Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Release by vasopression of E-type prostaglandins from the rate kidney. | 1. In order to test whether the release of E-type prostaglandins from the kidney by various vasoconstrictor stimuli is related specifically to adrenoreceptor activation, we have compared release of prostaglandin E-like material from perfused rat kidneys during infusion of noradrenaline or vasopressin. 2. Concentrations... | ['Animals', 'Female', 'Kidney', 'Male', 'Norepinephrine', 'Prostaglandins E', 'Rats', 'Vasopressins'] | 606,458 | [['B01.050'], ['A05.810.453'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['D10.251.355.255.550.250', 'D23.469.050.175.725.250'], ['B01.050.150.900.649.313.992.635.505.700'], ['D06.472.699.631.692.781', 'D12.644.400.900', 'D12.644.456.925... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gastroesophageal reflux disease as a likely cause of "idiopathic" subglottic stenosis. | The cause of subglottic stenosis (SGS) is unknown for a subgroup of patients in which there is a female predominance. Seven women ranging in age from 39 to 66 years developed symptomatic and progressive SGS. Six of the 7 patients failed to respond to all measures of conservative and radical surgical intervention. After... | ['Adult', 'Aged', 'Diagnosis, Differential', 'Female', 'Gastroesophageal Reflux', 'Glottis', 'Humans', 'Laryngostenosis', 'Middle Aged', 'Retrospective Studies'] | 8,122,834 | [['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['C06.405.117.119.500.484'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.360.591', 'C09.400.591', 'C16.131.740.658'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.33... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pyruvate metabolism after in vivo exposure to oral arsenic. | This study investigated altered pyruvate metabolism after prolonged oral arsenic exposure. Male rats were given access to deionized drinking water containing 0, 40 or 85 ppm sodium arsenate (As5+) for 3 weeks. Respiration studies with mitochondria isolated from treated animals indicated decreased state 3 respiration (w... | ['Animals', 'Arsenic', 'Male', 'Mitochondria, Liver', 'Oxidation-Reduction', 'Proteins', 'Pyruvate Dehydrogenase Complex', 'Pyruvates', 'Rats', 'Succinates', 'Time Factors'] | 688,523 | [['B01.050'], ['D01.268.513.249'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['G02.700', 'G03.295.531'], ['D12.776'], ['D05.500.562.625', 'D08.811.600.741'], ['D02.241.755.812'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.241.081.337.759'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oral supplementations with L-glutamine or L-alanyl-L-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance. | In this work, we aimed to investigate the effects of long-term supplementations with L-glutamine or L-alanyl-L-glutamine in the high-fat diet (HFD)-fed B6.129SF2/J mouse model over insulin sensitivity response and signaling, oxidative stress markers, metabolism and HSP70 expression. Mice were fed in a standard low-fat ... | ['Administration, Oral', 'Animals', 'Diet, High-Fat', 'Disease Models, Animal', 'Glutamine', 'Insulin Resistance', 'Mice'] | 26,530,165 | [['E02.319.267.100'], ['B01.050'], ['G07.203.650.240.267'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.125.068.330', 'D12.125.095.461', 'D12.125.154.424'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['B01.050.150.900.649.313.992.635.505.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunophenotypic and genotypic markers of follicular center cell neoplasia in diffuse large B-cell lymphomas. | Diffuse large B-cell lymphomas (DLBCL) are a biologically and clinically heterogeneous entity. Although some DLBCL represent transformation of follicular lymphomas (FL), the proportion that is of follicular center cell (FCC) origin remains uncertain. Immunophenotypic and genotypic markers used to suggest a FCC origin f... | ['B-Lymphocytes', 'Biomarkers, Tumor', 'DNA, Neoplasm', 'DNA-Binding Proteins', 'Flow Cytometry', 'Genetic Markers', 'Humans', 'Immunoenzyme Techniques', 'Immunophenotyping', 'Lymphoma, Large B-Cell, Diffuse', 'Membrane Glycoproteins', 'Neprilysin', 'Proteoglycans', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c... | 11,106,080 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D23.101.140'], ['D13.444.308.425'], ['D12.776.260'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.36... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sinus histiocytosis with massive lymphadenopathy in a Japanese male with symptoms of dyspnea and visual disturbance. | A case study of sinus histiocytosis with massive lymphadenopathy is reported. A Japanese male developed lymphadenopathy in the nasal cavity 10 years ago. Biopsy specimens demonstrated massive histiocytosis with phagocytosis of lymphocytes, plasmacytes, and erythrocytes. During the course of his illness, the patient exp... | ['Adult', 'Dyspnea', 'Epistaxis', 'Histiocytosis, Sinus', 'Humans', 'Lymphatic Diseases', 'Male', 'Nasal Obstruction', 'Nose Diseases', 'Vision Disorders'] | 2,222,334 | [['M01.060.116'], ['C08.618.326', 'C23.888.852.371'], ['C08.460.261', 'C09.603.261', 'C23.550.414.712', 'C23.888.852.040'], ['C15.604.250.410.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604'], ['C08.460.525', 'C08.618.846.185.525', 'C09.603.525'], ['C08.460', 'C09.603'], ['C10.597.751.941', 'C11.966',... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of pH on the stability and structure of yeast hexokinase A. Acidic amino acid residues in the cleft region are critical for the opening and the closing of the structure. | pH and salts have a marked effect on the stability, structure, and function of many globular proteins due to their ability to influence the electrostatic interactions. In this work, calorimetry, CD, and fluorescence studies have been carried out to understand the pH-dependent conformational changes of the two-domain pr... | ['Acids', 'Amino Acids', 'Calorimetry', 'Circular Dichroism', 'Crystallography, X-Ray', 'Fungal Proteins', 'Hexokinase', 'Hydrogen-Ion Concentration', 'Protein Conformation', 'Protein Folding', 'Protein Structure, Tertiary', 'Sodium Chloride', 'Spectrometry, Fluorescence', 'Static Electricity', 'Temperature'] | 15,145,950 | [['D01.029'], ['D12.125'], ['E05.196.131'], ['E05.196.867.151'], ['E05.196.309.742.225'], ['D12.776.354'], ['D08.811.913.696.620.300'], ['G02.300'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.610'], ['D01.210.450.150.875', 'D01.857.650'], ['E05.196.712.516.600.676', 'E05.196.867.726'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Approval of courses in new skills. | The Committee on Emerging Surgical Technologies has previously published "Guidelines for Evaluation of Credentials of Individuals for the Purpose of Awarding Surgical Privileges in New Technologies." In that statement, which was approved by the American College of Surgeons' Board of Regents and published in 1994, the c... | ['Curriculum', 'Education, Medical, Continuing', 'General Surgery', 'Medical Staff Privileges', 'Organizational Policy', 'Societies, Medical', 'Surgical Procedures, Operative', 'United States'] | 10,177,927 | [['I02.158'], ['I02.358.212.350', 'I02.358.399.250'], ['H02.403.810.300'], ['N02.278.216.500.996.500', 'N04.452.442.452.530.500', 'N04.452.758.275.500'], ['I01.655.500.550', 'I01.880.604.825.550', 'N03.623.500.550'], ['N03.540.828.589'], ['E04'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Allostatic load in an environmental riskscape: the role of stressors and gender. | Stressors are theorized to be associated with higher allostatic load (AL), a concept of physiological wear measured as a composite of physical biomarkers. Risk of high AL may vary by gender and may be intensified in places with significant environmental risks, otherwise known as 'environmental riskscapes'. Yet, no stud... | ['Adult', 'Aged', 'Aged, 80 and over', 'Allostasis', 'Environmental Exposure', 'Female', 'Health Status Disparities', 'Humans', 'Male', 'Middle Aged', 'Sex Factors', 'Stress, Physiological', 'Texas'] | 21,543,249 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G16.012.500.274'], ['N06.850.460.350'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875'], ['G07.775'], ['Z01.107.567.875.760.75... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Coextraction of thrombomodulin and tissue factor from human placenta: effects of concanavalin A and phospholipid environment on activity. | Thrombomodulin and tissue factor activities have been co-extracted from human placenta by several non-ionic detergents, n-octylglucoside and Triton X-100 being the most efficient ones. The n-octylglucoside placenta extract had a strong cofactor activity in the activation of human protein C by human alpha-thrombin. Trea... | ['Female', 'Glucosides', 'Glycoproteins', 'Humans', 'In Vitro Techniques', 'Kinetics', 'Octoxynol', 'Phospholipases', 'Phospholipids', 'Placenta', 'Polyethylene Glycols', 'Pregnancy', 'Protein C', 'Receptors, Cell Surface', 'Receptors, Thrombin', 'Sepharose', 'Thromboplastin'] | 3,010,487 | [['D09.408.348'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['D02.033.455.250.700.660', 'D05.750.741.610', 'D25.720.741.610', 'J01.637.051.720.741.610'], ['D08.811.277.352.100.680', 'D08.811.277.352.640.700'], ['D10.570.755'], ['A16.710... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Human embryo fragmentation in vitro and its implications for pregnancy and implantation. | OBJECTIVE: To evaluate the effects of fragmentation and fragment removal in day 3 human embryos on implantation and pregnancy.DESIGN: Retrospective analysis of ETs homogeneous with respect to embryo fragmentation.SETTING: A program of IVF-ET.PATIENT(S): The study population consisted of 2,410 patients.INTERVENTION(S): ... | ['Adult', 'DNA Fragmentation', 'Embryo Implantation', 'Embryo, Mammalian', 'Female', 'Fertilization in Vitro', 'Humans', 'Pregnancy', 'Pregnancy Rate', 'Retrospective Studies'] | 10,231,042 | [['M01.060.116'], ['G05.200.230'], ['G08.686.784.170.104.500'], ['A16.254'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E05.318.308.985.775', 'G08.686.705', 'N01.224.935.849', 'N06.850.505.400.975.775', 'N06.850.520.308.985.775'], ['E05.318.372.500.50... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
IL-1 modifies system A transport activity in human rheumatoid synovial cells. | Given the importance of interleukin-1 in both rheumatic diseases and the modulation of cell metabolic activities, we studied the action of this cytokine on the neutral amino acid transport A system on rheumatoid synovial cells. In these cells IL-1 (1 ng/ml) induced amino transport stimulation from 5 min to 5 h. This ef... | ['Amino Acids', 'Arthritis, Rheumatoid', 'Biological Transport', 'Cycloheximide', 'Humans', 'Interleukin-1', 'Protein Biosynthesis', 'Protein Synthesis Inhibitors', 'Synovial Membrane', 'beta-Alanine'] | 9,313,345 | [['D12.125'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G03.143'], ['D03.383.621.808.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Body fat distribution in perinatally HIV-infected and HIV-exposed but uninfected children in the era of highly active antiretroviral therapy: outcomes from the Pediatric HIV/AIDS Cohort Study. | BACKGROUND: Associations between abnormal body fat distribution and clinical variables are poorly understood in pediatric HIV disease.OBJECTIVE: Our objective was to compare total body fat and its distribution in perinatally HIV-infected and HIV-exposed but uninfected (HEU) children and to evaluate associations with cl... | ['Absorptiometry, Photon', 'Adipose Tissue', 'Adolescent', 'Age Factors', 'Antiretroviral Therapy, Highly Active', 'Body Fat Distribution', 'Body Height', 'Body Mass Index', 'Body Weight', 'Child', 'Continental Population Groups', 'Female', 'HIV Infections', 'HIV Seropositivity', 'Humans', 'Infectious Disease Transmiss... | 22,049,166 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['A10.165.114'], ['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['E02.319.310.075'], ['E01.370.600.115.100.062', 'G02.111.130.134', 'G03.180.134', 'G07.100.049.134'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of a disaccharide fragment of rhamnogalacturonan II. | A disaccharide portion of the A-side chain of the rhamnogalacturonan II oligosaccharide has been prepared. Glycosylation of methyl (methyl 3,4-O-isopropylidene-alpha-D-galactopyranosid)uronate with p-tolyl 2,3-di-O-acetyl-3-C-(benzyloxymethyl)-1-thio-alpha/beta-D-erythrofuranoside was carried out using N-iodosuccinimid... | ['Carbohydrate Conformation', 'Carbohydrate Sequence', 'Cell Wall', 'Disaccharides', 'Glycosylation', 'Pectins', 'Plants'] | 15,476,711 | [['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['A11.284.183'], ['D09.698.629.305', 'D09.947.750'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['D05.750.078.738', 'D09.698.670', 'D20.215.784.500.618'], ['B01.650']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Serum total and high-density lipoprotein phospholipids: independent predictive value for cardiometabolic risk. | OBJECTIVE: Given that serum phospholipids (PL) may serve as inflammation mediators, we studied whether they predicted metabolic syndrome (MetS), type-2 diabetes or coronary heart disease (CHD) risk in people prone to enhanced low-grade inflammation.METHODS: We analyzed unselected middle-aged Turkish adults with availab... | ['Apolipoproteins', 'Cardiovascular Diseases', 'Cholesterol, HDL', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Humans', 'Logistic Models', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Phospholipids', 'Predictive Value of Tests', 'Proportional Hazards Models', 'Risk Factors', 'Turkey', 'Uric Acid', 'Wa... | 24,246,837 | [['D10.532.091', 'D12.776.070.400', 'D12.776.521.120'], ['C14'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Regional Fluctuation in the Functional Consequence of LINE-1 Insertion in the Mitf Gene: The Black Spotting Phenotype Arisen from the Mitfmi-bw Mouse Lacking Melanocytes. | Microphthalmia-associated transcription factor (Mitf) is a key regulator for differentiation of melanoblasts, precursors to melanocytes. The mouse homozygous for the black-eyed white (Mitfmi-bw) allele is characterized by the white-coat color and deafness with black eyes due to the lack of melanocytes. The Mitfmi-bw al... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'Cyclin D1', 'Hair Follicle', 'Keratinocytes', 'Long Interspersed Nucleotide Elements', 'Melanocytes', 'Mice', 'Microphthalmia-Associated Transcription Factor', 'Phenotype', 'beta Catenin'] | 26,930,598 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['A11.409.500', 'A11.436.397'], ['G02.111.570.080.708.330.800.400', 'G05.360.080.708.330... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maternal depression and child behaviour problems: a meta-analysis. | Children of depressed mothers are not only at risk for the development of psychopathology, but also for behaviour problems. A meta-analysis of 33 studies was conducted to determine the magnitude of the relationship between maternal depression and behaviour problems in children 1 year of age and older. Substantive, meth... | ['Adolescent', 'Child', 'Child Behavior Disorders', 'Child of Impaired Parents', 'Child, Preschool', 'Depressive Disorder', 'Female', 'Humans', 'Infant'] | 10,210,459 | [['M01.060.057'], ['M01.060.406'], ['F03.625.141'], ['M01.106'], ['M01.060.406.448'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Serosurvey of ex situ giant pandas (Ailuropoda melanoleuca) and red pandas (Ailurus fulgens) in China with implications for species conservation. | Conservation strategies for the giant panda (Ailuropoda melanoleuca) include the development of a self-sustaining ex situ population. This study examined the potential significance of infectious pathogens in giant pandas ex situ. Serologic antibody titers against canine distemper virus (CDV), canine parvovirus (CPV), c... | ['Animals', 'Antibodies, Bacterial', 'Antibodies, Protozoan', 'Antibodies, Viral', 'China', 'Conservation of Natural Resources', 'Female', 'Male', 'Population Surveillance', 'Seroepidemiologic Studies', 'Serologic Tests', 'Ursidae', 'Vaccination'] | 18,229,861 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['Z01.252.474.164'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Outpatient pediatric dermatologic surgery: experience in 296 patients. | From January 2010 to December 2012, 296 skin biopsies were performed in pediatric patients using only local anesthesia (cream and infiltration). The biopsies were divided into three groups: biopsies of skin neoplasms, biopsies of skin rashes and biopsies of follicular-centered lesions. Our data demonstrate the possibil... | ['Adolescent', 'Ambulatory Care Facilities', 'Biopsy', 'Child', 'Child, Preschool', 'Dermatologic Surgical Procedures', 'Female', 'Humans', 'Infant', 'Male', 'Skin Diseases', 'Treatment Outcome'] | 25,490,940 | [['M01.060.057'], ['N02.278.035'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['M01.060.406'], ['M01.060.406.448'], ['E04.680.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C17.800'], ['E01.78... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Decelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes. | Vertebrates diverged from other chordates ~500 Myr ago and experienced successful innovations and adaptations, but the genomic basis underlying vertebrate origins are not fully understood. Here we suggest, through comparison with multiple lancelet (amphioxus) genomes, that ancient vertebrates experienced high rates of ... | ['Adaptation, Physiological', 'Animals', 'DNA Transposable Elements', 'Evolution, Molecular', 'Exons', 'Genome', 'Lancelets', 'Vertebrates'] | 25,523,484 | [['G07.025', 'G16.012.500'], ['B01.050'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.137.232'], ['G05.360.340'], ['B01.050.150.200.199.500', 'B01.050.500.272.199.500'], ['B01.050.150.900']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relapsing inappropriate antidiuretic hormone secretion in an anti-aquaporin-4 antibody positive paediatric patient. | Paediatric patients with the syndrome of an inappropriate antidiuretic hormone secretion (SIADH), as a manifestation of inflammatory demyelinating disorders of the central nervous system, have been rarely described until now, in only a few cases of neuromyelitis optica spectrum disorders (NMOSDs). We present a case of ... | ['Adolescent', 'Aquaporin 4', 'Autoantibodies', 'Biomarkers', 'Female', 'Fluid Therapy', 'Humans', 'Immunoglobulin G', 'Immunosuppressive Agents', 'Inappropriate ADH Syndrome', 'Magnetic Resonance Imaging', 'Neuromyelitis Optica', 'Predictive Value of Tests', 'Recurrence', 'Serologic Tests', 'Treatment Outcome'] | 24,866,202 | [['M01.060.057'], ['D12.776.157.530.400.500.040.468', 'D12.776.543.550.450.730.040.468', 'D12.776.543.585.400.730.040.577'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.101'], ['E02.319.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Engagement with meditation as a positive health trajectory: divergent narratives of progress in male meditators. | OBJECTIVE: Studying personal narratives can generate understanding of how people experience physical and mental illness. However, few studies have explored narratives of engagement in health positive behaviours, with none focusing on men specifically. Thus, we sought to examine men's experiences of their efforts to eng... | ['Adult', 'Attitude to Health', 'Health Behavior', 'Humans', 'Male', 'Meditation', 'Middle Aged', 'Narration', 'Young Adult'] | 24,102,199 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.374', 'E02.190.901.455', 'F04.754.137.750.500'], ['M01.060.116.630'], ['E05.318.308.502', 'F01.145.209.459', 'L01.399.250.660', 'N05.715.360.300.480', 'N06.850.520.308.502'], ['M01.060.116.8... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The Value of Preoperative Volumetric Analysis by Computerised Tomography of Retrosternal Goiter to Predict the Need for an Extra-Cervical Approach. | BACKGROUND: A thyroidectomy can be performed via a cervical incision in most patients with retrosternal goiter.AIMS: To investigate the correlation between the volume of the mediastinal portion of the thyroid gland and the need for an extra-cervical approach for retrosternal goiter.STUDY DESIGN: Diagnostic accuracy stu... | ['Aged', 'Female', 'Goiter, Substernal', 'Humans', 'Male', 'Middle Aged', 'ROC Curve', 'Risk Assessment', 'Sternotomy', 'Thyroidectomy'] | 28,840,845 | [['M01.060.116.100'], ['C19.874.283.601'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of prenatal exposure to Zidovudine and Lamivudine on brainstem auditory evoked potentials in infants from HIV-infected women. | Long-term in utero adverse effects of infants exposed perinatally to antiretroviral drugs are still unknown. The purpose of this study was to determine whether there were differences in Brainstem Auditory Evoked Potential (BAEP) waves and interval interwaves in a group of Zidovudine (AZT) alone or AZT plus Lamivudine (... | ['Adult', 'Anti-HIV Agents', 'Apgar Score', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'HIV Infections', 'Humans', 'Infant, Newborn', 'Lamivudine', 'Pregnancy', 'Reverse Transcriptase Polymerase Chain Reaction', 'Zidovudine'] | 15,633,610 | [['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E01.370.600.050'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The epileptic singers of belle ?poque Paris. | In late 19th century Paris, people with epilepsy were treated alongside those with hysteria in the now famous Salp?tri?re Hospital, where both conditions were deemed to have a neurological basis. When Jean Martin Charcot became chief physician at the Salp?tri?re Hospital in 1862, he described himself 'in possession of ... | ['Epilepsy', 'History, 19th Century', 'Hospitals', 'Humans', 'Hysteria', 'Museums', 'Music', 'Neurology', 'Paris', 'Singing'] | 22,613,757 | [['C10.228.140.490'], ['K01.400.504.937'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.675.400.500'], ['J03.570', 'K01.400.152.552'], ['K01.602'], ['H02.403.600'], ['Z01.433.800', 'Z01.542.286.588'], ['G09.772.585.500']] | ['Diseases [C]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Neurohumoral hypothesis of motion-induced vomiting. Communication. | The current status and implications of the neurohumoral hypothesis of motion-induced vomiting are reviewed. Data show that squirrel monkey subjects vomit only once if horizontal rotation is terminated immediately on the occurrence of the emetic response. Refractory periods for multiple vomiting episodes concurrent with... | ['Animals', 'Cerebral Ventricles', 'Chemoreceptor Cells', 'Motion Sickness', 'Neurotransmitter Agents', 'Saimiri', 'Vomiting'] | 2,861,784 | [['B01.050'], ['A08.186.211.140'], ['A08.675.650.915.500', 'A08.800.950.500', 'A11.671.650.915.500'], ['C23.888.571'], ['D27.505.519.625', 'D27.505.696.577'], ['B01.050.150.900.649.313.988.400.600.150.710.710'], ['C23.888.821.937']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rare complication of Q fever vaccination. | A 32-year-old woman with a past history of malignant melanoma presented with a lump in the upper left arm that was excised. Histological examination revealed a granulomatous dermatitis and panniculitis that proved to be a rare reaction to Q fever vaccination. | ['Adult', 'Bacterial Vaccines', 'Coxiella burnetii', 'Diagnosis, Differential', 'Female', 'Granuloma, Foreign-Body', 'Humans', 'Melanoma', 'Panniculitis', 'Q Fever', 'Skin Neoplasms'] | 15,842,410 | [['M01.060.116'], ['D20.215.894.135'], ['B03.440.400.425.297.150.100', 'B03.660.250.132.150.100'], ['E01.171'], ['C23.550.382.437', 'C26.392.560.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['C17.300.710', 'C17.800.566'], ['C01.150.25... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of B-type cyclins in the smut fungus Ustilago maydis: roles in morphogenesis and pathogenicity. | Pathogenesis, morphogenesis and cell cycle are connected in the fungal pathogen Ustilago maydis. Here we report the characterization of the catalytic subunit of the cyclin-dependent kinase, encoded by the gene cdk1, and the two B-type cyclins present in this organism, encoded by the genes clb1 and clb2. These cyclins a... | ['Amino Acid Sequence', 'Cloning, Molecular', 'Cyclin B', 'G1 Phase', 'G2 Phase', 'Mitosis', 'Molecular Sequence Data', 'S Phase', 'Ustilago', 'Virulence'] | 14,679,309 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['D12.644.360.262.120', 'D12.776.167.218.120', 'D12.776.476.262.120'], ['G04.144.500.320'], ['G04.144.500.340'], ['G04.144.220.220.781', 'G05.113.220.781'], ['L01.453.245.667'], ['G02.111.225.880', 'G04.144.500.800', 'G05.226.880'], ['B01.300.179.853.800'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A behavioral genetic investigation of weekend drinking among an adult sample. | This study examined common and unique genetic and environmental influences on weekend drinking and weekday drinking reported by US male and female adult participants (mean age = 43.9). Data from 96 monozygotic and 82 dizygotic twin pairs were used to estimate bivariate biometric models of daily levels of weekend and we... | ['Adult', 'Alcohol Drinking', 'Female', 'Gene-Environment Interaction', 'Humans', 'Male', 'Models, Biological', 'Social Control, Informal', 'Time Factors', 'Twins, Dizygotic', 'Twins, Monozygotic'] | 23,421,388 | [['M01.060.116'], ['F01.145.317.269'], ['G05.695.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['I01.880.630'], ['G01.910.857'], ['M01.438.873.920'], ['M01.438.873.940']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Antigenic characteristics of five species of human Bacteroides. | The antigenic characteristics of five species of Bacteroides were determined by agglutination tests. No cross-reactivity among the species was observed. | ['Agglutination Tests', 'Antigens', 'Bacteroides'] | 5,359,613 | [['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['D23.050'], ['B03.440.080.094.152', 'B03.440.425.410.194.152']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of a beta thalassemia gene with abnormal splicing. | Expression of a cloned human beta thalassemia gene with a single base change at position 5 of IVS 1 has been analyzed 48 hours after transfer of the gene into HeLa cells (transient expression). Little or no normal beta globin mRNA accumulates in the presence of the abnormal beta gene in contrast to significantly more n... | ['Base Sequence', 'Cloning, Molecular', 'DNA, Recombinant', 'Exons', 'Genes', 'Globins', 'HeLa Cells', 'Hemoglobin A', 'Humans', 'Molecular Sequence Data', 'Phenotype', 'RNA, Messenger', 'Thalassemia', 'Transcription, Genetic'] | 3,671,081 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.460'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340'], ['D12.776.422.316'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D12.776.124.400.405', 'D12.776.422.316.762.380'], ['B01.050.150.900.649.313.98... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Maintain a safe environment of care. | Learn the latest updates to JCAHO's environment of care standards. | ['Emergencies', 'Fires', 'Hospital Administration', 'Humans', 'Joint Commission on Accreditation of Healthcare Organizations', 'Quality Indicators, Health Care', 'Safety Management', 'Security Measures', 'United States'] | 15,644,710 | [['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['N06.230.216'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.110.070.410', 'N05.700.200.100.420'], ['N04.761.789', 'N05.715.760'], ['N04.452.871.900', 'N06.850.135.060.075.800'], ['N04.452.910'], ['... | ['Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Informational and emotional daily messages to reduce red and processed meat consumption. | In the present study we tested a daily messaging intervention aimed at promoting the reduction of red and processed meat consumption (RPMC). We randomly allocated 180 young adults to three different message conditions. Participants in the informational condition read messages on the consequences of excessive RPMC on on... | ['Attitude', 'Behavior Therapy', 'Diet', 'Emotions', 'Feeding Behavior', 'Female', 'Humans', 'Intention', 'Male', 'Meat', 'Text Messaging', 'Young Adult'] | 31,276,710 | [['F01.100'], ['F04.754.137'], ['G07.203.650.240'], ['F01.470'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['G07.203.300.600', 'J02.500.600'], ['L01.178.847.698.300.500', 'L01.559.423.906.377.666'], ['M01.060.116.815']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Individual cell sorting. | Current cell sorting machines do not preserve the individual identity of processed cells; after analysis, the cells are assigned to a subpopulation where they are pooled with other similar cells. This paper reports progress on a system that sorts cells individually to precise locations on a microscope slide and preserv... | ['Animals', 'Cell Separation', 'Cytological Techniques', 'Humans', 'Lymphocytes', 'Mice', 'Microscopy, Fluorescence', 'Microspheres', 'Models, Biological'] | 374,588 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prostaglandin synthesis and metabolism in the human uterus and midtrimester fetal tissues. | Prostaglandin (PG) synthesis and metabolism was studied in human fetal kidney, lung, small intestine, heart, brain and liver (gestational ages: 10, 12, 14, 18 and 23 weeks) and pregnant uterus (4-40 weeks of pregnancy). PG synthesis was increased in the myometrium during pregnancy while the capacity of metabolism did n... | ['Female', 'Fetus', 'Gestational Age', 'Humans', 'Hydroxyprostaglandin Dehydrogenases', 'Myometrium', 'Pregnancy', 'Pregnancy Trimester, Second', 'Prostaglandin-Endoperoxide Synthases', 'Prostaglandins', 'Uterus'] | 6,776,273 | [['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.047.820.375'], ['A02.633.570.500', 'A05.360.319.679.690', 'A10.690.467.500'], ['G08.686.784.769'], ['G08.686.707.490'], ['D08.811.600.720', 'D08.811.682.690.708.715'], ['D10.251.355.255.550', 'D23.46... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The prognostic significance of the ultrastructural characteristics of human rectal cancer]. | A retrospective study of the ultrastructure of rectal tumors in patients with favorable and unfavorable prognosis was undertaken. It established favorable postoperative course and prognosis in tumors containing more than half undifferentiated cells. Conversely, tumors in which malignant cells with electron microscopy-i... | ['Adenocarcinoma', 'Adult', 'Aged', 'Female', 'Humans', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Organelles', 'Prognosis', 'Rectal Neoplasms', 'Rectum', 'Retrospective Studies'] | 2,815,693 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630'], ['A11.284.430.214.190.875'], ['E01.789'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.405.469.491.3... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Diversity of virulence profiles of Shiga toxin-producing Escherichia coli serotypes in food-producing animals in Brazil. | The prevalence, serotypes and virulence profiles of Shiga toxin-producing Escherichia coli (STEC) were investigated in 205 healthy beef and dairy cattle, and 106 goats reared in the southeastern region of Minas Gerais State, Brazil. The prevalence of STEC was 57.5% (61/106) in goats, 39.2%, (40/102) in beef cattle and ... | ['Animals', 'Brazil', 'Cattle', 'Cattle Diseases', 'Disease Reservoirs', 'Escherichia coli Infections', 'Female', 'Goat Diseases', 'Goats', 'Humans', 'Male', 'Phylogeny', 'Prevalence', 'Serotyping', 'Shiga Toxins', 'Shiga-Toxigenic Escherichia coli', 'Species Specificity', 'Virulence Factors'] | 18,678,426 | [['B01.050'], ['Z01.107.757.176'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['N06.850.520.203.250'], ['C01.150.252.400.310.330'], ['C22.405'], ['B01.050.150.900.649.313.500.380.513'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.318.308.985.525.750', 'N0... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Why Should I Care? Dimensions of Socio-Emotional Cognition in Younger-Onset Dementia. | BACKGROUND: Skills such as empathy and emotion recognition rely on a multi-dimensional socio-emotional system. Increasingly, evidence suggests that socio-emotional cognition is affected in frontotemporal dementia and Alzheimer's disease (AD), to varying degrees. However, the specific dimensions of socio-emotional behav... | ['Aged', 'Alzheimer Disease', 'Cognition Disorders', 'Dementia', 'Female', 'Frontotemporal Dementia', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Mood Disorders', 'Neuropsychological Tests', 'Psychiatric Status Rating Scales', 'Social Behavior', 'Surveys and Questionnaires'] | 26,401,935 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['F03.615.250'], ['C10.228.140.380', 'F03.615.400'], ['C10.228.140.380.266.299', 'C10.574.950.300.299', 'C18.452.845.800.300.299', 'F03.615.400.380.299'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mucosal immunization of BALB/c mice with DNA vaccines encoding the SEN1002 and SEN1395 open reading frames of Salmonella enterica serovar Enteritidis induces protective immunity. | Salmonella Enteritidis is the main cause of foodborne salmonellosis worldwide. The limited effectiveness of current interventions against this pathogen has been the main incentive to develop new methods for the efficient control of this infection. To investigate the use of DNA vaccines against S. Enteritidis in humans,... | ['Adjuvants, Immunologic', 'Animals', 'Antibodies, Bacterial', 'Female', 'Immunity, Mucosal', 'Immunoglobulin G', 'Mice', 'Mice, Inbred BALB C', 'Open Reading Frames', 'Salmonella Infections, Animal', 'Salmonella Vaccines', 'Salmonella enteritidis', 'Vaccination', 'Vaccines, DNA'] | 26,113,459 | [['D27.505.696.477.067'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G12.450.573'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Physiological responses to prolonged saturation diving: a field-based pilot study. | This study aimed to assess the effect of extreme environmental exposure during an operational saturation dive on airway inflammation (exhaled nitric oxide (FeNo)), components of fitness (flexibility and aerobic capacity) and blood hematological variables. Six saturation divers, who undertook a 26±0.5 day operational sa... | ['Adult', 'Diving', 'Exhalation', 'Hematocrit', 'Hemoglobins', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Nitric Oxide', 'Oxygen Consumption', 'Physical Fitness', 'Pilot Projects', 'Respiratory Physiological Phenomena'] | 29,281,195 | [['M01.060.116'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['G09.772.705.700.275'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['M01.060.116.630'], ['D01.339.387', 'D01.625.550.50... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Gait disturbance in normal pressure hydrocephalus: a clinical study. | The origin of gait disturbance in normal pressure hydrocephalus (NPH) is poorly understood. We assessed the frequency of frontal and sub-cortical hypokinetic gait clinical features and changes in gait variables after lumbar puncture (LP), in 15 patients with idiopathic NPH. Hypokinesia and disequilibrium were the main ... | ['Aged', 'Aged, 80 and over', 'Female', 'Gait Disorders, Neurologic', 'Humans', 'Hydrocephalus, Normal Pressure', 'Male', 'Middle Aged', 'Spinal Puncture'] | 17,052,947 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.597.404', 'C23.888.592.413'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602.750'], ['M01.060.116.630'], ['E01.370.225.998.054.790', 'E01.370.376.700', 'E02.800.779', 'E04.074.790', 'E04.665.700', 'E05.200.998.054.790']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Familial lipoprotein lipase deficiency caused by known (G188E) and novel (W394X) LPL gene mutations. | Lipoprotein lipase (LPL) is the key enzyme in the catabolism of triglyceride-rich lipoproteins in the circulation. Familial LPL deficiency is characterized by hypertriglyceridaemia and absence of LPL activity. We report a case of LPL deficiency in a 43-year-old woman, who initially presented in childhood with chylomicr... | ['Adult', 'Aged', 'Amino Acids', 'Child', 'Female', 'Humans', 'Hyperlipoproteinemia Type I', 'Lipoprotein Lipase', 'Male', 'Middle Aged', 'Mutation', 'Pedigree'] | 18,275,685 | [['M01.060.116'], ['M01.060.116.100'], ['D12.125'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.398.465', 'C18.452.584.500.500.644.237', 'C18.452.648.398.465'], ['D08.811.277.352.100.430'], ['M01.060.116.630'], ['G05.365.590'], ['E05.393.673']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Toxicity of four spill-treating agents on bacterial growth and sea urchin embryogenesis. | The toxicity of spill-treating agents (STAs) is a topic that needs to be assessed prior to their potential application in environmental disasters. The aim of the present work was to study the effects of four commercial STAs (CytoSol, Finasol OSR 51, Agma OSD 569 and OD4000) on the growth of marine (Phaeobacter sp., Pse... | ['Animals', 'Bacteria', 'Biological Assay', 'Biomass', 'Embryonic Development', 'Kinetics', 'Paracentrotus', 'Water Pollutants, Chemical'] | 24,268,751 | [['B01.050'], ['B03'], ['E05.091'], ['G16.500.275.157.100', 'N06.230.124.100'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['G01.374.661', 'G02.111.490'], ['B01.050.500.408.578.600'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Monitoring of subvisible particles in therapeutic proteins. | The unintended presence of particulate matter in injectable products is an indicator of the quality of the product. Subvisible particulates have historically been monitored through methods such as light obscuration and membrane microscopy, as outlined in the United States Pharmacopeia (USP) General Chapter <788> or the... | ['Drug Contamination', 'Flow Cytometry', 'Humans', 'Microscopy', 'Particle Size', 'Proteins'] | 22,735,966 | [['N06.850.360'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['G02.712'], ['D12.776']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Results of zone II flexor tendon repair in children younger than age 6 years: botulinum toxin type A administration eased cooperation during the rehabilitation and improved outcome. | The inability of young children with a zone II flexor tendon repair to cooperate in postoperative care and rehabilitation may represent a high risk for medical and surgical complications. To forestall that risk, botulinum toxin type A (2.5 U/kg, 7 U/kg) injection was used during surgery to induce forearm flexor muscle ... | ['Botulinum Toxins, Type A', 'Child, Preschool', 'Elbow', 'Female', 'Fingers', 'Humans', 'Infant', 'Injections, Intra-Articular', 'Intraoperative Care', 'Male', 'Muscle Relaxation', 'Orthopedic Procedures', 'Postoperative Care', 'Tendon Injuries', 'Tendons', 'Treatment Outcome'] | 15,502,560 | [['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['M01.060.406.448'], ['A01.378.800.420'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.319.267.530.380'], ['E02.760.731.400', 'E04.604.249', 'N02.421... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Placental Chorionic Cyst Fluid Has Prothrombotic Properties and Differs From Amniotic Fluid. | INTRODUCTION: Chorionic cysts of the chorion laeve, fetal chorionic plate, septum, and free membranes have been associated with placental hypoxia, but they have no clear clinical significance. Although immunohistochemistry has identified fibronectin and collagen IV in cyst fluid, the contents have yet to be fully chara... | ['Amniotic Fluid', 'Chorion', 'Cyst Fluid', 'Cysts', 'Female', 'Humans', 'Placenta', 'Placenta Diseases', 'Pregnancy', 'Thrombelastography', 'Thrombosis'] | 31,033,383 | [['A12.098', 'A16.378.149'], ['A10.615.284.473', 'A16.254.750.473'], ['A12.383.200'], ['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A16.710'], ['C13.703.590'], ['G08.686.784.769'], ['E01.370.225.625.115.830', 'E05.200.625.115.830'], ['C14.907.355.830']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationship between pulmonary exacerbations and daily physical activity in adults with cystic fibrosis. | BACKGROUND: The aim of this study was to examine the relationship between pulmonary exacerbations and physical activity (PA) in adults with cystic fibrosis (CF).METHODS: We grouped adults with CF according to their exacerbation status in the year before study enrollment: (1) <1 exacerbation/year; (2) 1-2 exacerbations/... | ['Accelerometry', 'Adult', 'Cystic Fibrosis', 'Disease Progression', 'Energy Metabolism', 'Female', 'Forced Expiratory Volume', 'Humans', 'Male', 'Metabolic Equivalent', 'Middle Aged', 'Motor Activity', 'Pulmonary Diffusing Capacity', 'Sex Factors', 'Total Lung Capacity', 'Vital Capacity', 'Young Adult'] | 26,627,849 | [['E05.003'], ['M01.060.116'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['C23.550.291.656'], ['G03.295'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600.337', 'G03.680.365'], ['M01.060.116.630'], ['F01.145.632', 'G11.427.410.698'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does first line antiretroviral therapy increase the prevalence of cardiovascular risk factors in Indian patients?: A cross sectional study. | CONTEXT: Antiretroviral therapy (ART) is associated with a myriad of metabolic complications which are potential cardiovascular risk factors. Early detection of these risk factors could help in alleviating morbidity and mortality in human immunodeficiency virus (HIV) infected patients on ART.AIMS: To study the prevalen... | ['Adult', 'Anti-Retroviral Agents', 'Cardiovascular Diseases', 'Cross-Sectional Studies', 'Drug Therapy, Combination', 'Female', 'HIV Infections', 'Humans', 'Hypercholesterolemia', 'Hypertriglyceridemia', 'India', 'Lamivudine', 'Male', 'Middle Aged', 'Nevirapine', 'Prevalence', 'Risk Factors', 'Stavudine', 'Zidovudine'... | 24,346,381 | [['M01.060.116'], ['D27.505.954.122.388.077'], ['C14'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.319.310'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Betaine and folate status as cooperative determinants of plasma homocysteine in humans. | OBJECTIVE: Two published studies have demonstrated that betaine in the circulation is a determinant of plasma total homocysteine, but none had sufficient power to investigate the possible effect modification by folate status.METHODS AND RESULTS: We measured homocysteine, betaine, folate, vitamin B(6), and related compo... | ['Adult', 'Aged', 'Betaine', 'Choline', 'Creatinine', 'Dose-Response Relationship, Drug', 'Fasting', 'Female', 'Folic Acid', 'Homocysteine', 'Humans', 'Male', 'Methionine', 'Middle Aged', 'Sarcosine', 'Vitamin B 12', 'Vitamin B 6'] | 15,550,695 | [['M01.060.116'], ['M01.060.116.100'], ['D02.092.877.883.077', 'D02.675.276.125'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D03.383.129.308.207'], ['G07.690.773.875', 'G07.690.936.500'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D03.633.100.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The diagnostic utility of transthoracic echocardiography for the diagnosis of infective endocarditis in the real world of the Italian Registry on Infective Endocarditis. | BACKGROUND: The choice of the imaging modality (transthoracic [TTE] vs. transesophageal echocardiography [TEE]) for the diagnosis of infective endocarditis (IE) depends on different variables. Aim of the present study is to provide updated data on the diagnostic sensitivity and the clinical usefulness of TTE vs. TEE fr... | ['Echocardiography', 'Endocarditis', 'Evidence-Based Medicine', 'Female', 'Hospital Mortality', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Prevalence', 'Registries', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 23,489,364 | [['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.282'], ['H02.249.750', 'H02.403.200.400'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Neural regeneration in the noise-damaged chinchilla cochlea. | Recent studies in the bird ear have shown that degenerated hair cells are sometimes replaced by regenerated receptor cells. The present study evaluated the adult mammalian cochlea for evidence of hair-cell and nerve-fiber regeneration. Eighty-eight noise-damaged chinchilla cochleas were examined as plastic-embedded who... | ['Animals', 'Basement Membrane', 'Cell Nucleus', 'Chinchilla', 'Cochlea', 'Hair Cells, Auditory', 'Hearing Loss, Noise-Induced', 'Labyrinth Supporting Cells', 'Myelin Sheath', 'Nerve Degeneration', 'Nerve Fibers, Myelinated', 'Nerve Regeneration', 'Noise', 'Organ of Corti', 'Schwann Cells', 'Spiral Lamina'] | 1,602,919 | [['B01.050'], ['A10.272.220', 'A10.615.179'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.992.328'], ['A09.246.300.246'], ['A08.675.650.250', 'A08.675.650.915.750.600.350', 'A08.800.950.750.600.350', 'A09.246.300.246.577.325', 'A11.671.650.250', 'A11.671.650.915.750.600.350'], ['C09.21... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Validation of billing code combinations to identify cardiovascular magnetic resonance imaging scans in Ontario, Canada: a retrospective cohort study. | OBJECTIVES: Cardiovascular magnetic resonance (CMR) imaging is the gold-standard test for the assessment of heart function. Despite its importance, many jurisdictions lack specific billing codes that can be used to identify patient receipt of CMR in administrative databases, limiting the ability to perform 'big data' C... | ['Clinical Coding', 'Cohort Studies', 'Databases, Factual', 'Female', 'Heart', 'Humans', 'Information Storage and Retrieval', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Ontario', 'Predictive Value of Tests', 'Retrospective Studies', 'Sensitivity and Specificity', 'Universal Health Insurance'] | 30,297,345 | [['N04.452.758.708.200.400.500', 'N04.452.859.564.274', 'N05.715.360.300.715.500.249', 'N06.850.520.308.940.968.249'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.31... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Ultrasound diagnosis of filarial funiculoepididymitis. | Genital presentation of filarial disease is not uncommon in endemic areas of the world. Acute, febrile illness involving the epididymis and spermatic cord (funiculoepididymitis) is one of many such presentations. With an internationally mobile society, physicians today, even in nonendemic areas, may encounter patients ... | ['Adult', 'Animals', 'Epididymitis', 'Filariasis', 'Genital Diseases, Male', 'Humans', 'Male', 'Spermatic Cord', 'Ultrasonography', 'Wuchereria bancrofti'] | 8,886,076 | [['M01.060.116'], ['B01.050'], ['C12.294.199'], ['C01.610.335.508.700.750.361'], ['C12.294'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.444.777'], ['E01.370.350.850'], ['B01.050.500.500.294.400.937.463.708.150']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cavernous hemangioma of the kidney. | Three patients with cavernous hemangiomas of the kidney all presented with hematuria. In each there was found a poorly defined renal medullary mass with displacement of the calyces and renal vessels and paradoxical hypovascularity of the mass. This rare, benign tumor of the kidney should be considered in the presence o... | ['Adult', 'Child', 'Female', 'Hemangioma, Cavernous', 'Humans', 'Kidney', 'Kidney Neoplasms', 'Radiography'] | 1,202,983 | [['M01.060.116'], ['M01.060.406'], ['C04.557.645.375.385', 'C14.907.454.385', 'C15.378.463.515.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fiber bundle image restoration using deep learning. | We propose a deep learning-based restoration method to remove honeycomb patterns and improve resolution for fiber bundle (FB) images. By building and calibrating a dual-sensor imaging system, we capture FB images and corresponding ground truth data to train the network. Images without fiber bundle fixed patterns are re... | ['Deep Learning', 'Humans', 'Image Processing, Computer-Assisted', 'Optical Fibers', 'Signal-To-Noise Ratio'] | 30,821,775 | [['G17.035.250.500.250', 'G17.485.500', 'L01.224.050.375.530.250', 'L01.224.050.375.605.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E07.632.750'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Tourette's syndrome: [I-123]beta-CIT SPECT correlates of vocal tic severity. | OBJECTIVE: To examine in vivo the density of brain monoaminergic transporters in Tourette's syndrome (TS).BACKGROUND: TS is a heritable neuropsychiatric disorder characterized by chronic vocal and motor tics and is often associated with obsessive-compulsive symptoms. Hyperstimulation of dopamine receptors and dysfuncti... | ['Adult', 'Cocaine', 'Female', 'Humans', 'Iodine Radioisotopes', 'Male', 'Mesencephalon', 'Middle Aged', 'Tic Disorders', 'Tomography, Emission-Computed, Single-Photon', 'Tourette Syndrome'] | 9,781,531 | [['M01.060.116'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['A08.186.211.132.659'], ['M01.060.116.630'], ['C10.228.662.825', 'F03.625.992'], ['E01.370.350.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Exposure of cultured fibroblasts to the peptide PR-11 for the identification of induced proteome alterations and discovery of novel potential ligands. | The PR-11 peptide corresponds to the N-terminal and active region of the endogenously synthesized PR-39 molecule, of porcine origin. It is known to possess various biological effects including antimicrobial properties, angiogenic and anti-inflammatory activities. Apart from its reported activity as a proteasome inhibit... | ['Animals', 'Antimicrobial Cationic Peptides', 'Carrier Proteins', 'Cells, Cultured', 'Fibroblasts', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Immobilized Proteins', 'Ligands', 'Mass Spectrometry', 'Mitochondrial Proteins', 'NF-kappa B', 'Peptide Fragments', 'Proteasome Inhibitors', 'Proteome', 'Proteomics', 'Rats'... | 27,693,249 | [['B01.050'], ['D12.644.050', 'D12.776.543.695.054'], ['D12.776.157'], ['A11.251'], ['A11.329.228'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['D12.776.463'], ['D27.720.470.480'], ['E05.196.566'], ['D12.776.575'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['D12.644.541'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Interview for Deterioration in Daily Living Activities in Dementia: construct and concurrent validity in patients with mild to moderate dementia. | BACKGROUND: The purpose of the study was to translate the Interview for Deterioration in Daily Living Activities in Dementia (IDDD) into German and to evaluate the construct and concurrent validity in people with mild to moderate dementia.METHODS: IDDD data of two pooled samples (n = 301) were analyzed regarding ceilin... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Cross-Cultural Comparison', 'Disease Progression', 'Female', 'Germany', 'Humans', 'Interview, Psychological', 'Male', 'Mental Status Schedule', 'Netherlands', 'Occupational Therapy', 'Psychometrics', 'Reproducibility of Results', 'Statist... | 22,264,496 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['C23.550.291.656'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Different effects of adding white noise on cognitive performance of sub-, normal and super-attentive school children. | OBJECTIVES: Noise often has detrimental effects on performance. However, because of the phenomenon of stochastic resonance (SR), auditory white noise (WN) can alter the "signal to noise" ratio and improve performance. The Moderate Brain Arousal (MBA) model postulates different levels of internal "neural noise" in indiv... | ['Attention', 'Child', 'Cognition', 'Executive Function', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Mental Recall', 'Noise', 'Pattern Recognition, Physiological', 'Schools'] | 25,393,410 | [['F02.830.104.214'], ['M01.060.406'], ['F02.463.188'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463.425.540.641'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['F02.463.593.524'], ['I02.783', 'J03.832']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Discovery of significant rules for classifying cancer diagnosis data. | METHODS AND RESULTS: We introduce a new method to discover many diversified and significant rules from high dimensional profiling data. We also propose to aggregate the discriminating power of these rules for reliable predictions. The discovered rules are found to contain low-ranked features; these features are found t... | ['Algorithms', 'Biomarkers, Tumor', 'Diagnosis, Computer-Assisted', 'Gene Expression Profiling', 'Humans', 'Neoplasm Proteins', 'Neoplasms', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 14,534,178 | [['G17.035', 'L01.224.050'], ['D23.101.140'], ['E01.158', 'L01.313.500.750.100.158'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.624'], ['C04'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Morphometric evaluation of liver, spleen, and kidney wounds cleansing from necrosis after wound suturing by different methods: an experimental study. | Morphometrical evaluation of cleansing from necrosis was carried out 1-360 days after plastic repair of lacerated and contusion wounds of the liver, spleen, and kidney in rabbits by serous/muscular flaps from the greater curvature of the stomach on a vascular pedicle. This method of suturing led to 12-fold more rapid c... | ['Animals', 'Kidney', 'Lacerations', 'Liver', 'Necrosis', 'Rabbits', 'Spleen', 'Stomach', 'Surgical Flaps', 'Suture Techniques', 'Wound Healing'] | 19,526,114 | [['B01.050'], ['A05.810.453'], ['C26.540'], ['A03.620'], ['C23.550.717'], ['B01.050.150.900.649.313.968.700'], ['A10.549.700', 'A15.382.520.604.700'], ['A03.556.875.875'], ['A10.850.710', 'E07.862.710'], ['E04.987.775'], ['G16.762.891']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of Duodenal-Jejunal Exclusion and New Bilio-Pancreatic Diversion on Blood Glucose in Rats with Type 2 Diabetes Mellitus. | OBJECTIVE: The current study aimed to investigate the effects of duodenal-jejunal bypass (DJB), new bilio-pancreatic diversion (NBPD), and duodenal-jejunal exclusion (DJE) on blood glucose in rats with type 2 diabetes mellitus (T2DM).METHODS: Male Sprague Dawley rats were fed with high glucose, high fat food, and intra... | ['Animals', 'Biliopancreatic Diversion', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Diabetes Mellitus, Type 2', 'Duodenum', 'Gastric Bypass', 'Glucagon-Like Peptide 1', 'Glucose Tolerance Test', 'Insulin', 'Insulin Resistance', 'Jejunum', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Streptozocin'] | 28,233,263 | [['B01.050'], ['E04.210.120.086', 'E04.210.169'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.750.149', 'C19.246.300'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['D06.472.317.680.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Smoking habits among the hospital staff of a General Hospital in northern Greece: a long way for smoke-free hospitals. | BACKGROUND AND AIM: The aim of the study was to evaluate the smoking habits of all staff working in a General Hospital, and to examine whether these habits comply with the introduction of a tobacco law in July 2002, where smoking in enclosed public areas, including hospital buildings, has been forbidden in Greece.METHO... | ['Adult', 'Age Factors', 'Female', 'Greece', 'Humans', 'Male', 'Middle Aged', 'Nurses', 'Personnel, Hospital', 'Prevalence', 'Sex Factors', 'Smoking', 'Surveys and Questionnaires'] | 17,220,106 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.485.650', 'N02.360.650'], ['M01.526.485.740', 'N02.360.740'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension. | Phenotypic and contractile changes in pulmonary arterial smooth muscle cells (PASMCs) were examined in rats with pulmonary hypertension induced by hypoxia. Exposure to hypoxia induced pulmonary hypertension within 1-4 weeks. Staining with BrdU revealed that proliferative activities of PASMCs peaked at 1 week of hypoxic... | ['Actins', 'Amides', 'Animals', 'Cell Proliferation', 'Endothelin-1', 'Hypertension, Pulmonary', 'Hypoxia', 'Immunohistochemistry', 'Male', 'Muscle Contraction', 'Muscle, Smooth', 'Nicardipine', 'Phenotype', 'Pulmonary Artery', 'Pyridines', 'Rats', 'Rats, Sprague-Dawley', 'Thiazines', 'Time Factors'] | 19,498,269 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D02.065'], ['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['C08.381.423', 'C14.907.489.556'], ['C23.888.852.079'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effects of Prostate Water Pellets on the number of colonies, NO concentration and NOS activity in the prostate tissue of CBP rats]. | OBJECTIVE: To investigate the effects of Prostate Water Pellets (PWP) on the number of colonies, NO concentration and NOS activity in the prostate tissues of rats with chronic bacterial prostatitis (CBP).METHODS: A total of 120 healthy adult male Wistar rats weighing 250-300 g were equally randomized into 6 groups: bla... | ['Animals', 'Drugs, Chinese Herbal', 'Male', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Phytotherapy', 'Prostate', 'Prostatitis', 'Rats', 'Rats, Wistar'] | 20,626,170 | [['B01.050'], ['D20.215.784.500.350', 'D26.335'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D08.811.682.664.500.772'], ['E02.190.755'], ['A05.360.444.575', 'A10.336.707'], ['C12.294.565.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.90... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Circuit and plasticity defects in the developing somatosensory cortex of FMR1 knock-out mice. | Silencing of the Fmr1 gene causes fragile X syndrome. Although defects in synaptic plasticity in the cerebral cortex have been linked to cognitive impairments in Fmr1 knock-out (ko) mice, the specific cortical circuits affected in the syndrome are unknown. Here, we investigated the development of excitatory projections... | ['Animals', 'Disease Models, Animal', 'Excitatory Postsynaptic Potentials', 'Fragile X Mental Retardation Protein', 'Fragile X Syndrome', 'Gene Expression Regulation, Developmental', 'Genetic Predisposition to Disease', 'Growth Cones', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nervous System Malformation... | 18,480,274 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['D12.776.157.725.061', 'D12.776.631.299', 'D12.776.664.962.124'], ['C10.597.606.360.455.500', 'C16.131.260.830.300', 'C16.320.180.830.300', 'C16.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Costs and outcomes associated with IVF using recombinant FSH. | Cost and outcome estimates based on clinical trial data may not reflect usual clinical practice, yet they are often used to inform service provision and budget decisions. To expand understanding of assisted reproduction treatment in clinical practice, an economic evaluation of IVF/intracytoplasmic sperm injection (ICSI... | ['Adult', 'Costs and Cost Analysis', 'Dose-Response Relationship, Drug', 'Female', 'Fertility Agents, Female', 'Fertilization in Vitro', 'Follicle Stimulating Hormone', 'Guideline Adherence', 'Humans', 'Infertility, Female', 'Maternal Age', 'Pregnancy', 'Recombinant Proteins', 'Sperm Injections, Intracytoplasmic', 'Tre... | 19,778,478 | [['M01.060.116'], ['N03.219.151'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.696.875.552.344', 'D27.505.954.705.552.344'], ['E02.875.800.750', 'E05.820.800.750'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stress exposure and psychological stress responses are related to glucose concentrations during pregnancy. | OBJECTIVES: The role of stress in the development of gestational diabetes mellitus (GDM) has so far been neglected. We investigated the impact of stress exposure (pregnancy-related and pregnancy-unrelated major life events), psychological stress responses (perceived stress, subjective experience of stress, anxiety, dep... | ['Adult', 'Blood Glucose', 'Cross-Sectional Studies', 'Diabetes, Gestational', 'Female', 'Glucose Tolerance Test', 'Glycopeptides', 'Humans', 'Hydrocortisone', 'Pregnancy', 'Risk Factors', 'Stress, Psychological', 'Switzerland'] | 27,169,679 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['D09.400.420', 'D12.644.233'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Bortezomib Targets Sp Transcription Factors in Cancer Cells. | Bortezomib alone and in combination with other anticancer agents are extensively used for chemotherapeutic treatment of multiple myeloma (MM) patients and are being developed for treating other cancers. Bortezomib acts through multiple pathways, and in this study with ANBL-6 and RPMI 8226 MM cells we show that bortezom... | ['Apoptosis', 'Bortezomib', 'Caspase 8', 'Cell Line, Tumor', 'Cell Proliferation', 'Down-Regulation', 'Fas-Associated Death Domain Protein', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Multiple Myeloma', 'Neoplasms', 'Sp Transcription Factors'] | 30,115,673 | [['G04.146.954.035'], ['D01.029.260.110.500', 'D01.132.285.500', 'D02.203.200.500', 'D03.383.679.450'], ['D08.811.277.656.262.500.126.550.800', 'D08.811.277.656.300.200.126.550.800', 'D12.644.360.024.285.037', 'D12.644.360.075.405.550.800', 'D12.644.360.075.421.037', 'D12.776.157.057.018.037', 'D12.776.476.024.320.025'... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rearrangement of the human CDC5L gene by a t(6;19)(p21;q13.1) in a patient with multicystic renal dysplasia. | Genetic studies have implicated the short arm of chromosome 6 in congenital hydronephrosis. In previous studies, we described a fetus carrying a t(6;19)(p21;q13.1) as the sole cytogenetic anomaly and suffering from bilateral multicystic renal dysplasia caused by a bilateral complete pelviureteric junction obstruction, ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'CHO Cells', 'COS Cells', 'Cell Cycle Proteins', 'Chromosomes, Human, Pair 19', 'Chromosomes, Human, Pair 6', 'Cricetinae', 'Exons', 'Fetal Diseases', 'Gene Expression Regulation, Developmental', 'Humans', 'Hydronephrosis', 'In Situ Hybridization, Fluorescence', 'Intr... | 9,598,309 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.200', 'A11.436.155'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D12.776.167'], ['A11.284.187.520.300.460.465', 'G05.360.162.520.300.460.465'], ['A11.284.187.520.300.325.330', 'G05.360.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Quantitative analysis of hemoglobin content in polymeric nanoparticles as blood substitutes using Fourier transform infrared spectroscopy. | Based on the penetrability of IR within the polymeric nanoparticles, a novel Fourier transform infrared spectroscopy (FTIR) method, with polyacrylonitrile (PAN) as the internal reference standard, was developed to quantify the hemoglobin (Hb) content in Hb-based polymeric nanoparticles (HbPN). The HbPN was fabricated b... | ['Animals', 'Blood Substitutes', 'Calibration', 'Cattle', 'Efficiency', 'Hemoglobins', 'Microscopy, Electron, Transmission', 'Nanoparticles', 'Particle Size', 'Polyesters', 'Polyethylene Glycols', 'Polymers', 'Reference Standards', 'Spectroscopy, Fourier Transform Infrared'] | 19,730,991 | [['B01.050'], ['D27.505.954.502.140', 'J01.637.087.249'], ['E05.978.155'], ['B01.050.150.900.649.313.500.380.271'], ['F02.784.692.351', 'N04.452.209'], ['D12.776.124.400', 'D12.776.422.316.762'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['J01.637.512.600'], ['G02.712'], ['D05.750.728', 'D25.720.728', 'J01.637.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Tunable directive radiation of surface-plasmon diffraction gratings. | We experimentally demonstrate tunable radiation from a periodic array of plasmonic nanoscatterers, tailored to convert surface plasmon polaritons into directive leaky modes. Extending our previous studies on efficient directional beaming based on leaky-wave radiation from periodic gratings driven by a subwavelength sli... | ['Equipment Design', 'Equipment Failure Analysis', 'Light', 'Refractometry', 'Scattering, Radiation', 'Surface Plasmon Resonance'] | 23,481,732 | [['E05.320'], ['E05.325.192'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.196.808', 'H01.671.617.755'], ['E05.196.822', 'G01.867'], ['E05.196.890', 'E05.601.043.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative in vitro activity of piperacillin, piperacillin-sulbactam and piperacillin-tazobactam against nosocomial pathogens isolated from intensive care patients. | We investigated the antimicrobial activity of piperacillin-tazobactam versus piperacillin-sulbactam against common nosocomial pathogens (n = 565) isolated from intensive care patients. For Gram-positive bacteria, antimicrobial susceptibilities to the two piperacillin-beta-lactamase inhibitor combinations were almost id... | ['Anti-Bacterial Agents', 'Cross Infection', 'Drug Therapy, Combination', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Humans', 'Microbial Sensitivity Tests', 'Penicillanic Acid', 'Piperacillin', 'Piperacillin, Tazobactam Drug Combination', 'Sulbactam'] | 14,616,732 | [['D27.505.954.122.085'], ['C01.248', 'C23.550.291.875.500'], ['E02.319.310'], ['B03.440'], ['B03.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D02.065.589.099.750.687', 'D02.886.108.750.687', 'D03.633.100.300.750.687'], ['D02.065.589.099.750.75... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neural responses to Mooney images reveal a modular representation of faces in human visual cortex. | The way in which information about objects is represented in visual cortex remains controversial. One model of human object recognition poses that information is processed in modules, highly specialised for different categories of objects; an opposing model appeals to a distributed representation across a large network... | ['Adult', 'Awareness', 'Brain Mapping', 'Discrimination Learning', 'Face', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Parahippocampal Gyrus', 'Pattern Recognition, Visual', 'Problem Solving', 'Psychomotor Performance', 'Temporal Lobe', 'Visual Cortex', 'Visual Path... | 14,741,646 | [['M01.060.116'], ['F02.463.188.150'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.425.280'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['A08.186.211.180.590.750', 'A08.186.211.180.710', 'A08.186.211.200.885.287.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Sugars Require Rigid Multivalent Displays for Activation of Mouse Sperm Acrosomal Exocytosis. | As a prerequisite to mammalian fertilization, the sperm acrosomal vesicle fuses with the plasma membrane and the acrosome contents are exocytosed. Induction occurs through engagement of the sperm receptors by multiple sugar residues. Multivalent polymers displaying mannose, fucose, or GlcNAc are effective synthetic ind... | ['Acrosome', 'Animals', 'Carbohydrates', 'Carbon-13 Magnetic Resonance Spectroscopy', 'Exocytosis', 'Male', 'Mice', 'Proton Magnetic Resonance Spectroscopy'] | 28,509,550 | [['A05.360.490.890.820.100', 'A11.284.430.214.190.875.190.550.040', 'A11.497.760.400.100'], ['B01.050'], ['D09'], ['E05.196.867.519.136'], ['G04.468'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.196.867.519.775']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overloading the immunity of the mosquito Anopheles gambiae with multiple immune challenges. | BACKGROUND: Melanisation - the production and deposition of a layer of melanin that encapsulates many pathogens, including bacteria, filarial nematodes and malaria parasites is one of the main immune responses in mosquitoes. Can a high parasite load overload this immune response? If so, how is the melanisation response... | ['Animals', 'Anopheles', 'Color', 'Insect Vectors', 'Melanins'] | 27,080,035 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['G01.590.540.199'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['D12.125.072.050.875.379', 'D23.767.620']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapid Generation of Primary Murine Melanocyte and Fibroblast Cultures. | Defects in fibroblast or melanocyte function are associated with skin diseases, including poor barrier function, defective wound healing, pigmentation defects and cancer. Vital to the understanding and amelioration of these diseases are experiments in primary fibroblast and melanocyte cultures. Nevertheless, current pr... | ['Animals', 'Cell Culture Techniques', 'Cells, Cultured', 'Female', 'Fibroblasts', 'Humans', 'Male', 'Melanocytes', 'Mice, Inbred C57BL', 'Time Factors'] | 31,305,511 | [['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.750', 'A11.436.613'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['G01.910.857']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prelabour rupture of the membranes at term--no advantage of delaying induction for 24 hours. | We performed a prospective randomized study to compare maternal and fetal outcomes in pregnancies with prelabour rupture of the membranes (PROM) at term with early induction of labour or expectant management, 126 women with singleton pregnancy, cephalic presentation and gestational duration > or = 37 weeks, were random... | ['Adult', 'Cesarean Section', 'Female', 'Fetal Membranes, Premature Rupture', 'Humans', 'Labor, Induced', 'Oxytocics', 'Oxytocin', 'Pregnancy', 'Prospective Studies', 'Time Factors'] | 10,554,936 | [['M01.060.116'], ['E04.520.252.500'], ['C13.703.420.339'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.520.252.968'], ['D27.505.696.875.737', 'D27.505.954.705.737'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['G08.686.784.769'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Proteinases, their inhibitors, and cytokine profiles in acute wound fluid. | Wound healing is a complex process involving the interactions of many different cell types, matrix components and biological factors, including proteinases and cytokines. This study compared the levels of proteinases (matrix metalloproteinases and plasminogen activators), proteinase inhibitors (tissue inhibitors of met... | ['Acute Disease', 'Breast Neoplasms', 'Colorectal Neoplasms', 'Cytokines', 'Enzyme-Linked Immunosorbent Assay', 'Exudates and Transudates', 'Growth Substances', 'Humans', 'Inflammation', 'Interleukin-1', 'Interleukin-6', 'Matrix Metalloproteinase 1', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 3', 'Matrix M... | 11,115,151 | [['C23.550.291.125'], ['C04.588.180', 'C17.800.090.500'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dental Injuries in a Sample of Portuguese Militaries - A Preliminary Research. | Introduction: Traumatic dental and maxillofacial injuries are very common and appear to affect approximately 20-30% of permanent dentition, with often serious psychological, economic, functional, and esthetic consequences. Militaries are a highest risk group for orofacial trauma, not only because they are constantly en... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Facial Injuries', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Military Personnel', 'Pilot Projects', 'Portugal', 'Prevalence', 'Surveys and Questionnaires'] | 29,796,597 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C10.900.300.284', 'C26.915.300.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Different hCG assays to measure ectopic hCG secretion in bladder carcinoma patients. | We evaluated the clinical performance of assays measuring intact human chorionic gonadotropin alone (i-hCG), intact and nicked human chorionic gonadotropin (i-hCG and hCGn), free beta-subunit (free beta-hCG) and total beta-human chorionic gonadotropin (t-hCG) using different commercial kits, in a group of bladder carci... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Chorionic Gonadotropin', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Proteins', 'Reagent Kits, Diagnostic', 'Sensitivity and Specificity', 'Urinary Bladder Neoplasms'] | 8,855,978 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.624'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['E05.318.370.800', 'E05.318.740... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Calcium transients evoked by electrical stimulation of smooth muscle from guinea-pig ileum recorded by the use of Fura-2. | 1. Intracellular free calcium levels were recorded in strips of longitudinal smooth muscle from guinea-pig ileum, by the use of the fluorescent calcium indicator Fura-2. 2. The resting intracellular free calcium concentration was estimated to be 210 nM. Many muscle strips showed spontaneous bursts of contractions, acco... | ['Action Potentials', 'Animals', 'Atropine', 'Benzofurans', 'Calcium', 'Fura-2', 'Guinea Pigs', 'Ileum', 'In Vitro Techniques', 'Muscle Contraction', 'Muscle, Smooth', 'Tetrodotoxin', 'Time Factors', 'Verapamil'] | 3,256,613 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['D03.633.100.127'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.383.129.462.285', 'D03.633.100.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dengue: etiology of acute febrile illness in Abidjan, C?te d'Ivoire, in 2011-2012. | BACKGROUND: The burden of dengue in Africa is not well understood. A prospective study was conducted in Abidjan, C?te d'Ivoire from December 2011 to December 2012 to estimate the proportion of dengue and malaria cases among febrile patients during a period when dengue was not known to be circulating in the region, and ... | ['Aedes', 'Animals', 'Antibodies, Viral', "Cote d'Ivoire", 'Dengue', 'Dengue Virus', 'Enzyme-Linked Immunosorbent Assay', 'Epidemiological Monitoring', 'Female', 'Fever', 'Humans', 'Malaria', 'Male', 'Prevalence', 'Prospective Studies', 'Real-Time Polymerase Chain Reaction'] | 26,385,938 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['Z01.058.290.190.272'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['B04.820.578.344.350.270'], ['E05.478.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Acute hyperparathyroidism. Clinical, laboratory and ultrastructural findings in a variant of primary hyperparathyroidism. | In a series of 6 patients out of 47 cases with extrarenal hyperparathyroidism we investigated the clinical, laboratory and ultrastructural peculiarities of acute hyperparathyroidism. It was found that there are characteristic differences between both entities which, however, are fluid. Clinically more severe were neuro... | ['Acute Disease', 'Adenoma', 'Adult', 'Aged', 'Female', 'Humans', 'Hypercalcemia', 'Hyperparathyroidism', 'Male', 'Middle Aged', 'Parathyroid Glands', 'Parathyroid Hormone'] | 7,392,528 | [['C23.550.291.125'], ['C04.557.470.035'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.174.451', 'C18.452.950.340'], ['C19.642.355'], ['M01.060.116.630'], ['A06.300.560'], ['D06.472.699.590', 'D12.644.548.587']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
teashirt is required for head-versus-tail regeneration polarity in planarians. | Regeneration requires that the identities of new cells are properly specified to replace missing tissues. The Wnt signaling pathway serves a central role in specifying posterior cell fates during planarian regeneration. We identified a gene encoding a homolog of the Teashirt family of zinc-finger proteins in the planar... | ['Animals', 'Gene Expression Regulation, Developmental', 'Head', 'Homeodomain Proteins', 'In Situ Hybridization', 'Planarians', 'Principal Component Analysis', 'RNA Interference', 'Regeneration', 'Reverse Transcriptase Polymerase Chain Reaction', 'Tail', 'Wnt Signaling Pathway', 'Zinc Fingers'] | 25,725,068 | [['B01.050'], ['G05.308.310'], ['A01.456'], ['D12.776.260.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['B01.050.500.500.736.847.610'], ['E05.318.740.562'], ['G05.308.203.374.790'], ['G16.762'], ['E05.393.620.500.725'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary practices among overweight and obese Chinese children in Kota Bharu, Kelantan. | UNLABELLED: INTRDUCTION: Obesity and chronic diseases have been increasing since the last few decades alongside rapid economic development in developed and developing countries. The alarming increase in the prevalence of childhood obesity had been shown by many epidemiological studies worldwide. The aims of this study ... | ['Child', 'Child Health Services', 'China', 'Cross-Sectional Studies', 'Feeding Behavior', 'Female', 'Health Behavior', 'Humans', 'Malaysia', 'Male', 'Obesity', 'Schools'] | 22,135,868 | [['M01.060.406'], ['N02.421.143.130'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.487'], ['C18.654.726.500', 'C23.888.144.699.50... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Isolation of Escherichia coli RNA polymerase binding sites on T5 and T7 DNA: further evidence for sigma-dependent recognition of A-T-rich DNA sequences. | Previous isolation and analysis of E. coli RNA polymerase (EC 2.7.7.6) binding sites on lambda DNA had demonstrated the existence of a sigma-dependent process of recognition of A-T-rich DNA sequences. We have now extended this finding to T5 and T7 DNA and h?ve provided evidence for the double-strandedness of the isolat... | ['Adenine Nucleotides', 'Base Sequence', 'Binding Sites', 'Coliphages', 'Cytosine Nucleotides', 'DNA, Viral', 'DNA-Directed RNA Polymerases', 'Deoxyribonucleases', 'Electrophoresis, Polyacrylamide Gel', 'Endonucleases', 'Escherichia coli', 'Guanine Nucleotides', 'Hydrolysis', 'Nucleic Acid Conformation', 'Nucleic Acid ... | 4,355,373 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['B04.123.205'], ['D03.383.742.686.246', 'D13.695.740.246', 'D13.695.827.232'], ['D13.444.308.568'], ['D08.811.913.696.445.735.270'], ['D08.811.277.352.335'], ['E05.196.401... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevalence of low back pain among rice farmers in a rural community in Thailand. | OBJECTIVE: To determine the prevalence of low back pain (LBP) among rice farmers in a rural community in Phitsanulok, Thailand.MATERIAL AND METHOD: A cross-sectional survey was conducted among 283 rice farmers in Wangnamkhu subdistrict, Muang district, Phitsanulok province, a rural community in Lower Northern Thailand.... | ['Activities of Daily Living', 'Adult', 'Aged', "Agricultural Workers' Diseases", 'Agriculture', 'Cross-Sectional Studies', 'Female', 'Health Surveys', 'Humans', 'Low Back Pain', 'Male', 'Middle Aged', 'Prevalence', 'Risk Factors', 'Rural Population', 'Sex Distribution', 'Surveys and Questionnaires', 'Thailand'] | 21,675,453 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['C24.080'], ['J01.040'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Absence of common ALL antigen on normal bipotent myeloid, erythroid, and granulocyte progenitors. | The presence of the common acute lymphoblastic leukemia antigen (CALLA) on leukemic cells from the great majority of patients with non-T cell acute lymphoblastic leukemia and chronic myelogenous leukemia in blast crisis suggests that CALLA could be differentiation antigen expressed by normal lymphoid and myeloid stem c... | ['Acute Disease', 'Antigens, Neoplasm', 'Blood Coagulation', 'Bone Marrow Cells', 'Cell Differentiation', 'Cells, Cultured', 'Colony-Forming Units Assay', 'Cytotoxicity, Immunologic', 'Erythrocytes', 'Granulocytes', 'Hematopoiesis', 'Humans', 'Leukemia, Lymphoid', 'Methylcellulose'] | 6,941,821 | [['C23.550.291.125'], ['D23.050.285'], ['G09.188.390.150'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['G12.287'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.3... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical problem solving: Mental confusion and hypoxaemia after scuba diving. | INTRODUCTION: We report a case of a diving accident associating both cerebral symptoms and signs of respiratory impairment after two dives. The objective is to describe the process for obtaining the diagnosis.CASE REPORT: A 52-year-old man experienced mental confusion associated with hypoxaemia after surfacing. All dec... | ['Confusion', 'Decompression Sickness', 'Diving', 'Humans', 'Hypoxia', 'Male', 'Middle Aged'] | 32,557,423 | [['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['C26.120.248'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['M01.060.116.630']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Surgical treatment of patients with cancer of the big papilla of the duodenum]. | Results of treatment in 114 patients with duodenal big papilla (DBP) tumor were adduced. Radical operations were performed in 63 patients, including in 27--pancreatoduodenal resection, in 36--local resection of DBP. Postoperative complications were occurred in 14% of patients. Postoperative lethality was 0.9%. Indexes ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Digestive System Surgical Procedures', 'Duodenal Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Ultrasonography'] | 15,071,990 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210'], ['C04.588.274.476.411.445', 'C06.301.371.411.445', 'C06.405.249.411.445', 'C06.405.469.275.270', 'C06.405.469.491.445'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E01.370.350.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of an unusual variant peroxisome biogenesis disorder caused by mutations in the PEX16 gene. | BACKGROUND: Zellweger syndrome spectrum disorders are caused by mutations in any of at least 12 different PEX genes. This includes PEX16, which encodes an integral peroxisomal membrane protein involved in peroxisomal membrane assembly. PEX16-defective patients have been reported to have a severe clinical presentation. ... | ['Adolescent', 'Catalase', 'Child', 'Child, Preschool', 'DNA Mutational Analysis', 'Erythrocytes', 'Female', 'Fibroblasts', 'Fluorescent Antibody Technique', 'Genetic Complementation Test', 'Humans', 'Infant', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Membrane Proteins', 'Mutation', 'Peroxisomes'] | 20,647,552 | [['M01.060.057'], ['D08.811.682.732.332'], ['M01.060.406'], ['M01.060.406.448'], ['E05.393.760.700.300'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.329.228'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E05.393... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The problems of generations: and generational analysis. | The focus of this paper is two fold: 1. conceptual and methodological problems underlying the life-span sociology literature that heretofore have not been discussed; and 2. application of the generational analysis model to the question of life cycle change in personal values. Specifically, we address the issues of whet... | ['Age Factors', 'Aging', 'Civil Rights', 'Epidemiologic Methods', 'Ethics', 'Humans', 'Morals', 'Religion', 'Social Values', 'Sociometric Techniques'] | 391,723 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An overview of multidisciplinary research resources at the Osaka University Center for Twin Research. | Osaka University Center for Twin Research is currently organizing a government-funded, multidisciplinary research project using a large registry of aged twins living in Japan. The purpose of the project is to collect various information as well as biological resources from registered twins, and to establish a biobank a... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomedical Research', 'Cognition', 'Cohort Studies', 'Diseases in Twins', 'Female', 'Health Resources', 'Humans', 'Japan', 'Life Style', 'Male', 'Middle Aged', 'Quality of Life', 'Registries', 'Twins', 'Universities'] | 23,298,684 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['H01.770.644.145'], ['F02.463.188'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.291.750'], ['N03.349.340', 'N05.300.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], [... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Tec... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Barriers to accessing cervical cancer screening among HIV positive women in Kgatleng district, Botswana: A qualitative study. | BACKGROUND: Low and middle-income countries have a greater share of the cervical cancer burden, but lower screening coverage, compared to high-income countries. Moreover, screening uptake and disease outcomes are generally worse in rural areas as well as in the HIV positive population. Efforts directed at increasing th... | ['Adult', 'Botswana', 'Early Detection of Cancer', 'Female', 'HIV Infections', 'Health Services Accessibility', 'Humans', 'Middle Aged', 'Patient-Centered Care', 'Qualitative Research', 'Rural Health', 'Rural Population', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Uterine Cervical Neoplasms'] | 30,356,248 | [['M01.060.116'], ['Z01.058.290.175.230'], ['E01.390.500'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.590.233.727.407'], ['H01... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[The prognosis of insulin-dependent diabetes mellitus]. | The prognosis of juvenile-dependent diabetics is characterized by an overmortality of 600 per cent. The quality of life is reduced, too, since about 15 per cent of the patients with a diabetes onset before the age of 31 will become blind, 10-15 per cent will become amputated on calf or thigh and 20-30 per cent will dev... | ['Adolescent', 'Adult', 'Aged', 'Diabetes Mellitus', 'Female', 'Germany, East', 'Humans', 'Insulin', 'Male', 'Middle Aged', 'Prognosis'] | 7,013,293 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750', 'C19.246'], ['Z01.586.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['M01.060.116.630'], ['E01.789']] | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The psychosocial work environment and alcohol dependence: a prospective study. | AIMS: To examine whether a stressful psychosocial work environment predicts alcohol dependence.METHODS: Alcohol dependence of participants in the Whitehall II occupational cohort of London based civil servants (1985-88) was measured in 1991-93 using the CAGE questionnaire. The psychosocial work environment was measured... | ['Adult', 'Alcoholism', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Odds Ratio', 'Prospective Studies', 'Risk Factors', 'Stress, Psychological', 'Workplace'] | 14,985,516 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.830.600.600'], ['E05.318.372.500.7... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Combined Vitamin B-12 and Balanced Protein-Energy Supplementation Affect Homocysteine Remethylation in the Methionine Cycle in Pregnant South Indian Women of Low Vitamin B-12 Status. | Background: Low-quality dietary protein intake and vitamin B-12 deficiency could interact to decrease methionine transmethylation and remethylation rates during pregnancy and may affect epigenetic modifications of the fetal genome.Objective: The objective of this randomized, partially open-labeled intervention trial wa... | ['Adult', 'Amino Acids', 'Animals', 'Dietary Proteins', 'Energy Intake', 'Female', 'Food, Fortified', 'Homocysteine', 'Humans', 'India', 'Long Interspersed Nucleotide Elements', 'Maternal Nutritional Physiological Phenomena', 'Methionine', 'Methylation', 'Placenta', 'Pregnancy', 'Pregnancy Complications', 'Promoter Reg... | 28,446,631 | [['M01.060.116'], ['D12.125'], ['B01.050'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.240.340'], ['G07.203.300.515', 'J02.500.515'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['G02.111.570.080.708.330.800.400', 'G05.360.080.708.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 |
Structural changes in the L photointermediate of bacteriorhodopsin. | The L to M reaction of the bacteriorhodopsin photocycle includes the crucial proton transfer from the retinal Schiff base to Asp85. In spite of the importance of the L state in deciding central issues of the transport mechanism in this pump, the serious disagreements among the three published crystallographic structure... | ['Amino Acid Sequence', 'Bacteriorhodopsins', 'Biological Transport', 'Crystallography, X-Ray', 'Darkness', 'Light', 'Lysine', 'Models, Molecular', 'Molecular Sequence Data', 'Protein Conformation', 'Protons', 'Reproducibility of Results', 'Retinaldehyde', 'Water'] | 17,141,271 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.090.200', 'D12.776.157.530.450.250.875.249', 'D12.776.543.585.450.250.875.249', 'D12.776.752.812.249'], ['G03.143'], ['E05.196.309.742.225'], ['G01.590.540.233'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D12.125.068.555', 'D12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Toxicokinetics and toxicity of zinc under time-varying exposure in the guppy (Poecilia reticulata). | Levels of toxic substances released into the environment are often highly variable and fluctuate over time. The present study deals with a simple type of time-variable exposure, diluted pulse. We determined toxicokinetic parameters of zinc in guppy fish (Poecilia reticulata) and evaluated the applicability of a toxicok... | ['Animals', 'Environmental Exposure', 'Fresh Water', 'Half-Life', 'Indonesia', 'Kinetics', 'Models, Biological', 'Poecilia', 'Time Factors', 'Water Pollutants, Chemical', 'Zinc'] | 11,345,451 | [['B01.050'], ['N06.850.460.350'], ['G16.500.275.280', 'N06.230.232'], ['G01.910.405'], ['Z01.252.145.380', 'Z01.639.580'], ['G01.374.661', 'G02.111.490'], ['E05.599.395'], ['B01.050.150.900.493.850.280.680'], ['G01.910.857'], ['D27.888.284.903.655'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
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