Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Charter for disabled people using hospitals: a completed access audit cycle. | This completed audit cycle assessed access for disabled people to a district general hospital, in relation to standards laid down in the Royal College of Physicians Charter for Disabled People using Hospitals. The project was effective in demonstrating problems and implementing change to overcome them. It was also usef... | ['Disabled Persons', 'Elevators and Escalators', 'Health Services Accessibility', 'Hospital Design and Construction', 'Hospitals, General', 'Humans', 'London', 'Management Audit', 'Parking Facilities', 'Personnel, Hospital', 'Telephone', 'Toilet Facilities', 'Wheelchairs'] | 10,816,876 | [['M01.150'], ['J01.086.339.115'], ['N04.590.374.350', 'N05.300.430'], ['J01.086.339.250', 'N02.278.200.403'], ['N02.278.421.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.433.553', 'Z01.542.363.300.553'], ['N04.452.500'], ['J03.970.680'], ['M01.526.485.740', 'N02.360.740'], ['L01.178.847.698'], ['J03.96... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
Cyclosporine in pediatric kidney transplantation. | The immunosuppressive treatment with cyclosporin A plus low-dose prednisolone in 33 children after kidney transplantation was compared with conventional treatment with azathioprine plus regular prednisolone dosage in 34 children. The results showed the following: Graft survival in the CyA group is significantly better ... | ['Adolescent', 'Azathioprine', 'Child', 'Child, Preschool', 'Cyclosporins', 'Female', 'Graft Rejection', 'Growth', 'Humans', 'Kidney', 'Kidney Transplantation', 'Male', 'Prednisolone'] | 3,101,430 | [['M01.060.057'], ['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['M01.060.406'], ['M01.060.406.448'], ['D04.345.566.235', 'D12.644.641.235'], ['G12.875.545.328'], ['G07.345.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence of lower urinary tract symptoms in Finnish men: a population-based study. | OBJECTIVE: To determine the prevalence of lower urinary tract symptoms (LUTS) in Finnish men, using a population-based cross-sectional survey.SUBJECTS AND METHODS: In 1994, a modified Danish prostatic symptom score system (DAN-PSS-1) questionnaire on the occurrence and severity of LUTS was mailed to all men (3143) born... | ['Age Factors', 'Aged', 'Cohort Studies', 'Cross-Sectional Studies', 'Finland', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Urban Health', 'Urinary Incontinence', 'Urinary Retention', 'Urination Disorders'] | 9,523,653 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A randomized controlled study of peripheral parenteral nutrition in moderate and severe alcoholic hepatitis. | We performed a controlled trial of peripheral hyperalimentation in moderate and severe alcoholic hepatitis to determine whether improvement in survival and liver function could be obtained. Twelve patients with moderate and 22 with severe alcoholic hepatitis were randomized to 28 days of peripheral parenteral nutrition... | ['Amino Acids', 'Clinical Trials as Topic', 'Hepatitis, Alcoholic', 'Humans', 'Liver Function Tests', 'Parenteral Nutrition, Total', 'Random Allocation'] | 3,142,949 | [['D12.125'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C06.552.380.290', 'C06.552.645.490', 'C25.775.100.087.645.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.372.460'], ['E02.421.505.575', 'E02.642.500.505.750'], ['E05.318.370.700', 'E05.581.500.805', 'N05.71... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The placenta in pseudoxanthoma elasticum: clinical, structural and immunochemical study. | Pseudoxanthoma elasticum (PXE) is a rare genetic disorder clinically characterized by skin, cardiovascular and eye manifestations, mainly due to calcification and fragmentation of elastic fibres. Although infrequent, complications during pregnancy in women affected by PXE have been reported. The aim of the present stud... | ['Adult', 'Calcinosis', 'Chemical Precipitation', 'Female', 'Fibrin', 'Fibronectins', 'Gestational Age', 'Humans', 'Immunohistochemistry', 'Microscopy, Electron', 'Minerals', 'Necrosis', 'Organ Size', 'Placenta', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Pseudoxanthoma Elasticum', 'Vitronectin'] | 11,440,547 | [['M01.060.116'], ['C18.452.174.130'], ['E05.196.150', 'G02.159'], ['D12.776.124.270'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Vulvar plasmablastic lymphoma in a HIV-positive child: a novel extraoral localisation. | Plasmablastic lymphoma (PBL) has been characterised by the World Health Organization as a new entity. This report describes an unusual case of PBL in a 3-year-old HIV-infected patient showing a cutaneous vulvar lesion with 9 months of evolution and prolapsed vulvovaginal mucosa. Histopathological examination of a biops... | ['Child, Preschool', 'Diagnosis, Differential', 'Epstein-Barr Virus Infections', 'Female', 'Humans', 'Lymphoma, AIDS-Related', 'Lymphoma, Large B-Cell, Diffuse', 'Rhabdomyosarcoma', 'Tomography, X-Ray Computed', 'Vulvar Neoplasms'] | 19,561,233 | [['M01.060.406.448'], ['E01.171'], ['C01.925.256.466.313', 'C01.925.928.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480.150.450', 'C15.604.515.569.480.150.450', 'C20.683.515.761.480.150.450'], ['C04.557.386.480.150.585', 'C15.604.515.569.480.150.585', 'C20.683.515.761.480.150.585'], ['C04.557.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neutrophil-to-lymphocyte ratio as a detection marker of tumor recurrence in patients with muscle-invasive bladder cancer after radical cystectomy. | PURPOSE: High-neutrophil to lymphocyte ratio (NLR) values have been shown to be associated with a poor prognosis in many human malignant tumors. We evaluated the correlation of the NLR with other variables in patients with muscle-invasive bladder cancer after radical cystectomy (RC); in particular, we evaluated chronol... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cystectomy', 'Disease-Free Survival', 'Female', 'Humans', 'Lymphocyte Count', 'Lymphocytes', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neutrophils', 'Retrospective Studies', 'Urinary Bladder Neoplasms'] | 27,038,696 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.950.774.150'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Human circadian phase-response curves for exercise. | KEY POINTS: Exercise elicits circadian phase-shifting effects, but additional information is needed. The phase-response curve describing the magnitude and direction of circadian rhythm phase shifts, depending on the time of the zeigeber (time cue) stimulus, is the most fundamental chronobiological tool for alleviating ... | ['Adolescent', 'Adult', 'Aged', 'Circadian Rhythm', 'Exercise', 'Female', 'Humans', 'Light', 'Male', 'Middle Aged', 'Young Adult'] | 30,784,068 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.180.562.190'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Gender differences in substance use treatment entry and retention among prisoners with substance use histories. | OBJECTIVES: We examined gender similarities and differences in the predictors of substance use treatment entry and of the combination of treatment entry and completion.METHODS: The sample consisted of 2219 male and female program participants. Maximum likelihood probit estimation was used to identify background and att... | ['Adult', 'Antisocial Personality Disorder', 'Depression', 'Educational Status', 'Family', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Likelihood Functions', 'Male', 'Men', 'Models, Psychological', 'Motivation', 'Patient Compliance', 'Patient Dropouts', 'Predictive Value of Tests', 'Prisoners', 'Resid... | 15,284,053 | [['M01.060.116'], ['F03.675.050'], ['F01.145.126.350'], ['N01.824.196'], ['F01.829.263', 'I01.880.853.150'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Vasodilator reserve in collateral-dependent myocardium as measured by positron emission tomography. | Myocardial blood flow can be accurately quantitated in patients using positron emission tomography and oxygen-15 labelled water. The purpose of this study was to determine the vasodilator reserve in myocardium completely perfused by intramyocardial collateral blood flow. We hypothesized that altered relative flow reser... | ['Adult', 'Case-Control Studies', 'Collateral Circulation', 'Coronary Circulation', 'Coronary Disease', 'Coronary Vessels', 'Heart', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Tomography, Emission-Computed', 'Vasodilation'] | 8,458,352 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G09.330.100.248'], ['G09.330.100.324'], ['C14.280.647.250', 'C14.907.585.250'], ['A07.015.114.269', 'A07.015.908.194'], ['A07.541'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Defensive practice in mental health. | AIM: This study aimed to assess the extent of defensive clinical practice by psychiatrists and psychiatric nurses in a New Zealand Mental Health Service.METHOD: An anonymous questionnaire survey, addressing perceptions of a variety of defensive practices, was sent to all psychiatrists and psychiatric nurses working in ... | ['Defensive Medicine', 'Health Care Surveys', 'Humans', 'Mental Health Services', 'New Zealand', 'Psychiatric Nursing', 'Psychiatry'] | 19,098,951 | [['I01.880.604.583.524.300', 'N03.706.535.606.300'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.408', 'N02.421.461'], ['Z01.639.760.747', 'Z01.678.100.747'], ['H02.478.676.710', 'N02.421.533.778'... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Structure-activity relationships in the interactions of alkoxymethylenedioxybenzene derivatives with rat hepatic microsomal mixed-function oxidases in vivo. | Following in vivo administration to rats of equimolar amounts of a series of 4-n-alkoxymethylenedioxybenzene (AMDB) derivatives, hepatic microsomal aryl hydrocarbon hydroxylase (AHH) activities, total cytochrome P-450 levels, and AMDB metabolite-cytochrome P-450 spectral complex (455 nm) formation were well correlated ... | ['Animals', 'Aryl Hydrocarbon Hydroxylases', 'Cytochrome P-450 Enzyme System', 'Dioxolanes', 'Dioxoles', 'Male', 'Microsomes, Liver', 'Mixed Function Oxygenases', 'Oxidoreductases', 'Protein Binding', 'Rats', 'Rats, Inbred Strains', 'Spectrophotometry', 'Structure-Activity Relationship'] | 6,865,922 | [['B01.050'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D03.383.246.238'], ['D03.383.246'], ['A11.284.835.540.541'], ['D08.811.682.690.708'], ['D08.811.682'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On-line measurement of nitric oxide release from organic nitrates in the intact coronary circulation. | This study determines the release of nitric oxide (NO) from the coronary circulation of Langendorff hearts of rabbits, subsequent to administration of glyceryl trinitrate (GTN) and SIN-1. NO was measured on-line in the coronary effluent by the oxyhaemoglobin technique. Infusion of either GTN (10-40 mumoles/l) or SIN-1 ... | ['Animals', 'Arginine', 'Bradykinin', 'Coronary Vessels', 'In Vitro Techniques', 'Molsidomine', 'Nitric Oxide', 'Nitroglycerin', 'Oxyhemoglobins', 'Rabbits', 'Substance P', 'Trypsin', 'Vasodilation', 'omega-N-Methylarginine'] | 1,719,435 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['A07.015.114.269', 'A07.015.908.194'], ['E05.481'], ['D03.383.129.462.580.693.450', 'D03.383.53... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Statistical optimization for cadmium removal using Ulva fasciata biomass: Characterization, immobilization and application for almost-complete cadmium removal from aqueous solutions. | Cadmium is a global heavy metal pollutant. Marine green algae were used as efficient, low cost and eco-friendly biosorbent for cadmium ions removal from aqueous solutions. Plackett-Burman design was applied to determine the most significant factors for maximum cadmium removal from aqueous solutions using dry Ulva fasci... | ['Biomass', 'Cadmium', 'Chlorophyta', 'Kinetics', 'Solutions', 'Ulva', 'Waste Disposal, Fluid', 'Water', 'Water Pollutants, Chemical', 'Water Purification'] | 30,127,459 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['B01.650.940.150'], ['G01.374.661', 'G02.111.490'], ['D26.776'], ['B01.650.940.150.900'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.9... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Circulating regulatory B cell subsets in patients with neuromyelitis optica spectrum disorders. | This study analyzed the populations of three different subsets of regulatory B cells (Bregs) in the peripheral blood mononuclear cells (PBMCs) of patients with neuromyelitis optica spectrum disorders (NMOSDs) and explored the relationship between the changes in these subsets of Bregs and the severity of NMOSD. A total ... | ['Adult', 'Aged', 'Antigens, CD', 'B-Lymphocytes, Regulatory', 'Female', 'Flow Cytometry', 'Humans', 'Male', 'Middle Aged', 'Neuromyelitis Optica'] | 28,389,940 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.063.438.450.300', 'A11.118.637.555.567.550.450.300', 'A11.118.637.555.567.562.200.300', 'A15.145.229.637.555.567.550.450.300', 'A15.145.229.637.555.567.562.200.300', 'A15.382.032.438.450.300', 'A15.382.490.555.567.562.450.300'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Is there increased sympathetic activity in patients with hypertrophic cardiomyopathy? | OBJECTIVES: This study aimed to assess autonomic nervous system activity in patients with hypertrophic cardiomyopathy.BACKGROUND: Patients with hypertrophic cardiomyopathy are traditionally thought to have increased sympathetic activity. However, convincing evidence is lacking.METHODS: Heart rate variability was assess... | ['Adolescent', 'Adult', 'Amiodarone', 'Cardiomyopathy, Hypertrophic', 'Case-Control Studies', 'Circadian Rhythm', 'Death, Sudden, Cardiac', 'Electrocardiography, Ambulatory', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged'] | 7,608,453 | [['M01.060.057'], ['M01.060.116'], ['D03.633.100.127.075'], ['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.180.562.190'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Negative priming in same-different matching: further evidence for a central locus of inhibition. | Responses to recently ignored information may be slower or less accurate than responses to information not recently encountered. Such negative priming effects imply that the mechanism of selective attention operates on unattended, as well as attended, information. In the present experiment, subjects judged the second a... | ['Adult', 'Attention', 'Discrimination Learning', 'Humans', 'Mental Recall', 'Pattern Recognition, Visual', 'Psychomotor Performance', 'Reaction Time', 'Reading'] | 2,243,764 | [['M01.060.116'], ['F02.830.104.214'], ['F02.463.425.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['L01.559.423.557']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Identification of Critical Paraoxonase 1 Residues Involved in High Density Lipoprotein Interaction. | Paraoxonase 1 (PON1) is a high density lipoprotein (HDL)-associated protein with atherosclerosis-protective and systemic anti-oxidant functions. We recently showed that PON1, myeloperoxidase, and HDL bind to one another in vivo forming a functional ternary complex (Huang, Y., Wu, Z., Riwanto, M., Gao, S., Levison, B. S... | ['Amino Acid Motifs', 'Apolipoprotein A-I', 'Aryldialkylphosphatase', 'Catalysis', 'Crystallography, X-Ray', 'Humans', 'Lipoproteins, HDL', 'Mutagenesis, Site-Directed', 'Protein Binding'] | 26,567,339 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['D08.811.277.352.660.500'], ['G02.130'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.432', 'D12.776.521.479'], ['E05.393.420.601.575'],... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antioxidant enzyme activities and oxidative stress in human breast cancer. | We have analysed products of lipid peroxidation reactions and activities of antioxidant enzymes in cancerous breast tissue and in corresponding reference tissue. In addition, the serum lipid peroxidation and peroxyl-radical-trapping capacity of breast cancer patients were compared to those of healthy subjects. A total ... | ['Antioxidants', 'Breast Neoplasms', 'Catalase', 'Female', 'Glutathione Peroxidase', 'Glutathione Transferase', 'Humans', 'Lipid Peroxidation', 'Middle Aged', 'Oxidation-Reduction', 'Superoxide Dismutase'] | 8,138,563 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C04.588.180', 'C17.800.090.500'], ['D08.811.682.732.332'], ['D08.811.682.732.500'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.515', 'G03.295.531.587'], ['M01.060.116.630'], ['G02.700', 'G03.295.531'], ['D08.811.6... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The impact of carnitine on serum ammonia concentration and lipid metabolism in patients with alcoholic liver cirrhosis]. | UNLABELLED: Treatment of patients with liver cirrhosis with the signs of liver insufficiency is complex and seldom satisfactory. Carnitine, taking part in liver lipid metabolism might be a potentially effective drug.THE AIM: Of the study was to evaluate the influence of L-carnitine on serum ammonia, cholesterol and tri... | ['Adult', 'Aged', 'Ammonia', 'Carnitine', 'Cholesterol', 'Female', 'Humans', 'Liver Cirrhosis, Alcoholic', 'Male', 'Middle Aged', 'Triglycerides'] | 14,593,957 | [['M01.060.116'], ['M01.060.116.100'], ['D01.362.075', 'D01.625.050'], ['D02.092.877.883.099'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630.380', 'C06.552.645.590', 'C23.550.355.412.380', 'C25.775.100.087.645.550'], ['M01.060.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Contamination profiles of perfluoroalkyl substances in five typical rivers of the Pearl River Delta region, South China. | A survey on contamination profiles of eighteen perfluoroalkyl substances (PFASs) was performed via high performance liquid chromatography-tandem mass spectrometry for surface water and sediments from five typical rivers of the Pearl River Delta region, South China in summer and winter in 2012. The total concentrations ... | ['Alkanesulfonic Acids', 'Caprylates', 'China', 'Environmental Monitoring', 'Fluorocarbons', 'Geologic Sediments', 'Rivers', 'Water Pollutants, Chemical'] | 25,113,179 | [['D02.455.326.146.100', 'D02.886.645.600.055'], ['D02.241.081.222', 'D10.251.122'], ['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.455.526.510.435'], ['G01.311.330', 'G16.500.320'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Metabolic conditions determining the composition and catalytic activity of cytochrome P-450 monooxygenases in Candida tropicalis. | In the microsomal fraction of Candida tropicalis cells, two distinct monooxygenases were detected, depending on the growth conditions. The distinction of the two monooxygenases was evident from: (i) the absorption maxima in the reduced CO difference spectra of the terminal oxidases (cytochromes P-450 and P-448); (ii) t... | ['Alkanes', 'Candida', 'Catalysis', 'Culture Media', 'Cytochrome P-450 Enzyme System', 'Cytochromes', 'Glucose', 'Microsomes', 'Oxygenases'] | 6,690,424 | [['D02.455.326.146'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['G02.130'], ['D27.720.470.305', 'E07.206'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D08.244', 'D12.776.422.220'], ['D09.947.875.359.448'], ['A11.284.835.540'], ['D08.811.682.690']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular cloning and characterization of oocyte-specific Pat1a in Rana rugosa frogs. | The Pat1 gene is expressed in the immature oocytes of Xenopus, and is reportedly involved in regulating the translation of maternal mRNAs required for oocyte-maturation. However, it is still unknown when Pat1a first appears in the differentiating ovary of amphibians. To address this issue, we isolated the full-length P... | ['Animals', 'Cloning, Molecular', 'DNA, Complementary', 'Female', 'Gene Expression', 'Larva', 'Male', 'Oocytes', 'Ovary', 'Ranidae', 'Sex Determination Processes', 'Testosterone', 'Transcription Factors'] | 26,136,381 | [['B01.050'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.297'], ['B05.500.500', 'G07.345.500.550.500.500'], ['A05.360.490.690.680', 'A11.497.497.600'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['B01.050.150.900.090.180.708'], ['G05.813', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interdependence between the aerobic degradation of BPA and readily biodegradable substrates by activated sludge in semi-continuous reactors. | The objective of the present work was to analyze the interrelationship between the aerobic degradation of BPA and readily biodegradable substrates by activated sludge (AS) in semi-continuous reactors (SCRs). AS were obtained from three SCRs fed with glucose, acetate or peptone. AS from these reactors were used as inocu... | ['Acclimatization', 'Aerobiosis', 'Benzhydryl Compounds', 'Biodegradation, Environmental', 'Bioreactors', 'Carbon', 'Organic Chemicals', 'Oxygen Consumption', 'Phenols', 'Sewage', 'Substrate Specificity'] | 30,242,540 | [['G07.025.133', 'G16.012.500.133'], ['G02.111.017', 'G03.049'], ['D02.455.426.559.389.115'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.115', 'J01.897.120.115'], ['D01.268.150'], ['D02'], ['G03.680'], ['D02.455.426.559.389.657'], ['D20.944.932.500'], ['G02.111.835']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
á-Tubulin Acetyltransferase Is a Novel Target Mediating Neurite Growth Inhibitory Effects of Chondroitin Sulfate Proteoglycans and Myelin-Associated Glycoprotein. | Damage to the CNS results in neuronal and axonal degeneration, and subsequent neurological dysfunction. Endogenous repair in the CNS is impeded by inhibitory chemical and physical barriers, such as chondroitin sulfate proteoglycans (CSPGs) and myelin-associated glycoprotein (MAG), which prevent axon regeneration. Previ... | ['Acetyltransferases', 'Animals', 'Chondroitin Sulfate Proteoglycans', 'Down-Regulation', 'Female', 'Histone Deacetylase 6', 'Mice', 'Microtubule Proteins', 'Myelin-Associated Glycoprotein', 'Nerve Regeneration', 'Neurites', 'Neuronal Outgrowth', 'Signal Transduction', 'Tubulin', 'rho-Associated Kinases'] | 29,497,702 | [['D08.811.913.050.134'], ['B01.050'], ['D09.698.735.200', 'D12.776.395.650.750'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D08.811.277.087.520.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['D05.750.078.734', 'D12.776.220.600'], ['D12.776.395.550.570', 'D12.776.503.921.049', 'D12.776.543.550.555', 'D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of diuretics (diacarb and lasix) on the experimental antitumor activity, toxicity and pharmacokinetics of the antibiotic, olivomycin]. | Diacarb or lasix in combination with olivomycin increased the antibiotic antiblastomic activity and toxicity when used for the course treatment of mice with transplanted lymphosarcoma LIO-I. The chemotherapeutic indices of such combinations did not differ from those of olivomycin used alone. Diacarb decreased excretion... | ['Acetazolamide', 'Animals', 'Diuresis', 'Drug Combinations', 'Drug Evaluation, Preclinical', 'Drug Interactions', 'Female', 'Furosemide', 'Kinetics', 'Lymphoma, Non-Hodgkin', 'Male', 'Mice', 'Neoplasms, Experimental', 'Olivomycins', 'Rats'] | 581,050 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['B01.050'], ['G08.852.179'], ['D26.310'], ['E05.290.750', 'E05.337.550'], ['G07.690.773.968'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['G01.374.661', 'G02.111.490'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beyond the mental pain: A case-control study on the contribution of schizoid personality disorder symptoms to medically serious suicide attempts. | BACKGROUND: Clinical and research findings have highlighted the role of interpersonal factors in suicidal behavior with high levels of intent and lethality. Schizoid personality disorder (SPD) is at the extreme end of interpersonal difficulties. Thus, we aimed to understand the contribution of SPD symptoms to suicide b... | ['Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Cross-Sectional Studies', 'Female', 'Humans', 'Intention', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Schizoid Personality Disorder', 'Suicidal Ideation', 'Suicide, Attempted'] | 30,852,349 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['M01.060.116.630... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Pathways of cadmium influx in mammalian neurons. | The influx of the toxic cation Cd2+ was studied in fura 2-loaded rat cerebellar granule neurons. In cells depolarized with Ca2(+)-free, high-KCI solutions, the fluorescence emission ratio (R) increased in the presence of 100 microM Cd2(+). This increase was fully reversed by the Cd2+ chelator tetrakis(2-pyridylmethyl)e... | ['Animals', 'Cadmium', 'Calcium Channel Blockers', 'Cells, Cultured', 'Cytosol', 'Fluorescent Dyes', 'Fura-2', 'Glutamic Acid', 'Models, Neurological', 'Neurons', 'Osmolar Concentration', 'Rats', 'Rats, Sprague-Dawley'] | 10,217,297 | [['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['A11.251'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D03.383.129.462.285', 'D03.633.100.127.250... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Saccharides and temperature dual-responsive hydrogel layers for harvesting cell sheets. | Saccharides and temperature dual-responsive hydrogels have been prepared based on PNIPAAm copolymers containing phenylboronic acid (PBA) groups and used for harvesting cell sheets. The cell sheet could be released from the hydrogel layer at 37 °C simply by increasing sugar concentration, and could be more efficiently r... | ['Acrylic Resins', 'Animals', 'Boronic Acids', 'Carbohydrates', 'Cell Adhesion', 'Cell Culture Techniques', 'Cell Line', 'Hydrogels', 'Mice', 'Temperature'] | 25,415,610 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['B01.050'], ['D01.029.260.110', 'D01.132.285', 'D02.203.200'], ['D09'], ['G04.022'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210'], ['D20.280.320.375', 'D26.255.165.320.375'], ['B01.050.150.9... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Molecular characterization of a German variant of glucose-6-phosphate dehydrogenase deficiency (G6PD Aachen). | Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-chromosome-linked hereditary disorder. Clinically, patients with G6PD deficiency often present with drug- or food-induced hemolytic crises or neonatal jaundice. G6PD is involved in the generation of NADPH and reduced glutathione. In contrast to American, Medit... | ['Adult', 'Aged', 'Amino Acid Substitution', 'Binding Sites', 'DNA Mutational Analysis', 'Dimerization', 'Genetic Variation', 'Germany', 'Glucosephosphate Dehydrogenase', 'Glucosephosphate Dehydrogenase Deficiency', 'Humans', 'Kinetics', 'Male', 'Point Mutation'] | 10,772,881 | [['M01.060.116'], ['M01.060.116.100'], ['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.120'], ['E05.393.760.700.300'], ['G02.206', 'G03.230'], ['G05.365'], ['Z01.542.315'], ['D08.811.682.047.150.300'], ['C15.378.071.141.150.480', 'C16.320.070.480', 'C16.320.565.202.402', 'C18.452.648.202.402'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Positioning of vagal nerve stimulators: technical note. | BACKGROUND: Vagal nerve stimulation has become an important treatment for patients with intractable seizure disorders. Many of these patients will require magnetic resonance imaging (MRIs) of the brain after the stimulator has been implanted to monitor underlying neurologic conditions. Functional MRI (fMRI) is also bei... | ['Electric Stimulation Therapy', 'Electrodes, Implanted', 'Electromagnetic Fields', 'Epilepsy', 'Humans', 'Magnetic Resonance Imaging', 'Vagus Nerve'] | 10,713,198 | [['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E07.305.250.319', 'E07.695.202'], ['G01.358.500.260', 'G01.358.750.500'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.800.050.050.925', 'A08.800.050.600.825', 'A08.800.800.060.920', 'A08.800.800.120.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor. | Interleukin 1 alpha (IL-1 alpha), tumor necrosis factor alpha (TNF alpha), granulocyte-colony-stimulating factor (G-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF) are molecularly distinct cytokines acting on separate receptors. The release of these cytokines can be concomitantly induced by the same... | ['Animals', 'Colony-Stimulating Factors', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Gamma Rays', 'Granulocyte Colony-Stimulating Factor', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Growth Substances', 'Humans', 'Interleukin-1', 'Mice', 'Mice, Inbred Strains', 'Radiation Injuries, Experimental', '... | 2,447,166 | [['B01.050'], ['D12.644.276.374.410.240', 'D12.776.395.240', 'D12.776.467.374.410.240', 'D23.529.374.410.240'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968.477'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200', 'D12.776.467.374.410.240.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Loneliness and pregnancy in an urban Latino community: associations with maternal age and unscheduled hospital utilization. | The objective is to compare loneliness in a pregnant population to a non-pregnant control group, and to evaluate loneliness and unscheduled hospital visits during pregnancy. A prospective cohort study in a Latino urban community including 53 consecutive pregnant women in their first trimester, and 61 non-pregnant women... | ['Adult', 'Appointments and Schedules', 'California', 'Case-Control Studies', 'Female', 'Hispanic Americans', 'Hospitalization', 'Hospitals', 'Humans', 'Loneliness', 'Maternal Age', 'Maternal-Child Health Centers', 'Pregnancy', 'Pregnancy Complications', 'Pregnant Women', 'Urban Population'] | 15,715,019 | [['M01.060.116'], ['N04.452.095'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.686.754.441'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.713', 'I01.880.85... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Long-term results of Charnley low-friction arthroplasty of the hip. | The long-term results of 73 Charnley low-friction arthroplasties with follow-up of 10-14 years are presented. Eight hips required revision for socket migration resulting from excessive medialisation of the cup (2, 2.7%); breakage of the femoral stem (5, 6.8%); and loosening (1). A further 5 hips had radiological change... | ['Adult', 'Age Factors', 'Aged', 'Evaluation Studies as Topic', 'Female', 'Follow-Up Studies', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Reoperation'] | 3,340,930 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.337', 'N05.715.360.335'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.690']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Involvement of a novel ABC transporter and monoalkyl phthalate ester hydrolase in phthalate ester catabolism by Rhodococcus jostii RHA1. | Phthalate esters (PEs) are important environmental pollutants. While the biodegradation of the parent compound, phthalate (PTH), is well characterized, the biodegradation of PEs is not well understood. In particular, prior to this study, genes involved in the uptake and hydrolysis of these compounds were not conclusive... | ['ATP-Binding Cassette Transporters', 'Carboxylic Ester Hydrolases', 'Environmental Pollutants', 'Escherichia coli', 'Esters', 'Gene Deletion', 'Gene Expression', 'Genes, Bacterial', 'Phthalic Acids', 'Rhodococcus'] | 20,038,686 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D08.811.277.352.100'], ['D27.888.284'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.241.400'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.297'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exogenous lipid pneumonia: a retrospective multicentre study of 44 cases in France. | A nationwide retrospective study of exogenous lipid pneumonia (ELP) was carried out to update the data on this disease, with emphasis on thoracic computed tomography (CT) scan and bronchoalveolar lavage (BAL) findings. The inclusion criteria were: 1) presence of abnormal imaging features compatible with the diagnosis o... | ['Bronchoalveolar Lavage Fluid', 'Bronchoscopy', 'Female', 'France', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Occupational Diseases', 'Oils', 'Paraffin', 'Pneumonia, Lipid', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 8,836,660 | [['E05.927.100.500'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ['C24'], ['D10.627'], ['D02.455.612'], ['C01.748.610.529.612', 'C08.381.677.529.612', 'C08.730.610.529.612'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The discovery of addiction. Changing conceptions of habitual drunkenness in America. | The modern conception of alcoholism as a progressive, addictive disease dates from the late 18th century. By the mid-1800s it had become an integral part of American Temperance thought, as did the belief that total abstinence offered the only remedy for intemperance. | ['Alcoholic Intoxication', 'Alcoholism', 'Attitude to Health', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Religion and Psychology', 'Substance-Related Disorders', 'Temperance', 'United States'] | 344,994 | [['C25.775.100.175', 'F03.900.100.300'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.100.150', 'N05.300.150'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.880', 'K01.844.664'], ['C25.775', 'F03.900'], ['F01.914'], ['Z01.107.567.875']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Urine catecholamine excretion after large doses of fentanyl, fentanyl and diazepam and fentanyl, diazepam and pancuronium. | The effects of fentanyl (0.5 mg/kg iv), fentanyl with diazepam (1 mg/kg iv) and fentanyl, diazepam and pancuronium (0.1 mg/kg iv) on heart rate (HR), mean arterial blood pressure (BP), cardiac output (QT), urine flow rate and urine epinephrine and norepinephrine excretion were determined in nine dogs. Fentanyl did not ... | ['Animals', 'Blood Pressure', 'Cardiac Output', 'Catecholamines', 'Diazepam', 'Diuresis', 'Dogs', 'Drug Interactions', 'Epinephrine', 'Fentanyl', 'Heart Rate', 'Norepinephrine', 'Pancuronium', 'Time Factors'] | 871,940 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.150', 'G09.330.380.124'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['D03.633.100.079.080.070.216'], ['G08.852.179'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.968'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Deciphering modifications in swine cardiac troponin I by top-down high-resolution tandem mass spectrometry. | Cardiac troponin I (cTnI) is an important regulatory protein in cardiac muscle, and its modification represents a key mechanism in the regulation of cardiac muscle contraction and relaxation. cTnI is often referred to as the "gold-standard" serum biomarker for diagnosing patients with acute cardiac injury since it is u... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Molecular Sequence Data', 'Myocardium', 'Myocytes, Cardiac', 'Phosphorylation', 'Proteomics', 'Sequence Alignment', 'Swine', 'Tandem Mass Spectrometry', 'Troponin I'] | 20,223,681 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['L01.453.245.667'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.500'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['H01.158.201.843', 'H01.158.273.180.350.700', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Prognostic factors in patients with invasive differentiated thyroid carcinoma who underwent palliative resection]. | In order to determine surgical strategy for locally advanced thyroid carcinoma, a multivariate analysis of prognostic factors was carried out with 70 patients of locally advanced thyroid carcinoma who underwent palliative surgery. Multivariate analysis was conducted by Cox's proportional hazard model. The patients have... | ['Adenocarcinoma', 'Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Carcinoma, Papillary', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Palliative Care', 'Prognosis', 'Proportional Hazards Models', 'Survival Rate', 'Thyroid Neoplasms', 'Thyroidect... | 1,280,319 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Primary aldosteronism. Diagnostic aspects and treatment]. | Despite the relatively low frequency of primary aldosteronism, its diagnosis is of great importance because surgical treatment results, in the majority of cases, in the disappearance of arterial hypertension. We present in this paper six cases with this type of secondary hypertension. The disease was suspected by the c... | ['Adenoma', 'Adrenal Gland Neoplasms', 'Adult', 'Female', 'Humans', 'Hyperaldosteronism', 'Hypertension', 'Hypokalemia', 'Male', 'Middle Aged', 'Sodium Chloride', 'Spironolactone'] | 7,247,580 | [['C04.557.470.035'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.053.800.604'], ['C14.907.489'], ['C18.452.950.565'], ['M01.060.116.630'], ['D01.210.450.150.875', 'D01.857.650'], ['D02.540.679', 'D04.210.500.745.745.855']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Magnetic nanoparticle imaging by random and maximum length sequences of inhomogeneous activation fields. | Biomedical applications of magnetic nanoparticles require a precise knowledge of their biodistribution. From multi-channel magnetorelaxometry measurements, this distribution can be determined by means of inverse methods. It was recently shown that the combination of sequential inhomogeneous excitation fields in these m... | ['Animals', 'Computer Simulation', 'Magnetic Fields', 'Magnetite Nanoparticles', 'Tissue Distribution'] | 24,110,423 | [['B01.050'], ['L01.224.160'], ['G01.358.750'], ['J01.637.512.600.500.144.500'], ['G03.787.917', 'G07.690.725.949']] | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Adrenal steroid regulation of neurotrophic factor expression in the rat hippocampus. | Adrenal steroids and neurotrophic factors are important modulators of neuronal plasticity, function, and survival in the rat hippocampus. Adrenal steroids act through two receptor subtypes, the glucocorticoid receptor (GR) and the mineralocorticoid receptor, and activation of each receptor subtype has distinct biochemi... | ['Adrenalectomy', 'Aldosterone', 'Androstanols', 'Animals', 'Brain-Derived Neurotrophic Factor', 'Corticosterone', 'Fibroblast Growth Factor 2', 'GAP-43 Protein', 'Hippocampus', 'Male', 'Nerve Growth Factors', 'Neurotrophin 3', 'Rats', 'Rats, Sprague-Dawley'] | 9,645,683 | [['E04.270.115'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D04.210.500.054.040'], ['B01.050'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.52... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modified Alderman-Grant resonator with high-power stability for proton electron double resonance imaging. | Proton-electron double resonance imaging (PEDRI) requires a dual EPR/NMR resonator. In order to saturate electron spins, long high-power RF EPR pulses are needed. Dissipated power causes resonator and sample heating, resulting in instability of the resonator frequency and coupling, which in turn causes a reduction in s... | ['Computer-Aided Design', 'Electron Spin Resonance Spectroscopy', 'Equipment Design', 'Equipment Failure Analysis', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Magnetic Resonance Spectroscopy', 'Protons', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Transducers'] | 16,902,975 | [['L01.224.108.150', 'L01.296.110.150'], ['E05.196.867.519.274'], ['E05.320'], ['E05.325.192'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'], ['E05.196.867.519'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling. | Individuals with Down syndrome (DS) are predisposed to develop acute megakaryoblastic leukemia (AMKL), characterized by expression of truncated GATA1 transcription factor protein (GATA1s) due to somatic mutation. The treatment outcome for DS-AMKL is more favorable than for AMKL in non-DS patients. To gain insight into ... | ['Chromosomes, Human, Pair 21', 'Core Binding Factor Alpha 2 Subunit', 'Down Syndrome', 'GATA1 Transcription Factor', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Leukemia, Megakaryoblastic, Acute', 'Multigene Family', 'Phenotype', 'Transcription Factors'] | 16,492,768 | [['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['D12.776.930.155.200.200'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['D12.776.260.235.500', 'D12.776.260.257.100', 'D12.776.930.216.500', 'D12.776.930.314.100'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.90... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Observation of the changes in the locomotor apparatus and calcium-phosphorus metabolism in kidney transplant patients]. | Renal function indices were analyzed as well as those of calcium-phosphorus metabolism and the state of bone skeleton in seven patients with renal transplantation. Consideration is given to a grave complication resulting from a long-term treatment with corticosteroids--aseptic osteonecrosis, found in two of the subject... | ['Adult', 'Azathioprine', 'Bone and Bones', 'Calcium', 'Female', 'Humans', 'Kidney', 'Kidney Diseases', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Phosphorus', 'Postoperative Care', 'Prednisolone', 'Radiography', 'Time Factors'] | 335,661 | [['M01.060.116'], ['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419', 'C13.351.968.419'], ['E02.870.500', 'E04.936.450.485', 'E04.950.77... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Schizophrenia and multiple sclerosis. | A case of multiple sclerosis was diagnosed as paranoid schizophrenia 10 years earlier. The schizophrenic disorder, severe and almost nonremittent for 10 years, failed to respond to adequate drug therapy. The computerized axial tomography scan revealed moderate atrophy of the anterior cerebellar vermis, a finding of int... | ['Adult', 'Cerebellum', 'Diagnosis, Differential', 'Female', 'Humans', 'Multiple Sclerosis', 'Schizophrenia, Paranoid', 'Tomography, X-Ray Computed'] | 6,854,297 | [['M01.060.116'], ['A08.186.211.132.810.428.200'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['F03.700.750.600'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.8... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Coding guidelines for ICD-9 section on mental disorders and reliability of chart clinical diagnoses. | A major innovation of the ICD-10 draft is provision of diagnostic guidelines. This is assumed to be appropriate for use in clinical situations. In Norway a similar approach was adopted when ICD-9 was introduced as the official classification system in 1987. This was done in order to avoid national diagnostic bias and i... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bipolar Disorder', 'Humans', 'Mental Disorders', 'Middle Aged', 'Norway', 'Schizophrenia'] | 2,330,831 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.084.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['Z01.542.816.374'], ['F03.700.750']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The treatment of late post-traumatic orbital deformities. | Trauma to the orbital region may result in fractures of the bony orbit, displacement of which gives rise to malposition of the eye and diplopia. If initial treatment is not feasible or is unsuccessful, later correction may be achieved by osteotomy or reduction and stabilisation of the bony fragments, often with bone gr... | ['Adult', 'Child', 'Female', 'Humans', 'Male', 'Orbital Fractures', 'Skull Fractures', 'Surgery, Plastic', 'Time Factors'] | 3,375,902 | [['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.900.300.284.500.550', 'C26.404.750.684', 'C26.915.300.425.500.550'], ['C10.900.300.918', 'C26.404.750', 'C26.915.300.745'], ['H02.403.810.788'], ['G01.910.857']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Tailoring the atomic structure of graphene nanoribbons by scanning tunnelling microscope lithography. | The practical realization of nanoscale electronics faces two major challenges: the precise engineering of the building blocks and their assembly into functional circuits. In spite of the exceptional electronic properties of carbon nanotubes, only basic demonstration devices have been realized that require time-consumin... | ['Carbon', 'Crystallization', 'Macromolecular Substances', 'Materials Testing', 'Microscopy, Scanning Tunneling', 'Molecular Conformation', 'Nanotechnology', 'Nanotubes', 'Particle Size', 'Photography', 'Surface Properties'] | 18,654,562 | [['D01.268.150'], ['E05.196.300', 'G02.171'], ['D05'], ['E05.570'], ['E01.370.350.515.666.500', 'E05.595.666.500'], ['G02.111.570.820'], ['H01.603', 'J01.897.520.600'], ['J01.637.512.850'], ['G02.712'], ['E01.370.350.600', 'E05.712'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Ev 2, a genetic locus containing structural genes for endogenous virus, codes for Rous-associated virus type 0 produced by line 72 chickens. | ev 2 is one of seven recently described genetic loci of chickens which contain structural genes for endogenous virus. ev 2 is present exclusively in line 72 chickens, an inbred strain of white Leghorns which is homozygous for the capacity to produce Rous-associated virus type 0 (RAV-0), a subgroup E virus. This phenoty... | ['Alleles', 'Animals', 'Avian Leukosis Virus', 'Chick Embryo', 'Chickens', 'Chromosome Mapping', 'Crosses, Genetic', 'Culture Techniques', 'DNA', 'DNA, Viral', 'Female', 'Genes', 'Genes, Viral', 'Male', 'Virus Replication'] | 6,245,230 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A muscular fatigue index based on the relationships between superimposed M wave and preceding background activity. | A practical muscle fatigue index is studied in this paper using the correlation between the instantaneous frequencies (IF's) of the superimposed M wave and the mean power frequency (MPF) of the preceding background activity. A superimposed M wave is an M wave elicited during a sustained contraction and was recently int... | ['Adult', 'Electromyography', 'Exercise', 'Fuzzy Logic', 'Humans', 'Male', 'Muscle Contraction', 'Muscle Fatigue', 'Reference Values'] | 9,775,533 | [['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['G11.427.410.698.277', 'I03.350'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494'], ['G11.427.550'], ['E05.978.810']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Radical cystectomy using endoscopic stapling devices: preliminary experience with a simple and reliable technique. | PURPOSE: We introduce a new technique to decrease operative time and blood loss during radical cystectomy.MATERIALS AND METHODS: We used endoscopic stapling devices for secure hemostasis, as well as rapid division of the bladder and prostatic lateral ligaments, and the deep dorsal vein complex during radical cystectomy... | ['Blood Loss, Surgical', 'Cystectomy', 'Cystoscopy', 'Endoscopy', 'Female', 'Humans', 'Male', 'Surgical Staplers', 'Urinary Bladder Neoplasms'] | 8,976,267 | [['C23.550.414.300', 'C23.550.505.300'], ['E04.950.774.150'], ['E01.370.388.250.180', 'E01.370.390.175', 'E04.502.250.180', 'E04.950.774.155'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.858.700.750'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Immunohistochemical studies of the HPL concentration in the mature human placenta]. | The differences of HPL-concentration in different sections of the placenton are shown in twenty placentas by means of immunocytochemistry. The less mature villi of the plascenton centre demonstrate a lower concentration of HPL as the placenton periphery. The X-cells of the basal plate are recognised of fetal origin bec... | ['Female', 'Humans', 'Immunochemistry', 'Placenta', 'Placental Lactogen', 'Pregnancy', 'Pregnancy Trimester, Third'] | 6,540,933 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.201.486', 'H01.181.122.605', 'H02.403.044.500'], ['A16.710'], ['D06.472.699.649.692', 'D12.644.548.726.692', 'D12.776.780.650'], ['G08.686.784.769'], ['G08.686.707.520']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A survey on Swiss women's preferred menstrual/withdrawal bleeding pattern over different phases of reproductive life and with use of hormonal contraception. | BACKGROUND: Today, options for bleeding-free lifestyle are actively promoted by the media, the pharmaceutical industry and health specialists. With regard to contraceptive counselling it is important to find out what women really want.METHODS: In the present study we collected information on women's attitudes towards m... | ['Adolescent', 'Adult', 'Age Factors', 'Contraceptive Agents, Female', 'Educational Status', 'Female', 'Humans', 'Menstruation', 'Middle Aged', 'Patient Preference', 'Surveys and Questionnaires', 'Switzerland', 'Young Adult'] | 24,856,072 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.696.875.360.276', 'D27.505.954.705.360.276'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.605.428'], ['M01.060.116.630'], ['F01.100.150.750.625.500', 'F01.145.488.887.625.500', 'N04.452.822.700.500', 'N0... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
p38 mitogen-activated protein kinase-induced nuclear factor kappa-light-chain-enhancer of activated B cell activity is required for neuroprotection in retinal ischemia/reperfusion injury. | PURPOSE: In our previous study, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-êB) played a neuroprotective role in retinal ischemia/reperfusion (I/R) injury in rats. However, the mechanism of NF-êB neuroprotection is still unclear. We hypothesize that p38 mitogen-activated protein kinase (MAPK) is ... | ['Animals', 'Gene Expression Regulation', 'Imidazoles', 'Male', 'Protein Kinase Inhibitors', 'Proto-Oncogene Proteins c-bcl-2', 'Pyridines', 'RNA, Messenger', 'RNA, Small Interfering', 'Rats', 'Reperfusion Injury', 'Retina', 'Retinal Ganglion Cells', 'Signal Transduction', 'Transcription Factor RelA', 'p38 Mitogen-Acti... | 22,876,136 | [['B01.050'], ['G05.308'], ['D03.383.129.308'], ['D27.505.519.389.755'], ['D12.644.360.075.718', 'D12.776.476.075.718', 'D12.776.624.664.700.169'], ['D03.383.725'], ['D13.444.735.544'], ['D13.150.650.700', 'D13.444.735.150.700', 'D13.444.735.790.552.875'], ['B01.050.150.900.649.313.992.635.505.700'], ['C14.907.725', 'C... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of home visiting by nurses on maternal and child mortality: results of a 2-decade follow-up of a randomized clinical trial. | IMPORTANCE: Mothers and children living in adverse contexts are at risk of premature death.OBJECTIVE: To determine the effect of prenatal and infant/toddler nurse home visiting on maternal and child mortality during a 2-decade period (1990-2011).DESIGN, SETTING, AND PARTICIPANTS: A randomized clinical trial was designe... | ['African Americans', 'Child', 'Child Health Services', 'Child Mortality', 'Child Welfare', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'House Calls', 'Humans', 'Infant', 'Male', 'Maternal Health Services', 'Maternal Mortality', 'Nurses, Community Health', 'Pregnancy', 'Pregnancy Outcome', 'Survival Analysis', '... | 25,003,802 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.406'], ['N02.421.143.130'], ['E05.318.308.985.550.287', 'N01.224.935.698.150', 'N06.850.505.400.975.550.287', 'N06.850.520.308.985.550.287'], ['I01.880.787.293'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.7... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Discovery and annotation of small proteins using genomics, proteomics, and computational approaches. | Small proteins (10-200 amino acids [aa] in length) encoded by short open reading frames (sORF) play important regulatory roles in various biological processes, including tumor progression, stress response, flowering, and hormone signaling. However, ab initio discovery of small proteins has been relatively overlooked. R... | ['Computational Biology', 'Expressed Sequence Tags', 'Genomics', 'Molecular Sequence Annotation', 'Molecular Sequence Data', 'Open Reading Frames', 'Plant Leaves', 'Plant Proteins', 'Populus', 'Proteomics', 'RNA, Untranslated', 'Research Design'] | 21,367,939 | [['H01.158.273.180', 'L01.313.124'], ['G05.360.340.024.340.137.275'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.393.760.479', 'L01.453.245.667.580'], ['L01.453.245.667'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['A18.024.812'], ['D12.776.765'], ['B01.650.940.800.575.912.250.859.797.875.453']... | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Ossifying fibroma of the inferior turbinate. | Hypertrophy of inferior turbinate is a common condition, especially with nasal septum deviation. Sometimes, the cause of hypertrophy of inferior turbinate can be fibro-osseous lesions. Benign, rare, and non-aggressive fibro-osseous neoplasms such as ossifying fibroma can affect paranasal sinuses. Isolated inferior turb... | ['Adult', 'Bone Neoplasms', 'Female', 'Fibroma, Ossifying', 'Humans', 'Hypertrophy', 'Nasal Obstruction', 'Treatment Outcome', 'Turbinates'] | 21,595,621 | [['M01.060.116'], ['C04.588.149', 'C05.116.231'], ['C04.557.450.565.575.400', 'C04.557.450.565.590.340.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['C08.460.525', 'C08.618.846.185.525', 'C09.603.525'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['A02.835.232.781.324.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structural and functional studies of the potent anti-HIV chemokine variant P2-RANTES. | The N-terminal region of the chemokine RANTES is critical for its function. A synthesized N-terminally modified analog of RANTES, P2-RANTES, was discovered using a phage display selection against living CCR5-expressing cells, and has been reported to inhibit HIV-1 env-mediated cell-cell fusion at subnanomolar levels (H... | ['Amino Acid Sequence', 'Chemokine CCL5', 'Crystallography, X-Ray', 'HIV Fusion Inhibitors', 'HIV Infections', 'HIV-1', 'HeLa Cells', 'Heparin', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Mutation', 'Protein Binding'] | 19,722,264 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.644.276.374.200.110.250', 'D12.776.467.374.200.110.250', 'D23.125.300.110.250', 'D23.469.200.110.250', 'D23.529.374.200.110.250'], ['E05.196.309.742.225'], ['D27.505.519.957.500', 'D27.505.954.122.388.077.088.209', 'D27.505.954.122.388.538.500'], ['C01.221.250.875', 'C... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Genes within the HLA class II region confer both predisposition and resistance to primary biliary cirrhosis. | Nonradioactive sequence-specific oligonucleotide probes for the polymorphic HLA class II genes have been used to type samples from 51 Caucasian patients with the autoimmune liver disease, primary biliary cirrhosis, and 240 Caucasian controls. Although the allelic distribution at the DPB1 locus showed no significant var... | ['Causality', 'Disease Susceptibility', 'European Continental Ancestry Group', 'HLA-DQ Antigens', 'HLA-DR Antigens', 'Haplotypes', 'Histocompatibility Antigens Class II', 'Humans', 'Immunity, Innate', 'Liver Cirrhosis, Biliary', 'Polymerase Chain Reaction'] | 8,016,844 | [['N05.715.350.200', 'N06.850.490.625'], ['C23.550.291.687', 'G07.100.250'], ['M01.686.508.400'], ['D12.776.395.550.509.400.430', 'D12.776.543.550.440.400.430', 'D23.050.301.500.400.400.430', 'D23.050.301.500.450.400.430', 'D23.050.705.552.410.400.430', 'D23.050.705.552.450.400.430'], ['D12.776.395.550.509.400.440', 'D... | ['Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The value of computed tomography and ultrasound in assessment of pelvic lymph node metastases in patients with clinically locally confined carcinoma of the prostate. | With the aim of detecting any metastases in pelvic lymph nodes, computed tomography (CT) was performed in 42 patients with clinically localized prostatic carcinoma, and ultrasound (US) examination in 35 of them, prior to pelvic lymphadenectomy. CT was positive in only one patient, and US was negative in all examined pa... | ['Aged', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Pelvic Neoplasms', 'Prostatic Neoplasms', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 3,291,093 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['C04.588.699'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E0... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in racial-ethnic disparities in use and adequacy of mental health care in the United States, 1990–2003. | OBJECTIVE: This study examined changes in white-black and white-Latino disparities in the use of any mental health care and minimally adequate mental health care.METHODS: Using data from the 1990–1992 National Comorbidity Survey (NCS) and the 2001–2003 National Comorbidity Survey Replication (NCS-R), th... | ['Adolescent', 'Adult', 'African Americans', 'Anxiety Disorders', 'Continental Population Groups', 'Ethnic Groups', 'European Continental Ancestry Group', 'Female', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Healthcare Disparities', 'Hispanic Americans', 'Humans', 'Male', 'Mental Health Servi... | 22,422,014 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['F03.080'], ['M01.686.508'], ['M01.686.754', 'N01.224.317'], ['M01.686.508.400'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['N04.590.374.380', 'N05.300.493'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Application of the generalized connectivity-based hierarchy to biomonomers: enthalpies of formation of cysteine and methionine. | Computational challenges toward an accurate determination of the enthalpies of formation of amino acids are partly due to the nonavailability of systematic error-canceling thermochemical procedures for such biomonomers. Recently, we developed the connectivity-based hierarchy (CBH) to accurately compute the enthalpies o... | ['Cysteine', 'Methionine', 'Quantum Theory', 'Thermodynamics'] | 23,697,551 | [['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['H01.671.579.800'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Live and heat-killed Lactobacillus spp. interfere with Streptococcus mutans and Streptococcus oralis during biofilm development on titanium surface. | OBJECTIVES: This research investigates the ability of live and heat-killed (HK) Lactic Acid Bacteria (LAB) to interfere with Streptococcus mutans ATCC 25175 and Streptococcus oralis ATCC 9811 during biofilm formation.DESIGN: Eight Lactobacillus spp. and two oral colonizers, pathogenic Streptococcus mutans and resident ... | ['Antibiosis', 'Bacterial Adhesion', 'Biofilms', 'Hot Temperature', 'Lactobacillus', 'Streptococcus mutans', 'Streptococcus oralis', 'Surface Properties', 'Titanium'] | 28,193,570 | [['G06.550.050', 'G16.062'], ['G06.099.050'], ['A20.593', 'G06.120'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['B03.353.750.737.872.875.520', 'B... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A cluster randomised controlled trial of pharmacist led statin outreach support (SOS) in primary care: design and baseline characteristics. | BACKGROUND: Statins reduce the risk of vascular events, however statin prescribing is often sub optimal and better evidence is needed to inform quality improvements. The Statin Outreach Support (SOS) trial was designed to test the efficacy of pharmacist led educational outreach directed at General Practices, aiming to ... | ['Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Cerebrovascular Disorders', 'Drug Prescriptions', 'Female', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Hypercholesterolemia', 'Male', 'Middle Aged', 'Peripheral Vascular Diseases', 'Pharmacists', 'Physicians, Primary Care', "Practice Patterns, ... | 20,348,032 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['C10.228.140.300', 'C14.907.253'], ['E02.319.307', 'N02.421.668.778.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['C18.452.584.500.500.396'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prevalence and distribution of hip and knee joint replacements and hip implants in older Americans by the end of life. | BACKGROUND AND AIMS: Hip and knee replacements have become increasingly common in the older population but the prevalence of these procedures and the potential impact on functioning towards the end of life have not been previously described. The aim of this study was to estimate the rates and distribution of hip and kn... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Female', 'Humans', 'Male', 'Motor Activity', 'Osteoarthritis, Hip', 'Osteoarthritis, Knee', 'Prevalence', 'Risk Factors', 'Sex Distribution', 'Social Class', 'United States'] | 12,841,420 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[50 years of hepatology - from therapeutic nihilism to targeted therapies]. | Over the past 50 years significant progress has been made in the whole field of hepatology. Part of this is translation of basic research (biochemistry, immunology, virology, molecular biology and others) into clinical hepatology. This enabled us to understand more about the pathogenesis of liver diseases and led to th... | ['Anniversaries and Special Events', 'Gastroenterology', 'Germany', 'Hepatectomy', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Liver Diseases', 'Liver Transplantation', 'Molecular Targeted Therapy'] | 23,585,265 | [['K01.400.095', 'N04.452.822.070'], ['H02.403.429.405'], ['Z01.542.315'], ['E04.210.556'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['E02.319.574']] | ['Humanities [K]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels. | Long and short QT syndromes associated with loss and gain of human ether-a-go-go-related gene (hERG) channel activity, respectively, can cause life-threatening arrhythmias. As such, modulation of hERG channel activity is an important consideration in the development of all new therapeutic agents. In the present study, ... | ['Action Potentials', 'Animals', 'Binding Sites', 'CHO Cells', 'Cricetinae', 'Cricetulus', 'Data Interpretation, Statistical', 'Dose-Response Relationship, Drug', 'Electric Conductivity', 'Ether-A-Go-Go Potassium Channels', 'Heart Ventricles', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Isoindoles', 'Kinetic... | 18,042,732 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['G02.111.570.120'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.83... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Genome-wide analysis in endangered populations: a case study in Barbaresca sheep. | Analysis of genomic data is becoming increasingly common in the livestock industry and the findings have been an invaluable resource for effective management of breeding programs in small and endangered populations. In this paper, with the goal of highlighting the potential of genomic analysis for small and endangered ... | ['Animals', 'Conservation of Natural Resources', 'Endangered Species', 'Female', 'Gene Frequency', 'Genetic Variation', 'Genomics', 'Genotyping Techniques', 'Haplotypes', 'Homozygote', 'Inbreeding', 'Linkage Disequilibrium', 'Male', 'Polymorphism, Single Nucleotide', 'Population Density', 'Sheep'] | 28,077,191 | [['B01.050'], ['J01.256', 'N06.230.080'], ['B01.050.050.565', 'G16.500.275.157.049.250', 'N06.230.080.200', 'N06.230.124.049.250'], ['G05.330'], ['G05.365'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.393.442'], ['G05.380.360'], ['G05.380.554'], ['E05.820.150.520', 'G05.090.403'], ['G05.348.500'], ['G05.365.... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Premenstrual symptoms: a reinterpretation. | Conclusions regarding the physiological basis and disruptive effects of premenstrual symptoms may be biased because of the reliance on self-report questionnaires as a source of data. In order to examine this possible bias, women's perceptions of their cycle phase were separated experimentally from actual cycle phase. W... | ['Adolescent', 'Adult', 'Body Water', 'Female', 'Humans', 'Pain', 'Premenstrual Syndrome', 'Research Design', 'Surveys and Questionnaires'] | 560,058 | [['M01.060.057'], ['M01.060.116'], ['A12.207.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['C23.550.568.968'], ['E05.581.500', 'H01.770.644.728'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Multiple roles of phosphatidylinositol 3-kinase in regulation of glucose transport, amino acid transport, and glucose transporters in L6 skeletal muscle cells. | Phosphatidylinositol 3-kinase (PI3k) activity is required for the insulin stimulation of glucose transport in adipocytes and Chinese hamster ovary cells. Wortmannin (WM), an inhibitor of PI3k, inhibits the stimulation of glucose transport by insulin and the gain of glucose transporters at the cell surface. However, the... | ['Amino Acids', 'Androstadienes', 'Biological Transport', 'Cells, Cultured', 'Glucose', 'Glucose Transporter Type 1', 'Glucose Transporter Type 3', 'Glucose Transporter Type 4', 'Insulin', 'Monosaccharide Transport Proteins', 'Muscle Proteins', 'Muscle, Skeletal', 'Nerve Tissue Proteins', 'Phosphatidylinositol 3-Kinase... | 7,664,650 | [['D12.125'], ['D04.210.500.054.079.129'], ['G03.143'], ['A11.251'], ['D09.947.875.359.448'], ['D12.776.157.530.500.500.500', 'D12.776.157.530.937.563.500', 'D12.776.543.585.500.500.500', 'D12.776.543.585.937.625.500'], ['D12.776.157.530.500.500.875', 'D12.776.157.530.937.563.875', 'D12.776.543.585.500.500.875', 'D12.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Identification of multidrug resistance related genes in leukemia by suppression subtractive hybridization]. | OBJECTIVE: To clone and screen genes related to multidrug resistance (MDR) in leukemia.METHODS: Suppression subtractive hybridization (SSH) was performed to profile differentially expressed genes between a MDR leukemia cell line (K562/DOX, as tester) and its parent cell line (K562, as driver). Reverse Northern dot blot... | ['Blotting, Northern', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Gene Library', 'Genes, MDR', 'Humans', 'K562 Cells', 'Leukemia', 'NADH Dehydrogenase', 'Nucleic Acid Hybridization', 'Reverse Transcriptase Polymerase Chain Reaction', 'Ribosomal Proteins'] | 12,679,003 | [['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G07.690.773.984.300'], ['G07.690.773.984.395'], ['G05.360.325'], ['G05.360.340.024.340.361', 'G05.360.340.024.340.645.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.510', 'A11.251.860.180.510', 'A11.443.240.497.480'], ['C04.557.337'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Static and moving phantom studies for radiation treatment planning in a positron emission tomography and computed tomography (PET/CT) system. | OBJECTIVE: To determine an appropriate threshold value for delineation of the target in positron emission tomography (PET) and to investigate whether PET can delineate an internal target volume (ITV), a series of phantom studies were performed.METHODS: An ellipse phantom (background) was filled with 1028 Bq/ml of [(18)... | ['Artifacts', 'Fluorodeoxyglucose F18', 'Humans', 'Imaging, Three-Dimensional', 'Motion', 'Patient Care Planning', 'Phantoms, Imaging', 'Positron-Emission Tomography', 'Radiopharmaceuticals', 'Radiotherapy Planning, Computer-Assisted', 'Reference Standards', 'Subtraction Technique', 'Tomography, X-Ray Computed'] | 18,756,360 | [['E05.047'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['G01.482'], ['N04.590.233.624'], ['E07.671'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', 'E01.370.350.825.800.399', 'E01.370.384.730.800.399'], ['D27.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Dietary cholesterol degrades rabbit long term memory for discrimination learning but facilitates acquisition of discrimination reversal. | We have shown previously that feeding dietary cholesterol before learning can improve acquisition whereas feeding cholesterol after learning can degrade long term memory. To examine these different findings within a single paradigm, we fed groups of rabbits 2% cholesterol or normal chow with or without 0.12 ppm copper ... | ['Acoustic Stimulation', 'Animals', 'Cholesterol, Dietary', 'Conditioning, Classical', 'Conditioning, Eyelid', 'Discrimination Learning', 'Male', 'Memory, Long-Term', 'Nictitating Membrane', 'Rabbits', 'Reversal Learning'] | 24,076,265 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['F02.463.425.179.308'], ['F02.463.425.179.408'], ['F02.463.425.280'], ['F02.463.425.540.305'], ['A13.660'], ['B01.050.150.900.649.313.968.700'], ['F02.463.425.798']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serological relationships between Escherichia coli and Salmonella smooth- and rough-mutant lipopolysaccharides as revealed by enzyme-linked immunosorbent assay for human immunoglobulin G antiendotoxin antibodies. | Reactions of sera from healthy blood donors to smooth and rough mutant lipopolysaccharides (LPS) from Escherichia coli O111:B4 and Salmonella minnesota which had been complexed with polymyxin B were determined by enzyme-linked immunosorbent assay. Relative enzyme-linked immunosorbent assay reactivities were examined fo... | ['Antibodies, Bacterial', 'Antigens, Bacterial', 'Bacterial Toxins', 'Carbohydrate Sequence', 'Endotoxins', 'Enzyme-Linked Immunosorbent Assay', 'Escherichia coli', 'Glycolipids', 'Humans', 'Immunoglobulin G', 'Lipopolysaccharides', 'Mutation', 'Salmonella', 'Serotyping'] | 3,312,008 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D23.946.123'], ['G02.111.570.160', 'L01.453.245.667.160'], ['D23.946.123.329'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B03.44... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development of an immunoassay for rapid detection of ganglioside GM(1) mimicry in Campylobacter jejuni strains. | Mimicry of peripheral nerve gangliosides by Campylobacter jejuni lipopolysaccharides (LPSs) has been proposed to induce cross-reacting antiganglioside antibodies in Guillain-Barr? syndrome (GBS). Because current methods for LPS characterization are labor-intensive and inhibit the screening of large numbers of strains, ... | ['Campylobacter jejuni', 'Chromatography, Thin Layer', 'Epitopes', 'G(M1) Ganglioside', 'Humans', 'Immunoassay', 'Lipopolysaccharides', 'Molecular Mimicry'] | 11,283,076 | [['B03.440.180.425', 'B03.660.150.235.250.500.375'], ['E05.196.181.400.537'], ['D23.050.550'], ['D09.400.410.420.025.475.390', 'D10.390.470.025.475.390', 'D10.570.877.360.025.475.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.05... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cerebral vasospasms after traumatic subarachnoid hemorrhage]. | We report the case of a 72-year-old man suffering from posttraumatic subarachnoidal hemorrhage. After recovering from the initial impaired consciousness and posttraumatic psychosis the patient deteriorated again 7 days after the accident. Cerebral vasospasm was found to be the underlying cause. So far few publications ... | ['Aged', 'Blood Flow Velocity', 'Brain Concussion', 'Echoencephalography', 'Electroencephalography', 'Evoked Potentials', 'Humans', 'Ischemic Attack, Transient', 'Male', 'Muscle, Smooth, Vascular', 'Neurologic Examination', 'Subarachnoid Hemorrhage', 'Tomography, X-Ray Computed'] | 1,944,713 | [['M01.060.116.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['E01.370.350.578.937.260', 'E01.370.350.700.560.260', 'E01.370.350.850.260', 'E01.370.376.537.750.260', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of chloride and diamide on angiotensin converting enzyme from sheep testis and epididymis. | Effect of chloride and diamide on testicular and epididymal angiotensin converting enzyme (ACE) activity was investigated using Hip-His-Leu as substrate in sheep. The chloride ions functioned as ACE activators, however, there was no linear correlation between the two. The optimum chloride concentrations were 500 mM for... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Chlorides', 'Diamide', 'Epididymis', 'Male', 'Peptidyl-Dipeptidase A', 'Sheep', 'Sulfhydryl Reagents', 'Testis'] | 9,536,650 | [['D27.505.519.389.745.085'], ['B01.050'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D02.172.300'], ['A05.360.444.371'], ['D08.811.277.656.350.350.687'], ['B01.050.150.900.649.313.500.380.791'], ['D27.720.470.410.700'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.312.782']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Balancing measures or a balanced accounting of improvement impact: a qualitative analysis of individual and focus group interviews with improvement experts in Scotland. | BACKGROUND: As quality improvement (QI) programmes have become progressively larger scale, the risks of implementation having unintended consequences are increasingly recognised. More routine use of balancing measures to monitor unintended consequences has been proposed to evaluate overall effectiveness, but in practic... | ['Attitude of Health Personnel', 'Focus Groups', 'Goals', 'Health Personnel', 'Humans', 'Interviews as Topic', 'Outcome and Process Assessment, Health Care', 'Quality Improvement', 'Scotland', 'State Medicine'] | 29,055,901 | [['F01.100.050', 'N05.300.100'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.658.500'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N04.761.559', 'N05.715.360.575'], ['J0... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
Molecular basis involved in the blocking effect of antidepressant metergoline on C-type inactivation of Kv1.4 channel. | Voltage-gated potassium channels (VGKCs) are transmembrane ion channels specific for potassium. Currently there are nine kinds of VGKCs. Kv1.4 is one of shaker-related potassium channels. It is a representative alpha subunit of potassium channels that can inactivate A type-currents, leading to N pattern inactivation. I... | ['Animals', 'Antidepressive Agents', 'Binding Sites', 'Kinetics', 'Kv1.4 Potassium Channel', 'Lectins, C-Type', 'Metergoline', 'Models, Molecular', 'Molecular Docking Simulation', 'Mutagenesis, Site-Directed', 'Neurons', 'Oocytes', 'Potassium Channel Blockers', 'Potassium Channels, Voltage-Gated', 'Rats', 'Structure-Ac... | 30,465,811 | [['B01.050'], ['D27.505.954.427.700.122'], ['G02.111.570.120'], ['G01.374.661', 'G02.111.490'], ['D12.776.157.530.400.600.900.500.233', 'D12.776.543.550.450.750.900.500.233', 'D12.776.543.585.400.750.900.624.233'], ['D12.776.503.280'], ['D03.132.327.287.630', 'D03.633.400.439.630'], ['E05.599.595'], ['E05.599.595.249',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Leptin-resistant obese mice have paradoxically low biliary cholesterol saturation. | BACKGROUND: Human obesity is associated with leptin resistance, elevated serum glucose and lipids, hepatic steatosis, and cholesterol gallstone formation. These gallstones are thought to result from hypersecretion of biliary cholesterol as well as biliary stasis. Leptin-resistant Lep(db) obese mice, which are known to ... | ['Animals', 'Bile', 'Blood Glucose', 'Cholesterol', 'Crystallization', 'Drug Resistance', 'Female', 'Gallbladder', 'Leptin', 'Lipid Metabolism', 'Liver', 'Mice', 'Mice, Inbred C57BL', 'Obesity', 'Organ Size', 'Vacuoles'] | 12,947,343 | [['B01.050'], ['A12.200.087'], ['D09.947.875.359.448.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.196.300', 'G02.171'], ['G07.690.773.984'], ['A03.159.439'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['G03.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CT differentiation of pneumonic-type bronchioloalveolar cell carcinoma and infectious pneumonia. | The objective was to analyse the potential of CT to distinguish pneumonic-type bronchioloalveolar cell carcinoma (BAC) from infectious pneumonia. The study consisted of 21 patients with pathologically proven BAC and 30 patients with infectious pneumonia. Both groups of patients had patchy or diffuse consolidation of mo... | ['Adenocarcinoma, Bronchiolo-Alveolar', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Diagnosis, Differential', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Pneumonia, Bacterial', 'Tomography, X-Ray Computed'] | 11,459,727 | [['C04.557.470.200.025.022.500', 'C04.588.894.797.520.055.500'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['C01.150.252.620', 'C01.748.610.540'... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Interexaminer Reliability of Seated Motion Palpation for the Stiffest Spinal Site. | OBJECTIVES: The purpose of this study was to assess the interexaminer reliability of palpation for stiffness in the cervical, thoracic, and lumbar spinal regions.METHODS: In this secondary data analysis, data from 70 patients from a chiropractic college outpatient clinic were analyzed. Two doctors of chiropractic palpa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Movement', 'Observer Variation', 'Palpation', 'Reproducibility of Results', 'Spine', 'Young Adult'] | 30,449,306 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E01.370.600.600'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A coverage and slicing dependencies analysis for seeking software security defects. | Software security defects have a serious impact on the software quality and reliability. It is a major hidden danger for the operation of a system that a software system has some security flaws. When the scale of the software increases, its vulnerability has becoming much more difficult to find out. Once these vulnerab... | ['Algorithms', 'Computer Security', 'Software'] | 24,982,957 | [['G17.035', 'L01.224.050'], ['L01.224.134', 'N04.452.910.200'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
An alternative diagnostic test for active M?ni?re's disease and cochlear hydrops using high-pass noise masked responses: the complex amplitude ratio. | We [Don et al.: Otol Neurotol 2005;26:711-722] previously demonstrated that patients diagnosed with an active case of M?ni?re's disease could be distinguished from non-M?ni?re's normal-hearing subjects by a special auditory brainstem response method involving clicks and ipsilateral high-pass masking pink noise. Specifi... | ['Acoustic Stimulation', 'Audiometry, Pure-Tone', 'Auditory Threshold', 'Brain Stem', 'Endolymphatic Hydrops', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Meniere Disease', 'Perceptual Masking', 'Predictive Value of Tests', 'Probability', 'Reaction Time', 'Reference ... | 17,664,867 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['E01.370.382.375.060.055'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['A08.186.211.132'], ['C09.218.568.217'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[A study on acute multiple sclerosis]. | With the purpose of investigating the clinicopathological changes and the criterion for differential diagnosis, ten cases of Acute multiple sclerosis (AMS) were analysed. The data suggested that its clinical course was an acute neurologic event characterized by psychic syndrome, paralysis and incontinence of bowel move... | ['Acute Disease', 'Adult', 'Brain', 'Diagnosis, Differential', 'Encephalomyelitis, Acute Disseminated', 'Female', 'Humans', 'Male', 'Multiple Sclerosis', 'Retrospective Studies'] | 9,206,213 | [['C23.550.291.125'], ['M01.060.116'], ['A08.186.211'], ['E01.171'], ['C10.114.375.225', 'C10.228.140.695.562.225', 'C10.314.350.225', 'C20.111.258.250.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation, characterization, and EGFP expression in the buffalo (Bubalus bubalis) mammary gland epithelial cell line. | This study was aimed to establish a buffalo mammary epithelial cells (BuMECs) line and maintain it for long-term by subculturing. BuMECs isolated from lactating buffalo mammary glands were cultured on a collagen matrix gel. BuMECs expressed significant amounts of the epithelial cell specific marker cytokeratin 18 as de... | ['Animals', 'Buffaloes', 'Cell Culture Techniques', 'Cell Line', 'DNA Primers', 'Epithelial Cells', 'Female', 'Green Fluorescent Proteins', 'Immunohistochemistry', 'Keratin-18', 'Lactation', 'Mammary Glands, Animal', 'Milk Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Transfection'] | 23,180,034 | [['B01.050'], ['B01.050.150.900.649.313.500.380.135'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A11.436'], ['D12.776.532.265'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Novel loci fsd6.1 and Csgl3 regulate ultra-high fruit spine density in cucumber. | KEY MESSAGE: Quantitative Trait Loci (QTL) analysis of multiple populations in multiple environments revealed that the fsd6.2 locus, which includes the candidate gene Csgl3, controls high fruit spine density in natural cucumbers. GWAS identified a novel locus fsd6.1, which regulates ultra-high fruit spine density in co... | ['China', 'Chromosome Mapping', 'Cucumis sativus', 'Domestication', 'Fruit', 'Genes, Plant', 'Genetic Association Studies', 'Genetic Linkage', 'Genetic Variation', 'Phenotype', 'Phylogeny', 'Quantitative Trait Loci'] | 30,242,492 | [['Z01.252.474.164'], ['E05.393.183'], ['B01.650.940.800.575.912.250.300.188.666'], ['J01.040.330'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['E05.393.385'], ['G05.348'], ['G05.365'], ['G05.695'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.360.340.024... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
Successful treatment of threatening limb loss ischemia of the upper limb caused by ergotamine. A case report and review of the literature. | We report a case of ischemia limited to the upper limb caused by chronic use of ergotamine. The effect of this drug was not related to hypersensitivity or to the potentiating effects of other medications. The patient was successfully treated discontinuing ergotamine and administering an alpha-blocking agent for three m... | ['Administration, Oral', 'Adrenergic alpha-Antagonists', 'Angiography', 'Arm', 'Arterial Occlusive Diseases', 'Ergotamine', 'Female', 'Follow-Up Studies', 'Humans', 'Ischemia', 'Middle Aged', 'Migraine Disorders', 'Prazosin', 'Serotonin Antagonists', 'Sumatriptan', 'Time Factors', 'Vasoconstrictor Agents'] | 11,887,064 | [['E02.319.267.100'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A01.378.800.075'], ['C14.907.137'], ['D03.132.327.412.400', 'D03.633.400.562.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Localization of myosin heavy chain A in the human pathogen Entamoeba histolytica. | To recognize myosin II in trophozoites of the human pathogen Entamoeba histolytica, a specific antimyosin polyclonal serum was raised against a fusion protein consisting of a 146-amino-acid fragment of the myosin II heavy chain A of E. histolytica (MhcA) fused with beta-galactosidase. The hybrid protein was encoded by ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Compartmentation', 'Cell Movement', 'Entamoeba histolytica', 'Fluorescent Antibody Technique', 'Molecular Sequence Data', 'Myosins', 'Oligodeoxyribonucleotides', 'Protozoan Proteins', 'Recombinant Fusion Proteins', 'Restriction Mapping'] | 8,432,587 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.128'], ['G04.198', 'G07.568.500.180'], ['B01.046.500.100.700.335.330'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lymphocytosis of large granular lymphocytes in splenectomized subjects. | Lymphocytosis of large granular lymphocytes (LGL) has been observed in 6 patients splenectomized for various pathological conditions. In all of them the LGL count was higher than 3.5 x 10(9)/l. No patient showed neutropenia nor suffered from rheumatoid arthritis. A surface markers heterogeneity was observed by immunoph... | ['Adult', 'Aged', 'Antigens, CD', 'Female', 'Humans', 'Leukocyte Count', 'Lymphocytes', 'Lymphocytosis', 'Male', 'Middle Aged', 'Splenectomy'] | 3,271,571 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105.595'], ['A11.118.637.555... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Frequent 911 Fall Calls in Older Adults: Opportunity for Injury Prevention Strategies. | OBJECTIVES: To evaluate the utility of monitoring emergency medical services (EMS) call patterns to identify older adults who may benefit from targeted fall prevention and medical monitoring strategies.DESIGN: Retrospective chart review of EMS fall-related care. The HealthEMS database for the community surveyed was que... | ['Accidental Falls', 'Aged', 'Aged, 80 and over', 'Databases, Factual', 'Emergency Medical Dispatch', 'Female', 'Humans', 'Independent Living', 'Male', 'Middle Aged', 'Patient Acceptance of Health Care', 'Retrospective Studies'] | 30,019,749 | [['N06.850.135.122'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['N02.421.297.043'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.050.500', 'N01.224.791.550', 'N06.850.505.400.800.550'], ['M01.060.116.630'], ['F01.100.150.750.500', 'F01.145.488.887.500',... | ['Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
[Effect of polycyclic aromatic hydrocarbons on the vertical distribution of denitrifying genes in river sediments]. | To establish the relationship between polycyclic aromatic hydrocarbons (PAHs) and various stages of denitrification under denitrifying conditions in sediments, we examined the impact of PAHs on the vertical distribution of special denitrifying genes. In March of 2011, sediment samples were collected from three represen... | ['Bacteria, Anaerobic', 'Denitrification', 'Genes, Bacterial', 'Geologic Sediments', 'Nitrates', 'Oxidation-Reduction', 'Polycyclic Aromatic Hydrocarbons', 'Rivers', 'Water Pollutants, Chemical'] | 23,233,993 | [['B03.130'], ['G02.111.587.250', 'G02.607.560.250', 'G16.500.768.249'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G01.311.330', 'G16.500.320'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['G02.700', 'G03.295.531'], ['D02.455.426.559.847', 'D04.615'], ['G01.311... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Identification of antigens reacting with anti-Candida albicans germ tube antibodies. | Anti-Candida albicans germ tube antibodies can be induced in rabbits immunized with different C. albicans extracts. Antigens responsible for the induction of those antibodies have molecular weights of approximately 230-250, 62, 43 and 41 kDa. These antigens are present in the cell wall of both C. albicans morphological... | ['Animals', 'Antibodies, Fungal', 'Antigen-Antibody Reactions', 'Antigens, Fungal', 'Blotting, Western', 'Candida albicans', 'Cell Wall', 'Electrophoresis, Polyacrylamide Gel', 'Epitopes', 'Fluorescent Antibody Technique', 'Molecular Weight', 'Rabbits'] | 1,383,025 | [['B01.050'], ['D12.776.124.486.485.114.179', 'D12.776.124.790.651.114.179', 'D12.776.377.715.548.114.179'], ['G12.122'], ['D23.050.202'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['A11... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhanced activation of peroxymonosulfte by LaFeO3 | In this study, the effect of various supports on activation of peroxymonosulfate and consequent degradation of Acid Orange 7 (AO7) in aqueous solutions was examined at the presence of LaFeO3 perovskite as catalyst. Results showed that the AO7 degradation efficiency by LaFeO3 supported on different supports was in an or... | ['Aluminum Oxide', 'Azo Compounds', 'Benzenesulfonates', 'Calcium Compounds', 'Catalysis', 'Environmental Pollutants', 'Hydroxyl Radical', 'Iron', 'Models, Chemical', 'Oxidation-Reduction', 'Oxides', 'Peroxides', 'Silicon Dioxide', 'Sulfates', 'Titanium'] | 31,394,447 | [['D01.056.050', 'D01.650.550.050'], ['D02.172'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['D01.146'], ['G02.130'], ['D27.888.284'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['E05.599.495'], ['G02.700', 'G03.295.531... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Purification of cobra venom factor from phospholipase A contaminant. | It has been demonstrated that cobra venom factor prepared by the usual combination of ion exchange chromatography and sephadex gel filtration is contaminated by substantial amounts of a 'heavy' phospholipase A. The two activities may be separated by isoelectric focusing. Cobra venom factor focuses at pH between 5-75 an... | ['Chromatography, Gel', 'Chromatography, Ion Exchange', 'Hemolysis', 'Isoelectric Focusing', 'Phospholipases', 'Snake Venoms'] | 992,719 | [['E05.196.181.400.250'], ['E05.196.181.400.383'], ['C23.550.403', 'G12.122.545'], ['E05.196.401.663', 'E05.301.300.663'], ['D08.811.277.352.100.680', 'D08.811.277.352.640.700'], ['D20.888.850', 'D23.946.833.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Class II restorations with a polyacid-modified composite resin in primary molars placed in a dental practice: results of a two-year clinical evaluation. | This study evaluated the two-year success rate of a hybrid composite material (TPH-Spectrum; Dentsply DeTrey, Konstanz, Germany) and a polyacid-modified composite resin (Compoglass, Vivadent, Schaan, Liechtenstein) in Class II restorations placed in primary molars in a dental practice. In each of 52 children, at least ... | ['Acid Etching, Dental', 'Chi-Square Distribution', 'Child', 'Child, Preschool', 'Color', 'Compomers', 'Composite Resins', 'Dental Bonding', 'Dental Caries', 'Dental Marginal Adaptation', 'Dental Restoration, Permanent', 'Dentin-Bonding Agents', 'Female', 'Follow-Up Studies', 'Glass Ionomer Cements', 'Humans', 'Logisti... | 11,203,828 | [['E06.931.475.111'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['M01.060.406.448'], ['G01.590.540.199'], ['D05.750.716.822.308.300', 'D25.339.291.150', 'D25.339.816.500.300', 'D25.720.716.822.308.300', 'J01.637.051.339.291.150', 'J01.637.051.339.816.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Molecular clocks reduce plasmid loss rates: the R1 case. | Plasmids control their replication so that the replication frequency per plasmid copy responds to the number of plasmid copies per cell. High sensitivity amplification in replication response to copy number deviations generally reduces variation in copy numbers between different single cells, thereby reducing the plasm... | ['Bacteriocin Plasmids', 'Biological Clocks', 'Cell Division', 'Chromosome Segregation', 'Colicins', 'Computer Simulation', 'DNA Helicases', 'DNA Replication', 'DNA-Binding Proteins', 'Dimerization', 'Escherichia coli', 'Gene Dosage', 'Mathematics', 'Models, Genetic', 'Probability', 'Protein Biosynthesis', 'Proteins', ... | 10,704,315 | [['G05.360.600.080'], ['G07.180.562.094'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.144.220.220.625', 'G05.113.220.625'], ['D12.776.097.200'], ['L01.224.160'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['G02.111.225', 'G05.226'], ['D12.776.260'], ['G02.206', 'G03.230'], ['B0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Do thyroid-stimulating immunoglobulins cause non-toxic and toxic multinodular goitre? | The prevalence of serum thyroid-stimulating immunoglobulins (T.S.I.) in a variety of thyroid diseases was determined in 96 patients and 35 normal controls. Significantly elevated levels of T.S.I. were found not only in patients with Graves' disease and Hashimoto's thyroiditis but also in those with non-toxic and toxic ... | ['Adolescent', 'Adult', 'Aged', 'Goiter, Nodular', 'Graves Disease', 'Humans', 'Hyperthyroidism', 'Immunoglobulin G', 'Long-Acting Thyroid Stimulator', 'Middle Aged', 'Thyroiditis', 'Thyroiditis, Autoimmune'] | 76,846 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C19.874.283.501'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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