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N-terminal and C-terminal heparin-binding domain polypeptides derived from fibronectin reduce adhesion and invasion of liver cancer cells. | BACKGROUND: Fibronectin (FN) is known to be a large multifunction glycoprotein with binding sites for many substances, including N-terminal and C-terminal heparin-binding domains. We investigated the effects of highly purified rhFNHN29 and rhFNHC36 polypeptides originally cloned from the two heparin-binding domains on ... | ['Animals', 'Carcinoma, Hepatocellular', 'Cell Adhesion', 'Cell Line, Tumor', 'Collagen', 'Drug Combinations', 'Fibronectins', 'Glycoproteins', 'Heparin', 'Humans', 'Laminin', 'Liver Neoplasms', 'Male', 'Mice', 'Mice, Nude', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Peptides', 'Protein Structure, Tertiary', 'Pro... | 20,939,933 | [['B01.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.022'], ['A11.251.210.190', 'A11.251.860.180'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D26.310'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D09.400.43... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Algorithms and complexity of enumerating minimal precursor sets in genome-wide metabolic networks. | MOTIVATION: In the context of studying whole metabolic networks and their interaction with the environment, the following question arises: given a set of target metabolites T and a set of possible external source metabolites , which are the minimal subsets of that are able to produce all the metabolites in T. Such s... | ['Algorithms', 'Computational Biology', 'Metabolic Networks and Pathways', 'Models, Theoretical'] | 22,782,547 | [['G17.035', 'L01.224.050'], ['H01.158.273.180', 'L01.313.124'], ['G03.493'], ['E05.599']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of skin concentrations following topical versus oral corticosteroid treatment: reconsidering the treatment of common inflammatory dermatoses. | BACKGROUND: Topical corticosteroids are often considered to have greater safety and poorer efficacy than oral corticosteroids in treating psoriasis and atopic dermatitis. There are limited data for assessing relative efficacy of topical and systemic corticosteroids, however. The concentration of corticosteroid in skin,... | ['Administration, Cutaneous', 'Administration, Oral', 'Adrenal Cortex Hormones', 'Dermatitis', 'Humans', 'Skin'] | 20,027,934 | [['E02.319.267.120.060'], ['E02.319.267.100'], ['D06.472.040'], ['C17.800.174'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A17.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Caffeic acid phenethyl ester suppresses oxidative stress in 3T3-L1 adipocytes. | The generation of oxidative stress, characterized by enhanced reactive oxygen species (ROS) formation, has been found in obesity. ROS production was increased during the differentiation of 3T3-L1 cells into adipocytes. We previously reported that caffeic acid phenethyl ester (CAPE) suppresses 3T3-L1 differentiation to ... | ['3T3-L1 Cells', 'Adipocytes', 'Animals', 'Caffeic Acids', 'Mice', 'Molecular Structure', 'Oxidative Stress', 'PPAR gamma', 'Phenylethyl Alcohol', 'RNA, Messenger', 'Reactive Oxygen Species', 'Superoxide Dismutase'] | 23,927,014 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['B01.050'], ['D02.241.223.200.054'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.111.570', 'G02.466'], ['G03.673', 'G07.775.750'], ['D12.776.826.239.588'], ['D02.033.375.650'], ['D13.444.735.544'], ['D01.339.431', 'D01.650.775'], ['D08.81... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Susceptibility-weighted MRI of endometrioma: preliminary results. | OBJECTIVE: Susceptibility-weighted MRI combines magnitude and phase information from fully velocity-compensated gradient-echo sequences and depicts as signal voids the susceptibility effects caused by local inhomogeneity of the magnetic field. Our objective, based on MRI of 60 pathologically proven ovarian cystic lesio... | ['Adult', 'Aged', 'Algorithms', 'Endometriosis', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Middle Aged', 'Pilot Projects', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 18,941,070 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effect of gamma rays on efficiency of gene transfer in DNA repair-proficient and -deficient cell lines. | Ionizing radiation induces a number of molecular changes in cells, including DNA damage, mutation, genetic recombination, gene amplification, and chromosomal rearrangement. The studies described here make use of the process of DNA-mediated gene transfer to examine the molecular effects of ionizing radiation. Two Chines... | ['Animals', 'Cell Line', 'Cricetinae', 'DNA Damage', 'DNA Repair', 'Gamma Rays', 'Gene Expression Regulation', 'Plasmids', 'Transfection', 'Transformation, Genetic'] | 3,194,800 | [['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['G05.200'], ['G02.111.222', 'G05.219'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['G05.308'], ['G05.360.600'], ['E05.393.350.810', 'G05.728.860'], ['G05.728.865']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prediction of Freezing of Gait in Parkinson's From Physiological Wearables: An Exploratory Study. | Freezing of gait (FoG) is a common gait impairment among patients with advanced Parkinson's disease. FoG is associated with falls and negatively impacts the patient's quality of life. Wearable systems that detect FoG in real time have been developed to help patients resume walking by means of rhythmic cueing. Current m... | ['Aged', 'Aged, 80 and over', 'Electrocardiography, Ambulatory', 'Equipment Design', 'Gait', 'Galvanic Skin Response', 'Humans', 'Middle Aged', 'Models, Statistical', 'Monitoring, Ambulatory', 'Parkinson Disease', 'Signal Processing, Computer-Assisted'] | 26,259,206 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['E05.320'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Trypsin-like serine proteinase action: determination of the catalytic parameters KS, k+2 and k/3 under conditions where the substrate exceeds the enzyme concentration. | A method for the determination of the catalytic parameters Ks, k+2 and k+3 describing trypsin-like serine proteinase action has been developed from the quantitative analysis of the kinetics of hydrolysis of two specific chromogenic substrates, N-alpha-carbobenzoxy-L-arginine p-nitrophenyl ester and N-alpha-carbobenzoxy... | ['Animals', 'Catalysis', 'In Vitro Techniques', 'Kallikreins', 'Kinetics', 'Serine Endopeptidases', 'Trypsin', 'Urokinase-Type Plasminogen Activator'] | 2,790,064 | [['B01.050'], ['G02.130'], ['E05.481'], ['D08.811.277.656.300.760.442', 'D08.811.277.656.959.350.442', 'D12.776.124.125.597', 'D23.119.597'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.656.300.760', 'D08.811.277.656.959.350'], ['D08.811.277.656.300.760.895', 'D08.811.277.656.959.350.895'], ['D08.811.277.656.300.760.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380. | The novel compound 5-iodo-A-85380 binds with higher affinity to alpha4beta2* nicotinic acetylcholine receptors (nAChR), compared with other nAChR subtypes (Mukhin et al., 2000). In the present study, we have confirmed that in competition binding assays for three major nAChR subtypes, 5-iodo-A-85380 is 850 and 27,000-fo... | ['Acetylcholine', 'Animals', 'Azetidines', 'Binding, Competitive', 'Calcium', 'Cell Line', 'Dopamine', 'Fibroblasts', 'Fluorometry', 'Indicators and Reagents', 'Mice', 'Neostriatum', 'Nicotinic Agonists', 'Nicotinic Antagonists', 'Norepinephrine', 'Pyridines', 'Radioligand Assay', 'Rats', 'Rats, Sprague-Dawley', 'Recep... | 15,527,819 | [['D02.092.211.111'], ['B01.050'], ['D03.383.082.301'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['A11.329.228'], ['E05.196.712.516.600'], ['D27.720.47... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) in two Mexican brothers harboring a novel mutation in the ECGF1 gene. | Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive disease caused by mutations in the thymidine phosphorylase gene located on chromosome 22q13.32-ter, causing defective functioning of the enzyme. At present 87 sporadic or familial cases have been reported and 52 different mutati... | ['Adult', 'Female', 'Humans', 'Male', 'Mexico', 'Mitochondrial Encephalomyopathies', 'Mutation', 'Pedigree', 'Thymidine Phosphorylase'] | 18,280,229 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.589'], ['C05.651.460.620', 'C10.228.140.163.540', 'C10.668.491.500.500', 'C18.452.132.540', 'C18.452.660.560.620'], ['G05.365.590'], ['E05.393.673'], ['D08.811.913.400.725.850.500', 'D23.050.301.500.600.925', 'D23.050.705.552.600.850']] | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
miRNAs induced by white spot syndrome virus involve in immunity pathways in shrimp Litopenaeus vannamei. | White shrimp Litopenaeus vannamei are widely cultured in the world and white spot syndrome virus (WSSV) led to huge economic losses in the shrimp industry every year. In the present study, miRNAs involved in the response of shrimp L. vannamei to WSSV infection were obtained through the Illumina HiSeq 2500 high-throughp... | ['Animals', 'Immunity, Innate', 'MicroRNAs', 'Penaeidae', 'White spot syndrome virus 1'] | 31,408,731 | [['B01.050'], ['G12.450.564'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['B01.050.500.131.365.190.660'], ['B04.280.505.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The application of a plasmid DNA encoding IFN-alpha 1 postinfection enhances cumulative survival of herpes simplex virus type 2 vaginally infected mice. | Using a hormonally induced susceptibility mouse model to investigate vaginal HSV type 2 (HSV-2) infection, a study was undertaken to determine the efficacy of a plasmid DNA encoding IFN-alpha1 introduced into the vaginal lumen postinfection (PI). Mice infected with HSV-2 intravaginally and treated intravaginally 24 h l... | ['Acute Disease', 'Administration, Intravaginal', 'Animals', 'Antiviral Agents', 'Chlorocebus aethiops', 'Cytotoxicity, Immunologic', 'DNA, Viral', 'Female', 'Gene Expression Regulation', 'Genes, Reporter', 'Herpes Genitalis', 'Herpes Simplex Virus Vaccines', 'Herpesvirus 2, Human', 'Immunity, Cellular', 'Immunization ... | 11,160,227 | [['C23.550.291.125'], ['E02.319.267.120.500'], ['B01.050'], ['D27.505.954.122.388'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['G12.287'], ['D13.444.308.568'], ['G05.308'], ['G05.360.340.024.340.435'], ['C01.221.812.640.350', 'C01.778.640.350', 'C01.925.256.466.382.290', 'C01.925.813.350', 'C12.294.329'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Detection and treatment of Candida auris in an outbreak situation: risk factors for developing colonization and candidemia by this new species in critically ill patients. | BACKGROUND: Candida auris is an emerging, multidrug-resistant yeast causing hospital outbreaks. This study describes the first 24 months of the ongoing C. auris outbreak in our hospital and analyzes predisposing factors to C. auris candidemia/colonization.RESEARCH DESIGN AND METHODS: A 12-month prospective, case-contro... | ['Adult', 'Aged', 'Antifungal Agents', 'Candida', 'Candidemia', 'Case-Control Studies', 'Critical Illness', 'Disease Outbreaks', 'Drug Resistance, Viral', 'Female', 'Fluconazole', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Prospective Studies', 'Risk Factors', 'Voriconazole'] | 30,922,129 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.136'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['C01.150.703.160.175.500', 'C01.150.703.492.500.500', 'C01.757.360.150', 'C23.550.470.790.500.360.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.55... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy of the oral chemoattractant receptor homologous molecule on TH2 cells antagonist BI 671800 in patients with seasonal allergic rhinitis. | BACKGROUND: The inflammatory response in patients with seasonal allergic rhinitis (SAR) is partly mediated by the prostaglandin D2 receptor chemoattractant receptor homologous molecule on T(H)2 cells (CRTH2).OBJECTIVE: We sought to investigate the efficacy and safety of the oral CRTH2 antagonist BI 671800 (50, 200, and... | ['Adult', 'Allergens', 'Anti-Allergic Agents', 'Benzamides', 'Cross-Over Studies', 'Cytokines', 'Double-Blind Method', 'Eosinophils', 'Female', 'Humans', 'Leukocyte Count', 'Male', 'Middle Aged', 'Nasal Mucosa', 'Poaceae', 'Pollen', 'Pyrimidines', 'Receptors, Immunologic', 'Receptors, Prostaglandin', 'Rhinitis, Allergi... | 24,332,218 | [['M01.060.116'], ['D23.050.063'], ['D27.505.954.016'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy and safety of sustained-release oxycodone compared with immediate-release morphine for pain titration in cancer patients: A multicenter, open-label, randomized controlled trial (SOCIAL). | BACKGROUND: The study aims to investigate the effect and safety of sustained-release oxycodone hydrochloride as background dose on pain titration in patients with moderate-to-severe cancer pain.MATERIAL AND METHODS: Adult patients scheduled with a regular strong opioid for cancer-related pain were recruited and randoml... | ['Aged', 'Cancer Pain', 'Delayed-Action Preparations', 'Female', 'Humans', 'Male', 'Middle Aged', 'Morphine', 'Oxycodone', 'Pain Measurement', 'Treatment Outcome'] | 31,192,908 | [['M01.060.116.100'], ['C23.888.592.612.212'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['D03.132.577.249.562.149.575', 'D03.605.497.607.204.650', 'D... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cloning and expression of islandisin, a new thermostable subtilisin from Fervidobacterium islandicum, in Escherichia coli. | A gene encoding a subtilisin-like protease, designated islandisin, from the extremely thermophilic bacterium Fervidobacterium islandicum (DSMZ 5733) was cloned and actively expressed in Escherichia coli. The gene was identified by PCR using degenerated primers based on conserved regions around two of the three catalyti... | ['Amino Acid Sequence', 'Bacteria', 'Base Sequence', 'Cloning, Molecular', 'Enzyme Stability', 'Escherichia coli', 'Hot Temperature', 'Models, Molecular', 'Molecular Sequence Data', 'Phylogeny', 'Sequence Analysis, DNA', 'Subtilisin'] | 16,000,809 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A Stochastic Model for Predicting Age and Mass at Maturity of Insects. | Variation in age and mass at maturity is commonly observed in populations, even among individuals with the same genetic and environmental backgrounds. Accounting for such individual variation with a stochastic model is important for estimating optimal evolutionary strategies and for understanding potential trade-offs a... | ['Aging', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Body Weight', 'Larva', 'Life History Traits', 'Manduca', 'Models, Statistical', 'Stochastic Processes'] | 32,673,092 | [['G07.345.124'], ['G07.203.650.161'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G05.045.513', 'G16.575'], ['B01.050.500.131.617.720.500.500.937.650.525'], ['E05.318.740.500', 'E05.599.8... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Seborrheic dermatitis among Oxford renal transplant recipients. | BACKGROUND: Seborrheic dermatitis is an inflammatory dermatosis with a prevalence of 1-3% in the general population. It is recognized more commonly in those infected by human immunodeficiency virus (HIV). No studies have looked at Seborrheic dermatitis in the context of immunosuppression secondary to organ transplantat... | ['Dermatitis, Seborrheic', 'Female', 'Humans', 'Kidney Transplantation', 'Male', 'Prospective Studies'] | 19,888,944 | [['C17.800.174.580', 'C17.800.794.230', 'C17.800.815.580', 'C17.800.859.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical oversight and the avoidance of repeat induced abortion. | OBJECTIVE: To evaluate the impact of patient counseling, demographics, and contraceptive methods on repeat induced abortion in women attending family planning clinics.METHODS: A retrospective chart review of repeat induced abortions was performed. The analysis included patients with an initial induced abortion obtained... | ['Abortion, Induced', 'Adolescent', 'Adult', 'Contraception', 'Contraceptive Agents', 'Family Planning Services', 'Female', 'Humans', 'New York City', 'Pregnancy', 'Retrospective Studies', 'Young Adult'] | 29,862,496 | [['E04.520.050'], ['M01.060.057'], ['M01.060.116'], ['E02.875.194'], ['D27.505.696.875.360', 'D27.505.954.705.360'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.530.530', 'Z01.107.567.875.500.530.530', 'Z01.433.741'], ['G08.686.784.769'], ['E05.318.372.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Meconium induced IL-8 production and intratracheal albumin alleviated lung injury in newborn pigs. | We have recently shown that albumin added to meconium before intratracheal instillation in newborn pigs limits detrimental effect on the lungs and reduces increase of IL-8. The aim of this study was to test the effect of albumin instillation as rescue treatment in meconium aspiration syndrome (MAS). MAS was induced in ... | ['Albumins', 'Animals', 'Animals, Newborn', 'Blood Chemical Analysis', 'Cattle', 'Hemodynamics', 'Humans', 'Infant, Newborn', 'Interleukin-8', 'Lung', 'Lung Injury', 'Meconium', 'Meconium Aspiration Syndrome', 'Statistics as Topic', 'Swine'] | 15,635,049 | [['D12.776.034'], ['B01.050'], ['B01.050.050.282'], ['E01.370.225.124.100', 'E05.200.124.100'], ['B01.050.150.900.649.313.500.380.271'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D12.776.467.374.200.120.800', 'D12.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of machine learning classifiers for dementia with Lewy bodies using miRNA expression data. | BACKGROUND: Dementia with Lewy bodies (DLB) is the second most common subtype of neurodegenerative dementia in humans following Alzheimer's disease (AD). Present clinical diagnosis of DLB has high specificity and low sensitivity and finding potential biomarkers of prodromal DLB is still challenging. MicroRNAs (miRNAs) ... | ['Aged', 'Biomarkers', 'Case-Control Studies', 'Dementia', 'Female', 'Genetic Association Studies', 'Humans', 'Lewy Body Disease', 'Machine Learning', 'Male', 'MicroRNAs', 'Phosphatidylinositol 3-Kinases', 'Polymorphism, Single Nucleotide', 'Risk', 'Signal Transduction', 'bcl-X Protein'] | 31,666,070 | [['M01.060.116.100'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C10.228.140.380', 'F03.615.400'], ['E05.393.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.079.862.400', 'C10.228.140.380.422', 'C10.228.662.600.200', 'C10.574.928.500', 'F03.615.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Pharmacovigilance database search discloses ClC-K channels as a novel target of the AT1 | BACKGROUND AND PURPOSE: Human ClC-K chloride channels are highly attractive targets for drug discovery as they have a variety of important physiological functions and are associated with genetic disorders. These channels are crucial in the kidney as they control chloride reabsorption and water diuresis. In addition, lo... | ['Angiotensin II Type 1 Receptor Blockers', 'Chloride Channels', 'Databases, Factual', 'Dose-Response Relationship, Drug', 'Humans', 'Imidazoles', 'Molecular Docking Simulation', 'Molecular Structure', 'Pharmacovigilance', 'Structure-Activity Relationship', 'Tetrazoles', 'Valsartan'] | 28,334,417 | [['D27.505.519.162.500'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['E05.599.595.249', 'L01.224.160.249'], ['G02.111... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Differential regulation of prodynophin, c-fos, and serotonin transporter mRNA following withdrawal from a chronic, escalating dose regimen of D-amphetamine. | Several lines of evidence suggest that D-amphetamine (D-AMPH) withdrawal induces a syndrome with symptoms similar to major depressive disorder (MDD). Upregulation of dynorphin (DYN) may underlie the symptoms of MDD and contribute to the negative emotional symptoms associated with psychostimulant withdrawal. Changes in ... | ['Amphetamine', 'Animals', 'Autoradiography', 'Brain', 'Brain Mapping', 'Dose-Response Relationship, Drug', 'Enkephalins', 'Gene Expression Regulation', 'Male', 'Protein Precursors', 'Proto-Oncogene Proteins c-fos', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Serotonin Plasma Membrane Transport Proteins', 'Subst... | 19,116,947 | [['D02.092.471.683.152.110'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['G05.308'], ['D12.776.811'], ['D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of anti-Helicobacter pylori ureB monoclonal antibody on platelet aggregation and activation, and its mechanism study]. | OBJECTIVES: To study the effect of monoclonal antibody (McAb) against helicobacter pylori (Hp) ureB, 1F11 on platelet aggregation and activation, and its mechanism.METHODS: The relativity between human platelet glycoproteins (GPs) and Hp ureB was identified by Western blot and FCM. Platelet aggregation was measured by ... | ['Antibodies, Bacterial', 'Antibodies, Monoclonal', 'Bacterial Proteins', 'Helicobacter pylori', 'Humans', 'Integrin beta3', 'P-Selectin', 'Platelet Activation', 'Platelet Aggregation', 'Urease', 'Urokinase-Type Plasminogen Activator'] | 16,792,917 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.097'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of the protein kinase C inhibitor, staurosporine, on the high dose of methamphetamine-induced behavioral sensitization to dizocilpine (MK-801). | RATIONALE: In our preliminary study, methamphetamine (METH) at 2.5 mg/kg, but not at 1.0 mg/kg, induced a delayed increase in glutamate levels in the nucleus accumbens (NAc). We hypothesize that repeated increases in glutamate levels produces behavioral sensitization to a selective uncompetitive N-methyl-D-aspartate (N... | ['Animals', 'Behavior, Animal', 'Central Nervous System Stimulants', 'Dizocilpine Maleate', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Excitatory Amino Acid Antagonists', 'Glutamic Acid', 'Male', 'Methamphetamine', 'Motor Activity', 'Protein Kinase C', 'Rats', 'Rats, Sprague-Dawley', 'Staurosporine'] | 15,682,296 | [['B01.050'], ['F01.145.113'], ['D27.505.696.282', 'D27.505.954.427.220'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], [... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intraperitoneal administration of cisplatin and 5-fluorouracil in residual ovarian cancer: a Phase II Gynecologic Oncology Group trial. | Forty-eight patients with persistent or recurrent epithelial ovarian cancer who had persistent or recurrent disease following intravenous (i.v.) cisplatin-based chemotherapy were treated with intraperitoneal (ip) cisplatin and 5-fluorouracil (5-FU) as salvage therapy. All patients had surgically documented minimal resi... | ['Adenocarcinoma', 'Adenocarcinoma, Clear Cell', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Cisplatin', 'Female', 'Fluorouracil', 'Humans', 'Injections, Intraperitoneal', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm, Residual', 'Ovarian Neoplasms', 'Salvage Therapy'] | 7,896,179 | [['C04.557.470.200.025'], ['C04.557.470.200.025.045'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.490'], ['M01.060.116.630'... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of extradural blockage upon glucose and urea kinetics in surgical patients. | We have determined the metabolic effects induced by the use of extradural blockage with 0.5 per cent bupivacaine hydrochloride in a group of surgical patients. Turnover rates of glucose and urea were determined isotopically using radioisotopes and studies were performed both in the basal state and during total parenter... | ['Adult', 'Aged', 'Anesthesia, Epidural', 'Autonomic Nerve Block', 'Bupivacaine', 'Female', 'Glucose', 'Humans', 'Kinetics', 'Male', 'Middle Aged', 'Parenteral Nutrition, Total', 'Proteins', 'Radioisotopes', 'Surgical Procedures, Operative', 'Urea'] | 3,114,899 | [['M01.060.116'], ['M01.060.116.100'], ['E03.155.086.131'], ['E03.155.086.711.299', 'E04.525.210.550.500'], ['D02.065.199.239', 'D02.092.146.113.239'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['M01.060.116.630'], ['E02.421.505.575', 'E02.642.500.505.750'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Cell Therapy Catapult: growing a U.K. cell therapy industry generating health and wealth. | In a recent report on the regenerative medicine sector, the U.K. House of Lords made several recommendations to enable the United Kingdom to become a global leader in this important industry. Its recommendations in this regard were many and various, covering the regulatory system, clinical trials, manufacturing, fundin... | ['Cell- and Tissue-Based Therapy', 'Clinical Trials as Topic', 'Humans', 'Regenerative Medicine', 'United Kingdom'] | 24,304,073 | [['E02.095.147'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.750'], ['Z01.542.363']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Targeted, haplotype-resolved resequencing of long segments of the human genome. | Currently, challenges exist to acquire long-range (hundreds of kilobase pairs) phase-discriminated sequence across substantial numbers of individuals. We have developed a straightforward method for isolating and characterizing specific genomic regions in a haplospecific manner. Real-time PCR is carried out to STS conte... | ['Base Sequence', 'Cloning, Molecular', 'Genome, Human', 'Genotype', 'Haplotypes', 'Humans', 'Microsatellite Repeats', 'Molecular Sequence Data', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA'] | 16,249,066 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['G05.360.340.350'], ['G05.380'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['L01.453.245.667'], ['G05.365.795.598'], ['E05.393.760.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The diagnostics of tapetoretinal dystrophies using electrophysiological methods]. | PURPOSE: The purpose of our study was to determine the diagnostic criteria of hereditary tapetoretinal dystrophies. In time of ten years we have followed the course of the disease, the manifestation and the change of the electrophysiological parameters in investigated patients.MATERIAL AND METHODS: At Dept. of Paediatr... | ['Child', 'Electrooculography', 'Electroretinography', 'Evoked Potentials, Visual', 'Female', 'Humans', 'Male', 'Retinal Dystrophies'] | 21,394,968 | [['M01.060.406'], ['E01.370.380.230.285', 'E01.370.405.245.787.285'], ['E01.370.380.225', 'E01.370.405.270'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.658']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neurogenin 3 cellular and subcellular localization in the developing and adult hippocampus. | Neurogenin 3 (Ngn3), a proneural gene controlled by the Notch receptor, is implicated in the control of dendrite morphology and synaptic plasticity of cultured hippocampal neurons. Here we report the localization and subcellular distribution of Ngn3 in the hippocampus in vivo and in neuronal cultures. In situ hybridiza... | ['Active Transport, Cell Nucleus', 'Animals', 'Antibiotics, Antineoplastic', 'Basic Helix-Loop-Helix Transcription Factors', 'Cells, Cultured', 'Fatty Acids, Unsaturated', 'Hippocampus', 'Homeodomain Proteins', 'In Situ Hybridization', 'Karyopherins', 'Mice', 'Nerve Tissue Proteins', 'Neurons', 'RNA, Messenger', 'Recep... | 20,235,092 | [['G03.143.310.100', 'G03.143.700.100'], ['B01.050'], ['D27.505.954.248.106'], ['D12.776.260.103', 'D12.776.930.125'], ['A11.251'], ['D10.251.355'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D12.776.260.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
B-lymphocytosis factor in human plasma. | Patients with acute thermal burns experience an increase of serum immunoglobulins associated with marked B-lymphocytosis during the recovery phase from the burn injury. This study was performed to delineate humoral factors which may induce the B-lymphocytosis in such patients. Plasma samples were obtained serially from... | ['Adolescent', 'Adult', 'Animals', 'B-Lymphocytes', 'Burns', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Lymphocyte Activation', 'Lymphocytosis', 'Male', 'Mice', 'Mice, Inbred C3H', 'Middle Aged'] | 1,082,759 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C26.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.5... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preliminary investigation of the STBBI Stigma Scale: Description and pilot results. | OBJECTIVES: Sexually transmitted and blood-borne infections (STBBIs) are associated with stigmatizing attitudes and beliefs, which can affect the quality of and access to health care, as well as mental health and quality of life. The current study describes the adaptation from an HIV-related stigma scale and pilot test... | ['Adult', 'Aged', 'Attitude of Health Personnel', 'Bacterial Infections', 'Blood-Borne Pathogens', 'Canada', 'Female', 'Health Personnel', 'Humans', 'Male', 'Middle Aged', 'Pilot Projects', 'Psychometrics', 'Reproducibility of Results', 'Sexually Transmitted Diseases', 'Social Stigma', 'Social Work', 'Surveys and Quest... | 29,120,307 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['C01.150.252'], ['B05.155'], ['Z01.107.567.176'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['F04.711.780'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Maxillary sinus pneumatization of an adult skull with an untreated bilateral cleft palate. | INTRODUCTION: Patients with clefts of lip, alveolus and palate show a high incidence of maxillary sinusitis. In order to evaluate sinus size as a factor in sinusitis, this study investigates maxillary sinus morphology in an adult skull with an untreated bilateral cleft.MATERIAL AND METHODS: The maxillary sinus volume (... | ['Adult', 'Cephalometry', 'Cleft Palate', 'Female', 'History, Ancient', 'Humans', 'Least-Squares Analysis', 'Male', 'Maxillary Sinus', 'Regression Analysis', 'Sinusitis', 'Skull', 'Tomography, X-Ray Computed'] | 17,071,400 | [['M01.060.116'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.500.460.185', 'C07.650.525.185', 'C16.131.621.207.540.460.185', 'C16.131.850.500.460.185', 'C16.131.850.525.185'], ['K01.400.470'], ['B01.050... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Humanities [K]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of husbands' smoking on the incidence of lung cancer in Korean women. | BACKGROUND: Although smoking remains uncommon among Korean women, lung cancer mortality is rapidly escalating.METHODS: We investigated the effects of spousal smoking in 160130 Korean women, aged 40-88, who received health insurance from the Korea Medical Insurance Corporation (KMIC). Exposure data were collected during... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Confidence Intervals', 'Female', 'Health Surveys', 'Humans', 'Incidence', 'Korea', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Poisson Distribution', 'Risk Factors', 'Sex Distribution', 'Socioeconomic Factors', 'Spouses', '... | 10,597,977 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation. | Polycomb repressive complex 2 (PRC2) is composed of EED, SUZ12, and EZH1/2 and mediates mono-, di-, and trimethylation of histone H3 at lysine 27. At least two independent subcomplexes exist, defined by their specific accessory proteins: PRC2.1 (PCL1-3, EPOP, and PALI1/2) and PRC2.2 (AEBP2 and JARID2). We show that PRC... | ['Animals', 'Binding Sites', 'Cell Line, Tumor', 'Chromatin', 'Histones', 'Humans', 'Methylation', 'Mice', 'Mouse Embryonic Stem Cells', 'Polycomb Repressive Complex 1', 'Polycomb Repressive Complex 2', 'Protein Binding', 'Protein Processing, Post-Translational', 'Ubiquitin-Protein Ligases'] | 31,521,505 | [['B01.050'], ['G02.111.570.120'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.53... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antibiotic susceptibility of clinical isolates of Prevotella bivia in Lagos, Nigeria. | The susceptibility of 40 clinical isolates of Prevotella bivia to 11 anti-anaerobic agents was determined by disk diffusion and agar dilution methods in accordance with the NCCLS (1990) recommended guidelines. With the disk diffusion method all the P. bivia tested were susceptible to rifampicin, cefoxitin, chlorampheni... | ['Anti-Bacterial Agents', 'Female', 'Humans', 'Microbial Sensitivity Tests', 'Nigeria', 'Prevotella'] | 8,835,108 | [['D27.505.954.122.085'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['Z01.058.290.190.565'], ['B03.440.080.094.640', 'B03.440.425.410.194.640']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Periapical disease and bisphosphonates induce osteonecrosis of the jaws in mice. | Osteonecrosis of the jaw (ONJ) is a well-recognized complication of antiresorptive medications, such as bisphosphonates (BPs). Although ONJ is most common after tooth extractions in patients receiving high-dose BPs, many patients do not experience oral trauma. Animal models using tooth extractions and high BP doses rec... | ['Animals', 'Bisphosphonate-Associated Osteonecrosis of the Jaw', 'Bone Density Conservation Agents', 'Diphosphonates', 'Disease Models, Animal', 'Imidazoles', 'Male', 'Mandible', 'Mice', 'Molar', 'Periapical Diseases', 'Periosteum', 'Rats', 'Zoledronic Acid'] | 23,426,919 | [['B01.050'], ['C05.116.852.087', 'C05.500.086', 'C07.320.086', 'C23.550.717.732.183'], ['D27.505.696.242'], ['D02.705.429.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D03.383.129.308'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['B01.050.150.900.649.313.992.635.505.500'], ['A14.549.167.860.525'], ['C0... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outpatient transesophageal echocardiography with intravenous propofol anesthesia in children and adolescents. | Outpatient transesophageal echocardiography (TEE) was performed in 10 children and adolescents (aged 3 to 19.5 years, mean 13.5 years; weight 12 to 91 kg, mean 49 kg), including two with Down's syndrome and one with autism, for diagnostic evaluation of issues unresolved by transthoracic echo examination (TTE). Issues f... | ['Adolescent', 'Adult', 'Ambulatory Care', 'Anesthesia, Intravenous', 'Child', 'Child, Preschool', 'Echocardiography', 'Female', 'Humans', 'Male', 'Propofol'] | 8,481,250 | [['M01.060.057'], ['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['E03.155.308'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.657.773']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Meta-analytic insights into factors influencing the repeatability of hormone levels in agricultural, ecological, and medical fields. | Interest in individual variation in hormone concentrations is rapidly increasing, particularly with regard to the evolutionary and practical implications. A key aspect of studying individual variation in any labile trait is estimating the degree of within- versus among-individual variation, but at present, we do not ha... | ['Agriculture', 'Animals', 'Behavior, Animal', 'Ecosystem', 'Female', 'Hormones', 'Humans', 'Male', 'Phenotype', 'Reproducibility of Results'] | 30,427,725 | [['J01.040'], ['B01.050'], ['F01.145.113'], ['G16.500.275.157', 'N06.230.124'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.695'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Study of the secondary structure of the C-terminal domain of the antiapoptotic protein bcl-2 and its interaction with model membranes. | Bcl-2 is a protein which inhibits programmed cell death. It is associated to many cell membranes such as mitochondrial outer membrane, endoplasmic reticulum, and nuclear envelope, apparently through a C-terminal hydrophobic domain. We have used infrared spectroscopy to study the secondary structure of a synthetic pepti... | ['Calorimetry, Differential Scanning', 'Diphenylhexatriene', 'Fluoresceins', 'Fluorescence Polarization', 'Intracellular Membranes', 'Membranes, Artificial', 'Peptides', 'Phospholipids', 'Protein Structure, Secondary', 'Proto-Oncogene Proteins c-bcl-2', 'Spectrophotometry, Infrared'] | 10,869,179 | [['E05.196.131.310', 'E05.196.370.310'], ['D02.455.326.271.665.250'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['E05.196.712.516.600.390'], ['A11.284.149.450', 'A11.284.835.514'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D12.644'], ['D10.570.755'], ['G02.111.570.820.709.600'], ['D12.64... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
COVID-19 Pandemia and Public and Global Mental Health from the Perspective of Global Health Securit. | The Coronavirus disease 2019 (COVID-19) pandemic emerged in Wuhan, China and has spread all over the world and has caused huge threats to health and lives. It has affected different frontiers of lives and induced many psychiatric individual and collective problems such as panic, anxiety, depression, post-traumatic stre... | ['Betacoronavirus', 'COVID-19', 'China', 'Coronavirus Infections', 'Global Health', 'Health Personnel', 'Humans', 'Mental Disorders', 'Mental Health', 'Pandemics', 'Pneumonia, Viral', 'Public Health', 'SARS-CoV-2'] | 32,303,023 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['Z01.252.474.164'], ['C01.925.782.600.550.200'], ['H02.403.371', 'N01.400.337'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
A confocal microscopy study of the very early cellular response to oxidative stress induced by zinc phthalocyanine sensitization. | Oxidative stress has been involved in several biological and pathological processes. Reactive oxygen species have been shown to play both beneficial and deleterious roles. The present work contributes to the understanding of the very early events of cellular response to oxidative stress. Oxidative stress was produced i... | ['Calcium', 'Cells, Cultured', 'Fibroblasts', 'Humans', 'Hydrogen-Ion Concentration', 'Indoles', 'Membrane Potentials', 'Microscopy, Confocal', 'Mitochondria', 'Mitochondrial Membranes', 'Organometallic Compounds', 'Oxidative Stress', 'Photosensitizing Agents', 'Reactive Oxygen Species'] | 16,214,028 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D03.633.100.473'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E01.370.350.515.395', 'E05.595.395'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], [... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Chronic erosion of the stomach (clinico-morphologic study)]. | Altogether 256 biopsies of the stomach from 175 patients with chronic gastric erosions diagnosed clinico-endoscopically were studied. Erosions were found histologically in 112 biopsies, in 48 cases they were estimated as acute and in 64 cases as chronic ones. Typical fibrinoid necrosis is characteristic of chronic eros... | ['Adult', 'Biopsy', 'Female', 'Gastric Mucosa', 'Granulation Tissue', 'Humans', 'Hyperplasia', 'Male', 'Middle Aged', 'Necrosis', 'Neutrophils', 'Recurrence', 'Stomach Diseases'] | 4,096,651 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A03.556.875.875.440', 'A10.615.550.291'], ['A10.165.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['M01.060.116.630'], ['C23.550.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Le Fort I maxillary osteotomy approach to surgery of the skull base. | A new modification of the transoral route involving a Le Fort I maxillotomy has been developed to offer much-improved exposure of the midline skull base. The procedure involves a standard Le Fort I osteotomy combined with division of the nasal septum and lateral pterygoid laminae, and excision of the inferior turbinate... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Dura Mater', 'Fibrin Tissue Adhesive', 'Humans', 'Maxilla', 'Middle Aged', 'Nasal Septum', 'Osteotomy', 'Skull'] | 2,585,593 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['A08.186.566.395'], ['D12.776.124.270.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['M01.060.116.630'], ['A04.531.591'], ['E04.555.580'], ['A02.835.232.781']] | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relationship between presence of cows with milk positive for Mycobacterium avium subsp. paratuberculosis-specific antibody by enzyme-linked immunosorbent assay and viable M. avium subsp. paratuberculosis in dust in cattle barns. | Paratuberculosis, or Johne's disease, in cattle is caused by Mycobacterium avium subsp. paratuberculosis, which has recently been suspected to be transmitted through dust. This longitudinal study on eight commercial M. avium subsp. paratuberculosis-positive dairy farms studied the relationship between the number of cow... | ['Animals', 'Antibodies, Bacterial', 'Bacteriological Techniques', 'Cattle', 'Dust', 'Environmental Microbiology', 'Enzyme-Linked Immunosorbent Assay', 'Milk', 'Mycobacterium avium subsp. paratuberculosis', 'Polymerase Chain Reaction'] | 23,793,639 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['E01.370.225.875.150', 'E05.200.875.150'], ['B01.050.150.900.649.313.500.380.271'], ['D20.633.222'], ['H01.158.273.540.274', 'N06.850.425'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Knowledge, Attitudes, and Beliefs Regarding Drug Abuse and Misuse among Community Pharmacists in Saudi Arabia. | Background and Objective: Several over-the-counter drugs have been documented as an essential issue in the community pharmacy setting owing to their liability to abuse. Pharmacists act as a critical monitor for these concerns and evaluate the seriousness of the patients' condition. Therefore, this study aimed to assess... | ['Adult', 'Attitude of Health Personnel', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Pharmacists', 'Saudi Arabia', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Yemen', 'Young Adult'] | 32,092,993 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.485.780', 'N02.360.780'], ['Z01.252.245.500.750'], ['C25.775', 'F03.900... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Endoscopy as a diagnostic tool in inflammatory bowel disease. | Endoscopy has become an important technique for the evaluation of patients with inflammatory bowel disease. It is used for the diagnosis as well as for the follow up of the disease. The present article reviews different aspects of intestinal endoscopy with their specific indications in inflammatory bowel diseases (IBD)... | ['Cholangiopancreatography, Endoscopic Retrograde', 'Colonoscopy', 'Endoscopy', 'Humans', 'Ileum', 'Inflammatory Bowel Diseases'] | 2,756,804 | [['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning, developmental regulation and neural localization of rat epsilon-sarcoglycan. | Mutations in the gene for epsilon sarcoglycan (epsilon-SG) are associated with a disorder of the central nervous system, the myoclonus-dystonia syndrome (MDS; DYT11). In contrast, mutations of other sarcoglycan family members lead to limb-girdle muscular dystrophies. To establish the framework for functional studies of... | ['Animals', 'Brain', 'Cell Differentiation', 'Cell Membrane', 'Cytoskeletal Proteins', 'DNA, Complementary', 'Dystonia', 'Female', 'Fetus', 'Gene Expression', 'Membrane Glycoproteins', 'Molecular Sequence Data', 'Myoclonus', 'Neurons', 'Pregnancy', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Sarcoglycans', 'Sequ... | 14,625,080 | [['B01.050'], ['A08.186.211'], ['G04.152'], ['A11.284.149'], ['D12.776.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['C10.597.350.300', 'C23.888.592.350.300'], ['A16.378'], ['G05.297'], ['D12.776.395.550', 'D12.776.543.550'], ['L01.453.245.667'], ['C10.597.350.500', 'C23.888.592... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Scaphoid fracture as a "puncher's fracture". | We investigated 18 scaphoid fractures induced by punching. The wrist position while punching was neutral to slight palmar flexion. We postulated that the mechanism of the fracture was caused by the concentration of the external force to the second metacarpus. The forces are then dispersed to the trapezium and trapezoid... | ['Adolescent', 'Adult', 'Biomechanical Phenomena', 'Carpal Bones', 'Child', 'Female', 'Fractures, Bone', 'Humans', 'Male', 'Posture', 'Radiography'] | 8,207,565 | [['M01.060.057'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['A02.835.232.087.319.150'], ['M01.060.406'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.695'], ['E01.370.350.700']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Choroid plexus cysts: a normal finding on ultrasound. | Within a period of 2.5 years, cystic structures in the choroid plexus were encountered at cerebral sonography in 70 neonates and babies (45 male, 25 female; 18 premature babies). Their prevalence in patients examined during the first 4 weeks of life (n = 55) was 3%. The size of the cysts ranged from 1-4 and, rarely, up... | ['Brain Diseases', 'Choroid Plexus', 'Cysts', 'Female', 'Follow-Up Studies', 'Humans', 'Infant, Newborn', 'Male', 'Prevalence', 'Prospective Studies', 'Reference Values', 'Ultrasonography'] | 1,437,362 | [['C10.228.140'], ['A08.186.211.140.298'], ['C04.182', 'C23.300.306'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.8... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fluorescence imaging of nitric oxide in living cells using o-phenylenediamine-rhodamine based polymeric nanosensors. | Direct real-time measurement of nitric oxide (NO) in living cells has proven quite challenging, owing in part to the lack of tools that are selective and sensitive to measure intracellular concentrations of NO. Herein we report the synthesis and characterization of polyvinyl alcohol (PVA) based nanosensors for fluoresc... | ['Animals', 'Glutathione', 'Hep G2 Cells', 'Humans', 'Hydrogen Peroxide', 'Microscopy, Fluorescence', 'Nanostructures', 'Nitric Oxide', 'Phenylenediamines', 'Rabbits', 'Rhodamines'] | 31,923,983 | [['B01.050'], ['D12.644.456.448'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['E01.370.350.515.458', 'E05.595.458'], ['J01.637.512'], ['D01.339.387', 'D01.625.550.500', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Anti-monocyte chemoattractant protein-1 gene therapy protects against focal brain ischemia in hypertensive rats. | Monocyte chemoattractant protein-1 (MCP-1) is expressed in the ischemic cortex after focal brain ischemia and appears to exacerbate ischemic damage. The authors examined the effect of gene transfer of dominant negative MCP-1, called 7ND, 90 minutes after induction of focal brain ischemia in hypertensive rats. Adenovira... | ['Adenoviridae', 'Animals', 'Brain Ischemia', 'Cerebrovascular Circulation', 'Chemokine CCL2', 'Gene Expression', 'Genetic Therapy', 'Hypertension', 'Immunohistochemistry', 'Leukocytes', 'Macrophages', 'Male', 'Rats', 'Transgenes', 'beta-Galactosidase'] | 15,625,410 | [['B04.280.030'], ['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G09.330.100.159'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['G05.297'], ['E02.095.301', 'E05.393.420.301'], ['C14.907.489'], [... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Multitrait genome-wide association analysis of Populus trichocarpa identifies key polymorphisms controlling morphological and physiological traits. | Genome-wide association studies (GWAS) have great promise for identifying the loci that contribute to adaptive variation, but the complex genetic architecture of many quantitative traits presents a substantial challenge. We measured 14 morphological and physiological traits and identified single nucleotide polymorphism... | ['Down-Regulation', 'Gene Regulatory Networks', 'Genes, Plant', 'Genome-Wide Association Study', 'Genotype', 'Geography', 'Inheritance Patterns', 'Multivariate Analysis', 'Plant Stomata', 'Polymorphism, Single Nucleotide', 'Populus', 'Principal Component Analysis', 'Quantitative Trait, Heritable'] | 30,843,213 | [['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.360.080.689.360'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['G05.380'], ['H01.277.500'], ['G05.420'], [... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Estimation of the levels of anxiety, emotional endurance and placement of control of female patients hospitalized with coronary disease]. | Spielberger's State--Trait Anxiety Inventory, Z. Bizo?'s Questionnaire of Neurotic Symptoms as the indicator of emotional endurance and Rotter's Internal-External Control Scale were used for the analysis of a problem concerning the mechanisms of psychological functioning of female patients hospitalized with coronary di... | ['Adult', 'Anxiety Disorders', 'Coronary Disease', 'Emotions', 'Female', 'Hospitalization', 'Humans', 'Middle Aged', 'Psychological Tests', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 8,134,496 | [['M01.060.116'], ['F03.080'], ['C14.280.647.250', 'C14.907.585.250'], ['F01.470'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Speech recognition in one- and two-talker maskers in school-age children and adults: Development of perceptual masking and glimpsing. | Children perform more poorly than adults on a wide range of masked speech perception paradigms, but this effect is particularly pronounced when the masker itself is also composed of speech. The present study evaluated two factors that might contribute to this effect: the ability to perceptually isolate the target from ... | ['Acoustic Stimulation', 'Adolescent', 'Adolescent Behavior', 'Adult', 'Age Factors', 'Auditory Threshold', 'Child', 'Child Behavior', 'Child, Preschool', 'Cues', 'Female', 'Humans', 'Male', 'Noise', 'Perceptual Masking', 'Psychoacoustics', 'Recognition, Psychology', 'Speech Perception', 'Speech Reception Threshold Tes... | 28,464,682 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['F01.145.022'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Directing the morphology and differentiation of skeletal muscle cells using oriented cellulose nanowhiskers. | Radially oriented submonolayer surfaces of 10-15 nm diameter cellulose nanowhiskers (CNWs) were prepared by spin-coating. The response of myoblasts (muscle cells) to the surfaces was assessed using atomic force microscopy (AFM), immunocytochemistry, and image analysis. Despite the small size of the CNWs, the myoblasts ... | ['Animals', 'Cell Differentiation', 'Cells, Cultured', 'Cellulose', 'Focal Adhesions', 'Image Processing, Computer-Assisted', 'Immunoenzyme Techniques', 'Mice', 'Microscopy, Atomic Force', 'Muscle, Skeletal', 'Myoblasts', 'Nanotechnology', 'Plasticizers', 'Urochordata'] | 20,690,614 | [['B01.050'], ['G04.152'], ['A11.251'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['A11.284.149.165.165.285'], ['L01.224.308'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.666.400', 'E05.595.666... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
S-adenosyl-L-methionine prevents ischemic neuronal death. | The effect of S-adenosyl-L-methionine (SAM) on neuronal degeneration induced by transient forebrain ischemia was studied in rats. Bilateral occlusion of the common carotid arteries for 30 min in a 4-vessel occlusion model caused degeneration of CA1 neurons of the hippocampus. When SAM-HCl or SAM sulphate tosylate (SAM-... | ['Animals', 'Brain Ischemia', 'Cell Survival', 'Hippocampus', 'Male', 'Nerve Degeneration', 'Neurons', 'Rats', 'Rats, Inbred Strains', 'S-Adenosylmethionine'] | 3,436,368 | [['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G04.346'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['C23.550.737'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D02.886.030.676.180', 'D0... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissecting sub-epicardial haematoma: a rare complication with the use of Octopus suction mechanical stabiliser. | Mechanical heart stabilisers are the most important method of anastomotic field immobilisation in off pump coronary artery bypass (OPCAB) surgery. The new generations of stabilisers are small, versatile and relatively free of complications. We report a patient who developed a dissecting sub-epicardial haematoma followi... | ['Aged', 'Coronary Artery Bypass, Off-Pump', 'Heart Diseases', 'Hematoma', 'Humans', 'Male', 'Pericardium', 'Suction'] | 17,317,313 | [['M01.060.116.100'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.520.220.189'], ['C14.280'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.795', 'A10.615.789.470'], ['E04.237.890']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Functionalized Agarose Self-Healing Ionogels Suitable for Supercapacitors. | Agarose has been functionalized (acetylated/carbanilated) in an ionic liquid (IL) medium of 1-butyl-3-methylimidazolium acetate at ambient conditions. The acetylated agarose showed a highly hydrophobic nature, whereas the carbanilated agarose could be dissolved in water as well as in the IL medium. Thermoreversible ion... | ['Acetylation', 'Electric Capacitance', 'Electrochemistry', 'Gels', 'Imidazoles', 'Ionic Liquids', 'Mechanical Phenomena', 'Methanol', 'Sepharose'] | 26,280,813 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['G01.358.500.249.270'], ['H01.181.529.307'], ['D20.280.320', 'D26.255.165.320'], ['D03.383.129.308'], ['D27.720.844.500'], ['G01.374'], ['D02.033.623'], ['D09.698.813']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Palladium and gold nanoparticle array films formed by using self-assembly of block copolymer. | The well-arrayed Pd and Au nanoparticle thin films were successfully prepared by making use of self-assembled PS-b-P4VP block copolymer (BCP) as a mask for the reduction of PdCl2 deposited on glass substrate. The films consisted of spherialcal nanoparticles with an average diameter of about 45 nm. For monitoring the si... | ['Gold', 'Microscopy, Atomic Force', 'Nanostructures', 'Nanotechnology', 'Palladium', 'Polystyrenes', 'Polyvinyls', 'Pyridines', 'Spectrophotometry'] | 17,025,099 | [['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['D01.268.556.680', 'D01.268.956.718', 'D01.552.544.680'], ['D02.455.426.559.389.150.750.800.830', 'D05.750.716.579', 'D25.720.716.579', 'J01.637.051.720.716.579']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Feline generalized epilepsy induced by tranexamic acid (AMCA). | Epileptic activities induced by topical application of tranexamic acid (AMCA) and penicillin to the cortex of 12 cats in acute experiments were compared. Both substances when diffusely applied on a wide cortical area of both hemispheres at very low concentration produced an EEG pattern consisting of spike-wave bursts s... | ['Administration, Topical', 'Animals', 'Cats', 'Cerebral Cortex', 'Cyclohexanecarboxylic Acids', 'Dose-Response Relationship, Drug', 'Electric Stimulation', 'Electroencephalography', 'Female', 'Injections, Intramuscular', 'Injections, Intravenous', 'Male', 'Models, Biological', 'Penicillins', 'Seizures', 'Thalamic Nucl... | 7,056,249 | [['E02.319.267.120'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.500'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.723.402'], ['E01.370.376.300', 'E01.370.405.245'], ['E02.319.267.530.460'], ['E02.319.267.082.750', 'E02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Is halogen bonding the basis for iodothyronine deiodinase activity? | Density functional theory studies of S...X and Se...X (X = Br, I) halogen-bonding interactions are used to interpret the selection of selenium and iodine for thyroid hormone signaling. A new mechanism for dehalogenation in terms of halogen bonding is proposed. The activation barriers for deiodination of an aromatic iod... | ['Catalytic Domain', 'Hydrocarbons, Iodinated', 'Iodide Peroxidase', 'Models, Molecular', 'Molecular Dynamics Simulation', 'Molecular Structure', 'Selenium'] | 20,504,030 | [['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D02.455.526.581'], ['D08.811.682.732.525'], ['E05.599.595'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570', 'G02.466'], ['D01.268.185.850', 'D01.578.700']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Early detection and prevention of mental illness: the Mauritius project. A preliminary report. | The experimental manipulation method is in general not feasible in studies of the etiology of severe mental illness, whereas this method can be used in studies pertaining to primary prevention, because possible preventive methods would most likely be of a protective or beneficial nature. Preventive experimentation requ... | ['Age Factors', 'Autonomic Nervous System', 'Child, Preschool', 'Family', 'Female', 'Humans', 'Interview, Psychological', 'Male', 'Mass Screening', 'Mauritius', 'Mental Disorders', 'Orientation', 'Schizophrenia', 'Socioeconomic Factors', 'Surveys and Questionnaires'] | 1,232,558 | [['N05.715.350.075', 'N06.850.490.250'], ['A08.800.050'], ['M01.060.406.448'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.78... | ['Health Care [N]', 'Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Changes in Optic Nerve Head Vessel Density After Acute Primary Angle Closure Episode. | Purpose: To evaluate the changes in circumpapillary vessel density (cpVD) and retinal nerve fiber layer (RNFL) thickness after an acute primary angle closure (APAC) episode.Methods: Twenty-eight patients (28 pair of eyes) with unilateral APAC and 39 normal subjects (64 eyes) were included in this prospective, observati... | ['Acute Disease', 'Aged', 'Blood Flow Velocity', 'Female', 'Glaucoma, Angle-Closure', 'Gonioscopy', 'Humans', 'Imaging, Three-Dimensional', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Nerve Fibers', 'Optic Disk', 'Prospective Studies', 'ROC Curve', 'Retinal Ganglion Cells', 'Retinal Vessels', 'Tomography, Optical C... | 30,721,302 | [['C23.550.291.125'], ['M01.060.116.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['C11.525.381.056'], ['E01.370.380.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['G14.440'], ['M01.060.116.630'], ['A08.675.542', 'A11.671.501'], ['A08.800.800.120.680.660', 'A09.371... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Aspartate aminotransferase to platelet ratio can reduce the need for transient elastography in Chinese patients with chronic hepatitis B. | In the absence of liver biopsy and transient elastography (TE), aspartate aminotransferase to platelet ratio (APRI), fibrosis-4 score (FIB-4), and gammaglutamyl transpeptidase to platelet ratio (GPR) are simple and inexpensive methods for the detection of liver fibrosis.AIMS: We compared the performance of APRI, FIB-4,... | ['Adult', 'Aspartate Aminotransferases', 'Biomarkers', 'China', 'Elasticity Imaging Techniques', 'Female', 'Hepatitis B, Chronic', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Platelet Count', 'Poverty', 'ROC Curve', 'Retrospective Studies', 'Sensitivity and Specificity', 'Severity of Illness Index', 'gamma-Glu... | 31,804,310 | [['M01.060.116'], ['D08.811.913.477.700.225'], ['D23.101'], ['Z01.252.474.164'], ['E01.370.350.850.270'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['M0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Comparison of left and right ventricular blood flow responses during arterial pressure reduction in the autonomically blocked dog: evidence for right ventricular autoregulation. | The effect of reducing systemic arterial pressure with an arteriovenous fistula on left and right ventricular myocardial blood flow was studied in 17 anaesthetised, open chest, autonomically blocked dogs. Global and regional myocardial blood flows were measured with radioactive microspheres. As mean arterial pressure w... | ['Animals', 'Blood Flow Velocity', 'Blood Pressure', 'Coronary Circulation', 'Coronary Vessels', 'Dogs', 'Heart Ventricles', 'Hemodynamics', 'Vascular Resistance', 'Ventricular Outflow Obstruction'] | 3,167,924 | [['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.100.324'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541.560'], ['G09.330.380'], ['G09.330.380.921'], ['C14.280.955']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma cytokines, glomerular filtration rate and adipose tissue cytokines gene expression in chronic kidney disease (CKD) patients. | BACKGROUND AND AIM: Systemic inflammation is a hallmark of chronic kidney disease (CKD) and obesity represents a major risk factor for CKD. We investigated the relationship between plasma interleukin-6 (IL-6) and tumour necrosis factor-á (TNF-á) and the glomerular filtration rate (GFR) in 75 stage 2-5 CKD patients.METH... | ['Adipose Tissue', 'Adult', 'Aged', 'Case-Control Studies', 'Female', 'Gene Expression', 'Glomerular Filtration Rate', 'Humans', 'Interleukin-1beta', 'Interleukin-6', 'Interleukin-8', 'Linear Models', 'Male', 'Middle Aged', 'RNA, Messenger', 'Renal Insufficiency, Chronic', 'Tumor Necrosis Factor-alpha'] | 21,906,921 | [['A10.165.114'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.297'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Prevention of the syndrome of barometeorosensitivity in the Arctic Circle]. | Causes and mechanisms of barometeorosensitivity progression in servicemen, serving in the Arctic Circle, are described in this article. The authors proved conclusively the necessity of active detection of barometeorosensitive servicemen and case follow-up. The authors came to conclusion that it is necessary to include ... | ['Arctic Regions', 'Atmospheric Pressure', 'Cold Climate', 'Follow-Up Studies', 'Humans', 'Male', 'Military Personnel', 'Syndrome', 'Young Adult'] | 24,000,607 | [['Z01.208'], ['G16.500.750.274', 'N06.230.300.100.185'], ['G16.500.275.071.275', 'N06.230.300.100.250.275'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['C23.550.288.500'], ['M01.060.116.815']] | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine. | Sulfonamide antimicrobials such as sulfamethoxazole (SMX) have been associated with drug hypersensitivity reactions, particularly in patients with AIDS. A reactive oxidative metabolite, sulfamethoxazole-nitroso (SMX-NO), forms drug-tissue adducts that elicit a T-cell response. Antioxidants such as ascorbic acid (AA) an... | ['Animals', 'Anti-Infective Agents', 'Antioxidants', 'Ascorbic Acid', 'Ascorbic Acid Deficiency', 'Cell Proliferation', 'Cytochrome-B(5) Reductase', 'Cytochromes b5', 'Drug Hypersensitivity', 'Glutathione', 'Guinea Pigs', 'Inactivation, Metabolic', 'Liver', 'Male', 'Sulfamethoxazole', 'T-Lymphocytes'] | 20,221,587 | [['B01.050'], ['D27.505.954.122'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['C18.654.521.500.133.115'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.682.608.191.237', 'D12.776.331.186'], ['D08.244.187.500', 'D12.776.422.220.187.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Health promotion by International Olympic Sport Federations: priorities and barriers. | OBJECTIVE: To identify changes in International Federations' priorities and the barriers to implementing athlete and global health initiatives. Results should influence the work of the International Federation medical committees, the IOC and the Association of Summer Olympic International Federation.METHODS: The 28 Sum... | ['Global Health', 'Health Plan Implementation', 'Health Promotion', 'Health Services Needs and Demand', 'Humans', 'International Agencies', 'Sports', 'Surveys and Questionnaires'] | 30,877,137 | [['H02.403.371', 'N01.400.337'], ['N03.349.300'], ['I02.233.332.445', 'N02.421.726.407.579'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.514'], ['I03.450.642.845'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Toxicity of cleaning agents for removal of grease from wounds. | Industrial injuries are often open wounds contaminated with grease. Commercial compounds used for removing grease from intact skin are composed of petroleum distillates. These products are occasionally used to remove grease from open wounds. Using an animal model, this study examines the use of commercial compounds in ... | ['Animals', 'Detergents', 'Inflammation', 'Male', 'Rats', 'Rats, Inbred Strains', 'Skin', 'Surface-Active Agents', 'Wound Healing'] | 2,301,881 | [['B01.050'], ['D27.720.877.265', 'J01.516.381'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A17.815'], ['D27.720.877'], ['G16.762.891']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The effect of contraceptive steroids on hypothalamic-pituitary function. | A study was performed to obtain additional information about the effects of oral contraceptives on pituitary function. A sequential pituitary stimulation test (SST) was used to study normal control women who then received either a combination pill with 50 mug of ethinyl estradiol or an injectable or oral progestin for ... | ['Contraceptives, Oral', 'Contraceptives, Oral, Synthetic', 'Female', 'Follicle Stimulating Hormone', 'Growth Hormone', 'Humans', 'Hypoglycemia', 'Hypothalamo-Hypophyseal System', 'Insulin', 'Luteinizing Hormone', 'Medroxyprogesterone', 'Pituitary Hormone-Releasing Hormones', 'Pregnancy', 'Prolactin', 'Thyrotropin', 'T... | 403,765 | [['D27.505.696.875.360.276.210', 'D27.505.954.705.360.276.210'], ['D27.505.696.875.360.276.210.443', 'D27.505.954.705.360.276.210.443'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.11... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Renal Encephalitozoon (Septata) intestinalis infection in a patient with AIDS. Post-mortem identification by means of transmission electron microscopy and PCR. | We describe the occurrence of renal Encephalitozoon (Septata) intestinalis infection in a 35-year-old AIDS patient who died with disseminated tuberculosis. The patient did not complain of specific symptoms involving the kidney or lower urinary tract during life, but at autopsy, light microscopic examination of the kidn... | ['AIDS-Related Opportunistic Infections', 'Acquired Immunodeficiency Syndrome', 'Adult', 'Animals', 'Autopsy', 'Blotting, Southern', 'DNA, Protozoan', 'Encephalitozoon', 'Encephalitozoonosis', 'Fatal Outcome', 'Humans', 'Kidney Diseases', 'Male', 'Microscopy, Electron', 'Polymerase Chain Reaction'] | 9,672,195 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['B01.0... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Histotopography of changes in the enzyme activity of rat brain exposed to fluorophenazine]. | The influence of fluorophenazine on succinic-, citric acid-, NAD-H2-and NADP-H2-dehydrogenases in different structures of rat brain was investigated by histochemical methods. Three hours after a single subcutaneous injection of fluorophenazine (1 and 5 mg/kg) the enzymatic activity was the greatest in the limbic and th... | ['Animals', 'Brain', 'Fluphenazine', 'Isocitrate Dehydrogenase', 'Male', 'NADH, NADPH Oxidoreductases', 'Rats', 'Succinate Dehydrogenase'] | 1,225,397 | [['B01.050'], ['A08.186.211'], ['D02.886.369.326', 'D03.633.300.783.326'], ['D08.811.682.047.820.475'], ['D08.811.682.608'], ['B01.050.150.900.649.313.992.635.505.700'], ['D05.500.562.750.249.500', 'D08.811.600.250.500.750.500', 'D08.811.600.250.875.249.500', 'D08.811.682.660.385.500', 'D08.811.682.830.249.500', 'D12.7... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pseudo aneurysm of a 21 year old ePTFE femoro-femoral crossover graft: successful endovascular repair using an ePTFE lined nitinol stent graft. | With the advancement of technology and manufacturing of prosthetic grafts, non- anastomotic pseudoaneurysm arising from a graft is now uncommon. Here we report a case of non-anastomotic pseudo aneurysm occurring 21 years after implantation of ePTFE femoro-femoral crossover graft. An 80 year old female with a previous h... | ['Aged, 80 and over', 'Alloys', 'Aneurysm, False', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Endovascular Procedures', 'Female', 'Femoral Artery', 'Femoral Vein', 'Humans', 'Polytetrafluoroethylene', 'Prosthesis Design', 'Reoperation', 'Stents', 'Time Factors', 'Tomography, X-Ray Computed', 'T... | 21,411,465 | [['M01.060.116.100.080'], ['D01.552.033', 'D25.058', 'J01.637.051.058'], ['C14.907.055.090'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['E04.100.814.529', 'E04.502.382'], ['A07.015.114.351'], ['A07.015.908.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.395.616', 'D25.720.395.616', 'J0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Rupatadine and its effects on symptom control, stimulation time, and temperature thresholds in patients with acquired cold urticaria. | BACKGROUND: Patients with acquired cold urticaria (ACU) show itchy wheals during cold exposure. This disturbing condition involves histamine and platelet-activating factor in its pathogenesis. Rupatadine is a dual antagonist of both histamine and platelet-activating factor.OBJECTIVE: To assess rupatadine efficacy in pr... | ['Adult', 'Cold Temperature', 'Cyproheptadine', 'Double-Blind Method', 'Environmental Exposure', 'Female', 'Histamine Antagonists', 'Humans', 'Male', 'Middle Aged', 'Platelet Activating Factor', 'Pruritus', 'Treatment Outcome', 'Urticaria'] | 20,143,651 | [['M01.060.116'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D02.455.426.559.847.181.384.340', 'D03.383.621.160', 'D04.615.181.384.340'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Studies of the roles of ADP-ribosylation factors and phospholipase D in phorbol ester-induced membrane ruffling. | In this study, we have explored the roles of ADP-ribosylation factors (ARFs), phospholipase D (PLD) isozymes, and arfaptins in phorbol ester (PMA)-induced membrane ruffling in HeLa cells. PMA stimulation induced ruffling and translocated cortactin to the plasma membrane. The cortactin translocation was inhibited by dom... | ['ADP-Ribosylation Factor 1', 'ADP-Ribosylation Factors', 'Adaptor Proteins, Signal Transducing', 'Cell Membrane', 'Cortactin', 'Genes, Dominant', 'HeLa Cells', 'Humans', 'Microfilament Proteins', 'Phospholipase D', 'Tetradecanoylphorbol Acetate', 'Tissue Distribution', 'Transfection', 'rac1 GTP-Binding Protein'] | 15,389,577 | [['D08.811.277.040.330.300.400.100.100', 'D12.644.360.525.100.100', 'D12.776.157.325.515.100.100', 'D12.776.476.525.100.100', 'D12.776.543.990.300.150'], ['D08.811.277.040.330.300.400.100', 'D12.644.360.525.100', 'D12.776.157.325.515.100', 'D12.776.476.525.100'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Klotho protein supplementation reduces blood pressure and renal hypertrophy in db/db mice, a model of type 2 diabetes. | AIMS: Klotho interacts with various membrane proteins, such as receptors for transforming growth factor (TGF)-â and insulin-like growth factor (IGF), to alter their function. Renal expression of klotho is diminished in diabetes. The present study examined whether exogenous klotho protein supplementation ameliorates kid... | ['Animals', 'Blood Pressure', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Glomerular Filtration Rate', 'Glucuronidase', 'Hypertrophy', 'Kidney', 'Male', 'Mice', 'Renin-Angiotensin System', 'Signal Transduction'] | 30,251,773 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C18.452.394.750.149', 'C19.246.300'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['E01.370.390.400.300', 'G08.852.357'], ['D08.811.277.450.426'], ['C23.300.775'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['G03.820', 'G0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Resource management of cataract patients: can visual rehabilitation be achieved in three visits? | PURPOSE: To assess the feasibility and acceptability of reduced postoperative follow-up after phacoemulsification using a scleral tunnel technique.SETTING: Cataract service of a large free-standing eye hospital in a capital city.METHODS: In this pilot study, patients with age-related cataract requiring surgery were pro... | ['Episode of Care', 'Eyeglasses', 'Feasibility Studies', 'Health Resources', 'Humans', 'Patient Satisfaction', 'Phacoemulsification', 'Pilot Projects', 'Postoperative Care', 'Prospective Studies', 'Refractive Errors', 'Sclera', 'Suture Techniques', 'Vision Disorders'] | 8,844,384 | [['E02.760.300', 'N02.421.585.300'], ['E07.632.500.300'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['N03.349.340', 'N05.300.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evolving sea urchin histone genes--nucleotide polymorphisms in the H4 gene and spacers of Strongylocentrotus purpuratus. | We present a comparison of spacer and coding sequences of histone gene repeats from four Strongylocentrotus purpuratus individuals. Sequences of two previously cloned units (pCO2 and pSp2) were compared with three new histone gene clones, two of them from a single individual. Within a 1.7-kb region, 59 polymorphic site... | ['Alleles', 'Animals', 'Base Sequence', 'Codon', 'Histones', 'Mutation', 'Phylogeny', 'Polymorphism, Genetic', 'Repetitive Sequences, Nucleic Acid', 'Sea Urchins'] | 6,439,878 | [['G05.360.340.024.340.030'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['G05.365.590'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.365.795'],... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
k-RAS | OBJECTIVE: The aim of this study was to evaluate the relationship between k-RAS gene mutation and the resistance to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment in patients with nonsmall-cell lung cancer (NSCLC).METHODS: Forty-five pathologies confirmed NSCLC patients who received EGF... | ['Adult', 'Aged', 'Carcinoma, Non-Small-Cell Lung', 'Drug Resistance, Neoplasm', 'ErbB Receptors', 'Female', 'Gefitinib', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Protein Kinase Inhibitors', 'Proto-Oncogene Proteins p21(ras)', 'Quinazolines'] | 28,901,317 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G07.690.773.984.395'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['D03.633.100.786.469'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Anaerobic infection and its effect on the immune status of patients with acute destruction of the lungs]. | From studying immunological reactivity in dynamics in 107 patients with acute destructions of the lungs, the authors proved that the severity and duration of the disorders are determined to a great extent by the presence of anaerobic infection in a pure form (18 patients) or in association with aerobic microflora (23 p... | ['Acute Disease', 'Adult', 'Aged', 'B-Lymphocytes', 'Bacteria, Anaerobic', 'Bacterial Infections', 'Humans', 'Immunoglobulins', 'Lung Diseases', 'Lymphocytes', 'Middle Aged', 'Respiratory Tract Infections', 'Rosette Formation', 'T-Lymphocytes'] | 2,787,268 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['B03.130'], ['C01.150.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Likely Introduction Date of Schmallenberg Virus into France According to Monthly Serological Surveys in Cattle. | To estimate the date of introduction of Schmallenberg virus (SBV) into France, the prevalence of antibodies against the virus was determined monthly in cattle from two northern departments from August 2011 to April 2012. Seropositive cattle were detected from October 2011 in both departments with a prevalence of 55.6% ... | ['Animals', 'Antibodies, Viral', 'Bunyaviridae Infections', 'Cattle', 'Cattle Diseases', 'Dairying', 'Female', 'France', 'Orthobunyavirus', 'Prevalence', 'Seasons', 'Seroepidemiologic Studies', 'Surveys and Questionnaires'] | 24,330,549 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C01.925.782.147'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['J01.040.246'], ['Z01.542.286'], ['B04.820.480.750.640'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Effect of a single oral dose of DDT on lipid metabolism in rat. | A single oral dose of 1,1,1-trichloro-2-2-bis (p-chlorophenyl)ethane (DDT) (600 mg/kg body weight) was given to rats and the levels of various lipids in adipose tissue, liver and plasma were studied. No alteration was observed in the levels of various lipid classes in these tissues except for a decrease in the phosphol... | ['Adipose Tissue', 'Animals', 'DDT', 'Lipid Metabolism', 'Lipids', 'Lipoprotein Lipase', 'Liver', 'Male', 'Rats'] | 7,222,101 | [['A10.165.114'], ['B01.050'], ['D02.455.526.439.255'], ['G03.458'], ['D10'], ['D08.811.277.352.100.430'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Single proton counting at the RIKEN cell irradiation facility. | We present newly developed tapered capillaries with a scintillator window, which enable us to count single protons at the RIKEN cell irradiation setup. Their potential for performing single proton irradiation experiments at our beamline setup is demonstrated with CR39 samples, showing a single proton detection fidelity... | ['Cells', 'Probability', 'Protons', 'Scintillation Counting'] | 26,329,229 | [['A11'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['E05.799.700']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Current issues in species identification for forensic science and the validity of using the cytochrome oxidase I (COI) gene. | Species identification techniques commonly utilized in Australian Forensic Science laboratories are gel immunodifussion antigen antibody reactions and hair comparison analysis. Both of these techniques have significant limitations and should be considered indicative opinion based tests. The Barcode of Life Initiative a... | ['Animals', 'Conservation of Natural Resources', 'Crime', 'DNA Fingerprinting', 'DNA Primers', 'Databases, Genetic', 'Electron Transport Complex IV', 'Humans', 'Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Species Specificity'] | 20,563,888 | [['B01.050'], ['J01.256', 'N06.230.080'], ['I01.198.240', 'I01.880.735.191'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['D05.500.562.374', 'D08.811.600... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Thymic sensitivity to hypoxic condition in young and old rats. Age-dependent expression of NF-kappaB. | Oxygen keeps the entire enzymatic machinery in its physiological state. Senescence is associated with damage caused by oxidative stress, affecting also the immune system. In this study the effect of chronic hypoxia for 12 days on young and elderly rat thymus was investigated. The significant changes in cell thymic orga... | ['Age Factors', 'Animals', 'Blotting, Western', 'Hypoxia', 'Immunohistochemistry', 'Male', 'NF-kappa B', 'Rats', 'Rats, Wistar', 'Thymus Gland'] | 12,213,558 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C23.888.852.079'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', '... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Role for compatible solutes glycine betaine and L-carnitine in listerial barotolerance. | Increased listerial barotolerance at elevated osmolarity is attributed, in part, to the presence of accumulated betaine and L-carnitine. The percentage of listerial survival following exposure to 400 MPa for 5 min increased from 0.008 to 0.02% with added L-carnitine (5 mM) and to 0.05% with added betaine (5 mM). Furthe... | ['Betaine', 'Carnitine', 'Culture Media', 'Gene Expression Regulation, Bacterial', 'Hydrostatic Pressure', 'Listeria', 'Osmolar Concentration', 'Sodium Chloride'] | 15,574,960 | [['D02.092.877.883.077', 'D02.675.276.125'], ['D02.092.877.883.099'], ['D27.720.470.305', 'E07.206'], ['G05.308.300'], ['G01.374.715.352'], ['B03.353.500.500', 'B03.510.100.500', 'B03.510.460.400.410.485'], ['G02.640'], ['D01.210.450.150.875', 'D01.857.650']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of scoring systems in patients with haematological malignancy. | UNLABELLED: The utility of predictive systems in patients with haematological malignancy stems both from the heterogeneity of disease presentation and from the inherent disadvantages of therapy. There is an acute morbidity and mortality associated with chemotherapy and bone marrow transplantation, a need for long term ... | ['Health Status Indicators', 'Hematologic Diseases', 'Humans', 'Immunoglobulin G', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymphoma', 'Multivariate Analysis', 'Myelodysplastic Syndromes', 'Prognosis', 'Survival Analysis'] | 16,720,465 | [['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['C15.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['C04.557.337.428.080.125', 'C15.604.515.560.080.125', 'C20... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Lung Biopsy Findings in Severe Pulmonary Illness Associated With E-Cigarette Use (Vaping). | OBJECTIVES: The aim of this report is to describe the lung biopsy findings in vaping-associated pulmonary illness.METHODS: Lung biopsies from eight patients with vaping-associated pulmonary illness were reviewed.RESULTS: The biopsies were from eight men (aged 19-61 years) with respiratory symptoms following e-cigarette... | ['Adult', 'Biopsy', 'Humans', 'Lung', 'Lung Diseases', 'Male', 'Middle Aged', 'Vaping', 'Young Adult'] | 31,621,873 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C08.381'], ['M01.060.116.630'], ['F01.145.805.500'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Idenfication of microRNAs profiles in nasopharyngeal carcinoma]. | OBJECTIVE: To filtrate and prove the different microRNAs (miRs) profiles in nasopharyngeal carcinoma.METHOD: Screening the different expressions of miRs between nasopharyngeal carcinoma and the inflammatory tissues by the application of expression profiling of chip high-throughput and large-scale microarray analysis. T... | ['Carcinoma', 'Gene Expression Profiling', 'Humans', 'MicroRNAs', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Oligonucleotide Array Sequence Analysis'] | 25,248,265 | [['C04.557.470.200'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['C04.557.470.200.623', 'C04.588.443.665.710.650.500', 'C07.550.350.650.500', 'C07.550.745.650.500', 'C09.647.710.650.500', 'C09.775.350.650.500', 'C09.775.549.6... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Helicobacter pylori induces AGS cell motility and elongation via independent signaling pathways. | Helicobacter pylori induces motogenic and cytoskeletal responses in gastric epithelial cells. We demonstrate that these responses can be induced via independent signaling pathways that often occur in parallel. The cag pathogenicity island appears to be nonessential for induction of motility, whereas the elongation phen... | ['Antigens, Bacterial', 'Bacterial Proteins', 'Cell Movement', 'Cells, Cultured', 'Cytoskeleton', 'Epithelial Cells', 'Gastric Mucosa', 'Gene Expression Regulation, Bacterial', 'Helicobacter pylori', 'Humans', 'Signal Transduction', 'Transfection', 'Virulence'] | 15,155,677 | [['D23.050.161'], ['D12.776.097'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A11.284.430.214.190.750'], ['A11.436'], ['A03.556.875.875.440', 'A10.615.550.291'], ['G05.308.300'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820', 'G04.835'], ['E05.39... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization and photochemical and antibacterial properties of highly stable silver nanoparticles prepared on montmorillonite clay in n-hexanol. | Ag nanoparticles (NPs) of approximately 2.5±0.6 nm in size with high stability were prepared on montmorillonite clay in n-hexanol ([Ag NP/clay]). The aqueous suspensions of Ag NP/clay obtained were colored pale yellow to gray, and an intense yellow surface plasmon band was observed at approximately 397-422 nm at a [Ag(... | ['2-Propanol', 'Anti-Bacterial Agents', 'Bentonite', 'Escherichia coli', 'Hexanols', 'Hydroxyl Radical', 'Metal Nanoparticles', 'Photochemical Processes', 'Silver', 'Surface Plasmon Resonance', 'Time Factors'] | 20,172,529 | [['D02.033.755.615'], ['D27.505.954.122.085'], ['D01.056.050.075.100', 'D01.578.725.025.100', 'D01.650.550.050.075.100', 'D01.837.725.700.760.050.100'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.033.415.510', 'D10.289.510'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['J01.63... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Open clinical trial of roxithromycin in patients of Plateau Hospitals, Jos in upper and lower respiratory tract infections. | An open clinical study to assess the efficacy and tolerance of Roxithromycin 150 mg twice daily was carried out amongst Nigerian patients with upper and lower respiratory tract infections at Plateau Hospital Jos. Twenty-two patients aged between 13 and 86 years comprising of twelve women, seven men and three children c... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Bronchitis', 'Drug Resistance, Microbial', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nigeria', 'Otitis Media', 'Respiratory Tract Infections', 'Roxithromycin', 'Tonsillitis'] | 8,634,230 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.058.290.190.565'], ['C09.218.705.663... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Fistula elevation procedure: experience with 295 consecutive cases during a 7-year period. | BACKGROUND: Up to 50% of AV fistulas fail to mature, primarily because of problems with fistula cannulation. Fistula elevation procedure (FEP) is a simple superficialization procedure where the fistula is surgically exposed, mobilized, and elevated into a more superficial position for the purpose of facilitating AV fis... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Arm', 'Arteriovenous Shunt, Surgical', 'Catheterization', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Leg', 'Male', 'Middle Aged', 'Renal Dialysis', 'Reoperation', 'Treatment Outcome', 'Vascular Patency'] | 18,471,759 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A01.378.800.075'], ['E04.035.087', 'E04.100.814.868.249'], ['E02.148', 'E05.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['A01.378.610.500'], ['M01.060.116.630'], ['E... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Crosswire for recanalization of total occlusive coronary arteries. | Coronary angioplasty of total occlusions is technically difficult and is associated with limited success rates. The procedural outcome is mainly determined by the underlying pathological process. Recanalization of total occlusions is aimed at finding the passage with least resistance, without causing dissection or perf... | ['Adult', 'Aged', 'Angioplasty, Balloon, Coronary', 'Chronic Disease', 'Coronary Angiography', 'Coronary Disease', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Secondary Prevention', 'Stents', 'Treatment Outcome'] | 9,829,898 | [['M01.060.116'], ['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['C23.550.291.500'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A stochastic model for the evolution of autocorrelated DNA sequences. | Currently used stochastic models of DNA sequence evolution assume independent and identically distributed nucleotide sites. They are too simple to account for dependence structures obviously present in molecular data. Up to now more realistic stochastic models for nucleotide substitutions have been considered intractab... | ['Animals', 'Biological Evolution', 'DNA', 'DNA, Mitochondrial', 'Mammals', 'Markov Chains', 'Mutation', 'RNA, Bacterial', 'RNA, Ribosomal, 23S', 'Species Specificity', 'Stochastic Processes'] | 7,529,616 | [['B01.050'], ['G05.045', 'G16.075'], ['D13.444.308'], ['D13.444.308.283.225'], ['B01.050.150.900.649'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500', 'N06.850.520.830.996.500'], ['G05.365.590'], ['D13.444.735.473'], ['D13.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Muscle synergies in preparation to a step made with and without obstacle. | PURPOSE: To study multi-muscle synergies during preparation in making a step (self-paced level stepping vs. obstacle crossing stepping).METHODS: The uncontrolled manifold hypothesis was used to explore the organization of leg and trunk muscles into groups (M-modes) and co-variation of M-mode involvement (M-mode synergi... | ['Adult', 'Electromyography', 'Female', 'Humans', 'Male', 'Movement', 'Muscle Contraction', 'Muscle, Skeletal', 'Postural Balance', 'Posture', 'Psychomotor Performance', 'Reaction Time', 'Young Adult'] | 25,118,841 | [['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G11.561.790.541.595'], ['G11.427.695'], ['F02.808', 'G11.427.700', 'G11.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evidence for transhemispheric diaschisis in unilateral stroke. | Nineteen patients with strictly unilateral ischemic stroke as determined by clinical examination, computed tomography, magnetic resonance imaging, and standard angiography underwent cerebral blood flow (CBF) analysis using fluorine 18 fluoromethane and positron emission tomography. Mean flow values for averaged hemisph... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Brain Ischemia', 'Cerebrovascular Circulation', 'Electrophysiology', 'Functional Laterality', 'Humans', 'Middle Aged', 'Regression Analysis', 'Risk Factors', 'Tomography, Emission-Computed'] | 2,590,018 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G09.330.100.159'], ['H01.158.344.528', 'H01.158.782.236'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.750', 'N05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
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