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Antiviral activity of the EB peptide against zoonotic poxviruses. | BACKGROUND: The EB peptide is a 20-mer that was previously shown to have broad spectrum in vitro activity against several unrelated viruses, including highly pathogenic avian influenza, herpes simplex virus type I, and vaccinia, the prototypic orthopoxvirus. To expand on this work, we evaluated EB for in vitro activity... | ['Animals', 'Antiviral Agents', 'Cowpox', 'Cowpox virus', 'Disease Models, Animal', 'Ectromelia virus', 'Fibroblast Growth Factor 4', 'Humans', 'Mice', 'Microbial Sensitivity Tests', 'Oligopeptides', 'Survival Analysis', 'Treatment Outcome', 'Vaccinia', 'Viral Load', 'Viral Plaque Assay', 'Virus Attachment', 'Virus Int... | 22,225,618 | [['B01.050'], ['D27.505.954.122.388'], ['C01.925.256.743.175'], ['B04.280.650.160.650.150'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B04.280.650.160.650.200'], ['D12.644.276.624.140', 'D12.776.467.624.140', 'D12.776.624.664.700.110', 'D23.529.624.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Feeding preterm neonates with patent ductus arteriosus (PDA): intestinal blood flow characteristics and clinical outcomes. | OBJECTIVE: To evaluate the effects of patent ductus arteriosus (PDA) on postprandial superior mesenteric artery blood flow velocities (SMA BFV)s and feeding tolerance in extremely low birth weight (ELBW) neonates.METHODS: Appropriate for gestational age, ELBW preterm neonates, tolerating bolus enteral feedings were eli... | ['Blood Flow Velocity', 'Ductus Arteriosus, Patent', 'Enteral Nutrition', 'Female', 'Hemodynamics', 'Humans', 'Infant Nutritional Physiological Phenomena', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases', 'Intestines', 'Male', 'Prognosis', 'Regional Blood Flow'] | 24,824,108 | [['E01.370.370.130', 'G09.330.380.630.080'], ['C14.240.400.340', 'C14.280.400.340', 'C16.131.240.400.340'], ['E02.421.360', 'E02.642.500.360'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.220.500'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['C16.614.521'], ['A03.556.124'], ['E01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Amyloid pseudotumor treated by tracheal resection. | Primary amyloidosis is a rare disease, and even more so when it appears as a tumorlike formation in the lung or tracheobronchial tree. On rare occasions it has been treated by pulmonary resection but never before by tracheal or bronchial sleeve resection. A case of tracheal sleeve resection for tumorlike amyloidosis is... | ['Adult', 'Aged', 'Amyloidosis', 'Bronchoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Trachea', 'Tracheal Diseases'] | 869,631 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.845.500'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A04.889'], ['C08.907']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relationships between paced QRS duration and left cardiac structures and function. | BACKGROUND: In patients with congestive heart failure, QRS duration (QRSd) is correlated with left ventricular (LV) ejection fraction (LVEF), ventricular dyssynchrony and patients' prognosis. However, little is known about the relationships between paced QRS duration (pQRSd) to cardiac structures and function and ventr... | ['Aged', 'Atrial Function, Left', 'Atrioventricular Block', 'Cardiac Pacing, Artificial', 'Echocardiography, Doppler', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Heart Atria', 'Heart Conduction System', 'Heart Rate', 'Heart Ventricles', 'Humans', 'Male', 'Prognosis', 'Retrospective Studies', 'Stroke Volume'... | 19,476,117 | [['M01.060.116.100'], ['G09.330.040.100'], ['C14.280.067.558.230', 'C14.280.123.500.230', 'C23.550.073.425.062'], ['E02.331.200'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.71... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Finnish mothers' and fathers' reports of their boys and girls by using the Brief Infant-Toddler Social and Emotional Assessment (BITSEA). | This study investigated maternal and paternal reports about their very young boys and girls on the Brief Infant-Toddler Social and Emotional Assessment (BITSEA). Two samples were recruited through child health centers in Northern Finland. The infant sample consisted of 227 children (112 boys and 115 girls) (mean age 13... | ['Adolescent', 'Adult', 'Aging', 'Child Behavior Disorders', 'Child, Preschool', 'Emotions', 'Fathers', 'Female', 'Finland', 'Humans', 'Infant', 'Infant Behavior', 'Male', 'Mothers', 'Neuropsychological Tests', 'Reproducibility of Results', 'Social Behavior', 'Young Adult'] | 25,827,263 | [['M01.060.057'], ['M01.060.116'], ['G07.345.124'], ['F03.625.141'], ['M01.060.406.448'], ['F01.470'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.145.179.500'], ['F01.829.263.500.320.200', 'I01.8... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
High energy shock waves and 5-aminolevulinic for sonodynamic therapy: effects in a syngeneic model of colon cancer. | The cytotoxic effect of the natural porphyrin precursor 5-aminolevulinic acid (ALA) exposed to high energy shock waves (HESW) was investigated in vitro on DHD/K12/TRb rat colon cancer cells and in vivo on a syngeneic colon cancer model. In vitro, viable cell growth was determined by trypan blue exclusion assay and cell... | ['Aminolevulinic Acid', 'Animals', 'Apoptosis', 'Blotting, Western', 'Cell Line, Tumor', 'Cell Proliferation', 'Colorectal Neoplasms', 'Combined Modality Therapy', 'Flow Cytometry', 'Genes, bcl-2', 'High-Energy Shock Waves', 'In Situ Nick-End Labeling', 'Poly(ADP-ribose) Polymerases', 'RNA, Messenger', 'Rats', 'Reverse... | 21,214,291 | [['D02.241.755.547.276', 'D12.125.262'], ['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Downregulation of programmed cell death 4 by inflammatory conditions contributes to the generation of the tumor promoting microenvironment. | Ample evidence has shown key roles of inflammation in tumor promotion and carcinogenesis, and tumor-associated macrophages are known to promote tumor growth and dissemination. Programmed cell death 4 (Pdcd4) is a novel tumor suppressor, and although various studies have revealed that the functions and expression mechan... | ['Animals', 'Apoptosis', 'Carcinogens', 'Cell Line', 'Down-Regulation', 'Female', 'Humans', 'Interferon-gamma', 'Interleukin-10', 'Lipopolysaccharides', 'Macrophages', 'Macrophages, Peritoneal', 'Mice', 'Mice, Inbred ICR', 'Monocytes', 'RNA, Messenger', 'RNA, Small Interfering', 'Recombinant Proteins', 'Tumor Necrosis ... | 20,607,724 | [['B01.050'], ['G04.146.954.035'], ['D27.888.569.100'], ['A11.251.210'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.52... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cognitive fMRI and neuropsychological assessment in patients with secondarily generalized seizures. | OBJECTIVES: Cognitive dysfunction is a frequent comorbid disorder in epilepsy which has been associated with high seizure frequency. We examined the effect of secondarily generalized tonic-clonic seizures (SGTCS) on cognitive dysfunction using neuropsychological assessment and fMRI.PATIENTS AND METHODS: Sixteen patient... | ['Adult', 'Brain Mapping', 'Cognition Disorders', 'Epilepsy, Tonic-Clonic', 'Female', 'Frontal Lobe', 'Humans', 'Intelligence Tests', 'Linear Models', 'Magnetic Resonance Imaging', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Neuropsychological Tests', 'Prefrontal Cortex', 'Problem Solving', 'Seizures', 'Temporal Lobe... | 18,339,478 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F03.615.250'], ['C10.228.140.490.375.290'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.141.493'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Secukinumab attenuates reactive astrogliosis via IL-17RA/(C/EBPâ)/SIRT1 pathway in a rat model of germinal matrix hemorrhage. | AIMS: Reactive astrogliosis plays a critical role in neurological deficits after germinal matrix hemorrhage (GMH). It has been reported that interleukin-17A and IL-17A receptor IL-17RA/(C/EBPâ)/SIRT1 signaling pathway enhances reactive astrogliosis after brain injuries. We evaluated the effects of secukinumab on reacti... | ['Administration, Intranasal', 'Animals', 'Animals, Newborn', 'Antibodies, Monoclonal, Humanized', 'Astrocytes', 'Cerebral Hemorrhage', 'Disease Models, Animal', 'Female', 'Gliosis', 'Male', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Interleukin-17', 'Signal Transduction', 'Sirtuin 1'] | 31,020,769 | [['E02.319.267.120.655.500'], ['B01.050'], ['B01.050.050.282'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['A08.637.200', 'A11.650.200'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['C22.232', 'E05.598.500', 'E05.599.395.08... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of bacterial products on human ciliary function in vitro. | Ciliary activity protects the respiratory tract against inhaled particles, including bacteria, by transporting them trapped in mucus towards the pharynx. We have studied the effect of bacteria (Haemophilus influenzae, Staphylococcus aureus, and Pseudomonas aeruginosa) on human nasal cilia, measuring their in vitro cili... | ['Cilia', 'Haemophilus influenzae', 'Humans', 'In Vitro Techniques', 'Nasal Mucosa', 'Photometry', 'Pseudomonas aeruginosa', 'Sputum', 'Staphylococcus aureus'] | 3,919,460 | [['A11.284.180.165'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['E05.196.712'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['A12.200.808'], ['B03.300.390.400.800.750.100',... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postnatal electrical and morphological abnormalities in lumbar motoneurons from transgenic mouse models of amyotrophic lateral sclerosis. | Antidromically identified lumbar motoneurons intracellularly recorded in the entire brainstem/spinal cord preparation isolated from SOD1(G85R) postnatal mice (P3-P10) were labelled with neurobiotin and fully reconstructed in 3D from serial sections in order to analyse their morphology. This staining procedure revealed ... | ['Action Potentials', 'Amyotrophic Lateral Sclerosis', 'Animals', 'Animals, Newborn', 'Biotin', 'Cell Differentiation', 'Cell Polarity', 'Cell Shape', 'Dendrites', 'Disease Models, Animal', 'Humans', 'Lumbosacral Region', 'Mice', 'Mice, Transgenic', 'Motor Neurons', 'Nerve Degeneration', 'Organ Culture Techniques', 'Ri... | 18,075,124 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['B01.050.050.282'], ['D03.383.129.308.080', 'D08.211.096'], ['G04.152'], ['G04.250'], ['G04.320'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'],... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monoclonal antibodies against an epitope common to desmin and some keratins. | Hybridomas between spleen cells from autoimmune MRL/n mice and Sp2/0-Ag 14 myeloma cell line, are obtained by electric field-mediated fusion. A monoclonal antibody directed against a common antigenic determinant of desmin and some keratins has been obtained and characterized. | ['Animals', 'Antibodies, Monoclonal', 'Cattle', 'Desmin', 'Epitopes', 'Fluorescent Antibody Technique', 'Haplorhini', 'Humans', 'Keratins', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred Strains', 'Organ Specificity', 'Species Specificity'] | 2,448,236 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.593.200', 'D12.776.220.475.200'], ['D23.050.550'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.55... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combining anticancer agents photodynamic therapy and LCL85 leads to distinct changes in the sphingolipid profile, autophagy, caspase-3 activation in the absence of cell death, and long-term sensitization. | Two anticancer agents, LCL85 and photodynamic therapy (PDT) were combined to test whether the combination PDT/LCL85 evokes changes in the sphingolipid (SL) profile and promotes cell death. Treatment of SCCVII mouse squamous carcinoma cells using the silicone phthalocyanine Pc 4 for PDT induced increases in the prodeath... | ['Animals', 'Antineoplastic Agents', 'Autophagy', 'Carcinoma, Squamous Cell', 'Caspase 3', 'Cell Line, Tumor', 'Ceramides', 'Head and Neck Neoplasms', 'Humans', 'Indoles', 'Lysophospholipids', 'Mice', 'Photochemotherapy', 'Photosensitizing Agents', 'Propanolamines', 'Pyridinium Compounds', 'Sphingolipids', 'Sphingosine... | 21,545,791 | [['B01.050'], ['D27.505.954.248'], ['G04.011'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.065.313', 'D09.400.410.420.525.200',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure and stability of human hemoglobin microparticles prepared with a double emulsion technique. | Hemoglobin solutions can be used as blood substitutes but they present some disadvantages often due to their rapid removal from the bloodstream after injection. A possible way of overcoming this problem is to trap hemoglobin inside particles. This study deals with the preparation, structure and stability of poly(lactic... | ['Drug Compounding', 'Emulsions', 'Hemoglobins', 'Humans', 'Molecular Structure', 'Particle Size'] | 9,285,047 | [['E05.916.270'], ['D20.280.260', 'D26.255.165.260'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['G02.712']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polarization effects on oceanographic lidar. | A simplified radiative transfer equation yields a simple analytic expression for the co- and cross-polarized return in a linearly polarized oceanographic lidar. This equation agrees well with the lidar data over a wide range of oceanographic conditions. The relationship between depolarization and lidar attenuation show... | ['Computer Simulation', 'Lasers', 'Models, Theoretical', 'Oceans and Seas', 'Radar', 'Refractometry', 'Rivers'] | 18,542,194 | [['L01.224.160'], ['E07.632.490', 'E07.710.520'], ['E05.599'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['L01.178.847.500'], ['E05.196.808', 'H01.671.617.755'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Near infrared spectroscopy: experience on esophageal atresia infants. | OBJECTIVE: Near infrared spectroscopy (NIRS) gradually became the gold standard to guide anesthetic conduction during cardiac surgery, and nowadays, it is commonly utilized to monitor cerebral oxygenation during invasive procedures. Preterm babies also benefit from this non-invasive monitoring to prevent neurological s... | ['Brain', 'Carbon Dioxide', 'Esophageal Atresia', 'Female', 'Hemodynamics', 'Humans', 'Infant, Newborn', 'Intraoperative Care', 'Kidney', 'Male', 'Monitoring, Physiologic', 'Oxygen', 'Oxygen Consumption', 'Partial Pressure', 'Pilot Projects', 'Prospective Studies', 'Spectroscopy, Near-Infrared'] | 24,952,789 | [['A08.186.211'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['C06.198.330', 'C06.405.117.260', 'C16.131.314.330'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['A05.810.453'], ['E01.370.520'], ['D01.268.185.55... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enough's enough: conversations with myself and other practitioners. | Amidst considerable media focus on the stresses and strains on health services personnel who choose to leave the service, the author interviewed child mental health colleagues about how they coped with organizational stress in the UK National Health Service (NHS). The themes that emerged suggest that clinical staff fee... | ['Attitude of Health Personnel', 'Burnout, Professional', 'Child', 'Child Psychiatry', 'Cognitive Dissonance', 'Conflict, Psychological', 'Delivery of Health Care', 'Humans', 'Interdisciplinary Communication', 'Job Satisfaction', 'Organizational Culture', 'Organizational Policy', 'Psychology, Child', 'State Medicine', ... | 19,759,067 | [['F01.100.050', 'N05.300.100'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['M01.060.406'], ['F04.096.544.193', 'H02.403.690.130'], ['F02.463.188.305'], ['F01.658.209'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'], ['F0... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Frequency of deletion 508 among Irish cystic fibrosis patients. | We estimate the incidence of cystic fibrosis in Ireland to be at least 1 case per 1838 live births. We have analysed DNA from 44 Irish CF patients for the presence of deletion 508, using the polymerase chain reaction. The deletion was found in 76% of their chromosomes, and approximately 58% of the patients are homozygo... | ['Chromosome Deletion', 'Cystic Fibrosis', 'Gene Frequency', 'Humans', 'Ireland', 'Polymerase Chain Reaction'] | 2,210,748 | [['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['G05.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.467', 'Z01.639.587'], ['E05.393.6... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Dual silencing of the EGF and type 1 IGF receptors suggests dominance of IGF signaling in human breast cancer cells. | Signaling via the type 1 insulin-like growth factor receptor (IGF1R) confers resistance to EGF receptor (EGFR) inhibitors. It is plausible that reciprocal EGFR compensation could mediate resistance to IGF1R inhibition, prompting us to investigate effects of IGF1R depletion on EGFR signaling in breast cancer cells expre... | ['Breast Neoplasms', 'Cell Line, Tumor', 'ErbB Receptors', 'Extracellular Signal-Regulated MAP Kinases', 'Humans', 'MAP Kinase Kinase 4', 'Phosphorylation', 'RNA, Small Interfering', 'Receptor, IGF Type 1', 'STAT5 Transcription Factor', 'Signal Transduction', 'Somatomedins'] | 17,320,820 | [['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.81... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activity of ciprofloxacin against resistant clinical isolates. | The in-vitro activity of ciprofloxacin, a new quinolone derivative, was determined by broth microdilution for 518 clinical isolates. The MICs for 90% of the organisms were 2 mg/l for Pseudomonas aeruginosa, 8 mg/l for P. maltophilia, 4 mg/l for other Pseudomonas spp., 1 mg/l for Acinetobacter anitratus, 0.03-0.5 mg/l f... | ['Bacteria', 'Bacterial Infections', 'Cefotaxime', 'Ceftazidime', 'Ciprofloxacin', 'Drug Resistance, Microbial', 'Enterobacteriaceae', 'Gentamicins', 'Humans', 'Microbial Sensitivity Tests', 'Norfloxacin', 'Quinolines'] | 2,939,048 | [['B03'], ['C01.150.252'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['D03.633.100.810.835.322.186'], ['G06.225', 'G07.690.773.984.269'], ['B03.440.450.425', 'B03.660.250.150'], ['... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On the neural implausibility of the modular mind: Evidence for distributed construction dissolves boundaries between perception, cognition, and emotion. | Firestone & Scholl (F&S) rely on three problematic assumptions about the mind (modularity, reflexiveness, and context-insensitivity) to argue cognition does not fundamentally influence perception. We highlight evidence indicating that perception, cognition, and emotion are constructed through overlapping, distributed b... | ['Brain', 'Cognition', 'Emotions', 'Humans', 'Perception'] | 28,355,867 | [['A08.186.211'], ['F02.463.188'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593']] | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The impact of underreported Veterans Affairs data on national cancer statistics: analysis using population-based SEER registries. | Reduced cancer reporting by the US Department of Veterans Affairs (VA) hospitals in 2007 (for patients diagnosed through 2005) impacted the most recent US cancer surveillance data. To quantify the impact of the reduced VA reporting on cancer incidence and trends produced by the Surveillance, Epidemiology, and End Resul... | ['Adult', 'African Americans', 'Age Distribution', 'Aged', 'Confounding Factors, Epidemiologic', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Neoplasms', 'SEER Program', 'Sex Distribution', 'United States', 'Veterans'] | 19,318,639 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['N05.715.350.240', 'N06.850.490.718'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.52... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Floral-dip transformation of Arabidopsis thaliana to examine pTSO2::beta-glucuronidase reporter gene expression. | The ability to introduce foreign genes into an organism is the foundation for modern biology and biotechnology. In the model flowering plant Arabidopsis thaliana, the floral-dip transformation method has replaced all previous methods because of its simplicity, efficiency, and low cost. Specifically, shoots of young flo... | ['Arabidopsis', 'Arabidopsis Proteins', 'Flowers', 'Gene Expression', 'Genes, Reporter', 'Glucuronidase', 'Plants, Genetically Modified', 'Promoter Regions, Genetic', 'Ribonucleotide Reductases', 'Transformation, Genetic'] | 20,548,285 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['A18.024.249.500'], ['G05.297'], ['G05.360.340.024.340.435'], ['D08.811.277.450.426'], ['B01.650.520', 'B05.620.600'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['D08.811.682.810'], ['G05.728.865']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Familial cutaneous collagenoma: genetic studies on a family. | Familial cutaneous collagenoma is an inherited condition characterized by the presence of multiple dermal nodules symmetrically distributed on the trunk and upper arms. In this study, six patients, the proband, his four siblings and a niece, representing a kindred of fifty-two subjects, were examined for aymptomatic cu... | ['Adolescent', 'Adult', 'Collagen Diseases', 'Female', 'Humans', 'Male', 'Pedigree', 'Pregnancy', 'Pregnancy Complications', 'Skin', 'Skin Diseases'] | 486,326 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A retrospective cohort study of factors that affect healing in long-term care residents with chronic wounds. | Chronic ulcers such as pressure, ischemic, and venous ulcers are common in long-term care (LTC) and frequently do not heal. A retrospective medical records review of all LTC residents referred to a wound consultative service between April 1999 and January 2007 was conducted to assess predictors of 6-month healing outco... | ['Aged', 'Chronic Disease', 'Cohort Studies', 'Comorbidity', 'Diabetes Complications', 'Female', 'Hemoglobins', 'Humans', 'Leg Ulcer', 'Logistic Models', 'Male', 'Minnesota', 'Multivariate Analysis', 'Nursing Homes', 'Peripheral Vascular Diseases', 'Predictive Value of Tests', 'Pressure Ulcer', 'Prognosis', 'Retrospect... | 19,174,587 | [['M01.060.116.100'], ['C23.550.291.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['C19.246.099'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.893.592'], ['E05.318.740.500.525', 'E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Expression of leptin and long form of leptin receptors messenger ribonucleic acid and protein in endometrium of patients with polycystic ovary syndrome]. | OBJECTIVE: To study the expression of leptin and long form of leptin receptors (Ob-R(L)) messenger ribonucleic acid (mRNA) and protein in endometrium during mid-luteal phase of patients with polycystic ovary syndrome (PCOS).METHODS: The expression of leptin and Ob-R(L) mRNA in endometrium during mid-luteal phase from 1... | ['Adult', 'Endometrium', 'Female', 'Humans', 'Leptin', 'Polycystic Ovary Syndrome', 'RNA, Messenger', 'Receptors, Cell Surface', 'Receptors, Leptin'] | 12,921,548 | [['M01.060.116'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['C04.182.612.765', 'C13.351.500.056.630.580.765', 'C19.391.630.580.765'], ['D13.444.735.544'], ['D12.776.543.750']... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The protective action of melatonin on indomethacin-induced gastric and testicular oxidative stress in rats. | Reactive oxygen species and lipid peroxidation play a role in the pathogenesis induced by the non-steroidal anti-inflammatory drug indomethacin. Melatonin (MLT) protection against indomethacin-induced oxidative tissue injury was investigated in gastric mucosa and testis of rats. MLT was administered intragastrically (i... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antioxidants', 'Cytosol', 'Gastric Mucosa', 'Hydroxyl Radical', 'Indomethacin', 'Isoenzymes', 'L-Lactate Dehydrogenase', 'Lipid Peroxidation', 'Lipoxygenase', 'Male', 'Melatonin', 'Mitochondria', 'Oxidation-Reduction', 'Oxidative Stress', 'Rats', 'Superoxide Dismu... | 11,523,592 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D01.045.250.357', 'D01.248.497.158.459.300'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Socio-economic aspects of Gum Arabic production in Dalanj area, South Korodofan, Sudan. | Acacia senegal (locally: Hashab tree) is one of the most important tree species in Sudan as it considers the main Gum Arabic producing tree. The objective of this study is to investigate the socio-economic aspects of gum Arabic production and to assess contribution of gum Arabic to sustainable livelihood of local peopl... | ['Acacia', 'Agriculture', 'Gum Arabic', 'Seasons', 'Social Class', 'Sudan', 'Surveys and Questionnaires'] | 24,511,757 | [['B01.650.940.800.575.912.250.401.025'], ['J01.040'], ['D05.750.078.739.500', 'D09.698.700.500', 'D20.215.721.249.500'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['I01.880.853.996.755', 'N01.824.782'], ['Z01.058.290.120.760'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.98... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Reversal of methylprednisolone effects in allergen-exposed female BALB/c mice. | A high percentage of asthma is associated with aeroallergen exposures. Glucocorticoids such as methylprednisolone represent a major method for managing chronic asthma. However, studies suggested that corticosteroid therapy might have the potential to stimulate rather than inhibit adaptive immune inflammatory reactions,... | ['Administration, Intranasal', 'Allergens', 'Animals', 'Asthma', 'Bronchoalveolar Lavage Fluid', 'Cyclosporine', 'Disease Models, Animal', 'Drug Antagonism', 'Female', 'Glucocorticoids', 'Immunosuppressive Agents', 'Injections, Intraperitoneal', 'Lung', 'Methacholine Chloride', 'Methylprednisolone', 'Mice', 'Mice, Inbr... | 20,391,114 | [['E02.319.267.120.655.500'], ['D23.050.063'], ['B01.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.927.100.500'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.968.310'], ['D06.472.040.543', 'D27.505.696.399.472.488'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Statins Are Underutilized in Patients with Nonalcoholic Fatty Liver Disease and Dyslipidemia. | BACKGROUND: Cardiovascular disease provides the greatest mortality risk in patients with nonalcoholic fatty liver disease (NAFLD). Clinical practice guidelines recommend statins to treat dyslipidemia in patients with NAFLD; however, the extent to which such patients receive statins has not been studied.METHODS: We cond... | ['Adult', 'Aged', 'Aged, 80 and over', 'Dyslipidemias', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Inappropriate Prescribing', 'Male', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Odds Ratio', 'Young Adult'] | 26,707,137 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C18.452.584.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['E02.319.490', 'N02.421.450.500.249'], ['M01.060.116.630'], ['C06.552.241.519'], ['E05.318.740.600... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Perioperative deaths: a comparative study of coroner's autopsies between the periods of 1989-1991 and 1992-1994. | An earlier retrospective, clinicopathological review of 132 perioperative Coroner's autopsies (excluding cases of preoperative major trauma), conducted by the Department of Forensic Medicine during the period from January 1989 to December 1991, showed that such cases accounted for an average of 2% of all Coroner's auto... | ['Aged', 'Aged, 80 and over', 'Autopsy', 'Cause of Death', 'Coroners and Medical Examiners', 'Female', 'Humans', 'Iatrogenic Disease', 'Jurisprudence', 'Male', 'Middle Aged', 'Retrospective Studies', 'Surgical Procedures, Operative'] | 8,893,920 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.526.485.230', 'N02.360.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.875'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Phylogeny of caucasian rock lizards (Darevskia) and other true lizards based on mitogenome analysis: Optimisation of the algorithms and gene selection. | We generated a phylogeny for Caucasian rock lizards (Darevskia), and included six other families of true lizards (Lacertini), based on complete mitochondrial genome analysis. Next-generation sequencing (NGS) of genomic DNA was used to obtain 16 new mitogenomes of Darevskia. These, along with 35 sequences downloaded fro... | ['Algorithms', 'Animals', 'DNA, Mitochondrial', 'Genome, Mitochondrial', 'High-Throughput Nucleotide Sequencing', 'Lizards', 'Models, Genetic', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA'] | 32,511,235 | [['G17.035', 'L01.224.050'], ['B01.050'], ['D13.444.308.283.225'], ['G05.360.340.360'], ['E05.393.760.319'], ['B01.050.150.900.833.393'], ['E05.599.395.397'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['E05.393.760.700']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Outdoor air pollution and emergency department visits for asthma among children and adults: a case-crossover study in northern Alberta, Canada. | BACKGROUND: Recent studies have observed positive associations between outdoor air pollution and emergency department (ED) visits for asthma. However, few have examined the possible confounding influence of aeroallergens, or reported findings among very young children.METHODS: A time stratified case-crossover design wa... | ['Adolescent', 'Adult', 'Aged', 'Air Pollutants', 'Alberta', 'Allergens', 'Asthma', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Confounding Factors, Epidemiologic', 'Cross-Over Studies', 'Emergency Service, Hospital', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nitrogen Dioxide', 'Odds Ratio', 'Seasons'] | 18,157,917 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.888.284.101'], ['Z01.107.567.176.064'], ['D23.050.063'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Justicidin A inhibits the transport of tumor necrosis factor-alpha to cell surface in lipopolysaccharide-stimulated RAW 264.7 macrophages. | Exposure of macrophages to lipopolysaccharide (LPS) induces release of tumor necrosis factor-alpha (TNF-alpha), which is initially synthesized as a 26-kDa pro-TNF-alpha followed by proteolytic processing to a 17-kDa secreted form. In this study, justicidin A, an arylnaphthalide lignan isolated from Justicia procumbens,... | ['Animals', 'Biological Transport', 'Cell Line', 'Dioxolanes', 'Drug Interactions', 'Gene Expression', 'Interleukin-6', 'Lignans', 'Lipopolysaccharides', 'Macrophages', 'Mice', 'RNA, Messenger', 'Tumor Necrosis Factor-alpha'] | 15,102,934 | [['B01.050'], ['G03.143'], ['A11.251.210'], ['D03.383.246.238'], ['G07.690.773.968'], ['G05.297'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D02.455.426.559.389.140.450'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A11.329.372', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Localized nodular synovitis of the temporomandibular joint. A case report. | A case of localized nodular synovitis of the temporomandibular joint is described and discussed. There are no cases previously reported in the literature. The distinction between synovitis of the villo-nodular type and that of the localized nodular type can be made, given the close collaboration of clinician and pathol... | ['Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged', 'Synovitis', 'Synovitis, Pigmented Villonodular', 'Temporomandibular Joint'] | 282,394 | [['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.870'], ['C04.557.450.565.380.690.500', 'C05.550.870.445.500', 'C05.651.869.762.500'], ['A02.835.583.861', 'A14.907']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transient restoration of succinate dehydrogenase activity after rhabdomyolysis in iron-sulphur cluster deficiency myopathy. | Myopathy with exercise intolerance and deficiency of iron-sulphur cluster proteins is caused by an intronic IVS5+382 G>C mutation in ISCU, the gene encoding the iron-sulphur cluster assembly protein (IscU). The mutation causes alternative splicing resulting in a truncated protein and severely reduced levels of IscU pro... | ['Aged', 'Biopsy', 'Deficiency Diseases', 'Female', 'Humans', 'Introns', 'Iron-Sulfur Proteins', 'Muscle, Skeletal', 'Muscular Diseases', 'Mutation', 'Rhabdomyolysis', 'Succinate Dehydrogenase'] | 21,196,119 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C18.654.521.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['D12.776.157.427.374.375... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bed capacities and disinfection practices in hospitals in Istanbul are correlated. | BACKGROUND: Disinfection, antisepsis and sterilization (DAS) practices are of critical importance in hospital practice. This study aims to investigate the daily DAS practices of private hospitals in Istanbul, Turkey.METHODS: The DAS practices of 155 private hospitals in Istanbul province were investigated using a quest... | ['Antisepsis', 'Disinfection', 'Hospital Bed Capacity', 'Hospitals, Private', 'Humans', 'Surveys and Questionnaires', 'Turkey'] | 25,885,540 | [['N06.850.780.200.450.150'], ['N06.850.780.200.450.850.375'], ['N02.278.306.472'], ['N02.278.421.481'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.252.245.500.850']] | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Urban and suburban malaria in Rond?nia (Brazilian Western Amazon) II. Perennial transmissions with high anopheline densities are associated with human environmental changes. | Longitudinal entomological surveys were performed in Vila Candel?ria and adjacent rural locality of Bate Estaca concomitantly with a clinical epidemiologic malaria survey. Vila Candel?ria is a riverside periurban neighborhood of Porto Velho, capital of the state of Rond?nia in the Brazilian Amazon. High anopheline dens... | ['Animals', 'Anopheles', 'Brazil', 'Female', 'Humans', 'Insect Vectors', 'Longitudinal Studies', 'Malaria, Falciparum', 'Malaria, Vivax', 'Population Density', 'Population Dynamics', 'Population Surveillance', 'Seasons', 'Suburban Population', 'Urban Population'] | 17,568,931 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['Z01.107.757.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C01.610.752.530.650', 'C01... | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Proposal and Validation of a Knee Measurement System for Patients With Osteoarthritis. | OBJECTIVE: Currently most measurements of knee joint function are obtained through observation and patient-reported outcomes. This paper proposes an implementation and validation of a knee monitor to measure quantitative joint data in multiple degrees of freedom. The proposed system is configurable with minimal patient... | ['Accelerometry', 'Equipment Design', 'Humans', 'Knee Joint', 'Mobile Applications', 'Models, Biological', 'Osteoarthritis, Knee', 'Range of Motion, Articular', 'Robotics', 'Wearable Electronic Devices'] | 29,993,529 | [['E05.003'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['L01.224.900.685'], ['E05.599.395'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E01.370.600.700', 'G11.427.760'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['E07.305.906']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Decreases in regional cerebral blood flow with normal aging. | Positron emission tomographic (PET) images of regional cerebral blood flow (rCBF) from 30 normal, resting volunteers aged 30 to 85 years were analysed to identify areas where rCBF fell with age. Images were anatomically normalised, and a pixel-by-pixel linear regression was performed to remove differences in global CBF... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Blood Flow Velocity', 'Cerebrovascular Circulation', 'Female', 'Frontal Lobe', 'Gyrus Cinguli', 'Hippocampus', 'Humans', 'Male', 'Middle Aged', 'Parietal Lobe', 'Temporal Lobe', 'Tomography, Emission-Computed'] | 2,050,757 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.159'], ['A08.186.211.200.885.287.500.270'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[EFFICACY OF WELDING TECHNOLOGY AS A PRINCIPAL METHOD OF DISSECTION AND HEMOSTASIS IN ENDOCRINAL SURGERY]. | Today in the clinic all surgical interventions on endocrinal organs are conducted, using welding technology. Comparative analysis of the operative interventions efficacy, performed applying a standard method (control group) and using welding technology (the main group), was conducted. Performance of operations, using e... | ['Analgesics', 'Blood Loss, Surgical', 'Electrocoagulation', 'Endocrine Glands', 'Endocrine Surgical Procedures', 'Endocrine System Diseases', 'Hemostatic Techniques', 'Humans', 'Operative Time', 'Pain, Postoperative', 'Treatment Outcome'] | 26,591,864 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['C23.550.414.300', 'C23.550.505.300'], ['E02.154.402', 'E04.014.170.402'], ['A06.300'], ['E04.270'], ['C19'], ['E02.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['C23.550.767.700', 'C23.888.592.612.832'], ['... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Echocardiographic predictors of symptomatic patent ductus arteriosus in extremely-low-birth-weight preterm neonates. | OBJECTIVE: Identify echocardiographic parameters at <or=4 day postnatal that predict the subsequent need for closure of a clinically significant patent ductus arteriosus (sPDA) in extremely-low-birth-weight neonates (ELBW).STUDY DESIGN: Serial echocardiograms obtained in 115 ELBW at <or=10 day postnatal were examined t... | ['Ductus Arteriosus, Patent', 'Gestational Age', 'Humans', 'Infant, Extremely Low Birth Weight', 'Infant, Newborn', 'Male', 'Predictive Value of Tests', 'Regional Blood Flow', 'Retrospective Studies', 'Severity of Illness Index', 'Ultrasonography'] | 20,182,434 | [['C14.240.400.340', 'C14.280.400.340', 'C16.131.240.400.340'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460.600.500'], ['M01.060.703.520'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['G09.330.100.780'], ['E05.318... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes. | G protein-coupled receptors (GPCRs) are established drug targets. Despite their considerable appeal as targets for next-generation anthelmintics, poor understanding of their diversity and function in parasitic helminths has thwarted progress towards GPCR-targeted anti-parasite drugs. This study facilitates GPCR researc... | ['Acetylcholine', 'Animals', 'Evolution, Molecular', 'Fasciola hepatica', 'Genome, Helminth', 'Humans', 'Neuropeptides', 'Octopamine', 'Phylogeny', 'Platyhelminths', 'Receptors, G-Protein-Coupled', 'Rhodopsin', 'Sequence Alignment', 'Sequence Analysis, RNA', 'Serotonin'] | 29,474,932 | [['D02.092.211.111'], ['B01.050'], ['G05.045.250', 'G16.075.250'], ['B01.050.500.500.736.715.408.380.420'], ['G05.360.340.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.400', 'D12.776.631.650'], ['D02.033.100.291.525', 'D02.092.063.291.525', 'D02.092.211.215.811.651', 'D02.092.471.683.725'], ['G05.69... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Prognostic significance of serum anti-Epstein-Barr virus antibodies in nasopharyngeal carcinoma]. | OBJECTIVE: This study was aimed to investigate the association between serum against Epstein-Barr virus (EBV) antibodies levels and nasopharyngeal carcinoma (NPC) patients' prognosis.METHODS: Blood samples from 140 primary NPC patients without metastasis were collected before and after treatment. The titers of VCA/IgA ... | ['Adolescent', 'Adult', 'Aged', 'Antibodies, Viral', 'Antigens, Viral', 'Capsid Proteins', 'Carcinoma', 'Child', 'Female', 'Herpesvirus 4, Human', 'Humans', 'Immunoglobulin A', 'Male', 'Middle Aged', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Prognosis'] | 24,044,217 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.327'], ['D12.776.964.970.600.550'], ['C04.557.470.200'], ['M01.060.406'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Workers' compensation: coverage, benefits, and costs, 1992-93. | Benefit payments under workers' compensation programs in the United States during 1992-93 stabilized in comparison with the experience of prior years, which had been marked by substantial growth. In 1992, the total benefit amount of $44.7 billion was 5.9 percent higher than the amount in 1991. The 1993 benefit amount o... | ['Costs and Cost Analysis', 'Employment', 'Humans', 'Insurance, Health, Reimbursement', 'United States', "Workers' Compensation"] | 7,482,131 | [['N03.219.151'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.480', 'N03.219.521.710'], ['Z01.107.567.875'], ['N03.219.521.346.866', 'N03.219.521.576.300.900']] | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Phytochemical and antitrypanosomal investigation of the fractions and compounds isolated from Artemisia elegantissima. | CONTEXT: Trypanosoma brucei brucei (T.b. brucei) infection causes death in cattle, while the current treatments have serious toxicity problems. However, natural products can be used to overcome the problems associated with parasitic diseases including T.b. brucei.OBJECTIVE: Artemisia elegantissima Pamp (Asteraceae) was... | ['Animals', 'Artemisia', 'Phytochemicals', 'Plant Components, Aerial', 'Plant Extracts', 'Sheep', 'Trypanocidal Agents', 'Trypanosoma brucei brucei'] | 24,597,622 | [['B01.050'], ['B01.650.940.800.575.912.250.100.100'], ['D23.704'], ['A18.024'], ['D20.215.784.500', 'D26.667'], ['B01.050.150.900.649.313.500.380.791'], ['D27.505.954.122.250.100.875'], ['B01.268.475.868.887.080']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Incidence of intestinal pathogens in asylum applicants]. | UNLABELLED: In Mecklenburg-Vorpommern the Provincial Government has decreed that the laboratory diagnostic examination of applicants for asylum is limited to Salmonella and Shigella. A comprehensive bacteriological and parasitological investigation of 517 applicants for asylum showed a wide pattern of intestinal pathog... | ['Cross-Sectional Studies', 'Dysentery, Bacillary', 'Emigration and Immigration', 'Germany', 'Humans', 'Incidence', 'Intestinal Diseases, Parasitic', 'Mass Screening', 'Refugees', 'Risk Factors', 'Salmonella Infections'] | 7,620,249 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.52... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Functional outcomes of motor vehicle crash thoracic injuries in pediatric and adult occupants. | OBJECTIVE: Characterization of the severity of injury should account for both mortality and disability. The objective of this study was to develop a disability metric for thoracic injuries in motor vehicle crashes (MVCs) and compare the functional outcomes between the pediatric and adult populations.METHODS: Disability... | ['Abbreviated Injury Scale', 'Accidents, Traffic', 'Adolescent', 'Adult', 'Aged', 'Child', 'Databases, Factual', 'Disabled Persons', 'Female', 'Fractures, Bone', 'Humans', 'Male', 'Middle Aged', 'Motor Vehicles', 'Risk Factors', 'Thoracic Injuries'] | 29,185,785 | [['E05.318.308.940.968.875.125', 'E05.944.250', 'N04.452.859.564.800.125', 'N05.715.360.300.715.500.800.100'], ['N06.850.135.392'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['M01.150'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Superior semicircular canal dehiscence in relation to the superior petrosal sinus: a potential cause of pulsatile tinnitus. | AIM: To examine the association between superior semicircular canal dehiscence (SSCD) and pulsatile tinnitus (PT).MATERIALS AND METHODS: Two SSCD groups included 408 unilateral persistent PT patients, and 511 controls undergoing head and neck dual-phase contrast-enhanced computed tomography (DP-CECT) for reasons other ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Contrast Media', 'Female', 'Humans', 'Iopamidol', 'Labyrinth Diseases', 'Male', 'Middle Aged', 'Prevalence', 'Semicircular Canals', 'Tinnitus', 'Tomography, X-Ray Computed'] | 26,072,165 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.100.400.880.410', 'D02.455.426.559.389.127.375.880.410'], ['C09.218.568'], ['M01.060.116.630'], ['E05.318.308.985.525.750',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stability studies on maize leaf phosphoenolpyruvate carboxylase: the effect of salts. | The solution stability of phosphoenolpyruvate carboxylase (PEPC) has been determined in the presence of various salts by temperature-accelerated enzyme inactivation and also by using high-performance size-exclusion chromatography. Kosmotropic (water structuring) anions in the Hofmeister series (HPO(4)2-, citrate3-, SO(... | ['Chromatography, High Pressure Liquid', 'Enzyme Stability', 'Hydrogen-Ion Concentration', 'Indicators and Reagents', 'Phosphoenolpyruvate Carboxylase', 'Plant Leaves', 'Salts', 'Temperature', 'Zea mays'] | 7,819,239 | [['E05.196.181.400.300'], ['E05.916.360', 'G02.111.700.500'], ['G02.300'], ['D27.720.470.410'], ['D08.811.520.224.125.650'], ['A18.024.812'], ['D01.786'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['B01.650.940.800.575.912.250.822.966']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Management of anuric intensive-care patients with arteriovenous hemofiltration. | It may be concluded from our results to date, that arteriovenous hemofiltration is an accurate and reliable method for the management of fluid balance in patients resistant to diuretics. Early use of this method may improve the prognosis of intensive-care patients by decongestion or dehydration of lungs, reduction of c... | ['Adolescent', 'Adult', 'Aged', 'Anuria', 'Arteriovenous Shunt, Surgical', 'Blood', 'Blood Flow Velocity', 'Blood Pressure', 'Child, Preschool', 'Critical Care', 'Female', 'Heparin', 'Humans', 'Male', 'Middle Aged', 'Ultrafiltration', 'Water-Electrolyte Imbalance'] | 7,409,920 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C12.777.419.078', 'C12.777.934.141', 'C13.351.968.419.078', 'C13.351.968.934.070'], ['E04.035.087', 'E04.100.814.868.249'], ['A12.207.152', 'A15.145'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['M01.060.406.448'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Giant hepatic hemangioma--diagnostic value of radioisotope investigations]. | In an example of a 60-year-old female patients with a giant hepatic haemangioma the authors discuss the diagnostic possibilities of radioisotope angiography in the detection of this vascular pathology. In confrontation with ultrasonographic examinations, computerized tomography, laparoscopy and even coeliac angiography... | ['Female', 'Hemangioma', 'Humans', 'Liver Neoplasms', 'Middle Aged', 'Radionuclide Imaging', 'Technetium'] | 2,633,496 | [['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E01.370.350.710', 'E01.370.384.730'], ['D01.268.271.870', 'D01.268.556.843', 'D01.268.956.875', 'D01.496.749.305.870', 'D01.552.544.843']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Co-assembly of HPV capsid proteins and aggregation-induced emission fluorogens for improved cell imaging. | In order to improve the cell-imaging ability, and particularly, to extend the bio-application of AIEgen, human papillomavirus (HPV) capsid protein L1 was assembled with the complex of DNA and aggregation-induced emission fluorogen 9,10-distyrylhydrazine (DSAI), where the virus-like particles (VLPs) of HPV encapsulate t... | ['Capsid Proteins', 'DNA', 'Fluorescent Dyes', 'HEK293 Cells', 'HeLa Cells', 'Humans', 'Hydrazines', 'Microscopy, Confocal', 'Nanoparticles', 'Oncogene Proteins, Viral', 'Particle Size'] | 32,091,054 | [['D12.776.964.970.600.550'], ['D13.444.308'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442'], ['E01.370.350.515.395', 'E05.595.395'], ['J01.637.512.600'],... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Accuracy of determining small renal mass management with risk stratified biopsies: confirmation by final pathology. | PURPOSE: We assess the accuracy of a biopsy directed treatment algorithm in correctly assigning active surveillance vs treatment in patients with small renal masses by comparing biopsy results with final surgical pathology.MATERIALS AND METHODS: From 1999 to 2011, 151 patients with small renal masses 4 cm or smaller un... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biopsy, Needle', 'Carcinoma, Renal Cell', 'Humans', 'Kidney Neoplasms', 'Middle Aged', 'Reproducibility of Results', 'Retrospective Studies', 'Risk Assessment', 'Young Adult'] | 23,253,955 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Alimentary trigger factors that provoke migraine and tension-type headache]. | Based on a review of the literature the authors discuss the role of nutrition in the precipitation of migraine and tension-type headache (TTH). The available information relies largely on the subjective assessment of the patients. Controlled trials suggest that alcohol and caffeine withdrawal are the most important nut... | ['Cacao', 'Caffeine', 'Dehydration', 'Digestive System Diseases', 'Humans', 'Migraine Disorders', 'Substance Withdrawal Syndrome', 'Tension-Type Headache'] | 15,806,385 | [['B01.650.940.800.575.912.250.859.821.500.164'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['C18.452.950.179', 'C23.550.274'], ['C06'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.546.399.750'], ['C25.775.835', 'F03.900.825'], ['C10.228.140.546.399.875']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mild and efficient DBU-catalyzed amidation of cyanoacetates. | A mild, high-yielding, and practical protocol for the direct amidation of alkyl cyanoacetates using DBU is presented. This method eliminates the need for activation of cyanoacetic acid and/or high temperatures. It has been applied to the large-scale synthesis of CP-690,550-10 (1), a compound under development for the t... | ['Acetates', 'Amides', 'Bridged Bicyclo Compounds, Heterocyclic', 'Catalysis', 'Combinatorial Chemistry Techniques', 'Immunosuppressive Agents', 'Molecular Structure', 'Piperazines', 'Pyrimidines', 'Pyrroles'] | 19,341,310 | [['D02.241.081.018', 'D10.251.400.045'], ['D02.065'], ['D03.605.084'], ['G02.130'], ['E05.197.312', 'J01.897.836.249.249'], ['D27.505.696.477.656'], ['G02.111.570', 'G02.466'], ['D03.383.606'], ['D03.383.742'], ['D03.383.129.578']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Exercise reveals impairments in left ventricular systolic function in patients with metabolic syndrome. | Metabolic syndrome (MetS) is the manifestation of a cluster of cardiovascular risk factors and is associated with a threefold increase in the risk of cardiovascular morbidity and mortality, which is suggested to be mediated, in part, by resting left ventricular (LV) systolic dysfunction. However, to what extent resting... | ['Diastole', 'Exercise', 'Exercise Tolerance', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Systole', 'Ultrasonography', 'Ventricular Dysfunction, Left', 'Ventricular Function, Left'] | 24,036,595 | [['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['G11.427.410.698.277', 'I03.350'], ['G11.427.680.270'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['G09.330.580.880', 'G11.427.494.570.880'], ['E01.370.350.850'],... | ['Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Thyroid dysfunctions in children detected in mass screening for congenital hypothyroidism. | BACKGROUND: Congenital hypothyroidism (CH) affects approximately 1:3000-1:4000 infants.OBJECTIVES: To determine the prevalence of CH and isolated hyperthyrotropinemia (IHT) in newborns selected in mass screening for CH.METHODS: Mass screening of 233,120 neonates born in southeastern Poland was carried out and CH-suspec... | ['Congenital Hypothyroidism', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Neonatal Screening', 'Poland', 'Thyroid Function Tests', 'Thyroid Gland', 'Thyrotropin'] | 21,648,281 | [['C05.116.099.343.347', 'C05.116.132.256', 'C16.320.240.625', 'C19.297.155', 'C19.874.482.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.910', 'E01.370.500.580', 'E05.200.910', 'E05.318.308.980.438.580.580', 'N02.421.726.233.443.816', 'N05.715.360.300.800.438.500.575', 'N06.... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cryptosporidiosis outbreak in captive chelonians (Testudo hermanni) with identification of two Cryptosporidium genotypes. | An outbreak of diarrhea in an outdoor group of captive Hermann's tortoises (Testudo hermanni) was associated with fecal shedding of cryptosporidial oocysts, as determined by coproscopic and immunoassay examinations. With partial sequencing of the 18S ribosomal RNA gene, 2 different Cryptosporidium genotypes could be id... | ['Animals', 'Base Sequence', 'Cryptosporidiosis', 'Cryptosporidium', 'DNA, Protozoan', 'Diarrhea', 'Disease Outbreaks', 'Feces', 'Immunoenzyme Techniques', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'RNA, Ribosomal, 18S', 'Sequence Alignment', 'Turtles'] | 22,529,132 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C01.610.432.269', 'C01.610.701.688.235', 'C01.610.752.250.269', 'C01.610.752.625.235', 'C06.405.469.452.269', 'C22.674.710.235'], ['B01.043.075.189.250.150.160'], ['D13.444.308.442'], ['C23.888.821.214'], ['N06.850.290'], ['A12.459'], ['E05.478.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The effects of glutamine-supplemented parenteral nutrition in premature infants. | BACKGROUND: Glutamine (GLN) is the primary fuel for rapidly dividing cells, yet it is not a constituent of parenteral nutritional formulas administered to newborns. The aims of this prospective, randomized, double-blind trial were (1) to confirm the safety of glutamine supplementation for premature infants and (2) to e... | ['Birth Weight', 'Blood Urea Nitrogen', 'Double-Blind Method', 'Female', 'Gestational Age', 'Glutamic Acid', 'Glutamine', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Parenteral Nutrition, Total', 'Prospective Studies'] | 8,788,268 | [['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G07.345.500.325.235... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Affinity of estradiol mustard for estrogen receptors and its enzymatic degradation in uterine and breast cancer cytosols. | Estradiol mustard (EM) is the 3,17beta-diester of estradiol-17beta (E2) with the nitrogen mustard derivative chlorphenacyl. The ability of EM to bind to cytoplasmic estrogen receptors was tested by inhibition of the binding of 3H-E2 to rat uterine cytosol at 18 degrees C and 30 degrees C. At both temperatures an inhibi... | ['Animals', 'Binding Sites', 'Breast Neoplasms', 'Cytosol', 'Estradiol', 'Female', 'Humans', 'Mustard Compounds', 'Rats', 'Receptors, Estrogen', 'Time Factors', 'Uterine Neoplasms'] | 992,905 | [['B01.050'], ['G02.111.570.120'], ['C04.588.180', 'C17.800.090.500'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.728'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid hierarchical assembly of medium-size DNA cassettes. | Synthetic biology applications call for efficient methods to generate large gene cassettes that encode complex gene circuits in order to avoid simultaneous delivery of multiple plasmids encoding individual genes. Multiple methods have been proposed to achieve this goal. Here, we describe a novel protocol that allows on... | ['Cloning, Molecular', 'DNA', 'DNA-Directed DNA Polymerase', 'Genes', 'Polymerase Chain Reaction'] | 22,422,837 | [['E05.393.220'], ['D13.444.308'], ['D08.811.913.696.445.308.300'], ['G05.360.340.024.340'], ['E05.393.620.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human oviductal fluid proteins. V. Identification of human oviductin-I as alpha-fetoprotein. | OBJECTIVE: To investigate whether human oviductin-I (hOV-I) from human oviductal fluid (hOF) and human alpha-fetoprotein (hAFP) are identical molecules.DESIGN: Comparison of amino acid and carbohydrate composition of hOV-I with that of hAFP. Isolation of hAFP from oviductal fluid of a patient and evaluation of its immu... | ['Animals', 'Blotting, Western', 'Body Fluids', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Fallopian Tubes', 'Female', 'Glycoproteins', 'Humans', 'Proteins', 'Radioimmunoassay', 'Serum Albumin', 'alpha-Fetoproteins'] | 7,678,232 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A12.207'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A05.360.319.114.373', 'A13.706.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Concentration of lactate concentration in experimental glial tumors and brain tissue during brief artificial hyperglycemia]. | The authors studied the content of lactic acid in glial tumors of the brain and brain tissue of rats in short-term artificial hyperglycemia. In short-term artificial glycemia the lactic acid content in glial tumors of animals was almost twice the level of this metabolite in the brain tissue, which is due to the high po... | ['Animals', 'Astrocytoma', 'Blood Glucose', 'Brain Chemistry', 'Brain Neoplasms', 'Female', 'Glucose', 'Glycolysis', 'Hyperglycemia', 'Lactates', 'Lactic Acid', 'Rats'] | 4,002,955 | [['B01.050'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['D09.947.875.359.448.500'], ['G02.111.150', 'G03.185'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D09.947.875.359.448'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['C1... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparing administrative and survey data for ascertaining cases of irritable bowel syndrome: a population-based investigation. | BACKGROUND: Administrative and survey data are two key data sources for population-based research about chronic disease. The objectives of this methodological paper are to: (1) estimate agreement between the two data sources for irritable bowel syndrome (IBS) and compare the results to those for inflammatory bowel dise... | ['Adult', 'Aged', 'Cohort Studies', 'Data Interpretation, Statistical', 'Female', 'Health Surveys', 'Humans', 'Irritable Bowel Syndrome', 'Male', 'Manitoba', 'Middle Aged', 'Prevalence', 'Retrospective Studies', 'Socioeconomic Factors', 'Urban Population'] | 20,113,531 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Hepatocellular carcinoma complicating autoimmune hepatitis: role of hepatitis C virus. | The risk of hepatocellular carcinoma in autoimmune hepatitis is low, even in patients with long-standing cirrhosis. Because of the increasing recognition of an association of hepatitis C virus (HCV) with autoimmune hepatitis, at least in some geographical areas, and with hepatocellular carcinoma (HCC) (hepatoma), we ha... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Autoimmune Diseases', 'Base Sequence', 'Blood', 'Carcinoma, Hepatocellular', 'Female', 'Hepacivirus', 'Hepatitis', 'Hepatitis Antibodies', 'Humans', 'Liver', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Molecular Probes', 'Molecular Sequence Data', 'RNA, Viral'] | 7,657,274 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C20.111'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A12.207.152', 'A15.145'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['B04.450.380', 'B04.820.578.344.475'], ['C06.552... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Clinical laboratory's trends in the 21st century]. | The new century presents numerous challenges and opportunities for the clinical laboratory scientists. Japan's economic recession has affected health care system directly. Clinical laboratories in particular have been hard hit financially. Laboratory people have striven for financial efficiency and balance within their... | ['Blood Glucose', 'Clinical Laboratory Techniques', 'Costs and Cost Analysis', 'Forecasting', 'Humans', 'Reagent Kits, Diagnostic', 'Reference Standards'] | 11,769,556 | [['D09.947.875.359.448.500'], ['E01.370.225', 'E05.200'], ['N03.219.151'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['E05.978.808']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Selective versus non-selective antiarrhythmic approach for prevention of atrial fibrillation after coronary surgery: is there a need for pre-operative risk stratification? A prospective placebo-controlled study using low-dose sotalol. | AIM: This study evaluated the advantages of 'selective' over 'non-selective' antiarrhythmic prevention of atrial fibrillation after coronary surgery based on a new risk prediction algorithm.METHODS AND RESULTS: In a retrospective analysis of a prospective randomized trial, a model for risk prediction was determined bas... | ['Adult', 'Aged', 'Algorithms', 'Anti-Arrhythmia Agents', 'Atrial Fibrillation', 'Coronary Artery Bypass', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Risk Assessment', 'Sotalol'] | 9,717,015 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['D27.505.954.411.097'], ['C14.280.067.198', 'C23.550.073.198'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.44... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Inactivation of human and simian rotaviruses by chlorine dioxide. | The inactivation of single-particle stocks of human (type 2, Wa) and simian (SA-11) rotaviruses by chlorine dioxide was investigated. Experiments were conducted at 4 degrees C in a standard phosphate-carbonate buffer. Both virus types were rapidly inactivated, within 20 s under alkaline conditions, when chlorine dioxid... | ['Animals', 'Chlorine', 'Chlorine Compounds', 'Disinfectants', 'Haplorhini', 'Humans', 'Hydrogen-Ion Concentration', 'Oxides', 'Rotavirus'] | 2,160,222 | [['B01.050'], ['D01.268.380.150', 'D01.362.225'], ['D01.210'], ['D27.505.954.122.425', 'D27.720.274'], ['B01.050.150.900.649.313.988.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D01.248.497.158.685', 'D01.650.550'], ['B04.820.223.719.790']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Values of Hematological Indicators in the Screening of á-Thalassemia in Fujian Area of China]. | OBJECTIVE: To analyze the genotypes and the hematological phenotypic characteristics of á-thalassemia in different areas of Fujian and to evaluate the values of mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), hemoglobin (Hb), RBC distribution width/red blood cell (RDW/RBC) for screening á-thalassemia ... | ['China', 'Erythrocyte Indices', 'Female', 'Genotype', 'Humans', 'Male', 'Mass Screening', 'alpha-Thalassemia'] | 30,738,464 | [['Z01.252.474.164'], ['E01.370.225.625.230', 'E05.200.625.230', 'G09.188.260'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['C15.378.071.141.150.875.100... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Foreign body in the airway: unusual cause of acute dyspnoe after cardiac surgery. | We report on a 68-year-old male who presented with acute onset of dyspnoea and cough. After coronary artery bypass grafting and mitral valve repair with an annuloplasty ring, postoperative recovery was initially uneventful. On the 6th postoperative day, he came back to intensive care unit due to acute dyspnoea. Fig. 1 ... | ['Acute Disease', 'Aged', 'Coronary Artery Bypass', 'Dental Prosthesis', 'Diagnosis, Differential', 'Dyspnea', 'Foreign-Body Migration', 'Humans', 'Male', 'Radiography'] | 15,940,436 | [['C23.550.291.125'], ['M01.060.116.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E06.780.346', 'E07.695.190'], ['E01.171'], ['C08.618.326', 'C23.888.852.371'], ['C26.392.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vegetative reproduction capacities of floodplain willows--cutting response to competition and biomass loss. | While several studies on regeneration in Salicaceae have focused on seedling recruitment, little is known about factors controlling their vegetative reproduction. In two greenhouse experiments, we studied the response of floodplain willows (Salix fragilis, S. viminalis, S. triandra) to competition with Poa trivialis, a... | ['Biomass', 'Ecology', 'Plant Roots', 'Plant Shoots', 'Reproduction', 'Salix', 'Soil', 'Trees', 'Water'] | 21,972,956 | [['G16.500.275.157.100', 'N06.230.124.100'], ['H01.158.273.248', 'H01.277.249'], ['A18.400'], ['A18.024.875'], ['G08.686.784'], ['B01.650.940.800.575.912.250.859.797.875.833'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.650.915'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Increased Variance in Oral and Gastric Microbiome Correlates With Esophagectomy Anastomotic Leak. | BACKGROUND: Anastomotic leak after esophagectomy remains a significant source of morbidity and mortality. The gastrointestinal (GI) microbiome has been found to play a significant role in tumor oncogenesis and postoperative bowel anastomotic leak. We hypothesized that the GI microbiome could differentiate between esoph... | ['Adenocarcinoma', 'Aged', 'Anastomotic Leak', 'Carcinoma, Squamous Cell', 'Esophageal Mucosa', 'Esophageal Neoplasms', 'Esophagectomy', 'Female', 'Gastric Mucosa', 'Gastrointestinal Microbiome', 'Humans', 'Male', 'Middle Aged', 'Mouth', 'Prospective Studies'] | 29,307,454 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C23.550.767.071'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A03.556.875.500.180', 'A10.615.550.146'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.346'], ['A03.556.875.875.440', 'A10.615.550.291']... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The GATA factor AreA regulates localization and in vivo binding site occupancy of the nitrate activator NirA. | The GATA factor AreA is a wide-domain regulator in Aspergillus nidulans with transcriptional activation and chromatin remodelling functions. AreA interacts with the nitrate-specific Zn(2)-C(6) cluster protein NirA and both proteins cooperate to synergistically activate nitrate-responsive genes. We have previously estab... | ['Aspergillus nidulans', 'Base Sequence', 'Binding Sites', 'Blotting, Northern', 'DNA Footprinting', 'DNA Primers', 'Fungal Proteins', 'Plasmids', 'Transcription Factors'] | 16,390,440 | [['B01.300.381.081.420'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.393.300'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D12.776.354'], ['G05.360.600'], ['D12.776.930']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ovarian gene transcription and effect of cadmium pre-exposure during artificial sexual maturation of the European eel (Anguilla anguilla). | European eels are dangerously threatened with extinction. Recent advances tend to show that pollution could, in addition to other already identified factors, contribute to this drama. In a previous report, cadmium (Cd) pre-exposure was found to strongly stimulate the pituitary-liver-gonad axis of maturing female silver... | ['Anguilla', 'Animals', 'Cadmium', 'Catalase', 'Environmental Exposure', 'Europe', 'Female', 'Fish Proteins', 'Gene Expression', 'Metallothionein', 'Oocytes', 'Ovary', 'RNA, Messenger', 'Sexual Maturation', 'Transcription, Genetic', 'Up-Regulation', 'Water Pollutants, Chemical'] | 19,484,408 | [['B01.050.150.900.493.338.282'], ['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D08.811.682.732.332'], ['N06.850.460.350'], ['Z01.542'], ['D12.776.325'], ['G05.297'], ['D12.776.556.670'], ['A05.360.490.690.680', 'A11.497.497.600'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Risk factors and costs associated with methicillin-resistant Staphylococcus aureus bloodstream infections. | OBJECTIVES: To compare the cost of hospitalization of patients with methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI) versus patients with methicillin-sensitive S. aureus (MSSA) BSI, controlling for severity of underlying illness; and to identify risk factors associated with MRSA BSI.DESIGN... | ['Aged', 'Case-Control Studies', 'Cost of Illness', 'Female', 'Humans', 'Male', 'Methicillin Resistance', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Washington'] | 15,188,850 | [['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The phorbol 12-myristate 13-acetate (PMA)-induced oxidative burst in rat peritoneal neutrophils is increased by a 0.1 mT (60 Hz) magnetic field. | Magnetic fields (MF) may affect biological systems by increasing free radical concentrations. To test this, we have investigated whether low frequency (60 Hz) low intensity (0.1 mT) MF can modulate the phorbol 12-myristate 13- acetate (PMA) induced respiratory burst in primed rat peritoneal neutrophils, followed in rea... | ['Animals', 'Electromagnetic Fields', 'Male', 'Neutrophils', 'Peritoneal Cavity', 'Rats', 'Rats, Sprague-Dawley', 'Reactive Oxygen Species', 'Respiratory Burst', 'Tetradecanoylphorbol Acetate'] | 7,498,533 | [['B01.050'], ['G01.358.500.260', 'G01.358.750.500'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['A01.923.047.025.600.678'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D01.339.431',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microtubule disrupting agent-mediated inhibition of cancer cell growth is associated with blockade of autophagic flux and simultaneous induction of apoptosis. | OBJECTIVES: Given that autophagy inhibition is a feasible way to enhance sensitivity of cancer cells towards chemotherapeutic agents, identifying potent autophagy inhibitor has obvious clinical relevance. Here, we investigated ability of TN-16, a microtubule disrupting agent, on modulation of autophagic flux and its si... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Autophagy', 'Cell Line, Tumor', 'Cell Proliferation', 'Female', 'Humans', 'Mice', 'Mice, Nude', 'Microtubules', 'Neoplasms', 'Pyrrolidinones', 'Tubulin Modulators'] | 32,167,212 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['G04.011'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['A11.284.430.214.190.75... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential representation of auditory categories between cell classes in primate auditory cortex. | A comprehensive understanding of the neural mechanisms of cognitive function requires an understanding of how neural representations are transformed across different scales of neural organization: from within local microcircuits to across different brain areas. However, the neural transformations within the local micro... | ['Acoustic Stimulation', 'Action Potentials', 'Animals', 'Auditory Cortex', 'Interneurons', 'Macaca mulatta', 'Male', 'Pyramidal Cells'] | 22,570,374 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['A08.675.358', 'A11.671.358'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['A08.675.790', 'A11.671.790']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Repeat operations on the biliary tract in a district hospital]. | An experience with 79 reoperations in 68 patients who had been subjected to operations for acute and chronic cholecystitis enabled the author to conclude that retained calculi in bile ducts were the main cause of reoperations. The amount of repeated surgical interventions and postoperative lethality can be decreased by... | ['Adult', 'Aged', 'Biliary Tract Surgical Procedures', 'Cholecystitis', 'Cholelithiasis', 'Female', 'Hospitals, District', 'Hospitals, Public', 'Humans', 'Intraoperative Complications', 'Male', 'Middle Aged', 'Postoperative Complications', 'Reoperation', 'Russia'] | 2,939,615 | [['M01.060.116'], ['M01.060.116.100'], ['E04.210.120'], ['C06.130.564.263'], ['C06.130.409'], ['N02.278.421.510.140'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505'], ['M01.060.116.630'], ['C23.550.767'], ['E04.690'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Modification of orientation sensitivity of cat visual cortex neurons by removal of GABA-mediated inhibition. | The effects of an inhibitor of GABA synthesis, 3-mercaptopropionic acid (MP), and of the GABA antagonist bicuculline (BIC), on the direction and orientation sensitivity of visual cortical neurons were investigated using a computer-controlled stimulus presentation system. Intravenous administration of MP, which was usua... | ['3-Mercaptopropionic Acid', 'Animals', 'Bicuculline', 'Cats', 'Dose-Response Relationship, Drug', 'Electroencephalography', 'GABA Antagonists', 'Neural Inhibition', 'Neurons', 'Orientation', 'Seizures', 'Synapses', 'Visual Cortex', 'gamma-Aminobutyric Acid'] | 421,752 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mica: a convenient support for biological SEM specimens in a TEMSCAN microscope. | Mica is proposed as a convenient substrate for SEM specimens. Mechanically, mica is rigid and can be cut, punched and cleaved into suitable sizes. Compared to glass substrates, mice seems to be more charge 'resistant' when irradiated with the same beam density in the microscope. | ['Aluminum Silicates', 'Microscopy, Electron, Scanning', 'Specimen Handling'] | 6,655,687 | [['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.225.998', 'E05.200.998']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of methods for assessing hypothalamic-pituitary-adrenal (HPA) axis activity in asthma patients treated with inhaled corticosteroids. | Suppression of the hypothalamic-pituitary-adrenal (HPA) axis is an accepted indicator of potential side effects from inhaled corticosteroids. Although cortisol monitoring is frequently used to detect changes in HPA axis activity, the optimal method for identifying the subset of asthma patients on inhaled steroids who e... | ['Administration, Inhalation', 'Adrenocorticotropic Hormone', 'Adult', 'Analysis of Variance', 'Androstadienes', 'Anti-Inflammatory Agents', 'Area Under Curve', 'Asthma', 'Female', 'Fluocinolone Acetonide', 'Fluticasone', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Male', 'Nebulizers and Vaporizers',... | 11,865,969 | [['E02.319.267.050'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D04.210.500.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Target-guided screening of fragments (TGSOF) in the discovery of inhibitors against EV-A71 3C protease. | Target-guided screening of fragments (TGSOF) was developed and employed in the identification of EV-A71 3C protease (3Cpro) inhibitors. We identified 4-acetylpyridine and 3-acetylpyridine as effective P3 fragments of an inhibitor and obtained the corresponding irreversible inhibitors 12c and 12fvia this method. Further... | ['Cysteine Endopeptidases', 'Dose-Response Relationship, Drug', 'Drug Discovery', 'Enterovirus A, Human', 'Molecular Structure', 'Protease Inhibitors', 'Pyridines', 'Structure-Activity Relationship', 'Viral Proteins'] | 29,497,732 | [['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['B04.820.578.750.284.180'], ['G02.111.570', 'G02.466'], ['D27.505.519.389.745'], ['D03.383.725'], ['G02.111.830', 'G07.690.773.997'], ['D12.776.964']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Recannulation of Distal Radial Artery for Staged Procedure After Successful Primary Percutaneous Coronary Intervention. | There are limited data regarding the snuffbox approach. Our experience highlights the feasibility of snuffbox approach as the access route for primary PCI and recannulation of distal radial artery for staged PCI. | ['Aged', 'Arterial Occlusive Diseases', 'Catheterization, Peripheral', 'Coronary Angiography', 'Humans', 'Male', 'Percutaneous Coronary Intervention', 'Radial Artery', 'ST Elevation Myocardial Infarction', 'Vascular Surgical Procedures'] | 30,279,299 | [['M01.060.116.100'], ['C14.907.137'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.100.814.529.968', 'E04.502.382.968'], ['A07.015.114.74... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Estimation of the left ventricular ejection fraction using a novel multiphase, dark-blood, breath-hold MR imaging technique. | OBJECTIVE: In this paper, we evaluate a recently proposed dual-phase dark-blood MR sequence for estimating the left ventricular ejection fraction, compare Simpson's method of estimation of ejection fraction with a model based on the biplane method, assess the reproducibility of both methods, and finally, test a semiaut... | ['Adult', 'Aged', 'Cardiomyopathies', 'Echocardiography', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Myocardial Infarction', 'Observer Variation', 'Reference Values', 'Reproducibility of Results', 'Stroke Volume', 'Ventricular Function, Left'] | 9,207,508 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.238'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['E01.354.75... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Toxicity to topical dimethyl sulfoxide (DMSO) when used as an extravasation antidote. | DMSO is a dipolar, aprotic, hygroscopic solvent for which a large number of pharmacologic properties have been claimed. Topical DMSO is considered an effective and safe antidote to be used with topical cooling after extravasations of vesicant drugs. A case of toxicity after its use as an antidote is described. Furtherm... | ['Administration, Topical', 'Adult', 'Antidotes', 'Dimethyl Sulfoxide', 'Extravasation of Diagnostic and Therapeutic Materials', 'Fatal Outcome', 'Humans', 'Male'] | 12,426,960 | [['E02.319.267.120'], ['M01.060.116'], ['D27.505.696.706.037', 'D27.720.799.037'], ['D02.886.640.150'], ['C23.550.340', 'C26.371'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Variations in Ixodes ricinus density and Borrelia infections associated with cattle introduced into a woodland in The Netherlands. | The effect of introduced large herbivores on the abundance of Ixodes ricinus ticks and their Borrelia infections was studied in a natural woodland in The Netherlands. Oak and pine plots, either ungrazed or grazed by cattle, were selected. Ticks were collected weekly by blanket dragging. Borrelia infections were determi... | ['Animals', 'Animals, Wild', 'Borrelia', 'Borrelia Infections', 'Cattle', 'DNA, Bacterial', 'Ixodes', 'Mice', 'Netherlands', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Population Density', 'Tick Infestations'] | 18,836,006 | [['B01.050'], ['B01.050.050.300'], ['B03.440.425.410.711.193', 'B03.851.595.193'], ['C01.150.252.400.794.352'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.212'], ['B01.050.500.131.166.132.832.400.425'], ['B01.050.150.900.649.313.992.635.505.500'], ['Z01.542.651'], ['E05.393.620.500'], ['G05.365.795.595'], [... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Variation of the folding and dynamics of the Escherichia coli chromosome with growth conditions. | We examine whether the Escherichia coli chromosome is folded into a self-adherent nucleoprotein complex, or alternately is a confined but otherwise unconstrained self-avoiding polymer. We address this through in vivo visualization, using an inducible GFP fusion to the nucleoid-associated protein Fis to non-specifically... | ['Cell Division', 'Chromosomes, Bacterial', 'Escherichia coli', 'Escherichia coli Proteins', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Microscopy, Fluorescence', 'Nucleoproteins', 'Recombinant Fusion Proteins', 'Staining and Labeling', 'Time-Lapse Imaging'] | 23,078,205 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.360.340.024.340.435'], ['D12.776.532.265'], ['E01.370.350.515.458', 'E05.595.458'], ['D12.776.664'], ['D12.776.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Metabolism of farnesyl diphosphate in tobacco BY-2 cells treated with squalestatin. | Plant isoprenoids represent a large group of compounds with a wide range of physiological functions. In the cytosol, isoprenoids are synthesized via the classical acetate/mevalonate pathway. In this pathway, farnesyl diphosphate (FPP) occupies a central position, from which isoprene units are dispatched to the differen... | ['Aphidicolin', 'Bridged Bicyclo Compounds, Heterocyclic', 'Carbon Radioisotopes', 'Cell Cycle', 'Cell Division', 'Cell Line', 'Coenzymes', 'Farnesol', 'Farnesyl-Diphosphate Farnesyltransferase', 'G1 Phase', 'Hydroxymethylglutaryl CoA Reductases', 'Mitochondria', 'Plants, Toxic', 'Polyisoprenyl Phosphates', 'Radioisoto... | 11,171,211 | [['D02.455.849.291.075'], ['D03.605.084'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['G04.144'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D08.211'], ['D02.033.415.400', 'D02.455.849.765.424', 'D10.289.400'], ['D08.811.913.225.431'], ['G04.144.500... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multivariate analysis of smoking and other risk factors for obstructive lung diseases and related symptoms. | Multivariate analyses of the relationship of risk factors and respiratory symptomatology in a longitudinal epidemiologic study of airways obstructive disease in a white community population has yielded some consistent findings. Diagnosed airway obstructive diseases and functional impairment appear to be related to a se... | ['Adolescent', 'Adult', 'Aged', 'Arizona', 'European Continental Ancestry Group', 'Humans', 'Longitudinal Studies', 'Lung Diseases, Obstructive', 'Middle Aged', 'Population Surveillance', 'Probability', 'Risk', 'Smoking', 'Spirometry', 'Surveys and Questionnaires'] | 7,107,807 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.875.760.100'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C08.381.495'], ['M01.060.116.630'], ['E05.318.308.980.438.700', 'N05.715... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Integrating non-university institutions into clinical research. The example of implementing the concept of quality of life into regional management of cancer patients]. | Implementation is the stepwise introduction of a concept with the goal to change the behaviour of health care providers. The concept of quality of life (QL) was implemented in order to improve the regional care for cancer patients. The following steps were taken: creating a quality circle, teaching the concept QL, list... | ['Academies and Institutes', 'Breast Neoplasms', 'Critical Pathways', 'Female', 'Germany', 'Health Services Research', 'Humans', 'Male', 'Neoplasms', 'Outcome and Process Assessment, Health Care', 'Patient Care Team', 'Quality of Life', 'Rectal Neoplasms'] | 11,824,367 | [['N03.540.052'], ['C04.588.180', 'C17.800.090.500'], ['N04.590.233.624.625', 'N04.590.275'], ['Z01.542.315'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['N04.761.559', 'N05.715.360.575'], ['N04.590.715'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400... | ['Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Endothelin alters the reactivity of vasa vasorum: mechanisms and implications for conduit vessel physiology and pathophysiology. | 1 The walls of certain large blood vessels are nourished by the vasa vasorum, a network of microvessels that penetrate the adventitia and media of the vessel wall. The purpose of this study was to characterize endothelin-1 (ET-1)-mediated contraction of vasa and to investigate whether threshold concentrations of ET-1 a... | ['Animals', 'Calcium', 'Calcium-Transporting ATPases', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Endothelin-1', 'Enzyme Inhibitors', 'Imidazoles', 'In Vitro Techniques', 'Indoles', 'Nickel', 'Norepinephrine', 'Oligopeptides', 'Piperidines', 'Potassium', 'Prostaglandin Endoperoxides, Synthetic', 'Swine', 'V... | 10,578,136 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968.477'], ['D12.644.276.400.225', 'D12.776.467.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The anti-atherogenic cytokine interleukin-33 inhibits the expression of a disintegrin and metalloproteinase with thrombospondin motifs-1, -4 and -5 in human macrophages: Requirement of extracellular signal-regulated kinase, c-Jun N-terminal kinase and phosphoinositide 3-kinase signaling pathways. | Atherosclerosis is an inflammatory disorder of the vasculature regulated by cytokines. Amongst the cytokines, IL-33 attenuates the development of atherosclerosis in mouse model systems via several mechanisms, including inhibition of macrophage foam cell formation and promotion of a Th1 to Th2 shift. Proteases produced ... | ['Animals', 'Atherosclerosis', 'Cytokines', 'Disintegrins', 'Extracellular Signal-Regulated MAP Kinases', 'Humans', 'Interleukins', 'JNK Mitogen-Activated Protein Kinases', 'Macrophages', 'Metalloproteases', 'Mice', 'Phosphatidylinositol 3-Kinases', 'Signal Transduction', 'Thrombospondins'] | 24,275,094 | [['B01.050'], ['C14.907.137.126.307'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.644.138'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['D08.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A gene for familial juvenile nephronophthisis (recessive medullary cystic kidney disease) maps to chromosome 2p. | Familial juvenile nephronophthisis (NPH) is a chronic autosomal recessive kidney disease responsible for 15% of end stage renal failure in children. NPH is frequently (16% of cases) associated with Leber amaurosis (termed Senior-L?ken syndrome, SLS). Linkage analyses, performed in 22 multiplex NPH families (18 without ... | ['Base Sequence', 'Child', 'Chromosome Mapping', 'Chromosomes, Human, Pair 2', 'Cloning, Molecular', 'DNA Primers', 'DNA, Satellite', 'Female', 'Genes, Recessive', 'Genetic Linkage', 'Humans', 'Kidney Diseases', 'Kidney Failure, Chronic', 'Lod Score', 'Male', 'Molecular Sequence Data', 'Pedigree', 'Polymerase Chain Rea... | 7,981,755 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.060.406'], ['E05.393.183'], ['A11.284.187.520.300.235.245', 'G05.360.162.520.300.235.245'], ['E05.393.220'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.36... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Impact of Disgust on Intentions to Undergo Colorectal Surgery. | BACKGROUND: Surgeons present patients with complex information at the perioperative appointment. Emotions likely play a role in surgical decision-making, and disgust is an emotion of revulsion at a stimulus that can lead to avoidance.OBJECTIVE: The purpose of this study was to determine the impact of disgust on intenti... | ['Adult', 'Colorectal Neoplasms', 'Colostomy', 'Cross-Sectional Studies', 'Decision Making', 'Disgust', 'Female', 'Humans', 'Intention', 'Male', 'Mental Recall', 'Middle Aged', 'Patient Acceptance of Health Care', 'Patient Education as Topic', 'Perioperative Period', 'Surveys and Questionnaires', 'United States'] | 30,312,221 | [['M01.060.116'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E04.210.338.225', 'E04.579.338.225'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['F01.470.307'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Framework to Evaluate Exposure Relevance and Data Needs for Risk Assessment of Nanomaterials using in Vitro Testing Strategies. | This article presents a multistage framework for evaluating the strength of evidence of nanomaterial (NM) exposure characterization data to optimize the utility of in vitro testing strategies for human health risk assessment. This framework is intended to aid risk assessors in evaluating the relevance of data from in v... | ['Humans', 'In Vitro Techniques', 'Nanostructures', 'Risk Assessment'] | 26,905,487 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['J01.637.512'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Workload in oral and maxillofacial surgery: analysis of time trends from linked statistics in a defined population. | Data from the Oxford Region were used to study trends in hospital admission rates and demographic profiles of hospital care in the National Health Service in oral and maxillofacial surgery. In a defined population of 1.9 million people, admission rates for inpatient care, day case care, and outpatient attendance rates ... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Ambulatory Surgical Procedures', 'Child', 'Child, Preschool', 'Dental Service, Hospital', 'Emergency Service, Hospital', 'England', 'Female', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Mouth Diseases', 'Orthodontics', 'Patient Admission', 'Pa... | 1,622,955 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.030'], ['M01.060.406'], ['M01.060.406.448'], ['N02.278.216.500.968.298', 'N02.421.240.200', 'N04.452.442.452.422.298'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336']... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression. | BACKGROUND: Chronic spinal cord injury (SCI) induces immune depression in patients, which contributes to their higher risk of developing infections. While defects in humoral immunity have been reported, complications in T-cell immunity during the chronic phase of SCI have not yet been explored.METHODS: To assess the im... | ['Animals', 'Apoptosis', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Calcium Ionophores', 'Cell Proliferation', 'Cytokines', 'Disease Models, Animal', 'Female', 'Ionomycin', 'Mice', 'Mice, Inbred C57BL', 'Norepinephrine', 'Programmed Cell Death 1 Receptor', 'Spinal Cord Injuries', 'Tetradecanoylphorbol... | 24,690,491 | [['B01.050'], ['G04.146.954.035'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D27.505.519.562.374.100', 'D27.720.395.100'], ['G04.161.750', 'G07.345.249.410.750'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hiatal hernia in pediatric gastroesophageal reflux. | BACKGROUND: This study compares esophageal pH-monitoring parameters of children with gastroesophageal reflux (GER) with or without hiatal hernia (HH) and determines the outcome of those with GER and HH.METHODS: Among 718 children with GER, 45 children (6%) with associated HH were retrospectively studied. They were divi... | ['Child', 'Child, Preschool', 'Esophagus', 'Female', 'Gastroesophageal Reflux', 'Hernia, Hiatal', 'Humans', 'Hydrogen-Ion Concentration', 'Infant', 'Infant, Newborn', 'Male', 'Monitoring, Physiologic', 'Nervous System Diseases', 'Retrospective Studies', 'Treatment Failure', 'Treatment Outcome'] | 11,740,228 | [['M01.060.406'], ['M01.060.406.448'], ['A03.556.875.500'], ['C06.405.117.119.500.484'], ['C23.300.707.960.500.467'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.520'], ['C10'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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