Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library. | Gramicidin A (1) is a peptide antibiotic that disrupts the transmembrane ion concentration gradient by forming an ion channel in a lipid bilayer. Although long used clinically, it is limited to topical application because of its strong hemolytic activity and mammalian cytotoxicity, likely arising from the common ion tr... | ['Animals', 'Anti-Bacterial Agents', 'Cell Line, Tumor', 'Chemistry, Pharmaceutical', 'Drug Discovery', 'Erythrocytes', 'Feasibility Studies', 'Gram-Positive Bacteria', 'Gramicidin', 'Hemolysis', 'High-Throughput Screening Assays', 'Inhibitory Concentration 50', 'Mice', 'Microbial Sensitivity Tests', 'Molecular Structu... | 33,004,797 | [['B01.050'], ['D27.505.954.122.085'], ['A11.251.210.190', 'A11.251.860.180'], ['H01.158.703.007', 'H01.181.466'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B03.510'], ['D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Endoscopic endonasal double flap technique for reconstruction of large anterior skull base defects: technical note. | INTRODUCTION: One of the main concerns in endoscopic endonasal approaches to the skull base has been the high incidence and morbidity associated with cerebrospinal fluid leaks. The introduction and routine use of vascularized flaps allowed a marked decrease in this complication followed by a great expansion in the indi... | ['Adult', 'Cadaver', 'Cerebrospinal Fluid Rhinorrhea', 'Endoscopy', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Meningeal Neoplasms', 'Meningioma', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Nasal Cavity', 'Postoperative Complications', 'Reconstructive Surgical Procedures', 'Skull Base Neo... | 29,754,975 | [['M01.060.116'], ['C23.550.260.224'], ['C10.597.114.750', 'C10.900.300.109.750', 'C23.888.592.114.624', 'C23.888.852.834.500', 'C26.915.300.225.750'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.557.580.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of cell cycle genes and induction of senescence by overexpression of OTX2 in medulloblastoma cell lines. | The transcription factor orthodenticle homeobox 2 (OTX2) has been implicated in the pathogenesis of medulloblastoma, as it is often highly expressed and sometimes amplified in these tumors. Little is known of the downstream pathways regulated by OTX2. We therefore generated MED8A and DAOY medulloblastoma cell lines wit... | ['Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Cellular Senescence', 'Cerebellar Neoplasms', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Medulloblastoma', 'Otx Transcription Factors'] | 21,047,732 | [['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.043'], ['C04.588.614.250.195.411.211', 'C10.228.140.211.500.200', 'C10.228.140.252.200', 'C10.551.240.250.400.300'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.600.380.515', 'C04.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of equitoxic radioimmunotherapy and chemotherapy in the treatment of human colonic cancer xenografts. | The therapeutic efficacy of 5-fluorouracil (5-FUra; 0.6 mg/day x 5 days) + leucovorin (LV; 1.8 mg/day x 5 days) and of 131I-labeled MN-14 anticarcinoembryonic antigen IgG (275 microCi single dose) was evaluated in size-matched (0.3-0.7 cm3) s.c. LoVo, HT-29, DLD-1, HCT-15, LS174T, and MOSER, GW-39, and WidR human colon... | ['Animals', 'Cell Division', 'Colonic Neoplasms', 'Combined Modality Therapy', 'Drug Administration Schedule', 'Female', 'Fluorouracil', 'Humans', 'Leucovorin', 'Mice', 'Mice, Nude', 'Radioimmunotherapy', 'Transplantation, Heterologous', 'Tumor Cells, Cultured'] | 8,261,435 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E02.186'], ['E02.319.283'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.40... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brainstem auditory evoked responses in term small for gestational age newborn infants born to undernourished mothers. | Our aim was to assess the effect of intrauterine growth retardation on neurosensory development by evaluating brainstem auditory evoked responses (BAER) in term small for gestational age (SGA) newborn infants born to undernourished mothers. This prospective clinical study included 25 singleton healthy SGA newborn infan... | ['Brain Stem', 'Case-Control Studies', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Fetal Growth Retardation', 'Humans', 'Infant, Newborn', 'Infant, Small for Gestational Age', 'Male', 'Mothers', 'Nutrition Disorders', 'Pregnancy', 'Pregnancy Complications', 'Prospective Studies', 'Reaction Time'] | 12,697,429 | [['A08.186.211.132'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.4... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Generalized Shwartzman reaction caused by group A beta-hemolytic Streptococcus, resulting in maternal death. A case report. | Group A beta-hemolytic Streptococcus is a rare cause of peripartum infection, but it remains an extremely virulent pathogen with devastating consequences, thus requiring awareness of its presentation. We describe a case of fulminant group A Streptococcus sepsis resulting in a generalized Shwartzman reaction and death i... | ['Adult', 'Disseminated Intravascular Coagulation', 'Fatal Outcome', 'Female', 'Humans', 'Puerperal Disorders', 'Sepsis', 'Shwartzman Phenomenon', 'Streptococcal Infections', 'Streptococcus pyogenes', 'Time Factors'] | 7,966,050 | [['M01.060.116'], ['C15.378.100.220', 'C15.378.463.250', 'C15.378.925.220'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.844'], ['C01.757', 'C23.550.470.790.500'], ['C14.907.454.810', 'C14.90... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Predicted coronary heart disease risk reduction and dual blood pressure/cholesterol goal attainment in patients with hypertension treated in real-world clinical practice. | Hypertension and dyslipidemia are highly co-prevalent, but often poorly controlled, coronary heart disease (CHD) risk factors. A retrospective cohort study was conducted between January 2004 and April 2008 to compare estimated 10-year CHD risk reduction and dual blood pressure and low-density lipoprotein cholesterol go... | ['Amlodipine', 'Anticholesteremic Agents', 'Antihypertensive Agents', 'Atorvastatin', 'Blood Pressure', 'Calcium Channel Blockers', 'Cholesterol, LDL', 'Cohort Studies', 'Coronary Artery Disease', 'Databases, Factual', 'Drug Therapy, Combination', 'Female', 'Health Records, Personal', 'Heptanoic Acids', 'Humans', 'Hype... | 20,591,084 | [['D03.383.725.203.065'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D27.505.954.411.162'], ['D03.383.129.578.075', 'D10.251.450.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease. | The relationship between regulatory T cells (Tregs) and acute graft-versus-host disease (aGVHD) in clinical allogeneic bone marrow transplantation (BMT) recipients is not well established. We conducted a prospective analysis of peripheral blood Tregs as determined by the frequency of CD4(+)CD25(hi)FOXP3(+) lymphocytes ... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Forkhead Transcription Factors', 'Graft vs Host Disease', 'Humans', 'Infant', 'Interleukin-2 Receptor alpha Subunit', 'Male', 'Middle Aged', 'Phenotype', 'Prognosis', 'Prospective Studies', 'T-Lymphocyte Subsets', 'T-Lymphocytes, R... | 20,302,964 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['C20.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D12.776.543.750.705.852.420.320.500'], ['M01.060.116.630'], ['G05.695'], ['E... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Elongation of actin filaments is a diffusion-limited reaction at the barbed end and is accelerated by inert macromolecules. | We used a fluorescence method to measure the rate constants for the elongation of pyrene-labeled actin filaments in a number of different solvents. The absolute values of the rate constants were established by electron microscopy. Using glycerol, sucrose, or ethylene glycol to vary the solution viscosity, the associati... | ['Actins', 'Animals', 'Diffusion', 'Ethylene Glycol', 'Ethylene Glycols', 'Glycerol', 'Mathematics', 'Microscopy, Electron', 'Polymers', 'Rabbits', 'Spectrometry, Fluorescence', 'Sucrose', 'Temperature', 'Viscosity'] | 3,745,211 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['G01.202', 'G02.196'], ['D02.033.455.250.268'], ['D02.033.455.250'], ['D02.033.800.875.500', 'D09.853.875.500'], ['H01.548'], ['E01.370.350.515.402', 'E05.595.402'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['B01.050.150.900.649.313... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Aspergillosis mycetoma of the maxillary antrum. | Aspergillus is a fungus, usually found growing as one of the many moulds of fruit, foods and nuts. This paper deals with a ball of fungus growing in the maxillary antrum of an elderly female patient presenting as a radio-opaque expansile mass. In man, aspergillus fumigatus and aspergillus flavis have both been incrimin... | ['Aged', 'Aspergillosis', 'Female', 'Humans', 'Maxillary Sinus', 'Paranasal Sinus Diseases'] | 6,961,938 | [['M01.060.116.100'], ['C01.150.703.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.531.621.578'], ['C08.460.692', 'C09.603.692']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression of Id-1 mRNA and protein in the post-ischemic regenerating rat kidney. | The basic helix-loop-helix (bHLH) class of proteins are of major importance in controlling tissue-specific gene expression. The actions of the bHLH proteins are inhibited by a related class of proteins, inhibitors of differentiation (Id). We have studied the expression of one of these latter proteins, Id-1, in the norm... | ['Animals', 'Blotting, Western', 'Gene Expression', 'Helix-Loop-Helix Motifs', 'Inhibitor of Differentiation Protein 1', 'Ischemia', 'Kidney', 'Male', 'Proliferating Cell Nuclear Antigen', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Regeneration', 'Repressor Proteins', 'Transcription Factors', 'Vimentin'] | 9,639,041 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G05.297'], ['G02.111.570.820.709.275.500.360'], ['D12.776.930.329.249'], ['C23.550.513'], ['A05.810.453'], ['D12.776.660.740', 'D23.050.290.750', 'D23.101.140.600'], ['D13.444.735.544'], ['B01.050.150.90... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of cholinergic overstimulation on isoflurane potency and efficacy in cortical and spinal networks. | In scenarios of terrorist attacks with organophosphorus compounds it appears likely that medical aid is required by victims not only suffering from the intoxication but also from physical trauma. These subjects may have to undergo surgical interventions, raising the need for anaesthesia. This prompts the question of ho... | ['Acetylcholine', 'Action Potentials', 'Anesthetics, Inhalation', 'Animals', 'Female', 'In Vitro Techniques', 'Isoflurane', 'Mice', 'Mice, Inbred Strains', 'Neocortex', 'Neurons', 'Organophosphate Poisoning', 'Pregnancy', 'Spinal Cord'] | 17,141,935 | [['D02.092.211.111'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['B01.050'], ['E05.481'], ['D02.355.601.570'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['A08.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dynamic expression pattern of Hoxc8 during mouse early embryogenesis. | The Hoxc8 expression pattern was examined in mouse embryos 7.5-12.5 days postcoitum (dpc) using whole-mount in situ hybridization and RT-PCR. The expression of Hoxc8 started between 7.5 and 8.5 dpc. A strong expression was detected in the ectoderm and mesoderm at 8.5 dpc. At 9.5 dpc, a distinct anterior boundary of Hox... | ['Animals', 'Cell Differentiation', 'Embryonic Development', 'Gene Expression Regulation, Developmental', 'Gestational Age', 'Homeodomain Proteins', 'In Situ Hybridization', 'Mice', 'Mice, Inbred ICR', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction'] | 15,674,821 | [['B01.050'], ['G04.152'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['G05.308.310'], ['G07.345.500.325.235.968', 'G08.686.320'], ['D12.776.260.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['B01.050.150.900.649.313.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real-time selected ion flow tube mass spectrometry to assess short- and long-term variability in oral and nasal breath. | Breath-based non-invasive diagnostics have the potential to provide valuable information about a person's health status. However, they are not yet widely used in clinical practice due to multiple factors causing variability and the lack of standardized procedures. This study focuses on the comparison of oral and nasal ... | ['Adult', 'Breath Tests', 'Computer Systems', 'Exhalation', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Ions', 'Male', 'Mass Spectrometry', 'Middle Aged', 'Mouth', 'Nose', 'Reproducibility of Results', 'Time Factors', 'Volatile Organic Compounds', 'Young Adult'] | 32,422,613 | [['M01.060.116'], ['E01.370.100'], ['L01.224.230'], ['G09.772.705.700.275'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497'], ['E05.196.566'], ['M01.060.116.630'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['A01.456.505.733', 'A04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Role of Pseudomonas aeruginosa in the etiology of infectious complications in cancer patients]. | The occurrence of Pseudomonas aeruginosa in various pathologic materials and feces from patients with different cancer was compared. The rate of Pseudomonas aeruginosa-associated postoperative complications versus the frequency of intraoperative detection of the organism was studied. The sensitivity of Pseudomonas aeru... | ['Anti-Bacterial Agents', 'Cross Infection', 'Gastrointestinal Neoplasms', 'Humans', 'Neoplasms', 'Postoperative Complications', 'Pseudomonas Infections', 'Pseudomonas aeruginosa'] | 3,099,468 | [['D27.505.954.122.085'], ['C01.248', 'C23.550.291.875.500'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['C23.550.767'], ['C01.150.252.400.739'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancing informed consent best practices: gaining patient, family and provider perspectives using reverse simulation. | BACKGROUND: Obtaining informed consent in the clinical setting is an important yet challenging aspect of providing safe and collaborative care to patients. While the medical profession has defined best practices for obtaining informed consent, it is unclear whether these standards meet the expressed needs of patients, ... | ['Attitude of Health Personnel', 'Communication', 'Family', 'Health Personnel', 'Humans', 'Informed Consent', 'Memory', 'Models, Theoretical', 'Patient Education as Topic', 'Patient Satisfaction', 'Patients', "Practice Patterns, Physicians'", 'Videotape Recording'] | 22,522,147 | [['F01.100.050', 'N05.300.100'], ['F01.145.209', 'L01.143'], ['F01.829.263', 'I01.880.853.150'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['F02.463.425.540'], ['E05.599'], ['I02.233.332.500'... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
Successful prophylaxis for fungal peritonitis in patients on continuous ambulatory peritoneal dialysis: six years' experience. | Fungal peritonitis as a serious complication of continuous ambulatory peritoneal dialysis (CAPD) is often associated with severe morbidity, CAPD "drop-out" and, occasionally, death. Most episodes of fungal peritonitis occur during or after a period of antibiotic treatment of various bacterial infections, usually bacter... | ['Administration, Oral', 'Anti-Bacterial Agents', 'Bacterial Infections', 'Candidiasis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nystatin', 'Peritoneal Dialysis, Continuous Ambulatory', 'Peritonitis'] | 1,986,569 | [['E02.319.267.100'], ['D27.505.954.122.085'], ['C01.150.252'], ['C01.150.703.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.540.505.575'], ['E02.760.106.500', 'E02.870.300.650.500', 'E02.912.800.650.500', 'N02.421.585.106.500'], ['C01.463.600', 'C06.844.640']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Applications of ultrasound in the treatment of the complications of breast augmentation with polyacrylamide hydrogel injection]. | OBJECTIVE: To search for a simple and non-invasive method to assist the treatment of the complications of breast augmentation with polyacrylamide hydrogel injection.METHODS: High-frequency ultrasound was used to examine the breast and observe the distributions of the injected polyacrylamide hydrogel. The operation proc... | ['Acrylic Resins', 'Adult', 'Breast', 'Female', 'Humans', 'Injections', 'Surgery, Plastic', 'Treatment Outcome', 'Ultrasonography, Mammary'] | 15,179,869 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['M01.060.116'], ['A01.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['H02.403.810.788'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['E01.370.350.850.860', 'E01.370.378.850']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Genetic analysis of echovirus 11 variability in adsorption to human erythrocytes. | The frequency of nonhemagglutinating (h-) mutants was determined in hemagglutinating (HA) clones of echovirus 11. The HA clones were derived from the prototype strain Gregory and a clinical isolate of echovirus 11. The h- mutants were found at a constant frequency of 3.0 x 10(-5) (mean value) in the HA clones derived f... | ['Animals', 'Cell Adhesion', 'Cells, Cultured', 'Chlorocebus aethiops', 'Culture Techniques', 'Enterovirus B, Human', 'Erythrocytes', 'Hemagglutination', 'Humans', 'Mutation', 'Point Mutation', 'Rats'] | 8,279,949 | [['B01.050'], ['G04.022'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.481.500'], ['B04.820.578.750.284.182'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G02.111.026.500', 'G12.122.100.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['G05.365.590.675'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The experience of being 30-45 years of age and depending on haemodialysis treatment: a phenomenological study. | The aim of this study was to describe how haemodialysis (HD) patients, between 30 and 45 years of age, experience their dependence on HD treatment. Nine patients undergoing HD treatment were interviewed. The transcribed texts were analysed according to Giorgi's four basic principles. Being between 30 and 45 years of ag... | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nursing Care', 'Renal Dialysis'] | 20,409,058 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.611', 'N02.421.533'], ['E02.870.300', 'E02.912.800']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of lining materials on the composite resins shrinkage stresses. | Recently, three types of lining materials have been used in dental clinics, conventional powder-liquid glass ionomer cement, light-cured powder-liquid glass ionomer cement and a light-cured single paste type. This study compared the effects of these lining materials on the shrinkage stress of light-cured composite resi... | ['Acrylic Resins', 'Composite Resins', 'Dental Cavity Lining', 'Dental Cements', 'Glass Ionomer Cements', 'Hydroxyapatites', 'Materials Testing', 'Resin Cements', 'Silicon Dioxide', 'Time Factors'] | 7,842,636 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.323.225'], ['D25.339.291', 'J01.637.051.339.291'], ['D25.339.291.402', 'J01.637.051.339.291.402'], ['D01.029.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Working with groups in patient education. | Group processes are an effective means of helping individuals change their behavior. Of six types of group events, three have particular relevance in the health-care setting: individually oriented change groups, group-process oriented change groups, and focused-criterion groups. The role health professionals can play i... | ['Group Processes', 'Humans', 'Patient Education as Topic', 'Self-Help Groups', 'United States'] | 10,268,814 | [['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.233.332.500', 'N02.421.726.407.680'], ['N03.540.782'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
A longitudinal study of HPV detection and cervical pathology in HIV infected women. | OBJECTIVE: To monitor the presence and persistence of high risk (HR) human papillomavirus (HPV) in cervical brushings from HIV infected women.METHODS: Prospective observational cohort study of HIV infected women. Women were enrolled from the cohort of 164 HIV infected women who attend the colposcopy clinic at the Edinb... | ['Adult', 'Cervical Intraepithelial Neoplasia', 'Cohort Studies', 'Female', 'HIV Infections', 'Humans', 'Longitudinal Studies', 'Middle Aged', 'Papillomaviridae', 'Papillomavirus Infections', 'Prevalence', 'Prospective Studies', 'Scotland', 'Uterine Cervical Diseases', 'Uterine Cervical Neoplasms'] | 11,026,879 | [['M01.060.116'], ['C04.557.470.200.240.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The impact of health-care reform on the cancer patient. | Reform of the United States' health-care system as we know it will require a reevaluation of the methods used in health-care delivery. Many changes are emerging in the health-care marketplace, and there is a prevailing trend toward universal coverage through managed care/competition. Global cost-control measures will b... | ['Antitrust Laws', 'Economic Competition', 'Health Care Reform', 'Humans', 'Managed Care Programs', 'Neoplasms', 'Taxes', 'United States'] | 8,402,518 | [['N03.706.615.100'], ['N03.219.188'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['C04'], ['N03.219.900'], ['Z01.107.567.875']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Tension-free vaginal tape exposure presenting as a recurrent sterile paraurethral abscess. | We report a case of tension-free vaginal tape (TVT) exposure presenting as a recurrent sterile paraurethral abscess at 25 months and 40 months following successful continence surgery and describe the management of this problem. | ['Abscess', 'Cystoscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Postoperative Complications', 'Prosthesis Implantation', 'Recurrence', 'Surgical Mesh', 'Ultrasonography', 'Urethral Diseases', 'Urinary Incontinence, Stress', 'Vagina'] | 15,846,455 | [['C01.830.025', 'C23.550.470.756.100'], ['E01.370.388.250.180', 'E01.370.390.175', 'E04.502.250.180', 'E04.950.774.155'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E04.650'], ['C23.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The sensitizing effect of a Brucella abortus antigen in cattle after repeated intradermal inoculations. | An antigen prepared from a mucoid strain of B. abortus was repeatedly injected intradermally into cattle to determine whether it sensitizes cattle so that they test false positive with the skin delayed-type hypersensitivity (SDTH) test. Cattle (n = 14) that were experimentally inoculated. with microorganisms that serol... | ['Animals', 'Antibodies, Bacterial', 'Antigens, Bacterial', 'Brucella abortus', 'Brucellosis, Bovine', 'Cattle', 'False Positive Reactions', 'Hypersensitivity, Delayed', 'Injections, Intradermal', 'Skin Tests'] | 8,828,125 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['B03.440.400.425.215.500.100', 'B03.660.050.070.100.100'], ['C01.150.252.400.167.322', 'C22.021.322', 'C22.196.148'], ['B01.050.150.900.649.313.500.380.271'], ['E01.354.506'], ['C20.543.418'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improving midterm results justify the continued use of bare-metal stents for endovascular therapy for chronic mesenteric ischemia. | OBJECTIVE: The objective of this study was to evaluate the contemporary results of interventions in the celiac axis (CA) and superior mesenteric artery (SMA) for chronic mesenteric ischemia (CMI) and factors associated with patency and symptom-free survival.METHODS: A retrospective review of patients with CMI treated w... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Celiac Artery', 'Chronic Disease', 'Endovascular Procedures', 'Female', 'Humans', 'Male', 'Mesenteric Artery, Superior', 'Mesenteric Ischemia', 'Mesenteric Vascular Occlusion', 'Metals', 'Middle Aged', 'Ohio', 'Progression-Free Survival', 'Retrospective Studies', 'Risk Asse... | 31,327,617 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.114.207'], ['C23.550.291.500'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.565.755'], ['C06.405.469.656', 'C06.844.460', 'C14.907.549'], ['C06.405.469.675', 'C06.844.5... | ['Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes. | We present evidence that the microtubule-associated protein tau is present in oligodendrocytes (OLGs), the central nervous system cells that make myelin. By showing that tau is distributed in a pattern similar to that of myelin basic protein, our results suggest a possible involvement of tau in some aspect of myelinati... | ['Animals', 'Blotting, Western', 'Brain', 'Cells, Cultured', 'Electrophoresis, Polyacrylamide Gel', 'Fluorescent Antibody Technique, Indirect', 'Immunohistochemistry', 'In Situ Hybridization, Fluorescence', 'Microscopy, Immunoelectron', 'Myelin Basic Protein', 'Oligodendroglia', 'Rats', 'Sheep', 'tau Proteins'] | 7,479,786 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['A11.251'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Potential unrecognised costs of clopidogrel pretreatment in acute coronary syndrome. | OBJECTIVE: To examine adherence in clinical practice to the American College of Cardiology/American Heart Association (ACC/AHA) guideline recommendations of observing a 5-day waiting period after clopidogrel administration before undergoing coronary artery bypass graft (CABG) surgery and to examine the costs of waiting... | ['Acute Coronary Syndrome', 'Aged', 'American Heart Association', 'Blood Transfusion', 'Clopidogrel', 'Coronary Artery Bypass', 'Costs and Cost Analysis', 'Female', 'Guideline Adherence', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Platelet Aggregation Inhibitors', 'Postoperative Complications', 'Practice Guide... | 19,824,808 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116.100'], ['N03.540.630.780.110'], ['E02.095.135'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['N03.219.151'], ['N04.761.337', 'N... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of the Performance of Skin Prick, ImmunoCAP, and ISAC Tests in the Diagnosis of Patients with Allergy. | BACKGROUND: Allergy is diagnosed from typical symptoms, and tests are performed to incriminate the suspected precipitant. Skin prick tests (SPTs) are commonly performed, inexpensive, and give immediate results. Laboratory tests (ImmunoCAP) for serum allergen-specific IgE antibodies are usually performed more selectivel... | ['Female', 'Food Hypersensitivity', 'Humans', 'Immunologic Tests', 'Male', 'Sensitivity and Specificity'] | 28,456,812 | [['C20.543.480.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812', 'E05.200.812', 'E05.478.594'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Tumor Necrosis Factor-producing T-regulatory Cells Are Associated With Severe Liver Injury in Patients With Acute Hepatitis A. | BACKGROUND AND AIMS: CD4+CD25+Foxp3+ T-regulatory (Treg) cells control immune responses and maintain immune homeostasis. However, under inflammatory conditions, Treg cells produce cytokines that promote inflammation. We investigated production of tumor necrosis factor (TNF) by Treg cells in patients with acute hepatiti... | ['Acute Disease', 'Antigens, CD', 'Apyrase', 'Case-Control Studies', 'Cells, Cultured', 'DNA Methylation', 'Epigenesis, Genetic', 'Forkhead Transcription Factors', 'Hepatitis A', 'Hepatitis A virus', 'Host-Pathogen Interactions', 'Humans', 'Interleukin-2 Receptor alpha Subunit', 'Liver', 'Nuclear Receptor Subfamily 1, ... | 29,229,400 | [['C23.550.291.125'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D08.811.277.040.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.251'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G05.308.203'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Wasting your assets--how to make better use of the NHS estate. | The impact of the health reforms together with other developments will mean that the 24 billion pounds NHS estate will undergo the most fundamental change since the days of Florence Nightingale. Against this background it is more important than ever that the utilisation of the estate is improved and that the NHS learns... | ['Efficiency, Organizational', 'Hospital Design and Construction', 'Maintenance and Engineering, Hospital', 'State Medicine', 'United Kingdom'] | 10,134,705 | [['N04.452.209.500'], ['J01.086.339.250', 'N02.278.200.403'], ['N02.278.216.500.968.450', 'N02.628.472', 'N04.452.442.452.422.450'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Clozapine treatment in patients with prior substance abuse. | OBJECTIVE: This study examined outcomes following discharge on clozapine for treatment-resistant schizophrenia patients with and without diagnosed substance abuse histories.METHODS: Those discharged on clozapine from a research unit between April 1991 and March 1996 were followed with respect to hospitalization status.... | ['Adult', 'Antipsychotic Agents', 'Brief Psychiatric Rating Scale', 'Clozapine', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Humans', 'Male', 'Prevalence', 'Schizophrenia', 'Substance-Related Disorders', 'Time Factors'] | 12,655,909 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F04.711.513.653.083'], ['D03.633.300.240.220'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The relationship between prevalence of active trachoma, water availability and its use in a Tanzanian village. | This study aimed to establish the relationship between the prevalence of active trachoma in children, water availability and household water use in a village in Tanzania. Nine hundred and fourteen children aged 1-9 years were examined for signs of trachoma. Data were collected on time taken to collect water, amount of ... | ['Child', 'Child, Preschool', 'Female', 'Humans', 'Hygiene', 'Infant', 'Male', 'Multivariate Analysis', 'Prevalence', 'Risk Factors', 'Rural Health', 'Socioeconomic Factors', 'Tanzania', 'Trachoma', 'Water Supply'] | 16,546,229 | [['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.547', 'N06.850.670'], ['M01.060.703'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.7... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming. | The NLRP3 inflammasome is activated in response to microbial and danger signals, resulting in caspase-1-dependent secretion of the proinflammatory cytokines IL-1â and IL-18. Canonical NLRP3 inflammasome activation is a two-step process requiring both priming and activation signals. During inflammasome activation, NLRP3... | ['Animals', 'Cardiolipins', 'Caspase 1', 'Inflammasomes', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mitochondria', 'NLR Family, Pyrin Domain-Containing 3 Protein'] | 29,602,772 | [['B01.050'], ['D10.570.755.375.760.400.885.185', 'D23.050.550.480.330'], ['D08.811.277.656.262.500.126.550.100', 'D08.811.277.656.300.200.126.550.100', 'D12.644.360.075.405.550.100', 'D12.776.476.075.405.550.100'], ['D05.500.224'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of prior exercise on hamstring flexibility: a comparison of proprioceptive neuromuscular facilitation and static stretching. | Position stands from the American College of Sports Medicine and the Surgeon General site a need for strategies capable of enhancing the effectiveness of stretching on flexibility and joint range of motion. One strategy for enhancing flexibility that has received anecdotal support but lacks substantial experimental evi... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Female', 'Humans', 'Leg', 'Male', 'Muscle Contraction', 'Muscle, Skeletal', 'Neuromuscular Junction', 'Pliability', 'Proprioception', 'Range of Motion, Articular'] | 12,930,174 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['A08.800.550.550.550', 'A08.850.550.550', 'A11.284.149.165.420.780.550.550'], ['G01.374.705'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social adjustment profiles of female drivers involved in fatal and nonfatal accidents. | Previous research by the authors has shown that male drivers involved in fatal and nonfatal accidents can be differentiated from the general population on the basis of background, behavior, and social adjustment. The results of the present study suggest that female drivers involved in serious crashes do not differ from... | ['Accidents, Traffic', 'Age Factors', 'Ethanol', 'Humans', 'Marriage', 'Mortality', 'Seat Belts', 'Social Adjustment', 'Social Control, Formal', 'Women'] | 869,059 | [['N06.850.135.392'], ['N05.715.350.075', 'N06.850.490.250'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N01.824.308.500.500'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Direct antiviral therapy for treatment of hepatitis C: A real-world study from Brazil. | INTRODUCTION AND OBJECTIVES: Direct antiviral agents (DAAs) including sofosbuvir (SOF), daclatasvir (DCV), simeprevir (SIM) and ombitasvir, paritaprevir and dasabuvir were introduced 2015 in Brazil for treatment of hepatitis C virus (HCV) infection. The aims of this study were to assess effectiveness and safety of HCV ... | ['Aged', 'Antiviral Agents', 'Brazil', 'Drug Therapy, Combination', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Imidazoles', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Prognosis', 'Prospective Studies', 'Ribavirin', 'Sex Factors', 'Simeprevir', 'Sofosbuvir', 'Sustained Virologic Response'] | 31,537,509 | [['M01.060.116.100'], ['D27.505.954.122.388'], ['Z01.107.757.176'], ['E02.319.310'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.38... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Does Surgical Repair Still have a Role for Iatrogenic Tracheobronchial Rupture? Clinical Analysis of a Thoracic Surgeon's Opinion. | PURPOSE: The choice of surgical repair or conservative treatment for iatrogenic tracheobronchial rupture (ITBR) remains controversial. However, thoracic surgeons consider that surgical repair is an important treatment modality. The purpose of this study was to evaluate the clinical results from the perspective of the s... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bronchi', 'Child', 'Female', 'Humans', 'Iatrogenic Disease', 'Intubation, Intratracheal', 'Length of Stay', 'Lung Injury', 'Male', 'Middle Aged', 'Patient Selection', 'Respiration, Artificial', 'Retrospective Studies', 'Risk Factors', 'Rupture', 'Suture Techniques',... | 27,840,372 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A04.411.125'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.875'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E02.760.400.480', 'N02.421.585.400.480'], ['C08.381.520', 'C26.891.554'], ['M01.060.11... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Vaccination-induced variation in the 140 kD merozoite surface antigen of Plasmodium knowlesi malaria. | Immunity to 143/140 kD schizont antigens of a monkey malaria, Plasmodium knowlesi, provides partial protection to lethal malaria infection in rhesus monkeys challenged with uncloned parasites. To determine the capacity of a cloned parasite to generate variants of the 143/140 kD antigens, immunized monkeys were challeng... | ['Animals', 'Antigens, Protozoan', 'Antigens, Surface', 'Erythrocytes', 'Genetic Variation', 'Immunosorbent Techniques', 'Macaca mulatta', 'Malaria', 'Plasmodium', 'Vaccination'] | 3,546,574 | [['B01.050'], ['D23.050.293'], ['D23.050.301'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G05.365'], ['E05.478.566.380', 'E05.601.470.380'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['C01.610.752.530', 'C01.920.875'], ['B01.043.075.380.611'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Acute ischemic transection of peripheral axons in angiopathic neuropathy. No demyelination of fasciculus gracilis or decreased number or size of cytons of spinal ganglion neurons. | Demyelination (loss of myelin profiles) of posterior columns of the spinal cord in patients with neuropathy coming to autopsy usually has been interpreted as secondary to distal degeneration of peripheral nerve fibers. Previous experiments to test whether these pathologic changes could result from transecting periphera... | ['Acute Disease', 'Cell Count', 'Female', 'Ganglia, Spinal', 'Humans', 'Ischemia', 'Male', 'Middle Aged', 'Nerve Fibers, Myelinated', 'Peripheral Nerves', 'Spinal Cord'] | 1,237,824 | [['C23.550.291.125'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513'], ['M01.060.116.630'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.514'], ['A08.800.800'], ['... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Completion arteriography in paramalleolar bypasses: effect of configurational changes, with special reference to spasm, on long-term outcome. | PURPOSE: The purpose of this study was to ascertain the durability of paramalleolar bypasses and elucidate the effect of configurational changes, especially spasm, seen on the completion arteriography upon the outcome.DESIGN: Retrospective study.SETTING: University hospital experience.PATIENTS AND METHODS: Nineteen par... | ['Adult', 'Aged', 'Aged, 80 and over', 'Amputation Stumps', 'Angiography', 'Ankle', 'Arterial Occlusive Diseases', 'Arteriosclerosis', 'Blood Vessel Prosthesis', 'Female', 'Graft Occlusion, Vascular', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Retrospective Studies', 'Saphenous Vein', 'Spasm', 'Surgical Flaps', 'Thromboa... | 8,971,579 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A01.378.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A01.378.610.050'], ['C14.907.137'], ['C14.907.137.126'], ['E07.695.110'], ['C23.550.767.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['E05.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Echocardiographic aspects of supravalvular aortic stenosis (author's transl)]. | Seven patients with hemodynamic and angiocardiographic diagnosis of supravalvular aortic stenosis were studied by single plane echocardiography. 3 patients had the hypoplastic and 3 the "hourglass" type of the disease. 3 patients underwent surgical repair of the malformation, with postoperative echocardiographic contro... | ['Adolescent', 'Adult', 'Angiography', 'Aorta', 'Aortic Valve Stenosis', 'Child', 'Echocardiography', 'Female', 'Heart Defects, Congenital', 'Hemodynamics', 'Humans', 'Male'] | 852,654 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A07.015.114.056'], ['C14.280.484.048.750', 'C14.280.955.249'], ['M01.060.406'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['G09.330.380'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple sites of the cleavage of 17- and 19-mer encephalytogenic oligopeptides corresponding to human myelin basic protein (MBP) by specific anti-MBP antibodies from patients with systemic lupus erythematosus. | In contrast to canonical proteases, myelin basic protein (MBP)-Sepharose-purified IgG from multiple sclerosis (MS) and systemic lupus erythematosus (SLE) patients efficiently hydrolyze only MBP, but not many other tested proteins. It was shown that anti-MBP SLE IgGs cleave nonspecific tri- and tetrapeptides with an ext... | ['Amino Acid Sequence', 'Antibodies, Catalytic', 'Humans', 'Immunoglobulin G', 'Kinetics', 'Lupus Erythematosus, Systemic', 'Molecular Sequence Data', 'Molecular Weight', 'Multiple Sclerosis', 'Myelin Basic Protein', 'Peptide Fragments', 'Proteolysis', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 22,781,164 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.167', 'D12.776.124.790.651.114.167', 'D12.776.377.715.548.114.167'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['G01.374.661', 'G02.111... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Interview with the Hon. Ken Wyatt: improving Indigenous health outcomes from a political viewpoint. | In 2017, Australia celebrates 50 years since the 1967 referendum, when more than 90% of Australians voted to amend the constitution to allow the national government to create laws for Indigenous people and include them in the census. We spoke with the Honourable Ken Wyatt, the Minister for Indigenous Health and the Min... | ['Australia', 'Health Policy', 'Health Services, Indigenous', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Oceanic Ancestry Group', 'Politics', 'Quality of Health Care'] | 29,114,711 | [['Z01.639.100', 'Z01.678.100.373'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N02.421.330'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.600'], ['I01.738'], ['N04.761', 'N05.715']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Quantitative analysis of hyaluronan in human synovial fluid using capillary electrophoresis. | The glycosaminoglycan, hyaluronan, can be detected in human synovial fluid by capillary electrophoresis (CE). Variations in peak shape make this technique unsuitable for quantitative analysis of hyaluronan in raw synovial fluid. Quantitative analysis was achieved by hydrolysis of the polymeric hyaluronan to the tetrasa... | ['Arthritis, Rheumatoid', 'Carbohydrate Sequence', 'Electrophoresis, Capillary', 'Glycosaminoglycans', 'Humans', 'Hyaluronic Acid', 'Knee Joint', 'Molecular Sequence Data', 'Osteoarthritis', 'Synovial Fluid', 'Time Factors'] | 8,900,949 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G02.111.570.160', 'L01.453.245.667.160'], ['E05.196.401.190', 'E05.301.300.190'], ['D09.698.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['A02.835.583.475'], ['L01.453.245.667'], ['C05.550.114.606', 'C05.799.613'], ... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Epileptic negative myoclonus: a combined study of EEG and [123I]iomazenil (123I-IMZ) single photon emission computed tomography indicating involvement of medial frontal area. | Negative myoclonus (NM) is a sudden brief atonia in muscle that causes jerky lapses of posture. This study employed an electrophysiological technique (silent-period-locked-averaging (SPLA) electroencephalography (EEG)) and a pharmacodynamic imaging technique (123I-IMZ-SPECT) to examine epileptic NM (ENM). Delayed-phase... | ['Electroencephalography', 'Epilepsies, Myoclonic', 'Flumazenil', 'Frontal Lobe', 'Humans', 'Iodine Radioisotopes', 'Male', 'Reaction Time', 'Receptors, GABA-A', 'Tomography, Emission-Computed, Single-Photon', 'Young Adult'] | 20,133,106 | [['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375.130', 'C10.228.140.490.493.063'], ['D03.633.100.079.080.070.305'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['E05.796.817', 'F02.830.650', 'F04.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Chromosomal translocation involving USP6 gene in nodular fasciitis]. | OBJECTIVE: To investigate the frequency of USP6 gene rearrangement in nodular fasciitis (NF) and to evaluate its clinical application.METHODS: Twenty nine cases of previously diagnosed NF were screened for the presence of the USP6 gene rearrangement by interphase fluorescence-in-situ hybridization (FISH) on formalin-fi... | ['Fasciitis', 'Gene Rearrangement', 'Humans', 'In Situ Hybridization, Fluorescence', 'Interphase', 'Proto-Oncogene Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Translocation, Genetic', 'Ubiquitin Thiolesterase'] | 25,346,123 | [['C05.321'], ['G05.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['G04.144.500'], ['D12.776.624.664.700'], ['E05.393.620.500.725'], [... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Motor neuron disease and multiple sclerosis mortality in Australia, New Zealand and South Africa compared with England and Wales. | There has been a marked increase in the reported mortality from motor neuron disease (MND) but not multiple sclerosis (MS) in England and Wales and in a number of other countries. A comparison has been made of the mortality from MND and from MS for two time periods in Australia, New Zealand and South Africa. An increas... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Australia', 'England', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motor Neuron Disease', 'Multiple Sclerosis', 'New Zealand', 'Sex Factors', 'South Africa', 'Wales'] | 8,509,776 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.574.562', 'C10.668.467'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.5... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Panic disorder in the medically ill. | The authors describe five patients with concurrent panic disorder and medical illness. Panic disorder either caused worsening of the medical illness or was associated with continued physiologic symptoms that mimicked the symptoms of the medical illness after the illness had improved. In both cases, panic disorder was a... | ['Adult', 'Anxiety Disorders', 'Attitude to Health', 'Disease', 'Fear', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neurocognitive Disorders', 'Panic', 'Stress, Psychological'] | 2,760,001 | [['M01.060.116'], ['F03.080'], ['F01.100.150', 'N05.300.150'], ['C23.550.288'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.615'], ['F01.470.361.585'], ['F01.145.126.990', 'F02.830.900']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of chemotherapeutic agents and cytokines on the expression of 5-fluorouracil-associated enzymes in human colon cancer cell lines. | BACKGROUND: Several studies have demonstrated that intratumoral expression of catabolizing and anabolizing enzymes for 5-fluorouracil (5-FU) is important in the response of cancers to 5-FU-based chemotherapy. We investigated the influence of other chemotherapeutic agents or cytokines, which are often administered for e... | ['Antimetabolites, Antineoplastic', 'Apoptosis', 'Caco-2 Cells', 'Camptothecin', 'Cell Line, Tumor', 'Cisplatin', 'Colonic Neoplasms', 'Cytokines', 'Dihydrouracil Dehydrogenase (NADP)', 'Fluorouracil', 'HT29 Cells', 'Humans', 'Interferons', 'Ligands', 'Mitomycin', 'Orotate Phosphoribosyltransferase', 'Paclitaxel', 'RNA... | 16,568,373 | [['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['G04.146.954.035'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['D03.132.151'], ['A11.251.210.190', 'A11.251.860.180'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Application of EMF emission measurement techniques to wireless communications systems for compliance with directive 2004/40/EC. | Europe is the only region in the world with common legislative acts regulating exposure to electromagnetic fields (EMF) for both the general public and workers. Council Recommendation 1999/519/EC deals with the limitation of exposure of the general public to EMF (0 Hz-300 GHz). Directive 2004/40/EC regulates the minimu... | ['Computer Communication Networks', 'Electromagnetic Fields', 'Europe', 'European Union', 'Guideline Adherence', 'Guidelines as Topic', 'Humans', 'Occupational Exposure', 'Radiation Monitoring', 'Telecommunications'] | 16,790,175 | [['L01.224.230.110'], ['G01.358.500.260', 'G01.358.750.500'], ['Z01.542'], ['I01.615.500.475'], ['N04.761.337', 'N05.715.360.395'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['L01.178.847']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Review of recommendations for reforms to the coroner's office. | The Inquiry that was set up following the conviction of Dr Shipman for the murder of 15 of his patients produced three reports, the third of which considered the present system for death and cremation certification and the investigation of deaths by coroners (Shipman Inquiry, 2003b). The report makes extensive recommen... | ['Autopsy', 'Cause of Death', 'Coroners and Medical Examiners', 'Death Certificates', 'Forensic Medicine', 'Health Care Reform', 'Health Planning Guidelines', 'Homicide', 'Humans', 'Malpractice', 'Medical Errors', "Nurse's Role", 'Professional Role', 'State Medicine', 'United Kingdom'] | 15,580,077 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.526.485.230', 'N02.360.230'], ['E05.318.308.940.350', 'L01.399.250.900.350', 'N04.452.859.264', 'N05.715.360.300.715.315', 'N06.850.520.308.940.350'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Surgical salvage of bleeding peptic ulcers after failed therapeutic endoscopy. | BACKGROUND: The approach to salvage surgery after failed endoscopic therapy for a bleeding peptic ulcer is controversial. We aimed to compare the outcomes of salvage surgery after failed endoscopic therapy for bleeding peptic ulcers over a 10-year period.METHODS: Patients receiving salvage surgery for bleeding peptic u... | ['Aged', 'China', 'Cohort Studies', 'Endoscopy, Digestive System', 'Female', 'Humans', 'Male', 'Medical Audit', 'Middle Aged', 'Peptic Ulcer Hemorrhage', 'Postoperative Complications', 'Retrospective Studies', 'Salvage Therapy', 'Treatment Outcome'] | 19,556,796 | [['M01.060.116.100'], ['Z01.252.474.164'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.372.250', 'E01.370.388.250.250', 'E04.210.240', 'E04.502.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05.700.175.500'], ['M01.060.116.630'], ['C06.... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cross-talk among noradrenaline, adenosine and protein kinase C in the mechanisms of ischemic preconditioning in rabbits. | To date, there are two pathways discussed as a mechanism of ischemic preconditioning. Activation of protein kinase C by ischemic preconditioning increases adenosine release. The increased adenosine further activates protein kinase C through adenosine A1 receptors, and activated protein kinase C induces an infarct size-... | ['Adenosine', 'Animals', 'Blood Pressure', 'Heart Rate', 'Ischemic Preconditioning, Myocardial', 'Male', 'Norepinephrine', 'Protein Kinase C', 'Rabbits', 'Signal Transduction'] | 12,688,395 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E02.592.325', 'E05.516.325'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Carbamazepine in the treatment of depressive syndromes]. | Carbamazepine treatment was used with 54 patients suffering from endogenous depression and organic depression. The anti-depressive effect was found to be the best in those patients with organic depression, while in endogenous depression it was better with bipolar affective disorder and with irregular EEG recordings. | ['Adolescent', 'Adult', 'Aged', 'Carbamazepine', 'Depressive Disorder', 'Female', 'Hospitalization', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Middle Aged'] | 1,301,605 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D03.633.300.240.127'], ['F03.600.300'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
From bench to humans: formulation development of a poorly water soluble drug to mitigate food effect. | This study presents a formulation approach that was shown to mitigate the dramatic food effect observed for a BCS Class II drug. In vitro (dissolution), in vivo (dog), and in silico (GastroPlus®) models were developed to understand the food effect and design strategies to mitigate it. The results showed that such model... | ['Animals', 'Chemistry, Pharmaceutical', 'Dogs', 'Food-Drug Interactions', 'Humans', 'Solubility'] | 24,442,773 | [['B01.050'], ['H01.158.703.007', 'H01.181.466'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.968.511'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.805']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Bee venom acupuncture for rheumatoid arthritis: a systematic review protocol. | INTRODUCTION: This systematic review aims to analyse the trial data on the effects of bee venom acupuncture (BVA) for rheumatoid arthritis (RA).METHODS AND ANALYSIS: The following 14 databases will be searched from their inception to March 2014: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL),... | ['Acupuncture Therapy', 'Arthritis, Rheumatoid', 'Bee Venoms', 'Humans', 'Systematic Reviews as Topic'] | 24,760,349 | [['E02.190.044'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D20.888.065.115', 'D23.946.833.065.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682.759.575']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Age-related decrease in the N-methyl-D-aspartateR-mediated excitatory postsynaptic potential in hippocampal region CA1. | Glutamatergic fast synaptic transmission is known to be altered with age in a region-specific manner in hippocampus of memory-impaired old rats. In the present experiment, presynaptic fiber potentials and non-N-methyl-D-aspartate (NMDAR) and NMDAR-mediated synaptic responses in CA1 were compared in three ages of behavi... | ['Aging', 'Animals', 'Behavior, Animal', 'Hippocampus', 'Long-Term Potentiation', 'Male', 'Memory', 'N-Methylaspartate', 'Rats', 'Rats, Inbred F344', 'Receptors, Glutamate', 'Spatial Behavior', 'Synaptic Transmission'] | 9,330,977 | [['G07.345.124'], ['B01.050'], ['F01.145.113'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G11.561.638.350'], ['F02.463.425.540'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.200', 'B01.050.150.900.649.313.992.635.505.700.400.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tethered cord syndrome in children with anorectal malformations. | OBJECT: Anorectal malformations are known to be associated with neurological deficits, which may contribute to the disability suffered by patients with these malformations. This study was undertaken to determine the incidence and pattern of sacral abnormalities in children with anorectal malformations, the incidence an... | ['Anal Canal', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Lipoma', 'Male', 'Meningomyelocele', 'Neural Tube Defects', 'Neurologic Examination', 'Notochord', 'Radiography', 'Rectum', 'Sacrum', 'Spinal Cord', 'Spinal Cord Neoplasms', 'Spine', 'Syndrome... | 10,761,651 | [['A03.556.124.526.070', 'A03.556.249.249.070'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.52... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The relationship between bone mineral density and ultrasound in postmenopausal and osteoporotic women. | The aim of this cross-sectional study was to use a novel method of data analysis to demonstrate that patients with osteoporosis have significantly lower ultrasound results in the heel after correcting for the effect of bone mineral density (BMD) measured in the spine or hip. Three groups of patients were studied: healt... | ['Absorptiometry, Photon', 'Aged', 'Bone Density', 'Cross-Sectional Studies', 'Female', 'Femur Neck', 'Heel', 'Humans', 'Lumbar Vertebrae', 'Middle Aged', 'Osteoporosis, Postmenopausal', 'Reproducibility of Results', 'Ultrasonography'] | 9,666,937 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116.100'], ['G11.427.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A02.835.232.043.150.510'], ['A01.378.610.250.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cationic polythiophene-surfactant self-assembly complexes: phase transitions, optical response, and sensing. | The absorption and photoluminescence spectra of the cationic conjugated polyelectrolyte poly[3-(6-trimethylammoniumhexyl)thiophene] (P3TMAHT) were observed to be dramatically altered in the presence of anionic surfactants due to self-assembly through ionic complex formation. Small-angle neutron scattering (SANS), UV/vi... | ['Alkanesulfonic Acids', 'Fluorocarbons', 'Models, Molecular', 'Molecular Conformation', 'Optical Phenomena', 'Phase Transition', 'Polymers', 'Quaternary Ammonium Compounds', 'Surface-Active Agents', 'Thiophenes'] | 22,839,776 | [['D02.455.326.146.100', 'D02.886.645.600.055'], ['D02.455.526.510.435'], ['E05.599.595'], ['G02.111.570.820'], ['G01.590'], ['G01.645', 'G02.734'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D01.625.062.500', 'D02.092.877', 'D02.675.276'], ['D27.720.877'], ['D02.886.778', 'D03.383.903']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The use of osmolality as an aid to establishing consistent fixation quality: studies on the kidney of the domestic fowl. | 1. Using the proximal convoluted tubule of the fowl kidney as indicator tissue the immersion application of fixatives of differing composition and osmolality was studied. 2. The best results were obtained with Dalton's buffered osmium tetroxide and with sodium cacodylate buffered glutaraldehyde followed by osmium post-... | ['Animals', 'Chickens', 'Fixatives', 'Glutaral', 'Kidney Tubules', 'Osmium', 'Osmolar Concentration'] | 414,827 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D27.720.355'], ['D02.047.532'], ['A05.810.453.736.560'], ['D01.268.556.660', 'D01.268.956.702', 'D01.552.544.660'], ['G02.640']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cholecystokinin regulates satiation independently of the abdominal vagal nerve in a pig model of total subdiaphragmatic vagotomy. | The vagal nerve and gut hormones CCK and GLP-1 play important roles in the control of food intake. However, it is not clear to what extent CCK and GLP-1 increase satiation by stimulating receptors located on abdominal vagal nerve endings or via receptors located elsewhere. This study aimed to further explore the relati... | ['Acetaminophen', 'Animals', 'Blood Glucose', 'Cholecystokinin', 'Devazepide', 'Eating', 'Glucagon-Like Peptide 1', 'Glucagon-Like Peptide-1 Receptor', 'Hormone Antagonists', 'Insulin', 'Male', 'Models, Animal', 'Peptide Fragments', 'Postprandial Period', 'Receptors, Glucagon', 'Satiation', 'Sus scrofa', 'Vagotomy', 'V... | 25,449,395 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['B01.050'], ['D09.947.875.359.448.500'], ['D06.472.317.152', 'D12.644.120'], ['D03.633.100.079.080.070.200'], ['G07.203.650.283', 'G10.261.330'], ['D06.472.317.680.500.500'], ['D12.776.543.750.695.021.500', 'D12.776.543.750.750.360.100.500'], ['D06.347', 'D27.505.69... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contribution of extracellular signal-regulated kinase to angiotensin II-induced transforming growth factor-beta1 expression in vascular smooth muscle cells. | We have previously demonstrated that angiotensin II (Ang II) contributes to the increase in aortic transforming growth factor-beta(1) (TGF-beta(1)) mRNA levels in hypertensive rats. However, the molecular mechanism whereby Ang II promotes TGF-beta(1) expression in vascular smooth muscle cells (VSMCs) is poorly understo... | ['Angiotensin II', 'Angiotensin Receptor Antagonists', 'Animals', 'Aorta', 'Calcium-Calmodulin-Dependent Protein Kinases', 'DNA-Binding Proteins', 'Enzyme Activation', 'Enzyme Inhibitors', 'Flavonoids', 'Hypertension', 'Male', 'Muscle, Smooth, Vascular', 'Oligonucleotides, Antisense', 'Phosphorylation', 'Proto-Oncogene... | 10,406,835 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D27.505.519.162'], ['B01.050'], ['A07.015.114.056'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['D12.776.260'], ['G02.111.263', 'G03.328'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein. | We first determined whether oxidized high-density lipoprotein (ox-HDL) activates transcription factor nuclear factor-kappa B (NF-kappa B) in cultured human umbilical vein endothelial cells (HUVECs). Treatment for 7h with 100 microg/ml ox-HDL elicited a marked downregulation of I kappa B alpha and upregulation of the ph... | ['Blotting, Western', 'Cell Nucleus', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Endothelium', 'Endothelium, Vascular', 'Humans', 'Lipoproteins, HDL', 'Lipoproteins, LDL', 'NF-kappa B', 'Oxygen', 'Protein Binding', 'Reactive Oxygen Species', 'Time Factors'] | 12,646,204 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['A10.272.491'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intrinsic and extrinsic motivations for healthful dietary change in African Americans. | OBJECTIVE: To describe associations of intrinsic and extrinsic motivations for dietary change with participant characteristics and current diet among African Americans.METHODS: Cross-sectional survey of 658 African American adults in North Carolina provided information on intrinsic (self-image and health concerns) and ... | ['Adult', 'African Americans', 'Aged', 'Dietary Fats', 'Feeding Behavior', 'Female', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Surveys and Questionnaires'] | 17,691,877 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['E05.31... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Infants use meter to categorize rhythms and melodies: implications for musical structure learning. | Little is known about whether infants perceive meter, the underlying temporal structure of music. We employed a habituation paradigm to examine whether 7-month-old infants could categorize rhythmic and melodic patterns on the basis of the underlying meter, which was implied from event and accent frequency of occurrence... | ['Analysis of Variance', 'Association Learning', 'Child Development', 'Cues', 'Discrimination, Psychological', 'Female', 'Humans', 'Infant', 'Learning', 'Male', 'Music', 'Pattern Recognition, Physiological', 'Pitch Discrimination'] | 15,893,524 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.463.425.069.296'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.425.234'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F02.463.425', 'F02.784.629.529'], ['K01.602'], ['F02.463.593.524'], ['F02.463.593... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sensitivity and specificity of fine needle aspiration for the diagnosis of mediastinal lesions. | Fine needle aspiration cytology (FNAC) of mediastinal masses allows for rapid on-site evaluation and the triaging of material for ancillary studies. However, surgical pathology is often considered to be the gold standard for diagnosis. This study examines the sensitivity and specificity of FNAC compared to a concurrent... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biopsy, Fine-Needle', 'Child', 'Female', 'Humans', 'Male', 'Mediastinal Neoplasms', 'Middle Aged', 'Sensitivity and Specificity', 'Thoracic Surgical Procedures', 'Triage', 'Young Adult'] | 30,797,131 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['M01.060.406'], ['B0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication. | A complex containing the 80,000-dalton precursor to the adenovirus (Ad)-encoded terminal protein (pTP) and a 140,000-dalton protein is required for Ad DNA replication in vitro. This complex has been separated into subunits by glycerol gradient centrifugation in the presence of urea. The isolated 140,000-dalton subunit ... | ['Adenoviruses, Human', 'DNA Replication', 'DNA, Viral', 'DNA-Directed DNA Polymerase', 'HeLa Cells', 'Kinetics', 'Macromolecular Substances', 'Protein Precursors', 'Viral Proteins', 'Virus Replication'] | 6,957,861 | [['B04.280.030.500.350'], ['G02.111.225', 'G05.226'], ['D13.444.308.568'], ['D08.811.913.696.445.308.300'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G01.374.661', 'G02.111.490'], ['D05'], ['D12.776.811'], ['D12.776.964'], ['G06.920.925']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioral and neuronal investigations of hypervigilance in patients with fibromyalgia syndrome. | Painful stimuli are of utmost behavioral relevance and thereby affect attentional resources. In health, variable effects of pain on attention have been observed, indicating alerting as well as distracting effects of pain. In the human brain, these effects are closely related to modulations of neuronal gamma oscillation... | ['Adult', 'Aged', 'Anxiety', 'Attention', 'Electroencephalography', 'Female', 'Fibromyalgia', 'Humans', 'Male', 'Middle Aged', 'Neurons', 'Pain', 'Photic Stimulation', 'Surveys and Questionnaires'] | 22,509,383 | [['M01.060.116'], ['M01.060.116.100'], ['F01.470.132'], ['F02.830.104.214'], ['E01.370.376.300', 'E01.370.405.245'], ['C05.651.324', 'C05.799.321', 'C10.668.491.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.675', 'A11.671'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The serotonin receptor subtype 2 locus HTR2 is on human chromosome 13 near genes for esterase D and retinoblastoma-1 and on mouse chromosome 14. | Serotonin (5-hydroxytryptamine) functions as a neurotransmitter and a hormone. Its diverse actions are mediated by at least seven distinct cell surface receptor subtypes. The serotonin receptor subtype 2 (gene symbol HTR2) is a G-protein-coupled receptor, expressed primarily in the cerebral cortex, where upon stimulati... | ['Animals', 'Carboxylesterase', 'Carboxylic Ester Hydrolases', 'Chromosome Mapping', 'Chromosomes, Human, Pair 13', 'Genetic Linkage', 'Humans', 'Mice', 'Polymorphism, Restriction Fragment Length', 'Receptors, Serotonin', 'Retinoblastoma'] | 1,980,030 | [['B01.050'], ['D08.811.277.352.100.100'], ['D08.811.277.352.100'], ['E05.393.183'], ['A11.284.187.520.300.370.375', 'G05.360.162.520.300.370.375'], ['G05.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.795.595'], ['D12.776.543.750.670.800', 'D12.776.543.75... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Breastfeeding duration is a risk factor for atopic eczema. | BACKGROUND: The results of numerous studies on the influence of breastfeeding in the prevention of atopic disorders are often contradictory. One of the most important problems is confounding by other lifestyle factors.OBJECTIVE: The aim of the present study was to analyse the effect of any breastfeeding duration on the... | ['Age Distribution', 'Breast Feeding', 'Child', 'Child, Preschool', 'Cohort Studies', 'Dermatitis, Atopic', 'Female', 'Genetic Predisposition to Disease', 'Germany', 'Humans', 'Infant', 'Infant, Newborn', 'Prevalence', 'Risk Factors', 'Time Factors'] | 11,929,483 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193',... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A mouse model of â-thalassemia shows a liver-specific down-regulation of Abcc6 expression. | â-Thalassemia and pseudoxanthoma elasticum (PXE) are distinct genetic disorders. Yet, a dystrophic mineralization phenotype similar to PXE has frequently been associated with â-thalassemia or sickle cell anemia patients of Mediterranean descent. These calcifications are clinically and structurally identical to inherite... | ['ATP-Binding Cassette Transporters', 'Animals', 'Blotting, Western', 'Calcinosis', 'Disease Models, Animal', 'Down-Regulation', 'Fluorescent Antibody Technique', 'Kidney', 'Liver', 'Mice', 'Multidrug Resistance-Associated Proteins', 'Organ Specificity', 'Phenotype', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Tran... | 21,281,810 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C18.452.174.130'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G02.111.240', 'G05.308.200', 'G07.690.773... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Initial study to assess the effects of topical glyceryl trinitrate for pain after haemorrhoidectomy. | BACKGROUND: Postoperative pain remains the most dreaded part of haemorrhoidectomy in the minds of both patients and doctors. It may delay patient discharge, recovery, and return to work. Glyceryl trinitrate has been used successfully in the treatment of anal fissures. We investigated its topical use in the management o... | ['Administration, Topical', 'Aged', 'Double-Blind Method', 'Drug Administration Schedule', 'Female', 'Follow-Up Studies', 'Hemorrhoids', 'Humans', 'Male', 'Middle Aged', 'Nitroglycerin', 'Ointments', 'Pain Measurement', 'Pain, Postoperative', 'Postoperative Period', 'Probability', 'Reference Values', 'Statistics, Nonpa... | 12,678,539 | [['E02.319.267.120'], ['M01.060.116.100'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C06.405.469.860.401', 'C14.907.449'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantitative assessment and clinical relevance of VEGFRs-positive tumor cells in refractory brain tumors. | Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR)1 and 2 signaling is a potent activator of tumor angiogenesis. Although the expressions of VEGFR1 and VEGFR2 were initially thought to be limited to the endothelial cells, it is now known that both the receptors are expressed in tumor cells. This is the fir... | ['Adult', 'Aged', 'Brain Neoplasms', 'Chordoma', 'Endothelial Cells', 'Ependymoma', 'Female', 'Gene Expression Regulation, Neoplastic', 'Glioblastoma', 'Hemangioblastoma', 'Humans', 'Immunohistochemistry', 'Male', 'Meningioma', 'Middle Aged', 'Neovascularization, Pathologic', 'Neurilemmoma', 'Signal Transduction', 'Vas... | 32,088,190 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.557.465.220'], ['A11.436.275'], ['C04.557.465.625.600.380.290', 'C04.557.470.670.380.290', 'C04.557.580.625.600.380.290'], ['G05.308.370'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Mangrovicella endophytica gen. nov., sp. nov., a new member of the family Aurantimonadaceae isolated from Aegiceras corniculatum. | A Gram-negative, aerobic, motile and short-rod-shaped bacterium, designated strain 5T4P-12-1T, was isolated from a piece of surface-sterilized bark of Aegiceras corniculatum collected from Cotai Ecological Zones in Macao, China and tested by a polyphasic approach to clarify its taxonomic position. Strain 5T4P-12-1T gre... | ['Alphaproteobacteria', 'Bacterial Typing Techniques', 'Base Composition', 'China', 'DNA, Bacterial', 'Fatty Acids', 'Phospholipids', 'Phylogeny', 'Plant Bark', 'Primulaceae', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Ubiquinone'] | 30,010,526 | [['B03.660.050'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['Z01.252.474.164'], ['D13.444.308.212'], ['D10.251'], ['D10.570.755'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['A18.024.750.200'], ['B01.650.940.800.575.912.250.341.984'], ['D13.444.735.686.670'], ['E05.393.760.700'], ['D02.806.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Application of Gafchromic EBT2 film for intraoperative radiation therapy quality assurance. | PURPOSE: Intraoperative radiation therapy (IORT) using electron beam is commonly done by mobile dedicated linacs that have a variable range of electron energies. This paper focuses on the evaluation of the EBT2 film response in the green and red colour channels for IORT quality assurance (QA).METHODS: The calibration o... | ['Calibration', 'Electrons', 'Film Dosimetry', 'Humans', 'Intraoperative Period', 'Monte Carlo Method', 'Quality Control', 'Radiotherapy Dosage', 'Radiotherapy, Computer-Assisted'] | 25,703,011 | [['E05.978.155'], ['G01.249.335', 'G01.358.500.750'], ['E05.799.638.420', 'N06.850.810.370.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['J01.897.608'], ['E02.815.639'], ['E02.815.635... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Evidence-based paramedic models of care to reduce unnecessary emergency department attendance--feasibility and safety. | BACKGROUND: As demand for Emergency Department (ED) services continues to exceed increases explained by population growth, strategies to reduce ED presentations are being explored. The concept of ambulance paramedics providing an alternative model of care to the current default 'see and transport to ED' has intuitive a... | ['Allied Health Personnel', 'Emergency Service, Hospital', 'Evidence-Based Practice', 'Feasibility Studies', 'Health Services Misuse', 'Humans', 'Medical Audit', 'Models, Organizational', 'Patient Safety', 'Prospective Studies', 'Western Australia'] | 23,855,265 | [['M01.526.485.067', 'N02.360.067'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['H02.249'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['N02.421.380', 'N05.300.150.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05... | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Nitrate supplementation's improvement of 10-km time-trial performance in trained cyclists. | Six days of dietary nitrate supplementation in the form of beetroot juice (~0.5 L/d) has been reported to reduce pulmonary oxygen uptake (VO₂) during submaximal exercise and increase tolerance of high-intensity work rates, suggesting that nitrate can be a potent ergogenic aid. Limited data are available regarding the e... | ['Adult', 'Athletic Performance', 'Beta vulgaris', 'Beverages', 'Bicycling', 'Blood Glucose', 'Cross-Over Studies', 'Dietary Supplements', 'Double-Blind Method', 'Energy Intake', 'Humans', 'Insulin', 'Lactic Acid', 'Male', 'Nitrates', 'Oxygen Consumption', 'Performance-Enhancing Substances', 'Physical Endurance', 'Phys... | 22,248,502 | [['M01.060.116'], ['I03.450.642.845.054'], ['B01.650.940.800.575.912.250.200.399'], ['G07.203.100', 'J02.200'], ['I03.450.642.845.140'], ['D09.947.875.359.448.500'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.203.300.456', 'J02.500.456'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Formation of S-adenosylhomocysteine in the heart. I: An index of free intracellular adenosine. | To assess the concentration of free intracellular adenosine in the heart the kinetic properties of cytosolic S-adenosylhomocysteine (SAH) hydrolase were utilized at elevated levels of L-homocysteine (adenosine + L-homocysteine in equilibrium with SAH + H2O). Global hypoxia was induced in the isolated perfused guinea pi... | ['Adenosine', 'Animals', 'Guinea Pigs', 'Homocysteine', 'Intracellular Fluid', 'Myocardium', 'S-Adenosylhomocysteine'] | 3,383,378 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['B01.050.150.900.649.313.992.550'], ['D02.886.030.498', 'D12.125.166.498'], ['A11.284.430.429', 'A11.284.835.450', 'A12.207.515'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D02.886.030.498.050', 'D03.633.100.759.590.138.240', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of functional endonasal sinus surgery with and without partial middle turbinate resection. | The aim of endonasal sinus surgery is to ameliorate sinonasal symptoms and to achieve a functional nose. Although the importance of opening the ostiomeatal complex is accepted, the role of middle turbinate surgery remains controversial. Although some surgeons emphasize the importance of maintaining the middle turbinate... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Endoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Paranasal Sinuses', 'Postoperative Complications', 'Reoperation', 'Sinusitis', 'Turbinates'] | 10,903,043 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A04.531.621'], ['C23.550.767'], ['E04.690'], ['C01.748.749', 'C08.460.692.752', 'C08.730.749', 'C09.603.692.752'], ['A02.835.232.78... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A new preservation solution for lung transplantation: evaluation in a porcine transplantation model. | BACKGROUND: Lung preservation injury is still a major problem in lung transplantation. The aim of the current study was to evaluate the effects of a new preservation solution (Custodiol-N) for lung preservation.METHODS: Using an in vivo pig model, 7 lungs each were preserved for 24 hours after perfusion with: low-potas... | ['Animals', 'Blood Gas Analysis', 'Dextrans', 'Glucose', 'Hemodynamics', 'Lung', 'Lung Transplantation', 'Male', 'Models, Animal', 'Organ Preservation', 'Organ Preservation Solutions', 'Reperfusion Injury', 'Swine'] | 22,226,803 | [['B01.050'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D09.947.875.359.448'], ['G09.330.380'], ['A04.411'], ['E04.928.600.495', 'E04.936.450.495'], ['E05.598'], ['E02.792.833.660', 'E05.760.833.660'], ['D26.776.675'], ['C14.907.725', 'C23.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Emergency department workload increase: dependence on primary care? | BACKGROUND: Increasing demand for emergency care and crowded emergency departments (EDs) lead some planners to conclude that inconvenient primary care scheduling increases the number of "unnecessary" ED visits. The reasons that the planners argue for more primary care are: to increase funding for primary care; the unfo... | ['Cross-Sectional Studies', 'Emergency Service, Hospital', 'Health Care Surveys', 'Health Services Accessibility', 'Humans', 'Primary Health Care', 'Rural Population', 'West Virginia', 'Workload'] | 19,682,828 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.90... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
More than one way to see it: Individual heuristics in avian visual computation. | Comparative pattern learning experiments investigate how different species find regularities in sensory input, providing insights into cognitive processing in humans and other animals. Past research has focused either on one species' ability to process pattern classes or different species' performance in recognizing th... | ['Animals', 'Behavior, Animal', 'Columbidae', 'Discrimination Learning', 'Heuristics', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Psittaciformes', 'Reaction Time', 'Species Specificity', 'Visual Perception'] | 26,113,444 | [['B01.050'], ['F01.145.113'], ['B01.050.150.900.248.165.150'], ['F02.463.425.280'], ['F02.463.425.725.500', 'F02.463.785.810.500'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['B01.050.150.900.248.710'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['G16.824'], ['F02.463.593.932'... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Investigation of macrolide, lincosamide and streptogramin B resistance in Staphylococcus aureus strains isolated from clinical samples by phenotypical and genotypical methods]. | Staphylococcus aureus is one of the most common cause of both community and healthcare-associated infections. As staphylococci have developed resistance to various antibiotics, initially to penicillins then to methicillin and glycopeptides and have the ability to cause epidemics, they continue to be a major problem fro... | ['Anti-Bacterial Agents', 'Bacterial Proteins', 'Disk Diffusion Antimicrobial Tests', 'Genotype', 'Humans', 'Inpatients', 'Lincosamides', 'Macrolides', 'Methicillin-Resistant Staphylococcus aureus', 'Outpatients', 'Phenotype', 'Polymerase Chain Reaction', 'Random Amplified Polymorphic DNA Technique', 'Staphylococcal In... | 25,706,726 | [['D27.505.954.122.085'], ['D12.776.097'], ['E01.370.225.875.595.399', 'E05.200.875.595.399'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['D03.383.773.532', 'D09.408.471'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['B03.300.390.400.800.750.100.500', 'B03.353.500.750.75... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ATF2 predicts poor prognosis and promotes malignant phenotypes in renal cell carcinoma. | BACKGROUND: Activating transcription factor 2 (ATF2) is a basic helix-loop-helix transcription factor, which has been shown to participate in the pathobiology of numerous cancers. However, the role of ATF2 in renal cell carcinoma (RCC) remains unclear.METHODS: ATF2 knockdown and overexpression studies were performed in... | ['Activating Transcription Factor 2', 'Animals', 'Carcinoma, Renal Cell', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Cell Survival', 'Female', 'Gene Expression Regulation, Neoplastic', 'Gene Knockdown Techniques', 'Humans', 'Kidney Neoplasms', 'Male', 'Mice', 'Neoplasm Transplantation', '... | 27,377,902 | [['D12.776.260.108.061.750', 'D12.776.930.127.061.750'], ['B01.050'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Newborn first feed and prelacteal feeds in Mansoura, Egypt. | BACKGROUND: Prelacteal feed (feeding any other substance before first breastfeeding) appears to be common despite its harmful effects. By definition a child provided with prelacteal feed (PLF) is not exclusively breastfed and PLF has many implications for the success and early initiation of breastfeeding. Objectives. T... | ['Breast Feeding', 'Developing Countries', 'Educational Status', 'Egypt', 'Female', 'Humans', 'Infant Food', 'Infant, Newborn', 'Male', 'Prenatal Care', 'Rural Population', 'Social Class', 'Urban Population'] | 24,895,560 | [['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['I01.615.500.300'], ['N01.824.196'], ['Z01.058.266.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300.525.500', 'J02.500.525.500'], ['M01.060.703.520'], ['E02.760.786', 'N02.421.143.620.704', 'N02.421.585.786'... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Use of illicit drugs over gestation and their neonatal impact. Comparison between periods 1982-1988 and 2002-2008]. | BACKGROUND AND OBJECTIVE: The use of illicit drugs during pregnancy becomes a high risk situation. Our objective is to determine the currently prevalence, pregnancy, delivery and newborn's characteristics of mothers who use illicit drugs.PATIENTS AND METHODS: Retrospective study of children exposed prenatally to illici... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Illicit Drugs', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Pregnancy', 'Pregnancy Complications', 'Retrospective Studies', 'Substance-Related Disorders', 'Time Factors', 'Young Adult'] | 21,296,368 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['M01.060.703.520'], ['C16.614'], ['G08.686.784.769'], ['C13.703'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.85... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of dietary zinc restriction on postprandial changes in plasma zinc. | The principal objective of this study was to determine the effect of a short period of severe dietary zinc restriction on both prebreakfast and postbreakfast plasma zinc concentrations. After an overnight fast, plasma zinc was measured in five normal adults before and at 30-min intervals for 6 h after a standard zinc-f... | ['Adolescent', 'Adult', 'Diet', 'Eating', 'Humans', 'Middle Aged', 'Zinc'] | 8,237,878 | [['M01.060.057'], ['M01.060.116'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparative study of thin sectional anatomical images from Chinese visible human data set and computed tomography images of superior mediastinum. | The structures of superior mediastinum and their spatial relationships are complex and difficult to master. This study aimed to compare visualization of the superior mediastinum based on computed tomography (CT) images and on the thin sections of the Chinese visible human (CVH) data set to provide a sectional anatomica... | ['Adult', 'Asian Continental Ancestry Group', 'Cadaver', 'China', 'Diagnostic Imaging', 'Humans', 'Male', 'Mediastinal Diseases', 'Mediastinal Neoplasms', 'Mediastinum', 'Middle Aged', 'Tomography, Spiral Computed', 'Visible Human Projects'] | 22,334,507 | [['M01.060.116'], ['M01.686.508.200'], ['C23.550.260.224'], ['Z01.252.474.164'], ['E01.370.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.846.187'], ['C04.588.894.479', 'C08.846.187.580'], ['A01.923.761.800.500'], ['M01.060.116.630'], ['E01.370.350.350.810.800', 'E01.370.350.600.350.700.810.800', 'E01.37... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 |
Parent and caregiver perceptions about the safety and effectiveness of foreign and domestic vaccines in Shanghai, China. | BACKGROUND: Chinese parents have access to domestic and foreign vaccines for their children. Their vaccine preferences are unclear, especially given recent pharmaceutical quality scandals and widely held beliefs deriving from Traditional Chinese Medicine (TCM). This study characterized parental beliefs about the safety... | ['Caregivers', 'Child', 'Child, Preschool', 'China', 'Demography', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Infant', 'Male', 'Medicine, Chinese Traditional', 'Parents', 'Treatment Outcome', 'Vaccines'] | 29,782,508 | [['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['F01.82... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
KLK6 protease accelerates skin tumor formation and progression. | Kallikrein-related peptidase 6 (KLK6) is a serine protease that is aberrantly altered in various types of cancer, but its role in non-melanoma skin cancer has not been investigated. KLK6 is active in epidermis and has been linked to normal skin differentiation. Thus, we investigated whether it could be implicated in sk... | ['Animals', 'Carcinogenesis', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Cell Proliferation', 'Cytokines', 'Disease Progression', 'Epidermis', 'Inflammation', 'Kallikreins', 'Mice', 'Mice, Inbred C57BL', 'Papilloma', 'Skin', 'Skin Neoplasms'] | 30,137,206 | [['B01.050'], ['C04.697.098', 'C23.550.727.098'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C23.550.291.656'], ['A10.272.497', 'A17.815.250'], ['C23.550.470'], ['D08.811.277.656... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outcomes of unicompartmental knee arthroplasty stratified by body mass index. | Patients who have high body mass indices can have disabling medial compartment knee osteoarthritis, which might benefit from unicompartmental knee arthroplasty (UKA). The purpose of this study was to compare clinical and radiographic outcomes of UKAs in patients with body mass indices (BMIs) greater and less than 35 kg... | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Knee', 'Body Mass Index', 'Female', 'Follow-Up Studies', 'Humans', 'Knee Joint', 'Knee Prosthesis', 'Male', 'Middle Aged', 'Obesity', 'Osteoarthritis, Knee', 'Outcome Assessment, Health Care', 'Periprosthetic Fractures', 'Radiography', 'Retrospective Studies', '... | 21,256,695 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of health sector contingency plan in emergency preparedness and response: Orissa experiences. | A study was organized to orient the district level health sector disaster managers to review, revise and update the health sector contingency plan (HSCP) against common natural calamities, followed by its execution and evaluation. An inter-state 3 days workshop was organized at Kolkata during the month of October 2004 ... | ['Disaster Planning', 'Education', 'Emergency Medical Services', 'Health Care Sector', 'Humans', 'India', 'Organizational Case Studies'] | 20,108,889 | [['N06.230.100.035'], ['I02'], ['N02.421.297'], ['J01.576.489', 'N03.219.650'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['N03.349.380.710', 'N05.715.360.455']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
The x-ray time of flight method for investigation of ghosting in amorphous selenium-based flat panel medical x-ray imagers. | Amorphous selenium (a-Se) based real-time flat-panel imagers (FPIs) are finding their way into the digital radiology department because they offer the practical advantages of digital x-ray imaging combined with an image quality that equals or outperforms that of conventional systems. The temporal imaging characteristic... | ['Algorithms', 'Artifacts', 'Computer Simulation', 'Dose-Response Relationship, Radiation', 'Equipment Design', 'Equipment Failure Analysis', 'Models, Chemical', 'Radiation Dosage', 'Radiographic Image Interpretation, Computer-Assisted', 'Scattering, Radiation', 'Selenium', 'X-Ray Intensifying Screens', 'X-Rays'] | 16,279,070 | [['G17.035', 'L01.224.050'], ['E05.047'], ['L01.224.160'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['E05.320'], ['E05.325.192'], ['E05.599.495'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E01.158.600.680', 'E01.370.350.350.700', 'E01.370.350.700... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Changes in gut intramucosal pH and gut oxygen extraction ratio in a porcine model of peritonitis and hemorrhage. | OBJECTIVE: To establish the relationship between gut intramucosal pH and blood flow to the gut, gut oxygen delivery, and gut oxygen extraction ratio in a porcine model of peritonitis and hemorrhage.DESIGN: Prospective, controlled study.SETTING: Experimental laboratory in a university teaching hospital.SUBJECTS: Thirty ... | ['Animals', 'Disease Models, Animal', 'Female', 'Gastric Mucosa', 'Gastrointestinal Hemorrhage', 'Hemodynamics', 'Hydrogen-Ion Concentration', 'Intestinal Mucosa', 'Male', 'Manometry', 'Oxygen Consumption', 'Peritonitis', 'Prospective Studies', 'Swine'] | 7,587,264 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C06.405.227', 'C23.550.414.788'], ['G09.330.380'], ['G02.300'], ['A03.556.124.369', 'A10.615.550.444'], ['E05.559'], ['G03.680'], ['C01.463.600', 'C06.844.640'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.75... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Collagen osteoid-like model allows kinetic gene expression studies of non-collagenous proteins in relation with mineral development to understand bone biomineralization. | Among persisting questions on bone calcification, a major one is the link between protein expression and mineral deposition. A cell culture system is here proposed opening new integrative studies on biomineralization, improving our knowledge on the role played by non-collagenous proteins in bone. This experimental in v... | ['Animals', 'Apatites', 'Bone Matrix', 'Bone and Bones', 'Calcification, Physiologic', 'Cells, Cultured', 'Collagen', 'Gene Expression Regulation', 'Humans', 'Kinetics', 'Male', 'Middle Aged', 'Minerals', 'Models, Biological', 'Osteoblasts', 'Rats'] | 23,460,841 | [['B01.050'], ['D01.029.260.700.675.374.075.025', 'D01.146.360.050', 'D01.578.122', 'D01.695.625.675.650.075.025'], ['A10.165.265.166'], ['A02.835.232', 'A10.165.265'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G05.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lactose enhances cellulase production by the filamentous fungus Acremonium cellulolyticus. | Acremonium cellulolyticus is a fungus that produces cellulase and has been exploited by enzyme industry. To promote cellulase production by A. cellulolyticus strain C-1, we evaluated the effects of the saccharides: Solka Floc (cellulose), soluble soybean polysaccharide (SSPS), pullulan, lactose, trehalose, sophorose, c... | ['Acremonium', 'Cellulase', 'Culture Media', 'Enzyme Induction', 'Lactose'] | 18,804,052 | [['B01.300.381.025'], ['D08.811.277.450.420.200.200'], ['D27.720.470.305', 'E07.206'], ['G05.308.320.200'], ['D09.698.629.305.340', 'D09.947.750.340']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Porcine malignant hyperthermia: halothane effects on force generation in skeletal muscles. | Halothane-induced malignant hyperthermia (MH) is thought to result from a defect in the regulation of cytosolic calcium concentration in MH-susceptible (MHS) skeletal muscle. Such a defect might be expected to alter the time course of contractile responses. To test this hypothesis, isolated intact cell bundles from ext... | ['Animals', 'Calcium', 'Electric Stimulation', 'Halothane', 'Malignant Hyperthermia', 'Muscle Contraction', 'Muscles', 'Swine'] | 2,747,737 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.723.402'], ['D02.455.526.340'], ['C23.550.505.700', 'C23.550.767.600'], ['G11.427.494'], ['A02.633', 'A10.690'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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