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Tuning Cell Differentiation into a 3D Scaffold Presenting a Pore Shape Gradient for Osteochondral Regeneration. | Osteochondral regeneration remains nowadays a major problem since the outcome of current techniques is not satisfactory in terms of functional tissue formation and development. A possible solution is the combination of human mesenchymal stem cells (hMSCs) with additive manufacturing technologies to fabricate scaffolds ... | ['Adult', 'Bone Regeneration', 'Cartilage', 'Cell Differentiation', 'Humans', 'Male', 'Mesenchymal Stem Cells', 'Osteogenesis', 'Porosity', 'Tissue Scaffolds'] | 27,109,461 | [['M01.060.116'], ['G11.427.213.140', 'G16.762.150.150'], ['A02.165', 'A10.165.382'], ['G04.152'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['G01.374.710'], ['E07.206.627', 'E07.695.825']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessment of walking performance in robot-assisted gait training: a novel approach based on empirical data. | Motivation and voluntary drive of patients can be improved by applying biofeedback during robot-assisted rehabilitation trainings. Biofeedback systems were traditionally based on theoretical assumptions. In this paper, we present a novel approach to calculate biofeedback during robot-assisted gait training. Our method ... | ['Biofeedback, Psychology', 'Biomechanical Phenomena', 'Biomedical Engineering', 'Data Collection', 'Gait', 'Gait Disorders, Neurologic', 'Humans', 'Robotics', 'Walking'] | 19,163,079 | [['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['G01.154.090', 'G01.374.089'], ['H02.070', 'J01.293.140'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C10.597.404', 'C23.888.592.413'], ['B01.050.150.900.649.313.988.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 |
Muscarinic receptors involved in airway vascular leakage induced by experimental gastro-oesophageal reflux. | Gastro-oesophageal acid reflux may cause airway responses such as cough, bronchoconstriction and inflammation in asthmatic patients. Studies in humans or in animals have suggested that these responses involve cholinergic nerves. The purpose of this study was to investigate the role of the efferent vagal component on ai... | ['Animals', 'Atropine', 'Capillary Permeability', 'Diamines', 'Female', 'Ganglionic Blockers', 'Gastroesophageal Reflux', 'Guinea Pigs', 'Hexamethonium', 'In Vitro Techniques', 'Male', 'Muscarinic Antagonists', 'Nicotinic Antagonists', 'Parasympatholytics', 'Piperidines', 'Pirenzepine', 'Receptor, Muscarinic M1', 'Rece... | 18,367,213 | [['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['G03.143.330', 'G09.330.165'], ['D02.092.782.258'], ['D27.505.696.663.050.340'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.992.550'], ['D02.092.877.250.592... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Do Patients Feel Well Informed in a Radiation Oncology Service? | Information received by cancer patients has gained importance in recent decades. The aim of this study was to evaluate the perception of information received by oncological patients in a radiotherapy department and to measure the importance of the other information sources. A cross-sectional study was conducted, evalua... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Information Dissemination', 'Male', 'Middle Aged', 'Neoplasms', 'Patient Education as Topic', 'Patient Satisfaction', 'Quality of Life', 'Radiation Oncology', 'Surveys and Questionnaires'] | 27,655,176 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['M01.060.116.630'], ['C04'], ['I02.233.332.500', 'N02.421.726.407.680'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Disciplines and Occupations [H]'... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
[Neurofibroma of thyroid in a patient with neurofibromatosis type 1]. | The neurofibromatosis type 1 (NF1), also known as von Recklinghausens disease, is an autosomal dominant disorder, with high degree of variability of clinical expression, usually involved with formation of tumors, with benign origin in the majority of cases mainly localized in the region of the head and neck and rarely ... | ['Adult', 'Biopsy', 'Carcinoma, Medullary', 'Diagnosis, Differential', 'Female', 'Humans', 'Neurofibroma', 'Neurofibromatosis 1', 'Thyroid Gland', 'Thyroid Neoplasms', 'Thyroid Nodule'] | 18,345,407 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.465.625.650.240.315', 'C04.557.470.200.025.370.315', 'C04.557.470.615.315', 'C04.557.580.625.650.240.315'], ['E01.171'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The influence of stress on edentulous maxillary bone with different artificial anterior tooth arrangements by three-dimensional photoelasticity. | OBJECTIVE: To investigate the influence of stress on edentulous maxillary bone different artificial anterior tooth arrangements, with the goal to establish theoretical evidence for optimal anterior tooth arrangements in complete denture restoration.MATERIALS AND METHODS: Three-dimensional photoelasticity experimental s... | ['Alveolar Process', 'Birefringence', 'Dental Models', 'Dental Stress Analysis', 'Denture Design', 'Elasticity', 'Epoxy Resins', 'Humans', 'Incisor', 'Jaw, Edentulous', 'Maxilla'] | 10,557,172 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['G01.590.080'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['E06.308'], ['E06.780.346.760.300', 'E06.912.250'], ['G01.374.590'], ['D05.750.716.822.461', 'D25.720.716.822.461', 'J01.637.051.720.716.822.461'], ['B01.0... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Evaluation of an alternative fluorinated sorbent for dispersive solid-phase extraction clean-up of the quick, easy, cheap, effective, rugged, and safe method for pesticide residues analysis. | In this study, the efficiency of a new fluorinated sorbent for dispersive solid-phase extraction (d-SPE) clean-up in extracts provided by the QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) acetate method from tomato and sweet pepper samples was evaluated by ultra-high performance liquid chromatography tandem... | ['Adsorption', 'Amines', 'Chromatography, High Pressure Liquid', 'Fluoridation', 'Limit of Detection', 'Pesticide Residues', 'Silanes', 'Solid Phase Extraction', 'Soot', 'Tandem Mass Spectrometry'] | 28,774,714 | [['G01.030', 'G02.020'], ['D02.092'], ['E05.196.181.400.300'], ['E06.761.382', 'N06.890.235'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.200.700'], ['D01.837.700'], ['E05.196.155.800'], ['D20.633.937.339'], ['E05.196.566.880']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Design of Gaussia luciferase-based bioluminescent stem-loop probe for sensitive detection of HIV-1 nucleic acids. | Here we describe the design of a bioluminescent stem-loop probe for the sensitive detection of HIV-1 spliced RNA. In this study, we employed Gaussia luciferase (GLuc), a bioluminescent protein that has several advantages over other bioluminescent proteins, including smaller size, higher bioluminescent intensity, and ch... | ['Animals', 'Copepoda', 'HIV-1', 'Humans', 'Luciferases', 'Luminescent Proteins', 'RNA, Viral'] | 29,897,056 | [['B01.050'], ['B01.050.500.131.365.160'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.517', 'D12.776.532.510'], ['D12.776.532'], ['D13.444.735.828']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The complications of scar formation associated with intrathecal pump placement. | A 40-year-old man had an intrathecal morphine-baclofen pump inserted for the treatment of severe dystonia affecting all limbs and severe low back pain. The etiology of his dystonic symptoms, despite thorough investigations, was uncertain. At age 45, the patient fell resulting in a cervical spinal cord injury. He underw... | ['Adult', 'Analgesics, Opioid', 'Baclofen', 'Catheters, Indwelling', 'Cicatrix', 'Dystonia', 'Equipment Failure Analysis', 'Foreign-Body Migration', 'Humans', 'Infusion Pumps, Implantable', 'Injections, Spinal', 'Low Back Pain', 'Male', 'Morphine', 'Muscle Relaxants, Central'] | 17,321,835 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D02.241.081.114.500.350.100'], ['E07.132.500'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['C10.597.350.300', 'C23.888.592.350.300'], ['E05.325.192'], ['C26.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sinus rhythm mapping in healed experimental myocardial infarction: contrasting activation patterns for inducing ventricular tachycardia versus fibrillation. | The inducibility of ventricular tachycardia (VT) and fibrillation (VF) is variable in healed myocardial infarction (MI) in the dog. To better understand the electrophysiologic basis for these arrhythmias, MI was produced in dogs by ligating the left anterior descending artery. One week later, epicardial mapping was per... | ['Animals', 'Dogs', 'Electrocardiography', 'Electrophysiology', 'Myocardial Infarction', 'Tachycardia', 'Ventricular Fibrillation'] | 4,003,304 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.370.380.240', 'E01.370.405.240'], ['H01.158.344.528', 'H01.158.782.236'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845'], ['C14.280.067.922', 'C23.550.073... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A new variety of Salvia macrosiphon (Lamiaceae) for Iran. | In this study, Salvia macrosiphon Boiss. var. longiflora Kharaz. is reported for the first time as one of the new varieties of Salvia macrosiphon in Iran. The morphological characters of this variety have been described in details. | ['Ecosystem', 'Geography', 'Iran', 'Salvia'] | 18,819,561 | [['G16.500.275.157', 'N06.230.124'], ['H01.277.500'], ['Z01.252.245.500.350'], ['B01.650.940.800.575.912.250.583.520.922']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Prognostic factors for venous thrombosis in patients with peripherally inserted central catheters: Protocol for a systematic review and meta-analysis. | BACKGROUND: Peripherally inserted central catheters (PICCs) has become increasingly popular in clinical practice because of the ease and safety of insertion and lower cost-effectiveness. The precise incidence and risk of PICC-related venous thrombosis is important to be verified in the context of growing PICC use and a... | ['Catheterization, Peripheral', 'Humans', 'Prognosis', 'Research Design', 'Risk Assessment', 'Risk Factors', 'Venous Thrombosis'] | 32,664,112 | [['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['E05.581.500', 'H01.770.644.728'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['E05.318.740.600.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
SB-216763, a GSK-3â inhibitor, protects against aldosterone-induced cardiac, and renal injury by activating autophagy. | Cardiovascular and renal inflammation induced by Aldosterone (Aldo) plays a pivotal role in the pathogenesis of hypertension and renal fibrosis. GSK-3â contributes to inflammatory cardiovascular and renal diseases, but its role in Aldo-induced hypertension, and renal damage is not clear. In the present study, rats were... | ['Aldosterone', 'Animals', 'Autophagy', 'Cytokines', 'Fibrosis', 'Glycogen Synthase Kinase 3 beta', 'Heart Diseases', 'Indoles', 'Inflammation', 'Kidney Diseases', 'Male', 'Maleimides', 'Rats', 'Rats, Wistar'] | 29,600,538 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['B01.050'], ['G04.011'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C23.550.355'], ['D05.500.117.875.500', 'D08.811.913.696.620.682.700.429.500.500', 'D08.811.913.696.620.682.700.646.625.500', 'D12.644.360.300.500.500', 'D12.776.476.081.875.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and characterization of insulin-transferrin conjugates. | Receptor-mediated endocytosis can be exploited for improving the transcellular delivery of therapeutic proteins. Insulin conjugated to transferrin by forming disulfide bonds has been shown to improve insulin oral bioavailability in diabetic rats. We are developing a combination strategy involving complexation hydrogels... | ['Amines', 'Chromatography, High Pressure Liquid', 'Fluorescamine', 'Insulin', 'Molecular Sequence Data', 'Molecular Structure', 'Spectrometry, Mass, Electrospray Ionization', 'Transferrin'] | 17,105,214 | [['D02.092'], ['E05.196.181.400.300'], ['D02.455.426.779.345', 'D03.633.100.127.218', 'D04.711.345'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['E05.196.566.600'], ['D12.776.124.050.800', 'D12.776.124.790.223.839', 'D12.776.157.427.750.500', 'D12.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Modeling variation in early life mortality in the western lowland gorilla: Genetic, maternal and other effects. | Uncovering sources of variation in gorilla infant mortality informs conservation and life history research efforts. The international studbook for the western lowland gorilla provides information on a sample of captive gorillas large enough for which to analyze genetic, maternal, and various other effects on early life... | ['Animal Husbandry', 'Animals', 'Animals, Zoo', 'Female', 'Gorilla gorilla', 'Humans', 'Linear Models', 'Male', 'Mortality', 'Parity', 'Paternal Age', 'Pregnancy'] | 25,809,396 | [['J01.040.090'], ['B01.050'], ['B01.050.050.448'], ['B01.050.150.900.649.313.988.400.112.400.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.42... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Toothbrush-thinking seizures. | Seizures associated with toothbrushing have been reported in patients with precentral or postcentral partial epilepsy. Seizures precipitated by thinking have been described in patients with idiopathic generalized epilepsy. We report a patient with intractable partial epilepsy in which seizures were induced both by toot... | ['Electroencephalography', 'Epilepsies, Partial', 'Epilepsy, Reflex', 'Epilepsy, Temporal Lobe', 'Functional Laterality', 'Humans', 'Male', 'Middle Aged', 'Thinking', 'Toothbrushing', 'Toothpastes', 'Videotape Recording'] | 17,116,043 | [['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360'], ['C10.228.140.490.450'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.785'], ['E06.761.726.794'], ['D25.376.711', 'J01.637.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Complications of lumboperitoneal shunts. | OBJECTIVE: Placement of a lumboperitoneal (LP) shunt is a method for treating communicating hydrocephalus. These shunts can be placed with or without valves. We sought to review the complications associated with the use of LP shunts with the increasing use of horizontal-vertical (HV) valve systems.PATIENTS AND METHODS:... | ['Adolescent', 'Adult', 'Cerebrospinal Fluid Shunts', 'Child', 'Equipment Design', 'Equipment Failure', 'Female', 'Follow-Up Studies', 'Humans', 'Intracranial Hypertension', 'Male', 'Middle Aged', 'Reoperation', 'Retrospective Studies', 'Treatment Outcome'] | 17,538,378 | [['M01.060.057'], ['M01.060.116'], ['E04.035.188', 'E04.525.170'], ['M01.060.406'], ['E05.320'], ['E05.325'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.631'], ['M01.060.116.630'], ['E04.690'], ['E05.318.372.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel phenotype for Lardon dwarfism in miniature Bos indicus cattle suggests that the expression of growth hormone receptor 1A in liver is required for normal growth. | Mutations within the growth hormone receptor (GHR) gene that lead to an inactivated or truncated GHR protein cause abnormal growth and small adult size in a variety of species (Laron dwarfism). We studied a line of miniature Bos indicus cattle that have phenotypic (small mature size) and endocrine (increased blood grow... | ['Animals', 'Blotting, Northern', 'Cattle', 'Cattle Diseases', 'Dwarfism', 'Insulin-Like Growth Factor I', 'Liver', 'Mutation', 'Phenotype', 'RNA, Messenger', 'Receptors, Somatotropin'] | 10,628,432 | [['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C05.116.099.343', 'C16.320.240', 'C19.297'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['A03.620'], ['G05.365.590'], ['G05.695'], ['D13.444.735.544... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dermatofibroma with granular cells. | A new histologic variant of dermatofibroma, only briefly alluded to in dermatological literature is reported. This tumor was located in the back of a 24-year-old man. It was present for about 2 years and had a history of trauma 2 months before excision. The lesion showed similar characteristics to those of conventional... | ['Adult', 'Back', 'Diagnosis, Differential', 'Histiocytoma, Benign Fibrous', 'Humans', 'Immunohistochemistry', 'Male', 'Skin Neoplasms'] | 9,001,988 | [['M01.060.116'], ['A01.923.176'], ['E01.171'], ['C04.557.450.565.590.425.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', '... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Symposium: animal food safety and dairy regulations, now and in the future. Animal food safety and dairy regulations, now and in the future: from farm to fork, a state perspective. | The enforcement of dairy and food safety regulations has fallen most heavily on the states in the past, and this responsibility will no doubt continue, and even expand, in the future. States must be concerned not only about their own state laws but also about the impact of increasing federal regulations. The protection... | ['Dairying', 'Legislation, Food', 'United States', 'United States Department of Agriculture', 'United States Food and Drug Administration'] | 7,622,730 | [['J01.040.246'], ['N03.706.615.412'], ['Z01.107.567.875'], ['I01.409.418.750.400', 'N03.540.348.500.500.400'], ['I01.409.418.750.600.650.760', 'N03.540.348.500.500.600.650.760']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Effects of angiotensin-converting enzyme inhibitors and sclerotherapy on portal hemodynamics in patients with portal hypertension. | BACKGROUND/AIMS: Since pharmacotherapy of portal hypertension has always been a subject of wide interest, we decided to study the effects of different angiotensin-converting enzyme inhibitors and endoscopic sclerotherapy on portal hemodynamics in patients with portal hypertension and bleeding esophageal varices.METHODO... | ['Adult', 'Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Endoscopy', 'Esophageal and Gastric Varices', 'Female', 'Hemodynamics', 'Humans', 'Hypertension, Portal', 'Lisinopril', 'Male', 'Middle Aged', 'Portal System', 'Portal Vein', 'Sclerotherapy', 'Ultrasonography, Doppler, Duplex'] | 10,919,035 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.389.745.085'], ['E01.370.388.250', 'E04.502.250'], ['C06.405.117.240', 'C06.552.494.414'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['D12.644.456.345.600'], ['M01.060.116.630'], ['A07.015.908.670'], ['A07.015.908.670.567'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains. | Therapeutics that target ERBB2, such as lapatinib, often provide initial clinical benefit, but resistance frequently develops. Adaptive responses leading to lapatinib resistance involve reprogramming of the kinome through reactivation of ERBB2/ERBB3 signaling and transcriptional upregulation and activation of multiple ... | ['Antineoplastic Agents', 'Blotting, Western', 'Breast Neoplasms', 'Cell Line, Tumor', 'Drug Resistance, Neoplasm', 'Female', 'Humans', 'Lapatinib', 'Mass Spectrometry', 'Oligonucleotide Array Sequence Analysis', 'Polymerase Chain Reaction', 'Protein Kinase Inhibitors', 'Proteomics', 'Quinazolines', 'Receptor, ErbB-2',... | 25,865,888 | [['D27.505.954.248'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.786.516'], ['E05.196.566'], ['E05... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Oncostatin M and leukemia inhibitory factor increase hepcidin expression in hepatoma cell lines. | Overproduction of hepcidin by interleukin-6 (IL-6) is considered to be the main factor responsible for the development of anemia in inflammatory conditions. Since oncostatin M (OSM), a member of the IL-6 family, plays an important role in immune and inflammatory responses, we assessed the effect of OSM on hepcidin expr... | ['Antimicrobial Cationic Peptides', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Dose-Response Relationship, Drug', 'Hepcidins', 'Humans', 'Leukemia Inhibitory Factor', 'Oncostatin M'] | 19,915,946 | [['D12.644.050', 'D12.776.543.695.054'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.494.249', 'D12.776.543.695.054.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.27... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pilot plant study of alternative filter media for rapid gravity filtration. | Sand has been the main filter media used in rapid gravity filtration since its introduction. The dominance of sand has been due to its low cost and availability. Extensive experience has led to sand filters with a dependable and predictable performance. Sand remains the preferred filter medium but usually with a larger... | ['Filtration', 'Gravitation', 'Nephelometry and Turbidimetry', 'Particle Size', 'Pilot Projects', 'Rheology', 'Water Purification'] | 23,109,598 | [['E05.196.454', 'G01.280', 'G02.263'], ['G01.060.350'], ['E05.196.712.650'], ['G02.712'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.830', 'H01.671.808'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Degradation properties of chitosan microspheres/poly(L-lactic acid) composite in vitro and in vivo. | Poly(L-lactic acid) (PLLA) is a popular biodegradable polymer, but the accumulated acid production by degradation is a bottleneck for its extended utilization. In this study, chitosan microspheres (CSMs) were introduced into PLLA porous matrices to manipulate the acid microclimate from PLLA degradation. In vitro and in... | ['Animals', 'Biocompatible Materials', 'Chitosan', 'Hydrogen-Ion Concentration', 'Injections, Subcutaneous', 'Microspheres', 'Particle Size', 'Polyesters', 'Porosity', 'Rats', 'Surface Properties'] | 29,773,361 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D05.750.078.139.500', 'D09.698.211.500'], ['G02.300'], ['E02.319.267.530.620'], ['E07.565'], ['G02.712'], ['D05.750.728', 'D25.720.728', 'J01.637.051.720.728'], ['G01.374.710'], ['B01.050.150.900.649.313.992.635.505.700'], ['G02.860']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The 10K virion phosphoprotein encoded by gene US9 from herpes simplex virus type 1. | Gene US9 of herpes simplex virus type 1 has been predicted, from DNA sequence analysis, to encode a protein of mol wt 10,026, designated 10K (D.J. McGeoch, A. Dolan, S. Donald, and F.J. Rixon (1985). J. Mol. Biol. 181, 1-13). We have investigated this protein by using a synthetic peptide corresponding to the 11 amino a... | ['Animals', 'Cricetinae', 'Electrophoresis, Polyacrylamide Gel', 'Intracellular Signaling Peptides and Proteins', 'Lipoproteins', 'Microscopy, Electron', 'Molecular Weight', 'Phosphoproteins', 'Protein Biosynthesis', 'Rabbits', 'Simplexvirus', 'Viral Proteins', 'Virion'] | 3,008,413 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.644.360', 'D12.776.476'], ['D10.532', 'D12.776.521'], ['E01.370.350.515.402', 'E05.595.402'], ['G02.494'], ['D12.776.744'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['B01.050.150.900.649.313.968.700'], ['B... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluorescence anisotropy imaging microscopy maps calmodulin binding during cellular contraction and locomotion. | Calmodulin is a calcium transducer that activates key regulatory and structural proteins through calcium-induced binding to the target proteins. A fluorescent analog of calmodulin in conjunction with ratio imaging, relative to a volume indicator, has demonstrated that calmodulin is uniformly distributed in serum-depriv... | ['3T3 Cells', 'Actin Cytoskeleton', 'Animals', 'Calcium', 'Calmodulin', 'Calmodulin-Binding Proteins', 'Cell Movement', 'Cell Size', 'Cells, Cultured', 'Cytoplasm', 'Fluorescence Polarization', 'Image Processing, Computer-Assisted', 'In Vitro Techniques', 'Mice', 'Motion', 'Myosin-Light-Chain Kinase', 'Myosins', 'Visco... | 8,501,117 | [['A11.251.210.100', 'A11.329.228.100'], ['A11.284.430.214.190.750.050'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D12.776.157.142'], ['G04.198', 'G07.568.500.180'], ['G04.325'], ['A11.251'], ['A11.284.430.214'], ['E... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection. | To determine the patient-dependent and virus-related factors that may predict sustained response to interferon-alpha therapy, we prospectively evaluated 60 consecutive patients with chronic hepatitis C who received a standardized treatment schedule of interferon-alpha. Twenty-eight patients achieved a long-term sustain... | ['Adult', 'Aged', 'Base Sequence', 'Chronic Disease', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Interferon-alpha', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Multivariate Analysis', 'Polymerase Chain Reaction', 'Predictive Value of Tests', 'Prospective Studies', 'Remissio... | 8,175,130 | [['M01.060.116'], ['M01.060.116.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C23.550.291.500'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Study on association between an H-RAS gene polymorphism and gastric cancer development]. | BACKGROUND/AIMS: Oncogenic RAS gene mutations have been frequently observed in many tumor types, and their associations with various cancers were reported. This study was conducted to evaluate the association between H-RAS T81C polymorphism and gastric cancer development.METHODS: H-RAS T81C polymorphism was genotyped i... | ['Adult', 'Aged', 'Alleles', 'Amino Acid Substitution', 'Chronic Disease', 'Female', 'Gastritis', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Republic of Korea', 'Stomach Neoplasms', 'ras Proteins'] | 20,729,618 | [['M01.060.116'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['E05.393.420.601.035', 'G05.558.109'], ['C23.550.291.500'], ['C06.405.205.697', 'C06.405.748.398'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Analysis of the palmitoylation and membrane targeting domain of neuromodulin (GAP-43) by site-specific mutagenesis. | Neuromodulin (GAP-43) is a neurospecific calmodulin binding protein which is implicated in neuronal growth and regeneration. It is concentrated in neuronal growth cones and associates with membranes through the palmitoylation of the N-terminal peptide MLCCMRRTK at Cys-3 and Cys-4. In the present study, we have identifi... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Line', 'Cell Membrane', 'Chlorocebus aethiops', 'Cloning, Molecular', 'Cytosol', 'DNA Primers', 'Electrophoresis, Polyacrylamide Gel', 'Fluorescent Antibody Technique', 'GAP-43 Protein', 'Kidney', 'Kinetics', 'Membrane Glycoproteins', 'Mice', 'Molecular Sequence... | 8,399,217 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['A11.284.149'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.393.220'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D13.695.578.424.450.27... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Anuria, cholestatic jaundice, thrombocytopenia, hemolysis. Immunoallergic complication due to ajmaline]. | A 75 year old man, treated with ajmaline, was admitted with malaise, fever, acute renal failure and cholestatic jaundice. Haemolytic anaemia and thrombocytopaenia were also found with a positive indirect Coomb's test in the presence of ajmaline. The immunological and haematological data are discussed in the light of pr... | ['Aged', 'Ajmaline', 'Anemia, Hemolytic', 'Anuria', 'Cholestasis', 'Drug Hypersensitivity', 'Humans', 'Male', 'Thrombocytopenia'] | 4,062,136 | [['M01.060.116.100'], ['D03.132.436.681.077', 'D03.633.100.473.402.681.077', 'D03.633.100.496.500.500.681.077'], ['C15.378.071.141'], ['C12.777.419.078', 'C12.777.934.141', 'C13.351.968.419.078', 'C13.351.968.934.070'], ['C06.130.120.135'], ['C20.543.206', 'C25.100.468'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Diabetic emergencies: hypoglycemia and ketoacidosis. | Because hypoglycemia may be rapidly fatal it must be diagnosed and treated early. Ketoacidosis may be difficult to differentiate from hypoglycemia. The diagnosis, treatment and causes of both diabetic emergencies are described. Once rehydration is instituted, further management can be directed using appropriate laborat... | ['Diabetes Complications', 'Diabetic Ketoacidosis', 'Emergencies', 'Humans', 'Hypoglycemia', 'Insulin', 'Osmolar Concentration'] | 819,702 | [['C19.246.099'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G02.640']] | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
HANN: A Hybrid Model for Liver Syndrome Classification by Feature Assortment Optimization. | Early detection of any sort of disease is mandatory for effective medical treatment. Medical diagnosis relies heavily on Data Mining for automated disease classification and detection. It relies on data mining algorithms to examine medical data. Liver diseases have become more common these days with many new patients b... | ['Algorithms', 'Data Mining', 'Humans', 'Liver Diseases', 'Neural Networks, Computer'] | 30,259,179 | [['G17.035', 'L01.224.050'], ['L01.313.500.750.280.199', 'L01.470.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['G17.485', 'L01.224.050.375.605']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Bacterial Biofilm Bioinspired Persistent Luminescence Nanoparticles with Gut-Oriented Drug Delivery for Colorectal Cancer Imaging and Chemotherapy. | Colorectal cancer (CRC) is now one of the leading causes of cancer incidence and mortality. Although nanomaterial-based drug delivery has been used for the treatment of colorectal cancer, inferior targeting ability of existing nanocarriers leads to inefficient treatment and side effects. Moreover, the majority of intra... | ['Animals', 'Biofilms', 'Cell Line', 'Cell Line, Tumor', 'Cell Survival', 'Colorectal Neoplasms', 'Diagnostic Imaging', 'Drug Delivery Systems', 'Drug Liberation', 'Fluorouracil', 'Gastrointestinal Tract', 'Humans', 'Luminescence', 'Mice', 'Nanoparticles', 'Silicon Dioxide', 'X-Ray Diffraction'] | 31,525,949 | [['B01.050'], ['A20.593', 'G06.120'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.370.350'], ['E02.319.300'], ['G02.211', 'G03.787.321', 'G07.69... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Short-term dynamics of isotopic composition of leaf-respired CO2 upon darkening: measurements and implications. | Recent advances in understanding the metabolic origin and the temporal dynamics in delta(13)C of dark-respired CO(2) (delta(13)C(res)) have led to an increasing awareness of the importance of plant isotopic fractionation in respiratory processes. Pronounced dynamics in delta(13)C(res) have been observed in a number of ... | ['Carbohydrate Metabolism', 'Carbon Dioxide', 'Carbon Isotopes', 'Darkness', 'Photosynthesis', 'Plant Development', 'Plant Leaves', 'Plants'] | 19,603,472 | [['G02.111.158', 'G03.191'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.268.150.075', 'D01.496.123'], ['G01.590.540.233'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['G07.345.625', 'G15.589'], ['A18.024.812'], ['B01.650']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polyphenol metabolism in differently colored cultivars of red currant (Ribes rubrum L.) through fruit ripening. | MAIN CONCLUSION: Rare red currants colors caused by low anthocyanin content in the pink and a lack of anthocyanins in the white cultivar correlated with low ANS gene expression, enzyme activity, and increased sugar/acid ratios. Changes in the contents of polyphenols, sugars, and organic acids in berries of the three di... | ['Acyltransferases', 'Anthocyanins', 'Fruit', 'Gene Expression Regulation, Plant', 'Mixed Function Oxygenases', 'Oxidoreductases', 'Oxygenases', 'Plant Proteins', 'Polyphenols', 'Ribes'] | 28,315,000 | [['D08.811.913.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G05.308.375'], ['D08.811.682.690.708'], ['D08.811.682'], ['D08.811.682.690'], ['D12.776.765'], ['D02.455.426.559.389.657.715', 'D03.633.100.150.266.450... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Enhancement of the CO(2) retention capacity of X zeolites by Na- and Cs-treatments. | Adsorption of carbon dioxide on alkaline modified X zeolites was investigated by temperature programmed desorption (TPD) analysis of these materials previously saturated with CO(2) at 50, 100 and 200 degrees C. Parent X zeolite (in its sodium form) was treated with different sodium and cesium aqueous solutions, using b... | ['Adsorption', 'Carbon Dioxide', 'Cesium', 'Sodium', 'Temperature', 'X-Ray Diffraction', 'Zeolites'] | 17,977,576 | [['G01.030', 'G02.020'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.268.549.125', 'D01.268.556.165', 'D01.552.528.160', 'D01.552.544.165'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Diurnal and ultradian rhythmicity of plasma leptin: effects of gender and adiposity. | Plasma leptin shows a nocturnal rise and a pulsatile pattern. This work was undertaken to determine the effects of gender and obesity on this pattern. Twenty-four-hour leptin profiles were evaluated in 31 subjects [17 male, 14 female; age: 36 +/- 2 yr (mean +/- SEM); body mass index: 27.5 +/- 1.0 kg/m2]. Plasma leptin ... | ['Adipose Tissue', 'Adolescent', 'Adult', 'Aging', 'Body Composition', 'Body Constitution', 'Body Mass Index', 'Circadian Rhythm', 'Female', 'Humans', 'Insulin', 'Leptin', 'Male', 'Middle Aged', 'Obesity', 'Proteins', 'Sex Characteristics'] | 9,467,557 | [['A10.165.114'], ['M01.060.057'], ['M01.060.116'], ['G07.345.124'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115', 'G07.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.69... | ['Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antibiotic resistance, plasmid-mediated quinolone resistance (PMQR) genes and ampC gene in two typical municipal wastewater treatment plants. | Antibiotic resistant bacteria and plasmid-mediated quinolone resistance genes and ampC gene were investigated for Escherichia coli isolates from two typical municipal wastewater treatment plants in both dry and wet seasons by using the antibiotic susceptibility test and PCR assay, respectively. The results showed that ... | ['Bacterial Proteins', 'Drug Resistance, Microbial', 'Genes, Bacterial', 'Waste Disposal Facilities', 'Waste Disposal, Fluid', 'Waste Water', 'Water Microbiology', 'beta-Lactamases'] | 24,441,525 | [['D12.776.097'], ['G06.225', 'G07.690.773.984.269'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['N06.850.780.200.800.800.900.449', 'N06.850.860.510.900.700'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.710.865'], ['H01.158.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Assessment of three-dimensional high-definition visualization technology to perform microvascular anastomosis. | BACKGROUND AND AIM: Traditional visualization techniques in microsurgery require strict positioning in order to maintain the field of visualization. However, static posturing over time may lead to musculoskeletal strain and injury. Three-dimensional high-definition (3DHD) visualization technology may be a useful adjunc... | ['Anastomosis, Surgical', 'Animals', 'Attitude of Health Personnel', 'Ergonomics', 'Femoral Artery', 'General Surgery', 'Humans', 'Imaging, Three-Dimensional', 'Internship and Residency', 'Male', 'Microsurgery', 'Microvessels', 'Musculoskeletal Diseases', 'Occupational Diseases', 'Posture', 'Rats', 'Rats, Sprague-Dawle... | 24,838,275 | [['E04.035'], ['B01.050'], ['F01.100.050', 'N05.300.100'], ['F02.784.412', 'J01.293.556'], ['A07.015.114.351'], ['H02.403.810.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['E04.494', 'E05.591.580'], ['A07.015.461'], ['C05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomen... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
The major histocompatibility complex of rhesus monkeys. VIII. Isolation and partial characterization of SD antigens. | The structure and chemical nature of the serologically defined (SD) antigens coded by the major histocompatibility complex (RhLA) of rhesus monkeys was studied. The use of specific anti-SD sera allowed the selective isolation of the corresponding antigens from crude antigen preparations. These were obtained by detergen... | ['Animals', 'Genes, MHC Class II', 'Haplorhini', 'Histocompatibility Antigens', 'Lymphocytes', 'Macaca', 'Macaca mulatta', 'Male', 'Molecular Weight', 'Peptides'] | 417,437 | [['B01.050'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['B01.050.150.900.649.313.988.400'], ['D23.050.301.500', 'D23.050.705.552'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['B01.050.150.900.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis of health insurance data on home nursing care in Hungary]. | INTRODUCTION: Home nursing care was introduced in Hungary in 1996.AIM: The aim of this study was to analyse health insurance data and utilization indicators of the Hungarian home nursing care.METHOD: Data derived from the database of the National Health Insurance Fund Administration (2001-2012). The number of patients ... | ['Healthcare Disparities', 'Home Nursing', 'Humans', 'Hungary', 'Insurance, Health', 'Socioeconomic Factors'] | 24,704,772 | [['N04.590.374.380', 'N05.300.493'], ['E02.760.611.470', 'N02.421.143.524.470', 'N02.421.533.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['N03.219.521.576.343'], ['I01.880.853.996', 'N01.824']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Appraisal of control and coping with air-raids. | This study investigated the appraisal of control (secondary appraisal) and coping as reactions to the air-raids in the city of Zagreb. Coping was assessed with the Croatian version of Ways of Coping (Lazarus & Folkman, 1984) and secondary appraisal was operationalized as control over the occurrence and over the outcome... | ['Adaptation, Psychological', 'Adult', 'Croatia', 'Emotions', 'Female', 'Habituation, Psychophysiologic', 'Humans', 'Internal-External Control', 'Male', 'Problem Solving', 'Stress, Psychological', 'Students', 'Universities', 'Urban Health', 'Warfare'] | 8,731,550 | [['F01.058'], ['M01.060.116'], ['Z01.542.248.295'], ['F01.470'], ['F02.463.425.393', 'F02.830.422', 'G11.561.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F02.463.425.725', 'F02.463.785.810'], ['F01.145.126.990', 'F02.830.900'], ['M01.848'], ['I02.783.830', 'J03.832.830'], ['N01.400.548.875... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
[Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense]. | OBJECTIVE: To investigate the chemical constituents of 70% aqueous ethanol extract from the whole plant of Crossostephium chinense for inhibitory activity against alpha-glucosidase.METHOD: A bioactivity-guided isolation and purification process was used to identify the alpha-glucosidase activity inhibiting components o... | ['Asteraceae', 'Enzyme Inhibitors', 'Glycoside Hydrolase Inhibitors', 'Kinetics', 'Plant Extracts', 'Protein Binding', 'alpha-Glucosidases'] | 19,943,487 | [['B01.650.940.800.575.912.250.100'], ['D27.505.519.389'], ['D27.505.519.389.320', 'D27.505.696.422.249'], ['G01.374.661', 'G02.111.490'], ['D20.215.784.500', 'D26.667'], ['G02.111.679', 'G03.808'], ['D08.811.277.450.420.050']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Natural organic matter (NOM) and pesticides removal using a combination of ion exchange resin and powdered activated carbon (PAC). | The combination of anion exchange resins (AERs) and powdered activated carbon (PAC) was studied to remove both natural organic matter (NOM) and pesticides. Experiments were conducted with high dissolved organic carbon (DOC) surface water (about 6.0mg DOC/L) spiked with both atrazine and isoproturon. AERs, like MIEX and... | ['Adsorption', 'Carbon', 'Ion Exchange Resins', 'Kinetics', 'Organic Chemicals', 'Pesticides'] | 18,006,038 | [['G01.030', 'G02.020'], ['D01.268.150'], ['D27.720.470.420'], ['G01.374.661', 'G02.111.490'], ['D02'], ['D27.720.031.700', 'D27.888.723']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterizing relationships among fecal indicator bacteria, microbial source tracking markers, and associated waterborne pathogen occurrence in stream water and sediments in a mixed land use watershed. | Bed sediments of streams and rivers may store high concentrations of fecal indicator bacteria (FIB) and pathogens. Due to resuspension events, these contaminants can be mobilized into the water column and affect overall water quality. Other bacterial indicators such as microbial source tracking (MST) markers, developed... | ['Bacteria', 'Feces', 'Water', 'Water Microbiology', 'Water Pollution'] | 27,295,624 | [['B03'], ['A12.459'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['N06.850.460.790']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Cellular interactions between n-6 and n-3 fatty acids: a mass analysis of fatty acid elongation/desaturation, distribution among complex lipids, and conversion to eicosanoids. | The biologic effect of eicosanoids depends in large measure upon the relative masses in tissues of eicosanoids derived from the n-6 fatty acids, dihomogammalinolenic acid and arachidonic acid, and the n-3 fatty acid, eicosapentaenoic acid. Generation of this tissue balance is related to the relative cellular masses of ... | ['8,11,14-Eicosatrienoic Acid', 'Animals', 'Arachidonic Acid', 'Carbon Radioisotopes', 'Cells, Cultured', 'Eicosanoids', 'Eicosapentaenoic Acid', 'Fatty Acids', 'Fatty Acids, Omega-3', 'Fatty Acids, Omega-6', 'Fatty Acids, Unsaturated', 'Mice', 'Phospholipids', 'Prostaglandins'] | 1,472,257 | [['D10.251.355.255.207'], ['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.251'], ['D10.251.355.255', 'D23.469.050.175'], ['D10.212.302.380.410.385', 'D10.251.355.255.200', 'D10.251.355.337.290', 'D10.627.430.450.390'], ['D10.251']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel aspects of the structure of the Escherichia coli nucleoid investigated by a rapid sedimentation assay. | The Escherichia coli nucleoid is maintained in its folded highly condensed state by constraints which involve RNA and protein. We have developed a rapid sedimentation assay to determine the state of folding of the membrane-free nucleoid. An approximate measure of the stability of the nucleoids under various conditions ... | ['Bacterial Proteins', 'DNA, Bacterial', 'DNA, Superhelical', 'Escherichia coli', 'Ethidium', 'Gamma Rays', 'Models, Biological', 'Nucleic Acid Heteroduplexes', 'RNA, Bacterial', 'Temperature'] | 6,184,141 | [['D12.776.097'], ['D13.444.308.212'], ['D13.444.308.283.250', 'G02.111.570.820.486.212.250', 'G05.360.580.156.250'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D03.633.300.633.416'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['E05.599.395'], ['D13.444.500'], ['D13.444.735.473'], ['G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Health care utilization in the British National Health Service. | Four national surveys of primary care services in England and Wales demonstrate that utilization rates have not continued to increase significantly since the initiation of the National Health Service in 1948, despite an initial surge in demands for medical services. The author examines morbidity surveys, consultation p... | ['Dental Staff, Hospital', 'England', 'Health Care Surveys', 'Health Services Research', 'Health Surveys', 'Home Care Services', 'Humans', 'Medical Staff, Hospital', 'Morbidity', 'Operations Research', 'Physicians, Family', 'Primary Health Care', 'Referral and Consultation', 'State Medicine', 'Wales'] | 10,165,630 | [['M01.526.485.290.490', 'M01.526.485.740.322', 'N02.360.290.490', 'N02.360.740.322'], ['Z01.542.363.300'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
High-resolution ultrasound confirms reduced synovial hyperplasia following rituximab treatment in rheumatoid arthritis. | OBJECTIVE: To assess the response of RA patients to rituximab (RTX) treatment using a sensitive imaging technique for synovitis.METHODS: Twenty-three RA patients were treated with two 1000-mg infusions of the B-cell depleting antibody, RTX, in an observational protocol. Clinical response was assessed by the European Le... | ['Adult', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Murine-Derived', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Female', 'Finger Joint', 'Follow-Up Studies', 'Humans', 'Hyperplasia', 'Male', 'Middle Aged', 'Rituximab', 'Severity of Illness Index', 'Statistics, Nonparametric', 'Synovial Membrane', 'Treat... | 19,491,302 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A02.835... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition. | Recognition of the methyl-7-guanosine (m(7)G) cap structure on mRNA is an essential feature of mRNA metabolism and thus gene expression. Eukaryotic translation initiation factor 4E (eIF4E) promotes translation, mRNA export, proliferation, and oncogenic transformation dependent on this cap-binding activity. eIF4E-cap re... | ['Amino Acid Sequence', 'Animals', 'Biophysical Phenomena', 'Cell Transformation, Neoplastic', 'Conserved Sequence', 'Eukaryotic Initiation Factor-4E', 'Guanosine', 'Humans', 'Mice', 'Models, Molecular', 'Molecular Sequence Data', 'NIH 3T3 Cells', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Conformation', 'RNA... | 23,431,134 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G01.154'], ['C04.697.098.500', 'C23.550.727.098.500'], ['G02.111.570.580'], ['D12.776.157.725.750.374', 'D12.776.835.725.868.500.750'], ['D03.633.100.759.590.454', 'D13.570.583.454', 'D13.570.800.453'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ultra-trace recognition and removal of toxic chromium (VI) ions from water using visual mesocaptor. | The key to designing optical mesocaptors is to construct a chromogenic receptor, namely, diphenylcarbazide (DPC), as a nanoscale platform scavenger with different functional characteristics, such as density, accessibility, and intrinsic mobility. Engineering of optical captors allows facile and reliable signaling in co... | ['Adsorption', 'Aluminum Silicates', 'Chromium', 'Diphenylcarbazide', 'Indicators and Reagents', 'Water Pollutants, Chemical'] | 23,195,598 | [['G01.030', 'G02.020'], ['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D02.845.250'], ['D27.720.470.410'], ['D27.888.284.903.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Validity of deterministic record linkage using multiple indirect personal identifiers: linking a large registry to claims data. | BACKGROUND: Linking patient registries with administrative databases can enhance the utility of the databases for epidemiological and comparative effectiveness research. However, registries often lack direct personal identifiers, and the validity of record linkage using multiple indirect personal identifiers is not wel... | ['Female', 'Hospitalization', 'Humans', 'Information Storage and Retrieval', 'Inpatients', 'Insurance Claim Reporting', 'Male', 'Medical Record Linkage', 'Medical Records Systems, Computerized', 'Medicare', 'Records', 'Registries', 'Reproducibility of Results', 'Sensitivity and Specificity', 'United States'] | 24,755,909 | [['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['M01.643.470'], ['N03.219.521.576.210'], ['E05.318.308.940.968.500', 'N04.452.859.564.550', 'N05.715.360.300.715.500.500', 'N06.850.520.308.940.968.500'], ['E05.318.308.940.968.625', 'L01.313.500.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
A genetic analysis of the Epworth Sleepiness Scale in 1560 World War II male veteran twins in the NAS-NRC Twin Registry. | Responses to the eight-item Epworth Sleepiness Scale (ESS) obtained from 1560 World War II male veteran twin pairs [818 monozygotic (MZ), 742 dizygotic (DZ)] were analysed to determine the extent to which genetic influences are involved in self-reported daytime sleepiness in the elderly. Average ESS score (+/- SD) in t... | ['Aged', 'Aged, 80 and over', 'Aging', 'Human Activities', 'Humans', 'Likelihood Functions', 'Male', 'Registries', 'Sleep', 'Twins', 'Twins, Dizygotic', 'Twins, Monozygotic', 'Veterans', 'Wakefulness'] | 11,285,055 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['I03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.400'], ['E05.318.308.970', 'N0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Pharmacokinetics of angiotensin converting enzyme inhibition in tissues following oral lisinopril: studies in the rat using quantitative radioinhibitor binding. | 1. The pharmacokinetics of angiotensin converting enzyme (ACE) inhibition in plasma and tissues were measured in the rat following 10 mg/kg lisinopril given by oral gavage. 2. Specific binding of 125I-351A to ACE was measured in plasma, and homogenates of lung, aorta, kidney, testis, epididymis and brain, and used as a... | ['Administration, Oral', 'Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Enalapril', 'Iodine Radioisotopes', 'Lisinopril', 'Male', 'Radioligand Assay', 'Rats', 'Rats, Inbred Strains'] | 2,822,313 | [['E02.319.267.100'], ['D27.505.519.389.745.085'], ['B01.050'], ['D12.644.456.345.360'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D12.644.456.345.600'], ['E01.370.225.985', 'E01.370.374.650', 'E01.370.384.720', 'E05.200.985'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.52... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PI3Kã within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance. | Obesity is associated with a chronic low-grade inflammation, and specific antiinflammatory interventions may be beneficial for the treatment of type 2 diabetes and other obesity-related diseases. The lipid kinase PI3Kã is a central proinflammatory signal transducer that plays a major role in leukocyte chemotaxis, mast ... | ['Adipose Tissue, White', 'Animals', 'Class Ib Phosphatidylinositol 3-Kinase', 'Diet, High-Fat', 'Fatty Liver', 'Inflammation', 'Insulin Resistance', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Models, Biological', 'Obesity', 'Phenotype', 'RNA, Messenger', 'Signal Transduction', 'Sterol Esterase', 'Thermog... | 21,949,398 | [['A10.165.114.830'], ['B01.050'], ['D08.811.913.696.620.500.100.100.200', 'D08.811.913.696.620.500.200.100.200', 'D12.776.476.162.200'], ['G07.203.650.240.267'], ['C06.552.241'], ['C23.550.470'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420'... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative diuretic activity of delta9-tetrahydrocannabinol, cannabidiol, cannabinol and hydrochlorothiazide in the rat. | Orally administered delta9-tetrahydrocannabinol (THC) produced a dose-dependent increase in urine output in hydrated rats similar in mg/kg potency and magnitude of effect to hydrochlorothiazide (HCT). Whereas HCT promoted marked excretion of Na+, K+ and Cl- and an increase in the urinary Na+/K+ at all diuretic doses (1... | ['Administration, Oral', 'Animals', 'Cannabidiol', 'Cannabinoids', 'Cannabinol', 'Chlorides', 'Diuretics', 'Dronabinol', 'Hydrochlorothiazide', 'Male', 'Potassium', 'Rats', 'Sodium', 'Time Factors'] | 849,066 | [['E02.319.267.100'], ['B01.050'], ['D02.455.849.090.100'], ['D02.455.849.090'], ['D02.455.849.090.110'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D27.505.696.560.500'], ['D02.455.849.090.810'], ['D02.886.590.700.135.261.476', 'D02.886.655.500.261.476', 'D03.633.100.174.261.476'], ['D01.268.549.550', 'D01.268.557.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effect of chemotherapy treatment on hemostasis of patients with lung cancer]. | Chemotherapy is known to raise the risk of developing thrombotic complications. The aim of our work is to study the system of hemostasis in patients with the lung cancer under chemotherapy treatment. 61 patients were examined (40 men, 21 women) between the ages of 32 and 75 years (the principal group). Chemotherapy was... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Blood Platelets', 'Female', 'Hemostasis', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging'] | 18,830,029 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['A11.118.188', 'A15.145.229.188'], ['G09.188.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E01.789.625']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of 20 years of environmental monitoring data around Swedish nuclear installations. | Twenty years of environmental monitoring data around the Swedish nuclear power plants and the Studsvik research facilities have been evaluated. In the marine environment, Fucus vesiculosus generally has high activity concentrations and the presence of a large variety of radionuclides in comparison with other bioindicat... | ['Animals', 'Bivalvia', 'Body Burden', 'Cobalt Radioisotopes', 'Environmental Health', 'Europium', 'Fishes', 'Geologic Sediments', 'Humans', 'Models, Theoretical', 'Nuclear Reactors', 'Radiation Monitoring', 'Radioactive Pollutants', 'Radioisotopes', 'Seawater', 'Silver', 'Sweden'] | 12,363,266 | [['B01.050'], ['B01.050.500.644.080'], ['E05.799.638.231', 'N06.850.460.200'], ['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['H02.229'], ['D01.268.558.362.468', 'D01.552.550.399.468'], ['B01.050.150.900.493'], ['G01.311.330', 'G16.500.320'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Linking research to global health equity: the contribution of product development partnerships to access to medicines and research capacity building. | Certain product development partnerships (PDPs) recognize that to promote the reduction of global health disparities they must create access to their products and strengthen research capacity in developing countries. We evaluated the contribution of 3 PDPs--Medicines for Malaria Venture, Drugs for Neglected Diseases In... | ['Capacity Building', 'Developing Countries', 'Global Health', 'Health Services Accessibility', 'Healthcare Disparities', 'Humans', 'Malaria', 'Neglected Diseases', 'Pharmaceutical Preparations', 'Public-Private Sector Partnerships', 'Research'] | 24,028,246 | [['N02.138', 'N04.452.105'], ['I01.615.500.300'], ['H02.403.371', 'N01.400.337'], ['N04.590.374.350', 'N05.300.430'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530', 'C01.920.875'], ['C23.550.291.890'], ['D26'], ['J01.219.843', 'N03.540.706'], ['H01.770.644']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Deficiency of membrane-bound dipeptidyl aminopeptidase IV in a certain rat strain. | The activity of membrane-bound dipeptidyl aminopeptidase IV (EC 3.4.14.5) was found to be markedly reduced in the Fischer 344 rat strain compared with that in the Wistar strain. Analysis of membrane proteins by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Ouchterlony immunodiffusion revealed the specif... | ['Animals', 'Cell Membrane', 'Dipeptidyl Peptidase 4', 'Dipeptidyl-Peptidases and Tripeptidyl-Peptidases', 'Electrophoresis, Polyacrylamide Gel', 'Immunodiffusion', 'Kidney', 'Male', 'Molecular Weight', 'Rats', 'Rats, Inbred F344', 'Rats, Inbred Strains', 'Tissue Distribution'] | 2,883,023 | [['B01.050'], ['A11.284.149'], ['D08.811.277.656.350.350.126', 'D08.811.277.656.959.250', 'D23.050.301.264.894.160', 'D23.101.100.894.160'], ['D08.811.277.656.350.350'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are serum anticonvulsant levels in people with epilepsy appropriately monitored? | The medical care of people with epilepsy has often been described as being poor, although objective markers for the quality of epilepsy care are lacking. This paper describes the results of using a simple quality marker, appropriate measuring of serum anticonvulsant levels, in assessing the quality of epilepsy care. Th... | ['Anticonvulsants', 'Drug Monitoring', 'Epilepsy', 'Humans', 'Logistic Models', 'Phenytoin', 'Valproic Acid'] | 11,555,091 | [['D27.505.954.427.080'], ['E01.370.520.200'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06.850.520.830.500.525'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Attentional deficits in stroke patients: a visual dual task experiment. | OBJECTIVE: (1) To compare the performance of subjects who have suffered a single lateralized cortical, ischemic stroke versus controls on measures of attention including a computerized dual visual attentional task to determine if this task is more sensitive for detecting the presence of subtle hemi-inattention compared... | ['Aged', 'Aged, 80 and over', 'Attention Deficit Disorder with Hyperactivity', 'Cerebrovascular Disorders', 'Computers', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychomotor Performance', 'Time Factors'] | 9,014,950 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.625.094.150'], ['C10.228.140.300', 'C14.907.253'], ['L01.224.230.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['G01.910.857']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Cochlear dysfunction in IDDM patients with subclinical peripheral neuropathy. | OBJECTIVE: To investigate the function of the auditory pathway from the cochlea to the auditory cortex in subjects with IDDM.RESEARCH DESIGN AND METHODS: Brain stem, middle-, and long-latency auditory-evoked responses and evoked otoacoustic emissions were measured in 48 normally hearing IDDM patients and in age- and se... | ['Adult', 'Auditory Cortex', 'Cochlea', 'Diabetes Mellitus, Type 1', 'Diabetic Neuropathies', 'Electrophysiology', 'Evoked Potentials, Auditory', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Male', 'Reference Values'] | 9,135,949 | [['M01.060.116'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['A09.246.300.246'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C10.668.829.300', 'C19.246.099.937'], ['H01.158.344.528', 'H01.158.782.236'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['G... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Detection of viruses and virus-like particles in four species of wild and farmed bivalve molluscs in Alaska, U.S.A., from 1987 to 2009. | The U.S. Alaska Department of Fish and Game has regulatory oversight of the mariculture industry that is partially administered through a statewide shellfish health policy. Possession and transport of bivalve molluscs require development of indigenous pathogen histories from diagnostic examinations of wild and farmed p... | ['Alaska', 'Animals', 'Bivalvia', 'Cell Line', 'Fishes', 'Time Factors', 'Virus Diseases'] | 20,183,960 | [['Z01.107.567.875.580.100'], ['B01.050'], ['B01.050.500.644.080'], ['A11.251.210'], ['B01.050.150.900.493'], ['G01.910.857'], ['C01.925']] | ['Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Phytoestrogen coumestrol attenuates brain mitochondrial dysfunction and long-term cognitive deficits following neonatal hypoxia-ischemia. | INTRODUCTION: Neonatal Hypoxia-Ischemia (HI) is a major cause of morbidity and mortality, and is frequently associated with short and long-term neurologic and cognitive impairments. The HI injury causes mitochondrial damage leading to increased production of reactive oxygen species (ROS). Phytoestrogens are non-steroid... | ['Animals', 'Brain', 'Cognition', 'Cognitive Dysfunction', 'Coumestrol', 'Hypoxia-Ischemia, Brain', 'Male', 'Maze Learning', 'Mitochondria', 'Neuroprotective Agents', 'Phytoestrogens', 'Rats', 'Rats, Wistar', 'Reactive Oxygen Species'] | 31,693,927 | [['B01.050'], ['A08.186.211'], ['F02.463.188'], ['F03.615.250.700'], ['D03.383.663.283.266.450.400.187', 'D03.383.663.283.446.350', 'D03.633.100.150.266.450.400.187', 'D03.633.100.150.446.350'], ['C10.228.140.300.150.716', 'C10.228.140.624.500', 'C14.907.253.092.716', 'C23.888.852.079.797.500'], ['F02.463.425.874.500']... | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation. | Mitosis is commonly thought to be associated with reduced cap-dependent protein translation. Here we show an alternative control mechanism for maintaining cap-dependent translation during mitosis revealed by a viral oncoprotein, Merkel cell polyomavirus small T (MCV sT). We find MCV sT to be a promiscuous E3 ligase inh... | ['Adaptor Proteins, Signal Transducing', 'Antigens, Polyomavirus Transforming', 'CDC2 Protein Kinase', 'Cell Cycle Proteins', 'Cell Proliferation', 'Cyclin-Dependent Kinases', 'HEK293 Cells', 'HeLa Cells', 'Humans', 'Interphase', 'Mitosis', 'Neoplasms', 'Nocodazole', 'Phosphoproteins', 'Phosphorylation', 'Protein Bindi... | 25,883,264 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.776.624.664.520.090', 'D12.776.964.700.090', 'D23.050.285.062.090', 'D23.050.327.062.090'], ['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are thyroid nodules with spongiform morphology always benign? | OBJECTIVE: Fine needle aspiration (FNA) biopsy for evaluation of spongiform nodules ?20 mm or observation without FNA was recommended by American Thyroid Association. However, this was a weak recommendation supported by moderate quality evidence. We aimed to assess malignancy risk in spongiform nodules.METHODS: From Ja... | ['Biopsy, Fine-Needle', 'Diagnosis, Differential', 'Elasticity Imaging Techniques', 'Female', 'Humans', 'Image-Guided Biopsy', 'Male', 'Middle Aged', 'Neoplasms', 'Thyroid Gland', 'Thyroid Neoplasms', 'Thyroid Nodule', 'Ultrasonography'] | 30,244,500 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.171'], ['E01.370.350.850.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgia. | OBJECTIVE: To compare the momentary association between salivary cortisol levels and pain, fatigue, and stress symptoms in patients with fibromyalgia (FM), and to compare diurnal cycles of cortisol secretion in patients with FM and healthy control subjects in a naturalistic environment.METHODS: Twenty-eight patients wi... | ['Adult', 'Circadian Rhythm', 'Fatigue', 'Female', 'Fibromyalgia', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Male', 'Pain', 'Pituitary-Adrenal System', 'Saliva', 'Stress, Psychological'] | 16,258,904 | [['M01.060.116'], ['G07.180.562.190'], ['C23.888.369'], ['C05.651.324', 'C05.799.321', 'C10.668.491.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Use of video-thoracoscopy for diagnostic and small surgical procedures in the chest]. | The report introduces videothoracoscopy as a new diagnostic and therapeutical method in chest surgery. The main indications for thoracoscopic procedures were described. Also, 37 videothoracoscopic procedures performed on 35 patients were presented. In 5 cases procedure was therapeutical, in the rest of them diagnostic.... | ['Biopsy', 'Humans', 'Lung Diseases', 'Lung Neoplasms', 'Thoracic Diseases', 'Thoracoscopy', 'Video Recording'] | 7,633,371 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C08.846'], ['E01.370.388.250.840', 'E04.502.250.840', 'E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Selenium bioaccumulation and body condition in shorebirds and terns breeding in San Francisco Bay, California, USA. | The present study evaluated Se bioaccumulation in four waterbird species (n=206 birds) that breed within San Francisco Bay, California, U.S.A.: American avocets (Recurvirostra americana), black-necked stilts (Himantopus mexicanus), Forster's terns (Sterna forsteri), and Caspian terns (Hydroprogne caspia). Selenium conc... | ['Animals', 'Breeding', 'Charadriiformes', 'Environmental Monitoring', 'Environmental Pollutants', 'Female', 'Liver', 'Male', 'Reproducibility of Results', 'San Francisco', 'Selenium', 'Species Specificity'] | 19,459,720 | [['B01.050'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.248.150'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['A03.620'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['Z01.107.567.875.580.200.700', 'Z01.107.567.875.760.200.700', 'Z01.433.875'], ['D01.268.185.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The enterohepatic physiology of 24,25-dihydroxyvitamin D3. | Products of intravenously administered [3H]24,25-dihydroxyvitamin D3 are excreted in the bile of normocalcemic, vitamin D-replete rats. Within 3 and 24 hr, 7.3% +/- 1.4 and 18.5% +/- 1.4 (mean +/- S.D.) of the administered dose appears in the bile. Three hours after the instillation of the biliary products of [3H]24,25... | ['24,25-Dihydroxyvitamin D 3', 'Animals', 'Chickens', 'Dihydroxycholecalciferols', 'Enterohepatic Circulation', 'Hydroxycholecalciferols', 'Male', 'Rats'] | 6,967,504 | [['D04.210.500.247.222.159.478.387.400', 'D04.210.500.247.808.146.478.387.400', 'D04.210.500.812.768.196.478.387.400', 'D10.570.938.146.478.387.400'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D04.210.500.247.222.159.478.387', 'D04.210.500.247.808.146.478.387', 'D04.210.500.812.768.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delineation of structural domains in eukaryotic 5S rRNA with a rhodium probe. | The three-dimensional folding of Xenopus oocyte 5S rRNA has been examined using the coordination complex Rh(phen)2phi3+ (phen = phenanthroline; phi = phenanthrenequinone diimine) as a structural probe. Rh(phen)2phi3+ binds neither double-helical RNA nor unstructured single-stranded regions of RNA. Instead, the complex ... | ['Animals', 'Base Sequence', 'Binding Sites', 'Intercalating Agents', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Nucleic Acid Conformation', 'Oocytes', 'Organometallic Compounds', 'Phenanthrenes', 'Phenanthrolines', 'Photochemistry', 'RNA, Ribosomal, 5S', 'Rhodium', 'Xenopus'] | 1,554,733 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D27.720.470.410.360'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['G02.111.570.820.486', 'G05.360.580'], ['A05.360.490.690.680', 'A11.497.497.600'], ['D02.691'], ['D02.455.426.559.847.723', 'D04.615.723'], ['D03.633.300.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Application of the 2006 WHO growth standard from birth to 4 years to Pacific Island children. | BACKGROUND: Pacific adults and children have very high rates of obesity.OBJECTIVE: Body size at birth, 2- and 4 years for the whole cohort, compliant (not smoking and breastfed) and non-compliant children was compared to the 2006 World Health Organization (WHO) growth standard using z-scores.DESIGN: Longitudinal data (... | ['Age Factors', 'Body Height', 'Body Mass Index', 'Body Weight', 'Child, Preschool', 'Cohort Studies', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Obesity', 'Pacific Islands', 'Reference Standards', 'World Health Organization'] | 17,968,380 | [['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Acacetin inhibits neuronal cell death induced by 6-hydroxydopamine in cellular Parkinson's disease model. | Acacetin (5,7-dihydroxy-4'-methoxyflavone), a flavonoid compound isolated from Flos Chrysanthemi Indici, chrysanthemum, safflower, and Calamintha and Linaria species has been shown to have anti-cancer activity, indicating its potential clinical value in cancer treatment. In this study, we sought to study the potentials... | ['Cell Death', 'Cell Line, Tumor', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Flavones', 'Humans', 'Membrane Potential, Mitochondrial', 'Molecular Structure', 'Neurons', 'Oxidopamine', 'Parkinson Disease', 'Reactive Oxygen Species', 'Structure-Activity Relationship'] | 29,089,232 | [['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['D03.383.663.283.266.450.260', 'D03.633.100.150.266.450.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.295.770.500', 'G04.580.550', 'G07.265.675.550'], ['G02.111.570', 'G02.466'], ['A08.675', 'A11.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Barrier functionality and transport machineries of human ECV304 cells. | BACKGROUND: The lack of a brain-derived endothelial cell-based model has led researchers to exploit non-brain endothelial/epithelial cells as in vitro models for blood-brain barrier (BBB) investigations. Of these, the endothelial-like human ECV304 cell line was initially characterized as endothelial cells and has been ... | ['Blood-Brain Barrier', 'Butyric Acid', 'Cell Line, Tumor', 'Cell Membrane Permeability', 'Dexamethasone', 'Electric Impedance', 'Epithelial Cells', 'Gene Expression Regulation', 'Humans', 'Membrane Transport Proteins', 'Models, Biological', 'Tight Junctions', 'gamma-Linolenic Acid'] | 20,037,486 | [['A07.035', 'A08.186.211.035'], ['D02.241.081.114.750', 'D10.251.400.143.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G03.143.335', 'G04.175'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G01.358.500.249.277.350'], ['A11.436'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.1... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparing the next generation of scientists in translation research. | AIM: Four questions about translation research are considered in this article. (1) Why should there be concern about preparing nurse scientists for translation research? (2) Are current research-intensive doctoral programs in nursing preparing graduates for translation research? (3) Should targeted efforts be made to s... | ['Curriculum', 'Diffusion of Innovation', 'Education, Nursing, Graduate', 'Evidence-Based Medicine', 'Forecasting', 'Health Services Needs and Demand', 'Humans', 'Information Dissemination', 'Internet', 'Nursing Research', 'Organizational Objectives', 'Outcome Assessment, Health Care', 'Program Evaluation', 'Research P... | 17,129,339 | [['I02.158'], ['L01.143.320'], ['I02.358.337.450', 'I02.358.462.565'], ['H02.249.750', 'H02.403.200.400'], ['I01.320'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['L01.224.230.110.500'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613'], ['N04.452.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Variability in photobleaching yields and their related impacts on optical conditions in subtropical lakes. | Changes in the concentration and spectral absorption of chromophoric dissolved organic matter (CDOM) may strongly condition the optical properties of tropical and subtropical water bodies. We examined the spatial distribution of CDOM-related absorption, spectral slope and vertical attenuation of solar radiation in two ... | ['Absorption', 'Ecosystem', 'Environmental Monitoring', 'Fresh Water', 'Organic Chemicals', 'Photobleaching', 'Photolysis', 'Solar Energy', 'Sunlight', 'Wetlands'] | 19,303,317 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.280', 'N06.230.232'], ['D02'], ['G02.740.680'], ['G02.740.685'], ['G01.750.897', 'N06.230.132.644.500'], ['G01.358.500.505.650.836', 'G01.750.250.650.836', ... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Role models play the greatest role - a qualitative study on reasons for choosing postgraduate training at a university hospital. | OBJECTIVE: Why physicians choose a certain specialty at a university hospital for their postgraduate training is incompletely understood. Our aim was to identify factors that led physicians from different generations to opt for postgraduate training in a specialty with high or low patient contact at a university hospit... | ['Adult', 'Career Choice', 'Education, Medical, Graduate', 'Female', 'Germany', 'Hospitals, University', 'Humans', 'Internal Medicine', 'Internship and Residency', 'Male', 'Medical Laboratory Personnel', 'Medical Staff, Hospital', 'Medicine', 'Models, Psychological', "Physician's Role"] | 25,489,345 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['I02.358.337.350', 'I02.358.399.350'], ['Z01.542.315'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['M01.526.485.510', 'M01.526.502.500', 'N02.360.510'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Development of diamond-based X-ray detection for high-flux beamline diagnostics. | High-quality single-crystal and polycrystalline chemical-vapor-deposition diamond detectors with platinum contacts have been tested at the white-beam X28C beamline at the National Synchrotron Light Source under high-flux conditions. The voltage dependence of these devices has been measured under both DC and pulsed-bias... | ['Calibration', 'Diamond', 'Equipment Design', 'Radiometry', 'Synchrotrons', 'X-Rays'] | 20,975,215 | [['E05.978.155'], ['D01.268.150.200'], ['E05.320'], ['E05.799'], ['E07.710.680.700'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Possible conformation of amphotericin B dimer in membrane-bound assembly as deduced from solid-state NMR. | Aiming for structural analysis of amphotericin B (AmB) ion-channel assemblies in membrane, a covalent dimer was synthesized between (13)C-labled AmB methyl ester and (19)F-labled AmB. The dimer showed slightly weaker but significant biological activities against fungi and red blood cells compared with those of monomeri... | ['Amphotericin B', 'Antifungal Agents', 'Aspergillosis', 'Aspergillus niger', 'Dimerization', 'Erythrocytes', 'Hemolysis', 'Humans', 'Lipid Bilayers', 'Magnetic Resonance Spectroscopy', 'Molecular Conformation'] | 22,959,766 | [['D02.540.576.500.500'], ['D27.505.954.122.136'], ['C01.150.703.080'], ['B01.300.381.081.450'], ['G02.206', 'G03.230'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.570.510', 'J01.637.087.500.510'], ['E05.196.867.519'], ['G02.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
CT in idiopathic pyogenic myositis of the iliopsoas muscle. A report of 2 cases. | Pyogenic myositis of the iliopsoas muscle may occur as a primary clinical entity of an idiopathic nature, or more commonly secondarily to an adjacent disease process. We report 2 cases of idiopathic pyogenic infection caused by Staphylococcus aureus. This disease entity is rare in temperate climates. CT combined with c... | ['Abscess', 'Adolescent', 'Adult', 'Anti-Bacterial Agents', 'Humans', 'Male', 'Muscles', 'Myositis', 'Retroperitoneal Space', 'Staphylococcal Infections', 'Tomography, X-Ray Computed'] | 6,840,097 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633', 'A10.690'], ['C05.651.594', 'C10.668.491.562'], ['A01.923.047.025.750'], ['C01.150.252.410.868'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.3... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of fulvestrant 750mg in premenopausal women with oestrogen-receptor-positive primary breast cancer. | Fulvestrant (Faslodex) is a pure anti-oestrogen that reduces markers of hormone sensitivity and proliferation in postmenopausal women with oestrogen-receptor (ER)-positive breast cancer. This randomised trial compared the effects on the tumours of a single dose of 750mg fulvestrant to those of daily tamoxifen (20mg) ta... | ['Adult', 'Antineoplastic Agents, Hormonal', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Estradiol', 'Female', 'Fulvestrant', 'Humans', 'Injections, Intramuscular', 'Ki-67 Antigen', 'Middle Aged', 'Neoplasms, Hormone-Dependent', 'Premenopause', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Tamoxifen', 'Treatment Out... | 18,083,023 | [['M01.060.116'], ['D27.505.954.248.169'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D04.210.500.365.415.248.660', 'D06.472.334.851.437.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['D12.776.660.625.500', 'D23.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
TT virus levels in the plasma of infected individuals with different hepatic and extrahepatic pathology. | TT virus (TTV) infection is extremely widespread in the general population. A sensitive real-time PCR assay was developed that quantitated accurately the most prevalent TTV genotypes in Italy. When used to test 217 individuals for TTV viraemia, the overall prevalence was 94%. Viraemia levels varied widely amongst indiv... | ['Adolescent', 'Adult', 'Base Sequence', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'DNA Primers', 'DNA Virus Infections', 'Hemophilia A', 'Hepatitis, Viral, Human', 'Humans', 'Liver Diseases', 'Middle Aged', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Torque teno virus', 'Viral Load', 'Viremi... | 11,170,056 | [['M01.060.057'], ['M01.060.116'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['C01.925.256'], ['C15.378.100.100.500', 'C15.378... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Experimental infections of Eimeria wapiti and E. zuernii-like oocysts in Rocky Mountain elk (Cervus elaphus) calves. | Four Rocky Mountain elk (Cervus elaphus) 10 to 14 wk of age each were inoculated orally with a mixture of 50,000 sporulated oocysts of an Eimeria zuernii-like apicomplexan (70%) and E. wapiti (30%). Maximum numbers of oocysts per gram of feces (OPG) in each elk ranged from 985 to 15,517, but all calves remained healthy... | ['Animals', 'Coccidiosis', 'Deer', 'Eimeria', 'Feces', 'Female', 'Male', 'Parasite Egg Count'] | 7,933,299 | [['B01.050'], ['C01.610.752.250'], ['B01.050.150.900.649.313.500.380.373'], ['B01.043.075.189.250.250.250'], ['A12.459'], ['E01.370.225.932.600', 'E05.200.932.600']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The physiology of world-class sprint skiers. | The present study investigated the physiological characteristics of eight world-class (WC) and eight national-class (NC) Norwegian sprint cross country skiers. To measure the physiological response and treadmill performance, the skiers performed a submaximal test, a peak aerobic capacity (VO2peak) test, and a peak trea... | ['Adult', 'Anthropometry', 'Athletes', 'Athletic Performance', 'Exercise Test', 'Humans', 'Male', 'Norway', 'Oxygen Consumption', 'Skiing', 'Young Adult'] | 20,500,558 | [['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.072'], ['I03.450.642.845.054'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.374'], ['G03.680'], ['I03.450.642.845.787.500'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation. | The Dnmt3a DNA methyltransferase contains in its N-terminal part a PWWP domain that is involved in chromatin targeting. Here, we have investigated the interaction of the PWWP domain with modified histone tails using peptide arrays and show that it specifically recognizes the histone 3 lysine 36 trimethylation mark. H3K... | ['Animals', 'Cell Line', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA Methylation', 'Histones', 'Humans', 'Lysine', 'Methylation', 'Mice', 'Protein Array Analysis', 'Protein Binding', 'Protein Structure, Tertiary', 'Transfection'] | 20,547,484 | [['B01.050'], ['A11.251.210'], ['D08.811.913.555.500.350.100.500'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['G02.1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of the modified Stainsby procedure in correcting severe claw toe deformity in the rheumatoid foot: a retrospective review. | INTRODUCTION: In claw toe deformity, the plantar plate of the metarsophalangeal joint becomes displaced onto the dorsal aspect of the metatarsal head. The Stainsby procedure replaces the displaced plantar plate to its correct position beneath the metatarsal head.OBJECTIVE: In this study we assess the efficacy of a modi... | ['Aged', 'Arthritis, Rheumatoid', 'Bone Wires', 'Female', 'Foot Deformities, Acquired', 'Humans', 'Male', 'Middle Aged', 'Orthopedic Procedures', 'Patient Satisfaction', 'Retrospective Studies', 'Toes', 'Treatment Outcome'] | 20,307,460 | [['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['C05.330.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.718', 'E04.555'], ['F01.100.150.750.625', 'F01.145.488.887.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does the number of hypopnoeas influence therapy in patients with obstructive sleep apnoea? | The definition of hypopnoea varies widely between sleep laboratories. This study sought to evaluate the impact upon therapeutic decision of the most commonly used one, which defines hypopnoea as a reduction in airflow of 50% (or more) accompanied by a decreased blood oxygen saturation of 4% (or more) (Agency for Health... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anthropometry', 'Body Mass Index', 'Carbon Dioxide', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oxygen', 'Partial Pressure', 'Polysomnography', 'Sleep Apnea Syndromes', 'Spirometry'] | 9,893,771 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Open reduction and internal fixation of acute mandibular fractures in adults. | The mandible is often fractured during maxillofacial trauma because of its prominence within the facial skeleton and the fact that it is a favorite target in interpersonal violence. Treatment of mandibular fractures has made significant advances over the years due to the study of biomechanical principles, advancements ... | ['Adult', 'Bone Plates', 'Fracture Fixation, Internal', 'Humans', 'Jaw Fixation Techniques', 'Mandibular Condyle', 'Mandibular Fractures', 'Patient Care Planning'] | 10,371,890 | [['M01.060.116'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.545.440', 'E06.645.440'], ['A02.835.232.781.324.502.632.600', 'A14.521.632.600'], ['C10.900.300.284.500.400.255', 'C26.404.750.467.441', 'C26.915.300.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The circle of Willis predicts the antihypertensive effects of carotid artery stenting. | OBJECTIVE Carotid artery stenting (CAS) has antihypertensive effects, but the durability and degree of this response remain variable. The authors propose that this clinical variability is a function of the presence or absence of a complete circle of Willis (COW). Incomplete COWs perfuse through a higher-resistance pial... | ['Blood Pressure', 'Carotid Stenosis', 'Case-Control Studies', 'Circle of Willis', 'Cohort Studies', 'Databases, Factual', 'Female', 'Humans', 'Hypertension', 'Male', 'Predictive Value of Tests'] | 28,366,069 | [['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A07.015.114.228.351'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['L01.313.500.750.300... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Cardioinhibitory-vasodepressor response to head-up tilt without hypoxaemia or myocardial ischaemia. | We evaluated whether hypoxaemia and/or myocardial ischaemia are of importance for development of the bradycardic hypotensive phase (cardioinhibitory-vasodepressor syncope) of central hypovolaemia. Arterial blood gas variables and a twelve-lead electrocardiogram (ECG) were followed during head-up tilt in seven men. Duri... | ['Adult', 'Blood Gas Analysis', 'Blood Pressure', 'Blood Vessels', 'Cardiac Output', 'Cardiography, Impedance', 'Central Venous Pressure', 'Electrocardiography', 'Head', 'Heart', 'Heart Rate', 'Humans', 'Hypoxia', 'Male', 'Myocardial Ischemia', 'Posture', 'Vascular Resistance'] | 8,519,164 | [['M01.060.116'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E01.370.370.380.160', 'E01.370.370.610.610.200'], ['G09.330.380.076.732.336'], ['E01.370.370.380.240', 'E01.370.405.240'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cytogenetic clonal evolution alone in CML relapse post-transplantation does not adversely affect response to imatinib mesylate treatment. | Good prognosis after imatinib mesylate treatment has been reported if cytogenetic clonal evolution (CE) is the only criterion of accelerated phase (AP) chronic myelogenous leukemia (CML). To evaluate the impact of CE upon imatinib treatment in post-transplant settings, responses and toxicities in the relapsed AP-CE wer... | ['Adult', 'Antineoplastic Agents', 'Benzamides', 'Clone Cells', 'Combined Modality Therapy', 'Female', 'Graft vs Host Disease', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Imatinib Mesylate', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Middle Aged', 'Neoplasm, Residual', 'Piperazines', 'Pyrim... | 14,628,081 | [['M01.060.116'], ['D27.505.954.248'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['A11.251.353'], ['E02.186'], ['C20.452'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.277.456', 'D02.241.223.100.100.435', 'D02.455.426.559.38... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Glycothiohexides, novel antibiotics produced by "Sebekia" sp. LL-14E605. I. Taxonomy, fermentation and biological evaluation. | The new glycothiohexide antibiotics, which are related to nosiheptide, were identified in fermentations of an actinomycete belonging to the genus "Sebekia". Strain LL-14E605 was classified as a "Sebekia" based on the presence of both mesodiaminopimelic acid and madurose in the cell wall and the presence of pseudosporan... | ['Actinomycetales', 'Anti-Bacterial Agents', 'Fermentation', 'Gram-Positive Bacteria', 'Microbial Sensitivity Tests', 'Peptides'] | 7,928,675 | [['B03.510.024.049'], ['D27.505.954.122.085'], ['G02.111.158.249', 'G03.191.249'], ['B03.510'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D12.644']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dual role of the tyrosine kinase GTK and the adaptor protein SHB in beta-cell growth: enhanced beta-cell replication after 60% pancreatectomy and increased sensitivity to streptozotocin. | Transgenic CBA mice expressing either the tyrosine kinase GTK (gut tyrosine kinase) or the adaptor protein SHB (Src homology 2 protein of beta-cells) under the control of the rat insulin promoter exhibited an increased beta-cell mass, but also elevated cytokine-induced islet cell death compared with control mice. To fu... | ['Animals', 'Cell Death', 'Cell Division', 'Female', 'Glucose Tolerance Test', 'Islets of Langerhans', 'Male', 'Mice', 'Mice, Inbred CBA', 'Mice, Transgenic', 'Pancreatectomy', 'Protein-Tyrosine Kinases', 'Proto-Oncogene Proteins', 'Streptozocin'] | 11,786,382 | [['B01.050'], ['G04.146'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['A03.734.414', 'A06.300.414'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.440', 'B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis. | Caspase 8 plays an essential role in the execution of death receptor-mediated apoptosis. To determine the localization of endogenous caspase 8, we used a panel of subunit-specific anti-caspase 8 monoclonal antibodies in confocal immunofluorescence microscopy. In the human breast carcinoma cell line MCF7, caspase 8 pred... | ['Actins', 'Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Apoptosis', 'Biological Transport', 'Breast Neoplasms', 'Carcinoma', 'Caspase 8', 'Caspase 9', 'Caspases', 'Cytoplasm', 'Enzyme Precursors', 'Fibroblasts', 'Gelsolin', 'Humans', 'Intermediate Filament Proteins', 'Keratins', 'Lamin Type B', 'Lamins'... | 10,891,503 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.146.954.035'], ['G03.143'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['D08... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Temporal selectivity in the central auditory system of the leopard frog. | Amplitude modulation is a predominant temporal feature in many vocal signals. The leopard frog, Rana pipiens, has a class of neurons in the central auditory system that respond selectively to particular rates of amplitude modulation; these neurons can be characterized by a temporal tuning curve. Such selectivity is abs... | ['Animal Communication', 'Animals', 'Auditory Pathways', 'Auditory Perception', 'Brain', 'Rana pipiens', 'Time Factors'] | 6,600,522 | [['F01.145.113.055'], ['B01.050'], ['A08.612.220.110'], ['F02.463.593.071', 'G07.888.125'], ['A08.186.211'], ['B01.050.150.900.090.180.708.310'], ['G01.910.857']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A study of age-related variables among physically abused children. | One of every five substantiated cases of child abuse and over 50 percent of child-abuse-related deaths are the result of physical injury. The charts of 266 children, newborn to seventeen years of age, seen at Texas Children's Hospital during a two-year period were reviewed. Each child was assigned to one of four age-gr... | ['Adolescent', 'Age Factors', 'Child', 'Child Abuse', 'Child, Preschool', 'Craniocerebral Trauma', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Retrospective Studies', 'Texas', 'Trauma Severity Indices', 'Wounds and Injuries'] | 8,893,982 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.060.406.448'], ['C10.900.300', 'C26.915.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Gabor fusion technique in a Talbot bands optical coherence tomography system. | In this paper we show how to advantageously combine two effects to enhance the sensitivity with depth in Fourier domain (FD) optical coherence tomography (OCT): Talbot bands (TB) and Gabor-based fusion (GF) technique. TB operation is achieved by routing the two beams, from the object arm and from the reference arm in t... | ['Algorithms', 'Equipment Design', 'Equipment Failure Analysis', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Interferometry', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Subtraction Technique', 'Tomography, Optical Coherence'] | 22,418,344 | [['G17.035', 'L01.224.050'], ['E05.320'], ['E05.325.192'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E05.490'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Perspectives on nursing care of Chinese Americans. | Chinese population growth in the United States is expected to accelerate more rapidly than that of any other Asian group in the coming decades. As a result, nurses will be encountering members of this diverse and rich cultural group more frequently. A better understanding of the cultural beliefs, customs, and health ca... | ['Attitude to Health', 'China', 'Cultural Characteristics', 'Family', 'Health Services Accessibility', 'Humans', 'Transcultural Nursing', 'United States'] | 1,293,204 | [['F01.100.150', 'N05.300.150'], ['Z01.252.474.164'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['F01.829.263', 'I01.880.853.150'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.478.676.920'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
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