Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. | A mutant strain (65E12) of Pseudomonas aeruginosa that is unable to produce rhamnolipid biosurfactants and lacks rhamnosyltransferase activity was genetically complemented by using a P. aeruginosa PG201 wild-type gene library. A single complementing cosmid was isolated on the basis of surface tension measurements of su... | ['Alkanes', 'Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Cloning, Molecular', 'Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Genes, Regulator', 'Genetic Complementation Test', 'Glycolipids', 'Molecular Sequence Data', 'Mutation', 'Pancreatic Elastase', 'Pseudomonas a... | 8,144,472 | [['D02.455.326.146'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Expanding dynamic kinetic protocols: transaminase-catalyzed synthesis of á-substituted â-amino ester derivatives. | Several á-alkylated â-amino esters have been obtained via DKR processes employing a kit of transaminases and isopropylamine as an amino donor in aqueous medium under mild conditions. Thus, while acyclic á-alkyl-â-keto esters afforded excellent conversions and enantioselectivities, although usually low diastereoselectiv... | ['Amino Acids', 'Catalysis', 'Esters', 'Kinetics', 'Stereoisomerism', 'Transaminases'] | 24,107,855 | [['D12.125'], ['G02.130'], ['D02.241.400'], ['G01.374.661', 'G02.111.490'], ['G02.607.445.682'], ['D08.811.913.477.700']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Replication protein A directs loading of the DNA damage checkpoint clamp to 5'-DNA junctions. | The heterotrimeric checkpoint clamp comprises the Saccharomyces cerevisiae Rad17, Mec3, and Ddc1 subunits (Rad17/3/1, the 9-1-1 complex in humans). This DNA damage response factor is loaded onto DNA by the Rad24-RFC (replication factor C-like complex with Rad24) clamp loader and ATP. Although Rad24-RFC alone does not b... | ['Adenosine Triphosphatases', 'Cell Cycle Proteins', 'DNA Damage', 'DNA Helicases', 'DNA Repair Enzymes', 'DNA-Binding Proteins', 'Endonucleases', 'Intracellular Signaling Peptides and Proteins', 'Nuclear Proteins', 'Proliferating Cell Nuclear Antigen', 'Replication Protein A', 'Replication Protein C', 'Saccharomyces c... | 16,864,589 | [['D08.811.277.040.025'], ['D12.776.167'], ['G05.200'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D08.811.074'], ['D12.776.260'], ['D08.811.277.352.355'], ['D12.644.360', 'D12.776.476'], ['D12.776.660'], ['D12.776.660.740', 'D23.050.290.750', 'D23.101.140.600'], ['D12.776.260.700'], ['D08.811.277.040.013.500.43... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cysteamine effects on somatostatin, catecholamines, pineal NAT and melatonin in rats. | The thiol reagent cysteamine was administered to adult male rats with the aim of investigating its effect on different neural and pineal components. As expected, immunoreactive somatostatin decreased in the median eminence (ME) (p less than 0.05) and gastric antrum (p less than 0.05) after cysteamine; however, no signi... | ['Acetyltransferases', 'Animals', 'Catecholamines', 'Cysteamine', 'Hydroxyindoleacetic Acid', 'Hypothalamus', 'Male', 'Median Eminence', 'Melatonin', 'Osmolar Concentration', 'Pineal Gland', 'Pyloric Antrum', 'Radioimmunoassay', 'Rats', 'Rats, Inbred Strains', 'Serotonin', 'Somatostatin'] | 2,423,200 | [['D08.811.913.050.134'], ['B01.050'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['D02.092.471.562.369', 'D02.886.489.472.369'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['A06.688.178.750', 'A06.688.357.500', 'A08.186.211.180.497.352.435.249', 'A08.18... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High expression of FOXM1 critical for sustaining cell proliferation in mitochondrial DNA-less liver cancer cells. | The copy number of mitochondrial DNA (mtDNA) is decreased in most cancer types, including hepatocellular carcinoma (HCC), compared to normal counterparts. However, a decrease in mtDNA usually leads to defects in cell proliferation, which contradicts the robustness of cancer cell proliferation. In this study, we found t... | ['Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Cell Proliferation', 'Cells, Cultured', 'DNA Copy Number Variations', 'DNA, Mitochondrial', 'Forkhead Box Protein M1', 'Gene Expression Regulation, Neoplastic', 'Hepatocytes', 'Humans', 'Liver Neoplasms', 'Up-Regulation'] | 32,032,602 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['G05.365.795.297.500'], ['D13.444.308.283.225'], ['D12.776.260.950.249.063', 'D12.776.930.977.249.063'], ['G05.308.370'], ['A11.436.348... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lactoquinomycin B, a novel antibiotic. | Streptomyces tanashiensis IM8442T was found to produce lactoquinomycin B, a novel antibiotic, together with lactoquinomycin A. Lactoquinomycin B was purified, and the physico-chemical and biological characteristics were studied. Lactoquinomycin B, C24H27NO9, mp 149-152 degrees C (dec), FD-MS m/z 473 (M+), is a basic su... | ['Animals', 'Antibiotics, Antineoplastic', 'Bacteria', 'Cell Line', 'Humans', 'Leukemia L5178', 'Magnetic Resonance Spectroscopy', 'Mice', 'Microbial Sensitivity Tests', 'Naphthoquinones', 'Spectrophotometry, Infrared', 'Streptococcus'] | 3,753,965 | [['B01.050'], ['D27.505.954.248.106'], ['B03'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.372.602', 'C04.619.531.602'], ['E05.196.867.519'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D02.455.426.559.847.638.721', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel-dependent mechanisms. | BACKGROUND AND PURPOSE: The growing epidemic of obesity and metabolic diseases necessitates the development of novel strategies to prevent and treat such diseases. Current research suggests that browning of white adipose tissue (WAT) promotes energy expenditure to counter obesity. Recent research suggests that activati... | ['Adipose Tissue, Brown', 'Adipose Tissue, White', 'Animals', 'Capsaicin', 'Cells, Cultured', 'Diet, High-Fat', 'HEK293 Cells', 'Humans', 'Male', 'Mice', 'Mice, Knockout', 'Obesity', 'TRPV Cation Channels'] | 27,174,467 | [['A10.165.114.322'], ['A10.165.114.830'], ['B01.050'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['A11.251'], ['G07.203.650.240.267'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.15... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A dominant-hereditary variation of the Pena-Shokeir syndrome; a case report. | Four children with the Pena-Shokeir syndrome are described. Apart from the classical manifestations of the syndrome: camptodactyly, ankyloses, facial anomalies, pulmonary hypoplasia, all four children had an extremely rigid skin. Possibly this rigidness of unknown origin led in these cases to fetal akinesia, which seem... | ['Abnormalities, Multiple', 'Adult', 'Arthrogryposis', 'Female', 'Fetal Movement', 'Genes, Dominant', 'Humans', 'Hypospadias', 'Infant, Newborn', 'Lung', 'Male', 'Polyhydramnios', 'Pregnancy', 'Retrognathia', 'Skin Abnormalities', 'Syndrome', 'Ultrasonography'] | 2,070,954 | [['C16.131.077'], ['M01.060.116'], ['C05.550.150', 'C05.651.102', 'C05.660.077', 'C16.131.621.077'], ['G07.345.500.325.235.374', 'G08.686.784.170.157.374'], ['G05.360.340.024.340.240', 'G05.420.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494.400', 'C12.706.516', 'C13.351.875.466', 'C16.131.939.516... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The compactEASIE is a feasible training model for endoscopic novices: a prospective randomised trial. | BACKGROUND: The objective benefit of a training using the compact Erlangen Active Simulator for Interventional Endoscopy-simulator was demonstrated in two prospective educational trials (New York, France). The present study analysed whether endoscopic novices are able to reach a comparable level of endoscopic skills as... | ['Clinical Competence', 'Computer-Assisted Instruction', 'Education, Medical, Graduate', 'Endoscopes, Gastrointestinal', 'France', 'Gastroenterology', 'Hemostasis, Endoscopic', 'Humans', 'Models, Anatomic', 'New York', 'Prospective Studies', 'Students, Medical', 'Time Factors'] | 16,942,923 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.903.771.500.208'], ['I02.358.337.350', 'I02.358.399.350'], ['E07.230.220.260', 'E07.858.240.260'], ['Z01.542.286'], ['H02.403.429.405'], ['E02.520.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['Z... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Named Groups [M]',... | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
[Relationship between apolipoprotein H and lipid in stroke patients]. | OBJECTIVE: To study the correlation of serum apolipoprotein H (ApoH) with blood lipids and the relationship between ApoH and stroke.METHODS: The serum levels of ApoH of 33 patients with acute cerebral infarction (ACI), 18 patients with acute cerebral hemorrhage (ACH), 17 patients with cerebral apoplexy and family histo... | ['Aged', 'Brain Infarction', 'Cerebral Hemorrhage', 'Cholesterol', 'Female', 'Glycoproteins', 'Humans', 'Lipids', 'Lipoproteins, LDL', 'Male', 'Middle Aged', 'Stroke', 'beta 2-Glycoprotein I'] | 11,953,169 | [['M01.060.116.100'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Heparin binds 8 kDa gelsolin cross-â-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension. | Glycosaminoglycans (GAGs) are highly sulfated linear polysaccharides prevalent in the extracellular matrix, and they associate with virtually all amyloid deposits in vivo. GAGs accelerate the aggregation of many amyloidogenic peptides in vitro, but little mechanistic evidence is available to explain why. Herein, spectr... | ['Amyloid', 'Benzothiazoles', 'Chemical Phenomena', 'Circular Dichroism', 'Electrophoretic Mobility Shift Assay', 'Fluorescence Polarization', 'Fluorescent Dyes', 'Gelsolin', 'Glycosaminoglycans', 'Heparin', 'Humans', 'Kinetics', 'Microscopy, Atomic Force', 'Nuclear Magnetic Resonance, Biomolecular', 'Peptide Fragments... | 21,348,501 | [['D05.500.049', 'D12.776.049'], ['D03.383.129.708.089', 'D03.633.100.185'], ['G02'], ['E05.196.867.151'], ['E05.196.401.500'], ['E05.196.712.516.600.390'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D05.750.078.730.350', 'D12.644.360.372.437', 'D12.776.157.125.412.437', 'D12.776.220.525.350', 'D12.776.476.387.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concurrent involved-field radiotherapy and XELOX in gastric cancer patients with postoperative oligometastatic recurrence. | PURPOSE: The aim of this study was to retrospectively observe gastric adenocarcinoma patients with postoperative oligometastatic recurrence and investigated the effects of concurrent involved-field radiotherapy (RT) and XELOX on progression-free survival (PFS).PATIENTS AND METHODS: From 2008 to 2011, 246 patients under... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Capecitabine', 'Chemoradiotherapy', 'Deoxycytidine', 'Disease-Free Survival', 'Female', 'Fluorouracil', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Oxaloacetates', 'Retrospective Studies', 'Stomach Neoplasm... | 25,693,933 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of Clinical Outcomes According to the Definition of Slow Graft Function in Deceased Donor Kidney Transplantation. | BACKGROUND: Slow graft function (SGF) is considered to be an intermediate state between immediate graft function (IGF) and delayed graft function (DGF). However, the criteria of SGF is still arbitrary, and the clinical outcomes of SGF are not fully understood.METHODS: A total of 212 deceased donor kidney transplantatio... | ['Adult', 'Delayed Graft Function', 'Female', 'Glomerular Filtration Rate', 'Graft Survival', 'Humans', 'Kidney', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Time Factors', 'Treatment Outcome'] | 31,474,452 | [['M01.060.116'], ['C23.550.277'], ['E01.370.390.400.300', 'G08.852.357'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.060.116.630'], ['C23.550.767'], ['G01.910.857'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities. | The Drosophila gene vasa encodes a DEAD-box protein, which is localized during early oogenesis to the perinuclear region of the nurse cells and later to the pole plasm at the posterior end of the oocyte. Posterior localization of vasa protein depends upon the functions of four genes: capu, spir, osk and stau. We have f... | ['Adenosine Triphosphate', 'Animals', 'Autoradiography', 'Cytoplasm', 'DEAD-box RNA Helicases', 'Drosophila', 'Drosophila Proteins', 'Female', 'Immunohistochemistry', 'Microscopy, Immunoelectron', 'Morphogenesis', 'Mutagenesis, Site-Directed', 'Oocytes', 'Oogenesis', 'Point Mutation', 'RNA Helicases', 'RNA Nucleotidylt... | 8,026,330 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A11.284.430.214'], ['D08.811.913.696.445.735.720.249'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['E01.370.225.500.607.512', 'E01.370... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitus. | BACKGROUND: Small intestine video-capsule endoscopy examination in patients with diabetes mellitus may be incomplete due to delayed gastric emptying.AIM: To measure video-capsule endoscopy gastric and small bowel transit time and to assess the completeness of the examination in diabetes mellitus patients.METHODS: In th... | ['Capsule Endoscopy', 'Case-Control Studies', 'Diabetes Mellitus', 'Female', 'Gastrointestinal Transit', 'Humans', 'Intestine, Small', 'Male', 'Middle Aged', 'Observer Variation', 'Physical Examination'] | 17,433,797 | [['E01.370.388.250.250.250.140'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C18.452.394.750', 'C19.246'], ['E01.370.372.310', 'G10.261.360.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of the metabolic syndrome on high-sensitivity C reactive protein levels in patients with acute coronary syndrome. | OBJECTIVE: Underlying predisposition for a heightened inflammatory response is postulated as one of the mechanisms for elevated high-sensitivity C reactive protein (hs-CRP) levels in patients with acute coronary syndrome (ACS). It is unclear whether metabolic syndrome (MetS) may cause a predisposition for heightened hs... | ['Acute Coronary Syndrome', 'Aged', 'Biomarkers', 'Body Mass Index', 'C-Reactive Protein', 'Case-Control Studies', 'Cross-Sectional Studies', 'Female', 'Humans', 'Inflammation Mediators', 'Logistic Models', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Odds Ratio', 'Risk Assessment', 'Risk Factors', 'Troponin', 'Up-Reg... | 19,577,754 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116.100'], ['D23.101'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure-specific binding and photosensitized cleavage of branched DNA three-way junction complexes by cationic porphyrins. | The interactions of cationic porphyrins with DNA oligonucleotides that form branched, three-way junction complexes (TWJ) were investigated using native gel electrophoresis, absorption spectroscopy and photochemical probing using DNA sequencing techniques. Meso-tetra(para-N- trimethylaniliniumyl)porphine (TMAP), meso-te... | ['Amino Acid Sequence', 'Binding Sites', 'DNA', 'In Vitro Techniques', 'Models, Molecular', 'Molecular Sequence Data', 'Molecular Structure', 'Photochemistry', 'Photosensitizing Agents', 'Porphyrins'] | 8,041,806 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['D13.444.308'], ['E05.481'], ['E05.599.595'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['H01.181.529.711'], ['D27.505.954.444.600', 'D27.505.954.600.710'], ['D03.383.129.578.840.500', 'D03.633.400.909.500', 'D04.345.783.500', 'D23.767.727']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of Curculigoside on Memory Impairment and Bone Loss via Anti-Oxidative Character in APP/PS1 Mutated Transgenic Mice. | Alzheimer's disease (AD) and osteoporosis are two closely related multifactorial progressively degenerative diseases that predominantly affect aged people. These two diseases share many common risk factors, including old age, being female, smoking, excessive drinking, low estrogen, and vitamin D3 levels. Additionally, ... | ['Acid Phosphatase', 'Amyloid beta-Protein Precursor', 'Animals', 'Antioxidants', 'Benzoates', 'Biomechanical Phenomena', 'Bone Density', 'Bone Resorption', 'Brain', 'Femur', 'Glucosides', 'Interleukin-6', 'Isoenzymes', 'Memory Disorders', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Mutation', 'Presenilin-1', 'Spatial M... | 26,186,010 | [['D08.811.277.352.650.025'], ['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['G01.154.090', 'G01.374.089'], ['G11.427.100'], ['C05.116.264', 'G11.427.213.15... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Measuring device for routine intraoperaative morphological-functional estimation of the peripheral outflow and terminal flow channels during operations in peripheral vascular surgery]. | In 1975, Heinrich, F?rster and Oschartz developed the radioresistometry as a method of intraoperative assessment of the peripheral resistance. In this report the authors describe a full-electronic apparatus of their own construction making possible to introduce the above mentioned method into the routine clinical progr... | ['Angiography', 'Humans', 'Intraoperative Care', 'Vascular Resistance', 'Vascular Surgical Procedures'] | 6,641,230 | [['E01.370.350.700.060', 'E01.370.370.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['G09.330.380.921'], ['E04.100.814']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Antenatal imaging: does the postnatal impact justify the effort? | This review explores what is already understood about antenatal diagnosis of a variety of conditions,including Down syndrome, what progress has been made in this field, the role that imaging plays in the diagnostic pathway and the impact on management of pregnancies and the parental decision process. An overview of fut... | ['Abortion, Legal', 'Counseling', 'Cultural Characteristics', 'Decision Making', 'Diagnostic Imaging', 'Female', 'Fetal Diseases', 'Humans', 'Mass Screening', 'Patient Care Team', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Outcome', 'Prenatal Diagnosis', 'Ultrasonography, Prenatal'] | 21,229,350 | [['E04.520.050.055'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['F02.463.785.373'], ['E01.370.350'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Sexual intercourse and high-risk sexual behaviours among a national sample of urban adolescents in China. | BACKGROUND: To describe the characteristics of a population with high-risk sexual behaviours and associations between sexual intercourse, high-risk sexual behaviours and socio-demographic characteristics among Chinese urban adolescents.METHODS: In 2005, 109,754 students in grades 10-12 and 33,653 college students were ... | ['Adolescent', 'Adolescent Behavior', 'China', 'Coercion', 'Coitus', 'Data Collection', 'Female', 'Humans', 'Male', 'Risk-Taking', 'Unsafe Sex', 'Urban Population', 'Young Adult'] | 20,147,385 | [['M01.060.057'], ['F01.145.022'], ['Z01.252.474.164'], ['I01.880.604.316', 'I01.880.630.200'], ['F01.145.802.188', 'G08.686.784.041'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.722'], ['F01.145.802.987'], ['N01.600.900'], ['M01.060.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[A method for studying the three-dimensional structure of organs and tissue in pathology]. | A new technique of scanning electron microscopy for visualization of hidden cellular surfaces in organs and tissue has been developed. It employs the sample incubation in 30% potassium hydroxide and 96% alcohol mixed in equal amounts and dissociation until single cells appear in the solution, this being checked under p... | ['Animals', 'Cells', 'Ethanol', 'Humans', 'Hydroxides', 'Microscopy, Electron, Scanning', 'Microscopy, Phase-Contrast', 'Potassium', 'Potassium Compounds'] | 1,596,189 | [['B01.050'], ['A11'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.045.250', 'D01.248.497.158.459'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.350.515.513.569', 'E05.490.630.569', 'E05.595.513.569'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650']... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of intensive endurance exercise on DNA damage in leucocytes. | OBJECTIVE: It has been shown that highly intensive anaerobic exercise induces DNA damage in leucocytes (LEU). The present study was designed to investigate whether intensive endurance exercise is capable of inducing comparable effects.EXPERIMENTAL DESIGN: A prospective study.PARTICIPANTS: Twelve men (aged 27.3 +/- 4.1 ... | ['Adult', 'DNA Damage', 'Exercise', 'Humans', 'Leukocytes', 'Male', 'Neutrophil Activation', 'Physical Endurance', 'Prospective Studies'] | 9,763,795 | [['M01.060.116'], ['G05.200'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['G12.604'], ['G11.427.680', 'I03.450.642.845.054.600'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Does the combination of erythropoietin and tapered oral corticosteroids improve recovery following iatrogenic nerve injury? | INTRODUCTION: The reported prognosis for recovery after peripheral nerve injury is remarkably poor. Deficits may persist for years, resulting in significant functional disability. Both corticosteroids and Erythropoietin have been investigated as neuroprotective agents; however, their efficacy in total hip and knee arth... | ['Adrenal Cortex Hormones', 'Adult', 'Aged', 'Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Erythropoietin', 'Female', 'Humans', 'Iatrogenic Disease', 'Intraoperative Complications', 'Male', 'Middle Aged', 'Peripheral Nerve Injuries', 'Prognosis', 'Recovery of Function', 'Retrospective Studies', ... | 27,287,740 | [['D06.472.040'], ['M01.060.116'], ['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Peripheral Monocyte Count Predicts Outcomes in Patients with Acute Ischemic Stroke Treated with rtPA Thrombolysis. | The aim of this study was to investigate the predictive value of the monocyte count as a prognostic biomarker on 90 days in patients with acute ischemic stroke (AIS) treated with recombinant tissue plasminogen activator (rtPA) thrombolysis. In total, 206 patients with AIS treated in our institute between 2013 and 2018 ... | ['Aged', 'Brain Ischemia', 'Female', 'Follow-Up Studies', 'Humans', 'Leukocyte Count', 'Leukocytes, Mononuclear', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Recombinant Proteins', 'Retrospective Studies', 'Stroke', 'Thrombolytic Therapy', 'Tissue Plasminogen Activator', 'Treatment Outcome'] | 31,478,125 | [['M01.060.116.100'], ['C10.228.140.300.150', 'C14.907.253.092'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of analgesia and cardiorespiratory effects of epidurally administered butorphanol in isoflurane-anesthetized dogs. | OBJECTIVE: To determine variations in minimal alveolar concentration (MAC) of isoflurane and analgesic and cardiorespiratory effects of lumbosacral epidural administration of 0.25 mg of butorphanol/kg of body weight in dogs.ANIMALS: 16 healthy male dogs.PROCEDURE: Dogs were anesthetized with isoflurane alone. Eight dog... | ['Analgesia, Epidural', 'Analgesics, Opioid', 'Anesthetics, Inhalation', 'Animals', 'Blood Pressure', 'Butorphanol', 'Carbon Dioxide', 'Dogs', 'Electric Stimulation', 'Heart Rate', 'Hemodynamics', 'Isoflurane', 'Male', 'Oxygen', 'Pulmonary Alveoli', 'Respiration', 'Tissue Distribution'] | 8,896,688 | [['E03.091.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.132.577.249.165', 'D03.605.497.165', 'D03.633... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Successful treatment of plasma cell cheilitis with topical tacrolimus: report of two cases. | Plasma cell cheilitis is an uncommon chronic inflammatory dermatitis that presents with flat to slightly elevated erosive erythematous plaques. It is histologically characterized by plasma cell infiltrates into the mucosa. Other than the lip, genital areas are often involved, which is called plasma cell balanitis or vu... | ['Administration, Topical', 'Aged', 'Cheilitis', 'Humans', 'Immunosuppressive Agents', 'Male', 'Plasma Cells', 'Tacrolimus'] | 21,382,289 | [['E02.319.267.120'], ['M01.060.116.100'], ['C07.465.409.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['A11.063.438.725', 'A11.118.637.555.567.562.725', 'A15.145.229.637.555.567.562.725', 'A15.382.032.438.725', 'A15.382.490.555.567.562.725'], ['D02.540.505.810']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antimicrobial, Cytotoxic, Anti-Inflammatory, and Antioxidant Activity of Culinary Processed Shiitake Medicinal Mushroom (Lentinus edodes, Agaricomycetes) and Its Major Sulfur Sensory-Active Compound-Lenthionine. | The antimicrobial, cytotoxic, anti-inflammatory, and antioxidant properties of aqueous extracts of raw and culinary processed shiitake mushrooms were evaluated and compared with those of lenthionine (1,2,3,5,6-penta-thiepane), the principal aroma-bearing substance of the shiitake medicinal mushroom (Lentinus edodes). A... | ['Anti-Bacterial Agents', 'Anti-Inflammatory Agents', 'Antifungal Agents', 'Antioxidants', 'Bacteria', 'Cell Line, Tumor', 'Cytokines', 'Cytotoxins', 'Fungi', 'HeLa Cells', 'Hep G2 Cells', 'Humans', 'Microbial Sensitivity Tests', 'Shiitake Mushrooms', 'Thiepins', 'Yeasts'] | 29,773,008 | [['D27.505.954.122.085'], ['D27.505.954.158'], ['D27.505.954.122.136'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B03'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D27.888.569.213'], ['B01.300'], ['A11.251.210.190.400', 'A11.251.860.180.400', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thermal analysis of the spores of Bacillus cereus with special reference to heat activation. | The heat activation of bacterial spores was studied by means of differential thermal analysis in the temperature range 30-110 degrees C using the spores of Bacillus cereus. The thermogram showed three endothermic peaks at 56, 95, and 103 degrees C with one exothermic peak at 105 degrees C during the heating process. Th... | ['Bacillus cereus', 'Bacterial Proteins', 'Calorimetry, Differential Scanning', 'Cell Wall', 'Hot Temperature', 'Protein Conformation', 'Spores, Bacterial'] | 105,794 | [['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218.252'], ['D12.776.097'], ['E05.196.131.310', 'E05.196.370.310'], ['A11.284.183'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Body temperature influences on ethanol elimination rate. | The effects of varying doses of ethanol injected IP on body temperature and the linear elimination rate were determined in long-sleep (LS) and short-sleep (SS) and C57BL6 mice. As the ethanol dose was increased, decreases in body temperature and rate of ethanol elimination were detected in all three mouse stocks. The c... | ['Animals', 'Body Temperature', 'Dose-Response Relationship, Drug', 'Ethanol', 'Female', 'Isoflurophate', 'Male', 'Metabolic Clearance Rate', 'Mice', 'Mice, Inbred C57BL', 'Phenobarbital', 'Phenotype'] | 3,593,533 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.375'], ['D02.705.429.750.249'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Muscle carnitine deficiency. Genetic heterogeneity. | Two types of lipid storage myopathy have been associated with decreased content of carnitine in muscle. In "muscle carnitine deficiency", carnitine concentration is normal in serum, but reduced in muscle. In "systemic carnitine deficiency", apparently due to imparied synthesis of carnitine in the liver, carnitine conte... | ['Adult', 'Carnitine', 'Carnitine O-Palmitoyltransferase', 'Female', 'Humans', 'Lipid Metabolism', 'Muscles', 'Muscular Diseases', 'NADH Tetrazolium Reductase', 'Oxidation-Reduction', 'Palmitates'] | 438,852 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Platelet aggregation and reversible platelet aggregates in type I-diabetes staged by retinal fluorescein angiography. | In 70 patients with juvenile-onset, insulin-dependent (type I) diabetes and 75 age- and sex-matched controls the reversible platelet aggregates expressed as platelet count ratio (PCR) and the ADP-induced platelet aggregation were studied. Retinal microangiopathy was staged by retinal fluorescein angiography. The mean P... | ['Adenosine Diphosphate', 'Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Collagen', 'Diabetes Mellitus, Type 1', 'Diabetic Retinopathy', 'Female', 'Fluorescein Angiography', 'Humans', 'Male', 'Platelet Aggregation', 'Platelet Count'] | 7,284,054 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E01.370.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Consensus Report on Shigella Controlled Human Infection Model: Conduct of Studies. | Shigella causes morbidity and mortality worldwide, primarily affecting young children living in low-resource settings. It is also of great concern due to increasing antibiotic resistance, and is a priority organism for the World Health Organization. A Shigella vaccine would decrease the morbidity and mortality associat... | ['Clinical Trials as Topic', 'Consensus', 'Consensus Development Conferences as Topic', 'Drug Development', 'Dysentery, Bacillary', 'Humans', 'Models, Biological', 'Research Report', 'Shigella', 'Shigella Vaccines', 'United States'] | 31,816,068 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F01.829.316.068', 'F02.463.785.373.433'], ['L01.178.682.759.150', 'N03.540.199.205'], ['E05.290', 'H01.158.703.007.338', 'H01.181.466.338'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['B01.050.150.900.649.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
A comparative estimation of the combined cortical thickness of various bone sites. | Measurement of the cortical thickness of long bones is the best method of quantitatively diagnosing osteoporosis. Combined cortical thickness (CCT) is as good as, or better than more complicated indices. In osteoporosis studies, the problem lies in finding a physiologically consistent bone site . The CCT of the lower s... | ['Adult', 'Bone and Bones', 'Female', 'Humans', 'Humerus', 'Metacarpus', 'Osteoporosis', 'Radiography', 'Radius'] | 7,209,568 | [['M01.060.116'], ['A02.835.232', 'A10.165.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.090.400'], ['A01.378.800.667.572'], ['C05.116.198.579', 'C18.452.104.579'], ['E01.370.350.700'], ['A02.835.232.087.090.700']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Time and dose dependencies of effects of nerve growth factor on sympathetic and sensory neurons in neonatal rats. | Nerve growth factor (NGF) plays a role in the development of several components of the sympathetic and sensory nervous systems. The objectives of this study were to examine the time and dose dependencies of some of the well known effects of NGF on sympathetic ganglia and to examine qualitatively and quantitatively the ... | ['Adrenal Glands', 'Animals', 'Animals, Newborn', 'Blood Pressure', 'Ganglia, Spinal', 'Ganglia, Sympathetic', 'Heart Rate', 'Kinetics', 'Nerve Growth Factors', 'Neurons', 'Rats', 'Rats, Inbred Strains'] | 7,059,824 | [['A06.300.071'], ['B01.050'], ['B01.050.050.282'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['A08.340.315.350', 'A08.800.050.300.300', 'A08.800.050.800.300'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G01.374.661', 'G02.111.490'], ['D12.644.276.... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Computed tomography of blunt abdominal trauma. | Experience with over 500 cases at this institution and reports from other institutions have established CT as an accurate and clinically useful tool in the evaluation of patients with blunt abdominal trauma. Careful attention to technique is essential since artifacts may simulate or obscure traumatic lesions. CT is hig... | ['Abdominal Injuries', 'Fatty Liver', 'Hemoperitoneum', 'Humans', 'Kidney', 'Liver', 'Pancreas', 'Peritoneal Cavity', 'Spleen', 'Therapeutic Irrigation', 'Tomography, X-Ray Computed', 'Wounds, Nonpenetrating'] | 6,635,171 | [['C26.017'], ['C06.552.241'], ['C06.844.400', 'C23.550.414.888'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['A03.620'], ['A03.734'], ['A01.923.047.025.600.678'], ['A10.549.700', 'A15.382.520.604.700'], ['E02.779.492.500', 'E02.831.535.492.500', 'E05.927'], ['E01.370.350.350.810', 'E01.370.350.... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomic Locking Plate for Displaced Intraarticular Calcaneal Fracture: Design and Application. | Calcaneal fracture can lead to long-term disability and have a considerable economic effect. Most calcaneal fractures are intraarticular fractures involving the posterior facet of the subtalar joint. Treating displaced intraarticular calcaneal fractures is complicated because of the lack of an optimal treatment option.... | ['Adult', 'Bone Plates', 'Calcaneus', 'Equipment Design', 'Female', 'Foot Injuries', 'Fracture Fixation, Internal', 'Humans', 'Intra-Articular Fractures', 'Male', 'Middle Aged', 'Radiography', 'Young Adult'] | 28,888,405 | [['M01.060.116'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['A02.835.232.043.300.710.300'], ['E05.320'], ['C26.558.300'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.404.505'], ['M01.060.116.630'], ['E01.370.350.700'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of a dopamine agonist on the pharmacodynamics of levodopa in Parkinson disease. | BACKGROUND: Treatment of Parkinson disease commonly includes levodopa and dopamine agonists; however, the interaction of these 2 drugs is poorly understood.OBJECTIVE: To examine the effects of a dopamine agonist on the motor response to levodopa.DESIGN: Double-blind, randomized, placebo-controlled, crossover clinical t... | ['Adult', 'Aged', 'Aged, 80 and over', 'Benzothiazoles', 'Brain', 'Cross-Over Studies', 'Dopamine Agonists', 'Double-Blind Method', 'Drug Synergism', 'Drug Therapy, Combination', 'Dyskinesia, Drug-Induced', 'Female', 'Humans', 'Infusions, Intravenous', 'Levodopa', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care... | 20,065,126 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D03.383.129.708.089', 'D03.633.100.185'], ['A08.186.211'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Type-D personality and ankle brachial index as predictors of impaired quality of life and depressive symptoms in peripheral arterial disease. | BACKGROUND: Patient-based outcomes, such as impaired quality of life (QOL) and depression, may adversely affect the clinical course of patients with peripheral arterial disease (PAD). Disease severity indices, including the ankle brachial index, are only partially associated with these outcomes.OBJECTIVE: To examine wh... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Pressure', 'Depression', 'Exercise Test', 'Female', 'Follow-Up Studies', 'Forecasting', 'Health Status', 'Humans', 'Intermittent Claudication', 'Male', 'Medical History Taking', 'Middle Aged', 'Peripheral Vascular Diseases', 'Personality', 'Physical Examination', 'Prospecti... | 17,638,805 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['F01.145.126.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.320'], ['I01.240.425', 'N01.224... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparison of stated and measured patient heights and weights. | Stated and measured patient heights and weights were compared, and the clinical importance of any differences was determined. A total of 112 health-clinic patients were interviewed for height and weight determinations. They were divided into four groups: men 21-35 years old; men 65 years and older; women 21-35 years ol... | ['Adult', 'Aged', 'Aging', 'Biometry', 'Body Height', 'Body Surface Area', 'Body Weight', 'Energy Metabolism', 'Female', 'Humans', 'Male', 'Sex Factors'] | 7,081,255 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['E05.318.740.225', 'N06.850.505.200'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.231', 'E05.041.124.231', 'G07.100.100.231'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Low loss and high speed silicon optical modulator based on a lateral carrier depletion structure. | A high speed and low loss silicon optical modulator based on carrier depletion has been made using an original structure consisting of a p-doped slit embedded in the intrinsic region of a lateral pin diode. This design allows a good overlap between the optical mode and carrier density variations. Insertion loss of 5 dB... | ['Equipment Design', 'Equipment Failure Analysis', 'Optics and Photonics', 'Semiconductors', 'Signal Processing, Computer-Assisted', 'Silicon'] | 18,521,165 | [['E05.320'], ['E05.325.192'], ['H01.671.617', 'J01.293.688'], ['E07.305.625'], ['L01.224.800'], ['D01.268.513.937']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Monosodium urate crystals induce oxidative stress in human synoviocytes. | BACKGROUND: Gout is the most common inflammatory arthropathy of metabolic origin and it is characterized by intense inflammation, the underlying mechanisms of which are unknown. The aim of this study was to evaluate the oxidative stress in human fibroblast-like synoviocytes (FLS) exposed to monosodium urate (MSU) cryst... | ['Apoptosis', 'Blotting, Western', 'Cell Survival', 'Cells, Cultured', 'Fibroblasts', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Gout', 'Humans', 'Microscopy, Electron, Transmission', 'Oxidative Stress', 'Reactive Nitrogen Species', 'Reactive Oxygen Species', 'Real-Time Polymerase Chain Reaction', 'Synoviocyt... | 27,209,322 | [['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.346'], ['A11.251'], ['A11.329.228'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E0... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peripheral osteopenia in adult patients with insulin-dependent diabetes mellitus. | Alterations in bone metabolism in diabetes mellitus is a topic of special interest. Bone blood flow is increased in the distal limb of diabetic patients, which is believed to increase osteoclastic activity. We measure bone mineral density using dual-photon absorptiometry in the distal lower limb, the femoral neck, and ... | ['Absorptiometry, Photon', 'Adult', 'Aged', 'Albuminuria', 'Body Mass Index', 'Bone Density', 'Bone Diseases, Metabolic', 'Case-Control Studies', 'Chi-Square Distribution', 'Creatinine', 'Diabetes Mellitus, Type 1', 'Female', 'Femur', 'Glycated Hemoglobin A', 'Humans', 'Leg', 'Lumbar Vertebrae', 'Male', 'Middle Aged', ... | 8,846,677 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116'], ['M01.060.116.100'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'], ['C05.116.198', 'C18.452.104'], ['E05.318.372.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Specific duodenal and faecal bacterial groups associated with paediatric coeliac disease. | AIMS: To identify specific gut bacteria associated with coeliac disease (CD) at diagnosis and after treatment with a gluten-free diet (GFD) in a paediatric population.METHODS: 30 and 18 faecal samples from untreated and treated CD patients and 25 and 8 biopsy samples from untreated and treated CD patients, respectively... | ['Bacteria', 'Bacterial Typing Techniques', 'Biopsy', 'Case-Control Studies', 'Celiac Disease', 'Child', 'Child, Preschool', 'Diet, Gluten-Free', 'Duodenum', 'Feces', 'Female', 'Humans', 'Male', 'Polymerase Chain Reaction'] | 18,996,905 | [['B03'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.469.637.250', 'C18.452.603... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mouse minor satellite DNA genetically maps to the centromere and is physically linked to the proximal telomere. | As an adjunct to attempts to define functionally important sequences at human centromeres, we have undertaken a long-range physical analysis of these regions in the mouse. Mouse centromeres are usually situated very close to the chromosome ends and are closely associated with minor satellite sequences on the basis of c... | ['Alleles', 'Animals', 'Blotting, Southern', 'Centromere', 'Chromosome Mapping', 'DNA, Satellite', 'Electrophoresis, Agar Gel', 'Electrophoresis, Gel, Pulsed-Field', 'Genetic Linkage', 'Genetic Markers', 'Mice', 'Muridae', 'Polymorphism, Restriction Fragment Length', 'Reading Frames', 'Telomere', 'Translocation, Geneti... | 1,685,135 | [['G05.360.340.024.340.030'], ['B01.050'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['E05.393.183'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['E05.196.40... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Integrating PET and CT information to improve diagnostic accuracy for lung nodules: A semiautomatic computer-aided method. | UNLABELLED: Our objective was to develop and evaluate 3 semiautomatic computer-aided diagnostic (CAD) schemes for distinguishing between benign and malignant pulmonary nodules by use of features extracted from CT, 18F-FDG PET, and both CT and 18F-FDG PET.METHODS: We retrospectively collected 92 consecutive cases of pul... | ['Aged', 'Automation', 'Diagnosis, Computer-Assisted', 'False Positive Reactions', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Lung', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Positron-Emission Tomography', 'ROC Curve', 'Radiographic Image Interpretation, Computer-Assisted', 'Software', 'Solitary Pulmonary Nodule', ... | 16,818,939 | [['M01.060.116.100'], ['J01.897.104'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.354.506'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.3... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Percutaneous progesterone use and risk of breast cancer: results from a French cohort study of premenopausal women with benign breast disease. | Percutaneous progesterone topically applied on the breast has been proposed and widely used in the relief of mastalgia and benign breast disease by numerous gynecologists and general practitioners. However, its chronic use has never been evaluated in relation to breast cancer risk. The association between percutaneous ... | ['Administration, Cutaneous', 'Adult', 'Breast Diseases', 'Breast Neoplasms', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'France', 'Humans', 'Middle Aged', 'Pain', 'Premenopause', 'Progesterone', 'Proportional Hazards Models', 'Risk Factors', 'Surveys and Questionnaires'] | 10,403,900 | [['E02.319.267.120.060'], ['M01.060.116'], ['C17.800.090'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The impact of ocular trauma during the Nepal earthquake in 2015. | BACKGROUND: Nepal was struck by a massive earthquake on the 25th April 2015 and major aftershock on the 12th of May 2015, resulting in widespread devastation with a death toll in the thousands. The burden of ocular trauma resulting from the recent earthquakes in Nepal has not been described thus far. The aim of this st... | ['Adolescent', 'Adult', 'Aged', 'Blindness', 'Child', 'Child, Preschool', 'Earthquakes', 'Eye Injuries', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nepal', 'Prognosis', 'Retrospective Studies', 'Trauma Severity Indices', 'Visual Acuity', 'Young Adult'] | 28,351,353 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['M01.060.406'], ['M01.060.406.448'], ['G01.311.250', 'N06.230.100.230.200'], ['C10.900.300.284.250', 'C11.297', 'C26.915.300.425.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.1... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Calculation of False Discovery Rate for Peptide and Protein Identification. | Shotgun proteomics is the method of choice for large-scale protein identification. However, the use of a robust statistical workflow to validate such identification is mandatory to minimize false matches, ambiguities, and amplification of error rates from spectra to proteins. In this chapter we emphasize the key concep... | ['Computational Biology', 'Databases, Protein', 'Peptides', 'Proteins', 'Proteomics', 'Search Engine', 'Software', 'Tandem Mass Spectrometry'] | 31,552,628 | [['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['D12.644'], ['D12.776'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['L01.470.875'], ['L01.224.90... | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Multiple complications of acute unilateral rhinosinusitis--a case report]. | INTRODUCTION: Intracranial or orbital complications after chronic and acute rhinosinusitis are rare, but could be dangerous. The complications of acute rhinosinusitis more often are observed in young patients. The combination of both intracranial and orbital complications together is found after acute inflammation.MATE... | ['Acute Disease', 'Adult', 'Brain Abscess', 'Epidural Abscess', 'Humans', 'Male', 'Radiography', 'Rhinitis', 'Sinusitis', 'Streptococcal Infections', 'Treatment Outcome'] | 21,916,225 | [['C23.550.291.125'], ['M01.060.116'], ['C01.207.090', 'C01.830.025.160', 'C10.228.140.116', 'C10.228.228.090'], ['C01.207.300', 'C01.207.709.350', 'C01.830.025.325', 'C10.228.228.300', 'C10.228.228.709.350', 'C10.228.854.303'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['C01.748.674', 'C08.... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Calcineurin, a calcium/calmodulin-dependent protein phosphatase, is involved in movement, fertility, egg laying, and growth in Caenorhabditis elegans. | Calcineurin is a Ca(2+)-calmodulin-dependent serine/threonine protein phosphatase that has been implicated in various signaling pathways. Here we report the identification and characterization of calcineurin genes in Caenorhabditis elegans (cna-1 and cnb-1), which share high homology with Drosophila and mammalian calci... | ['Amino Acid Sequence', 'Animals', 'Blotting, Northern', 'Caenorhabditis elegans', 'Calcineurin', 'Cell Division', 'Cell Movement', 'Cloning, Molecular', 'DNA, Complementary', 'Dose-Response Relationship, Drug', 'Gene Deletion', 'Gene Library', 'Green Fluorescent Proteins', 'Immunohistochemistry', 'Luminescent Proteins... | 12,221,132 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.500.500.294.400.875.660.250.250'], ['D08.811.277.352.650.625.150', 'D12.644.360.087', 'D12.776.476.087'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Oral microbiota dysbiosis and its association with Henoch-Sch?nlein Purpura in children. | BACKGROUND: The pathogenesis of microbes in allergic diseases has been demonstrated and our previous research indicates that microbiota causing gut disorders in children is associated with Henoch-Sch?nlein Purpura. However, the role of oral microbiota in Henoch-Sch?nlein Purpura remains unknown.METHOD: A total of 164 c... | ['Adolescent', 'Bacteroidetes', 'Child', 'Child, Preschool', 'Dysbiosis', 'Female', 'Firmicutes', 'Humans', 'Male', 'Microbiota', 'Mouth', 'Proteobacteria', 'Purpura, Schoenlein-Henoch', 'RNA, Ribosomal, 16S'] | 30,342,346 | [['M01.060.057'], ['B03.440.080'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.308'], ['B03.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['B03.660'], ['C14.907.940.777', 'C15.378.100.802.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of diflubenzuron on a complex laboratory stream community. | Effects were assessed on the total biological community in complex laboratory streams caused by continuous exposure to diflubenzuron (1-(4-chlorophenyl)-3-(2,6-difluorobenzoyl) urea). The insect fauna suffered direct toxic effects at concentrations of 1.0 microgram/L and greater. The algal and fungal floras were mildly... | ['Animals', 'Bacteria', 'Diflubenzuron', 'Eukaryota', 'Fungi', 'Insect Control', 'Insecta', 'Juvenile Hormones', 'Marine Biology', 'Water Microbiology'] | 6,803,677 | [['B01.050'], ['B03'], ['D02.065.950.681.280', 'D02.455.426.559.389.703.280', 'D06.472.445.573.666.170'], ['B01'], ['B01.300'], ['N06.850.780.200.650.425'], ['B01.050.500.131.617'], ['D06.472.445.573.666'], ['H01.158.273.248.750.500', 'H01.277.249.750.500', 'H01.277.750.500'], ['H01.158.273.540.274.777', 'N06.850.425.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Real-time glutamate measurements in the putamen of awake rhesus monkeys using an enzyme-based human microelectrode array prototype. | Commonly used for research studies in the central nervous system, microdialysis has revealed a link between dysregulation of the excitatory neurotransmitter glutamate and ischemia and seizure, however limitations like slow temporal resolution have stalled the advancement of microdialysis as a diagnostic tool. We have d... | ['Animals', 'Electrochemistry', 'Enzymes', 'Female', 'Glutamic Acid', 'Humans', 'Macaca mulatta', 'Magnetic Resonance Imaging', 'Microdialysis', 'Microelectrodes', 'Putamen', 'Wakefulness'] | 19,850,078 | [['B01.050'], ['H01.181.529.307'], ['D08.811'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['E01.370.350.825.500'], ['E05.196.353.500'], ['E07.305.250.500'], ['A08.186.211.200.885.287.249.48... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The Accuracy of Conformation of a Generic Surface Mesh for the Analysis of Facial Soft Tissue Changes. | PURPOSE: Three dimensional analysis of the face is required for the assessment of complex changes following surgery, pathological conditions and to monitor facial growth. The most suitable method may be "dense surface correspondence".MATERIALS AND METHODS: This method utilizes a generic facial mesh and "conformation pr... | ['Anatomic Landmarks', 'Cone-Beam Computed Tomography', 'Connective Tissue', 'Face', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Male', 'Mandible', 'Maxilla', 'Photogrammetry'] | 27,093,637 | [['A01.111'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['A10.165'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['E01.370.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Identification of novel hits as highly prospective dual agonists for mu and kappa opioid receptors: an integrated in silico approach. | Opioid agonists are used clinically for the treatment of acute and chronic pain, however, their clinical use is limited due to the presence of undesired side effects. Dual agonists, simultaneously targeting mu and kappa opioid receptors, show fewer side effects than that of selective agonists. In the present work, 2D- ... | ['Blood-Brain Barrier', 'Humans', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Morphinans', 'Multiprotein Complexes', 'Protein Binding', 'Quantitative Structure-Activity Relationship', 'Receptors, Opioid, kappa', 'Receptors, Opioid, mu'] | 28,071,341 | [['A07.035', 'A08.186.211.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595.249', 'L01.224.160.249'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D03.132.577.249', 'D03.605.497', 'D03.633.400.686', 'D04.615.723.795'], ['D05.500'], ['G02.111.679', 'G03.808'], ['G02.111.830.500', 'G07... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development of a method for the analysis of nucleotides from the mantle tissue of the mussel Mytilus galloprovincialis. | Reversed-phase HPLC was applied to obtain a sensitive and efficient means for quantitating nucleotides in the mussel Mytilus galloprovincialis. We obtained a good separation of adenylic, guanylic, uridylic and cytidylic nucleotides. Adenine nucleotides play a critical role in the regulation and integration of cellular ... | ['Animals', 'Bivalvia', 'Calibration', 'Chromatography, High Pressure Liquid', 'Nucleotides', 'Spectrophotometry, Ultraviolet'] | 10,999,629 | [['B01.050'], ['B01.050.500.644.080'], ['E05.978.155'], ['E05.196.181.400.300'], ['D09.408.620', 'D13.695'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Prescriptions for individually prepared dermatologic agents. I]. | The present paper reports the results of a survey of contemporary medical prescriptions of solutions, suspensions and emulsions used in dermatological practice. The obtained results were compared with the district prescription lists from Slovakia. The analysis of contemporary prescription was carried out in 27 district... | ['Czechoslovakia', 'Dermatologic Agents', 'Drug Compounding', 'Drug Prescriptions'] | 1,451,194 | [['Z01.586.250'], ['D27.505.954.444'], ['E05.916.270'], ['E02.319.307', 'N02.421.668.778.500']] | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Ultrastructure of the posterior corneal stroma. | PURPOSE: To reinvestigate the ultrastructure of the posterior stroma of the human cornea and to correlate the findings with the stromal behavior after big-bubble creation.DESIGN: Observational consecutive 3-center case series.SPECIMENS: Fresh corneoscleral buttons from human donors (n = 19) and organ-cultured corneoscl... | ['Aged', 'Collagen Type III', 'Collagen Type IV', 'Collagen Type VI', 'Corneal Diseases', 'Corneal Keratocytes', 'Corneal Stroma', 'Descemet Membrane', 'Descemet Stripping Endothelial Keratoplasty', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Microscopy, Electron, Transmission', 'Middle Aged', 'Organ Culture... | 25,458,195 | [['M01.060.116.100'], ['D05.750.078.280.300.300', 'D12.776.860.300.250.300.300'], ['D12.776.860.300.250.400.100'], ['D12.776.860.300.250.400.200'], ['C11.204'], ['A11.329.228.109'], ['A09.371.060.217.228'], ['A09.371.060.217.271', 'A10.615.179.437'], ['E02.095.147.725.262', 'E04.540.825.374.112', 'E04.936.580.262'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Novel MAF mutation in a family with congenital cataract-microcornea syndrome. | PURPOSE: To further unravel the molecular genetic background for the association congenital cataract-microcornea (CCMC).METHODS: DNA variation was pointed out by direct DNA sequencing of 13 lens-expressed cataract genes from three CCMC families and one isolated case. The mutation screening included seven crystalline ge... | ['Amino Acid Substitution', 'Arginine', 'Cataract', 'Cornea', 'DNA', 'Eye Abnormalities', 'Female', 'Humans', 'Infant, Newborn', 'Leucine Zippers', 'Male', 'Mutation', 'Pedigree', 'Phenotype', 'Proto-Oncogene Proteins c-maf', 'Serine'] | 17,982,426 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['C11.510.245'], ['A09.371.060.217'], ['D13.444.308'], ['C11.250', 'C16.131.384'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G02.111.570.820.709.275.500.520'], ['G05.365.590'], ['E05.393.673... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stereoradiography imaging motion artifact: does it affect radiographic measures after spinal instrumentation? | PURPOSE: Stereoradiography imaging (SRI) is an accurate and reliable low-dose radiographic method. However, patients must remain motionless during image acquisition. Motion artifacts are frequently noted. The aims of the study were to determine the incidence of the SRI motion artifact and assess if motion during SRI ac... | ['Adolescent', 'Adult', 'Artifacts', 'Humans', 'Movement', 'Neurosurgical Procedures', 'Radiostereometric Analysis', 'Spine', 'Young Adult'] | 26,940,057 | [['M01.060.057'], ['M01.060.116'], ['E05.047'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['E04.525'], ['E01.370.350.600.630.750', 'E01.370.350.700.750'], ['A02.835.232.834'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Serological survey for bovine leptospirosis in the Volksrust district. | Serum samples (n = 860) from cattle in the Volksrust district were tested for Leptospira antibody titres. Seventeen (2%) of the animals were positive for leptospirosis, while 9(1%) animals showed suspect reactions. Titres against L. hardjo, L. pomona, and L. tarassovi were the most prevalent. | ['Agglutination Tests', 'Animals', 'Antibodies, Bacterial', 'Cattle', 'Cattle Diseases', 'Leptospira', 'Leptospirosis', 'Prevalence', 'South Africa'] | 9,022,848 | [['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['B03.440.400.425.475.475', 'B03.851.475.475'], ['C01.150.252.400.794.511'], ['E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effect of silibinin in reducing inflammatory pathways in in vitro and in vivo models of infection-induced preterm birth. | Infection-induced preterm birth is the largest cause of infant death and of neurological disabilities in survivors. Silibinin, from milk thistle, exerts potent anti-inflammatory activities in non-gestational tissues. The aims of this study were to determine the effect of silibinin on pro-inflammatory mediators in (i) h... | ['Animals', 'Cyclooxygenase 2', 'Extraembryonic Membranes', 'Female', 'Humans', 'Inflammation', 'Interleukin-1beta', 'Interleukin-6', 'Interleukin-8', 'Lipopolysaccharides', 'Mice', 'Myometrium', 'Pregnancy', 'Premature Birth', 'Silybin', 'Silymarin'] | 24,647,589 | [['B01.050'], ['D08.811.600.720.750'], ['A10.615.284', 'A16.254.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.374.500.400.600', 'D23.529.374.465.131.600', 'D23.529.374.500.400.600'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of a primary target of thalidomide teratogenicity. | Half a century ago, thalidomide was widely prescribed to pregnant women as a sedative but was found to be teratogenic, causing multiple birth defects. Today, thalidomide is still used in the treatment of leprosy and multiple myeloma, although how it causes limb malformation and other developmental defects is unknown. H... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Carrier Proteins', 'Chick Embryo', 'Cullin Proteins', 'DNA-Binding Proteins', 'Embryo, Nonmammalian', 'Embryonic Development', 'Fibroblast Growth Factors', 'Forelimb', 'Gene Expression Regulation, Developmental', 'HeLa Cells', 'Humans', 'Mutant Proteins', 'Peptide Hy... | 20,223,979 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D12.776.157'], ['A13.350.150', 'A16.331.200'], ['D08.811.464.938.750.750.500', 'D12.776.167.175'], ['D12.776.260'], ['A13.350', 'A16.331'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Space radiation measurements on-board ISS--the DOSMAP experiment. | The experiment 'Dosimetric Mapping' conducted as part of the science program of NASA's Human Research Facility (HRF) between March and August 2001 was designed to measure integrated total absorbed doses (ionising radiation and neutrons), heavy ion fluxes and its energy, mass and linear energy transfer (LET) spectra, ti... | ['Aerospace Medicine', 'Astronauts', 'Cosmic Radiation', 'Equipment Design', 'Equipment Failure Analysis', 'Occupational Exposure', 'Radiation Monitoring', 'Radiation Protection', 'Reproducibility of Results', 'Research', 'Research Design', 'Sensitivity and Specificity', 'Spacecraft'] | 16,604,663 | [['H02.403.029'], ['M01.526.173'], ['G01.060.185', 'G01.750.750.235', 'G16.500.200', 'N06.230.300.100.300'], ['E05.320'], ['E05.325.192'], ['N06.850.460.350.600'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['N06.850.810.425'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.7... | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
Importance of volume factors in dialysis related hypertension. | OBJECTIVE: To evaluate the relation between total body water and dialysis related hypertension.PATIENTS AND METHODS: Thirty stable chronic hemodialysis patients were studied. Twenty-four-hour ambulatory blood pressure on the day before dialysis, blood pressure before and after dialysis, weight gain, ultrafiltration and... | ['Aged', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Body Water', 'Extracellular Space', 'Female', 'Humans', 'Hypertension, Renal', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Water-Electrolyte Imbalance'] | 9,247,775 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['A12.207.200'], ['A10.082.500', 'A11.284.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.331', 'C13.351.968.419.331', 'C14.907.489.631'], ['C12.777.419.780.750.500', 'C13.351.968.419.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chemical and spectroscopic analysis of a phenobarbital-ephedrine complex. | A complex of phenobarbital and ephedrine was prepared and characterized. The complex was differentiated from physical mixtures of the two drugs by TLC and IR spectroscopy. NMR spectroscopy was used to verify the proportion of each drug in the complex and to confirm the existence of intermolecular binding. Mass spectrom... | ['Chemical Phenomena', 'Chemistry', 'Chromatography, Thin Layer', 'Ephedrine', 'Magnetic Resonance Spectroscopy', 'Phenobarbital', 'Spectrophotometry, Infrared'] | 886,437 | [['G02'], ['H01.181'], ['E05.196.181.400.537'], ['D02.033.100.624.302', 'D02.033.755.624.302', 'D02.092.063.624.302', 'D02.092.471.683.430'], ['E05.196.867.519'], ['D03.383.742.698.253.650'], ['E05.196.712.726.676', 'E05.196.867.826.676']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Polyvinyl alcohol/gelatin nanocomposite containing ZnO, TiO2 | Recently, oxo-biodegradable polymers have attracted much attention due to taking less time to break down after disposal in comparison to ordinary polymers. Polyvinyl alcohol/gelatin (PVA/G) nanocomposite films, containing ZnO, TiO2 or ZnO/TiO2 nanoparticles supported on 4A zeolite (4A z), are novel active packaging tha... | ['Animals', 'Anti-Bacterial Agents', 'Bacterial Load', 'Escherichia coli', 'Food Packaging', 'Food Storage', 'Gelatin', 'Listeria monocytogenes', 'Nanocomposites', 'Nanoparticles', 'Penaeidae', 'Polyvinyl Alcohol', 'Refrigeration', 'Staphylococcus aureus', 'Titanium', 'Zeolites', 'Zinc Oxide'] | 31,669,767 | [['B01.050'], ['D27.505.954.122.085'], ['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['J01.576.423.200.375', 'J01.576.423.850.600', 'J01.576.761.400'], ['J01.576.423.200.387'], ['D12.776.860.47... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A novel dystrophin isoform is required for normal retinal electrophysiology. | Dystrophin is present in the outer plexiform layer of the retina and is required for normal retinal function as measured by electroretinography. We describe the identification of a novel isoform of dystrophin (Dp260) present in the mouse retina. The unique 5' terminus of the mRNA originates from a newly identified exon... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Base Sequence', 'Cloning, Molecular', 'DNA, Complementary', 'Dystrophin', 'Electrophysiology', 'Exons', 'Humans', 'Male', 'Mice', 'Mice, Mutant Strains', 'Molecular Sequence Data', 'Muscular Dystrophy, Animal', 'Polymerase Chain Reaction', 'RNA, Messenger', ... | 7,633,443 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.776.21... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization. | We have reconstituted the holoenzyme of the human mitochondrial DNA polymerase from cloned and overexpressed catalytic and accessory subunits. We have examined the polymerization activity of the catalytic subunit alone and of the holoenzyme to establish the function of the accessory subunit in this two subunit enzyme. ... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Catalytic Domain', 'DNA Polymerase gamma', 'DNA, Complementary', 'DNA-Directed DNA Polymerase', 'Deoxyadenine Nucleotides', 'Drosophila melanogaster', 'Holoenzymes', 'Humans', 'Kinetics', 'Mitochondria', 'Molecular Sequence Data', 'Peptide Fragments', 'Phosphorus-Oxy... | 10,677,218 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D08.811.913.696.445.308.300.169', 'D12.776.575.280'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D08.811.913.696.445.308.300'], ['D03.633.100... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Perceptions of health and somatic sensations in women reporting premenstrual syndrome and premenstrual dysphoric disorder. | Focus on bodily sensations may be involved in the etiology of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). This study investigated the relationship between two types of somatic self-focus (i.e., health anxiety and anxiety sensitivity) and health-related quality of life (QOL) in women with pro... | ['Adolescent', 'Anxiety', 'Attitude to Health', 'Female', 'Humans', 'Illness Behavior', 'Mass Screening', 'Personality Inventory', 'Premenstrual Syndrome', 'Psychometrics', 'Quality of Life', 'Somatoform Disorders', 'Young Adult'] | 23,995,034 | [['M01.060.057'], ['F01.470.132'], ['F01.100.150', 'N05.300.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.499'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['F04.711.647.513'], ['C23.550.568.968'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Development and application of a dual-purpose nanoparticle platform for delivery and imaging of siRNA in tumors. | The vision of using a single therapeutic agent with sufficient generality to allow application to a wide variety of diseases, yet specific enough to permit intervention at single molecular stages of the pathology, is rapidly becoming a reality through the emergence of RNA interference. RNA interference can be used to i... | ['Animals', 'Carbocyanines', 'Drug Carriers', 'Female', 'Genetic Therapy', 'Magnetic Resonance Imaging', 'Mice', 'Nanoparticles', 'Neoplasms', 'Peptides', 'RNA Interference', 'RNA, Small Interfering', 'Spectroscopy, Near-Infrared'] | 19,495,684 | [['B01.050'], ['D02.455.326.397.300'], ['D26.255.260', 'E02.319.300.380'], ['E02.095.301', 'E05.393.420.301'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['J01.637.512.600'], ['C04'], ['D12.644'], ['G05.308.203.374.790'], ['D13.150.650.700', 'D13.444.735.150.700', 'D13.444.735.790.552.875'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The protective effects of hypoxia-induced hypometabolism in the Nautilus. | Specimens of Nautilus pompilius were trapped at depths of 225-300 m off the sunken barrier reef southeast of Port Moresby, Papua New Guinea. Animals transported to the Motupore Island laboratory were acclimated to normal habitat temperatures of 18 degrees C and then cannulated for arterial and venous blood sampling. Wh... | ['Acid-Base Equilibrium', 'Adaptation, Physiological', 'Animals', 'Arginine', 'Basal Metabolism', 'Carbon Dioxide', 'Heart Rate', 'Hydrogen-Ion Concentration', 'Hypoxia', 'Mollusca', 'Muscles', 'Myocardium', 'Oxygen', 'Respiration', 'Succinic Acid'] | 10,935,516 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['G07.025', 'G16.012.500'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G03.295.154'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G02.300'], ['C23.888.852.079'], ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The changing epidemiology of cerebral palsy. | AIM: To determine the prevalence of cerebral palsy in a specific population.METHODS: Multiple sources of ascertainment were used to create and maintain a register of all cases of cerebral palsy born to mothers resident in the counties of Merseyside and Cheshire in the years 1966 to 1989. Denominator data of infant birt... | ['Cerebral Palsy', 'England', 'Female', 'Humans', 'Infant Mortality', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Male', 'Prevalence'] | 8,976,681 | [['C10.228.140.140.254'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], ['M01.060.703.520.460'], ['M01.060.703.520'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.... | ['Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Survival variability and population density in fish populations. | To understand the processes that regulate the abundance and persistence of wild populations is a fundamental goal of ecology and a prerequisite for the management of living resources. Variable abundance data, however, make the demonstration of regulation processes challenging. A previously overlooked aspect in understa... | ['Age Distribution', 'Aging', 'Animals', 'Fishes', 'Geography', 'Larva', 'Models, Biological', 'Oceans and Seas', 'Population Density', 'Reproduction', 'Stochastic Processes', 'Survival Rate'] | 18,354,480 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['G07.345.124'], ['B01.050'], ['B01.050.150.900.493'], ['H01.277.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E05.599.395'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['N01.224.600', 'N06.850.505.400.600'], ['G08.686.784'], ['E05.318.740.996',... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
A comparison of methods for determining setting rate of amalgam. | Four methods were compared for determining the setting rate of amalgams. The resultant order of preference as a standard method was compressive strength at 30 minutes after preparation of the specimen, the time to the last transverse cut on a cylindrical specimen with a "guillotine" blade and the time to nonfracture of... | ['Absorption', 'Chemistry, Physical', 'Dental Amalgam', 'Hardness Tests', 'Mercury', 'Needles', 'Pressure', 'Stress, Mechanical', 'Time Factors'] | 1,057,906 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['H01.181.529'], ['D25.339.208.291', 'J01.637.051.339.208.291'], ['E05.417', 'E05.570.500.500', 'G01.374.647.457', 'G01.374.687.500'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['E07.612'], ['G01.374.715'], ['G01.374.835'], ['G01.910... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
HIV-Tat protein activates c-Jun N-terminal kinase and activator protein-1. | Human immunodeficiency virus-1 tat (HIV-tat) protein, like other proinflammatory cytokines (such as TNF), activates a wide variety of cellular responses, some of which play a critical role in progression of HIV infection. Whether HIV-tat, like TNF, also activates c-Jun N-terminal kinase (JNK) and the transcription fact... | ['Calcium-Calmodulin-Dependent Protein Kinases', 'Cell Line', 'Enzyme Activation', 'Free Radicals', 'Gene Products, tat', 'Genes, tat', 'HIV-1', 'Humans', 'JNK Mitogen-Activated Protein Kinases', 'Jurkat Cells', 'Kinetics', 'Mitogen-Activated Protein Kinase Kinases', 'Mitogen-Activated Protein Kinases', 'Protein Kinase... | 9,670,954 | [['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['A11.251.210'], ['G02.111.263', 'G03.328'], ['D01.339', 'D02.389'], ['D12.776.260.755.199', 'D12.776.930.900.199', 'D12.776.964.900.750.750', 'D12.776.964.925.984.400'], ['G05.360.340.024.340.364.875.850', 'G05.360.340.024.340.425.560', 'G05.3... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maternal occupational exposure to chemical substances and the risk of infants small-for-gestational-age. | BACKGROUND: The association between maternal occupational exposure to specific chemical substances (organic solvents, carbon tetrachloride, herbicides, chlorophenols, polychlorinated biphenyls, aromatic amines, lead and lead compounds, mercury and mercury compounds) and birth of small-for-gestational-age (SGA) infants ... | ['Adolescent', 'Adult', 'Amines', 'Chlorophenols', 'Confidence Intervals', 'Female', 'Germany, West', 'Hazardous Substances', 'Humans', 'Hydrocarbons, Aromatic', 'Infant, Newborn', 'Infant, Small for Gestational Age', 'Logistic Models', 'Maternal Exposure', 'Mercury', 'Occupational Exposure', 'Odds Ratio', 'Pregnancy',... | 10,361,609 | [['M01.060.057'], ['M01.060.116'], ['D02.092'], ['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['Z01.586.350'], ['D27.888.426'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559'], ['M01.060.703.520'], ['M01.060.703.52... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
New polarized light microscope with precision universal compensator. | A new type of polarized light microscope ('new pol-scope') for fast and orientation-independent measurement of birefringent fine structure has been developed. The design of the new pol-scope incorporates a precision universal compensator made from two liquid crystal variable retarders. A video camera and digital image ... | ['Microscopy, Polarization'] | 8,537,959 | [['E01.370.350.515.624', 'E05.595.624']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A survey of avian paramyxovirus type 1 infections among backyard poultry in New Zealand. | AIMS: To determine the presence and the pathotype of avian paramyxovirus type 1 (APMV-1), as well as the prevalence of APMV-1 antibodies, among backyard flocks of poultry in selected New Zealand locations.METHODS: Archival pooled (n = 162) tracheal and cloacal swabs collected from backyard poultry were tested for the p... | ['Animals', 'Base Sequence', 'Molecular Sequence Data', 'New Zealand', 'Newcastle Disease', 'Newcastle disease virus', 'Poultry', 'Serologic Tests'] | 23,611,028 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['L01.453.245.667'], ['Z01.639.760.747', 'Z01.678.100.747'], ['C01.925.782.580.600.080.600', 'C22.131.630'], ['B04.820.480.937.600.650.070.600'], ['B01.050.050.116.625', 'B01.050.150.900.248.690', 'G07.203.300.600.750', 'J02.500.600.750'], ['E01.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly. | Dihydrodipicolinate reductase (DHDPR) catalyses the second reaction in the diaminopimelate pathway of lysine biosynthesis in bacteria and plants. In contrast with the tetrameric bacterial DHDPR enzymes, we show that DHDPR from Vitis vinifera (grape) and Selaginella moellendorffii are dimeric in solution. In the present... | ['Amino Acid Motifs', 'Arabidopsis', 'Bacterial Proteins', 'Binding Sites', 'Coenzymes', 'Crystallography, X-Ray', 'Dihydrodipicolinate Reductase', 'Gene Expression', 'Kinetics', 'Lysine', 'Models, Molecular', 'NAD', 'NADP', 'Neisseria meningitidis', 'Picolinic Acids', 'Plant Proteins', 'Protein Binding', 'Protein Conf... | 29,187,521 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.097'], ['G02.111.570.120'], ['D08.211'], ['E05.196.309.742.225'], ['D08.811.682.660.275'], ['G05.297'], ['G01.374.661', 'G02.111.490'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['E05.599... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
What information can change the attitude of teachers toward the human papillomavirus vaccine? | AIM: We conducted a self-administered survey on the perception of teachers toward human papillomavirus (HPV) vaccine to determine the ways to increase their willingness to encourage its use.METHODS: Answers were obtained both prior to and after having the teachers read five brief information articles: (i) cervical canc... | ['Adult', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Papillomavirus Infections', 'Papillomavirus Vaccines', 'School Teachers', 'Uterine Cervical Neoplasms'] | 29,442,400 | [['M01.060.116'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['C01.925.256.650', 'C01.925.928.725'], ['D20.215.894.899.498'], ['M01.526.702.500'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.85... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Interstitial cells of the kidney medulla and the content of prostaglandins in the kidneys of rats after administration of indomethacin]. | A parallel study on the content of prostaglandins (PG) in the kidneys, the morphological condition of the medulla interstitial cells, and the activity of prostaglandin-dehydrogenase in rats given indometacyn for 5 days in a dose of 5 mg/kg was carried out. A considerable decrease in the content of PGA2 and PGE2 and an ... | ['Animals', 'Cyclooxygenase Inhibitors', 'Depression, Chemical', 'Hydroxyprostaglandin Dehydrogenases', 'Indomethacin', 'Kidney', 'Kidney Medulla', 'Male', 'Prostaglandins', 'Rats'] | 410,391 | [['B01.050'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.030.500'], ['G07.690.773.750'], ['D08.811.682.047.820.375'], ['D03.633.100.473.420'], ['A05.810.453'], ['A05.810.453.466'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histopathological study on experimental endophthalmitis induced by bloodstream infection with Candida albicans. | To investigate the details of the pathophysiology of endogenous fungal endophthalmitis (EFE), we performed sequential histological and ophthalmoscopic examination on a rabbit model comparing immunocompromised EFE developed using a steroid with an immunocompetent one intravenously inoculated with Candida albicans. The o... | ['Animals', 'Candida albicans', 'Candidiasis', 'Endophthalmitis', 'Fungemia', 'Histological Techniques', 'Immunocompromised Host', 'Leukocytes, Mononuclear', 'Male', 'Neutrophils', 'Ophthalmoscopy', 'Rabbits', 'Retina', 'Steroids'] | 17,314,423 | [['B01.050'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160'], ['C01.375.265', 'C11.294.265'], ['C01.150.703.492.594', 'C01.757.360', 'C23.550.470.790.500.360'], ['E01.370.225.750', 'E05.200.750'], ['G12.470'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'],... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence, risk factors and molecular characterization of Chlamydia trachomatis in pregnant women from C?rdoba, Argentina: A prospective study. | BACKGROUND: Chlamydia trachomatis causes the most prevalent bacterial Sexual Transmitted Infection. In pregnant women, untreated chlamydial infections are associated with abortions, premature rupture of membranes, postpartum endometritis, low birth weight and transmission to the newborn. In C?rdoba, Argentina, there is... | ['Abortion, Induced', 'Adolescent', 'Adult', 'Argentina', 'Chlamydia Infections', 'Chlamydia trachomatis', 'Female', 'Genotype', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Prevalence', 'Prospective Studies', 'Risk Factors', 'Sexual Behavior', 'Young Adu... | 31,150,440 | [['E04.520.050'], ['M01.060.057'], ['M01.060.116'], ['Z01.107.757.077'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.190.750'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The effect of dietary selenium deficiency on the antioxidant enzyme system in the gastrointestinal tract of the rat. | The effect of selenium deficiency on the glutathione content and antioxidant enzymes in the gastrointestinal mucosa was studied. It was found that under Se-deficiency the level of glutathione increased, whereas the activity of Se-dependent glutathione peroxidase decreased. The activities of catalase and glutathione-S-t... | ['Animals', 'Catalase', 'Diet', 'Digestive System', 'Glutathione', 'Glutathione Peroxidase', 'Glutathione Transferase', 'Intestinal Mucosa', 'Intestines', 'Lipid Peroxidation', 'Lipid Peroxides', 'Male', 'Malondialdehyde', 'Oxygen', 'Rats', 'Rats, Inbred Strains', 'Selenium', 'Superoxides'] | 1,324,517 | [['B01.050'], ['D08.811.682.732.332'], ['G07.203.650.240'], ['A03'], ['D12.644.456.448'], ['D08.811.682.732.500'], ['D08.811.913.225.500'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['G02.111.515', 'G03.295.531.587'], ['D01.248.497.158.685.750.637', 'D01.339.431.374.637', 'D01.650.550.750.600', 'D02.389.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An example of variation and pattern in saltation and stasis growth dynamics. | The serial data from two siblings, aged 6.6 and 7.5 years of age at the initiation of the study, measured each evening for total standing height during 365 days, are analysed by two methods to investigate the nature of the underlying growth pattern. The saltation and stasis model, designed to identify the presence of s... | ['Algorithms', 'Analysis of Variance', 'Anthropometry', 'Biometry', 'Body Height', 'Child', 'Data Interpretation, Statistical', 'Female', 'Growth', 'Humans', 'Male', 'Models, Biological', 'Time Factors'] | 9,624,460 | [['G17.035', 'L01.224.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E05.318.740.225', 'N06.850.505.200'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['M01.060.406'], ['E05.245.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Modification of the alpha 1-antitrypsin phenotype in neonatal hepatitis. | Two cases of neonatal hepatitis are described, one related to cytomegalovirus infection and the other idiopathic. In both infants a transient abnormality of the alpha 1-antitrypsin phenotype, inconsistent with the parent's phenotypes, reverted to normal during the convalescent phase of the illness. | ['Female', 'Hepatitis', 'Humans', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Male', 'Phenotype', 'alpha 1-Antitrypsin Deficiency'] | 3,873,914 | [['C06.552.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614.521'], ['G05.695'], ['C06.552.074', 'C08.381.112', 'C16.320.060', 'C23.550.325.500.500']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The veterinary surgeon as an actor of public health: Example of the canine leishmaniosis, a vector-borne zoonosis. | Canine leishmaniosis is an anthropozoonosis of increasing importance in which dogs are the main reservoir and source of parasites (Leishmania infantum Nicolle, 1908) for humans and for other dogs. Both diagnosis and treatment of the disease are difficult. The easy movement of dogs from endemic areas into safe areas is ... | ['Animals', 'Disease Reservoirs', 'Dog Diseases', 'Dogs', 'Humans', 'Leishmaniasis', 'Public Health', 'Vaccination', 'Veterinarians', 'Zoonoses'] | 29,901,892 | [['B01.050'], ['N06.850.520.203.250'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.300.500', 'C01.610.858.560', 'C01.920.813', 'C17.800.838.775.560'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.... | ['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council. | UNLABELLED: Most patients who undergo surgical procedures experience acute postoperative pain, but evidence suggests that less than half report adequate postoperative pain relief. Many preoperative, intraoperative, and postoperative interventions and management strategies are available for reducing and managing postope... | ['Humans', 'Pain Management', 'Pain, Postoperative', 'Practice Guidelines as Topic', 'Societies, Medical'] | 26,827,847 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.745', 'N04.590.607.500'], ['C23.550.767.700', 'C23.888.592.612.832'], ['N04.761.700.350.650', 'N05.700.350.650'], ['N03.540.828.589']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The mechanism of breathing under the conditions of prolonged voluntary hyperventilation]. | Effects of voluntary hyperventilation (2 h, 70-80% of maximal lung ventilation) on external breathing, gas exchange and blood circulation were studied in 12 healthy male volunteers. Hyperventilation was shown to change structure of the respiratory cycle as variation and expiration time were decreased. Indices of the ex... | ['Adult', 'Biomechanical Phenomena', 'Humans', 'Hypercapnia', 'Hyperventilation', 'Male', 'Middle Aged', 'Oxygen Consumption', 'Pulmonary Ventilation', 'Respiratory Physiological Phenomena', 'Time Factors'] | 10,399,551 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['C08.618.501', 'C23.888.852.591'], ['M01.060.116.630'], ['G03.680'], ['E01.370.386.700.660', 'G09.772.650'], ['G09.772'], ['G01.910.857']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Role of intraoperative fibrinolytic therapy in acute arterial occlusion. | Nineteen patients with acute onset of ischemia affecting the lower extremities were studied from January 1985 to March 1987. Patients with preoperative Doppler and angiographic studies consistent with arterial occlusions subsequently underwent a thromboembolectomy using a Fogarty catheter. All patients were given a bol... | ['Acute Disease', 'Adult', 'Aged', 'Catheterization', 'Combined Modality Therapy', 'Female', 'Heparin', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Radiography', 'Streptokinase', 'Thromboembolism', 'Ultrasonography'] | 3,041,635 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['E02.148', 'E05.157'], ['E02.186'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['E01.370.350.700'], ['D08.811.277.656.300.775', 'D12.776.124.125.662.537'], ['C14.907.355.590'], ['E01.370.350... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Metabolic syndrome in HIV-infected patients with favorable response to antiretroviral therapy]. | AIM: The assessment of the metabolic syndrome prevalence, as defined by the American Heart Association/The US National Cholesterol Education Program Adult Treatment Panel, (AHA/NCEP III updated), has been made in 68 polyexperimented HIV infected patients that received antiretroviral therapy over 24 months and who have ... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Antiretroviral Therapy, Highly Active', 'Cohort Studies', 'Cross-Sectional Studies', 'Female', 'HIV Infections', 'Humans', 'Male', 'Metabolic Syndrome', 'Prevalence', 'Risk Factors', 'Romania'] | 22,046,786 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['E02.319.310.075'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.36... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Lactic acid bacteria diversity in fermented cabbage estimated by culture-dependent and-independent methods]. | OBJECTIVE: To study the diversity of lactic acid bacteria (LAB) and dominant LAB in fermented cabbage.METHODS: Culture-dependent and -independent (16S rRNA gene clone libraries were constructed) methods were used to determine the composition of LAB in fermented cabbage.RESULTS: Ninety LAB isolated from fermented cabbag... | ['Brassica', 'Fermentation', 'Food Microbiology', 'Lactobacillus', 'Leuconostoc', 'Pediococcus', 'Phylogeny', 'Polymerase Chain Reaction', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA'] | 19,623,964 | [['B01.650.940.800.575.912.250.157.200'], ['G02.111.158.249', 'G03.191.249'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['B03.353.750.475.450', 'B03.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Expression of bFGF, VEGF and c-met and their correlation with microvessel density and progression in prostate carcinoma. | BACKGROUND: Previously, we found angiogenesis measured as microvessel density (MVD) to be associated with both pathological stage and clinical outcome after radical prostatectomy (RP). In addition, we have shown that Vascular Endothelial Growth Factor (VEGF) is one of the important inducers of angiogenesis in prostate ... | ['Factor VIII', 'Fibroblast Growth Factor 2', 'Humans', 'Immunohistochemistry', 'Male', 'Neoplasm Staging', 'Neovascularization, Pathologic', 'Paraffin Embedding', 'Prostatic Neoplasms', 'Proto-Oncogene Proteins c-met', 'Vascular Endothelial Growth Factor A'] | 15,274,358 | [['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of Immunosuppression on T-Helper 2 and B-Cell Responses to Influenza Vaccination. | BACKGROUND: Influenza vaccine immunogenicity is suboptimal in immunocompromised patients. However, there are limited data on the interplay of T- and B- cell responses to vaccination with simultaneous immunosuppression.METHODS: We collected peripheral blood mononuclear cells from transplant recipients before and 1 month... | ['Adult', 'Aged', 'B-Lymphocytes', 'Female', 'Flow Cytometry', 'Humans', 'Immunosuppressive Agents', 'Influenza Vaccines', 'Male', 'Middle Aged', 'Models, Theoretical', 'Th2 Cells', 'Transplant Recipients', 'Young Adult'] | 25,589,334 | [['M01.060.116'], ['M01.060.116.100'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Allele-specific PCR assay to genotype SNP rs7903146 in TCF7L2 gene for rapid screening of diabetes susceptibility. | OBJECTIVE: The aim of the present study is to validate a rapid and simple allele-specific PCR that genotypes TCF7/L2 rs7903146 (C/T) polymorphism with standard PCR instruments.METHODS: Two forward primers with variations in their 3' nucleotides were designed in such a way that each was specific for one of the two varia... | ['Adult', 'Alleles', 'DNA Primers', 'Diabetes Mellitus, Type 2', 'Female', 'Genetic Predisposition to Disease', 'Genetic Testing', 'Genotype', 'Humans', 'Male', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'TCF Transcription Factors', 'Transcription Factor 7-Like 2 Protein'] | 19,169,495 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['C18.452.394.750.149', 'C19.246.300'], ['C23.550.291.687.500', 'G05.380.355'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['G05.380'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Interactive typology in depression according to cognitive theory and systemic theory. | Both systemic and cognitive theories agree upon the importance of early learning in the development of depressive personality. The two theories disagree upon the meaning they give to the early experiences. According to cognitive theory the emotions bound to a significant and not reparable loss turn themselves into a pu... | ['Adult', 'Child', 'Classification', 'Cognitive Behavioral Therapy', 'Depression', 'Emotions', 'Family', 'Helping Behavior', 'Humans', 'Interpersonal Relations', 'Learning', 'Parent-Child Relations', 'Psychological Theory', 'Social Environment'] | 1,476,346 | [['M01.060.116'], ['M01.060.406'], ['L01.100', 'L01.453.245.275'], ['F04.754.137.350'], ['F01.145.126.350'], ['F01.470'], ['F01.829.263', 'I01.880.853.150'], ['F01.145.813.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.425', 'F02.784.629.529'], ['F01.829.263.370.290'], ['F02.739'], [... | ['Named Groups [M]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function. | The sterol sensor SCAP is a key regulator of SREBP-2, the major transcription factor controlling cholesterol synthesis. Recently, we showed that there is a global down-regulation of cholesterol synthetic genes, as well as SREBP-2, in the brains of diabetic mice, leading to a reduction of cholesterol synthesis. We now s... | ['Animals', 'Brain', 'Cholesterol', 'Cognition', 'Diabetes Mellitus, Experimental', 'Excitatory Postsynaptic Potentials', 'Gene Deletion', 'Haploinsufficiency', 'Hippocampus', 'Injections, Intraventricular', 'Insulin', 'Intracellular Signaling Peptides and Proteins', 'Male', 'Membrane Proteins', 'Mice', 'Mice, Inbred C... | 23,585,733 | [['B01.050'], ['A08.186.211'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['F02.463.188'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G05.365.590.762.320', '... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A high degree of HLA disparity arises from limited allelic diversity: analysis of 1775 unrelated bone marrow transplant donor-recipient pairs. | The allelic diversity and associated human leukocyte antigen (HLA) disparity of 1775 bone marrow recipients and their unrelated donors, matched for six of six (1361/1775,77%), five of six (397/1775, 22%), or four of six (17/1775, 1%) HLA-A, -B, -DR antigens, were retrospectively evaluated. The comprehensive HLA analysi... | ['Alleles', 'Bone Marrow Transplantation', 'Genetic Variation', 'HLA Antigens', 'HLA-D Antigens', 'Histocompatibility Antigens Class I', 'Histocompatibility Testing', 'Humans', 'Retrospective Studies', 'Tissue Donors'] | 17,207,710 | [['G05.360.340.024.340.030'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G05.365'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.509.400', 'D12.776.543.550.440.400', 'D23.050.301.500.400.400', 'D23.050.301.500.450.400', 'D23.050.705.552.410.400', 'D23.050.705.552.450.400'], ['D12.776.395.550.489... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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