Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The role of U2AF35 and U2AF65 in enhancer-dependent splicing. | Splicing enhancers are RNA sequence elements that promote the splicing of nearby introns. The mechanism by which these elements act is still unclear. Some experiments support a model in which serine-arginine (SR)-rich proteins function as splicing activators by binding to enhancers and recruiting the splicing factor U2... | ['Base Sequence', 'Enhancer Elements, Genetic', 'Immunoglobulin M', 'Mutation', 'Nuclear Proteins', 'Pyrimidines', 'RNA Precursors', 'RNA Splicing', 'RNA, Messenger', 'Ribonucleoproteins', 'Splicing Factor U2AF'] | 11,421,359 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.377.715.548.114.619.574'], ['G05.365.590'], ['D12.776.660'], ['D03.383.742'], ['D13.400.730',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Extraneural perineurioma of the face: an unusual cutaneous presentation of an uncommon tumour. | Perineurioma is an uncommon, benign tumour of the peripheral nerve sheath that has two major clinicopathological forms -- intraneural and extraneural. We present a case of extraneural perineurioma that occurred at an unusual site -- the facial skin of a 70-year-old woman -- which illustrates the wide, and potentially m... | ['Aged', 'Facial Neoplasms', 'Female', 'Humans', 'Nerve Sheath Neoplasms', 'Skin Neoplasms'] | 11,437,432 | [['M01.060.116.100'], ['C04.588.443.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.580.600', 'C10.551.775.500', 'C10.668.829.725.500'], ['C04.588.805', 'C17.800.882']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of melatonin to treat sleep disorder in adults with intellectual disabilities in community settings - the evaluation of three cases using actigraphy. | BACKGROUND: Sleep disorders are known to be very prevalent in adults with intellectual disabilities (ID) but to date there has been limited objective assessment of either sleep disorders or of interventions such as the use of melatonin.METHODOLOGY: A protocol-driven assessment and intervention procedure was followed wi... | ['Adult', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Follow-Up Studies', 'Humans', 'Intellectual Disability', 'Melatonin', 'Middle Aged', 'Polysomnography', 'Sleep Disorders, Circadian Rhythm', 'Sleep Initiation and Maintenance Disorders', 'Treatment Outcome'] | 18,444,986 | [['M01.060.116'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['D03.633.100.473.914.481', 'D0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tracking calcification in tissue-engineered bone using synchrotron micro-FTIR and SEM. | One novel tissue engineering approach to mimic in vivo bone formation is the use of aggregate or micromass cultures. Various qualitative and quantitative techniques, such as histochemical staining, protein assay kits and RT-PCR, have been used previously on cellular aggregate studies to investigate how these intricate ... | ['Animals', 'Bone and Bones', 'Calcification, Physiologic', 'Cell Line', 'Mice', 'Microscopy, Electron, Scanning', 'Osteoblasts', 'Spectrometry, X-Ray Emission', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties', 'Synchrotrons', 'Tissue Engineering'] | 25,450,052 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A11.329.629'], ['E05.196.867.800', 'E05.799.830'], ['E05.196.712.726.676.70... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Reduced lower extremity vibratory perception in osteoarthritis of the knee. | OBJECTIVE: Vibratory perception threshold (VPT) assesses a distinct yet related sensory pathway that has been associated with neuropathic arthropathy but has not been assessed in knee osteoarthritis (OA). The purpose of this study was to evaluate VPT in subjects with knee OA to determine whether the lower extremity aff... | ['Cross-Sectional Studies', 'Female', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Sensory Thresholds', 'Touch', 'Vibration'] | 18,163,397 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['F02.463.593.710'], ['F02.830.816.850', 'G11.561.790.850'], ['G01.374.930']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Microcomputer reconstruction for analysis of spinal deformity and lung volume in hypokyphotic scoliosis. | Current techniques for imaging chest deformity are limited to two-dimensional representations, and clinical testing for lung volume measurements are based on pulmonary function studies that are effort-dependent. The authors evaluated spine deformity and lung volume by using a new three-dimensional microcomputer imaging... | ['Adolescent', 'Computer Graphics', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Lung', 'Male', 'Microcomputers', 'Scoliosis', 'Tomography, X-Ray Computed'] | 2,259,972 | [['M01.060.057'], ['L01.224.108', 'L01.296.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A04.411'], ['L01.224.230.260.550'], ['C05.116.900.800.875'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Potentiation of cisplatin sensitivity of cisplatin-resistant human ovarian cancer cell lines by L-buthionine-S,R-sulfoximine]. | We established two human ovarian cancer cell lines (KK and MH) from the ascites of patients who did not respond to cisplatin (CDDP)-based combination chemotherapy. These cell lines showed higher resistance to CDDP in vitro than HRA cells which were established previously in our laboratory, and also have cross resistanc... | ['Adenocarcinoma', 'Adult', 'Buthionine Sulfoximine', 'Cisplatin', 'Drug Resistance', 'Drug Synergism', 'Female', 'Glutathione', 'Humans', 'Methionine Sulfoximine', 'Middle Aged', 'Ovarian Neoplasms', 'Tumor Cells, Cultured'] | 8,040,625 | [['C04.557.470.200.025'], ['M01.060.116'], ['D02.886.030.676.620.125', 'D12.125.166.676.620.125'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G07.690.773.984'], ['G07.690.773.968.477'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.030.676.620', 'D12.125.166.676.620'], ['M01.060.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Duchenne-like muscular dystrophy in two sisters with normal karyotypes: evidence for autosomal recessive inheritance. | Two sisters, products of a consanguineous marriage (with a total of 12 children) showed muscle weakness at ages 7 and 6 yrs, respectively. The symptoms progressed rapidly and the patients were confined to wheelchairs at ages of 12 and 11 yrs, respectively. They had mild facial weakness and pseudohypertrophy of the calv... | ['Creatine Kinase', 'Female', 'Genes, Recessive', 'Humans', 'Karyotyping', 'Muscular Dystrophies', 'Pedigree'] | 4,042,397 | [['D08.811.913.696.640.150'], ['G05.360.340.024.340.415', 'G05.420.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['C05.651.534.500', 'C10.668.491.175.500', 'C16.320.577'], ['E05.393.673']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical effectiveness of the method of extracorporeal heparin precipitation of plasma proteins (selective plasmapheresis) in patients with immune complex pathology]. | The authors analyse the efficacy of extracorporeal heparin precipitation of plasma proteins (selective plasmapheresis) in patients with immune complex pathology. The method lies in extracorporeal precipitation at +4 degrees C of fibronectin, cryofibrinogen and other macromolecular complexes with the aid of heparin, fol... | ['Adolescent', 'Adult', 'Chemical Precipitation', 'Collagen Diseases', 'Female', 'Fibronectins', 'Follow-Up Studies', 'Freezing', 'Heparin', 'Humans', 'Immune Complex Diseases', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Plasmapheresis', 'Purpura, Schoenlein-Henoch'] | 2,931,845 | [['M01.060.057'], ['M01.060.116'], ['E05.196.150', 'G02.159'], ['C17.300.200'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro immune responses to hepatitis B surface antigen (Pre-S2 and S) following remote infection by hepatitis B virus in humans. | In this report we evaluate the human immune response to hepatitis B surface antigen (HBsAg) following remote infection with hepatitis B virus (HBV). HBsAg-reactive lymphocytes can be readily demonstrated in the peripheral blood of individuals with established immunity following infection with HBV. In vitro stimulation ... | ['Adult', 'Antibody Specificity', 'Cells, Cultured', 'Enzyme-Linked Immunosorbent Assay', 'Hepatitis B', 'Hepatitis B Surface Antigens', 'Hepatitis B virus', 'Humans', 'In Vitro Techniques', 'Indomethacin', 'Leukocytes, Mononuclear', 'Recombinant Proteins', 'Rosette Formation'] | 2,768,432 | [['M01.060.116'], ['G12.100'], ['A11.251'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D23.050.327.495.500.475'], ['B04.280.375.650.425', 'B04.450.390.650.425... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Biodegradable osteosynthesis applied to craniofacial surgery]. | Since skin problems as decubitus and infections are well known risks in osteoplastic trepanations in congenital malformations in children, we searched for a reduction in size of the implants and the possibility to use biodegradable materials. After design of special constructions regarding dimension and stability purpo... | ['Acrocephalosyndactylia', 'Animals', 'Biodegradation, Environmental', 'Bone Screws', 'Child', 'Craniofacial Dysostosis', 'Humans', 'Skull', 'Swine'] | 2,083,460 | [['C05.116.099.370.894.232.015', 'C05.116.099.370.894.819.100', 'C05.660.207.240.100', 'C05.660.585.800.100', 'C05.660.906.364.100', 'C05.660.906.819.100', 'C16.131.621.207.240.100', 'C16.131.621.585.800.100', 'C16.131.621.906.364.100', 'C16.131.621.906.819.100'], ['B01.050'], ['N06.230.080.600.500', 'N06.850.460.375.5... | ['Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Midlife Predictors of Health-Related Quality of Life in Older Women. | Background: Midlife represents an important time to evaluate health status and health behaviors that may affect health-related quality of life (HRQL) in later years. This study examines change in women's HRQL over 11 years from ages 47-59 to 57-69 and identifies midlife characteristics that predict HRQL at older ages.M... | ['Aged', 'Aging', 'Anxiety', 'Body Mass Index', 'Cohort Studies', 'Exercise', 'Female', 'Health Status', 'Humans', 'Middle Aged', 'Multimorbidity', 'Quality of Life', 'Sleep Wake Disorders', 'Smoking', 'Stress, Psychological', 'United States', 'Urinary Incontinence'] | 29,596,565 | [['M01.060.116.100'], ['G07.345.124'], ['F01.470.132'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G11.427.410.698.277', 'I03.350'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and/or arterial thromboembolism. | One hundred and three patients suffering from recurrent venous thrombosis, recurrent arterial thromboembolism and/or recurrent myocardial infarction and 50 healthy subjects were tested for Hageman factor (FXII) coagulant activity and antigen. Among the 103 patients we identified 15 subjects with FXII deficiency (15%), ... | ['Acenocoumarol', 'Administration, Oral', 'Adult', 'Aged', 'Ambulatory Care', 'Factor XII Deficiency', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Phenprocoumon', 'Prevalence', 'Recurrence', 'Risk Factors', 'Thromboembolism'] | 1,440,493 | [['D03.383.663.283.446.520.079', 'D03.633.100.150.446.520.079'], ['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['C15.378.100.100.330', 'C15.378.100.141.330', 'C15.378.463.330', 'C16.320.099.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Views on evidence from nursing and midwifery opinion leaders. | National registration standards in Australia require nurses and midwives to be educationally prepared to use an evidence-based framework for their practice. These standards assume a shared professional understanding of evidence and, an agreed approach towards educational preparation for evidence implementation. In this... | ['Adult', 'Clinical Competence', 'Data Collection', 'Education, Nursing', 'Evidence-Based Nursing', 'Female', 'Humans', 'Interviews as Topic', 'Leadership', 'Male', 'Midwifery', 'New South Wales', 'Nursing', 'Nursing Education Research', 'Qualitative Research'] | 19,464,770 | [['M01.060.116'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['I02.358.462'], ['H02.249.875', 'H02.478.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Lithium kinetics in man: effect of variation in dosage pattern. | 1. Utilizing a general stochastic theory of drug kinetics we have demonstrated that from the serum concentration curve derived from a single dose of lithium, it is possible to predict the steady state concentration, the time required to reach steady state, the dependency of these quantities on the time interval between... | ['Biopharmaceutics', 'Biotransformation', 'Humans', 'Kinetics', 'Lithium', 'Research Design'] | 4,793,335 | [['H01.158.703.003', 'H02.628.049'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['E05.581.500', 'H01.770.644.728']] | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term outcome of children with oesophageal atresia type III. | OBJECTIVE: The aim of this study was to evaluate the outcome of patients with oesophageal atresia type III (EA), focusing on the presence of late sequelae and quality of life.METHODS: This was a retrospective case ascertainment followed by clinical assessment of patients. The study parameters included the patients' dem... | ['Adolescent', 'Child', 'Deglutition Disorders', 'Esophageal Atresia', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Male', 'Nutritional Status', 'Prognosis', 'Quality of Life', 'Respiration Disorders', 'Retrospective Studies'] | 22,753,768 | [['M01.060.057'], ['M01.060.406'], ['C06.405.117.119', 'C09.775.174'], ['C06.198.330', 'C06.405.117.260', 'C16.131.314.330'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.650', 'N01.224.425.525'], ['E01.789'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['C0... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Potential carcinogenic and inhibitory activity of compounds isolated from Lilium candidum L. | This paper deals with determination of potential carcinogenic and inhibitory activity of 10 compounds isolated from the ethanolic extract of Lilium candidum L. perfonned by DC polarography. The series of investigated compounds consisted of two spirostanol saponins, two pyroline derivatives, jatropham and its glucoside,... | ['9,10-Dimethyl-1,2-benzanthracene', 'Animals', 'Anticarcinogenic Agents', 'Carcinogens', 'Ethanol', 'Liliaceae', 'Mice', 'Mutagens', 'Plant Extracts', 'Polarography', 'Pyrroles', 'Saponins', 'Skin Neoplasms', 'Tetradecanoylphorbol Acetate'] | 11,130,250 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D27.888.569.100'], ['D02.033.375'], ['B01.650.940.800.575.912.250.618.875.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.888.569.468'], ['D20.215.784.500', 'D26.667'], ['E05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interest of Youth Living With HIV in Long-Acting Antiretrovirals. | OBJECTIVES: This study's primary objective was to characterize attitudes to long-acting antiretrovirals (LAARV), among youth aged 13-24 years living with perinatally acquired HIV and nonperinatally acquired HIV. Secondary objectives included: assessing whether those with detectable HIV RNA PCR viral load had higher ent... | ['Adolescent', 'Anti-HIV Agents', 'Cross-Sectional Studies', 'Delayed-Action Preparations', 'Female', 'HIV Infections', 'Humans', 'Male', 'Medication Adherence', 'Patient Satisfaction', 'United States', 'Viral Load', 'Young Adult'] | 30,418,298 | [['M01.060.057'], ['D27.505.954.122.388.077.088'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D26.255.210', 'E02.319.300.253'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Signaling through the Inhibitory Fc Receptor FcãRIIB Induces CD8+ | Effector CD8+ T cells are important mediators of adaptive immunity, and receptor-ligand interactions that regulate their survival may have therapeutic potential. Here, we identified a subset of effector CD8+ T cells that expressed the inhibitory fragment crystallizable (Fc) receptor FcãRIIB following activation and mul... | ['Adult', 'Aged', 'Animals', 'Apoptosis', 'CD8-Positive T-Lymphocytes', 'Caspase 3', 'Caspase 7', 'Cell Line, Tumor', 'Female', 'Fibrinogen', 'Graft Rejection', 'Humans', 'Immunoglobulin G', 'Immunosuppression', 'Male', 'Melanoma, Experimental', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Middle Aged', 'Receptors,... | 31,940,267 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['G04.146.954.035'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tension in the culture dish: microfilament organization and migratory behavior of quail neural crest cells. | We have investigated one aspect of the migratory behavior of quail neural crest (NC) cells by comparing the organization of microfilament bundles and the ability to distort migratory substrata by NC, somite, and notochord cells in vitro. In contrast to the numerous cytoplasmic stress fibers in somite-derived fibroblast... | ['Animals', 'Cell Movement', 'Cells, Cultured', 'Cytoskeleton', 'Embryo, Nonmammalian', 'Microscopy, Electron', 'Microscopy, Phase-Contrast', 'Neural Crest', 'Quail'] | 3,891,092 | [['B01.050'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A11.284.430.214.190.750'], ['A13.350', 'A16.331'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.350.515.513.569', 'E05.490.630.569', 'E05.595.513.569'], ['A16.627'], ['B01.050.150.900.248.350.650']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A prospective evaluation of thallium-201 single photon emission computerized tomography for brain tumor burden. | PURPOSE: The follow-up of patients with malignant brain tumors after surgery, radiation, and/or chemotherapy has been inadequate for evaluating brain tumor burden using computerized tomography (CT) or magnetic resonance imaging (MRI). Thallium-201 has been shown to concentrate in viable tumor, and Tl-201 single photon ... | ['Adult', 'Aged', 'Astrocytoma', 'Brain Neoplasms', 'Female', 'Follow-Up Studies', 'Glioblastoma', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prospective Studies', 'Sensitivity and Specificity', 'Thallium Radioisotopes', 'Tomography, Emission-Computed, Single-Photon', 'Tomography, X-Ray Computed'] | 7,721,624 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.557.465.625.600.380.080.335', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis. | Tauhe beta-phosphoglucomutase (beta-PGM) of the haloacid dehalogenase enzyme superfamily (HADSF) catalyzes the conversion of beta-glucose 1-phosphate (betaG1P) to glucose 6-phosphate (G6P) using Asp8 of the core domain active site to mediate phosphoryl transfer from beta-glucose 1,6-(bis)phosphate (betaG1,6bisP) to bet... | ['Amino Acid Substitution', 'Bacterial Proteins', 'Binding Sites', 'Catalysis', 'Catalytic Domain', 'Crystallography, X-Ray', 'Glucose-6-Phosphate', 'Glucosephosphates', 'Kinetics', 'Lactobacillus', 'Models, Molecular', 'Molecular Structure', 'Neisseria meningitidis', 'Phosphotransferases (Phosphomutases)', 'Protein Bi... | 19,154,134 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.776.097'], ['G02.111.570.120'], ['G02.130'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309.742.225'], ['D09.894.417.448.500'], ['D09.894.417.448'], ['G01.374.661', 'G02.111.490'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Primary and secondary tumours occurring simultaneously in the brain of a dog. | Primary brain tumours of a single histological type and metastatic brain tumours are well described in dogs in the current veterinary literature. However, the concurrent presence of a primary and secondary tumour in the brain of a dog has never, to the authors' knowledge, been previously reported. The clinical and path... | ['Adenocarcinoma', 'Animals', 'Brain Neoplasms', 'Diagnosis, Differential', 'Dog Diseases', 'Dogs', 'Fatal Outcome', 'Female', 'Mammary Neoplasms, Animal', 'Neoplasm Metastasis', 'Oligodendroglioma'] | 17,004,954 | [['C04.557.470.200.025'], ['B01.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.171'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C04.588.531', 'C22.520'], ['C04... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Most Enterobacter aerogenes strains in France belong to a prevalent clone. | The aim of this study was to determine the distribution in France of the Enterobacter aerogenes prevalent clone isolated in the hospitals of the Marseille area (A. Davin-Regli, D. Monnet, P. Saux, C. Bosi, R. Charrel, A. Barthelemy, and C. Bollet, J. Clin. Microbiol. 34:1474-1480, 1996). A total of 123 E. aerogenes iso... | ['Bacterial Outer Membrane Proteins', 'Demography', 'Enterobacter', 'Enterobacteriaceae Infections', 'France', 'Humans', 'Introns', 'Laboratories, Hospital', 'Plasmids', 'Polymerase Chain Reaction', 'Random Amplified Polymorphic DNA Technique', 'Reproducibility of Results', 'beta-Lactamases'] | 10,364,580 | [['D12.776.097.120', 'D12.776.543.100'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B03.440.450.425.275', 'B03.660.250.150.170'], ['C01.150.252.400.310'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['N02.278.216.500.968.420', 'N02.278.... | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Help and care participation of spouses and children of aged persons who return to homes for the aged and long term care facilities]. | This study investigates the participation of family caregivers when an elderly relative is going to a nursing home. Twenty-two primary caregivers, whose relative, aged 60 years or older, had recently been admitted to a public nursing home, were interviewed. The content analysis reveals that caregivers worry about and d... | ['Adult', 'Aged', 'Caregivers', 'Female', 'Homes for the Aged', 'Humans', 'Long-Term Care', 'Male', 'Middle Aged'] | 15,310,091 | [['M01.060.116'], ['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.476', 'N02.421.585.476'], ['M01.060.116.630']] | ['Named Groups [M]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Outcomes of Bordetella infections in vaccinated children: effects of bacterial number in the nasopharynx and patient age. | Five outbreaks of infection (three pertussis, one parapertussis, and one mixed) in schools were studied prospectively. Nasopharyngeal swabs were obtained from a total of 697 children for culture of Bordetella organisms. Of 50 vaccinated children with culture-confirmed Bordetella infections (29 with pertussis and 21 par... | ['Adolescent', 'Age Factors', 'Bordetella Infections', 'Child', 'Colony Count, Microbial', 'Disease Outbreaks', 'Female', 'Humans', 'Immunity', 'Male', 'Nasopharynx', 'Respiratory System', 'Time Factors', 'Treatment Outcome', 'Vaccination'] | 10,391,857 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C01.150.252.400.143'], ['M01.060.406'], ['E01.370.225.875.220', 'E05.200.875.220'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['A04.623.557', 'A14.724.557'], ['A04'], ['G01.910.857'], ['E01.789.800', 'N04.761.559.590.800', ... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multi-purpose ECG telemetry system. | BACKGROUND: The Electrocardiogram ECG is one of the most important non-invasive tools for cardiac diseases diagnosis. Taking advantage of the developed telecommunication infrastructure, several approaches that address the development of telemetry cardiac devices were introduced recently. Telemetry ECG devices allow eas... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Arrhythmias, Cardiac', 'Child', 'Child, Preschool', 'Electrocardiography', 'Electrodes', 'Equipment Design', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Signal Processing, Computer-Assisted', 'Signal-To-Noise Ratio', 'Telemedicine', 'Telemetry', 'Young... | 28,629,374 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067', 'C23.550.073'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E07.305.250'], ['E05.320'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
AFM imaging of milk casein micelles: evidence for structural rearrangement upon acidification. | Milk casein micelles are natural association colloids that we all encounter in everyday life, yet we still lack an accurate description of their internal structure and the interactions that stabilize it. In this letter, we provide for the first time detailed images of intact casein micelles as obtained through atomic f... | ['Acids', 'Animals', 'Caseins', 'Cattle', 'Hydrogen-Ion Concentration', 'Micelles', 'Microscopy, Atomic Force', 'Milk'] | 22,384,811 | [['D01.029'], ['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.649.313.500.380.271'], ['G02.300'], ['D05.374', 'D26.255.560'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Identification of probable early-onset biomarkers for tuberculosis disease progression. | Determining what constitutes protective immunity to TB is critical for the development of improved diagnostics and vaccines. The comparison of the immune system between contacts of TB patients, who later develop TB disease (progressors), versus contacts who remain healthy (non-progressors), allows for identification of... | ['Adult', 'Biomarkers', 'Cells, Cultured', 'Cytokines', 'Female', 'Flow Cytometry', 'Humans', 'Leukocytes, Mononuclear', 'Male', 'Middle Aged', 'RNA', 'Tuberculosis', 'Young Adult'] | 21,966,464 | [['M01.060.116'], ['D23.101'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fetal intestinal transplant model for mucosal immune responses. | A rat fetal intestinal transplant model was developed for long-term study of intestinal immune responses. For the model, fetal small intestine is transplanted into the dorsal subcutaneous tissue of syngeneic adults and allowed to mature, providing an accessible site, isolated from the intestinal stream. We previously d... | ['Animals', 'Bacteria', 'Cholera Toxin', 'Female', 'Fetus', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunologic Memory', 'Intestinal Mucosa', 'Intestine, Small', 'Lipopolysaccharides', 'Models, Biological', 'Pregnancy', 'Rats', 'Rats, Inbred F344'] | 2,033,272 | [['B01.050'], ['B03'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['A16.378'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[China Guideline for Diagnosis and Treatment of Incisional Hernia (2018 edition)]. | Abdominal incisional hernia is the result of the loss of the integrity and tension balance of the abdominal wall. According to clinical manifestation and physical examination, most incisional hernia can be clearly diagnosed. For small and concealed incisional hernia, the diagnosis can be confirmed by imaging examinatio... | ['Abdominal Wall', 'China', 'Hernia, Ventral', 'Herniorrhaphy', 'Humans', 'Incisional Hernia', 'Recurrence', 'Surgical Mesh'] | 30,051,436 | [['A01.923.047.050'], ['Z01.252.474.164'], ['C23.300.707.374.937'], ['E04.680.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.707.945', 'C23.550.767.500'], ['C23.550.291.937'], ['E07.858.708']] | ['Anatomy [A]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Laparoscopic ovarian diathermy after clomiphene failure in polycystic ovary syndrome: is it worthwhile? A randomized controlled trial. | PURPOSE: Laparoscopic ovarian diathermy (LOD) represents a successful treatment option for women with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS). However, in case of CC failure PCOS, LOD offers several theoretical advantages. This study was conducted to compare the efficacy of LOD versus continu... | ['Adult', 'Clomiphene', 'Diathermy', 'Endometrium', 'Female', 'Fertility Agents, Female', 'Humans', 'Infertility, Female', 'Laparoscopy', 'Polycystic Ovary Syndrome', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Rate', 'Treatment Failure', 'Young Adult'] | 21,755,338 | [['M01.060.116'], ['D02.455.426.559.389.150.700.125'], ['E02.565.280'], ['A05.360.319.679.490'], ['D27.505.696.875.552.344', 'D27.505.954.705.552.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C04.182.612.765', 'C13.351.500.056.630.580.765'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Frequency of apnea, bradycardia, and desaturations following first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B immunization in hospitalized preterm infants. | BACKGROUND: Adverse cardiorespiratory events including apnea, bradycardia, and desaturations have been described following administration of the first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae type B (DTP-IPV-Hib) immunization to preterm infants. The effect of the recent substitution of acel... | ['Alberta', 'Apnea', 'Birth Weight', 'Body Weight', 'Bradycardia', 'Child, Hospitalized', 'Cohort Studies', 'Diphtheria-Tetanus-Pertussis Vaccine', 'Female', 'Gestational Age', 'Haemophilus Vaccines', 'Humans', 'Hypoxia', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases',... | 16,784,533 | [['Z01.107.567.176.064'], ['C08.618.085', 'C23.888.852.130'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C1... | ['Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The Clinical Impact and Cost Effectiveness of Quadrivalent Versus Trivalent Influenza Vaccination in Finland. | BACKGROUND: Trivalent influenza vaccines encompass one influenza B lineage; however, predictions have been unreliable on which of two antigenically distinct circulating lineages will dominate. Quadrivalent seasonal influenza vaccines contain strains from both lineages. This analysis assesses the cost effectiveness of s... | ['Adolescent', 'Child', 'Child, Preschool', 'Cost-Benefit Analysis', 'Finland', 'Hospitalization', 'Humans', 'Immunity, Herd', 'Influenza Vaccines', 'Influenza, Human', 'Models, Economic', 'Vaccination', 'Vaccines, Attenuated', 'Vaccines, Inactivated'] | 27,423,657 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.125'], ['Z01.542.816.186'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.400'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['E05.318.740.500.600', 'E05.599.835.890... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Simultaneous determination of five phthalate esters and bisphenol A in milk by packed-nanofiber solid-phase extraction coupled with gas chromatography and mass spectrometry. | A novel polystyrene/pyridine composite nanofiber was synthesized and utilized as the sorbent material for the solid-phase extraction of bisphenol A and five common phthalate esters in milk. The method of extraction integrated extraction and preconcentration of target analytes into a single step. Bisphenol A and five co... | ['Animals', 'Benzhydryl Compounds', 'Esters', 'Gas Chromatography-Mass Spectrometry', 'Milk', 'Nanofibers', 'Phenols', 'Phthalic Acids', 'Solid Phase Extraction'] | 30,556,655 | [['B01.050'], ['D02.455.426.559.389.115'], ['D02.241.400'], ['E05.196.181.349.500', 'E05.196.566.500'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['J01.637.512.300'], ['D02.455.426.559.389.657'], ['D02.241.223.805'], ['E05.196.155.800']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[The Italian Fanconi Anemia Registry]. | The Italian Registry of Fanconi's Anaemia (RIAF) was established in 1994 at the Cytogenetics Department of the Elena d'Aosta Hospital in Naples. Its aim is to collect data regarding Italian Fanconi's anaemia (FA) patients and their relatives. Since FA is a rare disease, the Registry is expected to benefit patients, imp... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Fanconi Anemia', 'Female', 'Humans', 'Infant', 'Italy', 'Male', 'Registries'] | 10,645,656 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C15.378.071.085.080.280', 'C15.378.190.223.500.500.280', 'C16.320.077.280', 'C18.452.284.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.542.489'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', ... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The variation of isometric energy rates with muscle length: a distribution-moment model analysis. | The Distribution-Moment Model of skeletal muscle, which has been enhanced recently to make possible the calculation of chemical energy release (E) and heat production (H) rates [1], is applied to isometric muscle. Under steady-state isometric conditions the model predicts a simple relation between the energy rates and ... | ['Biomechanical Phenomena', 'Body Temperature Regulation', 'Energy Metabolism', 'Humans', 'Isometric Contraction', 'Models, Theoretical'] | 1,487,910 | [['G01.154.090', 'G01.374.089'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G03.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['E05.599']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distributed nonlinear fiber chirped-pulse amplifier system. | A two-stage fiber-based femtosecond amplification system is presented, based on chirped-pulse amplification in highly nonlinear regime. The amount of self-phase modulation is separately adjusted in each stage selecting the proper stretching ratio in order to compensate gain narrowing. Analytical design rules are valida... | ['Aluminum Oxide', 'Amplifiers, Electronic', 'Computer Simulation', 'Computer-Aided Design', 'Equipment Design', 'Fiber Optic Technology', 'Ions', 'Models, Theoretical', 'Optics and Photonics', 'Oscillometry', 'Signal Processing, Computer-Assisted', 'Ytterbium'] | 19,550,483 | [['D01.056.050', 'D01.650.550.050'], ['E07.305.061'], ['L01.224.160'], ['L01.224.108.150', 'L01.296.110.150'], ['E05.320'], ['H01.671.617.249'], ['D01.248.497'], ['E05.599'], ['H01.671.617', 'J01.293.688'], ['E05.654'], ['L01.224.800'], ['D01.268.558.362.992', 'D01.552.550.399.992']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Controlling alcohol-related violence: a treatment programme. | INTRODUCTION: Control Of Violence for Angry Impulsive Drinkers (COVAID) is a structured, cognitive-behavioural treatment programme for people in the community. The importance of the programme is that it addresses the link between two major problems areas--drinking and aggression--while emphasizing the reduction of the ... | ['Adult', 'Aggression', 'Alcoholic Intoxication', 'Cognitive Behavioral Therapy', 'Humans', 'Male', 'Pilot Projects', 'Treatment Outcome', 'Violence'] | 14,624,272 | [['M01.060.116'], ['F01.145.126.125', 'F01.145.813.045'], ['C25.775.100.175', 'F03.900.100.300'], ['F04.754.137.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['I... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Influence of irrigation conditions in the germination of plasma treated Nasturtium seeds. | Plasma treatments had emerged as a useful technique to improve seed germination. In this work we investigate the influence of different irrigation conditions and plasma treatments on the germination of nasturtium seeds. During plasma treatment, seeds experience a progressive weight loss as a function of treatment time ... | ['Agricultural Irrigation', 'Germination', 'Nasturtium', 'Plasma Gases', 'Seeds', 'Temperature', 'Water'] | 30,401,893 | [['J01.040.044'], ['G07.345.625.249', 'G15.357'], ['B01.650.940.800.575.912.250.157.644'], ['D01.362.740'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D01.045.250.875', 'D01.248.497.158.459.650... | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[The germinal population at embryonic stage and young age in the female hybrid duck born of male Pekin x female Barbary crossing. Comparison with ducks of the parent species]. | As hatching the number of left ovary germinal cells of the female hybrid (Anas platyrhynchos x Cairina moschata) is weaker than that of the Peking and Barbary females because the small size of the genital crest limites the number of colonising germinal cells. As well after 16 days of incubation the multiplication of th... | ['Age Factors', 'Animals', 'Ducks', 'Female', 'Hybridization, Genetic', 'Male', 'Ovary'] | 142,551 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['E05.820.150.390', 'G05.090.390'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497']] | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Electrospinning of zein-ethyl cellulose hybrid nanofibers with improved water resistance for food preservation. | Zein electrospun nanofibers have poor water resistance, which restricts its applications in food preservation. To improve the water resistance of nanofibers, zein/ethyl cellulose (EC) hybrid nanofibers were prepared at different ratios. Besides, we also encapsulated cinnamon essential oil (CEO) into electrospun fibers ... | ['Agaricus', 'Cellulose', 'Electricity', 'Food Packaging', 'Food Preservation', 'Hydrogen Bonding', 'Nanofibers', 'Water', 'Zein'] | 31,739,036 | [['B01.300.179.100.105'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['G01.358.500.249'], ['J01.576.423.200.375', 'J01.576.423.850.600', 'J01.576.761.400'], ['J01.576.423.850.700'], ['G02.282'], ['J01.637.512.300'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Functional analysis of a mammalian odorant receptor subfamily. | Phylogenetic analysis groups mammalian odorant receptors into two broad classes and numerous subfamilies. These subfamilies are proposed to reflect functional organization. Testing this idea requires an assay allowing detailed functional characterization of odorant receptors. Here we show that a variety of Class I and ... | ['Animals', 'Biological Assay', 'Cell Membrane', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Dicarboxylic Acids', 'Female', 'Gene Expression', 'Mammals', 'Membrane Potentials', 'Mice', 'Molecular Structure', 'Molecular Weight', 'Multigene Family', 'Oocytes', 'Patch-Clamp Techniques', 'RNA, Messenger', 'Rece... | 16,606,354 | [['B01.050'], ['E05.091'], ['A11.284.149'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500', 'D12.776.543.585.400.175.125', 'D12.776.543.585.450.074.500.500.500.500'], ['D02.241.081.337'], ['G05.297'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unexplained severe chronic pain in general practice. | The aim of this study was to estimate the prevalence of unexplained severe chronic pain (USCP) in general practice and to report medical as well as psychological descriptions of patients suffering from this condition.A total of 45 GPs in 35 different practices included patients throughout the year 1996. Patients were i... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Chronic Disease', 'Family Practice', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mood Disorders', 'Musculoskeletal Diseases', 'Netherlands', 'Pain', 'Pain Measurement', 'Patient Acceptance of Health Care', 'Prevalence', 'Problem Solving', 'Sick Role', 'Social Support'] | 12,036,307 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.500'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.600'], ['C05'], ['Z01.542.651'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E01.370.600.550.324'], ['F01.100.150.750.500', 'F01.145.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenome... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Extension of the lifespan of cultured normal human diploid cells by vitamin E. | Inclusion of vitamin E (DL-alpha-tocopherol) in the culture medium for human diploid cells greatly prolongs their in vitro lifespan. The addition of 100 mug of DL-alpha-tocopherol per ml of medium has allowed us to culture WI-38 cells for more than 100 population doublings to date. (These cells normally have an in vitr... | ['Cell Division', 'Cell Line', 'Cell Survival', 'DNA', 'Diploidy', 'Fibroblasts', 'Humans', 'Karyotyping', 'Lung', 'Mitosis', 'Subcellular Fractions', 'Thymidine', 'Tritium', 'Vitamin E'] | 4,531,015 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['G04.346'], ['D13.444.308'], ['G05.700.264'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['A04.411'], ['G04.144.22... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Freezing and freeze-drying of the bacterium Rahnella aquatilis BNM 0523: study of protecting agents, rehydration media and freezing temperatures. | AIMS: The aim of the present study was to evaluate and compare freezing and freeze-drying treatments for conserving Rahnella aquatilis (BNM 0523) with the goal to achieve an adequate commercial formulation of this biocontrol agent.METHODS AND RESULTS: The effect of several protective agents, rehydration media and freez... | ['Antibiosis', 'Botrytis', 'Cold Temperature', 'Fluid Therapy', 'Food Preservation', 'Freeze Drying', 'Freezing', 'Humans', 'Malus', 'Microbial Interactions', 'Rahnella'] | 21,913,947 | [['G06.550.050', 'G16.062'], ['B01.300.381.128'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E02.319.360'], ['J01.576.423.850.700'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', '... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Environmental xenoestrogens, antiandrogens and disorders of male sexual differentiation. | Over the past 20 years, the documented increase in the disorders of male sexual differentiation, such as hypospadias, cryptorchidism, and micropenis, has led to the suspicion that environmental chemicals are detrimental to normal male genital development in utero. Male sexual differentiation is critically dependent on ... | ['Androgen Antagonists', 'Cell Line', 'Diethylstilbestrol', 'Disorders of Sex Development', 'Estrogens, Non-Steroidal', 'Female', 'Genes, Reporter', 'Humans', 'Luminescent Measurements', 'Male', 'Pregnancy', 'Prostate', 'Receptors, Androgen'] | 11,403,899 | [['D06.347.065', 'D27.505.696.399.450.065'], ['A11.251.210'], ['D02.455.426.559.389.150.700.725.500'], ['C12.706.316', 'C13.351.875.253', 'C16.131.939.316', 'C19.391.119'], ['D27.505.696.399.472.277.540'], ['G05.360.340.024.340.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.516'], ['G08.686.784.7... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Budget crisis: how six Ontario CEOs erased their deficits. | Earlier this year, about half of Ontario's 222 hospitals faced a funding crisis. In the spring, Ontario's treasurer read the riot act: the province wouldn't bail out hospitals with deficits. It was the first time any Ontario government followed through on its commitment to slash hospital costs. A recent report based on... | ['Budgets', 'Financial Management', 'Financial Management, Hospital', 'Health Facility Administrators', 'Hospital Administrators', 'Ontario'] | 10,290,730 | [['N03.219.463.060'], ['N03.219.463'], ['N02.278.216.500.875', 'N03.219.463.280', 'N04.452.442.452.180'], ['M01.526.070.490', 'M01.526.485.430', 'N02.360.430'], ['M01.526.070.490.490', 'M01.526.485.430.490', 'M01.526.485.740.380', 'N02.360.430.490', 'N02.360.740.380'], ['Z01.107.567.176.639']] | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Differences in Muscle O2 | The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest... | ['Adult', 'Exercise', 'Exercise Test', 'Female', 'Hemoglobins', 'Humans', 'Muscle, Skeletal', 'Overweight', 'Oxygen Consumption'] | 31,893,414 | [['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567', 'A10.690.552.500'], ['C23.888.144.699', 'E01.370.600.115.100.160.120.699', 'G07.100.100.160.12... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Diversity of fast myosin heavy chain expression during development of gastrocnemius, bicep brachii, and posterior latissimus dorsi muscles in normal and dystrophic chickens. | The expression of fast myosin heavy chain (MHC) isoforms was examined in developing bicep brachii, lateral gastrocnemius, and posterior latissimus dorsi (PLD) muscles of inbred normal White Leghorn chickens (Line 03) and genetically related inbred dystrophic White Leghorn chickens (Line 433). Utilizing a highly charact... | ['Age Factors', 'Animals', 'Antibodies, Monoclonal', 'Blotting, Western', 'Cell Differentiation', 'Chick Embryo', 'Chickens', 'Epitopes', 'Immunoenzyme Techniques', 'Muscular Dystrophy, Animal', 'Myosins', 'Peptide Mapping'] | 2,460,389 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.152'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350... | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The alcohol use disorder and associated disabilities interview schedule (AUDADIS): reliability of alcohol and drug modules in a clinical sample. | The alcohol use disorder and associated disabilities interview schedule (AUDADIS), was designed for use in the general population, and was previously shown to have good reliability in a sample of household residents. However, measurement problems are different in clinical samples. Thus, a test-retest study was conducte... | ['Adolescent', 'Adult', 'Alcoholism', 'Comorbidity', 'Disability Evaluation', 'Female', 'Humans', 'Illicit Drugs', 'Male', 'Mental Disorders', 'Middle Aged', 'Personality Assessment', 'Psychometrics', 'Psychotropic Drugs', 'Reproducibility of Results', 'Substance-Related Disorders'] | 9,088,785 | [['M01.060.057'], ['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['N05.715.350.225', 'N06.850.490.687'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['F03'], ['M01.060.116.630'], ['F04.513'], ['F04.711.780'], ['D27.505.954.427.700'], ['E05.318.370.725', 'E05.337.851', 'N05.7... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Patients' attitudes toward health care providers collecting information about their race and ethnicity. | BACKGROUND: Experts recommend that health care providers (HCPs) collect patients' race/ethnicity, but HCPs worry that this may alienate patients.OBJECTIVE: To determine patients' attitudes toward HCPs collecting race/ethnicity data.DESIGN: Cross-sectional survey.PARTICIPANTS: General Internal Medicine patients (n=220).... | ['Attitude to Health', 'Continental Population Groups', 'Cross-Sectional Studies', 'Ethnic Groups', 'Health Personnel', 'Humans', 'Professional-Patient Relations', 'Surveys and Questionnaires'] | 16,191,134 | [['F01.100.150', 'N05.300.150'], ['M01.686.508'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['M01.686.754', 'N01.224.317'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650', 'N05.300.660'], ['E05.318.308.980', 'N05.715.360.300.800', 'N0... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An RbAp48-like gene regulates adult stem cells in planarians. | Retinoblastoma-associated proteins 46 and 48 (RbAp46 and RbAp48) are factors that are components of different chromatin-modelling complexes, such as polycomb repressive complex 2, the activity of which is related to epigenetic gene regulation in stem cells. To date, no direct findings are available on the in vivo role ... | ['Animals', 'Apoptosis', 'Cell Differentiation', 'Chromatin', 'Flow Cytometry', 'Helminth Proteins', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Microscopy, Electron, Transmission', 'Planarians', 'RNA Interference', 'Retinoblastoma-Binding Protein 4', 'Reverse Transcriptase Polymerase Chain Reaction', '... | 20,124,416 | [['B01.050'], ['G04.146.954.035'], ['G04.152'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D12.776.419'], ['B01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
What Healthcare Will Look Like in the Next Five Years. | With the 2016 election now in the past, everyone is wondering and predicting what will happen next. I have heard everything from fearful Democrats saying the new President will abolish Obamacare and throw 20 million people out in the cold and return them to the ranks of the uninsured to optimistic Republicans making st... | ['Delivery of Health Care', 'Economic Recession', 'Forecasting', 'Health Care Costs', 'Health Policy', 'Humans', 'Patient Protection and Affordable Care Act', 'Politics', 'United States'] | 30,047,702 | [['N04.590.374', 'N05.300'], ['I01.261.425'], ['I01.320'], ['N03.219.151.400', 'N05.300.375'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.918', 'N03.706.615.806'], ['I01.738'], ['Z01.107.567.875']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Traditional herbal medicines worldwide, from reappraisal to assessment in Europe. | Since 2004 the regulatory framework within the European Union has a specific assessment procedure for herbal medicinal products, with a medicinal use based on traditional practice. The main requirement concerning the traditional use is focussed on the period of time for medical use: at least 30 years, including 15 year... | ['European Union', 'Humans', 'Legislation, Drug', 'Medicine, Traditional', 'Phytotherapy', 'Plant Preparations', 'Time Factors'] | 25,043,781 | [['I01.615.500.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.605', 'N03.706.615.402'], ['E02.190.488', 'I01.076.201.450.654'], ['E02.190.755'], ['D20.215.784'], ['G01.910.857']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Lower levels of whole blood LPS-stimulated cytokine release are associated with poorer clinical outcomes in surgical ICU patients. | BACKGROUND: In vitro pretreatment of human monocytes with lipopolysaccharide (LPS) induces "endotoxin tolerance" with blunted TNF and IL-6 release to rechallenge with LPS. The pro-inflammatory cytokines TNF and IL-6 are important mediators in sepsis. A high IL-6 concentration has been used as a marker of infection seve... | ['Adult', 'Critical Care', 'Humans', 'In Vitro Techniques', 'Interleukin-6', 'Lipopolysaccharides', 'Middle Aged', 'Outcome Assessment, Health Care', 'Predictive Value of Tests', 'Severity of Illness Index', 'Tumor Necrosis Factor-alpha'] | 12,906,717 | [['M01.060.116'], ['E02.760.190', 'N02.421.585.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['M01.060.116.630'], ['H01.770.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Preslaughter holding environment in pork plants is highly contaminated with Salmonella enterica. | The objective of this study was to determine whether abattoir pens can provide a Salmonella enterica infection source during the 2 to 4 h of preharvest holding. Previous work has suggested that pigs may be getting infected, but little has been reported on the environmental contamination of abattoir holding pens. For 24... | ['Animals', 'Environmental Microbiology', 'Meat', 'Salmonella enterica', 'Swine'] | 12,902,233 | [['B01.050'], ['H01.158.273.540.274', 'N06.850.425'], ['G07.203.300.600', 'J02.500.600'], ['B03.440.450.425.800.200', 'B03.660.250.150.710.160'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Subjective perceptions and psychological distress associated with the deep underground: A cross-sectional study in a deep gold mine in China. | This study reports the subjective perceptions and mental state of employees working in the Erdaogou Mine, affiliated with Jiapigou Minerals Limited Corporation of China National Gold Group Corporation (CJEM); these employees are pioneers working at the deepest point below ground in China. The data represent a valuable ... | ['Adult', 'Air Pressure', 'China', 'Confined Spaces', 'Cross-Sectional Studies', 'Gold', 'Humans', 'Humidity', 'Male', 'Middle Aged', 'Mining', 'Occupational Exposure', 'Occupational Stress', 'Oxygen', 'Perception', 'Radiation Exposure', 'Temperature', 'Workplace', 'Young Adult'] | 31,145,277 | [['M01.060.116'], ['G16.500.750.274.100', 'N06.230.300.100.185.100'], ['Z01.252.474.164'], ['G16.500.275.074', 'N06.230.074'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
HipHop interacts with HOAP and HP1 to protect Drosophila telomeres in a sequence-independent manner. | Telomeres prevent chromosome ends from being repaired as double-strand breaks (DSBs). Telomere identity in Drosophila is determined epigenetically with no sequence either necessary or sufficient. To better understand this sequence-independent capping mechanism, we isolated proteins that interact with the HP1/ORC-associ... | ['Animals', 'Binding Sites', 'Cell Line', 'Chromosomal Proteins, Non-Histone', 'Drosophila', 'Drosophila Proteins', 'Drosophila melanogaster', 'Evolution, Molecular', 'Genes, Insect', 'Multiprotein Complexes', 'Mutation', 'Protein Structure, Tertiary', 'Protein Subunits', 'RNA Interference', 'Telomere'] | 20,057,353 | [['B01.050'], ['G02.111.570.120'], ['A11.251.210'], ['D12.776.660.235', 'D12.776.664.235'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.340', 'G05.360.340.357.500'], ['D05.500'], ['G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Basic image analysis and manipulation in ImageJ. | Image analysis methods have been developed to provide quantitative assessment of microscopy data. In this unit, basic aspects of image analysis are outlined, including software installation, data import, image processing functions, and analytical tools that can be used to extract information from microscopy data using ... | ['Computational Biology', 'Image Processing, Computer-Assisted', 'Internet', 'Microscopy', 'Microscopy, Fluorescence', 'Reproducibility of Results', 'Software'] | 23,547,012 | [['H01.158.273.180', 'L01.313.124'], ['L01.224.308'], ['L01.224.230.110.500'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['E01.370.350.515.458', 'E05.595.458'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['L01.224.900']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
An exploration of family dynamics and attachment strategies in a family with ADHD/conduct problems. | This article reports the preliminary findings of a study of attachment patterns and relationship themes using the TAAI (Transition to Adulthood Attachment Interview), AAI (Adult Attachment Interview) and family interviews (based on the first of 15 families). Research data is presented on a young man aged 16 with a diag... | ['Adolescent', 'Adult', 'Attention Deficit and Disruptive Behavior Disorders', 'Family Conflict', 'Family Relations', 'Female', 'Humans', 'Interview, Psychological', 'Male', 'Object Attachment'] | 21,565,873 | [['M01.060.057'], ['M01.060.116'], ['F03.625.094'], ['F01.829.263.370.054', 'F01.829.401.142'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['F02.739.794.624']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway. | In neurons, up-regulation of Notch activity either inhibits neurite extension or causes retraction of neurites. Conversely, inhibition of Notch1 facilitates neurite extension. Acid-sensing ion channels (ASICs) are a family of proton-gated cation channels, which play critical roles in synaptic plasticity, learning and m... | ['Acid Sensing Ion Channels', 'Animals', 'Cell Line, Tumor', 'Cyclic AMP', 'Dipeptides', 'Down-Regulation', 'Gene Expression Regulation, Neoplastic', 'Mice', 'Neurites', 'Neuroblastoma', 'Neuronal Outgrowth', 'RNA Interference', 'Receptor, Notch1', 'Signal Transduction', 'Time Factors', 'Transfection'] | 28,030,818 | [['D12.776.157.530.400.875.050', 'D12.776.543.550.450.875.050', 'D12.776.543.585.400.875.050', 'D12.776.631.024'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.644.456.345'], ['G02.111.240', 'G05.308.200', 'G... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Group life review and denial of death. | In order to assess the utility of structured reminiscing with the elderly a series of five Life Review Workshops (LRW) were offered. Sixty-three seniors participated in the treatment or no-treatment conditions and were administered four attitude measures pre- and post-treatment. Workshop participants also filled out a ... | ['Aged', 'Attitude to Death', 'Chicago', 'Humans', 'Life Change Events', 'Statistics as Topic'] | 10,264,979 | [['M01.060.116.100'], ['F01.100.125', 'N05.300.125'], ['Z01.107.567.875.350.350.200', 'Z01.107.567.875.510.350.200', 'Z01.433.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Second messenger Ap4 | Signal transduction systems enable organisms to monitor their external environments and accordingly adjust the cellular processes. In mast cells, the second messenger Ap4A binds to the histidine triad nucleotide-binding protein 1 (HINT1), disrupts its interaction with the microphthalmia-associated transcription factor ... | ['Cell Line', 'Crystallography, X-Ray', 'Dinucleoside Phosphates', 'Gene Knockdown Techniques', 'Mast Cells', 'Microphthalmia-Associated Transcription Factor', 'Nerve Tissue Proteins', 'Polymerization', 'Protein Structure, Tertiary', 'Signal Transduction'] | 31,604,935 | [['A11.251.210'], ['E05.196.309.742.225'], ['D13.695.250'], ['E05.393.335.500'], ['A11.329.427', 'A15.382.652'], ['D12.776.260.103.500.500', 'D12.776.260.108.092.500', 'D12.776.930.125.500.500', 'D12.776.930.127.092.500'], ['D12.776.631'], ['G02.750'], ['G02.111.570.820.709.610'], ['G02.111.820', 'G04.835']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Further study of hepatitis C virus RNA detection in formalin-fixed, paraffin-embedded liver tissues by ligation-dependent polymerase chain reaction. | Ligation-dependent polymerase chain reaction (LD-PCR) is a novel, simple and sensitive PCR assay that could be useful for the molecular diagnosis of various viral infections. This assay uses two capture probes for RNA isolation and two hemiprobes for the subsequent PCR. To investigate its usefulness in the field of pat... | ['Adult', 'Aged', 'Base Sequence', 'Carcinoma, Hepatocellular', 'DNA Primers', 'DNA Probes', 'Formaldehyde', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Liver', 'Liver Neoplasms', 'Middle Aged', 'Molecular Sequence Data', 'Paraffin Embedding', 'Polymerase Chain Reaction', 'RNA, Viral', 'Tissue Fixation'] | 9,702,854 | [['M01.060.116'], ['M01.060.116.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Retinal masking during pursuit eye movements: implications for spatiotopic visual persistence. | White (1976) reported that presentation of a masking stimulus during a pursuit eye movement interfered with the perception of a target stimulus that shared the same spatial, rather than retinal, coordinates as the mask. This finding has been interpreted as evidence for the existence of spatiotopic visual persistence. W... | ['Discrimination Learning', 'Eye Movements', 'Humans', 'Orientation', 'Pattern Recognition, Visual', 'Perceptual Masking', 'Pursuit, Smooth', 'Retina', 'Space Perception'] | 2,951,486 | [['F02.463.425.280'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.071.594', 'F02.463.593.932.733', 'G07.888.125.594'], ['G14.350.453'], ['A09.371.729'], ['F02.463.593.778']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laparoscopic resection for colorectal polyps: a single institution experience. | BACKGROUND: Endoscopic polypectomy, although routinely used for the treatment of colorectal polyps, may be limited by polyp size, location and histology. Laparoscopic resection for malignant polyps and polyps not amenable to endoscopic removal has the advantage of adequate disease clearance as well as the short-term be... | ['Adult', 'Aged', 'Aged, 80 and over', 'Colonic Polyps', 'Female', 'Follow-Up Studies', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Prospective Studies', 'Rectal Neoplasms', 'Treatment Outcome', 'Young Adult'] | 21,418,473 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.825.411.235'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['E05.318.372.500.750.625'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mucin-producing signet ring cell adenoma of the thyroid. | Signet ring cell adenoma of the thyroid, though rare, is well documented. This change is chiefly due to intracellular accumulation of thyroglobulin that appears mucinous. Awareness of this entity is important as it may closely simulate a metastatic mucin-secreting signet ring cell carcinoma. Although the mucinous mater... | ['Adenoma', 'Cell Nucleus', 'Humans', 'Male', 'Middle Aged', 'Mucins', 'Thyroid Gland', 'Thyroid Neoplasms'] | 19,008,577 | [['C04.557.470.035'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.395.560.631'], ['A06.300.900'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Time-based event expectations employ relative, not absolute, representations of time. | When the timing of an event is predictable, humans automatically form implicit time-based event expectations. We investigated whether these expectations rely on absolute (e.g., 800 ms) or relative (e.g., a shorter duration) representations of time. In a choice-response task with two different pre-target intervals, part... | ['Adult', 'Association Learning', 'Executive Function', 'Female', 'Humans', 'Male', 'Psychomotor Performance', 'Time Perception', 'Young Adult'] | 25,112,395 | [['M01.060.116'], ['F02.463.425.069.296'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F02.463.593.857'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cost utility evaluation of extracorporeal membrane oxygenation as a bridge to transplant for children with end-stage heart failure due to dilated cardiomyopathy. | BACKGROUND: Extracorporeal membrane oxygenation (ECMO) and cardiac transplantation are recognized to be expensive.METHODS: We performed a cost utility evaluation with a decision model approach, including 75 children with dilated cardiomyopathy. A cohort of patients with end stage heart failure who were offered ECMO bri... | ['Adolescent', 'Arrhythmias, Cardiac', 'Cardiomyopathy, Dilated', 'Child', 'Child, Preschool', 'Cost-Benefit Analysis', 'Costs and Cost Analysis', 'Critical Care', 'Extracorporeal Membrane Oxygenation', 'Health Status', 'Heart Arrest', 'Heart Failure', 'Heart Transplantation', 'Humans', 'Life Expectancy', 'Markov Chain... | 19,134,528 | [['M01.060.057'], ['C14.280.067', 'C23.550.073'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.125'], ['N03.219.151'], ['E02.760.190', 'N02.421.585.190'], ['E02.880.301', 'E04.292.451'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['C14.280.38... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Sense and nonsense in the treatment of exocrine pancreatic insufficiency]. | Application of pancreatic digestive enzymes is indicated in cases of a quantitatively decreased exogenous secretion or an asynchronous secretion of enzymes with regard to the duodenal passage of chyme. A clear indication for therapy is a proven steatorrhea, a relative indication loss weight of and/or uncharacteristic a... | ['Cholecystokinin', 'Enzyme Therapy', 'Exocrine Pancreatic Insufficiency', 'Humans', 'Lipase', 'Pain Management', 'Pancreas', 'Pancreatic Diseases', 'Pancreatin', 'Pancreatitis'] | 8,091,057 | [['D06.472.317.152', 'D12.644.120'], ['E02.319.353'], ['C06.689.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.352.100.400'], ['E02.745', 'N04.590.607.500'], ['A03.734'], ['C06.689'], ['D08.811.277.610', 'D20.777.500.720'], ['C06.689.750']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A new dineolignan from Saururus chinensis root. | A new tetrahydrofuradineolignan, called 4-O-demethylmanassantin A (1) was isolated from underground parts of Saururus chinensis together with three known dineolignans, 4-O-demethylmanassantin B (2), manassantin A (3) and manassantin B (4). | ['Humans', 'Lignans', 'Phytotherapy', 'Plant Extracts', 'Plant Roots', 'Saururaceae'] | 16,859,837 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.140.450'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['A18.400'], ['B01.650.940.800.575.912.250.888']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selenium and immunocompetence in patients with head and neck cancer. | This randomized double-blind placebo-controlled study aimed to determine whether oral intake of 200 microg/d of sodium selenite, a dose within the safe and adequate daily intake (50-200 microg/d) recommended by the U.S. Food and Nutrition Board, will abrogate depressed or enhance normal-level immune functions of patien... | ['Adult', 'Aged', 'Chemical Industry', 'Humans', 'Male', 'Metallurgy', 'Middle Aged', 'Occupational Exposure', 'Petroleum', 'Semen', 'Trace Elements'] | 11,049,203 | [['M01.060.116'], ['M01.060.116.100'], ['J01.576.655.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576.655.875.400'], ['M01.060.116.630'], ['N06.850.460.350.600'], ['D20.345.630', 'N06.230.132.258.630'], ['A12.200.732'], ['D01.268.811', 'D27.505.696.494.555', 'G07.203.300.681.500.555', 'J02.500.681.500.... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Identification and characterization of a centrosomal protein, FOR20 as a novel S100A6 target. | S100A6 is a Ca2+-signal transducer that interacts with numerous proteins and regulates their biochemical functions. Here we identified a centrosomal protein, FOR20 (FOP-related protein of 20 kDa) as a novel S100A6 target by screening protein microarrays carrying 19,676 recombinant GST-fused human proteins. Binding expe... | ['Animals', 'COS Cells', 'Cell Cycle Proteins', 'Cells, Cultured', 'Centrosome', 'Chlorocebus aethiops', 'HeLa Cells', 'Humans', 'Protein Array Analysis', 'Protein Binding', 'Proteins', 'S100 Calcium Binding Protein A6', 'S100 Proteins', 'Substrate Specificity'] | 28,765,046 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D12.776.167'], ['A11.251'], ['A11.284.430.214.190.750.585.160', 'A11.284.430.214.190.750.820.500.500'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.11... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spectral-motion aftereffects and the tritone paradox among Canadian subjects. | The effect of spectral motion on the tritone paradox was investigated by pretesting subjects residing in southwestern Ontario, Canada, on the tritone task, presenting them with a continuous ascending or descending chromatic scale created using Shepard tones, and then retesting them on the tritone task. Results indicate... | ['Adult', 'Attention', 'Cross-Cultural Comparison', 'Female', 'Humans', 'Male', 'Mental Recall', 'Ontario', 'Pitch Discrimination', 'Psychoacoustics', 'Sound Spectrography'] | 9,529,905 | [['M01.060.116'], ['F02.830.104.214'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['Z01.107.567.176.639'], ['F02.463.593.071.700.408', 'G07.888.125.700.408'], ['E01.370.382.375.060.530', 'E01.370.685.628', 'F04.096.753.628'], ['E05.855']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
BioCatNet: A Database System for the Integration of Enzyme Sequences and Biocatalytic Experiments. | The development of novel enzymes for biocatalytic processes requires knowledge on substrate profile and selectivity; this can be derived from databases and from publications. Often, these sources lack time-course data for the substrate or product, and an unambiguous link between experiment and enzyme sequence. The lack... | ['Amino Acid Sequence', 'Biocatalysis', 'Databases, Protein', 'Enzymes', 'Protein Engineering'] | 27,562,499 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['D08.811'], ['E05.393.420.601']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Implementation of technetium-99m MIBI SPECT imaging guidelines: optimizing the two day stress-rest protocol. | OBJECTIVES: In a previous study in 460 patients, we found that in patients with suspected or known coronary artery disease undergoing stress-rest technetium-99m sestamibi (MIBI) SPECT myocardial perfusion imaging, rest SPECT imaging could be withhold in approximately 20% of patients because of a completely normal stres... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Contrast Media', 'Diagnosis, Differential', 'Exercise Test', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Practice Guidelines as Topic', 'Rest', 'Sensitivity and Specificity', 'Technetium Tc 99m Sestamibi', 'Tomography, Emission-Computed, Singl... | 9,306,147 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.259.500', 'D27.720.259'], ['E01.171'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647', 'C14.907.585'], ['N04.761.700.350.650', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Mucociliary activity and histopathology of sinus mucosa in experimental maxillary sinusitis: a comparison of systemic administration of antibiotic and antibiotic delivery by polylactic acid polymer. | To evaluate the efficacy of antibiotic delivered by polyactic acid (PLA) polymer in sinusitis, we induced maxillary sinusitis in 32 New Zealand white rabbits by occluding the sinus ostium and inoculating the sinus cavity with Streptococcus pneumoniae. The rabbits were divided into three groups consisting of group 1 (co... | ['Ampicillin', 'Animals', 'Delayed-Action Preparations', 'Drug Delivery Systems', 'Humans', 'Lactates', 'Lactic Acid', 'Maxillary Sinus', 'Maxillary Sinusitis', 'Mucociliary Clearance', 'Polyesters', 'Polymers', 'Rabbits', 'Treatment Outcome'] | 7,630,296 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['B01.050'], ['D26.255.210', 'E02.319.300.253'], ['E02.319.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['A04.531.621.578'], ['C01.748.749.578', 'C08.460.692.752.578', 'C0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Predictable nitrous oxide uptake enables simple oxygen uptake monitoring during low flow anaesthesia. | The uptake rate of oxygen and nitrous oxide were studied during low flow anaesthesia with enflurane or isoflurane in nitrous oxide with either spontaneous or controlled ventilation. The excess gas flow and composition were analysed. The nitrous oxide uptake rate was in agreement with Severinghaus' formula VN20 1000.t-0... | ['Adult', 'Anesthesia, Inhalation', 'Enflurane', 'Female', 'Humans', 'Isoflurane', 'Male', 'Models, Biological', 'Nitrous Oxide', 'Oxygen Consumption', 'Respiration, Artificial'] | 8,311,207 | [['M01.060.116'], ['E03.155.197.197'], ['D02.355.601.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.355.601.570'], ['E05.599.395'], ['D01.362.635.625', 'D01.625.550.550', 'D01.650.550.587.650'], ['G03.680'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The first anthropological study of the victims of World War I]. | In Italy many hundreds of victims of both armies who fought WWI still attend to be recovered and, if possible, identified and given back to their relatives. This study has as its objective to carry out a correct recovery, anthropological analysis and possible identification of these soldiers. Our plan has been elaborat... | ['Forensic Anthropology', 'Humans', 'Italy', 'Warfare'] | 21,563,388 | [['I01.076.368.400', 'I01.198.780.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['I01.880.735.950.500']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
International migration of health manpower in Sub-Saharan Africa. | This paper concerns itself with a few questions related to the impact of the emigration of health manpower on the health status of individuals and economic development of Sub-Saharan Africa (SSA). The paper evaluates the harmfulness of the migration from Sub-Saharan Africa. The analysis leads to some observations about... | ['Africa', 'Developing Countries', 'Economics', 'Emigration and Immigration', 'Health Status', 'Health Workforce', 'Humans', 'Quality of Health Care'] | 2,237,504 | [['Z01.058'], ['I01.615.500.300'], ['I01.261', 'N03.219'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['N02.350', 'N04.452.525.500', 'N05.300.420.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761', 'N05.715']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Transient hemophagocytosis in Brucella melitensis infection. | Bone marrow phagocytic activity was studied in 40 patients with Brucella melitensis infection and 35 patients with a variety of medical conditions. Evidence of erythrophagocytosis was found in 14 of the 40 patients with B melitensis infection and in 15 of the 35 control cases; this was taken as baseline bone marrow pha... | ['Adult', 'Aged', 'Blood Platelets', 'Bone Marrow', 'Brucellosis', 'Erythrocytes', 'Female', 'Histiocytes', 'Humans', 'Male', 'Middle Aged', 'Phagocytosis', 'Splenomegaly'] | 6,546,508 | [['M01.060.116'], ['M01.060.116.100'], ['A11.118.188', 'A15.145.229.188'], ['A15.382.216'], ['C01.150.252.400.167'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.329.372.385', 'A11.627.482.385', 'A11.733.397.385', 'A15.382.670.522.385', 'A15.382.680.397.385'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chitin from Penaeus merguiensis via microbial fermentation processing and antioxidant activity. | The ability of three proteases producing bacteria such as Pseudomonas aeruginosa, Serratia marcescens, and Bacillus pumilus on the demineralization and deproteinzation efficiency of shrimp waste, for chitin extraction, was investigated. Statistical analysis of data was showed a significant difference between the percen... | ['Animals', 'Antioxidants', 'Chitin', 'Chitosan', 'Fermentation', 'Hydrolysis', 'Penaeidae', 'Spectroscopy, Fourier Transform Infrared'] | 26,519,877 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D05.750.078.139', 'D09.698.211'], ['D05.750.078.139.500', 'D09.698.211.500'], ['G02.111.158.249', 'G03.191.249'], ['G02.380'], ['B01.050.500.131.365.190.660'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Thinking a Lot" Among the Khwe of South Africa: A Key Idiom of Personal and Interpersonal Distress. | "Thinking too much", and variations such as "thinking a lot", are common idioms of distress across the world. The contextual meaning of this idiom of distress in particular localities remains largely unknown. This paper reports on a systematic study of the content and cause, consequences, and social response and coping... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Qualitative Research', 'South Africa', 'Stress, Psychological', 'Thinking'] | 26,487,660 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['H01.770.644.241.850'], ['Z01.058.290.175.735'], ['F01.145.126.990', 'F02.830.900'], ['F02.463.785']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
Nonword Repetition and Vocabulary Knowledge as Predictors of Children's Phonological and Semantic Word Learning. | Purpose: This study examined the unique and shared variance that nonword repetition and vocabulary knowledge contribute to children's ability to learn new words. Multiple measures of word learning were used to assess recall and recognition of phonological and semantic information.Method: Fifty children, with a mean age... | ['Child', 'Child Language', 'Child, Preschool', 'Female', 'Humans', 'Imitative Behavior', 'Language Tests', 'Learning', 'Male', 'Mental Recall', 'Pattern Recognition, Physiological', 'Phonetics', 'Recognition, Psychology', 'Regression Analysis', 'Semantics', 'Speech', 'Vocabulary'] | 28,241,284 | [['M01.060.406'], ['F01.525.200.310.250'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.510'], ['F04.711.513.240'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.425.540.641'], ['F02.463.593.524'], ['L01.559.598.518'], ['F02.463.425.540.706'], ['E05.318.740.750', 'N05.715.360.750.695'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Spiking neuron model for temporal sequence recognition. | A biologically inspired neuronal network that stores and recognizes temporal sequences of symbols is described. Each symbol is represented by excitatory input to distinct groups of neurons (symbol pools). Unambiguous storage of multiple sequences with common subsequences is ensured by partitioning each symbol pool into... | ['Action Potentials', 'Algorithms', 'Brain', 'Computer Simulation', 'Excitatory Postsynaptic Potentials', 'Inhibitory Postsynaptic Potentials', 'Language', 'Mathematical Computing', 'Mathematical Concepts', 'Nerve Net', 'Neural Inhibition', 'Neural Networks, Computer', 'Neural Pathways', 'Neurons', 'Reaction Time', 'Sp... | 19,842,991 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['L01.224.160'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G04.580.887.374', 'G07.265.675.887.374', 'G07.265.755.500', 'G07.265.880.750.400', 'G11... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]'] | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Clinical value of thymidine kinase and tissue polypeptide specific antigen in breast cancer. | Thymidine kinase (TK) and tissue polypeptide specific antigen (TPS) were determined in breast cancer (BC) patients (n = 83), normal healthy women (n = 30) and 18 women with different benign mastopathies. Mean serum levels of TK and TPS in BC patients showed significant increases from their corresponding levels in healt... | ['Biomarkers, Tumor', 'Bone Neoplasms', 'Breast Neoplasms', 'Female', 'Humans', 'Mastectomy, Radical', 'Peptides', 'Postoperative Period', 'Prognosis', 'Tamoxifen', 'Thymidine Kinase', 'Tissue Polypeptide Antigen'] | 8,112,021 | [['D23.101.140'], ['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466.678'], ['D12.644'], ['E04.614.750', 'N02.421.585.753.750'], ['E01.789'], ['D02.455.426.559.389.150.700.900'], ['D08.811.913.696.620.750'], ['D12.644.875', 'D23.050.285.840', '... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Oligonucleotide-based pharmaceuticals: Non-clinical and clinical safety signals and non-clinical testing strategies. | Antisense oligonucleotides, short interfering RNAs (siRNAs) and aptamers are oligonucleotide-based pharmaceuticals with a promising role in targeted therapies. Currently, five oligonucleotide-based pharmaceuticals have achieved marketing authorization in Europe or USA and many more are undergoing clinical testing. Howe... | ['Animals', 'Drug-Related Side Effects and Adverse Reactions', 'Guidelines as Topic', 'Humans', 'Immune System', 'Kidney', 'Liver', 'Mutagenicity Tests', 'Oligonucleotides', 'RNA, Small Interfering', 'Species Specificity', 'Tissue Distribution'] | 28,966,105 | [['B01.050'], ['C25.100'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A15.382'], ['A05.810.453'], ['A03.620'], ['E05.393.560', 'E05.940.560'], ['D13.695.578.424'], ['D13.150.650.700', 'D13.444.735.150.700', 'D13.444.735.790.552.875'], ['G16.824'], ['G03.787.917', 'G07.690.725... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The sulfatase pathway as estrogen supply in endometrial cancer. | OBJECTIVE: Contradictory results are reported about the level of steroid sulfatase (STS), estrogen sulfotransferase (SULT1E1; together, the sulfatase pathway) and aromatase (CYP19A1) in endometrial cancer (EC). The aim of this study was to explore the levels of these enzymes in a well-characterized cohort of EC patient... | ['Aged', 'Aged, 80 and over', 'Aromatase', 'Endometrial Neoplasms', 'Endometrium', 'Estrogens', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'Postmenopause', 'RNA, Messenger', 'Signal Transduction', 'Steryl-Sulfatase', 'Sulfotransferases'] | 30,217,785 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.244.453.489.500', 'D08.244.453.915.099', 'D08.811.682.690.708.170.447.500', 'D08.811.682.690.708.170.915.099', 'D12.776.422.220.453.489.500', 'D12.776.422.220.453.915.099'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['A05.360.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Adjusting to progress: interactions between the National Library of Medicine and health sciences librarians, 1961-2001. | Most health sciences librarians would agree that the National Library of Medicine's (NLM's) leadership and its services have been highly beneficial to the field, but this does not prevent specific NLM actions--or lack of action--from being perceived as annoying or infuriating. Over the past forty years, NLM's interacti... | ['History, 20th Century', 'Information Services', 'Information Storage and Retrieval', 'Librarians', 'Libraries, Medical', 'National Library of Medicine (U.S.)', 'United States'] | 11,838,459 | [['K01.400.504.968'], ['L01.453'], ['L01.313.500.750.280', 'L01.470'], ['M01.526.555'], ['J03.400.596.831.937', 'L01.346.596.719.875'], ['I01.409.418.750.600.650.496.490', 'J03.400.596.831.937.725', 'L01.346.596.719.875.500', 'N03.540.052.750.490', 'N03.540.348.500.500.600.650.496.742'], ['Z01.107.567.875']] | ['Humanities [K]', 'Information Science [L]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Clinical evaluation of the effect of a remineralizing toothpaste on dentinal sensitivity. | Dentinal hypersensitivity is a common dental problem without a satisfactory solution. Most therapies have focused on either trying to block the stimulation of dentinal nerves or on sealing open dentinal tubules. This study evaluated, in a double blind clinical trial, the effect of Enamelon, a dentifrice containing sodi... | ['Analysis of Variance', 'Calcium', 'Calcium Phosphates', 'Chi-Square Distribution', 'Dentifrices', 'Dentin Sensitivity', 'Double-Blind Method', 'Female', 'Fluorides', 'Humans', 'Logistic Models', 'Male', 'Phosphates', 'Statistics, Nonparametric'] | 10,686,861 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D25.376', 'D27.720.269.380... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Rapid pre-tension loss in the Ilizarov external fixator: an in vitro study. | BACKGROUND AND PURPOSE: Wire pre-tension in the Ilizarov frame is considered to be important in order to reduce movements that can impair fracture healing. Wires will eventually lose part of their pre-tension, however. In order to gain more insight into the need for wire pre-tension, we investigated: (1) the amount of ... | ['Biomechanical Phenomena', 'Bone Wires', 'Equipment Failure Analysis', 'External Fixators', 'Ilizarov Technique', 'Materials Testing', 'Stress, Mechanical', 'Tensile Strength'] | 17,966,025 | [['G01.154.090', 'G01.374.089'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['E05.325.192'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['E04.555.120.380', 'E04.555.300.380'], ['E05.570'], ['G01.374.835'], ['G01.374.850']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A fast synaptic potential mediated by NMDA and non-NMDA receptors. | A fast synaptic potential mediated by NMDA and non-NMDA receptors. J. Neurophysiol. 78: 2693-2706, 1997. Excitatory synaptic transmission in the CNS often is mediated by two kinetically distinct glutamate receptor subtypes that frequently are colocalized, the N-methyl--aspartate (NMDA) and non-NMDA receptors. Their syn... | ['2-Amino-5-phosphonovalerate', '6-Cyano-7-nitroquinoxaline-2,3-dione', 'Animals', 'Electric Stimulation', 'Excitatory Amino Acid Antagonists', 'Excitatory Postsynaptic Potentials', 'Goldfish', 'Kainic Acid', 'Ketamine', 'Microelectrodes', 'Neurons', 'Piperazines', 'Pons', 'Receptors, Glutamate', 'Receptors, N-Methyl-D... | 9,356,419 | [['D12.125.070.950.100', 'D12.125.740.025'], ['D03.633.100.857.160'], ['B01.050'], ['E05.723.402'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['B01.050.150.900.493.200.244.248.480'], ['D03.383.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heterogeneity of chicken slow skeletal muscle troponin T mRNA. | The troponin T (TnT) transcripts in chicken slow skeletal muscle were characterized by S1 nuclease mapping and nucleotide sequencing of cDNA produced by RT-PCR and 5'-RACE. We found two kinds of transcripts in the 5'-region, one having the codon for alanine (position 135-137), C (258), and A (262) and the other lacking... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Chickens', 'Chromosome Mapping', 'Cloning, Molecular', 'Molecular Sequence Data', 'Muscle Fibers, Slow-Twitch', 'Muscle, Skeletal', 'Polymerase Chain Reaction', 'RNA, Messenger', 'Single-Strand Specific DNA and RNA Endonucleases', 'Troponin T'] | 10,617,857 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.393.183'], ['E05.393.220'], ['L01.453.245.667'], ['A10.690.552.500.500.700', 'A11.620.249.700'], ['A02.633.567', 'A10.690.552.500'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Protective effect of recombinant TM-N and recombinant soluble RAGE in a mouse model of acute hepatic failure]. | OBJECTIVE: To evaluate the roles of N-terminal lectin-like domain of thrombomodulin (TM-N) and receptor for advanced glycation end products (RAGE) in acute hepatic failure using a mouse model system.METHODS: Acute hepatic failure was induced in Kunming mice by intraperitoneal injection of D-galactosamine (D-Galn at 600... | ['Animals', 'Disease Models, Animal', 'Galactosamine', 'Interleukin-1beta', 'Liver', 'Liver Failure, Acute', 'Mice', 'Mice, Inbred Strains', 'Receptor for Advanced Glycation End Products', 'Receptors, Immunologic', 'Recombinant Proteins', 'Thrombomodulin', 'Tumor Necrosis Factor-alpha'] | 24,331,634 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D09.067.342.356'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.374.500.400.600', 'D23.529.374.465.131.600', 'D23.529.374.500.400.600'], ['A03.620'], ['C06.552.308.500.750'], ['B01.050.150.900.64... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upper body reshaping for the woman with massive weight loss: an algorithmic approach. | BACKGROUND: Body contouring after massive weight loss represents a rather new surgical field. Many areas of the body are affected such as the back, the upper arms, and the breasts in the upper body. Combining more than one such area in a single operative step can yield many advantages. The author proposes a single-step... | ['Adolescent', 'Adult', 'Algorithms', 'Arm', 'Back', 'Breast', 'Dermatologic Surgical Procedures', 'Female', 'Humans', 'Lipectomy', 'Middle Aged', 'Obesity', 'Patient Satisfaction', 'Reconstructive Surgical Procedures', 'Weight Loss'] | 20,361,187 | [['M01.060.057'], ['M01.060.116'], ['G17.035', 'L01.224.050'], ['A01.378.800.075'], ['A01.923.176'], ['A01.236'], ['E04.680.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.530', 'E02.650.500.062.937', 'E04.062.937', 'E04.680.450'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A novel bicomponent hemolysin from Bacillus cereus. | A procedure combining isoelectric focusing (Sephadex IEF) and fast protein liquid chromatography (Superose 12; Mono-Q) removed hemolytic activity (presumably a contaminant) from partially purified preparations of the multicomponent diarrheal enterotoxin produced by Bacillus cereus. However, when the separated fractions... | ['Antibodies, Monoclonal', 'Antigens, Bacterial', 'Bacillus cereus', 'Bacterial Proteins', 'Bacterial Toxins', 'Hemolysin Proteins', 'Hemolytic Plaque Technique', 'Immunoblotting', 'Macromolecular Substances', 'Species Specificity'] | 2,114,359 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.161'], ['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218.252'], ['D12.776.097'], ['D23.946.123'], ['D12.776.543.695.444'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Taste receptor cells arise from local epithelium, not neurogenic ectoderm. | Except for taste bud cells, all sensory receptor cells and neurons have been shown to originate from neurogenic ectoderm (i.e., neural tube, neural crest, or ectodermal placodes). Descriptive studies on taste buds indicate that they, however, may arise from local epithelium. To determine whether taste receptor cells or... | ['Animals', 'Cell Line', 'Crosses, Genetic', 'Ectoderm', 'Epithelium', 'Female', 'Hydroxymethylglutaryl CoA Reductases', 'Male', 'Mice', 'Mice, Transgenic', 'Mosaicism', 'Promoter Regions, Genetic', 'Sex Chromosome Aberrations', 'Taste', 'Taste Buds', 'Tongue', 'X Chromosome', 'beta-Galactosidase'] | 7,892,199 | [['B01.050'], ['A11.251.210'], ['E05.393.281'], ['A16.504.273'], ['A10.272'], ['D08.811.682.047.820.150.415'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['G05.365.590.175.595'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lack of Transmission of Chronic Wasting Disease to Cynomolgus Macaques. | Chronic wasting disease (CWD) is a fatal prion disease that can infect deer, elk, and moose. CWD was first recognized in captive deer kept in wildlife facilities in Colorado from 1967 to 1979. CWD has now been detected in 25 U.S. states, 2 Canadian provinces, South Korea, Norway, and Finland. It is currently unknown if... | ['Animals', 'Biological Assay', 'Deer', 'Disease Models, Animal', 'Female', 'Macaca fascicularis', 'Male', 'Species Specificity', 'Wasting Disease, Chronic'] | 29,695,429 | [['B01.050'], ['E05.091'], ['B01.050.150.900.649.313.500.380.373'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['G16.824'], ['C01.207.800.858', 'C10.228.228.800.858', 'C10.574.843.925', 'C22.955']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors That Influence Breastfeeding Initiation Among African American Women. | OBJECTIVE: To examine cultural and socioenvironmental factors that affect breastfeeding initiation among African American women.DESIGN: Qualitative descriptive design and conventional content analysis.SETTING: A large, inner-city, primary care center affiliated with a 500-bed children's hospital within a large, Northea... | ['Adult', 'African Americans', 'Breast Feeding', 'Cultural Characteristics', 'Environment', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Maternal Behavior', 'Socioeconomic Factors', 'United States'] | 29,550,175 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['F01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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