young Adult'] | 28,202,099 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['M01.060.703.520'], ... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Phylogenetic relationships in the gymnopoid and marasmioid fungi (Basidiomycetes, euagarics clade). | Three distinct lineages of gymnopoid and marasmioid fungi are recognized in parsimony and Bayesian analyses of nLSU rDNA sequences. One lineage contains the genera Lentinula, Rhodocollybia, Tetrapyrgos, a resurrected and redefined Mycetinis, and two unresolved clades designated /marasmiellus and /gymnopus. /marasmiellu... | ['Basidiomycota', 'DNA, Fungal', 'DNA, Ribosomal', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 28S', 'Sequence Analysis, DNA', 'Sequence Homology'] | 16,392,255 | [['B01.300.179'], ['D13.444.308.300'], ['D13.444.308.475'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.690'], ['E05.393.760.700'], ['G02.111.810', 'G05.810']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin. | The first two cell lineages in the mouse, the surface trophectoderm (TE) and inner cell mass (ICM), are morphologically distinguishable by E3.5, with the outer TE forming a polarized epithelial layer enclosing the apolar ICM. We show here that in mouse embryos completely lacking both maternal and zygotic E-cadherin (ca... | ['Animals', 'Blastocyst', 'Blastocyst Inner Cell Mass', 'CDX2 Transcription Factor', 'Cadherins', 'Cell Differentiation', 'Cell Polarity', 'DNA Primers', 'Ectoderm', 'Epithelium', 'Fluorescent Antibody Technique', 'Genotype', 'Homeodomain Proteins', 'Mice', 'Microscopy, Confocal', 'Transcription Factors'] | 20,826,529 | [['B01.050'], ['A16.254.500'], ['A16.254.500.533'], ['D12.776.260.400.140', 'D12.776.660.201', 'D12.776.930.146'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['G04.152'], ['G04.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A16.504.273'], ['A10.272'], ['E01.370.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A study of the antigenicity and immunogenicity of a new hepatitis B vaccine using a panel of monoclonal antibodies. | The successful prevention of infection with hepatitis B virus (HBV) has been achieved by vaccination with purified hepatitis B surface antigen (HBsAg). The ability of a novel synthetic HBV envelope antigen vaccine (Hep B-3, Hepagene; Medeva), which contains part of the pre-S1 and the complete pre-S2 regions and the who... | ['Antibodies, Monoclonal', 'Antibody Specificity', 'Antigens, Viral', 'Epitope Mapping', 'Female', 'Hepatitis B Surface Antigens', 'Hepatitis B Vaccines', 'Humans', 'Male', 'Recombinant Proteins', 'Vaccines, Synthetic'] | 9,443,102 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['D23.050.327'], ['E05.478.274', 'E05.601.690.300'], ['D23.050.327.495.500.475'], ['D20.215.894.899.955.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.828'], ['D12.776.828.868', 'D20.215.894.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. | The role of monocytes/macrophages in the pathogenesis of ischemia-reperfusion injury (IRI) is unknown. We sought to determine whether activation of macrophage adenosine 2A (A(2A)) receptors (A(2A)Rs) mediates tissue protection. We subjected C57Bl/6 mice infused with clodronate [dichloromethylene bisphosphonate (Cl(2)MB... | ['Acute Kidney Injury', 'Adenosine A2 Receptor Agonists', 'Animals', 'Antimetabolites', 'Cell Line', 'Clodronic Acid', 'Cyclohexanecarboxylic Acids', 'Cytokines', 'Humans', 'Kidney', 'Liposomes', 'Macrophages', 'Mice', 'Mice, Inbred C57BL', 'Purines', 'RNA, Messenger', 'Receptor, Adenosine A2A', 'Reperfusion Injury', '... | 15,561,971 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['D27.505.519.625.725.200.100.200', 'D27.505.696.577.725.200.100.200'], ['B01.050'], ['D27.505.519.186', 'D27.888.569.042'], ['A11.251.210'], ['D02.705.429.500.200'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Follow-up study of twenty-four families with Li-Fraumeni syndrome. | The Li-Fraumeni cancer family syndrome is manifested by susceptibility to breast cancer, sarcomas, and other neoplasms in children and young adults. The present study utilized clinical follow-up data on 545 members of 24 Li-Fraumeni kindreds living and cancer-free at family ascertainment. Two hypotheses were tested bas... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Genes, p53', 'Humans', 'Infant', 'Li-Fraumeni Syndrome', 'Male', 'Middle Aged', 'Pedigree'] | 1,933,872 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Predictors of Reoperation and Failure to Rescue in Bariatric Surgery. | Background and Objectives: Morbidity and mortality have been shown to increase several-fold in patients who have undergone bariatric surgery and returned to the operating room after their initial procedures. Failure-to-rescue (FTR) analyses allow for an understanding of patient management and outcomes that is more dist... | ['Adult', 'Aged', 'Aged, 80 and over', 'Databases, Factual', 'Failure to Rescue, Health Care', 'Female', 'Gastrectomy', 'Gastric Bypass', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Reoperation', 'Risk Factors'] | 29,472,758 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E01.789.800.760.500', 'H01.770.644.145.431.500', 'N04.761.559.590.800.760.500', 'N05.715.360.575.575.800.760.500'], ['E04.210.419'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.45... | ['Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Differences in responses to iron deficiency between two legumes: lentil (Lens culinaris) and chickpea (Cicer arietinum). | Two legumes, lentil and chickpea, were cultivated in nutrient solutions: Fe lacking or containing 30 microM Fe. After 12 days of Fe starvation, lentil showed a severe yellowing of young leaves, a large decrease in chlorophyll concentration, and a significant decline of plant biomass. Chickpea showed a better response t... | ['Chlorophyll', 'Fabaceae', 'Iron', 'Plant Roots', 'Potassium', 'Species Specificity', 'Spectrophotometry, Atomic'] | 16,323,275 | [['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['B01.650.940.800.575.912.250.401'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['A18.400'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['G16.824'], ['E05.196.712.726.551', 'E05.196.867.826.551']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion. | Our understanding of key epigenetic regulators involved in specific biological processes and cancers is still incomplete, despite great progress in genome-wide studies of the epigenome. Here, we carried out a systematic, genome-wide analysis of the functional significance of 615 epigenetic proteins in prostate cancer (... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cell Movement', 'Cell Proliferation', 'Epigenesis, Genetic', 'Gene Expression Regulation, Neoplastic', 'Gene Knockdown Techniques', 'Histone Deacetylases', 'Histone Demethylases', 'Humans', 'Jumonji Domain-Containing Histone Demethylases', 'Male', 'Middle Aged', 'Neoplasm Invasiv... | 22,120,715 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.203'], ['G05.308.370'], ['E05.393.335.500'], ['D08.811.277.087.520'], ['D08.811.682.662.582.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.662.582.475.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhanced Lineage-Specific Differentiation Efficiency of Human Induced Pluripotent Stem Cells by Engineering Colony Dimensionality Using Electrospun Scaffolds. | Electrospun scaffolds with varied stiffness promote distinct colony morphology of human induced pluripotent stem cells, which affects their subsequent differentiation. On soft scaffolds, induced pluripotent stem cells develop 3D colonies due to the pliability of the electrospun fibrous networks, leading to greater diff... | ['Cell Differentiation', 'Humans', 'Induced Pluripotent Stem Cells', 'Tissue Scaffolds'] | 27,187,808 | [['G04.152'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['E07.206.627', 'E07.695.825']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An epidemiological study of obesity in Shimla Town. | A cross sectional study of 888 randomly selected subjects in Shimla town was done to determine prevalence of obesity, its relation to age and physical activity. The prevalence of obesity was 21.5% using cut off levels of BMI 25. The prevalence of obesity rose significantly with age. Obesity was less in those having mod... | ['Adult', 'Body Mass Index', 'Cross-Sectional Studies', 'Humans', 'India', 'Middle Aged', 'Morbidity', 'Obesity', 'Prevalence', 'Random Allocation', 'Retrospective Studies', 'Risk Factors', 'Survival Rate', 'Urban Population'] | 9,057,371 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['E05.318.308.985.525', 'N01.224.935.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Experience with unipolar radiofrequency ablation for atrial fibrillation. | BACKGROUND: The cut and sew Cox maze procedure for atrial fibrillation (AF), although effective, is not widely used because of technical complexity, prolonged duration and significant risk of postoperative bleeding. This study reviews our experience with the unipolar radiofrequency ablation (RFA) procedure, which was u... | ['Aged', 'Aged, 80 and over', 'Atrial Fibrillation', 'Catheter Ablation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies'] | 16,922,895 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067.198', 'C23.550.073.198'], ['E02.808.750.500', 'E04.014.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.8... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reversal of the histology of bone after parathyroidectomy in patients with hyperparathyroidism. | Hyperparathyroidism is commonly seen in patients with end-stage renal disease and less commonly in the primary form. The skeletal manifestations of hyperparathyroidism are the same in both forms and are well described in the literature. We treated a patient from each category. Multiple bony lesions and pathologic fract... | ['Adult', 'Aged', 'Fibula', 'Fractures, Spontaneous', 'Humans', 'Humeral Fractures', 'Hyperparathyroidism', 'Hyperparathyroidism, Secondary', 'Male', 'Parathyroidectomy', 'Tibial Fractures'] | 9,570,733 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.232.043.650.321'], ['C26.404.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.088.390', 'C26.404.500'], ['C19.642.355'], ['C19.642.355.480'], ['E04.270.694'], ['C26.404.875', 'C26.558.857']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preliminary investigation on hemocompatibility of poly(vinylidene fluoride) membrane grafted with acryloylmorpholine via ATRP. | This work provides a promising way to improve the hemocompatibility of PVDF membrane. An amphiphilic copolymer (PVDF-g-PACMO) having PVDF backbones and poly(N-acryloylmorpholine) (PACMO) side chains was synthesized via atom transfer radical polymerization (ATRP). It is found that the grafting degree of the PACMO increa... | ['Acrylamides', 'Animals', 'Blood Platelets', 'Cattle', 'Hemolysis', 'Materials Testing', 'Membranes, Artificial', 'Morpholines', 'Platelet Adhesiveness', 'Polyvinyls'] | 24,789,814 | [['D02.065.122', 'D02.241.081.069.094'], ['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.500.380.271'], ['C23.550.403', 'G12.122.545'], ['E05.570'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D03.383.533.640'], ['G09.188.390.600.500', 'G09.188.670'], ['D02.455.326.271.665.616', 'D02... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Non-operative treatment of unicompartmental osteoarthritis of the knee: a prospective randomized trial with two different braces-ankle-foot orthosis versus knee unloader brace. | BACKGROUND: The use of an unloader brace is a non-surgical treatment option for patients with medial osteoarthritis (OA). However, many patients do not adhere to brace treatment, because of skin irritation due to the pads at the level of the joint space and bad fit. A new concept to unload the medial compartment of the... | ['Adult', 'Aged', 'Ankle Joint', 'Braces', 'Conservative Treatment', 'Female', 'Foot Orthoses', 'Humans', 'Knee Joint', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Pain', 'Patient Compliance', 'Quality of Life', 'Treatment Outcome', 'Walking'] | 30,255,369 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.583.378.062'], ['E07.858.442.743.319'], ['E02.197'], ['E07.858.442.743.659'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'],... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Individual risk screening and visualization as a central element of health days through the interactive electronic GloRiA program]. | BACKGROUND: Health days are an established forum for prevention and health promotion for different groups in the general population. Through the use of modular questionnaires "Global Risk Assessment" (GloRiA) on computers (handheld and desktop), the recording of patient data and presentation of the results can be optim... | ['Adult', 'Aged', 'Body Mass Index', 'Cardiovascular Diseases', 'Comorbidity', 'Diagnosis, Computer-Assisted', 'Early Diagnosis', 'Electronic Health Records', 'Female', 'Germany', 'Health Promotion', 'Humans', 'Internet', 'Male', 'Mass Screening', 'Middle Aged', 'Risk Assessment', 'Risk-Taking', 'Smoking', 'Software', ... | 23,964,471 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.390'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Extracellular release of peroxidase from eosinophils by interaction with immune complexes. | Much peroxidase is released from eosinophils that ingest complexes formed of human immunoglobulins with specific rabbit antibody. The complex formed of IgE with rabbit antibody, was particularly effective. The amount and rate of release of peroxidase was closely related to the amounts of complex ingested by the eosinop... | ['Antibodies, Anti-Idiotypic', 'Antigen-Antibody Complex', 'Eosinophils', 'Humans', 'Immunoglobulin E', 'In Vitro Techniques', 'Microscopy, Electron', 'Peroxidases'] | 301,076 | [['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.64... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional studies of human GLUT5: effect of pH on substrate selection and an analysis of substrate interactions. | The adsorption of D-fructose within the lumen of the human small intestine is thought to be mediated by the GLUT5 isoform of the human facilitative sugar transporter family. This isoform has been expressed in oocytes and shown to be capable of D-fructose transport. Some debate remains regarding the absolute substrate s... | ['Glucose Transporter Type 5', 'Humans', 'Hydrogen-Ion Concentration', 'Monosaccharide Transport Proteins', 'Substrate Specificity'] | 9,299,540 | [['D12.776.157.530.500.500.968', 'D12.776.157.530.937.563.968', 'D12.776.543.585.500.500.968', 'D12.776.543.585.937.625.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D12.776.157.530.500', 'D12.776.543.585.500'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The impact of quality-reporting programs on hospital operations. | We used data from the 2005-06 Community Tracking Study site visits to examine the impact of quality reporting on hospitals' data collection and review processes, feedback and accountability mechanisms, quality improvement activities, and resource allocation. Individual hospitals participate in multiple, varied reportin... | ['Disclosure', 'Feedback', 'Hospitals, Community', 'Humans', 'Quality Assurance, Health Care', 'Quality Indicators, Health Care', 'Social Responsibility', 'United States'] | 16,966,741 | [['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['L01.906.394.211'], ['N02.278.421.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700', 'N05.700'], ['N04.761.789', 'N05.715.760'], ['F01.829.500.760', 'K01.752.566.869'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
[Breast cancer metastasized to the pararenal fat 26 years after mastectomy : a case report]. | A 66-year-old woman was referred to our hospital with a right renal tumor in October 2010. In 1984, she underwent a mastectomy because of left breast cancer. In 2006, she underwent a lobectomy because of right lung cancer. A follow-up computed tomography of the lung cancer revealed a right renal tumor which extended to... | ['Adenocarcinoma', 'Adipose Tissue', 'Aged', 'Breast Neoplasms', 'Female', 'Humans', 'Kidney Neoplasms', 'Lung Neoplasms', 'Mastectomy'] | 23,552,754 | [['C04.557.470.200.025'], ['A10.165.114'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E04.4... | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
MyoD gene suppression by Oct4 is required for reprogramming in myoblasts to produce induced pluripotent stem cells. | Expression of the four transcription factors, that is, Oct4, Sox2, cMyc, and Klf4 has been shown to generate induced pluripotent stem cells (iPSCs) from many types of specialized differentiated somatic cells. It remains unclear, however, whether fully committed skeletal muscle progenitor cells (myoblasts) have the pote... | ['Animals', 'Cells, Cultured', 'Cellular Reprogramming', 'Down-Regulation', 'Female', 'Induced Pluripotent Stem Cells', 'Mice', 'Mice, Inbred ICR', 'Mice, Inbred NOD', 'Mice, Knockout', 'Mice, SCID', 'MyoD Protein', 'Myoblasts', 'Octamer Transcription Factor-3', 'Pregnancy'] | 21,425,413 | [['B01.050'], ['A11.251'], ['G04.152.262', 'G05.135'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A11.872.040.500', 'A11.872.700.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['B01.050.050.199.520.520.565', 'B01.050.150.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interindividual and interethnic variation in genomewide gene expression: insights into the biological variation of gene expression and clinical implications. | BACKGROUND: Analysis of gene expression in peripheral blood samples is increasingly being applied in biomarker studies of disease diagnosis and prognosis. Although knowledge of interindividual and interethnic variation in gene expression is required to set ethnicity-specific reference intervals and to select reference ... | ['Cell Line', 'Gene Expression Regulation', 'Genome, Human', 'Humans', 'Lymphocytes', 'Mutation', 'Transcription, Genetic'] | 19,233,909 | [['A11.251.210'], ['G05.308'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['G05.365.590'], ['G02.111.873', 'G05.297.700']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Absence of gamma-interferon-inducible lysosomal thiol reductase (GILT) is associated with poor disease-free survival in breast cancer patients. | Tumor immunosurveillance is known to be of critical importance in controlling tumorigenesis and progression in various cancers. The role of gamma-interferon-inducible lysosomal thiol reductase (GILT) in tumor immunosurveillance has recently been studied in several malignant diseases, but its role in breast cancer remai... | ['Adult', 'Aged', 'Body Mass Index', 'Breast Neoplasms', 'Disease-Free Survival', 'Female', 'Humans', 'Immunohistochemistry', 'Ki-67 Antigen', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Staging', 'Oligonucleotide Array Sequence Analysis', 'Oxidoreductases Acting on Sulfur Group Donors', 'RNA, Messenger', 'Real-Ti... | 25,333,930 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.180', 'C17.800.090.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.30... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical implementation of a reactive balance control assessment in a sub-acute stroke patient population using a 'lean-and-release' methodology. | Reactive balance control, specifically performance of rapid stepping responses, is associated with falls, but not routinely assessed in clinical practice. Challenges to clinical assessment may include a lack of available methods that are safe, standardized and able to quantify the balance responses. We implemented a re... | ['Aged', 'Female', 'Gait Disorders, Neurologic', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Mobility Limitation', 'Physical Therapy Modalities', 'Postural Balance', 'Recovery of Function', 'Retrospective Studies', 'Stroke', 'Stroke Rehabilitation', 'Walking'] | 25,596,621 | [['M01.060.116.100'], ['C10.597.404', 'C23.888.592.413'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['C23.888.550'], ['E02.779', 'E02.831.535'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['G16.757'], ['E05.31... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Genotypic and phenotypic analysis of type III secretion system in a cohort of Pseudomonas aeruginosa bacteremia isolates: evidence for a possible association between O serotypes and exo genes. | The type III secretion system (TTSS) of Pseudomonas aeruginosa was characterized genetically and phenotypically in 92 epidemiologically unrelated bacteremic strains. Four groups of strains (TTSS types) were defined according to the level of type III protein secretion and kinetics of cytotoxicity. Type 1 strains (n=26) ... | ['ADP Ribose Transferases', 'Animals', 'Bacteremia', 'Bacterial Proteins', 'Bacterial Toxins', 'Cell Line', 'Cytotoxicity Tests, Immunologic', 'Genes, Bacterial', 'Genotype', 'Humans', 'Macrophages', 'Mice', 'Phenotype', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Serotyping'] | 12,898,437 | [['D08.811.913.400.725.115'], ['B01.050'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['D12.776.097'], ['D23.946.123'], ['A11.251.210'], ['E01.370.225.812.160', 'E05.200.812.160', 'E05.478.594.160', 'E05.940.245'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relation between dose, plasma concentration and toxicity in a phase I trial using high dose intermittent administration of an alkylating agent, diacetyldianhydrogalactitol (DADAG). | Diacetyldianhydrogalactitol (DADAG), a new alkylating sugar alcohol derivative, was administered as single, 30-min infusions in doses ranging from 390 to 1200 mg/m2. The dose-limiting toxicity was myelosuppression. The median times to WBC nadir and regeneration were 16 and 21 days, and to platelet nadir and recovery 20... | ['Adult', 'Aged', 'Antimetabolites', 'Antineoplastic Agents', 'Dianhydrogalactitol', 'Dose-Response Relationship, Drug', 'Drug Evaluation', 'Female', 'Hematopoietic Stem Cells', 'Humans', 'Leukocyte Count', 'Male', 'Middle Aged', 'Platelet Count', 'Sugar Alcohols', 'Vomiting'] | 3,698,168 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.186', 'D27.888.569.042'], ['D27.505.954.248'], ['D02.033.800.400.350', 'D09.853.400.350'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.625', 'E05.337.425'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Capitellum fractures: a biomechanical evaluation of three fixation methods. | OBJECTIVE: To determine the relative stability of three fixation methods for displaced capitellum fractures.DESIGN: Twelve matched pairs of embalmed humeri were divided into two equal groups and simulated capitellum fractures created. The first group compared cancellous lag screws placed in an anteroposterior direction... | ['Biomechanical Phenomena', 'Bone Screws', 'Elbow Joint', 'Fracture Fixation', 'Fractures, Bone', 'Humans', 'Humeral Fractures', 'Joint Instability', 'Radiography', 'Weight-Bearing'] | 12,172,281 | [['G01.154.090', 'G01.374.089'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['A02.835.583.290'], ['E04.555.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.088.390', 'C26.404.500'], ['C05.550.521'], ['E01.370.350.700'], ['G01.374.965']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Resonance frequency measurements in vivo and related surface properties of magnesium-incorporated, micropatterned and magnesium-incorporated TiUnite, Osseotite, SLA and TiOblast implants. | OBJECTIVE: To investigate implant stability using resonance frequency measurements of topographically changed and/or surface chemistry-modified implants in rabbit bone.MATERIAL AND METHODS: Six groups of microstructured, screw-shaped titanium implants: two oxidized, cation-incorporated experimental implants [Mg implant... | ['Animals', 'Bone Density', 'Dental Alloys', 'Dental Implantation, Endosseous', 'Dental Implants', 'Dental Prosthesis Design', 'Dental Prosthesis Retention', 'Dental Restoration Failure', 'Dental Stress Analysis', 'Implants, Experimental', 'Magnesium', 'Osseointegration', 'Rabbits', 'Stress, Mechanical', 'Surface Prope... | 19,719,742 | [['B01.050'], ['G11.427.100'], ['D25.339.208', 'J01.637.051.339.208'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.625', 'E06.912.145'], ['E06.780.346.687'], ['E06.323.400', 'E06.780.346.725... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Functional characterization of visual opsin repertoire in Medaka (Oryzias latipes). | A variety of visual pigment repertoires present in fish species is believed due to the great variation under the water of light environment. A complete set of visual opsin genes has been isolated and characterized for absorption spectra and expression in the retina only in zebrafish. Medaka (Oryzias latipes) is a fish ... | ['Animals', 'Base Sequence', 'DNA Primers', 'Evolution, Molecular', 'Gene Expression', 'Oryzias', 'Phylogeny', 'Reverse Transcriptase Polymerase Chain Reaction', 'Rod Opsins'] | 16,460,888 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.045.250', 'G16.075.250'], ['G05.297'], ['B01.050.150.900.493.850.139.650'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.620.500.725'], ['D12.776.306.466.500', 'D23.767.930.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Analysis of clinical features and the outcome in 91 cases of mixed connective tissue diseases]. | OBJECTIVE: To investigate the clinical features and prognosis of mixed connective tissue disease (MCTD).METHODS: Clinical, laboratory and instrumental examination information of 91 patients with MCTD,who were diagnosed between 1990 to 2008 in Peking University People's Hospital, were collected and analyzed retrospecti... | ['Adolescent', 'Adult', 'Aged', 'Autoantibodies', 'Child', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Mixed Connective Tissue Disease', 'Prognosis', 'Retrospective Studies', 'Young Adult'] | 22,517,002 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['M01.060.406'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Morphine diesters. I. Synthesis and action on guinea pig ileum. | 3,6-Dipropanoylmorphine (DPM), 3,6-dibutanoylmorphine (DBM), and 3,6-dihexanoylmorphine (DHM) were prepared as prospective long-acting narcotic analgesics. The purity and structure of these compounds were authenticated by high pressure liquid chromatography and direct probe mass spectrometry. In aqueous solution the st... | ['Animals', 'Chromatography, High Pressure Liquid', 'Guinea Pigs', 'Heroin', 'In Vitro Techniques', 'Mass Spectrometry', 'Morphine Derivatives', 'Muscle Contraction', 'Muscle, Smooth'] | 6,733,591 | [['B01.050'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.992.550'], ['D03.132.577.249.562.445', 'D03.605.497.607.490', 'D03.633.400.686.607.490', 'D04.615.723.795.576.445'], ['E05.481'], ['E05.196.566'], ['D03.132.577.249.562', 'D03.605.497.607', 'D03.633.400.686.607', 'D04.615.723.795.576'], ['G11.427.494'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Linolenic acid deficiency: changes in fatty acid patterns in female and male rats raised on a linolenic acid-deficient diet for two generations. | Rats were fed for two generations a purified, linolenic acid-deficient diet in which the only source of lipid was purified methyl linoleate. This diet contained about 38 mg linolenic acid/kg diet. Control rats were given the same diet supplemented with methyl linolenate (2,500 mg/kg diet). Male and female rats ranged i... | ['Age Factors', 'Animals', 'Body Weight', 'Deficiency Diseases', 'Diet', 'Female', 'Growth', 'Linoleic Acids', 'Male', 'Membrane Lipids', 'Organ Size', 'Rats', 'Sex Factors'] | 628,317 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.654.521.500'], ['G07.203.650.240'], ['G07.345.249'], ['D10.251.355.310.515', 'D10.251.355.343.500'], ['D10.570'], ['E01.370.600.115.100.660', '... | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of calorie restriction on reproductive and adrenal systems in Japanese quail: are responses similar to mammals, particularly primates? | The benefits of calorie restriction (CR) have been established across a variety of vertebrate and invertebrate species. Although the effects of CR on lifespan in birds have not been examined, it is clear that CR has beneficial effects on reproductive, metabolic, and physiological function in adult poultry. We examined ... | ['Adrenal Glands', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Caloric Restriction', 'Catecholamines', 'Coturnix', 'Diet', 'Gonadotropin-Releasing Hormone', 'Hormones', 'Hypothalamus', 'Male', 'Mammals', 'Primates', 'Reproduction', 'Species Specificity'] | 15,935,442 | [['A06.300.071'], ['G07.203.650.161'], ['B01.050'], ['E02.642.249.200', 'G07.203.650.240.340.150'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['B01.050.150.900.248.350.650.350'], ['G07.203.650.240'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. | Cannabinoids (CB) modulate adult hematopoietic stem and progenitor cell (HSPCs) function, however, impact on the production, expansion, or migration of embryonic HSCs is currently uncharacterized. Here, using chemical and genetic approaches targeting CB-signaling in zebrafish, we show that CB receptor (CNR) 2, but not ... | ['Animals', 'Dinoprostone', 'Hematopoietic Stem Cells', 'P-Selectin', 'Receptor, Cannabinoid, CB1', 'Receptor, Cannabinoid, CB2', 'Signal Transduction', 'Zebrafish', 'Zebrafish Proteins'] | 25,931,248 | [['B01.050'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['D12.776.395.550.200.700.775', 'D12.776.395.550.625.905', 'D12.776.503.843.775', 'D12.776.543.550.200.700.775', 'D12.776.543.550.625.905', 'D23.050.301.350.700.775'], ['D12.776.543.750.695.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Deep Metaproteomics Approach for the Study of Human Microbiomes. | Host-microbiome interactions have been shown to play important roles in human health and diseases. Most of the current studies of the microbiome have been performed by genomic approaches through next-generation sequencing. Technologies, such as metaproteomics, for functional analysis of the microbiome are needed to bet... | ['Bacterial Proteins', 'Child', 'Chromatography, Liquid', 'Computational Biology', 'Feces', 'Gastrointestinal Microbiome', 'Genomics', 'Humans', 'Mass Spectrometry', 'Microbiota', 'Proteomics'] | 28,749,657 | [['D12.776.097'], ['M01.060.406'], ['E05.196.181.400'], ['H01.158.273.180', 'L01.313.124'], ['A12.459'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['G06.591', 'G16.5... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke. | Stimulation of endogenous neural stem/progenitor cells (NSPCs) with therapeutic factors holds potential for the treatment of stroke. Cyclosporin A (CsA) is a particularly promising candidate molecule because it has been shown to act as a survival factor for these cells over a period of weeks both in vitro and in vivo; ... | ['Animals', 'Brain', 'Chromatography, Liquid', 'Cyclosporine', 'Delayed-Action Preparations', 'Drug Delivery Systems', 'Hyaluronic Acid', 'Hydrogels', 'Lactic Acid', 'Methylcellulose', 'Mice', 'Mice, Inbred C57BL', 'Microscopy, Electron, Scanning', 'Microspheres', 'Models, Biological', 'Neural Stem Cells', 'Particle Si... | 23,306,024 | [['B01.050'], ['A08.186.211'], ['E05.196.181.400'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['D26.255.210', 'E02.319.300.253'], ['E02.319.300'], ['D09.698.373.475'], ['D20.280.320.375', 'D26.255.165.320.375'], ['D02.241.511.459.450'], ['D09.698.365.180.663'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.0... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Laminar flow stimulates ATP- and shear stress-dependent nitric oxide production in cultured bovine endothelial cells. | Based on the fact that nitric oxide (NO) production is associated with changes in intracellular cGMP levels and is selectively inhibited by N omega-methyl L-arginine (L-NME), we investigated the shear stress dependency of NO production in endothelial cells (ECs) from its cGMP responses to various shear stress loads. Cu... | ['1-Methyl-3-isobutylxanthine', 'Adenosine Triphosphate', 'Animals', 'Aorta, Thoracic', 'Arginine', 'Calcium', 'Cattle', 'Cells, Cultured', 'Cyclic GMP', 'Egtazic Acid', 'Endothelium, Vascular', 'Fetus', 'Kinetics', 'Nitric Oxide', 'Stress, Mechanical', 'omega-N-Methylarginine'] | 7,507,319 | [['D03.633.100.759.758.824.751.500'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A07.015.114.056.372'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Balance of beneficial and deleterious health effects of quinones: a case study of the chemical properties of genistein and estrone quinones. | Substances containing a phenolic moiety are often metabolized to quinones whose high reactivity makes them difficult to study. Some of these precursors have clear health benefits, and some quinones themselves are used in cancer therapy, whereas others are deleterious. For example, dietary intake of phytoestrogen, genis... | ['Catechols', 'DNA', 'Estrone', 'Genistein', 'Health', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Molecular Structure', 'Quinones', 'Reactive Oxygen Species', 'Time Factors', 'Water'] | 19,115,854 | [['D02.455.426.559.389.657.166'], ['D13.444.308'], ['D04.210.500.365.415.414', 'D04.210.500.578.502.497', 'D06.472.040.502.497', 'D06.472.334.851.437.996'], ['D03.383.663.283.266.450.400.375', 'D03.633.100.150.266.450.400.375'], ['N01.400'], ['E05.196.867.519'], ['E05.196.566'], ['G02.111.570', 'G02.466'], ['D02.806'],... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Daily psychosocial stressors interfere with the dynamics of urine neopterin in a patient with systemic lupus erythematosus: an integrative single-case study. | OBJECTIVE: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by flare-ups, the causes of which are not known. In accordance with new concepts in stress research, this study investigated whether daily psychosocial stressors interfere with immunological processes in SLE. Because such proces... | ['Adult', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Neopterin', 'Psychoneuroimmunology', 'Recurrence', 'Research Design', 'Stress, Psychological'] | 10,593,641 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['D03.633.100.733.631.202.500', 'D08.211.090.500'], ['F04.096.795.650', 'H01.158.782.795.180'], ['C23.550.291.937'], ['E05.581.500', 'H01.770.644.728'], ['F01.145.126.990', 'F02.830.900']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors. | Bile acids exert genomic and nongenomic effects by interacting with membrane G-protein-coupled receptors, including the bile acid receptor GP-BAR1, and nuclear receptors, such as the farnesoid X receptor (FXR). These receptors regulate overlapping metabolic functions; thus, GP-BAR1/FXR dual agonists, by enhancing the b... | ['Cholanes', 'Drug Design', 'HEK293 Cells', 'Humans', 'Hypoglycemic Agents', 'Molecular Docking Simulation', 'Protein Binding', 'Receptors, Cytoplasmic and Nuclear', 'Receptors, G-Protein-Coupled', 'Stereoisomerism', 'Structure-Activity Relationship', 'Transcriptional Activation'] | 24,387,325 | [['D04.210.500.221'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['E05.599.595.249', 'L01.224.160.249'], ['G02.111.679', 'G03.808'], ['D12.776.826'], ['D12.776.543.750.695'], ['G02.607.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Addressing weight-related issues in an elementary school: what do students, parents, and school staff recommend? | This study examined weight-related issues affecting elementary school children to gain insight into how best to address these issues within a school-based intervention. The study population included 21 students, 12 school staff members, and 21 parents from a school that serves an ethnically-diverse population. Data wer... | ['Body Image', 'Body Weight', 'Child', 'Counseling', 'Faculty', 'Female', 'Focus Groups', 'Health Education', 'Humans', 'Interview, Psychological', 'Male', 'Parents', 'Social Desirability', 'Students'] | 17,162,638 | [['F01.752.747.792.110', 'F02.463.593.112'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['M01.526.702.250'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.85... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Time course of bronchoconstriction induced by dry gas hyperpnea in guinea pigs. | We examined the effects of hyperpnea duration and abrupt changes in inspired gas heat and water content on the magnitude and time course of hyperpnea-induced bronchoconstriction (HIB) in anesthetized mechanically ventilated male Hartley guinea pigs. In 12 animals subjected to 5, 10, and 15 min (random order) of dry gas... | ['Airway Resistance', 'Animals', 'Body Temperature Regulation', 'Body Water', 'Bronchi', 'Gases', 'Guinea Pigs', 'Humidity', 'Kinetics', 'Male', 'Muscle Contraction', 'Propranolol', 'Respiration'] | 2,022,539 | [['E01.370.386.700.050', 'G09.772.060'], ['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['A12.207.200'], ['A04.411.125'], ['D01.362'], ['B01.050.150.900.649.313.992.550'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['G01.374.661', 'G02.111.490'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vivo fracture of a basket-type osseointegrating dental implant: a case report. | Complete circumferential fracture of a basket-type implant 12 months postrestoration is described. | ['Adult', 'Dental Implantation, Endosseous', 'Dental Implants', 'Equipment Failure', 'Humans', 'Male', 'Osteogenesis'] | 2,639,124 | [['M01.060.116'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Rac2 is involved in bleomycin-induced lung inflammation leading to pulmonary fibrosis. | BACKGROUND: Pulmonary fibrotic diseases induce significant morbidity and mortality, for which there are limited therapeutic options available. Rac2, a ras-related guanosine triphosphatase expressed mainly in hematopoietic cells, is a crucial molecule regulating a diversity of mast cell, macrophage, and neutrophil funct... | ['Animals', 'Bleomycin', 'Female', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Pneumonia', 'Pulmonary Fibrosis', 'rac GTP-Binding Proteins'] | 24,970,330 | [['B01.050'], ['D09.400.420.110', 'D12.644.233.110'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['C01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nerve growth factor reduces apoptotic cell death in rat facial motor neurons after facial nerve injury. | OBJECTIVE: To assess the effects of nerve growth factor (NGF) on motor neurons after induction of a facial nerve lesion, and to compare the effects of different routes of NGF injection on motor neuron survival.METHODS: This study was carried out in the Department of Otolaryngology Head & Neck Surgery, China Medical Uni... | ['Animals', 'Apoptosis', 'Caspase 3', 'Disease Models, Animal', 'Facial Nerve', 'Facial Nerve Injuries', 'Immunohistochemistry', 'Male', 'Motor Neurons', 'Nerve Growth Factor', 'Rats, Wistar'] | 25,630,785 | [['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis, characterization and in vitro evaluation of new composite bisphosphonate delivery systems. | In this study, new composite bisphosphonate delivery systems were obtained from polyurethanes (PUs) and nanocrystalline hydroxyapatite (HA). The biodegradable PUs were first synthesized from poly(å-caprolactone) diols (PCL diols), poly(ethylene adipate) diol, 1,6-hexamethylene diisocyanate, 1,4-butanediol and HA. Moreo... | ['Absorbable Implants', 'Aliivibrio fischeri', 'Biocompatible Materials', 'Ciliophora', 'Clodronic Acid', 'Diphosphonates', 'Drug Carriers', 'Drug Implants', 'Durapatite', 'In Vitro Techniques', 'Materials Testing', 'Microscopy, Electron, Scanning', 'Nanoparticles', 'Polyurethanes', 'Porosity', 'Tetrahymena thermophila... | 25,247,580 | [['E07.695.025'], ['B03.440.450.900.050.860', 'B03.660.250.830.050.860'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['B01.043.185'], ['D02.705.429.500.200'], ['D02.705.429.500'], ['D26.255.260', 'E02.319.300.380'], ['D26.255.210.315'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Eosinophil apoptosis in nasal polyposis tissue after bleomycin A5 local injection]. | OBJECTIVE: To study the expression of eosinophil in nasal polyposis tissue after Bleomycin A5 local injection.METHOD: Nineteen cases nasal polyposis specimen obtained before and after treatment with Bleomycin A5 were studied with terminal deoxynucleotidyl transferasemediated dUTP nick endlabeling (TUNEL).RESULT: The nu... | ['Adult', 'Aged', 'Antibiotics, Antineoplastic', 'Apoptosis', 'Bleomycin', 'Eosinophils', 'Female', 'Humans', 'Injections, Intralesional', 'Male', 'Middle Aged', 'Nasal Polyps'] | 15,311,509 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248.106'], ['G04.146.954.035'], ['D09.400.420.110', 'D12.644.233.110'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.430'], ['M01.060.116.630'], ['C08.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adiposity indices in German children and adolescents with genetically confirmed Prader-Willi syndrome (PWS). | BACKGROUND: Morbid obesity develops as a result of hyperphagia and compulsive eating behavior in patients with Prader-Willi syndrome (PWS), if caloric intake is not rigorously controlled. PWS-specific centile curves for adiposity indices constructed in the past were based on clinically diagnosed patients. With the adve... | ['Adolescent', 'Adult', 'Anthropometry', 'Body Constitution', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Germany', 'Humans', 'Male', 'Obesity, Morbid', 'Prader-Willi Syndrome', 'Reference Values', 'Skinfold Thickness', 'United States'] | 11,466,581 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115', 'G07.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Local drug delivery with porous balloons in the rabbit: assessment of vascular injury for an improvement of application parameters. | OBJECTIVES: Sufficient intramural drug concentrations with the use of porous balloon catheters can be achieved with additional vascular trauma only. However, effective delivery of a potent drug even in deeper layers of the vessel wall might outweigh these traumatic side effects. Given the porous balloon catheter, the p... | ['Angioplasty, Balloon, Coronary', 'Animals', 'Carotid Arteries', 'Coronary Artery Disease', 'Dose-Response Relationship, Drug', 'Drug Delivery Systems', 'Elastic Tissue', 'Equipment Failure Analysis', 'Fibrinolytic Agents', 'Fibromuscular Dysplasia', 'Heparin, Low-Molecular-Weight', 'Hydrostatic Pressure', 'Muscle, Sm... | 9,213,030 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['B01.050'], ['A07.015.114.186'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['G07.690.77... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Five new eudesmane-type sesquiterpenoid lactones biotransformed from atractylenolide I by rat hepatic microsomes. | The work presented here is the first study performed on the biotransformation and/or metabolism of atractylenolide I (1) as a valuable anti-inflammatory and chemopreventive agent, using liver microsomes from rats pre-treated with sodium phenobarbital. Two known eudesmane-type sesquiterpenoid lactones, namely 1â-acetoxy... | ['Animals', 'Atractylodes', 'Biotransformation', 'Lactones', 'Microsomes, Liver', 'Phenobarbital', 'Plants, Medicinal', 'Rats', 'Sesquiterpenes', 'Sesquiterpenes, Eudesmane'] | 23,321,568 | [['B01.050'], ['B01.650.940.800.575.912.250.100.126'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D02.540'], ['A11.284.835.540.541'], ['D03.383.742.698.253.650'], ['B01.650.560'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.455.849.765'], ['D02.455.849.765.674.500', 'D04.663.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anesthetic management of neck trauma. | In a retrospective review of one year's experience in the management of neck trauma, 88 cases comprising 42 gunshot wounds, 29 stab or slash injuries, and 17 injuries by blunt trauma were reviewed. Multiple injuries were noted in all groups, but a higher percentage was found in the blunt trauma series. Anesthetic manag... | ['Adolescent', 'Adult', 'Anesthesia, Endotracheal', 'Carotid Artery Injuries', 'Child', 'Esophagus', 'Facial Injuries', 'Female', 'Humans', 'Intubation, Intratracheal', 'Larynx', 'Male', 'Neck Injuries', 'Pharynx', 'Spinal Cord Injuries', 'Trachea', 'Tracheotomy', 'Wounds, Gunshot', 'Wounds, Nonpenetrating', 'Wounds, S... | 472,830 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cannulation of congenital lacrimal duct obstruction]. | During the development of a Czechoslovak silicone cannula for reconstructive surgery of the lacrimal passage-ways was elaborated the modification for the congenital obstruction. The surgical method imoles the probing and cannulation at the same time. probe with fixed cannula passed delicately through nasolacrimal duct ... | ['Humans', 'Intubation', 'Lacrimal Duct Obstruction'] | 9,296,859 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.585', 'E05.497'], ['C11.496.456']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma. | The purpose of this study was to improve a mouse model of chronic intraocular pressure (IOP) elevation utilizing microbead injection in two strains of mice and to assess the effect of age and anesthesia on measured IOP. We compared our previous model with two modified protocols for injecting polystyrene microbeads and ... | ['Acepromazine', 'Aging', 'Anesthesia', 'Anesthetics, Dissociative', 'Anesthetics, Inhalation', 'Animals', 'Axons', 'Cell Count', 'Disease Models, Animal', 'Glaucoma', 'Injections, Intraperitoneal', 'Intraocular Pressure', 'Isoflurane', 'Ketamine', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Microspheres', 'Opti... | 22,554,836 | [['D02.886.369.029', 'D03.633.300.783.029'], ['G07.345.124'], ['E03.155'], ['D27.505.696.277.100.035.075.035', 'D27.505.954.427.210.100.035.075.035'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['E01.370.225.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relative importance of identity status interview components: replication and extension. | The present study partially replicates and extends the work of Rogow et al. (1983) in probing the relative importance of Ego Identity Status Interview components for both sexes. Eighty female and sixty male students attending a New Zealand university were given the Ego Identity Status Interview with identity components... | ['Adolescent', 'Adult', 'Ego', 'Female', 'Gender Identity', 'Humans', 'Interview, Psychological', 'Male', 'Occupations', 'Politics', 'Religion and Psychology'] | 3,805,437 | [['M01.060.057'], ['M01.060.116'], ['F01.752.747.189', 'F02.739.794.206'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['N01.824.547'], ['I01.738'], ['F02.880', 'K01.844.664']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Tramadol for postoperative shivering: a double-blind comparison with pethidine. | In most operating and recovery rooms, shivering is controlled by the use of humidifiers, warming blankets, and inhalation of humidified heated oxygen. However, pharmacological control is an effective alternate treatment modality. This randomized, double-blind trial, conducted in 30 ASA Grade 1 or 2 patients, was design... | ['Adult', 'Analgesics, Opioid', 'Anesthesia', 'Anesthesia Recovery Period', 'Blood Pressure', 'Body Temperature', 'Double-Blind Method', 'Female', 'Humans', 'Injections, Intravenous', 'Male', 'Meperidine', 'Middle Aged', 'Norepinephrine', 'Postoperative Complications', 'Prospective Studies', 'Pulse', 'Serotonin Uptake ... | 11,314,834 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E03.155'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.374', 'G07.110'], ['E05.318.370.300', 'E05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthetic approaches and biological evaluation of some new sulfonate ester-containing quinazoline derivatives as potentially active antimicrobial agents. | Several sulfonate ester-containing quinazolinone derivatives that are substituted with, isolated or fused, aryl, hetaryl or hetarylphenyl ring systems were synthesized with a view to evaluate their efficacy as new bactericidal and/or fungicidal agents. Synthesis of these products involved prior preparation of the 2-[4'... | ['4-Quinolones', 'Anti-Infective Agents', 'Bacteria', 'Fungi', 'Microbial Sensitivity Tests', 'Sulfonic Acids'] | 7,605,606 | [['D03.633.100.810.835.830'], ['D27.505.954.122'], ['B03'], ['B01.300'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D01.029.260.877.740', 'D01.875.800.740', 'D02.886.645.600']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A validation study of the Facial-Oral Tract Therapy Swallowing Assessment of Saliva. | OBJECTIVE: To investigate the validity and reliability of the Swallowing Assessment of Saliva in detection of aspiration risk.DESIGN: Validation study.SETTING: Inpatient neurorehabilitation centre.SUBJECTS: Adult patients with acquired brain injury. A total of 43 patients for concurrent validity and 33 other patients f... | ['Aged', 'Brain Injuries', 'Deglutition', 'Deglutition Disorders', 'Female', 'Humans', 'Male', 'Middle Aged', 'Rehabilitation', 'Reproducibility of Results', 'Saliva'] | 25,920,675 | [['M01.060.116.100'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G10.261.178'], ['C06.405.117.119', 'C09.775.174'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.169.063.500', 'E02.831', 'H02.403.680.600', 'N02.421.784'], ['E05.318.370.725', 'E05.337.851', 'N05.715.36... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Mapping fires and American Red Cross aid using demographic indicators of vulnerability. | Social vulnerability indicators can assist with informing disaster relief preparation. Certain demographic segments of a population may suffer disproportionately during disaster events, and a geographical understanding of them can help to determine where to place strategically logistical assets and to target disaster-a... | ['Demography', 'Disasters', 'Fires', 'Humans', 'Los Angeles', 'Red Cross', 'Relief Work', 'Risk Assessment', 'Vulnerable Populations'] | 27,170,545 | [['I01.240', 'N01.224', 'N06.850.505.400'], ['N06.230.100'], ['N06.230.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.580.200.450', 'Z01.107.567.875.760.200.450', 'Z01.433.565'], ['N03.540.514.642', 'N03.540.630.780.608'], ['I01.880.787.839', 'N06.230.100.300'], ['E05.318.740.600.800.715', 'N... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Regulation of gap junctional communication by astrocytic mitochondrial K(ATP) channels following neurotoxin administration in in vitro and in vivo models. | It is known that neuronal ATP-sensitive potassium (K(ATP)) channels and astrocytic gap junctions (GJs) are involved in the mechanism underlying neurodisorders. The K(ATP) channels exist also in glial cells, and the objective of this study was to determine whether the astrocytic K(ATP) channels exert their effect on neu... | ['Animals', 'Astrocytes', 'Cell Communication', 'Cells, Cultured', 'Gap Junctions', 'Male', 'Neurons', 'Potassium Channels', 'Rats', 'Rats, Sprague-Dawley'] | 21,474,909 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['G04.085'], ['A11.251'], ['A11.284.149.165.420.471'], ['A08.675', 'A11.671'], ['D12.776.157.530.400.600', 'D12.776.543.550.450.750', 'D12.776.543.585.400.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sleep, memory, and learning in off-pump coronary artery bypass patients. | In this study, I examined sleep, memory, and learning in off-pump coronary artery bypass (OPCAB) patients. Sixty-six men and women aged >or=60 years wore actigraphs to record sleep and completed sleep diaries for two 24-hour periods following OPCAB surgery. Prior to discharge from the hospital, participants completed t... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Coronary Artery Bypass, Off-Pump', 'Female', 'Humans', 'Learning', 'Male', 'Memory', 'Middle Aged', 'Postoperative Period', 'Sleep'] | 16,287,055 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.520.220.189'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540'], ['M01.060.116.630'], ['E04.614.750', 'N02.42... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Intestinal capillariasis as a cause of chronic diarrhoea in Egypt. | Intestinal capillariasis in humans is caused by a nematode- Capillaria philippinensis, which infects small fresh water or brackish fish and some fish eating birds. It has occurred in areas where people eat raw fish such as the Philippines and Thailand. This paper reports a case of a women with intestinal capillariasis ... | ['Animals', 'Capillaria', 'Diarrhea', 'Egypt', 'Enoplida Infections', 'Female', 'Humans', 'Intestinal Diseases, Parasitic', 'Middle Aged'] | 9,617,050 | [['B01.050'], ['B01.050.500.500.294.100.275.780.180'], ['C23.888.821.214'], ['Z01.058.266.317'], ['C01.610.335.508.100.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.432', 'C06.405.469.452'], ['M01.060.116.630']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
A general latent class model for performance evaluation of diagnostic tests in the absence of a gold standard: an application to Chagas disease. | We propose a new general Bayesian latent class model for evaluation of the performance of multiple diagnostic tests in situations in which no gold standard test exists based on a computationally intensive approach. The modeling represents an interesting and suitable alternative to models with complex structures that in... | ['Algorithms', 'Animals', 'Bayes Theorem', 'Chagas Disease', 'Computational Biology', 'Diagnostic Tests, Routine', 'Enzyme-Linked Immunosorbent Assay', 'False Negative Reactions', 'False Positive Reactions', 'Humans', 'Models, Statistical', 'Probability', 'Sensitivity and Specificity', 'Software'] | 22,919,430 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['C01.610.752.300.900.200', 'C01.920.625'], ['H01.158.273.180', 'L01.313.124'], ['E01.370.395'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Theileria parva live vaccination: parasite transmission, persistence and heterologous challenge in the field. | The 'Muguga cocktail' live vaccine, delivered by an infection and treatment protocol, has been widely deployed in Eastern, Central and Southern Africa to protect cattle against East Coast fever, caused by Theileria parva. The vaccine contains 3 component stocks (Muguga, Serengeti-transformed and Kiambu 5). In a previou... | ['Animals', 'Carrier State', 'Cattle', 'Follow-Up Studies', 'Genotype', 'Protozoan Vaccines', 'Theileria parva', 'Theileriasis', 'Vaccines, Attenuated'] | 17,352,850 | [['B01.050'], ['N06.850.520.169'], ['B01.050.150.900.649.313.500.380.271'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.380'], ['D20.215.894.582'], ['B01.043.075.600.580.700.500'], ['C01.610.701.688.735', 'C01.610.752.625.735', 'C01.610.752.750', 'C01.920.930.915', '... | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The VicGeneration study--a birth cohort to examine the environmental, behavioural and biological predictors of early childhood caries: background, aims and methods. | BACKGROUND: Dental caries (decay) during childhood is largely preventable however it remains a significant and costly public health concern, identified as the most prevalent chronic disease of childhood. Caries in children aged less than five years (early childhood caries) is a rapid and progressive disease that can be... | ['Australia', 'Cohort Studies', 'DMF Index', 'Dental Care for Children', 'Dental Caries', 'Disease Progression', 'Female', 'Health Behavior', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Prevalence', 'Risk Factors', 'Saliva', 'Social Environment'] | 20,181,292 | [['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.308.980.438.300.350', 'E06.208.266', 'N05.715.360.300.800.438.300.340', 'N06.850.520.308.980.438.300.350', 'N06.890.160.100'], ['E06.170.152', 'N02.421.240.190.215'], ['C07.793.720.210'], ['C23.... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Periodontal changes in liver cirrhosis and post-transplantation patients. I: clinical findings. | BACKGROUND: Cyclosporin A (CsA) is widely used to prevent liver transplantation failure. CsA-induced gingival overgrowth is a common side effect. However, the effect of cirrhotic liver disease, liver transplantation, and immunosuppressive therapy on the periodontium is yet unclear. The aim of the present cross-sectiona... | ['Analysis of Variance', 'Cyclosporine', 'Female', 'Gingival Hyperplasia', 'Humans', 'Immunosuppressive Agents', 'Liver Cirrhosis', 'Liver Transplantation', 'Male', 'Middle Aged', 'Statistics, Nonparametric', 'Tacrolimus'] | 11,577,956 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['C07.465.714.258.428.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['C06.552.630', 'C23.550.355.412'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.93... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular phylogenetics and morphological evolution of St. John's wort (Hypericum; Hypericaceae). | Phylogenetic hypotheses for the large cosmopolitan genus Hypericum (St. John's wort) have previously been based on morphology, and molecular studies have thus far included only a few species. In this study, we used 360 sequences of the internal transcribed spacer (ITS) region of nuclear ribosomal DNA (nrDNA) for 206 sp... | ['Africa', 'Bayes Theorem', 'Biological Evolution', 'DNA, Plant', 'DNA, Ribosomal Spacer', 'Hypericum', 'Molecular Sequence Data', 'Phylogeny', 'Sequence Analysis, DNA', 'South America'] | 23,058,779 | [['Z01.058'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G05.045', 'G16.075'], ['D13.444.308.435'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['B01.650.940.800.575.912.250.859.625.500'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700'], ['Z0... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Lutzomyia longipalpis spatial distribution and association with environmental variables in an urban focus of visceral leishmaniasis, Misiones, Argentina. | This study describes the spatial distribution pattern of Lu. longipalpis abundance in Posadas-Garup?, Argentina, where four cases of human Visceral Leishmaniasis had been recorded. A total of 2428 Lu. longipalpis were captured in 42% of the 305 sites sampled with CDC light traps, its abundance shows spatial autocorrela... | ['Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Argentina', 'Chickens', 'Child', 'Child, Preschool', 'Disease Vectors', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Leishmaniasis, Visceral', 'Male', 'Plants', 'Psychodidae', 'Urban Population', 'Young Adult'] | 20,096,256 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['Z01.107.757.077'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.335.188', 'N06.850.520.203.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The association of low-molecular-weight hydrophobic compounds with native casein micelles in bovine milk. | The agreed biological function of the casein micelles in milk is to carry minerals (calcium, magnesium, and phosphorus) from mother to young along with amino acids for growth and development. Recently, native and modified casein micelles were used as encapsulating and delivery agents for various hydrophobic low-molecul... | ['Animals', 'Caseins', 'Chromatography, Liquid', 'Hydrophobic and Hydrophilic Interactions', 'Mass Spectrometry', 'Micelles', 'Milk', 'Milk Proteins', 'Molecular Weight', 'Phospholipids'] | 26,074,238 | [['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['E05.196.181.400'], ['G02.409'], ['E05.196.566'], ['D05.374', 'D26.255.560'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['A12.790.520', 'D12.776.256.159.750', 'G07.203.300.428.159.812', 'J02.500.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Long-term outcome of prismatic correction in children with consecutive esotropia after bilateral lateral rectus recession. | AIMS: To determine the long-term outcome of prismatic correction in consecutive esotropia after bilateral lateral rectus (BLR) recession in children.METHODS: Of 392 children with exotropia who received BLR recession, 44 developed consecutive esotropia. Five children underwent reoperation and 39 were treated with base-o... | ['Age of Onset', 'Child', 'Child, Preschool', 'Depth Perception', 'Esotropia', 'Exotropia', 'Eyeglasses', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Oculomotor Muscles', 'Ophthalmologic Surgical Procedures', 'Treatment Outcome', 'Vision, Binocular'] | 25,336,581 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.406'], ['M01.060.406.448'], ['F02.463.593.200', 'F02.463.593.778.255'], ['C10.292.562.887.300', 'C11.590.810.400'], ['C10.292.562.887.650', 'C11.590.810.440'], ['E07.632.500.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.... | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transport properties of merodiploids covering the dagA locus in Escherichia coli K-12. | A membrane componenet of the dag transport system which serves for glycine, D-alanine, and D-serine is coded for by the dagA gene at minute 83 of the Escherichia coli chromosome. Merodiploid strains (dagA+/dagA+) show two to three times the transport activity for only those amino acids that are substrates of the dag tr... | ['Alanine', 'Biological Transport, Active', 'Cell Membrane', 'Diploidy', 'Escherichia coli', 'Genes', 'Glycerol', 'Glycine', 'Kinetics', 'Leucine', 'Mutation', 'Proline', 'Serine', 'Stereoisomerism'] | 1,097,389 | [['D12.125.042'], ['G03.143.310'], ['A11.284.149'], ['G05.700.264'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D12.125.481'], ['G01.374.661', 'G02.111.490'], ['D12.125.070.637', 'D12.125.142.441'], ['G05.365.590'], ['D12.125.072.401.62... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Meta-analysis on the epidemiology of Helicobacter pylori infection in China]. | OBJECTIVE: To understand the epidemiologic features and etiology of Helicobacter pylori (H. pylori) infection in China so as to provide evidence for the development of preventive measures on H. pylori infection and related diseases.METHODS: Meta-analysis was used to evaluate the data extracted from 1990 - 2002 publishe... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'China', 'Family', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Stomach Neoplasms'] | 12,848,905 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['F01.829.263', 'I01.880.853.150'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Liver lobe-based magnetic resonance diffusion-weighted imaging using multiple b values in patients with hepatitis B-related liver cirrhosis: association with the liver disease severity according to the Child-Pugh class. | OBJECTIVE: To determine the associations of liver lobe-based magnetic resonance diffusion-weighted imaging findings using multiple b values with the presence and Child-Pugh class of cirrhosis in patients with hepatitis B.METHODS: Seventy-four cirrhotic patients with hepatitis B and 25 healthy volunteers underwent diffu... | ['Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Hepatitis B', 'Humans', 'Liver Cirrhosis', 'Liver Diseases', 'Male', 'Middle Aged', 'Prospective Studies', 'Young Adult'] | 26,222,818 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.350.825.500.150'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Studies on Ostertagia spp. from Greenlandic sheep: arrested development and worm length. | Studies were conducted to investigate earlier observations that lambs slaughtered in Greenland in late September/early October have relatively few arrested larvae in the abomasal mucosa and that the adult Ostertagia from such lambs are abnormally large. Post mortem examination of naturally infected ewes in mid-winter d... | ['Abomasum', 'Animals', 'Female', 'Greenland', 'Male', 'Ostertagia', 'Ostertagiasis', 'Sheep', 'Sheep Diseases', 'United Kingdom'] | 2,080,777 | [['A13.869.106'], ['B01.050'], ['Z01.107.567.403', 'Z01.542.816.124.500', 'Z01.639.400'], ['B01.050.500.500.294.400.968.746.432'], ['C01.610.335.508.700.775.825.580'], ['B01.050.150.900.649.313.500.380.791'], ['C22.836'], ['Z01.542.363']] | ['Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Firefly bioluminescent assay of ATP in the presence of ATP extractant by using liposomes. | Liposomes containing phosphatidylcholine (PC) and cholesterol (Chol) were applied to the enhancer for firefly bioluminescence (BL) assay for ATP in the presence of cationic surfactants using as an extractant for the release of ATP from living cells. Benzalkonium chloride (BAC) was used as an ATP extractant. However, BA... | ['Adenosine Triphosphate', 'Animals', 'Benzalkonium Compounds', 'Biological Assay', 'Cholesterol', 'Detergents', 'Escherichia coli', 'Fireflies', 'Liposomes', 'Luciferases, Firefly', 'Luminescent Agents', 'Luminescent Measurements', 'Phosphatidylcholines'] | 16,383,346 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D02.092.877.096.040', 'D02.675.276.080'], ['E05.091'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D27.720.877.265', 'J01.516.381'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
ProSeal versus the Classic laryngeal mask airway for positive pressure ventilation during laparoscopic cholecystectomy. | BACKGROUND: We tested the hypothesis that the ProSeal laryngeal mask airway (PLMA) is a more effective ventilatory device than the Classic laryngeal mask airway (LMA) for laparoscopic cholecystectomy.METHODS: Eighty anaesthetized, paralyzed patients (ASA 1-2, aged 18-80 yr) were randomly allocated for airway management... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Air Pressure', 'Cholecystectomy, Laparoscopic', 'Equipment Design', 'Female', 'Humans', 'Laryngeal Masks', 'Male', 'Middle Aged', 'Pneumoperitoneum, Artificial', 'Positive-Pressure Respiration'] | 12,173,201 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G16.500.750.274.100', 'N06.230.300.100.185.100'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500.475', 'E02.585.578.475', 'E05.497.578.475', 'E07.700.500.450', ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Thoracoscopic lung volume reduction surgery for pulmonary emphysema patients with severe hypercapnia. | OBJECTIVES: We assessed whether hypercapnia patients with an extremely high level of PaCO2 > or = 60 mmHg were suitable candidates for lung volume reduction in the treatment of severe pulmonary emphysema.METHODS: Of 65 patients undergoing lung volume reduction surgery between May 1993 and August 1997, 6 (9.23%) who had... | ['Aged', 'Carbon Dioxide', 'Female', 'Follow-Up Studies', 'Forced Expiratory Volume', 'Humans', 'Hypercapnia', 'Male', 'Middle Aged', 'Partial Pressure', 'Pneumonectomy', 'Pulmonary Emphysema', 'Thoracic Surgery, Video-Assisted'] | 11,552,273 | [['M01.060.116.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['M01.060.116.630'], ['G01.374.715.714... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Yeast two-hybrid interactions between Arabidopsis lyrata S Receptor Kinase and the ARC1 E3 ligase. | Here we describe protein-protein interactions between signaling components in the conserved self-incompatibility pathway from Brassica spp. and Arabidopsis lyrata. Previously, we had demonstrated that ARC1 is necessary in A. lyrata for the rejection of self-pollen by the self-incompatibility pathway. The results descri... | ['Arabidopsis', 'Arabidopsis Proteins', 'Protein Binding', 'Protein Kinases', 'Two-Hybrid System Techniques', 'Ubiquitin-Protein Ligases'] | 27,175,603 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.679', 'G03.808'], ['D08.811.913.696.620.682'], ['E05.393.220.870', 'E05.601.690.650', 'E05.601.870'], ['D08.811.464.938.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of streaming potential on the transport and separation of charged spherical solutes in nanochannels subjected to particle-wall interactions. | In this work, we theoretically investigate the implications of streaming potential on the transport and size-based separation of charged solutes in nanoscale confinements. By employing a regular perturbation analysis, we demonstrate that the consideration of streaming potential establishes a new paradigm of size-based ... | ['Adsorption', 'Electrochemistry', 'Microfluidics', 'Microscopy, Atomic Force', 'Models, Chemical', 'Models, Statistical', 'Nanoparticles', 'Nanotechnology', 'Osmosis', 'Particle Size', 'Pressure', 'Solutions', 'Surface Properties', 'Temperature', 'Time Factors'] | 19,618,905 | [['G01.030', 'G02.020'], ['H01.181.529.307'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['E05.599.495'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['J01.637.512.600'], ['H01.603', 'J01.897.520.600'], ['G01.154.090.7... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Mutation of N-linked glycosylation in EpCAM affected cell adhesion in breast cancer cells. | Epithelial cell adhesion molecule (EpCAM) expression is elevated in breast cancer tissue, and correlates with the cancer metastasis and cell adhesion. Although EpCAM glycosylation is supposed to be associated with its function, the contribution of N-glycosylation to its function remains unclear. Here we analyzed cell a... | ['Breast Neoplasms', 'Cell Adhesion', 'Epithelial Cell Adhesion Molecule', 'Female', 'Glycosylation', 'Humans', 'Mutation', 'Tumor Cells, Cultured'] | 28,315,854 | [['C04.588.180', 'C17.800.090.500'], ['G04.022'], ['D12.776.395.550.200.263', 'D12.776.543.550.200.263', 'D23.050.285.357', 'D23.050.301.350.263'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['A11.251.860']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of PM2.5 in Guangzhou, China: uses of organic markers for supporting source apportionment. | Organic carbon (OC), elemental carbon (EC), and non-polar organic compounds including n-alkanes (n-C14-n-C40), polycyclic aromatic hydrocarbons (PAHs), phthalate esters (PAEs) and hopanes were quantified in fine particulate (PM2.5), which were collected in urban area of Guangzhou, China in winter and summer in 2012/201... | ['Air Pollutants', 'China', 'Dibutyl Phthalate', 'Environmental Monitoring', 'Particulate Matter', 'Polycyclic Aromatic Hydrocarbons', 'Seasons', 'Vehicle Emissions'] | 26,851,882 | [['D27.888.284.101'], ['Z01.252.474.164'], ['D02.241.223.805.225'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D20.633'], ['D02.455.426.559.847', 'D04.615'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['D20.832']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Salivary antibody levels in adolescents in response to a meningococcal serogroup C conjugate booster vaccination nine years after priming: systemically induced local immunity and saliva as potential surveillance tool. | BACKGROUND: In several countries large-scale immunization of children and young adults with Meningococcal serogroup C (MenC) conjugate vaccines has induced long-standing herd protection. Salivary antibodies may play an important role in mucosal protection against meningococcal acquisition and carriage.AIM: To investiga... | ['Adolescent', 'Antibodies, Bacterial', 'Child', 'Child, Preschool', 'Epidemiological Monitoring', 'Female', 'Humans', 'Immunization, Secondary', 'Immunoglobulin A', 'Immunoglobulin G', 'Infant', 'Male', 'Meningococcal Vaccines', 'Neisseria meningitidis, Serogroup C', 'Saliva', 'Serum', 'Vaccines, Conjugate'] | 26,100,925 | [['M01.060.057'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.375', 'N06.850.520.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.485', 'E05.478.550.550'], ['D12.776.124.486.485.114.619.026', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Automated analytical standard production with supercritical fluid chromatography for the quantification of bioactive C17-polyacetylenes: a case study on food processing waste. | Food processing enterprises produce enormous amounts of organic waste that contains valuable phytochemicals (e.g. C17-polyacetylenes). Knowledge on the phytochemicals content is a first step towards valorisation. Quantification of C17-polyacetylenes is however often hampered by the lack of commercially available standa... | ['Chromatography, Liquid', 'Chromatography, Supercritical Fluid', 'Food Handling', 'Mass Spectrometry', 'Polyynes'] | 25,038,689 | [['E05.196.181.400'], ['E05.196.181.750'], ['J01.576.423.200'], ['E05.196.566'], ['D02.455.326.397.680']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1 | Inspired by VUF6884 (7-Chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine), reported as a dual H1/H4 receptor ligand (pKi: 8.11 (human H1R (hH1R)), 7.55 (human H4R (hH4R))), four known and 28 new oxazepine and related oxepine derivatives were synthesised and pharmacologically characterized at histamine recept... | ['Animals', 'Cells, Cultured', 'Chlorine', 'Guinea Pigs', 'Humans', 'Oxazepines', 'Oxepins', 'Protein Binding', 'Receptor, Serotonin, 5-HT2A', 'Receptors, G-Protein-Coupled', 'Receptors, Histamine H1', 'Receptors, Histamine H4', 'Sf9 Cells', 'Structure-Activity Relationship'] | 27,697,645 | [['B01.050'], ['A11.251'], ['D01.268.380.150', 'D01.362.225'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.066.498'], ['D02.355.291.852', 'D03.383.564'], ['G02.111.679', 'G03.808'], ['D12.776.543.750.670.800.200.100', 'D12.776.543.750.695.800.200.100', 'D12.776.543.75... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurologic Outcomes After Low-Volume, Ultrasound-Guided Interscalene Block and Ambulatory Shoulder Surgery. | BACKGROUND AND OBJECTIVES: Postoperative neurologic symptoms after interscalene block and shoulder surgery have been reported to be relatively frequent. Reports of such symptoms after ultrasound-guided block have been variable. We evaluated 300 patients for neurologic symptoms after low-volume, ultrasound-guided inters... | ['Adult', 'Aged', 'Ambulatory Surgical Procedures', 'Anesthetics, Combined', 'Anesthetics, Local', 'Arthroscopy', 'Bupivacaine', 'Electric Stimulation', 'Female', 'Humans', 'Male', 'Mepivacaine', 'Middle Aged', 'Nerve Block', 'Neurologic Examination', 'Peripheral Nervous System Diseases', 'Prospective Studies', 'Should... | 27,281,729 | [['M01.060.116'], ['M01.060.116.100'], ['E04.030'], ['D27.505.696.277.100.017', 'D27.505.954.427.210.100.017'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['D02.065.199.239', 'D02.092.146.113.239'], ['E05.723.402'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An integrated strategy of knowledge application for optimal e-health implementation: a multi-method study protocol. | BACKGROUND: E-health is increasingly valued for supporting: 1) access to quality health care services for all citizens; 2) information flow and exchange; 3) integrated health care services and 4) interprofessional collaboration. Nevertheless, several questions remain on the factors allowing an optimal integration of e-... | ['Decision Support Techniques', 'Humans', 'Internet', 'Knowledge', 'Medical Records Systems, Computerized', 'Multivariate Analysis', 'Organizational Policy', 'Planning Techniques', 'Quebec', 'Telemedicine'] | 18,435,853 | [['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['K01.468'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Humanities [K]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Association between second-generation antipsychotic medication half-life and hospitalization in the community treatment of adult schizophrenia. | OBJECTIVE: To examine the effect of antipsychotic medication half-life on the risk of psychiatric hospital admission and emergency department (ED) visits among adults with schizophrenia.METHODS: Retrospective claims-based cohort study of adult Medicaid patients with schizophrenia who were prescribed second-generation a... | ['Adult', 'Antipsychotic Agents', 'Cohort Studies', 'Emergency Service, Hospital', 'Female', 'Half-Life', 'Hospitalization', 'Humans', 'Insurance Claim Review', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Retrospective Studies', 'Risk Assessment', 'Risperidone', 'Schizophrenia', 'United States'] | 21,991,926 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['G01.910.405'], ['E02.760.400', 'N02.421.585.400'], ['B0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Global Coronary Artery Plaque Area is Associated with Myocardial Hypoperfusion in Women with Non-ST Elevation Myocardial Infarction. | BACKGROUND: Women with non-ST elevation myocardial infarction (NSTEMI) have similar extent of myocardial ischemia but less obstructive coronary artery disease (CAD) than their male counterparts. We tested the impact of global coronary artery plaque area and artery tortuosity on myocardial perfusion in NSTEMI patients.M... | ['Aged', 'Aged, 80 and over', 'Coronary Angiography', 'Coronary Artery Disease', 'Coronary Stenosis', 'Echocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Myocardial Infarction', 'Myocardial Ischemia', 'Odds Ratio', 'Prospective Studies', 'Risk Assessment', 'Sex Distribution'] | 25,692,527 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Is the zona pellucida an intrinsic source of signals activating maternal recognition of the developing mammalian embryo? | Mammalian mothers undergoing embryo implantation must specifically recognize the developing embryo in a species-restricted manner. We previously observed that immune cells derived from early pregnant mice could promote endometrial differentiation and embryo implantation in blastocyst-transferred pseudopregnant mice. Al... | ['Animals', 'Cell Communication', 'Egg Proteins', 'Embryo, Mammalian', 'Female', 'Fertilization', 'Fetal Development', 'Immunity, Cellular', 'Male', 'Membrane Glycoproteins', 'Mice', 'Models, Immunological', 'Pregnancy', 'Pregnancy Proteins', 'Protein Binding', 'Receptors, Cell Surface', 'Species Specificity', 'Spermat... | 19,523,688 | [['B01.050'], ['G04.085'], ['D12.776.290'], ['A16.254'], ['G08.686.784.277'], ['G07.345.500.325.235', 'G08.686.784.170.157'], ['G12.450.050.400'], ['D12.776.395.550', 'D12.776.543.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395.500'], ['G08.686.784.769'], ['D12.776.780'], ['G02.111.679', 'G03.808'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[An experimental study of Karnovsky's stain for differentiating motor and sensory funiculi during peripheral nerve surgery]. | For the clinical application of funicular suture of the served peripheral nerve, it is mandatory to differentiate motor and sensory dominant funiculi. The author investigated whether Karnovsky's stain could be simplified to make this technique applicable during surgery. This stain was shown to be definitively applicabl... | ['Animals', 'Dogs', 'Humans', 'Peripheral Nerves', 'Rats', 'Staining and Labeling', 'Suture Techniques'] | 2,470,845 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800'], ['B01.050.150.900.649.313.992.635.505.700'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670'], ['E04.987.775']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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