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Educating future physicians for Ontario: phase II. | In 1990, a collaborative project was launched to determine what the people of Ontario expect of their physicians and how the programs that prepare future physicians should be changed in response. The project, called Educating Future Physicians for Ontario (EFPO), brought together the five Ontario medical schools, the C... | ['Education, Medical', 'Forecasting', 'Humans', 'Internship and Residency', 'Ontario', "Physician's Role", 'Schools, Medical'] | 10,693,841 | [['I02.358.399'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['Z01.107.567.176.639'], ['F01.829.316.616.625.600'], ['I02.783.495.552', 'N02.278.020.578']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Comparison of two assays for the determination of specific IgE in serum of atopic and nonatopic subjects: the Allergenetics FAST and the Phadezym RAST. | The FAST assay (Allergenetics) for the determination of specific IgE has recently been introduced. The results of this test, graded in classes 0 (negative), 1 (equivocal) and 2 to 6 (positive) were compared with those of another commercially available test (Phadezym RAST, Pharmacia), graded from class 0 (negative) and ... | ['Adolescent', 'Adult', 'Allergens', 'Antibody Specificity', 'Evaluation Studies as Topic', 'False Positive Reactions', 'Female', 'Fetal Blood', 'Humans', 'Hypersensitivity, Immediate', 'Immunoglobulin E', 'Infant, Newborn', 'Male', 'Middle Aged', 'Radioallergosorbent Test', 'Radioimmunoassay', 'Skin Tests'] | 3,752,416 | [['M01.060.057'], ['M01.060.116'], ['D23.050.063'], ['G12.100'], ['E05.337', 'N05.715.360.335'], ['E01.354.506'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of school-level and family-level variables on Chinese college students' aggression. | With the frequent occurrence of campus violence, scholars have devoted increasing attention to college students' aggression. This study aims to estimate the prevalence of aggression in Chinese university students and identify factors that could influence their aggression. We can thus find methods to reduce the incidenc... | ['Adolescent', 'Adult', 'Aggression', 'China', 'Family Characteristics', 'Female', 'Humans', 'Incidence', 'Male', 'Prevalence', 'Risk Factors', 'Social Support', 'Students', 'Surveys and Questionnaires', 'Universities', 'Violence', 'Young Adult'] | 27,723,991 | [['M01.060.057'], ['M01.060.116'], ['F01.145.126.125', 'F01.145.813.045'], ['Z01.252.474.164'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Improving efficiency of an angiotensin converting enzyme inhibitory peptide as multifunctional peptides. | Bioactive peptides have been defined as specific protein fragments that have numerous biological activities. The aim of this study was to introduce three multifunctional peptides. Hence, we used rabbit lung angiotensin converting enzyme (ACE) inhibitor peptide AFKDEDTEEVPFR to prepare two analogous peptides KDEDTEEVP a... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Anti-Infective Agents', 'Antioxidants', 'Lipid Peroxidation', 'Models, Molecular', 'Molecular Conformation', 'Peptides', 'Peptidyl-Dipeptidase A', 'Rabbits', 'Spectrum Analysis', 'Structure-Activity Relationship'] | 29,173,094 | [['D27.505.519.389.745.085'], ['B01.050'], ['D27.505.954.122'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G02.111.515', 'G03.295.531.587'], ['E05.599.595'], ['G02.111.570.820'], ['D12.644'], ['D08.811.277.656.350.350.687'], ['B01.050.150.900.649.313.968.700'], ['E05.196.867'], ['G02.111.830', 'G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ethical issues in health care institutions. Lesson Four: Allocation of medical resources. | Health care rationing is the subject of the fourth lesson in a five-part WMU/AHRA magazine course on ethics. Since not every citizen in our country is guaranteed the right to basic health care, there exists a rationing system in which health care is allocated on the basis of ability to pay and need, asserts Dr. Hartlin... | ['Ethics, Institutional', 'Health Care Rationing', 'Health Resources', 'Health Services Needs and Demand', 'United States'] | 10,112,685 | [['K01.752.566.479.168', 'N05.350.325'], ['I01.261.750.500', 'N03.349.270', 'N05.300.430.375'], ['N03.349.340', 'N05.300.420'], ['N03.349.380.420', 'N05.300.450'], ['Z01.107.567.875']] | ['Humanities [K]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
DNA replication is intrinsically hindered in terminally differentiated myotubes. | BACKGROUND: Terminally differentiated (TD) cells permanently exit the mitotic cycle while acquiring specialized characteristics. Although TD cells can be forced to reenter the cell cycle by different means, they cannot be made to stably proliferate, as attempts to induce their replication constantly result in cell deat... | ['Animals', 'Apoptosis', 'Blotting, Western', 'Cell Cycle', 'Cell Differentiation', 'Cell Line', 'Cells, Cultured', 'Comet Assay', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclin-Dependent Kinase Inhibitor p27', 'DNA Replication', 'Fibroblasts', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Mice', 'Mitosis', 'M... | 20,644,635 | [['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144'], ['G04.152'], ['A11.251.210'], ['A11.251'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['D12.644.360.225.500', 'D12.776.157.687.2... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical study on the distribution of neuron-specific enolase-and peptide-containing nerves in the reticulorumen and the reticular groove of cattle. | The distribution of nerves containing immunoreactivity for substance P (SP), vasoactive intestinal polypeptide (VIP), leucine-enkephalin (LENK), gastrin-releasing polypeptide (GRP), and somatostatin (SOM) was studied in the reticulorumen and the reticular groove of the calf and cow, use immunohistochemistry. Neuron-spe... | ['Animals', 'Cattle', 'Enkephalin, Leucine', 'Female', 'Gastrin-Releasing Peptide', 'Immunoenzyme Techniques', 'Nerve Fibers', 'Nerve Tissue Proteins', 'Neurons', 'Peptides', 'Phosphopyruvate Hydratase', 'Somatostatin', 'Stomach, Ruminant', 'Vasoactive Intestinal Peptide'] | 2,873,155 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D12.644.400.575.281.231', 'D12.776.631.650.575.281.231'], ['D06.472.317.410', 'D12.644.400.315', 'D12.776.631.650.315'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A08.675.542', 'A11.671.501'], ['D12.776.631'], ['A08.675', 'A11.671'], ['D12.644'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased epidermal growth factor receptor expression at the invasive margin is a negative prognostic factor in colorectal cancer. | The receptor tyrosine kinase epidermal growth factor receptor (EGFR) is often expressed in solid malignant tumours, and the expression has been correlated to disease progression. Multiple new agents targeted against the EGFR have been developed during the last decade, but treatment selecting criteria are still not clea... | ['Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Colorectal Neoplasms', 'Disease Progression', 'ErbB Receptors', 'Female', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Prognosis', 'Proportional Hazards Models', 'Retrospective Studies'... | 20,635,387 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['C23.550.291.656'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Feline leukaemia virus proviral DNA detected by polymerase chain reaction in antigenaemic but non-viraemic ('discordant') cats. | A nested polymerase chain reaction (PCR) was established to detect exogenous feline leukaemia virus (FeLV) proviral DNA in feline peripheral blood leukocytes (PBL). The assay detected a single copy of plasmid DNA of an infectious molecular clone of FeLV subgroup A in the sample by ethidium bromide staining in agarose g... | ['Animals', 'Cats', 'DNA, Viral', 'Enzyme-Linked Immunosorbent Assay', 'Leukemia Virus, Feline', 'Leukemia, Feline', 'Leukocytes', 'Oligonucleotides', 'Polymerase Chain Reaction'] | 9,125,046 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D13.444.308.568'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B04.613.807.375.500', 'B04.820.650.375.500'], ['C01.925.782.815.622', 'C04.557.337.385', 'C22.180.500'], ['A11.118.63... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adenoviral vector-mediated gene expression in the nervous system of immunocompetent Wistar and T cell-deficient nude rats: preferential survival of transduced astroglial cells in nude rats. | In the present paper, we examined the effect of the adenoviral vector dosage, the role of T cells, and the influence of the presence of replication-competent adenovirus (RCA) in adenoviral vector stocks, on the efficacy of adenoviral vector-directed transgene expression in the facial nucleus of immunocompetent Wistar a... | ['Adenoviridae', 'Animals', 'Astrocytes', 'CD8-Positive T-Lymphocytes', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Facial Nerve', 'Gene Transfer Techniques', 'Genes, Reporter', 'Genetic Vectors', 'Immunocompetence', 'Macrophages', 'Male', 'Motor Neurons', 'Necrosis', 'Nervous System', 'Rats', 'Rats, Nude', '... | 9,189,763 | [['B04.280.030'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['E05.393.3... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Linkage and association of the mitochondrial aspartate/glutamate carrier SLC25A12 gene with autism. | OBJECTIVE: Autism/autistic disorder (MIM number 209850) is a complex, largely genetic psychiatric disorder. The authors recently mapped a susceptibility locus for autism to chromosome region 2q24-q33 (MIM number 606053). In the present study, genes across the 2q24-q33 interval were analyzed to identify an autism suscep... | ['Aspartic Acid', 'Autistic Disorder', 'Chromosome Mapping', 'Chromosomes, Human, Pair 2', 'DNA Mutational Analysis', 'DNA, Mitochondrial', 'Genetic Linkage', 'Genetic Predisposition to Disease', 'Genotype', 'Glutamic Acid', 'Haplotypes', 'Humans', 'Membrane Transport Proteins', 'Mitochondrial Membrane Transport Protei... | 15,056,512 | [['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['F03.625.164.113.500'], ['E05.393.183'], ['A11.284.187.520.300.235.245', 'G05.360.162.520.300.235.245'], ['E05.393.760.700.300'], ['D13.444.308.283.225'], ['G05.348'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['D12.125.067.625.349', 'D12.125.119.4... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An immunofluorescence study of extracellular matrix associated with cytotrophoblast of the chorion laeve. | Using immunofluorescence we have studied the distribution within and beneath the cytotrophoblast of chorion laeve of five extracellular matrix components: types I, III and IV collagen, fibronectin and laminin. Fibronectin, laminin and types I and IV collagen are located in a network of extracellular matrix which encaps... | ['Actins', 'Basement Membrane', 'Chorion', 'Collagen', 'Extracellular Matrix', 'Female', 'Fibronectins', 'Fluorescent Antibody Technique', 'Histocytochemistry', 'Humans', 'Keratins', 'Laminin', 'Plasminogen', 'Pregnancy', 'Trophoblasts'] | 2,425,348 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['A10.272.220', 'A10.615.179'], ['A10.615.284.473', 'A16.254.750.473'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A11.284.295.310'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['E01.370.225.500... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Technique for viral neutralization antibody surveys in primary microcultures. | A simplified, microplate tissue culture procedure is described which facilitates neutralization antibody surveys on large numbers of sera. A comparison of the micromethod with that employing standard tube cultures indicates it to be as sensitive and far more economical. | ['Adenoviridae', 'Animals', 'Antibodies', 'Culture Media', 'Culture Techniques', 'Haplorhini', 'Immune Sera', 'Kidney', 'Methods', 'Neutralization Tests'] | 4,992,659 | [['B04.280.030'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D27.720.470.305', 'E07.206'], ['E05.481.500'], ['B01.050.150.900.649.313.988.400'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hydrogen bond dynamics in primary alcohols: a femtosecond infrared study. | Hydrogen-bonded liquids are excellent solvents, in part due to the highly dynamic character of the directional interaction associated with the hydrogen bond. Here we study the vibrational and reorientational dynamics of deuterated hydroxyl groups in various primary alcohols using polarization-resolved femtosecond infra... | ['Alcohols', 'Hydrogen Bonding', 'Models, Molecular', 'Spectrophotometry, Infrared', 'Time Factors'] | 25,531,023 | [['D02.033'], ['G02.282'], ['E05.599.595'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are i-STAT results adversely affected by an artificial blood substitute in vivo? | The purpose of this study was to determine whether i-STAT measurements on blood treated with hemoglobin-based oxygen carrier-201 (HBOC-201) would provide laboratory test results comparable to those achieved with a known reliable piece of equipment (Radiometer) for swine blood treated with HBOC-201. HBOC-201 is an artif... | ['Animals', 'Blood Substitutes', 'Hematologic Tests', 'Hemoglobins', 'Swine', 'United States', 'Warfare'] | 16,761,886 | [['B01.050'], ['D27.505.954.502.140', 'J01.637.087.249'], ['E01.370.225.625', 'E05.200.625'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.500.880'], ['Z01.107.567.875'], ['I01.880.735.950.500']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 |
Reinstating verbal memories with virtual contexts: Myth or reality? | When learning new information, contextual information about the encoding situation is stored in addition to the focal memory content. Later, these strings of extra information can help retrieve the learned content as demonstrated by experiments where contextual cues from an encoding situation facilitate remembering and... | ['Brain', 'Cues', 'Female', 'Humans', 'Male', 'Mental Recall', 'Visual Perception', 'Young Adult'] | 30,925,185 | [['A08.186.211'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.593.932'], ['M01.060.116.815']] | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Manipulation of membrane protein topology on the endoplasmic reticulum by a specific ligand in living cells. | Almost all integral membrane proteins in the secretory pathway are cotranslationally inserted into the endoplasmic reticulum membrane. Their membrane topology is determined by their amino acid sequences. Here we show that the topology can be manipulated by a factor other than the amino acid sequence. A dihydrofolate re... | ['Amino Acid Sequence', 'Animals', 'COS Cells', 'Chlorocebus aethiops', 'Endoplasmic Reticulum', 'Ligands', 'Membrane Proteins', 'Methotrexate', 'Recombinant Fusion Proteins', 'Tetrahydrofolate Dehydrogenase', 'Transfection', 'Translocation, Genetic'] | 16,272,575 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['A11.284.430.214.190.875.248'], ['D27.720.470.480'], ['D12.776.543'], ['D03.633.100.733.631.192.500'], ['D12.776.828.300'], ['D08.811.682.662.825'], ['E05.393.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Recovery-focused cognitive-behavioural therapy for recent-onset bipolar disorder: randomised controlled pilot trial. | BACKGROUND: Despite evidence for the effectiveness of structured psychological therapies for bipolar disorder no psychological interventions have been specifically designed to enhance personal recovery for individuals with recent-onset bipolar disorder.AIMS: A pilot study to assess the feasibility and effectiveness of ... | ['Adolescent', 'Adult', 'Aged', 'Bipolar Disorder', 'Cognitive Behavioral Therapy', 'Early Medical Intervention', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Compliance', 'Pilot Projects', 'Professional-Patient Relations', 'Single-Blind Method', 'Treatment Outcome', 'Young Adult'] | 25,213,157 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F03.084.500'], ['F04.754.137.350'], ['N02.421.726.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Innervation of the canine thoracolumbar vertebral column. | The pattern of innervation of the caudal thoracic and cranial lumbar vertebral column of the dog is described. Frozen sections stained with Schofield's silver impregnation method show that the dorsal longitudinal ligament is profusely innervated, while the anulus fibrosus contains a few nerves limited to its outermost ... | ['Animals', 'Dogs', 'Female', 'Ganglia, Spinal', 'Horseradish Peroxidase', 'Intervertebral Disc', 'Lumbar Vertebrae', 'Male', 'Spinal Nerves', 'Thoracic Vertebrae'] | 6,711,838 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['D08.811.682.732.512'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['A02.835.232.834.519'], ['A08.800.800.720'], ['A02.835.232.834.892']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional characterization of rat glutaryl-CoA dehydrogenase and its comparison with straight-chain acyl-CoA dehydrogenase. | Glutaryl-CoA dehydrogenase catalyzes the oxidative decarboxylation of the ã-carboxylate of the substrate, glutaryl-CoA, to yield crotonyl-CoA and CO(2). The enzyme is a member of the acyl-CoA dehydrogenase (ACD) family of flavoproteins. In the present study, the catalytic properties of this enzyme, including its substr... | ['Acyl Coenzyme A', 'Amino Acid Sequence', 'Animals', 'Enzyme Inhibitors', 'Glutaryl-CoA Dehydrogenase', 'Molecular Sequence Data', 'Rats', 'Substrate Specificity'] | 21,974,953 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.519.389'], ['D08.811.682.660.425'], ['L01.453.245.667'], ['B01.050.150.900.649.313.992.635.505.700'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Maternal DNA hypomethylation and congenital heart defects. | BACKGROUND: Congenital heart defects (CHDs) are among the most prevalent and serious of birth defects. Multiple maternal factors are thought to contribute to CHD development, including folate intake. Maternal DNA methylation, which is dependent on folate metabolism, may impact the risk of CHDs. Our study was designed t... | ['Case-Control Studies', 'DNA', 'DNA Methylation', 'Eating', 'Female', 'Folic Acid', 'Gene Expression Regulation, Developmental', 'Heart Defects, Congenital', 'Humans', 'Long Interspersed Nucleotide Elements', 'Mothers', 'Polymerase Chain Reaction', 'Pregnancy', 'Risk Factors'] | 21,254,366 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D13.444.308'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G07.203.650.283', 'G10.261.330'], ['D03.633.100.733.631.400'], ['G05.308.310'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.64... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Dissociation of bactericidal activity from other functions of activated macrophages in exudates induced by thioglycolate medium. | Macrophages displayed increased spreading, increased Fc-receptor-mediated phagocytosis, and increased secretion of plasminogen activator when collected from the peritoneal cavities of either Listeria-immune mice challenged intraperitoneally 3 days earlier with Listeria or nonimmune mice injected intraperitoneally 3 day... | ['Agar', 'Animals', 'Cell Movement', 'Colloids', 'Female', 'Listeria monocytogenes', 'Macrophage Activation', 'Macrophages', 'Mice', 'Phagocytosis', 'Plasminogen Activators', 'Thioglycolates'] | 6,795,125 | [['D09.698.360.041'], ['B01.050'], ['G04.198', 'G07.568.500.180'], ['D20.280', 'D26.255.165'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'], ['G12.287.500'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolic evolution of two reducing equivalent-conserving pathways for high-yield succinate production in Escherichia coli. | Reducing equivalents are an important cofactor for efficient synthesis of target products. During metabolic evolution to improve succinate production in Escherichia coli strains, two reducing equivalent-conserving pathways were activated to increase succinate yield. The sensitivity of pyruvate dehydrogenase to NADH inh... | ['Directed Molecular Evolution', 'Escherichia coli', 'Escherichia coli Proteins', 'Metabolic Engineering', 'NAD', 'NADP Transhydrogenase, B-Specific', 'Pentose Phosphate Pathway', 'Pyruvate Dehydrogenase Complex', 'Succinic Acid'] | 24,831,708 | [['E05.393.420.175'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['E05.393.420.526', 'E05.481.500.311.249', 'J01.293.069.249.249'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['D08.811.682.608.540.750', 'D12.776.097.541'], ['G02.111.15... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ficolin-3/adiponectin ratio for the prediction of gestational diabetes mellitus in pregnant women. | AIMS/INTRODUCTION: To establish that the ficolin-3/adiponectin ratio is a predictor for gestational diabetes mellitus (GDM) and is eligible for screening tests for GDM.MATERIALS AND METHODS: A prospective cohort study of 86 pregnant women who developed GDM and 273 normal glucose tolerance participants was carried out. ... | ['Adiponectin', 'Adult', 'Biomarkers', 'Diabetes, Gestational', 'Female', 'Glycoproteins', 'Humans', 'Lectins', 'Pregnancy', 'Prospective Studies', 'Sensitivity and Specificity'] | 28,445,618 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['M01.060.116'], ['D23.101'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.503'], ['G08.686.784.769'], ['... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Roscovitine differentially affects asynchronously growing and synchronized human MCF-7 breast cancer cells. | Roscovitine (ROSC), a selective blocker of cyclin-dependent kinases (CDKs) efficiently inhibits proliferation of exponentially growing human MCF-7 breast cancer cells by induction of cell cycle arrest and p53-mediated apoptosis. ROSC blocks MCF-7 cells in G(2) phase in a time- and concentration-dependent manner. Howeve... | ['Antineoplastic Agents', 'Breast Neoplasms', 'Cell Cycle', 'Cell Division', 'Cell Proliferation', 'Cell Survival', 'Culture Media, Serum-Free', 'Cyclin-Dependent Kinases', 'DNA, Neoplasm', 'Dose-Response Relationship, Drug', 'Female', 'Flow Cytometry', 'G2 Phase', 'Humans', 'Hydroxyurea', 'Protein Kinase Inhibitors', ... | 19,723,062 | [['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['G04.144'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D27.720.470.305.255', 'E07.206.255'], ['D08.811.913.696.620.682.700.646.500', 'D12.644.360.250', 'D12.776.167.200', 'D12... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Problem-solving skills, locus of control, and the contraceptive effectiveness of young women. | It was proposed that the lack of insight into the risk-taking behavior of many sexually active women who do not want to get pregnant may reflect the lack of an adequate framework from which to investigate the problem. The purpose of this study was to examine the relationships between contraceptive effectiveness and sev... | ['Abortion, Induced', 'Adolescent', 'Adult', 'Contraception Behavior', 'Female', 'Humans', 'Internal-External Control', 'Pregnancy', 'Problem Solving'] | 446,211 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2',3'-dideoxycytidine. | To investigate whether human immunodeficiency virus type 1 pol gene mutations are selected during prolonged 2',3'-dideoxycytidine (ddC) therapy, we used the polymerase chain reaction to amplify a portion of the reverse transcriptase segment of the pol gene from the peripheral blood mononuclear cell DNA of a patient wit... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Amino Acid Sequence', 'Base Sequence', 'Drug Resistance, Microbial', 'Genes, pol', 'HIV-1', 'Humans', 'Hybridization, Genetic', 'Male', 'Molecular Sequence Data', 'Mutation', 'Zalcitabine'] | 1,317,143 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G06.225', 'G07.690.773.984.269... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Estrous cycle-dependent neural plasticity in the caudal brainstem in the female golden hamster: ultrastructural and immunocytochemical studies of axo-dendritic relationships and dynamic remodeling. | UNLABELLED: During the short four-day estrous cycle of the female hamster various behavioral (lordosis, vocalization and aggression) and autonomic adaptations occur. Presumably, these changes are under ovarian control. Recently, we described a distinct estrogen receptor-alpha immunoreactive (ER-alpha-IR) cell group, no... | ['Animals', 'Brain Stem', 'Cricetinae', 'Dendrites', 'Estrogen Receptor alpha', 'Estrous Cycle', 'Female', 'Immunohistochemistry', 'Male', 'Mesocricetus', 'Models, Biological', 'Neural Pathways', 'Neuronal Plasticity', 'Ovariectomy', 'Posture', 'Presynaptic Terminals', 'Sexual Behavior, Animal'] | 18,644,374 | [['B01.050'], ['A08.186.211.132'], ['B01.050.150.900.649.313.992.635.075.250'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['D12.776.826.750.350.174'], ['G08.686.195'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Tyrphostin AG490 reduces inflammation and fibrosis in neonatal obstructive nephropathy. | BACKGROUND: Congenital obstructive nephropathy is the main cause of end-stage renal disease in infants and children. Renal insufficiency is due to impaired growth and maturation in the developing kidney with obstruction. Congenital obstructive nephropathy leads to cytokine mediated inflammation and the development of i... | ['Animals', 'Animals, Newborn', 'Enzyme Inhibitors', 'Fibrosis', 'Inflammation', 'Janus Kinase 2', 'Mice', 'STAT3 Transcription Factor', 'Tyrphostins', 'Ureteral Obstruction'] | 31,846,485 | [['B01.050'], ['B01.050.050.282'], ['D27.505.519.389'], ['C23.550.355'], ['C23.550.470'], ['D08.811.913.696.620.682.725.124.200', 'D12.776.476.393.200', 'D12.776.624.664.700.117'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.360.024.342.300', 'D12.776.157.057.186.300', 'D12.776.476.024.430.300', 'D12.776.930... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analytical derivation of thermodynamic characteristics of lipid bilayer from a flexible string model. | We introduce a flexible string model of the hydrocarbon chain and derive an analytical expression for the lateral pressure profile across the hydrophobic core of the membrane. The pressure profile influences the functioning of the embedded proteins and is difficult to measure experimentally. In our model the hydrocarbo... | ['Compressive Strength', 'Computer Simulation', 'Elasticity', 'Hydrophobic and Hydrophilic Interactions', 'Lipid Bilayers', 'Membrane Fluidity', 'Models, Chemical', 'Models, Molecular', 'Molecular Conformation', 'Pressure', 'Stress, Mechanical', 'Temperature', 'Thermodynamics'] | 16,089,776 | [['G01.374.180'], ['L01.224.160'], ['G01.374.590'], ['G02.409'], ['D10.570.510', 'J01.637.087.500.510'], ['G01.154.500', 'G02.111.550', 'G04.570'], ['E05.599.495'], ['E05.599.595'], ['G02.111.570.820'], ['G01.374.715'], ['G01.374.835'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Effects of sodium citrate on salt sensitivity and kidney injury in chronic renal failure. | Metabolic acidosis, which is observed in salt-sensitive hypertension, is also associated with kidney injury. Alkali therapy in chronic renal failure (CRF) may ameliorate the progression of kidney disease; however, few studies have examined the effects of alkali therapy on salt sensitivity and kidney injury in CRF. We r... | ['Acute Kidney Injury', 'Administration, Oral', 'Animals', 'Citrates', 'Dietary Supplements', 'Kidney Failure, Chronic', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Salt Tolerance', 'Sodium Citrate', 'Treatment Outcome'] | 25,469,066 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['E02.319.267.100'], ['B01.050'], ['D02.241.081.901.434'], ['G07.203.300.456', 'J02.500.456'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G07.025.133.250'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Use of antibiotic disks to evolve drug-resistant bacteria. | The methods used to generate antibiotic-resistant bacterial strains can be labour-intensive, costly, lengthy and/or prone to plate-to-plate variation. We propose a simple, inexpensive and easily replicated method to expose bacteria to a continuous gradient of antibiotic concentration, providing an environment of positi... | ['Adaptation, Biological', 'Anti-Bacterial Agents', 'Biological Evolution', 'Burkholderia cepacia complex', 'Drug Resistance, Bacterial', 'Microbial Sensitivity Tests'] | 29,497,870 | [['G16.012'], ['D27.505.954.122.085'], ['G05.045', 'G16.075'], ['B03.660.075.090.688.100.110'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seasonal changes in NRF2 antioxidant pathway regulates winter depression-like behavior. | Seasonal changes in the environment lead to depression-like behaviors in humans and animals. The underlying mechanisms, however, are unknown. We observed decreased sociability and increased anxiety-like behavior in medaka fish exposed to winter-like conditions. Whole brain metabolomic analysis revealed seasonal changes... | ['Animals', 'Behavior, Animal', 'Depression', 'Dimethyl Sulfoxide', 'Gene Expression Regulation', 'Genome', 'Mutation', 'NF-E2-Related Factor 2', 'Oryzias', 'Seasons'] | 32,277,035 | [['B01.050'], ['F01.145.113'], ['F01.145.126.350'], ['D02.886.640.150'], ['G05.308'], ['G05.360.340'], ['G05.365.590'], ['D12.776.260.108.737', 'D12.776.930.127.737'], ['B01.050.150.900.493.850.139.650'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
P/Ca in coral skeleton as a geochemical proxy for seawater phosphorus variation in Daya Bay, northern South China Sea. | The P/Ca ratio in coral skeletons is considered to be a direct proxy for the nutrient P in seawater. We examined the reliability of this proxy by analyzing P/Ca in a Porites coral collected from a eutrophic area in the northern South China Sea. P concentrations were significantly higher compared to previously reported ... | ['Animals', 'Anthozoa', 'Bays', 'Calcium', 'China', 'Coral Reefs', 'Environmental Monitoring', 'Phosphorus', 'Water Pollutants, Chemical'] | 21,820,683 | [['B01.050'], ['B01.050.500.308.237'], ['G01.311.625.080'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['Z01.252.474.164'], ['G16.500.275.157.130', 'N06.230.124.130'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.268.666'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effects of polyphenol-rich chokeberry juice on antioxidant/pro-oxidant status in healthy subjects. | Berry fruits are a rich source of polyphenols, especially anthocyanins: well-known potent anti-oxidant phytochemicals. The purpose of this study was to evaluate beneficial effects of long-term consumption of polyphenol-rich organic chokeberry juice on different markers of antioxidant/pro-oxidant status in healthy femal... | ['Adult', 'Antioxidants', 'Beverages', 'Blood Pressure', 'Female', 'Food, Organic', 'Fruit', 'Healthy Volunteers', 'Humans', 'Middle Aged', 'Oxidants', 'Oxidative Stress', 'Polyphenols', 'Prunus', 'Reactive Oxygen Species', 'Thiobarbituric Acid Reactive Substances'] | 24,650,155 | [['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.203.100', 'J02.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.203.300.519', 'J02.500.519'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
The 6 dimensions of promising practice for case managed supports to end homelessness: part 2: the 6 dimensions of quality. | PURPOSE/OBJECTIVES: Homelessness is a social condition increasing in frequency and severity across Canada. Interventions to end and prevent homelessness include effective case management in addition to an affordable housing provision. Little standardization exists for service providers to guide their decision making in... | ['Canada', 'Case Management', 'Cooperative Behavior', 'Delivery of Health Care', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Homeless Persons', 'Humans', 'Models, Theoretical', 'Patient Care Team', 'Patient-Centered Care', "Practice Patterns, Physicians'", 'Professional Competence', 'Quality o... | 22,146,635 | [['Z01.107.567.176'], ['N04.590.233.624.250'], ['F01.145.813.115'], ['N04.590.374', 'N05.300'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['M01.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['N04.590.715'], ['N04.590.233.727.407'], ['N04.590.374.577', 'N05.300.625'],... | ['Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Catatonia in adolescents: series of 12 inpatients. | BACKGROUND: Catatonia is one of the most severe psychiatric syndromes that might be caused by many medical as well as psychiatric conditions. Catatonia in adolescents is rare and largely understudied.AIMS: This papers aims to examine cases of catatonia among adolescent psychiatric inpatients, and to scrutinize both the... | ['Adolescent', 'Catatonia', 'Child', 'Female', 'Hospitalization', 'Humans', 'Male', 'Retrospective Studies', 'Tunisia'] | 26,815,523 | [['M01.060.057'], ['C10.597.606.115', 'C23.888.592.604.115', 'F01.145.126.156', 'F01.700.165'], ['M01.060.406'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Phylum-wide analysis of genes/proteins related to the last steps of assembly and export of extracellular polymeric substances (EPS) in cyanobacteria. | Many cyanobacteria produce extracellular polymeric substances (EPS) with particular characteristics (e.g. anionic nature and presence of sulfate) that make them suitable for industrial processes such as bioremediation of heavy metals or thickening, suspending or emulsifying agents. Nevertheless, their biosynthetic path... | ['ATP-Binding Cassette Transporters', 'Amino Acid Sequence', 'Bacterial Proteins', 'Carrier Proteins', 'Extracellular Space', 'Gene Expression Regulation, Bacterial', 'Genome, Bacterial', 'Ligases', 'Macromolecular Substances', 'Molecular Sequence Data', 'Phylogeny', 'Prochlorococcus', 'Sequence Alignment', 'Synechococ... | 26,437,902 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D12.776.157'], ['A10.082.500', 'A11.284.295'], ['G05.308.300'], ['G05.360.340.358.207'], ['D08.811.464'], ['D05'], ['L01.453.245.667'], ['G05.697', 'G16.075.605',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Needlestick injuries among nursing staff: association with shift-level staffing. | BACKGROUND: Despite the advent of safety measures to protect the health care workforce from contracting blood-borne diseases, nurses still sustain percutaneous injuries. We investigated the association between shift-level staffing and needlestick injuries.METHODS: Shift-level staffing, patient occupancy, and acuity dat... | ['Humans', 'Needlestick Injuries', 'Nursing Staff', 'Prevalence', 'Risk Factors'] | 21,612,843 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.986.950.500'], ['M01.526.485.680', 'N02.360.680'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Ultrasonic diagnosis of deep venous thrombosis. A comparison with venography]. | In a prospective study ultrasonography (US) was compared with venography for diagnosis of deep venous thrombosis of the leg. Using venography, thrombosis was demonstrated in 25 patients. Based on two criteria, non-compressible vein and intraluminal echoes, US showed thrombosis in 23 patients, i.e. the sensitivity was 9... | ['Adolescent', 'Adult', 'Aged', 'Costs and Cost Analysis', 'Female', 'Femoral Vein', 'Humans', 'Male', 'Middle Aged', 'Norway', 'Prospective Studies', 'Radiography', 'Thrombosis', 'Ultrasonography'] | 2,683,195 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N03.219.151'], ['A07.015.908.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.816.374'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.370.350.700'], ['C14.907.355.830'], ['... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Filarial infection influences mosquito behaviour and fecundity. | Understanding vector-parasite interactions is increasingly important as we move towards the endpoint goals set by the Global Programme for the Elimination of Lymphatic Filariasis (GPELF), as interaction dynamics may change with reduced transmission pressure. Elimination models used to predict programmatic endpoints inc... | ['Aedes', 'Animals', 'Behavior, Animal', 'Brugia malayi', 'Elephantiasis, Filarial', 'Female', 'Humans', 'Insect Vectors', 'Larva', 'Mosquito Control'] | 27,796,352 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['F01.145.113'], ['B01.050.500.500.294.400.937.463.088.500'], ['C01.610.335.508.700.750.361.350', 'C01.920.750', 'C15.604.496.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['B05.5... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of intravaginal misoprostol and intracervical Foley catheter alone or in combination for termination of second trimester pregnancy. | OBJECTIVES: To examine the effectiveness, safety and acceptability of intravaginal misoprostol and intracervical Foley catheter alone or in combination for termination of second trimester pregnancy.METHODS: This clinical study was conducted on 90 pregnant patients intended for termination of pregnancy between 13 and 24... | ['Abortifacient Agents, Nonsteroidal', 'Abortion, Induced', 'Adult', 'Catheterization', 'Female', 'Humans', 'Misoprostol', 'Pregnancy', 'Pregnancy Trimester, Second', 'Prospective Studies', 'Young Adult'] | 24,635,496 | [['D27.505.696.875.131.100', 'D27.505.954.705.131.100'], ['E04.520.050'], ['M01.060.116'], ['E02.148', 'E05.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.251.355.255.550.775.450.500', 'D23.469.050.175.725.775.450.500', 'D23.469.700.660.500'], ['G08.686.784.769'], ['G08.686.707.490'], ['E05.318.372.500.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The radiological diagnosis of meningiomas, the impact of EMI scanning. | A review of the impact of computerized axial tomography on the radiological diagnosis of meningiomas is presented. Seventy-one intracranial and eight orbital cases have been examined by this new method using the 160 X 160 matrix. The diagnostic accuracy of the method is compared with established neuroradiological metho... | ['Angiography', 'Brain Neoplasms', 'Cerebellopontine Angle', 'Diagnosis, Differential', 'Humans', 'Iothalamic Acid', 'Meningioma', 'Neurilemmoma', 'Orbital Neoplasms', 'Pneumoradiography', 'Radiographic Image Enhancement', 'Radionuclide Imaging', 'Tomography, X-Ray Computed'] | 299,819 | [['E01.370.350.700.060', 'E01.370.370.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A08.186.211.132.810.428.200.462'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.400.880.430', 'D02.455.426.559.389.127.375.880.430'], ['C04.557.580.520', 'C04.557.645.520', 'C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevalence, Enterotoxin Genes, and Antibiotic Resistance of Bacillus cereus Isolated from Raw Vegetables in Korea. | Bacillus cereus has long been recognized as an important pathogen in foodborne poisoning worldwide. Fresh vegetables are often contaminated with enterotoxigenic B. cereus and have been implicated as a vehicle for the transmission of this bacterium. This study reports on the occurrence, virulence gene profile, and antib... | ['Bacillus cereus', 'Drug Resistance, Microbial', 'Enterotoxins', 'Food Microbiology', 'Prevalence', 'Republic of Korea', 'Vegetables'] | 30,169,119 | [['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218.252'], ['G06.225', 'G07.690.773.984.269'], ['D23.946.330'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Reconstruction of the acne-scarred face. | The acne-scarred face presents a challenge to the reconstructive surgeon. Dermaplaning technic with the Castro-viejo Electrokeratome ("C-V Planner") results in precise leveling of the skin. Numerous deep pit scars are amenable to small excisions; extensive milk-cheek scarring is treatable by segmental excision and reco... | ['Acne Vulgaris', 'Cicatrix', 'Dermabrasion', 'Dermatologic Surgical Procedures', 'Face', 'Humans', 'Surgery, Plastic'] | 141,468 | [['C17.800.030.150', 'C17.800.794.111'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['E02.218.210', 'E04.680.275.250'], ['E04.680.275'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.788']] | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevention of axonal injury using calpain inhibitor in chronic progressive experimental autoimmune encephalomyelitis. | Axonal injury is the major correlate of permanent disability in neurodegenerative diseases such as multiple sclerosis (MS), especially in secondary-progressive MS which follows relapsing-remitting disease course. Proteolytic enzyme, calpain, is a potential candidate for causing axonal injury. Most current treatment opt... | ['Analysis of Variance', 'Animals', 'Axons', 'Calpain', 'Disease Models, Animal', 'Encephalomyelitis, Autoimmune, Experimental', 'Glycoproteins', 'Leupeptins', 'Mice', 'Mice, Inbred C57BL', 'Myelin Proteins', 'Myelin-Associated Glycoprotein', 'Myelin-Oligodendrocyte Glycoprotein', 'NAV1.6 Voltage-Gated Sodium Channel',... | 18,725,211 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D08.811.277.656.262.500.120', 'D08.811.277.656.300.200.120'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Uncoupling endothelial nitric oxide synthase is ameliorated by green tea in experimental diabetes by re-establishing tetrahydrobiopterin levels. | The current study investigated the potential of green tea (GT) to improve uncoupling of endothelial nitric oxide synthase (eNOS) in diabetic conditions. In rats with streptozotocin-induced diabetes, nitric oxide (NO) bioavailability was reduced by uncoupling eNOS, characterized by a reduction in tetrahydrobiopterin (BH... | ['Animals', 'Antioxidants', 'Biopterin', 'Camellia sinensis', 'Cells, Cultured', 'Diabetes Mellitus, Experimental', 'GTP Cyclohydrolase', 'Humans', 'Mesangial Cells', 'Nitric Oxide', 'Nitric Oxide Synthase Type III', 'Oxidative Stress', 'Rats', 'Rats, Inbred SHR', 'Reactive Oxygen Species', 'Tea'] | 22,586,583 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.633.100.733.631.202', 'D08.211.090'], ['B01.650.940.800.575.912.250.341.998.500.500'], ['A11.251'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D08.811.277.151.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Chemical warfare. Cutaneous lesions from mustard gas. | Cutaneous lesions of eight patients evacuated from the Iran-Iraq war zone are reported. The patients were exposed to mustard gas, and there was a spectrum of dermatologic lesions. In the mild cases only there was a sunburnlike erythema, but in the most severe cases this erythema was followed by large and disseminated b... | ['Adolescent', 'Adult', 'Burns, Chemical', 'Chemical Warfare', 'Epidermis', 'Erythema', 'Female', 'Humans', 'Iran', 'Iraq', 'Male', 'Mustard Compounds', 'Mustard Gas', 'Necrosis', 'Skin Diseases, Vesiculobullous', 'Skin Pigmentation'] | 3,049,698 | [['M01.060.057'], ['M01.060.116'], ['C26.200.156'], ['I01.880.735.950.500.340'], ['A10.272.497', 'A17.815.250'], ['C17.800.229', 'C23.888.885.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['Z01.252.245.500.360'], ['D02.455.526.728'], ['D02.455.526.728.468'], ['C23.550.717'], ['C17.800... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Technical complications of Roux-en-Y gastrojejunostomy. | The Roux-en-Y gastrojejunostomy has become an increasingly popular technique for gastrointestinal tract reconstruction since it is purported to obviate many of the classic complications of the Billroth II gastrojejunostomy. In a review of over 900 Roux-en-Y gastrojejunostomies, seven patients with complications mimicki... | ['Adult', 'Afferent Loop Syndrome', 'Aged', 'Biliary Tract Diseases', 'Blind Loop Syndrome', 'Duodenum', 'Female', 'Gastritis', 'Gastroenterostomy', 'Humans', 'Intestinal Fistula', 'Jejunum', 'Middle Aged', 'Postoperative Complications', 'Radiography', 'Time Factors'] | 6,870,523 | [['M01.060.116'], ['C06.405.469.531.099', 'C23.550.767.050'], ['M01.060.116.100'], ['C06.130'], ['C06.405.469.637.145', 'C18.452.603.145'], ['A03.556.124.684.124', 'A03.556.875.249'], ['C06.405.205.697', 'C06.405.748.398'], ['E04.035.398', 'E04.210.457'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.267.550',... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Euglena gracilis DNA dependent RNA polymerase II: a zinc metalloenzyme. | Zinc is essential for cellular proliferation. Zinc deficiency of Euglena gracilis results in arrest of cell division and deranges nucleic acid and protein metabolism pointing to a decisive role of zinc in transcription and translation. We have, therefore, investigated the role of zinc in the function of the DNA-depende... | ['Amanitins', 'Animals', 'Chelating Agents', 'Copper', 'DNA Polymerase II', 'DNA-Directed DNA Polymerase', 'Euglena gracilis', 'Iron', 'Kinetics', 'Metalloproteins', 'Molecular Weight', 'Phenanthrolines', 'RNA Polymerase II', 'Zinc'] | 823,963 | [['D04.345.566.050', 'D12.644.456.050', 'D12.644.641.050', 'D23.946.587.175'], ['B01.050'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D08.811.913.696.445.308.300.230'], ['D08.811.913.696.445.308.300'], ['B01.268.250.320.418'], ['D01.268.556.412', 'D01.268.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electromechanical coupling of waves in nerve fibres. | The propagation of an action potential (AP) in a nerve fibre is accompanied by mechanical and thermal effects. In this paper, an attempt is made to build up a mathematical model which couples the AP with a possible pressure wave (PW) in the axoplasm and waves in the nerve fibre wall (longitudinal-LW and transverse-TW) ... | ['Action Potentials', 'Axons', 'Computer Simulation', 'Elasticity', 'Humans', 'Ions', 'Lipid Bilayers', 'Models, Theoretical', 'Nerve Fibers', 'Neurons', 'Pressure', 'Stress, Mechanical'] | 30,032,474 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['L01.224.160'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497'], ['D10.570.510', 'J01.637.087.500.510'], ['E05.599'], ['A08.675.542', 'A11.671.501'], ['A08... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Nonglomic tumors of the jugular foramen: differential diagnosis and prognostic implications. | OBJECTIVE: Tumors of the jugular foramen are notably rare, and the majority of them arise from the glomic tissue of the jugular vein. There are other tumors that do not originate from that tissue, and these are called the nonglomic tumors. This report includes a series of patients with nonglomic tumors of the jugular f... | ['Adult', 'Aged', 'Combined Modality Therapy', 'Cross-Sectional Studies', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Glomus Jugulare Tumor', 'Humans', 'Male', 'Middle Aged', 'Neurosurgical Procedures', 'Prognosis', 'Retrospective Studies', 'Skull Base Neoplasms', 'Treatment Outcome', 'Young Adult'] | 25,045,790 | [['M01.060.116'], ['M01.060.116.100'], ['E02.186'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.557.465.625.650.700.705.340', 'C04.557.580.625.650.700.705.340'], ['B01.050.150... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
1,8-Cineol inhibits nuclear translocation of NF-êB p65 and NF-êB-dependent transcriptional activity. | Natural plant-derived products are commonly applied to treat a broad range of human diseases, including cancer as well as chronic and acute airway inflammation. In this regard, the monoterpene oxide 1,8-cineol, the active ingredient of the clinically approved drug Soledum®, is well-established for the therapy of airway... | ['Cell Nucleus', 'Cell Proliferation', 'Cyclohexanols', 'Eucalyptol', 'Gene Expression Regulation, Neoplastic', 'Genes, Reporter', 'HeLa Cells', 'Humans', 'I-kappa B Kinase', 'I-kappa B Proteins', 'JNK Mitogen-Activated Protein Kinases', 'Leukocytes, Mononuclear', 'Lipopolysaccharides', 'Models, Biological', 'Monoterpe... | 23,872,422 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['D02.033.415.510.500.454', 'D02.455.426.392.368.367.318.625', 'D02.455.849.575.250', 'D10.289.510.500.454'], ['G05.308.370'], ['G05.360.340.024.340.435... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Malignant phyllodes tumour with intraductal and invasive carcinoma and lymph node metastasis. | Phyllodes tumours constitute 2-3 percent of fibroepithelial breast tumours, with a 1-2 percent rate of malignancy. Metastasis is usually haematogeneous, and axillary lymph node dissection is not routinely performed. Carcinoma in a phyllodes tumour is distinctly uncommon, but has been known to occur in benign phyllodes ... | ['Breast', 'Breast Neoplasms', 'Carcinoma', 'Female', 'Humans', 'Immunohistochemistry', 'Lymph Nodes', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Phyllodes Tumor', 'Treatment Outcome'] | 19,037,540 | [['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.12... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Studies on the mechanism of the vasodilator effects of prazosin in dogs and rabbits. | In pentobarbital (35.0 mg/kg) anaesthetised dogs, bolus injections of prazosin into the femoral artery (3.0--300.0 microgram) provoked a dose-related fall in the vascular resistance of the innervated hind limb. In contrast to papaverine, prazosin failed to produce the same effect in dogs under spinal anaesthesia even w... | ['Adrenergic alpha-Agonists', 'Animals', 'Aorta', 'Blood Pressure', 'Calcium', 'Dogs', 'Female', 'Heart', 'Heart Rate', 'In Vitro Techniques', 'Male', 'Norepinephrine', 'Potassium', 'Prazosin', 'Quinazolines', 'Rabbits', 'Regional Blood Flow', 'Sympathetic Nervous System', 'Vasodilator Agents'] | 26,580 | [['D27.505.519.625.050.100.100', 'D27.505.696.577.050.100.100'], ['B01.050'], ['A07.015.114.056'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E05.481'], ['D02.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CD4 T cell cooperation is required for the in vivo activation of CD4 T cells. | We address here the role of CD4 T cell cooperation in the activation of CD4 T cells. Administration of aggregated hen egg lysozyme (HEL) without microbial adjuvant to BALB/c mice normally generates cytokine-producing CD4 T cells specific for the HEL major peptide, HEL(105-120), as well as CD4 T cells specific for HEL n... | ['Animals', 'Antigen Presentation', 'CD4-Positive T-Lymphocytes', 'CD40 Antigens', 'Interferon-gamma', 'Interleukin-2', 'Interleukin-4', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred BALB C', 'Muramidase', 'Ovalbumin', 'Peptides', 'T-Lymphocytes, Regulatory'] | 19,736,293 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101.100.150.140'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activated á2-macroglobulin induces M?ller glial cell migration by regulating MT1-MMP activity through LRP1. | In retinal proliferative diseases, M?ller glial cells (MGCs) acquire migratory abilities. However, the mechanisms that regulate this migration remain poorly understood. In addition, proliferative disorders associated with enhanced activities of matrix metalloprotease 2 (MMP-2) and MMP-9 also present increased levels of... | ['Carrier Proteins', 'Cell Line', 'Cell Membrane', 'Cell Movement', 'Endocytosis', 'Endosomes', 'Glutathione Transferase', 'Humans', 'Immunoblotting', 'Low Density Lipoprotein Receptor-Related Protein-1', 'Luminescent Proteins', 'Matrix Metalloproteinase 14', 'Microscopy, Confocal', 'Models, Biological', 'Mutation', 'N... | 23,640,058 | [['D12.776.157'], ['A11.251.210'], ['A11.284.149'], ['G04.198', 'G07.568.500.180'], ['G04.417'], ['A11.284.430.214.190.875.190.880.337'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['D12.776.526.100', 'D12.776.543.750.710.450.500.100'], ['D12.776.53... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical evaluation of Oxoid Brilliance MRSA Agar in comparison with bioMerieux MRSA ID medium for detection of livestock-associated meticillin-resistant Staphylococcus aureus. | Oxoid Brilliance MRSA Agar and bioM?rieux MRSA ID medium were evaluated for their ability to identify meticillin-resistant Staphylococcus aureus (MRSA) in clinical samples. Nasal and throat samples (n = 629) were taken from veterinarians and their household members. The sensitivities of Brilliance MRSA Agar and MRSA ID... | ['Animals', 'Anti-Bacterial Agents', 'Culture Media', 'Humans', 'Livestock', 'Methicillin', 'Methicillin Resistance', 'Methicillin-Resistant Staphylococcus aureus', 'Nose', 'Occupational Diseases', 'Occupational Exposure', 'Pharynx', 'Sensitivity and Specificity', 'Staphylococcal Infections', 'Swine', 'Veterinarians'] | 21,415,201 | [['B01.050'], ['D27.505.954.122.085'], ['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.050.116.500'], ['D02.065.589.099.750.500', 'D02.886.108.750.500', 'D03.633.100.300.750.500'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Paired associative stimulation induces change in presynaptic inhibition of Ia terminals in wrist flexors in humans. | Enhancements in the strength of corticospinal projections to muscles are induced in conscious humans by paired associative stimulation (PAS) to the motor cortex. Although most of the previous studies support the hypothesis that the increase of the amplitude of motor evoked potentials (MEPs) by PAS involves long-term po... | ['Adult', 'Analysis of Variance', 'Area Under Curve', 'Biophysics', 'Electric Stimulation', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'H-Reflex', 'Humans', 'Male', 'Middle Aged', 'Neural Inhibition', 'Presynaptic Terminals', 'Transcranial Magnetic Stimulation', 'Wrist', 'Young Adult'] | 20,538,768 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['H01.158.344', 'H01.671.100'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['G11.561.731.643.47... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of biologically active porcine secretin and [ITyr10] porcine secretin. | Porcine secretin, [Tyr10] secretin, and [Tyr13] secretin were synthesized by solid phase methodology and purified by stepwise gradient elution from a short reversed-phase column with ethanol and acetic acid as organic modifiers. [Tyr10] secretin and [Tyr13] secretin were iodinated by the chloramine-T method and nonmono... | ['Amino Acid Sequence', 'Animals', 'Chromatography, High Pressure Liquid', 'Cyclic AMP', 'Insulin', 'Mice', 'Molecular Sequence Data', 'Radioimmunoassay', 'Secretin', 'Swine'] | 1,651,289 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.181.400.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['E01.370... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Yeast cells recover from mating pheromone alpha factor-induced division arrest by desensitization in the absence of alpha factor destruction. | Saccharomyces cerevisiae MATa cells arrest cell division in response to the mating pheromone, alpha factor. After some interval of time the cells resume division. It is demonstrated here that cells recover from division arrest by becoming insensitive to the alpha factor under conditions of low cell density (10(2) cells... | ['Cell Division', 'Kinetics', 'Mating Factor', 'Peptides', 'Perfusion', 'Saccharomyces cerevisiae'] | 6,363,399 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G01.374.661', 'G02.111.490'], ['D12.644.368', 'D23.641.200'], ['D12.644'], ['E05.680'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recovery and recurrence of left ventricular systolic dysfunction in patients with idiopathic dilated cardiomyopathy. | BACKGROUND: Some patients with nonischemic left ventricular (LV) systolic failure recover to have normal LV systolic function. However, few studies on the rates of recovery and recurrence have been reported, and no definitive indicators that can predict the recurrence of LV dysfunction in recovered idiopathic dilated c... | ['Adult', 'Aged', 'Cardiac Catheterization', 'Cardiomyopathy, Dilated', 'Cardiotonic Agents', 'Cohort Studies', 'Echocardiography, Doppler', 'Electrocardiography', 'Female', 'Heart Failure, Systolic', 'Heart Function Tests', 'Humans', 'Kaplan-Meier Estimate', 'Logistic Models', 'Male', 'Middle Aged', 'Monitoring, Physi... | 19,417,864 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['D27.505.954.411.222', 'D27.720.799.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.130.750.220', 'E01.370.350.850... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Is cryosurgery a feasible local therapy for bone metastatic prostate cancer? | INTRODUCTION: This study aims to assess whether cryosurgery is a feasible local therapy for bone metastatic prostate cancer (bmPCa).METHODS: A total of 23 patients with bmPCa who received cryosurgery and adjuvant androgen deprivation therapy (ADT) were included in the cryosurgery group (Group 1). Another 23 matched pat... | ['Aged', 'Biopsy', 'Bone Neoplasms', 'Cryosurgery', 'Disease Progression', 'Humans', 'Kallikreins', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prostate', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Retrospective Studies', 'Time Factors', 'Treatment Outcome'] | 30,246,213 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.588.149', 'C05.116.231'], ['E04.014.180'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.442', 'D08... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A blinded, randomized controlled evaluation of an impedance threshold device during cardiopulmonary resuscitation in swine. | BACKGROUND: An impedance threshold device (ITD) has been designed to enhance circulation during CPR. A recent study suggests that the ITD does not improve hemodynamics and that it may actually worsen outcomes. We sought to independently assess the effect of the ITD on coronary perfusion pressure (CPP) and passive venti... | ['Animals', 'Cardiopulmonary Resuscitation', 'Coronary Circulation', 'Electric Impedance', 'Male', 'Random Allocation', 'Swine', 'Ventricular Fibrillation'] | 18,308,451 | [['B01.050'], ['E02.365.647.110'], ['G09.330.100.324'], ['G01.358.500.249.277.350'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.500.880'], ['C14.280.067.922', 'C23.550.073.922']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ethylene oligomerization promoted by chromium complexes bearing pyrrolide-imine-amine/ether tridentate ligands. | Chromium(iii) complexes [CrCl2(L)(THF)] based on monoanionic tridentate ligands [, L = {2-(C4H3N-2'-CH[double bond, length as m-dash]N)C2H4NHPh}; , L = {5-tert-butyl-2-(C4H2N-2'-CH[double bond, length as m-dash]N)C2H3NHPh}; , L = {2-(C4H3N-2'-CH[double bond, length as m-dash]N)C2H4OPh}] have been prepared. Complexes an... | ['Amines', 'Chromium', 'Ethers', 'Ethylenes', 'Imines', 'Ligands', 'Models, Molecular', 'Molecular Structure', 'Organometallic Compounds', 'Pyrroles'] | 26,287,598 | [['D02.092'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D02.355'], ['D02.455.326.271.367'], ['D02.491'], ['D27.720.470.480'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D02.691'], ['D03.383.129.578']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bone manganese as a biomarker of manganese exposure: a feasibility study. | BACKGROUND: There is a need for a diagnostic tool with the ability to measure cumulative exposure to manganese (Mn) in the workplace. Measuring bone Mn levels with in vivo neutron activation analysis (IVNAA) could serve as a biomarker of past exposure. Bone Mn levels of welders were measured and compared to the levels ... | ['Adult', 'Aged', 'Biomarkers', 'Bone and Bones', 'Case-Control Studies', 'Feasibility Studies', 'Humans', 'Male', 'Manganese', 'Middle Aged', 'Occupational Exposure', 'Statistics, Nonparametric', 'Welding'] | 19,753,565 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['A02.835.232', 'A10.165.265'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.484', 'D01.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
A mutation in GroEL interferes with protein folding by reducing the rate of discharge of sequestered polypeptides. | GroEL140, a mutant Escherichia coli chaperonin unable to support bacteriophage lambda head assembly, was purified to near homogeneity and compared to wild type GroEL (cpn60). GroEL140 exhibited a 1.5-fold lower ATPase activity relative to the wild type protein. The hydrolysis of ATP by both polypeptides was fully inhib... | ['Adenine Nucleotides', 'Adenosine Triphosphatases', 'Bacterial Proteins', 'Chaperonin 60', 'Chromatography, Gel', 'Escherichia coli', 'Heat-Shock Proteins', 'Hydrolysis', 'Mutation', 'Plasmids', 'Protein Conformation', 'Ribulose-Bisphosphate Carboxylase', 'Trypsin'] | 1,350,786 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D08.811.277.040.025'], ['D12.776.097'], ['D08.811.277.040.025.142.500.500', 'D12.776.580.216.210.590.750'], ['E05.196.181.400.250'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.580.216'], ['G02.380'], ['G05.365.590'], ['G05.360.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molybdate binding by ModA, the periplasmic component of the Escherichia coli mod molybdate transport system. | ModA, the periplasmic-binding protein of the Escherichia coli mod transport system was overexpressed and purified. Binding of molybdate and tungstate to ModA was found to modify the UV absorption and fluorescence emission spectra of the protein. Titration of these changes showed that ModA binds molybdate and tungstate ... | ['Bacterial Proteins', 'Biological Transport', 'Carrier Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Molybdenum', 'Molybdoferredoxin', 'Periplasm', 'Periplasmic Binding Proteins', 'Protein Binding', 'Radioligand Assay', 'Spectrometry, Fluorescence', 'Spectrophotometry, Ultraviolet', 'Tungsten Compounds'... | 9,545,596 | [['D12.776.097'], ['G03.143'], ['D12.776.157'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['D08.811.682.647.550', 'D12.776.097.350.450', 'D12.776.157.427.374.375.275.450', 'D12.776.556.579.374.375.275.450'], ['A11.284.295.680'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Locus specificity of polymorphic alleles and evolution by a birth-and-death process in mammalian MHC genes. | We have conducted an extensive phylogenetic analysis of polymorphic alleles from human and mouse major histocompatibility complex (MHC) class I and class II genes. The phylogenetic tree obtained for 212 complete human class I allele sequences (HLA-A, -B, and -C) has shown that all alleles from the same locus form a sin... | ['Alleles', 'Animals', 'Evolution, Molecular', 'Gene Conversion', 'Genes, MHC Class I', 'Genes, MHC Class II', 'HLA-B Antigens', 'Humans', 'Mice', 'Phylogeny', 'Point Mutation', 'Polymorphism, Genetic', 'Recombination, Genetic'] | 10,028,282 | [['G05.360.340.024.340.030'], ['B01.050'], ['G05.045.250', 'G16.075.250'], ['G05.728.615.475'], ['G05.360.340.024.340.610.595', 'G05.360.340.024.380.500.595', 'G12.500.500.595'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['D12.776.395.550.489.500', 'D12.776.543.550.439.500', 'D2... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intravenous propofol anaesthesia using a computerised infusion system. | Propofol offers many advantages as a total intravenous anaesthetic agent compared with other agents. However, considerable experience is necessary in order to give an uncomplicated anaesthetic. A mathematical model which describes the pharmacokinetic behaviour of the drug was incorporated into a computerised delivery s... | ['Adult', 'Aged', 'Anesthesia, Intravenous', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Infusion Pumps', 'Infusions, Intravenous', 'Microcomputers', 'Middle Aged', 'Models, Biological', 'Propofol'] | 2,334,031 | [['M01.060.116'], ['M01.060.116.100'], ['E03.155.308'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.505', 'E07.858.082.505'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['L01.224.230.260.550'], ['M01.060.116.630'], ['E05.599.395'], ['D02.455.426.559.389.657.773']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
General practice vs surgical-based follow-up for patients with colon cancer: randomised controlled trial. | This trial examined the optimal setting for follow-up of patients after treatment for colon cancer by either general practitioners or surgeons. In all, 203 consenting patients who had undergone potentially curative treatment for colon cancer were randomised to follow-up by general practitioners or surgeons. Follow-up g... | ['Aged', 'Aged, 80 and over', 'Anxiety', 'Australia', 'Colonic Neoplasms', 'Continuity of Patient Care', 'Depression', 'Family Practice', 'Female', 'Follow-Up Studies', 'General Surgery', 'Humans', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Patient Satisfaction', 'Quality of Life', 'Recurren... | 16,622,437 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['Z01.639.100', 'Z01.678.100.373'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['F01.145.126.350'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Continuation of hormone replacement therapy in Slovenia: a prospective, randomized, controlled trial--1-year follow-up. | OBJECTIVES: To evaluate the influence of educational intervention on the hormone replacement therapy (HRT) continuation rate in Slovenia after the publication of WHI results.METHODS: We enrolled 125 early postmenopausal women in a 12-month prospective, randomized, controlled, multicentric study in Slovenia. The study g... | ['Adult', 'Estrogen Replacement Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Patient Compliance', 'Patient Education as Topic', 'Prospective Studies', 'Slovenia'] | 16,293,377 | [['M01.060.116'], ['E02.319.452.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['I02.233.332.500', 'N02.421.726.407.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Expression level of miRNA-663 in different leukemic cell lines and its biological function]. | The aim of the research was to find the up-regulated microRNA (miRNA) in K562 cells treated by 5-aza, to detect the miRNA expression in healthy people, CML patients and leukemia cell lines and to investigate the influence of miRNA on K562 cell proliferation. Up-regulated miRNA in K562 cells after 5-aza treatment was sc... | ['Cell Proliferation', 'CpG Islands', 'DNA Methylation', 'Gene Expression Regulation, Leukemic', 'Humans', 'K562 Cells', 'Leukemia', 'MicroRNAs', 'U937 Cells'] | 21,518,471 | [['G04.161.750', 'G07.345.249.410.750'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G05.308.370.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.510', 'A11.251.860.180.510', 'A11.443.240.497.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TLR-Induced IL-12 and CCL2 Production by Myeloid Cells Is Dependent on Adenosine A3 | TLR-induced signaling potently activates cells of the innate immune system and is subject to regulation at different levels. Inflammatory conditions are associated with increased levels of extracellular adenosine, which can modulate TLR-induced production of cytokines through adenosine receptor-mediated signaling. Ther... | ['Antigen-Presenting Cells', 'Chemokine CCL2', 'Humans', 'Interferon-gamma', 'Interleukin-12', 'Interleukin-17', 'Myeloid Cells', 'Receptor, Adenosine A3', 'Signal Transduction', 'THP-1 Cells', 'Toll-Like Receptors'] | 30,804,043 | [['A11.066', 'A15.382.066'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893',... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Statistical validation of the identification of tuna species: bootstrap analysis of mitochondrial DNA sequences. | Sequencing of the mitochondrial cytochrome b gene has been used to differentiate three tuna species: Thunnus albacares (yellowfin tuna), Thunnus obesus (bigeye tuna), and Katsuwonus pelamis (skipjack). A PCR amplified 528 bp fragment from 30 frozen samples and a 171 bp fragment from 26 canned samples of the three speci... | ['Animals', 'Base Sequence', 'DNA, Mitochondrial', 'Meat', 'Molecular Sequence Data', 'Phylogeny', 'Polymorphism, Genetic', 'Reproducibility of Results', 'Sequence Alignment', 'Sequence Homology, Amino Acid', 'Species Specificity', 'Tuna'] | 11,853,465 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.283.225'], ['G07.203.300.600', 'J02.500.600'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.365.795'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.393.751'], ['G02.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Clinical effect and metabolism of S-sulfonated immunoglobulin in 7 patients with congenital humoral immunodeficiency. | 7 patients with primary humoral immunodeficiency were given an S-sulfonated IgG preparation, 100 mg/kg i.v. at intervals of 3--4 weeks, for treatment of, or prophylaxis against, infection. The clinical effects and metabolism of S-sulfonated IgG were studied. No side reactions attributable to S-sulfonated IgG occurred ... | ['Animals', 'Bacterial Infections', 'Child', 'Child, Preschool', 'Guinea Pigs', 'Half-Life', 'Humans', 'Immunoglobulin G', 'Immunologic Deficiency Syndromes', 'Injections, Intravenous', 'Male', 'Passive Cutaneous Anaphylaxis', 'Sulfonic Acids'] | 573,934 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Positive airway pressure therapy in heart failure patients: Long-term effects on lung function. | PURPOSE: The prevalence of sleep-disordered breathing (SDB) in patients with heart failure (HF) is high. Positive airway pressure (PAP) is first-choice therapy, but recent data indicates that PAP therapy may increase mortality in HF patients with reduced ejection fraction (HF-REF) and predominant central sleep apnea (C... | ['Aged', 'Aged, 80 and over', 'Continuous Positive Airway Pressure', 'Female', 'Heart Failure', 'Humans', 'Longitudinal Studies', 'Lung', 'Male', 'Middle Aged', 'Polysomnography', 'Respiratory Function Tests', 'Respiratory System', 'Retrospective Studies', 'Stroke Volume', 'Vital Capacity'] | 28,126,479 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['A04.411'], ['M01.060.116.630'], ['E01.370.520.625'], ['E01.370.386... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Non-insulin-dependent diabetes mellitus with early onset in Blacks and Indians. | Non-insulin-dependent diabetes mellitus (NIDDM) with onset below 35 years of age was studies in 43 Indian and 9 Black patients. NIDDM was diagnosed in 10.0% and 1.6% of diabetes in the respective racial groups. The mean age of the patients was 35.4 years and the mean duration of diabetes 7.5 years. Nearly 50% of patien... | ['Adolescent', 'Adult', 'African Americans', 'African Continental Ancestry Group', 'Age Factors', 'Blood Glucose', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'India', 'Insulin', 'Male', 'Middle Aged'] | 7,020,102 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['N05.715.350.075', 'N06.850.490.250'], ['D09.947.875.359.448.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['D06.472.699.587.200.500.... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Concordance between self-reported and physician-reported chronic co-morbidity among disabled older adults. | Discordance between self-reports and medical records reflects patient and provider factors that have implications for management and research. This study investigated discordance and socio-demographic factors that explain concordance. A purposive sample of 402 disabled older persons was interviewed using a structured q... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Comorbidity', 'Disabled Persons', 'Educational Status', 'Ethnic Groups', 'Female', 'Humans', 'Male', 'Self Report', 'Surveys and Questionnaires'] | 23,915,947 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.225', 'N06.850.490.687'], ['M01.150'], ['N01.824.196'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.500', 'N05.715.360.300.800.500', 'N06.850.520.308.980.500'], ['E... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Supply usage data base helps set best practices. | As hospitals move more quickly toward managed care, the impact of industry changes is taking its toll. Networks and systems are rapidly being formed throughout the industry. One advantage of network formation is group purchasing and system-wide contract development. Bundling large volume contracts can produce lower pri... | ['Benchmarking', 'California', 'Cost Control', 'Database Management Systems', 'Equipment and Supplies, Hospital', 'Group Purchasing', 'Hospital Information Systems', 'Materials Management, Hospital', 'Organizational Case Studies'] | 10,176,840 | [['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N03.219.151.160'], ['L01.224.068', 'L01.224.900.280', 'N04.452.515.110'], ['E07.325'], ['N02.278.216.500.968.679.375', 'N03.219.463.430', 'N04.452.442.452.422.679.3... | ['Health Care [N]', 'Geographicals [Z]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Control of composition and activity of the photosynthetic apparatus of Rhodopseudomonas capsulata grown in ammonium-limited continuous culture. | Rhodopseudomonas capsulata was grown either phototropically in the light or chemotrophically in the dark at oxygen tensions of 5 mm and 3 mm Hg in ammonium-limited continuous culture. During growth limitation bacteriochlorophyll content of cells and membranes varied dependent on growth rate drastically in chemotrophic ... | ['Adenosine Triphosphate', 'Aerobiosis', 'Anaerobiosis', 'Bacterial Proteins', 'Bacteriochlorophylls', 'Oxidative Phosphorylation', 'Oxygen Consumption', 'Photophosphorylation', 'Photosynthesis', 'Quaternary Ammonium Compounds', 'Rhodopseudomonas'] | 1,217,939 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.017', 'G03.049'], ['G02.111.062', 'G03.078'], ['D12.776.097'], ['D03.383.129.578.840.374.100', 'D03.633.400.909.374.100', 'D04.345.783.374.100', 'D12.776.752.249'], ['G02.111.665.550', 'G03.295.631', 'G03.796.550'], ['G03.680'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chediak-Higashi syndrome with intestinal complication. Report of a case. | A 21-year-old woman with Chediak-Higashi syndrome developed intestinal lesions similar to those of Crohn's disease. Radiographic findings showed a stenotic lesion with multiple nodular changes in the ascending colon and cecum, and a longitudinal ulceration in the terminal ileum. In addition, multiple oval-shaped ulcera... | ['Adult', 'Chediak-Higashi Syndrome', 'Colon', 'Crohn Disease', 'Female', 'Humans', 'Intestinal Mucosa'] | 3,680,907 | [['M01.060.116'], ['C11.270.040.772', 'C15.378.553.774.257', 'C16.320.798.375', 'C20.673.774.257', 'C20.673.795.375'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gamma delta (ãä) T-cells are critical in the up-regulation of inducible nitric oxide synthase at the burn wound site. | BACKGROUND: The high incidence of morbidity and mortality following major burn can in part be attributed to immune derangements and wound healing complications. Inflammation plays an important role in wound healing, of which inducible nitric oxide synthase (iNOS) derived nitric oxide is a central mediator. T-cells of t... | ['Animals', 'Burns', 'Chemokines', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Nitric Oxide Synthase Type II', 'Receptors, Antigen, T-Cell, gamma-delta', 'Skin', 'Up-Regulation', 'Wound Healing'] | 22,831,879 | [['B01.050'], ['C26.200'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D08.811.682.664.500.772.500', 'D12.776.157.687.575', 'D12.776.660... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disposable electrochemical immunosensor diagnosis device based on nanoparticle probe and immunochromatographic strip. | We describe a disposable electrochemical immunosensor diagnosis device that integrates the immunochromatographic strip technique with an electrochemical immunoassay and exploits quantum dot (QD, CdS@ZnS) as labels for amplifying signal output. The device takes advantage of the speed and low cost of the conventional imm... | ['Antibodies', 'Chromatography', 'Electrochemistry', 'Humans', 'Immunoassay', 'Nanoparticles', 'Prostate-Specific Antigen', 'Quantum Dots'] | 17,877,418 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.196.181'], ['H01.181.529.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['J01.637.512.600'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866.249.500', 'D... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
CNN as model observer in a liver lesion detection task for x-ray computed tomography: A phantom study. | PURPOSE: The purpose of this study was the evaluation of anthropomorphic model observers trained with neural networks for the prediction of a human observer's performance.METHODS: To simulate liver lesions, a phantom with contrast targets (acrylic spheres, varying diameters, +30 HU) was repeatedly scanned on a computed... | ['Image Processing, Computer-Assisted', 'Liver Neoplasms', 'Neural Networks, Computer', 'Phantoms, Imaging', 'ROC Curve', 'Tomography, X-Ray Computed'] | 30,137,658 | [['L01.224.308'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['G17.485', 'L01.224.050.375.605'], ['E07.671'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.8... | ['Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Azolla pinnata growth performance in different water sources. | Azolla pinnata R.Br. growth performance experiments in different water sources were conducted from May until July 2011 at Aquaculture Research Station, Puchong, Malaysia. Four types of water sources (waste water, drain water, paddy field water and distilled water) each with different nutrient contents were used to grow... | ['Biomass', 'Nitrates', 'Phosphorus', 'Tracheophyta', 'Water'] | 24,218,931 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.268.666'], ['B01.650.940.800.575.912'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
6-Mercaptopurine-induced recurrent acute pancreatitis in children with acute lymphoblastic leukemia/lymphoma. | Two children with acute lymphoblastic leukemia/lymphoma developed recurrent acute pancreatitis during treatment; the etiology was presumed to be secondary to 6-mercaptopurine (6MP). Both had no further attacks after discontinuation of 6MP. Acute pancreatitis secondary to 6MP is extremely rare in acute leukemia/lymphoma... | ['Adolescent', 'Antimetabolites, Antineoplastic', 'Child', 'Humans', 'Male', 'Mercaptopurine', 'Pancreatitis', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma'] | 23,138,114 | [['M01.060.057'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.489.534', 'D03.633.100.759.570'], ['C06.689.750'], ['C04.557.337.428.600', 'C15.604.515.560.600', 'C20.683.515.528.600']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of climate and exurban development on nest predation and predator presence in the southern Appalachian Mountains (USA). | In the eastern United States, land-use and climate change have likely contributed to declines in the abundance of Neotropical migrant birds that occupy forest interiors, but the mechanisms are not well understood. We conducted a nest-predation experiment in southern Appalachian Mountain forests (North Carolina, U.S.A.)... | ['Animals', 'Birds', 'Food Chain', 'Human Activities', 'Humans', 'North Carolina', 'Population Density', 'Reproduction', 'Seasons', 'Temperature'] | 22,624,665 | [['B01.050'], ['B01.050.150.900.248'], ['G16.500.275.157.250', 'N06.230.124.250'], ['I03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['N01.224.600', 'N06.850.505.400.600'], ['G08.686.784'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.52... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
In vitro antimicrobial susceptibility, plasmid analysis, and serotyping of epidemic-associated Campylobacter jejuni. | Campylobacter jejuni strains from 11 outbreaks were characterized by antimicrobial susceptibility, plasmid profile, and serotyping by the methods of Lior et al. and Penner and Hennessy. All 31 strains were susceptible to erythromycin, clindamycin, chloramphenicol, kanamycin, tobramycin, streptomycin, and gentamicin. A ... | ['Animals', 'Anti-Bacterial Agents', 'Campylobacter Infections', 'Campylobacter fetus', 'Cattle', 'Diarrhea', 'Disease Outbreaks', 'Drug Resistance, Microbial', 'Female', 'Humans', 'Microbial Sensitivity Tests', 'Plasmids', 'Serotyping', 'United States'] | 3,968,203 | [['B01.050'], ['D27.505.954.122.085'], ['C01.150.252.400.177'], ['B03.440.180.325', 'B03.660.150.235.250.500.220'], ['B01.050.150.900.649.313.500.380.271'], ['C23.888.821.214'], ['N06.850.290'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Caregiver staffing in nursing homes and their influence on quality of care: using dynamic panel estimation methods. | BACKGROUND: There is inconclusive evidence that nursing home caregiver staffing characteristics influence quality of care. In this research, the relationship of caregiver staffing levels, turnover, agency use, and professional staff mix with quality is further examined using a longitudinal analysis to overcome weakness... | ['Health Care Surveys', 'Humans', 'Nursing Assistants', 'Nursing Homes', 'Nursing Staff', 'Outcome Assessment, Health Care', 'Personnel Staffing and Scheduling', 'Personnel Turnover', 'Population Dynamics', 'Quality Improvement', 'Quality Indicators, Health Care', 'United States', 'Workforce'] | 21,577,182 | [['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.067.652', 'N02.360.067.652'], ['N02.278.825.610'], ['M01.526.485.680', 'N02.360.680'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Curcuminoids distinctly exhibit antioxidant activities and regulate expression of scavenger receptors and heme oxygenase-1. | SCOPE: Curcumin (CUR), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC) have been demonstrated as having antioxidant, anticarcinogenic, and hypocholesterolemic activities. We report the diverse antiatherogenic effects and mechanisms of curcuminoids.METHODS AND RESULTS: We found that CUR was the most potent anti... | ['Antioxidants', 'Biomarkers', 'CD36 Antigens', 'Cell Differentiation', 'Cell Line, Tumor', 'Copper', 'Curcumin', 'Diarylheptanoids', 'Foam Cells', 'Gene Expression Regulation', 'Glutamate-Cysteine Ligase', 'Heme Oxygenase-1', 'Humans', 'Lipid Peroxidation', 'Lipoproteins, LDL', 'Monocytes', 'Scavenger Receptors, Class... | 23,386,263 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D23.101'], ['D12.776.157.530.300.500', 'D12.776.395.550.625.136', 'D12.776.543.550.625.136', 'D12.776.543.585.300.500', 'D12.776.543.750.011', 'D12.776.543.750.705.675.136', 'D12.776.543.750.705.940.625.249', 'D12.776.543.750.710.450.750.625.249'], ['G04... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction. | BACKGROUND: Cruciferous vegetables are a major dietary source of isothiocyanates that may protect against coronary heart disease. Isothiocyanates induce glutathione S-transferases (GSTs), polymorphic genes that code for enzymes that conjugate isothiocyanates, as well as mutagens and reactive oxygen species, to make the... | ['Brassica', 'Case-Control Studies', 'Diet', 'Female', 'Gene Frequency', 'Genotype', 'Glutathione Transferase', 'Humans', 'Isothiocyanates', 'Logistic Models', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Nutrigenomics', 'Odds Ratio', 'Polymorphism, Genetic', 'Risk Factors', 'Smoking', 'Vegetables'] | 17,823,442 | [['B01.650.940.800.575.912.250.157.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.203.650.240'], ['G05.330'], ['G05.380'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.500.375', 'D02.886.250'], ['E05.318.740.500.525', 'E05.318.740.600.800.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Use of immunoblotting as an alternative method for serogrouping Leptospira. | Leptospirosis is a worldwide zoonotic disease caused by a spirochaete bacterium, Leptospira. Serological detection of this micro-organism basically relies on a conventional microscopic agglutination test (MAT), which has some limitations and disadvantages. In the present study, immunoblotting has been applied as an alt... | ['Antibodies, Bacterial', 'Antigens, Bacterial', 'Burkholderia pseudomallei', 'Epitopes', 'Escherichia coli', 'Helicobacter pylori', 'Immunoblotting', 'Leptospira', 'Molecular Weight', 'Serotyping'] | 17,446,278 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['B03.660.075.090.688.100.600'], ['D23.050.550'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['E05.478.566.320', 'E05.601.470.320'], ['B03.440... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Personality variables as predictors of early non-metastatic colorectal cancer patients' psychological distress and health-related quality of life: a one-year prospective study. | OBJECTIVE: We aimed to assess the course of early non-metastatic colorectal cancer patients' psychological distress and health-related quality of life (HRQOL) and to identify relevant clinical and psychological predictors during a one-year period.METHODS: Of the 144 early non-metastatic colorectal cancer patients initi... | ['Aged', 'Analysis of Variance', 'Anxiety', 'Colorectal Neoplasms', 'Defense Mechanisms', 'Depression', 'Female', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Personality', 'Personality Assessment', 'Predictive Value of Tests', 'Prospective Studies', 'Quality of Life', 'Stress, Psychological', 'Surveys and Questi... | 21,511,071 | [['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.470.132'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['F01.393'], ['F01.145.126.350'], ['I01.240.425', 'N01.224.425', 'N06.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Haplophytin-A and B: the alkaloidal constituents of Haplophyllum acutifolium. | During the phytochemical investigation of Haplophyllum acutifolium, two alkaloids named haplophytin-A (1) and B (2) have been obtained. In addition, some known constituents: flindersine (3), kusunokinin (4), beta-sitosterol, oleanolic acid, cholesterol and hexadecanoic acid, have also been obtained. The known constitue... | ['Alkaloids', 'Cholesterol', 'Magnetic Resonance Spectroscopy', 'Oleanolic Acid', 'Pakistan', 'Palmitic Acid', 'Plants', 'Sitosterols', 'Spectrophotometry, Infrared'] | 11,454,359 | [['D03.132'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.196.867.519'], ['D02.455.849.919.530.733', 'D02.455.849.919.650.600'], ['Z01.252.245.723'], ['D10.251.694.750'], ['B01.650'], ['D04.210.500.247.222.857', 'D04.210.500.247.808.756.669', 'D10.570.938.795.669', 'D23.704.500.669'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Control of bacteriophage mu lysogenic repression. | The transposable and temperate phage Mu infects Escherichia coli where it can enter the lytic life-cycle or reside as a repressed and integrated prophage. The repressor protein Rep is the key element in the lysis-lysogeny decision. We have analyzed the fate of Rep in different mutants by Western blotting under two cond... | ['Bacteriophage mu', 'Chromatin Immunoprecipitation', 'Gene Expression Regulation, Viral', 'Lysogeny', 'Models, Genetic', 'Mutation', 'Repressor Proteins', 'Temperature', 'Viral Proteins'] | 16,154,589 | [['B04.123.150.500.260', 'B04.123.205.260', 'B04.280.090.500.260'], ['E05.393.170', 'E05.478.605.160'], ['G05.308.385'], ['G05.935.500', 'G06.920.877.500'], ['E05.599.395.397'], ['G05.365.590'], ['D12.776.260.703', 'D12.776.930.780'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of different types of diffusive gradient in thin film samplers for measurement of dissolved methylmercury in freshwaters. | Determination of bioavailable concentrations of methylmercury (MeHg(+)) in freshwater is key to further understanding its potential risk and toxicity. In this work, two in-house-manufactured mercury-specific diffusive gradients in thin films (DGT) were used in laboratory to assess the lability of MeHg(+), and to develo... | ['Acrylic Resins', 'Calibration', 'Chromatography, Gas', 'Diffusion', 'Environmental Monitoring', 'Fresh Water', 'Materials Testing', 'Mercury', 'Organic Chemicals', 'Quality Control', 'Sepharose', 'Solid Phase Extraction', 'Spectrometry, Fluorescence', 'Temperature', 'Thiourea', 'Water Pollutants, Chemical'] | 25,127,623 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['E05.978.155'], ['E05.196.181.349'], ['G01.202', 'G02.196'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.280', 'N06.230.232'], ['E05.570'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D02'], ['J01.897.608'], ... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Fulvimonas soli gen. nov., sp. nov., a gamma-proteobacterium isolated from soil after enrichment on acetylated starch plastic. | Six deep-yellow-pigmented strains were isolated from soil after enrichment on plasticized acetylated starch granules as a source of carbon. They showed very similar and unique fatty acid profiles, consisting almost exclusively of branched fatty acids. The strains consisted of small, motile rods, were oxidase- and catal... | ['Acetylation', 'Bacterial Typing Techniques', 'Biodegradation, Environmental', 'Culture Media', 'DNA, Ribosomal', 'Fatty Acids', 'Gammaproteobacteria', 'Molecular Sequence Data', 'Phenotype', 'Phylogeny', 'Plastics', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Soil Microbiology', 'Starch'] | 12,148,641 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.475'], ['D10.251'], ['B03.660.250'], ['L01.453.245.667'], ['G05.695'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D0... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Chemical characterization and biological activities of Simmondsia chinensis (Link) C. K. Schneid seeds oil. | The chemical composition, main physicochemical properties, and biological activities of Simmondsia chinensis (S. chinensis) seeds oil were studied. The results revealed that the physiochemical characteristics of S. chinensis seeds oil were as follows: acid values 1.15 mg KOH/g, peroxide values 8.00 meq O2 Kg-1, iodine ... | ['Acetylcholinesterase', 'Anti-Bacterial Agents', 'Antioxidants', 'Bacillus cereus', 'Bacillus subtilis', 'Biphenyl Compounds', 'Caryophyllales', 'Cholinesterase Inhibitors', 'Enterococcus faecalis', 'Fatty Acids', 'Liquid-Liquid Extraction', 'Listeria monocytogenes', 'Microbial Sensitivity Tests', 'Phenols', 'Picrates... | 29,631,679 | [['D08.811.277.352.100.170.176'], ['D27.505.954.122.085'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218.252'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Role of Sp1 and Sp3 in the nutrient-regulated expression of the human asparagine synthetase gene. | The human asparagine synthetase (AS) gene responds to depletion of mammalian cells for either amino acids or carbohydrates. Five specific cis-elements have been implicated: three GC boxes (GC-I, GC-II and GC-III) and two nutrient-sensing response elements (NSRE-1, -2). This study shows that all three GC boxes are requi... | ['Animals', 'Aspartate-Ammonia Ligase', 'Base Sequence', 'Blotting, Northern', 'Carbohydrate Metabolism', 'Cell Line', 'Cell Nucleus', 'DNA', 'DNA-Binding Proteins', 'Drosophila', 'Humans', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Promoter Regions, Genetic', 'Protein Binding', 'RNA', 'Sp1 Transcription... | 11,867,623 | [['B01.050'], ['D08.811.464.259.200.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G02.111.158', 'G03.191'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D13.444.308'], ['D12.776.260'], ['B01.050.500.131.617.720.500.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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