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Ex Vivo characterization of canine liver tissue viscoelasticity after high-intensity focused ultrasound ablation. | The potential of elasticity imaging to detect high-intensity focused ultrasound (HIFU) lesions on the basis of their distinct biomechanical properties is promising. However, information on the quantitative mechanical properties of the tissue and the optimal intensity at which to determine the best contrast parameters i... | ['Animals', 'Dogs', 'Elastic Modulus', 'Elasticity Imaging Techniques', 'Hardness', 'Hepatectomy', 'High-Intensity Focused Ultrasound Ablation', 'Image Interpretation, Computer-Assisted', 'In Vitro Techniques', 'Liver', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Shear Strength', 'Viscosity'] | 24,315,395 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.374.590.605'], ['E01.370.350.850.270'], ['G01.374.647'], ['E04.210.556'], ['E02.565.280.945.399', 'E04.014.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E05.481'], ['A03.620'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Outcomes after unrestricted use of everolimus-eluting stent compared to paclitaxel- and sirolimus-eluting stents. | Compared to paclitaxel-eluting stents (PESs) and sirolimus-eluting stents (SESs), a paucity of data exists regarding the clinical outcome of everolimus-eluting stents (EESs) in unselected patients with the entire spectrum of obstructive coronary artery disease. The present study cohort included 6,615 consecutive patien... | ['Aged', 'Coronary Artery Disease', 'Drug-Eluting Stents', 'Everolimus', 'Female', 'Humans', 'Immunosuppressive Agents', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Paclitaxel', 'Sirolimus', 'Thrombosis', 'Treatment Outcome'] | 21,497,782 | [['M01.060.116.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E07.695.750.500'], ['D02.540.505.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Helicobacter pylori and recurrent abdominal pain in children: is there any relation? | BACKGROUND: The role of Helicobacter pylori (HP) as a cause of recurrent abdominal pain (RAP) and gastrointestinal symptoms is controversial and there still remains a big debate whether to test and treat or not.AIM: To investigate the correlation between HP infection and RAP as well as other GI symptoms.METHODS: We con... | ['Abdominal Pain', 'Adolescent', 'Age Factors', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Recurrence', 'Risk Factors'] | 22,803,297 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.31... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arrhythmogenic Munchausen syndrome culminating in caffeine-induced ventricular tachycardia. | We report a patient with numerous abnormal electrocardiograms (ECGs) in both inpatient and outpatient settings. Our patient both simulated and stimulated her arrhythmias with an ECG rhythm generator and intentional caffeine intoxication. To our knowledge, this is the first report of caffeine overdose for arrhythmogenes... | ['Adult', 'Caffeine', 'Central Nervous System Stimulants', 'Female', 'Humans', 'Munchausen Syndrome', 'Tachycardia, Ventricular'] | 20,888,004 | [['M01.060.116'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D27.505.696.282', 'D27.505.954.427.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.875.375.600'], ['C14.280.067.845.940', 'C14.280.123.875.940', 'C23.550.073.845.940']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transplantation is a risk factor for acute kidney injury in patients undergoing total hip replacement arthroplasty for avascular necrosis: an observational study. | BACKGROUND: The increased number of patients undergoing transplantation has increased the number of transplant recipients undergoing total hip replacement arthroplasty (THRA). We have evaluated the association between transplantation and acute kidney injury (AKI) in patients undergoing THRA.METHODS: Patients who underw... | ['Acute Kidney Injury', 'Adult', 'Aged', 'Arthroplasty, Replacement, Hip', 'Biomarkers', 'Chi-Square Distribution', 'Creatinine', 'Female', 'Humans', 'Kidney Transplantation', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Odds Ratio', 'Osteonecrosis', 'Propensity Score', 'Retrospective Studies', '... | 23,953,532 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D23.101'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D03.383.129.308.207'], ['B01.050.150.900.649.313.988.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhanced hormonal responsiveness in mammary glands from parous mice: molecular mechanisms. | Mammary glands from parous mice required lower concentrations of hormones in vitro than those from virgins to effect differentiation, as measured by lactose synthetase activity. This phenomenon could not be explained by changes in receptor levels, since both mammary gland insulin and prolactin binding, although elevate... | ['Animals', 'Caseins', 'Deoxyribonuclease I', 'Endodeoxyribonucleases', 'Epithelium', 'Ethidium', 'Female', 'Globins', 'Liver', 'Mammary Glands, Animal', 'Mice', 'Mice, Inbred C3H', 'Pregnancy', 'Pregnancy, Animal', 'RNA', 'Receptors, Cell Surface'] | 6,203,788 | [['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['D08.811.277.352.335.350.250'], ['D08.811.277.352.335.350', 'D08.811.277.352.355.325'], ['A10.272'], ['D03.633.300.633.416'], ['D12.776.422.316'], ['A03.620'], ['A10.336.482', 'A13.589'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.52... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RNA-seq reveals the downregulated proteins related to photosynthesis in growth-inhibited rice seedlings induced by low-energy N+ beam implantation. | Transcriptomic research based on RNA sequencing (RNA-seq) technology is innovative and will provide new opportunities and biological perspectives for the use of ion-beam implantation in plants. Using RNA-seq, transcriptomes of whole rice seedlings generated from seeds implanted with a low-energy N+ beam were analyzed 9... | ['Computational Biology', 'Down-Regulation', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Genome, Plant', 'Germination', 'Metabolic Networks and Pathways', 'Molecular Sequence Annotation', 'Oryza', 'Photosynthesis', 'Plant Roots', 'Quantitative Trait, Heritable', 'Radiation, Ionizing', 'Seedlings'... | 24,737,518 | [['H01.158.273.180', 'L01.313.124'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E05.393.332'], ['G05.308.375'], ['G05.360.340.365'], ['G07.345.625.249', 'G15.357'], ['G03.493'], ['E05.393.760.479', 'L01.453.245.667.580'], ['B01.650.940.800.575.912.250.822.616'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740... | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Migrating myoelectric complex and jejunal slow-wave propagation after Roux gastrectomy in dogs. | Roux-en-Y gastrectomy is associated with a high incidence of symptoms of gastric stasis. Retrograde propagation of jejunal electrical slow waves and spike bursts has been implicated in the Roux Y stasis syndrome. Since the fasted state may persist after feeding, this study examined the extent of retrograde slow-wave pr... | ['Anastomosis, Roux-en-Y', 'Animals', 'Dogs', 'Electrodes, Implanted', 'Fasting', 'Gastrectomy', 'Jejunum', 'Myoelectric Complex, Migrating', 'Postgastrectomy Syndromes', 'Postoperative Period'] | 8,508,702 | [['E04.035.070', 'E04.210.070'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['E07.305.250.319', 'E07.695.202'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['E04.210.419'], ['A03.556.124.684.500', 'A03.556.249.750'], ['G07.265.675.775', 'G10.261.360.570', 'G11.427.494.730', 'G11.56... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Effects of Nd:YAG laser irradiation on acid resistance of defective rat enamel]. | As Colchicine is an inhibitor of the function of microtubles, administration of it causes abnormal amelogenesis in the teeth of experimental animals. The purposes of this study were to characterize the defective rat enamel which was formed after a single administration of colchicine, and to examine the effects of Nd:YA... | ['Amelogenesis', 'Animals', 'Colchicine', 'Dental Enamel', 'Laser Therapy', 'Rats', 'Rats, Inbred Strains', 'Surface Properties', 'Tooth Demineralization', 'Tooth Diseases'] | 2,134,131 | [['G07.345.500.325.377.750.190'], ['B01.050'], ['D03.132.225'], ['A14.549.167.900.255'], ['E02.594', 'E04.014.520'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G02.860'], ['C07.793.720'], ['C07.793']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Light microscopic investigations on lysozyme- and penicillin-induced morphological changes in Erysipelothrix rhusiopathiae and on propagation of its protoplast type L-form. | Although lysozyme and penicillin are different in their molecular action on cell wall murein they produce similar morphological changes in Erysipelothrix rhusiopathiae grown on agar media. 2,000--5,000 micrograms/ml lysozyme and 0.1--2 IU/ml penicillin induce filament formation. Filaments are able to divide in rods, wh... | ['Erysipelothrix', 'L Forms', 'Microscopy', 'Muramidase', 'Penicillins'] | 7,434,791 | [['B03.353.688', 'B03.510.460.400.410.350'], ['B03.110.422', 'B05.110.422'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['D08.811.277.450.642'], ['D02.065.589.099.750', 'D02.886.108.750', 'D03.633.100.300.750']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Phylogenetic characterization of culturable bacterial diversity associated with the mucus and tissue of the coral Acropora digitifera from the Gulf of Mannar. | Corals, considered the rainforests of the oceans, harbour an abundance of different bacterial populations throughout the coral structure. In the present study we attempted to characterize the cultivable bacterial population associated within the mucus and tissue of the coral Acropora digitifera from the Gulf of Mannar.... | ['Animals', 'Anthozoa', 'Anti-Infective Agents', 'Bacteria', 'Colony Count, Microbial', 'DNA Restriction Enzymes', 'DNA, Bacterial', 'Microbial Sensitivity Tests', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Seawater', 'Sequence Analysis, DNA', 'Water Microbiology'] | 19,619,231 | [['B01.050'], ['B01.050.500.308.237'], ['D27.505.954.122'], ['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.212'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G05.697', 'G16.075.605', 'L01.100.697'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Extraventricular neurocytomas: pathologic features and clinical outcome. | Neurocytic neoplasms usually arise within the lateral ventricles, generally as circumscribed, slowly growing masses curable by total resection. Both subtotal resection and histologic atypia are associated with an increased risk of recurrence. In contrast, neurocytic neoplasms situated within brain parenchyma, so-called... | ['Adolescent', 'Adult', 'Aged', 'Antigens, Nuclear', 'Biomarkers, Tumor', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Combined Modality Therapy', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Mitotic Index', 'Neoplasm Recurrence, Local', 'Neurocytoma', 'Nuclear Proteins', 'Radiotherapy, Adjuv... | 11,688,459 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.660.625', 'D23.050.290'], ['D23.101.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Thrombin generation and platelet activation in cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy - A prospective cohort study. | BACKGROUND AND OBJECTIVES: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal peroperative chemotherapy (HIPEC), indicated for patients with peritoneal metastases from digestive or gynecological malignancies alike, demonstrates a considerable impact on hemostatic metabolism, both on platelet and on coagulati... | ['Adult', 'Aged', 'Cytoreduction Surgical Procedures', 'Female', 'Humans', 'Hyperthermia, Induced', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Peritoneal Neoplasms', 'Platelet Activation', 'Prospective Studies', 'Thrombelastography', 'Thrombin', 'Thrombin Time'] | 29,927,924 | [['M01.060.116'], ['M01.060.116.100'], ['E04.166'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['C04.588.033.513', 'C04.588.274.780', 'C06.301.780', 'C06.844.620'], ['G09.188.390.600'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extending FRET cascades on linear DNA photonic wires. | Photonic wires were constructed by sequentially arranging up to 7 fluorophores along a concatenated DNA scaffold. This yielded nanostructures displaying from one- to six-energy transfer steps where end-to-end efficiency reflected the multiple underlying photophysical processes and the ability of long-range interactions... | ['DNA', 'Fluorescence Resonance Energy Transfer', 'Nanowires', 'Photons'] | 24,752,334 | [['D13.444.308'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['J01.637.512.925'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Serum concentrations of vascular endothelial growth factor in relation to retinopathy of prematurity. | BACKGROUND: The role of vascular endothelial growth factor (VEGF) in the pathogenesis of retinopathy of prematurity (ROP) has been clearly established. However, little is known about temporal changes in circulating VEGF concentrations in the preterm infant. The objective was to determine the longitudinal serum concentr... | ['Comorbidity', 'Female', 'Fetal Blood', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Infant, Premature', 'Laser Therapy', 'Male', 'Pilot Projects', 'Prospective Studies', 'Retinopathy of Prematurity', 'Vascular Endothelial Growth Factor A'] | 26,372,519 | [['N05.715.350.225', 'N06.850.490.687'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['M01.060.703.520.520'], ['E02.594', 'E04.014.520'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.... | ['Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila | The ecdysone pathway was among the first experimental systems employed to study the impact of steroid hormones on the genome. In Drosophila and other insects, ecdysone coordinates developmental transitions, including wholesale transformation of the larva into the adult during metamorphosis. Like other hormones, ecdyson... | ['Animals', 'DNA-Binding Proteins', 'Drosophila', 'Drosophila Proteins', 'Ecdysone', 'Gene Expression Regulation, Developmental', 'Genome, Insect', 'Metamorphosis, Biological', 'Receptors, Steroid', 'Transcription Factors', 'Wings, Animal'] | 31,019,084 | [['B01.050'], ['D12.776.260'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['D04.210.500.247.222.265.165.500', 'D06.472.445.573.271.500'], ['G05.308.310'], ['G05.360.340.357'], ['G07.345.500.550'], ['D12.776.826.750', 'D12.776.930.778'], ['D12.776.930'], ['A13.395.823']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of aristolochic acid in nine sources of Xixin, a traditional Chinese medicine, by liquid chromatography/atmospheric pressure chemical ionization/tandem mass spectrometry. | Aristolochic acid I (AA-I), which is a known nephrotoxin, is found in a commonly used Chinese medicine, Xixin, that originates from nine Asarum species (Aristolochiaceae) found in China. A method has been developed using reversed-phase liquid chromatography coupled with atmospheric pressure chemical ionization (APCI) t... | ['Aristolochic Acids', 'Chromatography, High Pressure Liquid', 'Drugs, Chinese Herbal', 'Medicine, Chinese Traditional', 'Spectrometry, Mass, Electrospray Ionization'] | 14,623,612 | [['D02.455.426.559.847.723.089', 'D02.640.139', 'D04.615.723.089'], ['E05.196.181.400.300'], ['D20.215.784.500.350', 'D26.335'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['E05.196.566.600']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Histophysiological study of vasectomized rats. | An histophysiological evaluation was performed of adult rat testes 30 days after vasectomy. A higher frequency of stage VII-VIII of the tubular cycle was observed, indicating sperm accumulation. Seminiferous tubules and tubular lumen having increased diameters were also observed, but these results cannot be explained o... | ['Animals', 'Cell Cycle', 'Follicle Stimulating Hormone', 'Leydig Cells', 'Luteinizing Hormone', 'Male', 'Rats', 'Rats, Inbred Strains', 'Seminiferous Tubules', 'Spermatogenesis', 'Testis', 'Testosterone', 'Vasectomy'] | 6,434,010 | [['B01.050'], ['G04.144'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['A05.360.444.849.513', 'A06.300.312.782.513', 'A11.382.906', 'A11.436.513'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selection of reliable reference genes for gene expression study in nasopharyngeal carcinoma. | AIM: To construct a system for selecting reference genes (RGs) and to select the most optimal RGs for gene expression studies in nasopharyngeal carcinoma (NPC).METHODS: The total RNAs from 20 NPC samples were each labeled with Cy5-dUTP. To create a common control, the total RNA from 15 nasopharyngeal phlogistic (NP) ti... | ['Carcinoma', 'Gene Expression', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Oligonucleotide Array Sequence Analysis', 'RNA', 'Reverse Transcriptase Polymerase Chain Reaction'] | 21,052,085 | [['C04.557.470.200'], ['G05.297'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.470.200.623', 'C04.588.443.665.710.650.500', 'C07.550.350.650.500', 'C07.550.745.650.500', 'C09.647.710.650.500', 'C09.775.350.650.500', 'C09.775.549.650.500'], ['C04.588.443.665.710.650', 'C0... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Collateral flow in patients with acute myocardial infarction. | To assess the change in angiographically visualized collaterals in evolving acute myocardial infarction (AMI), coronary arteriograms from 53 patients obtained 6.2 +/- 0.2 hours after onset of AMI symptoms were compared with follow-up angiograms obtained 14 +/- 1 days later. Collaterals were graded according to intensit... | ['Aged', 'Angiography', 'Collateral Circulation', 'Coronary Circulation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction'] | 4,061,295 | [['M01.060.116.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['G09.330.100.248'], ['G09.330.100.324'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spontaneous and visible light-induced ultraweak photon emission from rat eyes. | Here, we present the first experimental in vitro evidence of the existence of spontaneous and visible light-induced ultraweak photon emission from freshly isolated whole eye, lens, vitreous humor, and retina samples from rats. These results suggest that the photochemical source of retinal discrete noise, as well as ret... | ['Animals', 'Biophysical Phenomena', 'Eye', 'Light', 'Luminescent Measurements', 'Photic Stimulation', 'Photons', 'Rats', 'Rats, Sprague-Dawley'] | 21,034,725 | [['B01.050'], ['G01.154'], ['A01.456.505.420', 'A09.371'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.196.712.516'], ['E05.723.729'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient and facile formation of two-component nanoparticles via aromatic moiety directed self-assembly. | Here we present a two-component self-assembling system employing the interaction of aromatic groups (Fmoc) to construct nanoparticles. Spherical particles of around 70 nm were formed spontaneously by a simple trigonal Fmoc-conjugate, which were then stabilized by Fmoc-dipeptides at physiological pH in aqueous solution.... | ['Fluorenes', 'Hydrodynamics', 'Nanoparticles', 'Nanotechnology', 'Spectrometry, Fluorescence'] | 21,523,312 | [['D02.455.426.559.847.389', 'D04.615.389'], ['G01.342'], ['J01.637.512.600'], ['H01.603', 'J01.897.520.600'], ['E05.196.712.516.600.676', 'E05.196.867.726']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
The role of Tc99m-sestamibi scintimammography in combination with the triple assessment of primary breast cancer. | AIM: The aim of this study was to evaluate if Tc99m-sestamibi scintimammography in addition to the triple assessment consisting of clinical examination, mammography, breast ultrasonography and fine needle aspiration cytology (FNA) enhances the diagnosis of breast cancer and helps in avoiding unnecessary operative biops... | ['Aged', 'Biopsy, Needle', 'Breast Neoplasms', 'Female', 'Humans', 'Mammography', 'Middle Aged', 'Neoplasm Staging', 'Radiographic Image Enhancement', 'Radionuclide Imaging', 'Sensitivity and Specificity', 'Statistics, Nonparametric', 'Technetium Tc 99m Sestamibi', 'Ultrasonography'] | 11,884,044 | [['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Electrocardiographic differential diagnosis of narrow QRS complex tachycardia: an ED-oriented algorithmic approach. | The differentiation of narrow complex tachycardias is a common diagnostic conundrum encountered by emergency physicians. Although a number of published algorithms are available to assist the clinician in evaluating features of the 12-lead electrocardiogram (ECG), many of these are too cumbersome, requiring multiple dec... | ['Algorithms', 'Diagnosis, Differential', 'Electrocardiography', 'Humans', 'Tachycardia'] | 20,223,399 | [['G17.035', 'L01.224.050'], ['E01.171'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Antimicrobial susceptibility and beta-lactamase production of anaerobic and aerobic bacteria isolated from pus specimens from orofacial infections. | Most suppurative orofacial infections are polymicrobial. Information regarding the antimicrobial susceptibility of the microorganisms involved can be useful in the choice of an effective antibiotic therapy. In this study we determined the antimicrobial susceptibility of a total 235 anaerobic and aerobic bacteria recent... | ['Anti-Bacterial Agents', 'Bacteria, Aerobic', 'Bacteria, Anaerobic', 'Bacterial Infections', 'Humans', 'Microbial Sensitivity Tests', 'Periodontal Diseases', 'Suppuration', 'Tooth Diseases', 'beta-Lactam Resistance', 'beta-Lactamases', 'beta-Lactams'] | 18,073,147 | [['D27.505.954.122.085'], ['B03.120'], ['B03.130'], ['C01.150.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['C07.465.714'], ['C01.830', 'C23.550.470.756'], ['C07.793'], ['G06.099.225.500', 'G06.225.347.500', 'G07.690.773.984.269.347.500'], ['D08.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparation of benzene, furan, and thiophene analogs of duocarmycin SA employing a newly-devised phenol-forming reaction. | Five A-ring analogs of duocarmycin SA 9a-e were synthesized in racemic form modifying our second synthetic route toward duocarmycin SA. The problem encountered at the crucial phenol forming step to secure 17a, b from 16a, b under the conventionally used Kuwajima conditions was overcome by devising a more convenient met... | ['Benzene', 'Duocarmycins', 'Furans', 'Indoles', 'Molecular Structure', 'Pyrroles', 'Spectrum Analysis', 'Thiophenes'] | 11,045,469 | [['D02.455.426.559.389.023'], ['D03.383.129.578.275', 'D03.633.100.473.278'], ['D03.383.312'], ['D03.633.100.473'], ['G02.111.570', 'G02.466'], ['D03.383.129.578'], ['E05.196.867'], ['D02.886.778', 'D03.383.903']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissecting the Pre-Columbian Genomic Ancestry of Native Americans along the Andes-Amazonia Divide. | Extensive European and African admixture coupled with loss of Amerindian lineages makes the reconstruction of pre-Columbian history of Native Americans based on present-day genomes extremely challenging. Still open questions remain about the dispersals that occurred throughout the continent after the initial peopling f... | ['Gene Flow', 'Genetic Variation', 'Genome, Human', 'Haplotypes', 'Human Migration', 'Humans', 'Indians, South American', 'Models, Genetic', 'Phylogeography', 'Polymorphism, Single Nucleotide', 'Principal Component Analysis', 'South America'] | 30,895,292 | [['G05.330.159'], ['G05.365'], ['G05.360.340.350'], ['G05.380.360'], ['I01.240.600.525', 'N01.224.625.525', 'N06.850.505.400.700.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.625'], ['E05.599.395.397'], ['H01.158.273.343.335.500', 'H01.277.500.589'], ['G05.365.795.598'], ['E05.318.740.562'],... | ['Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Recurrent idiopathic membranous glomerulonephritis. | This study reports the clinical and pathological findings in a patient with recurrent membranous glomerulonephritis following transplantation of an HLA-identical kidney. Such a recurrence has been previously reported only once, although membranous glomerulonephritis is a common cause of nephrotic syndrome in adults. Th... | ['Adult', 'Glomerulonephritis', 'Humans', 'Kidney Transplantation', 'Male', 'Recurrence', 'Time Factors', 'Transplantation, Homologous'] | 329,496 | [['M01.060.116'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['C23.550.291.937'], ['G01.910.857'], ['E04.936.864']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A syringe injection rate detector employing a dual Hall-effect sensor configuration. | Injection of fluids in the body using needle syringes is a standard clinical practice. The rate of injection can have various pathological effects on the body such as the pain perceived or in case of anesthesia, the amount of akinesia attained. Hence, a training system with a modified syringe employing a simple measure... | ['Humans', 'Injections', 'Needles', 'Pain', 'Syringes'] | 24,110,792 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['E07.612'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E07.877']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In situ solid-state (1)H NMR studies of hydration of the solid acid catalyst ZSM-5 in its ammonium form. | Hydration of the ammonium form of the solid acid catalyst ZSM-5 is investigated by applying a technique that has been developed recently for carrying out in situ solid-state NMR studies of adsorption processes. From (1)H MAS NMR spectra recorded as a function of time and temperature during the hydration process, insigh... | ['Acids', 'Computer Simulation', 'Magnetic Resonance Spectroscopy', 'Models, Chemical', 'Models, Molecular', 'Molecular Conformation', 'Protons', 'Quaternary Ammonium Compounds', 'Water', 'Zeolites'] | 19,231,141 | [['D01.029'], ['L01.224.160'], ['E05.196.867.519'], ['E05.599.495'], ['E05.599.595'], ['G02.111.570.820'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D01.625.062.500', 'D02.092.877', 'D02.675.276'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['D01.056... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983. | AIM: To investigate whether the immune response in colorectal liver metastases is related to progression free survival (PFS) and if this may be influenced by systemic therapy.METHODS: A retrospective central collection of tumour tissue was organised for the European Organisation for Research and Treatment of Cancer (EO... | ['Adult', 'Aged', 'Antigens, CD', 'Antigens, CD20', 'Antigens, Differentiation, Myelomonocytic', 'Antineoplastic Combined Chemotherapy Protocols', 'B-Lymphocytes', 'CD3 Complex', 'Chemotherapy, Adjuvant', 'Colorectal Neoplasms', 'Combined Modality Therapy', 'Disease-Free Survival', 'Female', 'Fluorouracil', 'Humans', '... | 26,342,674 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120', 'D23.101.100.150.120'], ['D23.050.301.264.900', 'D23.101.100.900'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['A11.063.438', 'A11.118.637.555... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Nurse's opinion on the applicability of the nursing process at the intensive care unit]. | This paper aimed to identify the nurses opinion about the nursing process in the Intensive Care Unit (ICU), and the knowledge they had about this such assistance methodology. The method of investigation used had an qualitative approach, of the descriptive and exploratory kind, applying semi structured interviews to fiv... | ['Critical Care', 'Humans', 'Intensive Care Units', 'Interviews as Topic', 'Nurses', 'Nursing Care'] | 11,993,100 | [['E02.760.190', 'N02.421.585.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.526.485.650', 'N02.360.650'], ['E02.760.611', 'N02.421.533']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Pseudotumoral mycobacterial infection in the head and neck: a clinical study. | The clinical aspects of mycobacterial infection of the head and neck are considered as presenting in patients at a cancer hospital over the last 15 years. Some difficulties in diagnosis with respect to the evolution of tuberculosis in this region are discussed. A total of 32 patients with evidence of infection were ide... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Diagnosis, Differential', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Mycobacterium Infections', 'Mycobacterium Infections, Nontuberculous', 'Nasal Cavity', 'Nasopharyngeal Diseases', 'Neck', 'Nose Diseases', 'Tuberculosis', 'Tuberculosis, Laryngeal',... | 3,973,497 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['E01.171'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.150.252.410.040.552'], ['C01.150.252.410.040.552.475'], ['A04.531.449'], ['C07.550.350', 'C09.775.350'], ['A01.598'], ['C08.460', 'C09.603'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy. | Atomic force microscopy (AFM)-based single molecule force spectroscopy is an ideal tool for investigating the interactions between a single polymer and surfaces. For a true single molecule experiment, covalent attachment of the probe molecule is essential because only then can hundreds of force-extension traces with on... | ['Microscopy, Atomic Force', 'Nanotechnology', 'Surface Properties'] | 32,225,151 | [['E01.370.350.515.666.400', 'E05.595.666.400'], ['H01.603', 'J01.897.520.600'], ['G02.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Successful desensitization with cetuximab after an infusion reaction to panitumumab in patients with metastatic colorectal cancer. | BACKGROUND: Cetuximab and panitumumab are chimeric and fully human monoclonal antibodies, respectively, against epidermal growth factor receptor used in the treatment of metastatic colorectal cancer (mCRC). Incidence of documented infusion reaction (IR) is more common with cetuximab (all grades [g]: 15-21%, g 3/4: 2-5%... | ['Adult', 'Aged', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Cetuximab', 'Colorectal Neoplasms', 'Desensitization, Immunologic', 'Drug Hypersensitivity', 'ErbB Receptors', 'Female', 'Humans', 'Infusions, Intravenous', 'Male', 'Neoplasm Metastasis', 'Panitumumab', 'Treatment... | 19,415,280 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['D12.776.124.486.485.114.224.060.750', 'D12.776.124.790.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of EACA, PAMBA, AMCA and AMBOCA on fibrinolysis induced by streptokinase, urokinase and tissue activator. | A study is presented in which the inhibiting effects of eACA, PAMBA, AMCA and AMBOCA on fibrinolysis induced by three activators have been compared by a clot lysis method. The order of inhibitory potency was AMBOCA greater than AMCA greater than PAMBA greater than EACA. The activity ratios obtained were found to be inf... | ['4-Aminobenzoic Acid', 'Aminocaproates', 'Aminocaproic Acid', 'Animals', 'Bridged Bicyclo Compounds', 'Depression, Chemical', 'Fibrinolysis', 'Humans', 'Plasminogen Activators', 'Streptokinase', 'Swine', 'Tranexamic Acid', 'Urokinase-Type Plasminogen Activator', 'para-Aminobenzoates'] | 6,982,199 | [['D02.241.223.100.050.500.640', 'D02.455.426.559.389.127.020.937.640'], ['D02.241.081.193.150', 'D12.125.213'], ['D02.241.081.193.150.075', 'D12.125.213.075'], ['B01.050'], ['D02.455.426.100.080', 'D04.075.080'], ['G07.690.773.750'], ['G09.188.390.150.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative determination of F6-1,25(OH)2 vitamin D3 in human serum by gas chromatography/mass spectrometry with high-resolution selected ion monitoring. | A highly sensitive and specific gas chromatographic/mass spectrometric method was developed for the determination of very low levels of F6-1,25(OH)2 vitamin D3, a new fluoro analogue of vitamin D3, to facilitate investigation of its pharmacokinetics in man. Deuterium-labelled F6-1,25(OH)2 vitamin D3 was employed as an ... | ['Calcitriol', 'Chromatography, High Pressure Liquid', 'Gas Chromatography-Mass Spectrometry', 'Half-Life', 'Humans', 'Isotope Labeling', 'Spectrophotometry, Ultraviolet'] | 8,155,746 | [['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['E05.196.181.400.300'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.522'], ['E05.196.712.726.802... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of Faculty Entrustment With Resident Autonomy in the Operating Room. | Importance: A critical balance is sought between faculty supervision, appropriate resident autonomy, and patient safety in the operating room. Variability in the release of supervision during surgery represents a potential safety hazard to patients. A better understanding of intraoperative faculty-resident interactions... | ['Clinical Competence', 'Data Collection', 'Faculty, Medical', 'Female', 'Humans', 'Internship and Residency', 'Interpersonal Relations', 'Male', 'Michigan', 'Operating Rooms', 'Professional Autonomy', 'Retrospective Studies', 'Specialties, Surgical'] | 29,466,559 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['M01.526.485.375', 'M01.526.702.250.373', 'N02.360.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F01.829.401'], ['Z01.107.567.875.350.500... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
[Epidural abscess after a cervical catheter]. | Epidural abscess following catheterization is a rare complication. When it occurs it usually affects cancer patients with poor or suppressed immune response or patients with sepsis. We present a healthy patient in whom an epidural cervical catheter was placed to provide analgesia during rehabilitation of an upper limb ... | ['Abscess', 'Adult', 'Analgesia, Epidural', 'Anti-Bacterial Agents', 'Catheters, Indwelling', 'Combined Modality Therapy', 'Diagnosis, Differential', 'Drug Therapy, Combination', 'Epidural Space', 'Equipment Contamination', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Meningitis, Bacterial', 'Staphylococcal Infecti... | 8,059,047 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.116'], ['E03.091.080'], ['D27.505.954.122.085'], ['E07.132.500'], ['E02.186'], ['E01.171'], ['E02.319.310'], ['A02.835.232.834.803.350'], ['N06.850.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C01.150.252.223.500', 'C01.207.180.500... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy of oxymatrine for treatment and relapse suppression of severe plaque psoriasis: results from a single-blinded randomized controlled clinical trial. | BACKGROUND: Drugs that are currently used in the treatment of psoriasis are associated with drawbacks such as rapid recrudescence, high costs and unwanted side-effects. Oxymatrine has a long history of clinical use in the treatment of hepatitis and cancer in China.OBJECTIVES: To explore the efficacy and safety of intra... | ['Acitretin', 'Adult', 'Alkaloids', 'Drug Administration Schedule', 'Female', 'Humans', 'Injections, Intravenous', 'Keratolytic Agents', 'Male', 'Psoriasis', 'Quality of Life', 'Quinolizines', 'Secondary Prevention', 'Single-Blind Method', 'Treatment Outcome'] | 28,112,799 | [['D02.455.326.271.665.202.495.050', 'D02.455.849.131.495.050', 'D23.767.261.700.050'], ['M01.060.116'], ['D03.132'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D27.505.954.444.400'], ['C17.800.859.675'], ['I01.800', 'K01.752.400.750', 'N06.850.50... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Spectral-domain optical coherence tomography enhanced depth imaging of the normal and glaucomatous nonhuman primate optic nerve head. | PURPOSE: To test whether the enhanced depth imaging (EDI) modality improves anterior and posterior lamina cribrosa surface (ALCS and PLCS) visibility compared with conventional spectral-domain optical coherence tomography (SD-OCT).METHODS: Conventional and EDI SD-OCT scans were obtained 30 minutes after IOP was manomet... | ['Animals', 'Axons', 'Disease Models, Animal', 'Female', 'Glaucoma', 'Intraocular Pressure', 'Macaca mulatta', 'Male', 'Optic Disk', 'Optic Nerve Diseases', 'Retinal Ganglion Cells', 'Tomography, Optical Coherence'] | 22,159,003 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C11.525.381'], ['G14.440'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['C10.292.700', 'C11.640'], ['A08.675.650.850.875'... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The risk for malignant primary adult-onset glioma in a large, multiethnic, managed-care cohort: cigarette smoking and other lifestyle behaviors. | PURPOSE: To determine the risk for malignant primary adult-onset glioma (MPAG) associated with cigarette smoking and other lifestyle behaviors in a large, multiethnic, managed-care cohort.METHODS: The study population included a cohort of 133,811 subscribers to the Kaiser Permanente Medical Care Program of Northern Cal... | ['Adult', 'Age of Onset', 'Aged', 'Behavior', 'Brain Neoplasms', 'California', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Glioma', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Risk Factors', 'Smoking', 'Surveys and Questionnaires'] | 15,174,522 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['F01.145'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Results of vacuum sealing therapy in joint infections]. | AIM: At present the vacuum sealing technique is acknowledged as a therapy for acute and chronic wounds. An acceleration of the healing process, due to the vacuum suction with occlusive wound dressing, leads to the shortening of a cost-effective medical treatment. This can be applied to wound treatment and infections of... | ['Abscess', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Arthritis, Infectious', 'Bacterial Infections', 'Child', 'Debridement', 'Female', 'Humans', 'Male', 'Middle Aged', 'Occlusive Dressings', 'Polyvinyl Alcohol', 'Postoperative Care', 'Reoperation', 'Surgical Sponges', 'Surgical Wound Infection', 'Vacuum Cur... | 17,187,335 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.100', 'C05.550.114.099'], ['C01.150.252'], ['M01.060.406'], ['E04.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.101.650'], ['D02.033.750', 'D02.455.326.271.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Efficacy and safety of dabigatran in patients with atrial fibrillation scheduled for transoesophageal echocardiogram-guided direct electrical current cardioversion: a prospective propensity score-matched cohort study. | Patients with atrial fibrillation (AF) are predisposed to a hypercoagulable state and are at an increased risk for thromboembolic events when undergoing procedures. This study investigated the long-term efficacy and safety of newly initiated anticoagulation with dabigatran versus uninterrupted vitamin K antagonist (VKA... | ['Adult', 'Aged', 'Atrial Fibrillation', 'Cohort Studies', 'Dabigatran', 'Echocardiography, Transesophageal', 'Electric Countershock', 'Female', 'Follow-Up Studies', 'Hemorrhage', 'Humans', 'Male', 'Middle Aged', 'Propensity Score', 'Prospective Studies', 'Thromboembolism', 'Treatment Outcome', 'Vitamin K'] | 29,260,427 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D03.383.725.192', 'D03.633.100.103.280'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E02.331.350'], ['E05.318.372.500.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Projections of single retinal ganglion cells to the visual centers: an intracellular staining study in a plethodontid salamander. | The projection specificity of retinal ganglion cells and the morphology of their terminals were studied in the plethodontid salamander Plethodon jordani. In an in vitro approach, ganglion cells were stained with biocytin and reconstructed by means of light microscopy. Single retinal ganglion cells often have multiple t... | ['Animals', 'Iontophoresis', 'Nerve Endings', 'Nerve Fibers', 'Retinal Ganglion Cells', 'Staining and Labeling', 'Superior Colliculi', 'Urodela', 'Visual Pathways'] | 10,349,965 | [['B01.050'], ['E02.319.267.650', 'E05.301.300.575'], ['A08.800.550'], ['A08.675.542', 'A11.671.501'], ['A08.675.650.850.875', 'A09.371.729.831.875', 'A11.671.650.850.875'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670'], ['A08.186.211.132.659.800.816'], ['B01.050.1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activity of cefsulodin, other beta-lactams, and aminoglycosides against Pseudomonas aeruginosa. | Cefsulodin was the most active of the cephalosporins and exhibited 4-16 times more activity than carbenicillin or ticarcillin against 50 clinical isolates of Pseudomonas aeruginosa. Azlocillin and piperacillin showed good activity, while tobramycin was the most effective aminoglycoside. The activity of cefsulodin was u... | ['Aminoglycosides', 'Anti-Bacterial Agents', 'Cefsulodin', 'Cephalosporins', 'Drug Resistance, Microbial', 'Drug Synergism', 'Gentamicins', 'Humans', 'Microbial Sensitivity Tests', 'Penicillin Resistance', 'Pseudomonas aeruginosa', 'Tobramycin'] | 6,428,812 | [['D09.408.051'], ['D27.505.954.122.085'], ['D02.065.589.099.249.185', 'D02.886.665.074.185', 'D03.633.100.300.249.185'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['G06.225', 'G07.690.773.984.269'], ['G07.690.773.968.477'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Continuing the debate on a separate adolescent psychiatry. | OBJECTIVE: This paper continues the debate, started by George Patton, that a separate adolescent psychiatry is required since many psychotic illnesses begin in late adolescence, and adolescent mental health needs have not been well met by child or adult psychiatry.METHOD: Epidemiological studies are used to illustrate ... | ['Adolescent', 'Adolescent Psychiatry', 'Adult', 'Australia', 'Cross-Sectional Studies', 'Forecasting', 'Health Planning', 'Health Services Needs and Demand', 'Humans', 'Incidence', 'Mental Disorders', 'Personality Development'] | 9,272,251 | [['M01.060.057'], ['F04.096.544.065', 'H02.403.690.080'], ['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.320'], ['N03.349', 'N03.706.615.302'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Cancer of the oral cavity: a comparison between institutions in a developing and a developed nation. | BACKGROUND: The literature suggests that the natural history of squamous cell carcinoma of the oral cavity may vary and the prognosis is different in patients from developing and developed nations. The objective of this study was to compare the clinical presentation, management, and outcome of patients with oral cancer... | ['Alcohol Drinking', 'Brazil', 'Carcinoma, Squamous Cell', 'Developed Countries', 'Developing Countries', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Multivariate Analysis', 'Neoplasms, Second Primary', 'Postoperative Complications', 'Prospective Studies', 'Sex Distribution',... | 14,724,904 | [['F01.145.317.269'], ['Z01.107.757.176'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['I01.615.500.250'], ['I01.615.500.300'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.4... | ['Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effects of thrombin on insulin signalling and glucose uptake in cultured human myotubes. | BACKGROUND: Hyper-coagulability (elevated thrombin) is a feature of type 2 diabetes and contributes to an increased risk of thrombotic and vascular events. Skeletal muscle is the key peripheral tissue site of insulin resistance in type 2 diabetes. Cultured human skeletal muscle cells were used to explore the effects of... | ['Adenylate Kinase', 'Cells, Cultured', 'Diabetes Mellitus, Type 2', 'Glucose', 'Humans', 'Insulin', 'Muscle Fibers, Skeletal', 'Protein Kinase C', 'Proto-Oncogene Proteins c-akt', 'Signal Transduction', 'Thrombin'] | 27,396,242 | [['D08.811.913.696.650.025'], ['A11.251'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A10.690.552.500.500', 'A11.620.249'], ['D08.811.913.696.620.682.700.725'], ['D08.811.913.696.620.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic contributions to precocity traits in racing Thoroughbreds. | Adaptation to early training and racing (i.e. precocity), which is highly variable in racing Thoroughbreds, has implications for the selection and training of horses. We hypothesised that precocity in Thoroughbred racehorses is heritable. Age at first sprint training session (work day), age at first race and age at bes... | ['Age Factors', 'Animals', 'Female', 'Genetic Association Studies', 'Genotype', 'Horses', 'Male', 'Myostatin', 'Phenotype', 'Physical Conditioning, Animal', 'Polymorphism, Single Nucleotide', 'Receptors, Serotonin'] | 29,230,835 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['E05.393.385'], ['G05.380'], ['B01.050.150.900.649.313.984.235.472'], ['D12.644.276.954.300.925', 'D12.776.467.942.300.925', 'D23.529.942.300.925'], ['G05.695'], ['G11.427.410.698.277.280'], ['G05.365.795.598'], ['D12.776.543.750.670.800', 'D12.776.543.750.695.800'... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Solubilization in mixed micelles studied by molecular dynamics simulations and COSMOmic. | Up to now, micelles composed of different surfactants (mixed micelles) are rarely studied with molecular methods. This is in contrast to their importance for pharmaceutical or industrial applications, where it is of great interest to predict the partition behavior for a large set of solutes (screening) within mixed mic... | ['Cetrimonium', 'Cetrimonium Compounds', 'Micelles', 'Molecular Dynamics Simulation', 'Polyethylene Glycols', 'Sodium Dodecyl Sulfate', 'Surface-Active Agents', 'Water'] | 24,533,791 | [['D02.092.877.883.111.500', 'D02.675.276.190.500'], ['D02.092.877.883.111', 'D02.675.276.190'], ['D05.374', 'D26.255.560'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D02.033.415.220.720', 'D02.886.645.600.055.050.632', 'D1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
T cell receptor repertoire and mitotic responses of lamina propria T lymphocytes in inflammatory bowel disease. | Human intestinal lamina propria T lymphocytes (LPL-T) physiologically exhibit minimal proliferation in response to antigen receptor stimulation in vitro. This is thought to occur as a consequence of regulatory influences which are exerted by the mucosal microenvironment. The present study is aimed at investigating whet... | ['Adolescent', 'Adult', 'Aged', 'Antibodies, Monoclonal', 'Colitis, Ulcerative', 'Crohn Disease', 'Female', 'Flow Cytometry', 'Humans', 'Inflammatory Bowel Diseases', 'Interleukin-2', 'Intestinal Mucosa', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Receptors, Antigen, T-Cell, alpha-beta', 'T-Lymphocytes'] | 8,050,181 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E01.370.225.500.363.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Refractures in cemented vertebrae after percutaneous vertebroplasty: a retrospective analysis. | Percutaneous vertebroplasty is an efficient procedure to treat pain due to osteoporotic vertebral compression fractures. However, refracture of cemented vertebrae occurs occasionally after vertebroplasty. It is unclear whether such fractures are procedure-related or part of the natural course of osteoporosis. The effec... | ['Aged', 'Bone Cements', 'Female', 'Follow-Up Studies', 'Fractures, Compression', 'Humans', 'Incidence', 'Logistic Models', 'Male', 'Osteoporosis', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Spinal Fractures', 'Treatment Outcome', 'Vertebroplasty'] | 18,204,942 | [['M01.060.116.100'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.59... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer. | BACKGROUND: The etiology of secondary cancer in childhood cancer survivors is largely unclear. Exposure of normal somatic cells to radiation and/or chemotherapy can damage DNA and if not all DNA lesions are properly fixed, the mis-repair may lead to pathological consequences. It is plausible to assume that genetic diff... | ['Adolescent', 'Adult', 'Blotting, Western', 'Cell Cycle Proteins', 'Child', 'Child, Preschool', 'DNA Damage', 'DNA Repair', 'Fibroblasts', 'Gene Expression Regulation, Neoplastic', 'Genome, Human', 'Humans', 'Infant', 'Infant, Newborn', 'Neoplasms, Second Primary', 'Protein Array Analysis', 'RNA, Messenger', 'Young Ad... | 21,991,345 | [['M01.060.057'], ['M01.060.116'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.167'], ['M01.060.406'], ['M01.060.406.448'], ['G05.200'], ['G02.111.222', 'G05.219'], ['A11.329.228'], ['G05.308.370'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Early stenosis in a Gore-Tex graft connected to the left main: an emergency transradial angioplasty for a complication in a Cabrol procedure. | This is a case report of a successful transradial percutaneous intervention in a stenosis in a Cabrol graft. Very few reports have been published about percutaneous interventional solutions to complications in this kind of graft, and none have used the transradial approach. The Cabrol technique is used to re-implant co... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Aorta', 'Aortic Valve', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Stenosis', 'Coronary Vessels', 'Echocardiography', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Polytetrafluoroethylene', 'Radial Artery', 'Saphenous Vein', 'Treatment Outcome'] | 23,043,039 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['A07.015.114.056'], ['A07.541.510.110'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Radioautographic investigation of monoaminergic neurons: an evaluation. | This review outlines the most relevant contributions currently available on the detection and ultrastructural characterization of monoaminergic neurons by radioautography after administration of radiolabeled monoamines. It includes methodological considerations and then a critical analysis of the diagnostic value of th... | ['Adrenergic Fibers', 'Animals', 'Autoradiography', 'Axons', 'Brain', 'Brain Mapping', 'Cats', 'Dopamine', 'Nerve Fibers', 'Neurons', 'Neurotransmitter Agents', 'Norepinephrine', 'Rats', 'Serotonin'] | 6,129,035 | [['A08.675.100.500', 'A08.675.542.075', 'A11.671.501.075'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stability of radiomic features of apparent diffusion coefficient (ADC) maps for locally advanced rectal cancer in response to image pre-processing. | Quantitative imaging features (radiomics) extracted from apparent diffusion coefficient (ADC) maps of rectal cancer patients can provide additional information to support treatment decision. Most available radiomic computational packages allow extraction of hundreds to thousands of features. However, two major factors ... | ['Diffusion Magnetic Resonance Imaging', 'Humans', 'Image Processing, Computer-Assisted', 'Observer Variation', 'Rectal Neoplasms', 'Tumor Burden'] | 31,151,578 | [['E01.370.350.825.500.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.405.469.491.307.790', 'C06.405.469.860.180.500'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Correlations of nuclear magnetic resonance imaging, computerized tomography, and clinical profiles in multiple sclerosis. | Nuclear magnetic resonance (NMR) imaging was superior to CT for imaging the brain lesions of 27 patients with MS. The incidence of abnormal examinations was 78% by NMR and 63% by CT. In cases in which both studies were abnormal, NMR usually demonstrated many more lesions and more extensive involvement than CT. The appe... | ['Adult', 'Brain', 'Female', 'Humans', 'Magnetic Resonance Spectroscopy', 'Male', 'Multiple Sclerosis', 'Tomography, X-Ray Computed'] | 3,941,780 | [['M01.060.116'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Four closely-related RING-type E3 ligases, APD1-4, are involved in pollen mitosis II regulation in Arabidopsis. | Ubiquitination of proteins is one of the critical regulatory mechanisms in eukaryotes. In higher plants, protein ubiquitination plays an essential role in many biological processes, including hormone signaling, photomorphogenesis, and pathogen defense. However, the roles of protein ubiquitination in the reproductive pr... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'Mitosis', 'Molecular Sequence Data', 'Pollen', 'Sequence Homology, Amino Acid', 'Ubiquitin-Protein Ligases'] | 22,897,245 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G04.144.220.220.781', 'G05.113.220.781'], ['L01.453.245.667'], ['A18.024.249.500.249.500'], ['G02.111.810.200', 'G05.810.200'], ['D08.811.464.938.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[A method of feating intermittent divergence strabismus (author's transl)]. | Patching appears to have sensory and motor effects on intermittent exotropia. The sensory effects we have observed are reduction in the size of the scotoma as measured on haploscopic devices and improvement in fusional amplitudes. The motor effects has been increased control of the deviation. A series of patients was s... | ['Adolescent', 'Child', 'Child, Preschool', 'Evaluation Studies as Topic', 'Eye Movements', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Occlusive Dressings', 'Orthoptics', 'Strabismus'] | 1,195,633 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.337', 'N05.715.360.335'], ['G11.427.410.140', 'G14.350'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.101.650'], ['E02.730', 'H02.573'], ['C10.292.562.887', 'C11.590.810']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Gray matter heterotopias: MR characteristics and correlation with developmental and neurologic manifestations. | Magnetic resonance (MR) images and clinical records of 20 patients with gray matter heterotopias were retrospectively reviewed to correlate MR characteristics of the heterotopias with clinical findings. On the basis of the MR images, patients were divided into three groups: those with subependymal heterotopias (eight p... | ['Adolescent', 'Adult', 'Brain', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Choristoma', 'Cognition', 'Humans', 'Infant', 'Intelligence', 'Magnetic Resonance Imaging', 'Middle Aged', 'Neurologic Examination', 'Paralysis', 'Psychomotor Performance', 'Retrospective Studies', 'Seizures', 'Speech'] | 1,732,969 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['C23.300.250'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.752.543'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E0... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Orally bioavailable potent soluble epoxide hydrolase inhibitors. | A series of N,N'-disubstituted ureas having a conformationally restricted cis- or trans-1,4-cyclohexane alpha to the urea were prepared and tested as soluble epoxide hydrolase (sEH) inhibitors. This series of compounds showed low nanomolar to picomolar activities against recombinant human sEH. Both isomers showed simil... | ['Adamantane', 'Administration, Oral', 'Animals', 'Benzoates', 'Biological Availability', 'Cats', 'Cricetinae', 'Dogs', 'Epoxide Hydrolases', 'Humans', 'Hypotension', 'In Vitro Techniques', 'Lipopolysaccharides', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Microsomes, Liver', 'Models, Molecular', 'Rats', 'Recombinant Protei... | 17,616,115 | [['D02.455.426.100.050', 'D02.455.426.392.368.075'], ['E02.319.267.100'], ['B01.050'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['G03.787.151', 'G07.690.725.129'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.750.250.216.200'], ['D08.811.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Whole-body positron emission tomography (PET) for diagnosis of residual mass in patients with lymphoma. | BACKGROUND: PET using 18fluorodesoxyglucose (FDG) may offer the possibility of differentiating vital from necrotic residual masses.PATIENTS AND METHODS: Seventeen patients with HD and 17 patients with NHL underwent FDG-PET following therapy. According to staging by routine methods at diagnosis, 7 patients presented sta... | ['Adult', 'Aged', 'Deoxyglucose', 'Fluorine Radioisotopes', 'Fluorodeoxyglucose F18', 'Hodgkin Disease', 'Humans', 'Lymphoma, Non-Hodgkin', 'Middle Aged', 'Neoplasm Staging', 'Neoplasm, Residual', 'Tomography, Emission-Computed', 'Whole-Body Counting'] | 9,187,431 | [['M01.060.116'], ['M01.060.116.100'], ['D09.254.229'], ['D01.496.749.340'], ['D09.254.229.500'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['E01.789.625'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The complete mitochondrial genome of the subterranean termite, Reticulitermes chinensis Snyder (Isoptera: Rhinotermitidae). | We have determined the complete mitochondrial genome of Reticulitermes chinensis Snyder. The total length of the R. chinensis is 15,925 bp with 65.27% A + T content. It consists of 13 protein-coding, 22 tRNA, 2 rRNA genes and an A + T-rich control region. All the protein-coding genes used ATN as start codon. But the st... | ['Animals', 'Base Composition', 'Genome Size', 'Genome, Insect', 'Genome, Mitochondrial', 'Isoptera', 'Mitochondria', 'Phylogeny', 'Sequence Analysis, DNA'] | 25,162,155 | [['B01.050'], ['G02.111.080'], ['G05.360.340.037'], ['G05.360.340.357'], ['G05.360.340.360'], ['B01.050.500.131.617.485'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Spectrum of genetic changes in patients with non-syndromic hearing impairment and extremely high carrier frequency of 35delG GJB2 mutation in Belarus. | The genetic nature of sensorineural hearing loss (SNHL) has so far been studied for many ethnic groups in various parts of the world. The single-nucleotide guanine deletion (35delG) of the GJB2 gene coding for connexin 26 was shown to be the main genetic cause of autosomal recessive deafness among Europeans. Here we pr... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Connexins', 'DNA, Mitochondrial', 'Female', 'Genotype', 'Hearing Loss', 'Hearing Loss, Sensorineural', 'Heterozygote', 'Humans', 'Infant', 'Male', 'Mutation', 'Republic of Belarus', 'Young Adult'] | 22,567,152 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['D12.776.543.585.250'], ['D13.444.308.283.225'], ['G05.380'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['G05.380.383'], ['B01.050.150... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The effects of the acetylcholinesterase inhibitor ENA713 and the M1 agonist AF150(S) on apolipoprotein E deficient mice. | Apolipoprotein E (apoE)-deficient and control mice were treated chronically with either the acetylcholinesterase (AChE) inhibitor ENA713, or the M1 muscarinic agonist AF150(S). Both treatments reversed the spatial working memory impairment of apoE-deficient mice but they differed in their effects on the levels of brain... | ['Animals', 'Apolipoproteins E', 'Carbamates', 'Cholinesterase Inhibitors', 'Cognition', 'Drug Evaluation, Preclinical', 'Histocytochemistry', 'Maze Learning', 'Mice', 'Mice, Inbred C57BL', 'Muscarinic Agonists', 'Phenylcarbamates', 'Piperidines', 'Rivastigmine', 'Thiazoles'] | 9,789,827 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['D02.241.081.251'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['F02.463.188'], ['E05.290.750', 'E05.337.550'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Phase 2 study of the combination of merimepodib with peginterferon-alpha2b, and ribavirin in nonresponders to previous therapy for chronic hepatitis C. | BACKGROUND/AIMS: While combination of peginterferon-alpha (PEG-IFN) and ribavirin (RBV) therapy is the current standard of care for chronic hepatitis C (CHC), only 44-51% of genotype-1 patients achieve a sustained virological response (SVR), and both agents produce treatment-limiting toxicities. In the hepatitis C viru... | ['Adult', 'Antiviral Agents', 'Carbamates', 'Drug Therapy, Combination', 'Female', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Interferon alpha-2', 'Interferon-alpha', 'Male', 'Middle Aged', 'Phenylurea Compounds', 'Placebos', 'Polyethylene Glycols', 'RNA, Viral', 'Recombinant Proteins', 'Ribavirin', 'Treatment O... | 17,629,590 | [['M01.060.116'], ['D27.505.954.122.388'], ['D02.241.081.251'], ['E02.319.310'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Interferon-beta bioactivity measurement in multiple sclerosis: feasibility for routine clinical practice. | BACKGROUND: Neutralising antibodies (NAb) to interferon beta (IFN beta) are associated with a reduced bioactivity and efficacy of IFN beta in multiple sclerosis (MS). Unclear is how to apply IFN beta bioactivity measurements (quantification of Myxovirus resistance protein A (MxA) mRNA) in clinical practice.OBJECTIVES: ... | ['Adult', 'Antibodies', 'Drug Monitoring', 'Feasibility Studies', 'Female', 'GTP-Binding Proteins', 'Gene Expression Regulation, Viral', 'Humans', 'Immunoassay', 'Immunologic Factors', 'Interferon-beta', 'Male', 'Middle Aged', 'Multiple Sclerosis, Relapsing-Remitting', 'Myxovirus Resistance Proteins', 'Neutralization T... | 18,805,837 | [['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E01.370.520.200'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['G05.308.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity. | Recently, we have developed a novel genetic platform for improving dendritic cell (DC) induction of peptide-specific CD8 T cells, based on membrane-anchored â2-microglobulin (â2m) linked to a selected antigenic peptide at its N-terminus and to the cytosolic domain of toll-like receptor (TLR)4 C-terminally. In vitro tra... | ['Animals', 'Antigen Presentation', 'Antigen-Presenting Cells', 'Antigens, Neoplasm', 'Antineoplastic Agents', 'Bone Marrow Cells', 'Cancer Vaccines', 'Cell Membrane', 'Cloning, Molecular', 'Culture Media', 'Cytosol', 'Dendritic Cells', 'Female', 'Histocompatibility Antigens Class I', 'Humans', 'Lipopolysaccharides', '... | 25,997,427 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['A11.066', 'A15.382.066'], ['D23.050.285'], ['D27.505.954.248'], ['A11.148', 'A15.378.316'], ['D20.215.894.200'], ['A11.284.149'], ['E05.393.220'], ['D27.720.470.305', 'E07.206'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['A11.066.270', 'A... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photochemistry of linear-shaped phenylacetylenyl- and (phenylacetylenyl)phenylacetylenyl-substituted aromatic enediynes. | The series of linear-shaped phenylacetylenyl- and (phenylacetylenyl)phenylacetylenyl-substituted aromatic enediynes 1-3 were synthesized as pure trans and cis isomers and their photochemistry explored. With expansion of the ð-electron system, the absorption spectra red-shifted and the molar extinction coefficients dram... | ['Enediynes', 'Fluorometry', 'Photochemistry', 'Spectrometry, Fluorescence', 'Spectrophotometry, Ultraviolet', 'Stereoisomerism'] | 20,873,752 | [['D02.455.326.271.244', 'D02.455.326.397.680.500.500'], ['E05.196.712.516.600'], ['H01.181.529.711'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
HSDPA (3.5G)-based ubiquitous integrated biotelemetry system for emergency care. | We have developed the second prototype system of Ubiquitous Integrated Biotelemetry System for Emergency Care(UIBSEC) using a HSDPA(High Speed Downlink Packet Access) modem to be used by emergency rescuers to get directions from medical doctors in providing emergency medical services for patients in ambulance. Five vit... | ['Computer Communication Networks', 'Emergency Medical Services', 'Equipment Design', 'Equipment Failure Analysis', 'Monitoring, Physiologic', 'Pilot Projects', 'Signal Processing, Computer-Assisted', 'Systems Integration', 'Telemedicine', 'Telemetry'] | 18,002,792 | [['L01.224.230.110'], ['N02.421.297'], ['E05.320'], ['E05.325.192'], ['E01.370.520'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['L01.224.800'], ['H01.770.787', 'L01.906.787'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800'], ['E01.370.520.750', 'E05.925', 'L01.178.847.675'... | ['Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Endoplasmic reticulum Ca(2+) signaling and calpains mediate renal cell death. | The goal of the current study was to determine the roles of ATP content, endoplasmic reticulum (ER) Ca(2+) stores, cytosolic free Ca(2+) (Ca(2+)(f)) and calpain activity in the signaling of rabbit renal proximal tubular (RPT) cell death (oncosis). Increasing concentrations (0.3-10 microM) of the mitochondrial inhibitor... | ['Adenosine Triphosphate', 'Animals', 'Antimycin A', 'Apoptosis', 'Calcium', 'Calcium Signaling', 'Calcium-Transporting ATPases', 'Calpain', 'Cells, Cultured', 'Endoplasmic Reticulum', 'Estrenes', 'Indoles', 'Kidney Tubules, Proximal', 'Pyrrolidinones', 'Rabbits', 'Thapsigargin', 'Type C Phospholipases'] | 12,058,278 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D02.540.576.500.750'], ['G04.146.954.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Drosophila sperm motility in the reproductive tract. | Motile cilia and flagella exhibit many waveforms as outputs of dynein activation sequences on the highly conserved axoneme. Motility change of sperm in the reproductive tract is difficult to study and remains an important area of investigation. Sperm typically execute a sinusoidal waveform. Increased viscosity in the m... | ['Adnexa Uteri', 'Animals', 'Animals, Genetically Modified', 'Drosophila melanogaster', 'Female', 'Fertilization', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Insect Proteins', 'Male', 'Microscopy, Video', 'Models, Biological', 'Protein Kinases'... | 21,293,028 | [['A05.360.319.114'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G08.686.784.277'], ['G05.360.340.024.340.435'], ['D12.776.532.265'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['D12.776.093.500'], ['E01.370.350.515.690', 'E05.595.690', 'J01.897... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Inhibition of multidrug resistance by a new staurosporine derivative, NA-382, in vitro and in vivo. | The effects of a newly synthesized compound, N-ethoxycarbonyl-7-oxo-staurosporine (NA-382), on multidrug resistance in tumor cells were investigated. Protein kinase-inhibitory activity of NA-382 was lower but more selective to Ca2+/phospholipid-dependent protein kinase than that of staurosporine. NA-382 at noncytotoxic... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Alkaloids', 'Animals', 'Azides', 'Dihydropyridines', 'Doxorubicin', 'Drug Resistance', 'Drug Synergism', 'Female', 'Humans', 'In Vitro Techniques', 'Leukemia P388', 'Membrane Glycoproteins', 'Mice', 'Staurosporine', 'Tetradecanoylphorbol Acetate', 'Tumor Cell... | 8,095,855 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D03.132'], ['B01.050'], ['D01.625.100', 'D02.159'], ['D03.383.725.203'], ['D02.455.426.559.847.562.050.20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of interleukin 6 by human and murine recombinant interleukin 1 in mice. | Interleukin (IL) 6 is a pleistropic cytokine with activities, among others, on immune cells, hematopoietic precursor cells and hepatocytes. We have investigated the kinetics and amplitude of its in vivo induction in mice after injection of four different IL 1 species as well as murine (m) and human (h) tumor necrosis f... | ['Animals', 'Dose-Response Relationship, Drug', 'Humans', 'Interleukin-1', 'Interleukin-6', 'Lipopolysaccharides', 'Mice', 'Mice, Inbred C57BL', 'Recombinant Proteins', 'Species Specificity', 'Tumor Necrosis Factor-alpha'] | 2,318,254 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrochemical Immunosensor Based on Nanoelectrode Ensembles for the Serological Analysis of IgG-type Tissue Transglutaminase. | Celiac disease (CD) is a gluten-dependent autoimmune disorder affecting a significant percentage of the general population, with increasing incidence particularly for children. Reliable analytical methods suitable for the serological diagnosis of the disorder are urgently required for performing both the early diagnosi... | ['Biosensing Techniques', 'Celiac Disease', 'Electrochemistry', 'Electrodes', 'GTP-Binding Proteins', 'Humans', 'Immunoassay', 'Immunoglobulin G', 'Transglutaminases'] | 30,862,087 | [['E05.601.043'], ['C06.405.469.637.250', 'C18.452.603.250'], ['H01.181.529.307'], ['E07.305.250'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl. | Thrombopoietin (Thpo) signaling through the c-Mpl receptor promotes either quiescence or proliferation of hematopoietic stem cells (HSCs) in a concentration-dependent manner; however, in vivo Thpo serum levels are responsive to platelet mass rather than HSC demands, suggesting additional regulation exists. Ott1 (Rbm15)... | ['Alternative Splicing', 'Animals', 'Cells, Cultured', 'Chromatin', 'Hematopoietic Stem Cell Transplantation', 'Hematopoietic Stem Cells', 'Humans', 'Mice', 'Mice, Knockout', 'NIH 3T3 Cells', 'Protein Isoforms', 'RNA, Messenger', 'RNA-Binding Proteins', 'Receptors, Thrombopoietin', 'Signal Transduction', 'Thrombopoieti... | 25,468,569 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['A11.251'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of the S267F variant on NTCP gene and treatment response to pegylated interferon in patients with chronic hepatitis B: a multicentre study. | BACKGROUND: Sodium taurocholate co-transporting polypeptide (NTCP) is a cell receptor for HBV. The S267F variant on the NTCP gene is inversely associated with the chronicity of HBV infection, progression to cirrhosis and hepatocellular carcinoma in East Asian populations. The aim of this study was to determine whether ... | ['Adult', 'Alleles', 'Amino Acid Substitution', 'Antiviral Agents', 'Biomarkers', 'Drug Therapy, Combination', 'Female', 'Genotype', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Interferon-alpha', 'Male', 'Middle Aged', 'Organic Anion Transporters, Sodium-Dependent', 'Pharmacogenomic Variants', 'Symporters',... | 28,635,613 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['E05.393.420.601.035', 'G05.558.109'], ['D27.505.954.122.388'], ['D23.101'], ['E02.319.310'], ['G05.380'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endoscopic pituitary surgery: Techniques, tips and tricks, nuances, and complication avoidance. | Endoscopic pituitary surgery is useful in all micro- and macro-pituitary adenomas including those with suprasellar and cavernous sinus extension. The endoscope provides a panoramic close-up, a multi-angled view with excellent illumination and magnification, permitting complete excision of the tumor with preservation of... | ['Adenoma', 'Endoscopy', 'Humans', 'Pituitary Neoplasms'] | 27,381,121 | [['C04.557.470.035'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C10.228.140.211.885.500.600', 'C10.228.140.617.477.600', 'C10.228.140.617.738.675', 'C10.551.240.250.700.500.500', 'C19.344.609', 'C19.700.734']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene structure of the ciliate Sterkiella histriomuscorum based on a combined analysis of DNA and cDNA sequences from 21 macronuclear chromosomes. | Macronuclear deoxyribonucleic acid (DNA) in hypotrichous ciliates consists of a set of linear molecules ranging in size from 0.5 to several tens of kilobases and typically carrying a single gene. Each minichromosome is present at a ploidy of >or=1,000 per macronucleus. These molecules are known as gene-sized molecules.... | ["3' Untranslated Regions", "5' Untranslated Regions", 'Animals', 'Base Sequence', 'Blotting, Southern', 'Chromosomes', 'Ciliophora', 'DNA', 'DNA, Complementary', 'Gene Expression', 'Gene Order', 'Introns', 'Molecular Sequence Data', 'Transcription Initiation Site'] | 16,091,962 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The experience of collaboration: a comparison of health visiting in Scotland and Norway. | This investigation compared health visiting in Scotland and Norway by focusing on collaboration in health visiting. The data are based upon in-depth interviews with a non-probability sample, with voluntary participation of nine health visitors from Scotland and 12 health visitors from Norway. The results showed that th... | ['Adult', 'Clinical Nursing Research', 'Community Health Nursing', 'Cooperative Behavior', 'Humans', 'Middle Aged', 'Norway', "Nurse's Role", 'Scotland'] | 12,243,591 | [['M01.060.116'], ['H01.770.644.145.390.234', 'H02.478.395.234', 'N04.590.233.508.613.234'], ['H02.478.676.150', 'N02.421.143.150'], ['F01.145.813.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.816.374'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['Z01.542.363.766']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Applied potential tomography in the measurement of gastric emptying in infants. | The aim of this study was to investigate the feasibility of using applied potential tomography (APT), a noninvasive and nonradioactive method, to measure the rate of gastric emptying in preterm babies and infants < 3 months old. APT, a form of electrical impedance tomography, creates tomographic images of tissue resist... | ['Bottle Feeding', 'Electric Impedance', 'Female', 'Gastric Emptying', 'Humans', 'Infant', 'Infant Food', 'Infant, Newborn', 'Infant, Premature', 'Intubation, Gastrointestinal', 'Male', 'Milk, Human', 'Tomography'] | 7,884,620 | [['E02.421.150', 'F01.145.407.099', 'G07.203.650.220.500.250', 'G07.203.650.353.099'], ['G01.358.500.249.277.350'], ['G10.261.360.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.203.300.525.500', 'J02.500.525.500'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['E02.585.412', 'E05.497.41... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
[The measured resection of an aneurysm of the ascending aorta with intima-saving aortic exoprosthesis]. | The aim of the study was simplification of the method of prosthetic reconstruction of the ascending aorta for its aneurysm by resection of mathematically calculated area of the aortic wall with creation of supporting prosthesis around the patient's own aorta to prevent development of the aneurysm in the future. 9 patie... | ['Adult', 'Aged', 'Aorta', 'Aorta, Abdominal', 'Aortic Aneurysm', 'Aortic Aneurysm, Abdominal', 'Blood Vessel Prosthesis Implantation', 'Extracorporeal Circulation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Suture Techniques', 'Tunica Intima'] | 9,680,797 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.056'], ['A07.015.114.056.205'], ['C14.907.055.239', 'C14.907.109.139'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E04.100.814.868.500', 'E04.650.200'], ['E04.292'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.987.775'], ['A07.0... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. | To analyze cellular reprogramming at the single-cell level, mass cytometry was used to simultaneously measure markers of pluripotency, differentiation, cell-cycle status, and cellular signaling throughout the reprogramming process. Time-resolved progression analysis of the resulting data sets was used to construct a co... | ['Animals', 'Antigens, Differentiation', 'Cellular Reprogramming Techniques', 'HEK293 Cells', 'Humans', 'Image Cytometry', 'Induced Pluripotent Stem Cells', 'Mice', 'Transcription Factors'] | 25,748,935 | [['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['E05.200.500.380', 'E05.242.378', 'E05.393.085'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.386.400', 'E05.196.712.516.600.240.400', 'E05.200.500.386.400', 'E05.242.386.400'], ['A11.872.040.500', 'A11.872... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oral contraception and cardiovascular risk factors during adolescence. | The objective of the present study was to analyze the pattern of oral contraceptive (OC) use in teenagers and to examine the relationship between OC use and other cardiovascular risk factors. The study was conducted in 24 Belgian secondary schools. Most students (1526 adolescents aged 12-17 years) agreed to participate... | ['Adolescent', 'Blood Pressure', 'Body Mass Index', 'Cardiovascular Diseases', 'Child', 'Contraceptives, Oral, Hormonal', 'Female', 'Humans', 'Male', 'Prevalence', 'Risk Factors', 'Smoking'] | 11,124,357 | [['M01.060.057'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['M01.060.406'], ['D27.505.696.875.360.276.210.277', 'D27.505.696.875.360.360.500', 'D27.505.954.705.360.276.210.277', 'D27.505.954.705.360.360.500'], ['B0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neutrophil CD64, TLR2 and TLR4 expression increases but phagocytic potential decreases during tuberculosis. | During initial stages of pathogen recognition during tuberculosis infection, neutrophils provide significant immune resistance. This is exhibited by phagocytosis of the pathogen, apoptosis, activation of downstream immune responses, etc. As pathogen recognition by neutrophil cell surface receptor and phagocytosis marks... | ['Adult', 'Case-Control Studies', 'Cells, Cultured', 'Female', 'Host-Pathogen Interactions', 'Humans', 'Male', 'Middle Aged', 'Mycobacterium tuberculosis', 'Neutrophils', 'Phagocytosis', 'Receptors, IgG', 'Signal Transduction', 'Toll-Like Receptor 2', 'Toll-Like Receptor 4', 'Tuberculosis, Pulmonary', 'Up-Regulation', ... | 30,029,898 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.251'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Contribution of the Xpert MTB/RIF to the etiological diagnosis of tuberculous pleurisy]. | INTRODUCTION: Performance of the Xpert MTB/RIF for the detection of Mycobacterium tuberculosis in pleural liquid is poorly described. The aim of this study was to determine its usefulness for the etiological diagnosis of a tuberculous pleurisy.PATIENTS AND METHOD: We performed a descriptive cross-sectional study, with ... | ['Adolescent', 'Adult', 'Aged', 'Biopsy', 'Cross-Sectional Studies', 'Drainage', 'Female', 'Humans', 'Male', 'Mass Screening', 'Microbiological Techniques', 'Middle Aged', 'Mycobacterium tuberculosis', 'Pleura', 'Tuberculosis, Pleural', 'Young Adult'] | 28,214,065 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.309', 'E04.237'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Heterogeneity of caffeine- and bradykinin-sensitive Ca2+ stores in vascular endothelial cells. | The filling state of Ca2+ stores in endothelial cells regulates Ca2+ entry. The functional relationship between the major Ca2+ stores [i.e. Ins(1,4,5)P3-sensitive (= bradykinin-sensitive stores, 'BsS') and caffeine-sensitive stores] is unknown. In pig right-coronary-artery endothelial cells, caffeine failed to release ... | ['Animals', 'Biological Transport', 'Bradykinin', 'Caffeine', 'Calcium', 'Calcium-Transporting ATPases', 'Cell Compartmentation', 'Cells, Cultured', 'Endoplasmic Reticulum', 'Endothelium, Vascular', 'In Vitro Techniques', 'Swine', 'Terpenes', 'Thapsigargin'] | 8,010,945 | [['B01.050'], ['G03.143'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.040.025.314.250', 'D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Diagnostic difficulties in a case of carcinomatous meningitis]. | A case of carcinomatous meningitis clinically suggesting an inflammatory process is described. The patient died unexpectedly of an intercurrent cause and the neuropathological examination allowed to recognize a early stage of carcinomatous infiltration of meninges. | ['Adult', 'Carcinoma', 'Fatal Outcome', 'Humans', 'Male', 'Meningeal Neoplasms', 'Meningitis', 'Pia Mater'] | 8,247,247 | [['M01.060.116'], ['C04.557.470.200'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C10.228.614'], ['A08.186.566.731']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparative study of incisor procumbency and mandibular morphology in vampire bats. | The three species of vampire bats (Phyllostomidae: Desmodontinae), Desmodus rotundus, Diaemus youngi, and Diphylla ecaudata, are the only mammals that obtain all nutrition from vertebrate blood (sanguinivory). Because of the unique challenges of this dietary niche, vampire bats possess a suite of behavioral, physiologi... | ['Analysis of Variance', 'Animals', 'Chiroptera', 'Feeding Behavior', 'Incisor', 'Mandible', 'Organ Size', 'Radiography'] | 20,544,874 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.150.900.649.313.937'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A14.549.167.860.425'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Chemoenzymatic Syntheses of Sialylated Oligosaccharides Containing C5-Modified Neuraminic Acids for Dual Inhibition of Hemagglutinins and Neuraminidases. | A fast chemoenzymatic synthesis of sialylated oligosaccharides containing C5-modified neuraminic acids is reported. Analogues of GM3 and GM2 ganglioside saccharidic portions where the acetyl group of NeuNAc has been replaced by a phenylacetyl (PhAc) or a propanoyl (Prop) moiety have been efficiently prepared with metab... | ['Agglutinins', 'Animals', 'Cattle', 'Escherichia coli', 'Hemagglutinins', 'Hydrolysis', 'Maackia', 'Metabolic Engineering', 'Neuraminic Acids', 'Neuraminidase', 'Oligosaccharides', 'Sialic Acids', 'Vibrio cholerae'] | 26,088,695 | [['D27.505.696.477.136', 'D27.505.954.502.270.232'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D27.505.696.477.136.377'], ['G02.380'], ['B01.650.940.800.575.912.250.401.581'], ['E05.393.420.526', 'E05.481.500.311.249', 'J01.293.069.249.249'], ['D02.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Study on mechanism of "Epimedii Folium-Paeoniae Radix Alba" in treatment of lumbar disc herniation based on network pharmacology]. | The aim of this paper was to investigate the key targets and mechanism of "Epimedii Folium-Paeoniae Radix Alba" in the treatment of lumbar disc herniation by means of network pharmacology. The currently recognized databases and analysis software at home and abroad were used to construct the network from drugs... | ['Drugs, Chinese Herbal', 'Epimedium', 'Humans', 'Intervertebral Disc Displacement', 'Lumbar Vertebrae', 'Medicine, Chinese Traditional', 'Paeonia', 'Plant Leaves', 'Plant Roots', 'Signal Transduction'] | 32,237,520 | [['D20.215.784.500.350', 'D26.335'], ['B01.650.940.800.575.912.250.125.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.900.307', 'C23.300.707.952'], ['A02.835.232.834.519'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['B01.650.940.800.575.912.250.791'], ['A18.024.812'], ['A18.400'], ['G02... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Genome-wide analysis of the RNA-DEPENDENT RNA POLYMERASE6/DICER-LIKE4 pathway in Arabidopsis reveals dependency on miRNA- and tasiRNA-directed targeting. | Posttranscriptional RNA silencing of many endogenous transcripts, viruses, and transgenes involves the RNA-DEPENDENT RNA POLYMERASE6/DICER-LIKE4 (RDR6/DCL4)-dependent short interfering RNA (siRNA) biogenesis pathway. Arabidopsis thaliana contains several families of trans-acting siRNAs (tasiRNAs) that form in 21-nucleo... | ['Arabidopsis', 'Arabidopsis Proteins', 'Base Sequence', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genome, Plant', 'MicroRNAs', 'Molecular Sequence Data', 'Nucleotides', 'RNA, Messenger', 'RNA, Small Interfering', 'RNA-Dependent RNA Polymerase', 'Ribonuclease III', 'Ribonucleases'] | 17,400,893 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.365'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['L01.453.245.667'], ['D09.408.620', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The 'fine line' of heat rejection. | Selection of heat rejection equipment has traditionally entailed a choice between the higher energy consumption of an air-cooled solution, and the high water consumption of a water-cooled solution. This paper examines advancement in heat rejection technology and the way it can be applied to air conditioning and refrige... | ['Air Conditioning', 'Health Facilities', 'Technology', 'United Kingdom'] | 20,882,904 | [['N06.230.150.050'], ['N02.278'], ['J01.897'], ['Z01.542.363']] | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Specificity of the clinical diagnosis of dementia. | The specificity of anatomo-clinical observations were investigated on 776 out of 982 consecutive persons hospitalized at the University Psychiatric Clinic of Geneva. Discriminant function analysis shows that most of the anatomical classes (no dementia, senile dementia, Alzheimerized senile dementia and Alzheimer's pres... | ['Age Factors', 'Aged', 'Alzheimer Disease', 'Basal Ganglia', 'Dementia', 'Female', 'Frontal Lobe', 'Hippocampus', 'Humans', 'Male', 'Middle Aged', 'Neurocognitive Disorders', 'Sex Factors', 'Terminology as Topic'] | 1,159,460 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211.200.885.287.249'], ['C10.228.140.380', 'F03.615.400'], ['A08.186.211.200.885.287.500.270'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Successful 96-Hr cold-storage preservation of canine pancreas with UW solution containing the thromboxane A2 synthesis inhibitor OKY046. | Prostanoids, such as prostacyclin (PGI) and thromboxane A2 (TxA), have been recently suggested to play an important role in preservation-induced injury of pancreas grafts. We have previously shown that the TxA synthesis inhibitor OKY046 prevents a decrease of both the PGI/TxA ratio and blood flow in pancreas grafts aft... | ['Adenosine', 'Allopurinol', 'Animals', 'Cold Temperature', 'Dogs', 'Epoprostenol', 'Female', 'Glutathione', 'Insulin', 'Male', 'Methacrylates', 'Organ Preservation', 'Organ Preservation Solutions', 'Pancreas Transplantation', 'Raffinose', 'Solutions', 'Thromboxane-A Synthase', 'Thromboxanes', 'Time Factors'] | 1,528,034 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D03.633.100.759.160'], ['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['B01.050.150.900.649.313.750.250.216.200'], ['D10.251.355.255.550.550.500', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of a novel dog adoption program in two US communities. | Millions of dogs enter animal welfare organizations every year and only a fraction of them are adopted. Despite the most recent American Pet Products Association (APPA) data that nearly half the US population owns a dog, only 20% acquired their dog from an animal welfare organization. Studies show that people consider ... | ['Adoption', 'Animal Welfare', 'Animals', 'Data Collection', 'Dogs', 'Geography', 'Residence Characteristics', 'Time Factors', 'United States'] | 24,663,804 | [['I01.880.853.150.140'], ['I01.880.604.100'], ['B01.050'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.750.250.216.200'], ['H01.277.500'], ['N01.224.791', 'N06.850.505.400.800'], ['G01.910.857'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
[Stress hyperglycemia in cats]. | It may be difficult to differentiate the possible causes of hyperglycemia in the cat. The following investigation was on transient hyperglycemia in 320 cats. The frequency and degree of stress-hyperglycemia and its relation to different types of primary diseases was proven. Animals with overt diabetes mellitus or pancr... | ['Animals', 'Cat Diseases', 'Cats', 'Female', 'Hyperglycemia', 'Insulin', 'Male', 'Stress, Physiological'] | 2,191,650 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C18.452.394.952'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G07.775']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abdominal tuberculosis: A retrospective analysis of 45 cases. | Abdominal tuberculosis is defined as infection of the peritoneum, hollow or solid abdominal organs with Mycobacterium tuberculosis. The peritoneum and the ileocaecal region are the most likely sites of infection and are involved in the majority of the cases by haematogenous spread or through swallowing of infected sput... | ['Abdomen', 'Abdominal Pain', 'Antitubercular Agents', 'Humans', 'Mycobacterium tuberculosis', 'Retrospective Studies', 'Sputum', 'Tuberculosis'] | 27,998,492 | [['A01.923.047'], ['C23.888.592.612.054', 'C23.888.821.030'], ['D27.505.954.122.085.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825',... | ['Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fiducial marker-based correction for involuntary motion in weight-bearing C-arm CT scanning of knees. II. Experiment. | PURPOSE: A C-arm CT system has been shown to be capable of scanning a single cadaver leg under loaded conditions by virtue of its highly flexible acquisition trajectories. In Part I of this study, using the 4D XCAT-based numerical simulation, the authors predicted that the involuntary motion in the lower body of subjec... | ['Algorithms', 'Artifacts', 'Calibration', 'Computer Simulation', 'Fiducial Markers', 'Four-Dimensional Computed Tomography', 'Humans', 'Knee', 'Leg', 'Models, Biological', 'Motion', 'Pattern Recognition, Automated', 'Phantoms, Imaging', 'Posture', 'Radiation Dosage', 'Radiographic Image Enhancement', 'Supine Position'... | 24,877,813 | [['G17.035', 'L01.224.050'], ['E05.047'], ['E05.978.155'], ['L01.224.160'], ['E05.978.808.249', 'E07.695.237', 'E07.710.259'], ['E01.370.350.350.810.490', 'E01.370.350.400.350', 'E01.370.350.700.700.810.490', 'E01.370.350.700.810.810.645', 'E01.370.350.825.810.810.599'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
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