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Treatment of difficult-to-control blood pressure in a multidisciplinary clinic at a public hospital. | Cardiovascular morbidity and mortality in disadvantaged populations remains high. Few innovative strategies or services to treat chronic diseases have been critically analyzed in these patients. We evaluated our initial experiences with a newly established multidisciplinary clinic For the treatment of difficult-to-cont... | ['Adult', 'African Americans', 'Aged', 'Antihypertensive Agents', 'Chicago', 'Female', 'Follow-Up Studies', 'Health Knowledge, Attitudes, Practice', 'Hospitals, Public', 'Hospitals, Urban', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Outpatient Clinics, Hospital', 'P... | 12,749,616 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['D27.505.954.411.162'], ['Z01.107.567.875.350.350.200', 'Z01.107.567.875.510.350.200', 'Z01.433.305'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.100.150.500', 'N05.300.150.410'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Embolization of a renal transplant pseudoaneurysm following angiolipoma resection. A case report. | The development of a pseudoaneurysm in renal allografts is a well-known complication of percutaneous biopsy. However, the authors report a case of pseudoaneurysm formation in a renal cadaver allograft, following documented angiolipoma resection prior to transplantation. Treatment required superselective embolization wi... | ['Aneurysm, False', 'Angiolipoma', 'Cadaver', 'Embolization, Therapeutic', 'Humans', 'Kidney Neoplasms', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Renal Artery', 'Tissue Donors'] | 8,092,548 | [['C14.907.055.090'], ['C04.557.450.550.100'], ['C23.550.260.224'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human metabolism of phenothiazines to sulfoxides determined by a new high performance liquid chromatography--electrochemical detection method. | The metabolism of phenothiazine drugs may contribute to both their therapeutic and toxic actions by production of active metabolites in vivo. Idiosyncratic reactions or treatment failure may be a consequence of differing patterns of metabolism in different patients. In this report, a modification of our method for the ... | ['Chromatography, High Pressure Liquid', 'Fluphenazine', 'Humans', 'Phenothiazines', 'Sulfoxides'] | 3,377,833 | [['E05.196.181.400.300'], ['D02.886.369.326', 'D03.633.300.783.326'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.369', 'D03.633.300.783'], ['D02.886.640']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stability of cirrhotic systemic hemodynamics ensures sufficient splanchnic blood flow after living-donor liver transplantation in adult recipients with liver cirrhosis. | AIM: To investigate the correlation between systemic hemodynamics and splanchnic circulation in recipients with cirrhosis undergoing living-donor liver transplantation (LDLT), and to clarify how systemic hemodynamics impact on local graft circulation after LDLT.METHODS: Systemic hemodynamics, indocyanine green (ICG) el... | ['Adult', 'Blood Volume', 'Cardiac Output', 'Female', 'Hepatic Artery', 'Humans', 'Liver', 'Liver Cirrhosis', 'Liver Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Portal Vein', 'Radionuclide Imaging', 'Regional Blood Flow', 'Splanchnic Circulation', 'Tomography, Spiral Computed', 'Treatment Outcome', 'Ultr... | 17,990,357 | [['M01.060.116'], ['G09.188.130', 'G09.330.380.092'], ['E01.370.370.380.150', 'G09.330.380.124'], ['A07.015.114.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C06.552.630', 'C23.550.355.412'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.898.656'], ['M01.06... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acute pancreatitis associated with Mycoplasma pneumoniae: a case report of missed diagnosis. | OBJECTIVE: Mycoplasma pneumoniae is responsible for approximately 20% of community-acquired pneumonia. A wide variety of extrapulmonary manifestations related to M. pneumoniae infection can occur. The diagnosis of M. pneumoniae and its association with acute pancreatitis is briefly reviewed.CLINICAL PRESENTATION: We de... | ['Acute Disease', 'Appendicitis', 'Child', 'Diagnosis, Differential', 'Humans', 'Male', 'Mycoplasma pneumoniae', 'Pancreatitis', 'Tomography, X-Ray Computed'] | 12,123,103 | [['C23.550.291.125'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.860.580.553.553.650'], ['C06.689.750'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', '... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An Indian case of keratoderma hereditarium mutilans (Vohwinkel's syndrome) associated with ichthyosiform dermatosis. | Keratoderma hereditarium mutilans (KHM) or Vohwinkel's syndrome (VS) is usually inherited as an autosomal dominant disease, but a recessive type has occasionally been described. We report a 19-year-old male born to consanguineous parents, who presented with KHM associated with generalized ichthyosiform dermatosis. On e... | ['Adult', 'Diagnosis, Differential', 'European Continental Ancestry Group', 'Humans', 'Ichthyosis', 'India', 'Keratoderma, Palmoplantar', 'Male'] | 11,732,725 | [['M01.060.116'], ['E01.171'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.131.831.512', 'C16.614.492', 'C17.800.428.333', 'C17.800.804.512'], ['Z01.252.245.393'], ['C16.320.850.475', 'C17.800.428.435', 'C17.800.827.475']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[EFFECT OF CHANGE OF TISSUE INTERFACE STIFFNESS ON OSTEOGENIC DIFFERENTIATION OF RAT BONE MARROW MESENCHYMAL STEM CELLS]. | OBJECTIVE: To investigate the effect of tissue interface stiffness change on the spreading, proliferation, and osteogenic differentiation of rat bone marrow mesenchymal stem cells (BMSCs), and to find the suitable stiffness range for stem cell differentiation.METHODS: Bone marrow of male Sprague Dawley rats (4 weeks ol... | ['Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Cells, Cultured', 'Male', 'Mesenchymal Stem Cells', 'Osteogenesis', 'Rats', 'Rats, Sprague-Dawley', 'Tissue Engineering'] | 29,786,346 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251'], ['A11.329.830.500', 'A11.872.590.500'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.481.500.311.500', 'J01.293.069.249.500']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Removal of uranium(VI) from aqueous solutions and nuclear industry effluents using humic acid-immobilized zirconium-pillared clay. | Removal of uranium [U(VI)] from aqueous solutions with humic acid-immobilized zirconium-pillared clay (HA-Zr-PILC) was investigated using a batch adsorption technique. The adsorbent was characterized using XRD, FTIR, SEM, TG/DTG, surface area analyzer and potentiometric titration. The effects of pH, contact time, initi... | ['Adsorption', 'Aluminum Silicates', 'Clay', 'Humic Substances', 'Hydrogen-Ion Concentration', 'Solutions', 'Spectroscopy, Fourier Transform Infrared', 'Uranium', 'Uranium Compounds', 'Waste Disposal, Fluid', 'Water Pollutants, Radioactive', 'Zirconium'] | 20,045,229 | [['G01.030', 'G02.020'], ['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D20.721.250', 'G01.311.820.250', 'G16.500.275.815.250', 'N06.230.600.250'], ['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['G02.300'], ['D26.776'], ['E05.196.712.726.676.700', 'E05.196.8... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stimulation of protein tyrosine phosphorylation in human B cells after ligation of the beta 1 integrin VLA-4. | B lymphocytes express several adhesion molecules that are involved in cell-cell and cell-extracellular matrix interactions. The alpha 4 beta 1 integrin VLA-4, expressed on pre-B and mature/activated B cells, mediates adhesion of these cells to its two ligands, VCAM-1 and fibronectin. Recent evidence suggests that VLA-4... | ['Antigens, CD', 'B-Lymphocytes', 'Cell Adhesion', 'Cell Differentiation', 'Cell Line', 'Humans', 'Integrin beta1', 'Phosphorylation', 'Proteins', 'Receptors, Very Late Antigen', 'Tyrosine'] | 7,679,689 | [['D23.050.301.264.035', 'D23.101.100.110'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.022'], ['G04.152'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408.200.500'], ['G02.111.665', 'G02.607.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The efficacy of a novel compound, (e)-1-(4'-bromo-4-biphenylyl)-1-(4-chlorophenyl)-3-dimethylaminoprop-1-ene against Trypanosoma cruzi in mice. | The biological properties of a novel compound 353C with high activity against Trypanosoma cruzi, are described. The compound was about 10 times and 20 times more effective than either benznidazole or nifurtimox respectively, in producing radical cure in mice. 353C has a long half-life and showed anti-trypanosomal prope... | ['Animals', 'Biphenyl Compounds', 'Chagas Disease', 'Drug Evaluation, Preclinical', 'Mice', 'Nifurtimox', 'Nitroimidazoles', 'Trypanocidal Agents', 'Trypanosoma cruzi'] | 6,804,255 | [['B01.050'], ['D02.455.426.559.389.185'], ['C01.610.752.300.900.200', 'C01.920.625'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.640.600.480', 'D02.886.665.400', 'D03.383.312.649.480', 'D03.383.855.400'], ['D02.640.672', 'D03.383.129.308.658'], ['D27.505.954.122.250.100.875'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of red wine on oxidative stress and hypercholesterolemia induced by feeding a high-cholesterol diet in rat. | The effect of red wine on oxidative stress and hypercholesterolemia induced by feeding a high-cholesterol diet (supplemented with 1.65% of cholesterol (w/w) for 4 weeks) to female Wistar rats was examined. When red wine was simultaneously supplemented to high-cholesterol diet, total cholesterol, triglycerides, atheroge... | ['Animals', 'Bile Acids and Salts', 'Cholesterol, Dietary', 'Cholesterol, HDL', 'Female', 'Glutathione', 'Glutathione Peroxidase', 'Hypercholesterolemia', 'Lipid Peroxidation', 'Malondialdehyde', 'Oxidative Stress', 'Rats', 'Rats, Wistar', 'Steroid Hydroxylases', 'Superoxide Dismutase', 'Triglycerides', 'Wine'] | 15,957,244 | [['B01.050'], ['D04.210.500.105'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D12.644.456.448'], ['D08.811.682.732.500'], ['C18.452.584.500.500.396'], ['G02.111.515', 'G03.295.531.587'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
In vitro studies on cetamolol, a new potent cardioselective beta-adrenoceptor blocking agent with intrinsic sympathomimetic activity. | In vitro studies on the new beta-adrenoceptor antagonist, cetamolol (Betacor), have demonstrated that the compound is a potent antagonist of the chronotropic effects of isoproterenol on guinea pig atria. The pA2 value (8.05) of cetamolol was slightly lower than that of propranolol (8.44). The compound was shown to poss... | ['Acetamides', 'Adrenergic beta-Antagonists', 'Animals', 'Atenolol', 'Guinea Pigs', 'Male', 'Myocardial Contraction', 'Propranolol', 'Rats', 'Receptors, Adrenergic, beta'] | 6,139,156 | [['D02.065.064', 'D02.241.081.018.110'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['B01.050.150.900.649.313.992.550'], ['G09.330.580', 'G11.427.494.570'], ['D02.033.100.624.698.711', 'D02.033.755.624.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of de novo donor-specific anti-HLA antibodies in kidney graft failure: A case-control study. | The role of de novo donor-specific anti-human leukocyte antigen (anti-HLA) antibodies (dnDSA) within the pathways leading to graft failure remains not fully understood. We investigated 56 patients who were transplanted between 2002 and 2014 with kidney graft failure (cases), for a possible association of development of... | ['Adult', 'Antibodies', 'Biopsy', 'Case-Control Studies', 'Female', 'Graft Rejection', 'Graft Survival', 'HLA Antigens', 'Humans', 'Kidney', 'Kidney Transplantation', 'Logistic Models', 'Male', 'Multivariate Analysis', 'Proteinuria', 'Risk Factors', 'Tissue Donors', 'Treatment Outcome'] | 28,776,960 | [['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reflex bronchoconstriction induced by capsaicin in the dog. | To determine whether receptors stimulated by the injection of capsaicin into the pulmonary circulation cause reflex changes in airway size, six dogs were anesthetized with chloralose, paralyzed with succinylcholine, and mechanically ventilated (2 cm H2O PEEP). Intrapulmonary airways were outlined with tantalum dust, an... | ['Animals', 'Blood Pressure', 'Bronchi', 'Capsaicin', 'Denervation', 'Dogs', 'Fatty Acids, Unsaturated', 'Heart Rate', 'Stimulation, Chemical', 'Vagus Nerve'] | 511,721 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antisense RNA-mediated suppression of benzophenanthridine alkaloid biosynthesis in transgenic cell cultures of California poppy. | California poppy (Eschscholzia californica Cham.) cell cultures produce several benzophenanthridine alkaloids, such as sanguinarine, chelirubine, and macarpine, with potent pharmacological activity. Antisense constructs of genes encoding two enzymes involved in benzophenanthridine alkaloid biosynthesis, the berberine b... | ['Alkaloids', 'Amino Acids', 'Benzophenanthridines', 'Cells, Cultured', 'Cytochrome P-450 Enzyme System', 'Gene Expression', 'Isoquinolines', 'Isotope Labeling', 'Magnetic Resonance Spectroscopy', 'Mixed Function Oxygenases', 'Oxidoreductases, N-Demethylating', 'Papaver', 'Phenanthridines', 'Plant Extracts', 'Plant Pro... | 11,842,172 | [['D03.132'], ['D12.125'], ['D03.132.089', 'D03.633.300.633.207', 'D03.633.400.131'], ['A11.251'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G05.297'], ['D03.633.100.531'], ['E05.522'], ['E05.196.867.519'], ['D08.811.682.690.708'], ['D08.811.682.662.582'], ['B01.650.940.800.575.912.250.836.50... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Degradation of surfactant wastewater under microwave irradiation in the presence of activated carbon assisted with nano-sized TiO2 or nano-sized ZnO. | An improved method treating surfactant wastewater by the addition of semiconductor material such as nano-sized TiO2 or ZnO to activated carbon (AC) with microwave (MW) irradiation was proposed so as to assist efficient degradation of organic pollutants. A series of degradation experiments of sodium dodecyl benzene sulf... | ['Acids', 'Benzenesulfonates', 'Carbon', 'Catalysis', 'Charcoal', 'Chromatography, High Pressure Liquid', 'Chromatography, Ion Exchange', 'Microwaves', 'Nanoparticles', 'Particle Size', 'Solutions', 'Spectrophotometry, Ultraviolet', 'Surface-Active Agents', 'Time Factors', 'Titanium', 'Waste Disposal, Fluid', 'Water Pu... | 21,278,463 | [['D01.029'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['D01.268.150'], ['G02.130'], ['D01.268.150.150'], ['E05.196.181.400.300'], ['E05.196.181.400.383'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['J01.637.512.600'], ['G02.712'], ['D26.776'], ['E05.196.712.726.802',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
VEGF plasma level variations in duloxetine-treated patients with major depression. | BACKGROUND: The vascular endothelial growth factor (VEGF) signaling, which modulates angiogenesis and neurogenesis within the neurovascular unit, might play an important role in the neuro-endocrine-immune (NEI) stress-adaptation system. Recent evidence suggests that VEGF is involved in the pathophysiology of a number o... | ['Adult', 'Antidepressive Agents', 'Depressive Disorder, Major', 'Duloxetine Hydrochloride', 'Female', 'Humans', 'Male', 'Middle Aged', 'Thiophenes', 'Vascular Endothelial Growth Factor A'] | 23,871,390 | [['M01.060.116'], ['D27.505.954.427.700.122'], ['F03.600.300.375'], ['D02.886.778.260', 'D03.383.903.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.886.778', 'D03.383.903'], ['D12.644.276.100.800.200', 'D12.776.467.100.800.200', 'D23.529.100.800.200']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Four New 2-(2-Phenylethyl)-4H-chromen-4-one Derivatives from the Resinous Wood of Aquilaria sinensis and Their Inhibitory Activities on Neutrophil Pro-Inflammatory Responses. | Four new 2-(2-phenylethyl)-4H-chromen-4-one derivatives, 6-hydroxy-5-methoxy-2-[2-(4'-methoxyphenyl)ethyl]chromone (1: ), 6,7-dimethoxy-2-[2-(2'-hydroxyphenyl)ethyl]chromone (2: ), 5-hydroxy-6-methoxy-2-[2-(3'-methoxyphenyl)ethyl]-chromone (3: ), and 7-chloro-8-hydroxy-2-[2-(4'-methoxyphenyl)ethyl]chromone (4: ), have ... | ['Adult', 'Anti-Inflammatory Agents, Non-Steroidal', 'Chromones', 'Drug Evaluation, Preclinical', 'Humans', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Neutrophils', 'Resins, Plant', 'Thymelaeaceae'] | 29,954,026 | [['M01.060.116'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['A11.118.637.415.583', 'A11.627.340.583'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies. | PU-H71 is a purine-scaffold Hsp90 inhibitor that, in contrast to other Hsp90 inhibitors, displays unique selectivity for binding the fraction of Hsp90 that is preferentially associated with oncogenic client proteins and enriched in tumor cells (teHsp90). This property allows PU-H71 to potently suppress teHsp90 without ... | ['Animals', 'Apoptosis', 'Autophagy', 'Benzodioxoles', 'Cell Line, Tumor', 'Cell Proliferation', 'Gammaherpesvirinae', 'HSP90 Heat-Shock Proteins', 'Herpesviridae Infections', 'Humans', 'Mice', 'NF-kappa B', 'Neoplasm Transplantation', 'Neoplasms', 'Proteome', 'Proteomics', 'Purines', 'Signal Transduction', 'Viral Prot... | 23,943,653 | [['B01.050'], ['G04.146.954.035'], ['G04.011'], ['D03.383.246.118', 'D03.633.100.115'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['B04.280.210.400', 'B04.280.382.400', 'B04.613.204.500'], ['D12.776.580.216.380'], ['C01.925.256.466'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Challenges in herbal research: a randomized clinical trial to assess blinding with ginger. | OBJECTIVE: To assess methods to blind study participants to encapsulated ginger (Zingiber officinale).DESIGN: A randomized double-blind placebo controlled trial.SUBJECTS: Eighty healthy male and female volunteers.OUTCOME MEASURES: Whether participants can accurately determine if they receive a ginger or placebo capsule... | ['Adult', 'Double-Blind Method', 'Female', 'Ginger', 'Humans', 'Male', 'Placebos', 'Plant Preparations'] | 16,036,167 | [['M01.060.116'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.650.940.800.575.912.250.618.937.900.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.660', 'E02.785'], ['D20.215.784']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The mutual interplay between calcification and coccolithovirus infection. | Two prominent characteristics of marine coccolithophores are their secretion of coccoliths and their susceptibility to infection by coccolithoviruses (EhVs), both of which display variation among cells in culture and in natural populations. We examined the impact of calcification on infection by challenging a variety o... | ['Calcinosis', 'Haptophyta', 'Host-Pathogen Interactions', 'Phycodnaviridae', 'Plant Diseases'] | 30,043,404 | [['C18.452.174.130'], ['B01.400'], ['G06.462', 'G16.527.200'], ['B04.280.600', 'B04.715.600'], ['G15.610']] | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Odontoid process and clival regeneration with Chiari malformation worsening after transoral decompression: an unexpected and previously unreported cause of "accordion phenomenon". | PURPOSE: Transoral odontoidectomy followed by occipito-cervical fixation is a widely used approach to relieve ventral compressions at the craniovertebral junction (CVJ). Despite the large amount of literature on this approach and its complications, no previous reports of odontoid process and clival regeneration followi... | ['Arnold-Chiari Malformation', 'Bone Regeneration', 'Child', 'Cranial Fossa, Posterior', 'Decompression, Surgical', 'Humans', 'Male', 'Odontoid Process', 'Orthopedic Procedures', 'Recurrence', 'Spinal Cord Compression'] | 25,519,842 | [['C10.500.680.291', 'C16.131.666.680.291'], ['G11.427.213.140', 'G16.762.150.150'], ['M01.060.406'], ['A01.456.830.200', 'A02.835.232.781.750.400'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.151.383.668'], ['E02.718', 'E04.555'], ['C23.550.291.937'], ['C10.228.854.761', 'C26.819.6... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Retinal bioelectrical activity in amblyopia]. | The mechanisms of visual dysfunction in high amblyopia have not been adequately investigated. Different types of electroretinograms (ERG) as part of the ISCEV standard, as well as macular (15%) pattern and multifocal ERG were recorded in 41 children aged 5-17 years who had high amblyopia with varying gaze fixation and ... | ['Adolescent', 'Amblyopia', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Electroretinography', 'Humans', 'Retina', 'Visual Acuity'] | 18,756,798 | [['M01.060.057'], ['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['E01.370.380.225', 'E01.370.405.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.729'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bilateral macular lesions in a 10-year-old girl. | PURPOSE: To report a previously undescribed macular dystrophy.DESIGN: Single descriptive case report.METHODS: Presentation of clinical findings, including ophthalmoscopy, fluorescein angiography, full-field and multifocal electroretinography (ERG), optical coherence tomography (OCT), and visual fields.RESULTS: A 10 yea... | ['Child', 'Electroretinography', 'Female', 'Fluorescein Angiography', 'Functional Laterality', 'Humans', 'Macular Degeneration', 'Ophthalmoscopy', 'Tomography, Optical Coherence', 'Visual Acuity', 'Visual Fields'] | 17,188,069 | [['M01.060.406'], ['E01.370.380.225', 'E01.370.405.270'], ['E01.370.370.050.350', 'E01.370.380.250'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439'], ['E01.370.380.560'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', 'E05.642.249.500'], ['E01.370.38... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Is health care infected by Baumol's cost disease? Test of a new model. | Rising health care costs are a policy concern across the Organisation for Economic Co-operation and Development, and relatively little consensus exists concerning their causes. One explanation that has received revived attention is Baumol's cost disease (BCD). However, developing a theoretically appropriate test of BCD... | ['Adult', 'Cost of Illness', 'Delivery of Health Care', 'Efficiency', 'Female', 'Health Care Costs', 'Health Care Sector', 'Humans', 'Male', 'Middle Aged', 'Models, Econometric', 'Organisation for Economic Co-Operation and Development', 'United States', 'Young Adult'] | 29,423,941 | [['M01.060.116'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['N04.590.374', 'N05.300'], ['F02.784.692.351', 'N04.452.209'], ['N03.219.151.400', 'N05.300.375'], ['J01.576.489', 'N03.219.650'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Pre-operative factors influencing post-operative outcomes from MyoRing implantation in keratoconus. | BACKGROUND: To identify pre-operative factors that influence post-operative performance of a full-ring intra-corneal implant (MyoRing) for the management of keratoconus.METHOD: In a retrospective study, medical records of 70 keratoconus eyes of 70 consecutive surgical patients with a mean age of 28.54 ± 6.52 years, who... | ['Adult', 'Corneal Stroma', 'Female', 'Humans', 'Keratoconus', 'Male', 'Middle Aged', 'Postoperative Period', 'Preoperative Period', 'Prostheses and Implants', 'Prosthesis Implantation', 'Refraction, Ocular', 'Retrospective Studies', 'Treatment Outcome', 'Visual Acuity', 'Young Adult'] | 30,536,629 | [['M01.060.116'], ['A09.371.060.217.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.204.627'], ['M01.060.116.630'], ['E04.614.750', 'N02.421.585.753.750'], ['E04.614.937', 'N02.421.585.753.937'], ['E07.695'], ['E04.650'], ['E01.370.380.850.700', 'G01.590.775', 'G14.760'], ['E05.318.372.500.500.500', 'E05.... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dissolved oxygen regulation by logarithmic/antilogarithmic control to improve a wastewater treatment process. | This paper presents the automation of a real activated sludge wastewater treatment plant, which is located at San Antonio Ajijic in Jalisco, Mexico. The main objective is to create an on-line automatic supervision system, and to regulate the dissolved oxygen concentration in order to improve the performances of the pro... | ['Algorithms', 'Bacteria, Aerobic', 'Computer Simulation', 'Feedback, Physiological', 'Fuzzy Logic', 'Models, Biological', 'Numerical Analysis, Computer-Assisted', 'Online Systems', 'Oxygen', 'Sewage', 'Waste Water', 'Water Pollutants, Chemical', 'Water Purification'] | 24,617,069 | [['G17.035', 'L01.224.050'], ['B03.120'], ['L01.224.160'], ['G07.410.732'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['E05.599.395'], ['L01.224.680.700'], ['L01.313.500.750.300.742'], ['D01.268.185.550', 'D01.362.670'], ['D20.944.932.500'], ['D20.944.932', 'N06.850.460.710.865'], ['D27.888.284.903.655... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Radioactive seed localization breast biopsy and lumpectomy: can specimen radiographs be eliminated? | BACKGROUND: Wire localization (WL) is the current standard for surgical diagnosis of nonpalpable breast lesions. Many disadvantages inherent to WL are solved with radioactive seed localization (RSL). This trial investigated the ability of RSL to reduce the need for specimen radiographs and operating room delays associa... | ['Adult', 'Biopsy', 'Brachytherapy', 'Breast Neoplasms', 'Calcinosis', 'Diagnosis, Differential', 'Female', 'Humans', 'Iodine Radioisotopes', 'Mammography', 'Mastectomy, Segmental', 'Sensitivity and Specificity', 'Titanium'] | 14,597,442 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E02.815.150'], ['C04.588.180', 'C17.800.090.500'], ['C18.452.174.130'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enterovirus is not present in placentas from cases of perinatal depression using polymerase chain reaction analysis. | Enteroviruses have been implicated as a cause of low Apgar scores in conjunction with perinatal seizures and respiratory insufficiency. Using in-situ reverse transcriptase polymerase chain reaction (in-situ PCR), Nuovo et al detected enterovirus in up to 86% of placentas from perinates exhibiting these symptoms. In-sit... | ['Adult', 'Apgar Score', 'Enterovirus', 'Enterovirus Infections', 'Female', 'Humans', 'Hypoxia, Brain', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Placenta', 'Polymerase Chain Reaction', 'Pregnancy', 'RNA, Viral', 'Respiratory Insufficiency', 'Young Adult'] | 18,808,215 | [['M01.060.116'], ['E01.370.600.050'], ['B04.820.578.750.284'], ['C01.925.782.687.359'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.624', 'C23.888.852.079.797'], ['M01.060.703.520'], ['C16.614'], ['A16.710'], ['E05.393.620.500'], ['G08.686.784.769'], ['D13.444.735.828'], ['C08.618.846'], ['M01.060.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Medical staff contracting: contract terms and the negotiation process. | This article--the second in a series analyzing the physician-hospital contracting process from the physician's perspective--addresses negotiation of specific contract terms, including such controversial issues as exclusive contracts, mandatory managed care arrangements, and tie-in of contract terms and medical staff pr... | ['Contract Services', 'Decision Making', 'Goals', 'Hospital Administration', 'Medical Staff, Hospital', 'Negotiating', 'Organizational Objectives', 'United States'] | 10,124,487 | [['N03.219.463.100'], ['F02.463.785.373'], ['F01.658.500'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['M01.526.485.630.490', 'M01.526.485.740.422', 'N02.360.630.490', 'N02.360.740.422'], ['F01.145.209.520', 'F01.829.401.520', 'F02.463.785.373.520', 'L01.143.620', 'N04.452.677.430'], ['N04.452.615'], ['Z01.107... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Effect of artificial urinary sphincter implantation on erectile function and sexual satisfaction. | Artificial urinary sphincter (AUS) implantation is the gold standard treatment in total stress urinary incontinence (SIU). Our aim is to evaluate the effect of AUS implantation on erectile function and sexual satisfaction (SS). Fourteen patients aged 58-73 years (mean: 66.92 ± 4.51 years) who underwent AUS implantation... | ['Aged', 'Erectile Dysfunction', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Orgasm', 'Patient Satisfaction', 'Penile Erection', 'Prostatectomy', 'Prosthesis Implantation', 'Treatment Outcome', 'Urinary Incontinence, Stress', 'Urinary Sphincter, Artificial'] | 30,995,702 | [['M01.060.116.100'], ['C12.294.644.486', 'F03.835.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.686.784.460'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.8... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Whole-body vibration training improves the balance ability and leg strength of athletic throwers. | BACKGROUND: Physical strength improvements have been observed with whole-body vibration training (WBVT); however, the appropriate load and duration have not been determined. Furthermore, studies on WBVT in throwing athletes, for whom power training is important, are lacking. Therefore, we examined the effectiveness of ... | ['Adult', 'Case-Control Studies', 'Exercise Test', 'Humans', 'Leg', 'Male', 'Muscle Strength', 'Muscle, Skeletal', 'Track and Field', 'Vibration', 'Young Adult'] | 30,317,837 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['E01.370.600.425', 'G11.427.560'], ['A02.633.567', 'A10.690.552.500'], ['I03.450.642.845.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Low-dose, once-daily, intraclot injections of alteplase for treatment of acute deep venous thrombosis. | PURPOSE: To evaluate the safety and efficacy of once-daily intraclot injections of low doses (? 10 mg) of tissue plasminogen activator (tPA) for thrombolysis of venous thrombosis.MATERIALS AND METHODS: In prospective studies, 33 patients with subclavian, jugular, and central venous thrombosis (SJ-CVT) (all but two case... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Female', 'Fibrinolytic Agents', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Tissue Plasminogen Activator', 'Treatment Outcome', 'Vascular Patency', 'Venous Thrombosis'] | 21,664,144 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['D08.811.2... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells. | Tumor angiogenesis is necessary for solid tumor progression and metastasis. Cyclooxygenase (COX)-2 is known to play an important role in cancer growth and invasion, and it activates the signaling pathways controlling cell proliferation, migration, apoptosis, and angiogenesis. COX-2 is reported to be expressed in many c... | ['Animals', 'Blotting, Western', 'Cell Movement', 'Cell Proliferation', 'Cells, Cultured', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Endothelium, Vascular', 'Female', 'Humans', 'Melanoma', 'Mice', 'Mice, Nude', 'Mouth Neoplasms', 'Neovascularization, Pathologic', 'Nitrobenzenes', 'RNA, Messenger', 'Real-Time ... | 21,384,343 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D08.811.600.720.750'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function. | Insulin-like growth factor-I (IGF-I) and IGF-II have powerful, well defined effects on osteoblastic cells, stimulating their proliferation and inducing collagen synthesis, but the role of IGF-I and -II in modulating osteoclast differentiation and activity remains unclear. We first examined the bone-resorptive effects o... | ['Acid Phosphatase', 'Animals', 'Antibodies, Monoclonal', 'Bone Marrow Cells', 'Bone Resorption', 'Cell Division', 'Cells, Cultured', 'Humans', 'Insulin-Like Growth Factor I', 'Insulin-Like Growth Factor II', 'Mice', 'Osteoblasts', 'Osteoclasts', 'Rats', 'Receptors, Somatomedin', 'Skull', 'beta-Galactosidase'] | 7,828,521 | [['D08.811.277.352.650.025'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.148', 'A15.378.316'], ['C05.116.264', 'G11.427.213.150'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['B01.050.150.900.649.313.988.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical observation on monovision of cataract surgery with different near addition]. | Objective: To observe the influence on spectacle independence, satisfaction and visual function after cataract surgery monovision with different ADD. Methods: Prospective clinical study. All patients were collected from the department of ophthalmology, Shanghai JiaoTong University Affiliated Sixth People's Hospital who... | ['Aged', 'Chi-Square Distribution', 'China', 'Eyeglasses', 'Female', 'Humans', 'Lens Implantation, Intraocular', 'Lenses, Intraocular', 'Life Style', 'Male', 'Middle Aged', 'Myopia', 'Patient Satisfaction', 'Phacoemulsification', 'Postoperative Period', 'Prospective Studies', 'Sex Distribution', 'Surveys and Questionna... | 28,606,268 | [['M01.060.116.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['Z01.252.474.164'], ['E07.632.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.540.825.600'], ['E07.632.500.460', 'E07.695.460'], ['F01.829.458'], ['M01.060.116.630'], ['C11.744.636'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Complement activation by surface modified poly(methyl methacrylate) intraocular lenses. | The complement activation potential of surface modified (passivated) poly(methyl methacrylate) (PMMA) intraocular lenses (IOLs) with polypropylene loops was compared to that of standard PMMA IOLs with polypropylene loops. Both lens types were incubated in human sera for six hours and then the C3a and C5a levels were me... | ['Complement Activation', 'Complement C3a', 'Complement C5a', 'Humans', 'Lenses, Intraocular', 'Methylmethacrylates', 'Radioimmunoassay', 'Surface Properties'] | 2,040,970 | [['G12.274'], ['D12.776.124.486.274.024.250', 'D12.776.124.486.274.250.250'], ['D12.776.124.486.274.024.270', 'D12.776.124.486.274.450.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.500.460', 'E07.695.460'], ['D02.241.081.069.800.550', 'D05.750.716.822.111.650.605', 'D25.720.716.822.111.650.605', 'J0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Stress-induced expression of the Escherichia coli phage shock protein operon is dependent on sigma 54 and modulated by positive and negative feedback mechanisms. | The phage shock protein (psp) operon of Escherichia coli is strongly induced in response to heat, ethanol, osmotic shock, and infection by filamentous bacteriophages. The operon contains at least four genes--pspA, pspB, pspC, and pspE--and is regulated at the transcriptional level. We report here that psp expression is... | ['Bacterial Proteins', 'Base Sequence', 'Chromosome Deletion', 'Chromosomes, Bacterial', 'Coliphages', 'Escherichia coli', 'Escherichia coli Proteins', 'Feedback', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Genotype', 'Heat-Shock Proteins', 'Models, Genetic', 'Molecular Sequence Data', 'Operon', 'Pla... | 1,717,346 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['B04.123.205'], ['B03.440.450.425.325.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cholera control in an inaccessible district in Tanzania: importance of temporary rural centres. | The fourth ever recorded outbreak of cholera on Tanzania mainland started on 2.10.77 in Twasalie village which is a delta island in the Utete district on the Indian Ocean coastal line. Poor communication and inadequate health facilities in the district delayed detection and reporting of the outbreak for four weeks lead... | ['Cholera', 'Community Health Centers', 'Disease Outbreaks', 'Health Facilities', 'Humans', 'Immunization', 'Medically Underserved Area', 'Quarantine', 'Rural Health', 'Socioeconomic Factors', 'Tanzania', 'Workforce', 'Zambia'] | 7,269,798 | [['C01.150.252.400.959.347'], ['N02.278.035.128'], ['N06.850.290'], ['N02.278'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['N03.349.650.340', 'N05.300.450.520'], ['N06.850.780.200.725'], ['N01.400.548.75... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Differential modulation of host macrophage function by AK-5 tumor is dependent on the site of tumor transplantation. | We have studied the mechanisms involved in the activation or suppression of the immune response by the tumor cells, which is also dependent on the site of tumor transplantation. AK-5 tumor cells when transplanted s.c. activated peritoneal macrophages through the induction of different cytokines, whereas tumor cells whe... | ['Animals', 'Antigens, Neoplasm', 'Coculture Techniques', 'Cytokines', 'Macrophages', 'Neoplasm Transplantation', 'Neoplasms, Experimental', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Peroxynitrous Acid', 'Rats', 'Rats, Wistar', 'Reactive Oxygen Species', 'Tumor Cells, Cultured', 'Tyrosine'] | 12,036,600 | [['B01.050'], ['D23.050.285'], ['E05.481.500.374'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['E05.624'], ['C04.619', 'E05.598.500.496'], ['D08.811.682.664.500.772'], ['D08.811.682.664.500.772.500', 'D12.776.157.687.575',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy. | Adoptive cell therapy using tumor-reactive T lymphocytes is a promising approach for treating advanced cancer. Successful tumor eradication depends primarily on the expansion and survival of the adoptively transferred T cells. Lymphodepletion using total body irradiation (TBI) and administering high-dose interleukin (I... | ['Animals', 'CD8-Positive T-Lymphocytes', 'Cancer Vaccines', 'Immunotherapy, Adoptive', 'Interleukin-2', 'Lymphocyte Depletion', 'Melanoma, Experimental', 'Mice', 'Mice, Inbred C57BL', 'Programmed Cell Death 1 Receptor', 'Vaccines, Subunit'] | 22,367,213 | [['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D20.215.894.200'], ['E02.095.465.425.400.330.050.400', 'E05.478.550.520.050.400'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-resolution frequency tuning but not temporal coding in the human cochlea. | Frequency tuning and phase-locking are two fundamental properties generated in the cochlea, enabling but also limiting the coding of sounds by the auditory nerve (AN). In humans, these limits are unknown, but high resolution has been postulated for both properties. Electrophysiological recordings from the AN of normal-... | ['Acoustic Stimulation', 'Adult', 'Animals', 'Cochlea', 'Cochlear Nerve', 'Female', 'Healthy Volunteers', 'Hearing', 'Humans', 'Macaca mulatta', 'Male', 'Sound', 'Young Adult'] | 30,321,166 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['B01.050'], ['A09.246.300.246'], ['A08.800.800.120.910.120'], ['M01.774.500', 'M01.955.236'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tumor progression and cellular differentiation of pulmonary adenocarcinomas in SV40 large T antigen transgenic mice. | Transgenic mice harboring the SV40 early region genes under transcriptional control of regulatory regions from the human surfactant protein C (SP-C) gene were used to study the progression of pulmonary adenocarcinomas in vivo. SP-C/SV40 early region gene (SP-C/TAg) transgenic mice consistently developed pulmonary adeno... | ['Adenocarcinoma', 'Animals', 'Antigens, Polyomavirus Transforming', 'CDC2 Protein Kinase', 'Cell Differentiation', 'Enzyme Inhibitors', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'Male', 'Mice', 'Mice, Nude', 'Mice, Transgenic', 'Promoter Regions, Genetic', 'Proteins', 'Proteolipid... | 9,191,473 | [['C04.557.470.200.025'], ['B01.050'], ['D12.776.624.664.520.090', 'D12.776.964.700.090', 'D23.050.285.062.090', 'D23.050.327.062.090'], ['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.77... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of cell-matrix interactions in osteoclast differentiation. | Osteoclast and their mononuclear cell precursors are present within the bone microenvironment at sites of physiologic and pathologic bone resorption. Analysis of tissues from sites of bone resorption reveal that cells expressing the full morphological and functional properties of mature osteoclasts are restricted to th... | ['Animals', 'Bone Matrix', 'Bone Resorption', 'Bone and Bones', 'Cell Adhesion Molecules', 'Cell Differentiation', 'Humans', 'Integrins', 'Macrophage Colony-Stimulating Factor', 'Macrophages', 'Mice', 'Osteoblasts', 'Osteoclasts'] | 17,966,395 | [['B01.050'], ['A10.165.265.166'], ['C05.116.264', 'G11.427.213.150'], ['A02.835.232', 'A10.165.265'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['G04.152'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408'], ['D12.644.276.374.410.240.500', 'D12.776.395.240.500', 'D12... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Foreign intervention in medical education: a case study of the Rockefeller Foundation's involvement in a Thai medical school. | A case study of the process of foreign intervention in medical education in the developing world is presented. Material collected from the Rockefeller Foundation Archives on a Foundation program in Thailand is used to analyze the conditions under which foreign agencies and their personnel intervene in the development o... | ['Community Health Services', 'Culture', 'Delivery of Health Care', 'Developing Countries', 'Education, Medical', 'Foreign Professional Personnel', 'Foundations', 'Humans', 'Models, Theoretical', 'Quality of Health Care', 'Thailand'] | 939,621 | [['N02.421.143'], ['I01.076.201.450', 'I01.880.853.100'], ['N04.590.374', 'N05.300'], ['I01.615.500.300'], ['I02.358.399'], ['M01.526.407'], ['N03.219.483.311', 'N03.540.630.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['N04.761', 'N05.715'], ['Z01.252.145.841']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Occurrence of ethanol and other drugs in blood and urine specimens from female victims of alleged sexual assault. | Results of toxicological analysis of blood and urine specimens from 1806 female victims of alleged non-consensual sexual activity are reported. After making contact with the police authorities, the victims were examined by a physician for injuries and biological specimens were taken for forensic toxicology and other pu... | ['Adolescent', 'Adult', 'Central Nervous System Depressants', 'Crime Victims', 'Ethanol', 'Female', 'Forensic Toxicology', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Illicit Drugs', 'Narcotics', 'Pharmaceutical Preparations', 'Rape', 'Seasons', 'Substance Abuse Detection', 'Sweden'] | 18,922,656 | [['M01.060.057'], ['M01.060.116'], ['D27.505.696.277', 'D27.505.954.427.210'], ['M01.135'], ['D02.033.375'], ['H01.158.891.424', 'H02.884.424', 'I01.198.780.968'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['D27.505.696.277.600', 'D27.505.696.663.850.014.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Metals in tissues of seabass and seabream reared in sites with oxic and anoxic substrata and risk assessment for consumers. | Twenty-eight metals and elements were measured in the muscle, liver, gills, bone and intestine of farmed seabass and gilthead seabream from four Mediterranean fish farms. The influence of fish species and the effect of environmental conditions on the metal accumulation in fish tissues was investigated. Most concentrati... | ['Animals', 'Bass', 'Heavy Metal Poisoning', 'Humans', 'Metals', 'Organ Specificity', 'Poisoning', 'Risk Assessment', 'Sea Bream', 'Seafood'] | 26,471,605 | [['B01.050'], ['B01.050.150.900.493.602.105'], ['C25.723.522'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.552'], ['G07.650'], ['C25.723'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['B01.050.150.900.493.602.750'], ['G07.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Randomized Controlled Trials in Implant Dentistry: Assessment of the Last 20 Years of Contribution and Research Network Analysis. | The aim of this study was to evaluate the characteristics of randomized controlled trials (RCTs) regarding implant-supported single tooth or fixed partial dentures. We performed searches (PubMed/MEDLINE and Web of Science) to identify all RCTs published from 1996 to 2016 and assessed publication details, study characte... | ['Dental Implantation, Endosseous', 'Dental Implants', 'Dentistry', 'Humans', 'Network Meta-Analysis', 'Randomized Controlled Trials as Topic'] | 31,216,256 | [['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314.310'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06', 'H02.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500.500', 'E05.581.500.501.500', 'N05.715.360.325.515.500', 'N06.850.520.445... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Determinants of operative mortality in valvular heart surgery. | OBJECTIVE: In some respects, outcome reporting in valvular surgery has been hampered by focusing on specific populations, reluctance to publish high-risk subgroups, and possibly skewed or inadequate samples. The goal of this study was to evaluate risk factors for operative mortality comprehensively across the entire sp... | ['Aged', 'Cardiac Surgical Procedures', 'Female', 'Heart Valve Diseases', 'Humans', 'Male', 'Postoperative Complications', 'Risk Assessment', 'Risk Factors'] | 16,515,904 | [['M01.060.116.100'], ['E04.100.376', 'E04.928.220'], ['C14.280.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
N-linked glycosylation is an important parameter for optimal selection of cell lines producing biopharmaceutical human IgG. | We studied the variations in N-linked glycosylation of human IgG molecules derived from 105 different stable cell lines each expressing one of the six different antibodies. Antibody expression was based on glutamine synthetase selection technology in suspension growing CHO-K1SV cells. The glycans detected on the Fc fra... | ['Animals', 'CHO Cells', 'Cell Line', 'Cricetinae', 'Cricetulus', 'Glycosylation', 'Humans', 'Immunoglobulin G', 'Polysaccharides'] | 19,224,598 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.11... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Removal of red light minimizes methylene blue-stimulated DNA damage in oesophageal cells: implications for chromoendoscopy. | Barrett's oesophagus (BO) carries an increased risk of progression to oesophageal adenocarcinoma. Chromoendoscopy with methylene blue (MB) can be used to facilitate identification of BO and target areas for biopsy. If photoexcited, MB can generate reactive oxygen species and genotoxic photodegradation products leading ... | ['Analysis of Variance', 'Apoptosis', 'Barrett Esophagus', 'Cell Line, Tumor', 'Comet Assay', 'DNA Damage', 'Endoscopy, Digestive System', 'Humans', 'Light', 'Methylene Blue', 'Reactive Oxygen Species', 'Tetrazolium Salts', 'Thiazoles'] | 19,218,330 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G04.146.954.035'], ['C04.834.154', 'C06.405.117.102'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['E01.370.372.250', 'E01.370.388.250.250', 'E04.210.240'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
False detection of left atrial thrombus by the angiographic sign of "neovascularity". | "Neovascularity" in the region of the left atrial appendage was demonstrated by coronary arteriography preoperatively in five patients with mitral valve disease and was attributed to the presence of thrombus in the left atrium. Subsequently, they underwent surgery, but thorough inspection of the left atrium did not rev... | ['Adult', 'Calcinosis', 'Cardiac Catheterization', 'Coronary Angiography', 'Diagnosis, Differential', 'Heart Atria', 'Humans', 'Middle Aged', 'Mitral Valve Insufficiency', 'Mitral Valve Stenosis', 'Neovascularization, Pathologic', 'Rheumatic Heart Disease', 'Thrombosis'] | 2,480,185 | [['M01.060.116'], ['C18.452.174.130'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E01.171'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.484.461'], ['C14.2... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Mouse Model of Furosemide-Induced Overactive Bladder. | Detailed in this unit is a mouse model of overactive bladder and urinary incontinence based on diuretic stress-induced urination. The procedure involves the use of a unique, highly sensitive, and automated urine capturing method to measure urinary latency, frequency, and void volume. Although this method was first desc... | ['Animals', 'Disease Models, Animal', 'Furosemide', 'Male', 'Mice', 'Muscarinic Antagonists', 'Urinary Bladder', 'Urinary Bladder, Overactive', 'Urinary Incontinence', 'Urination'] | 27,636,110 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.505.519.625.120.200.500', 'D27.505.696.577.120.200.500'], ['A05.810.890'], ['C12.777.829.866', 'C13.351.968.829.813', 'C23.888.942.34... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of thiamine diphosphate in pyruvate decarboxylase from Zymomonas mobilis. | Replacement of tryptophan 392 located in the active site cavity of pyruvate decarboxylase (PDC; EC 4.1.1.1) from Zymomonas mobilis by methionine or glutamine yields enzymes with smaller catalytic constants of 8.5 s(-1) and 3.6 s(-1) at 4 degrees C, compared to that of the wild-type enzyme (17 s(-1)). The rate constants... | ['Hydrogen-Ion Concentration', 'Kinetics', 'Mutation', 'Protons', 'Pyruvate Decarboxylase', 'Thiamine Pyrophosphate', 'Zymomonas'] | 9,891,980 | [['G02.300'], ['G01.374.661', 'G02.111.490'], ['G05.365.590'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D08.811.520.224.125.750'], ['D02.886.675.900.702', 'D03.383.129.708.900.702', 'D03.383.742.795.702', 'D08.211.878'], ['B03.440.450.980', 'B03.660.050.800.990']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of platelet activating factor isolated from rabbit basophils as acetyl glyceryl ether phosphorylcholine. | Platelet activating factor obtained from antigen-stimulated rabbit buffy coat leukocytes containing 10% IgE-sensitized basophils was shown by gas-liquid chromatographic and mass spectrometric analysis of products after acetolysis and by base and acid hydrolysis to be acetyl-alkylglyceryl phosphorylcholine. The alkyl si... | ['Animals', 'Basophils', 'Chromatography, Gas', 'Immunoglobulin E', 'Lysophosphatidylcholines', 'Mass Spectrometry', 'Platelet Activating Factor', 'Rabbits'] | 7,380,824 | [['B01.050'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['E05.196.181.349'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['D10.570.755.375.760.550.550'], ['E05.196.566'], ['D02.033.100.291.211.500', 'D02.0... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mesenchymal tumors of the uterus. V. Intravenous leiomyomatosis. A clinical and pathologic study of 14 cases. | Fourteen examples of intravenous leiomyomatosis in the FIP files were studied. Growth beyond the uterus occurred in 10 of the 14 examples, largely in vessels in the broad ligament and in uterine and iliac veins. Metastasis to the heart occurred in 1 example. The study provides evidence that is consistent with both theo... | ['Adult', 'Aged', 'Castration', 'Diagnosis, Differential', 'Fallopian Tubes', 'Female', 'Humans', 'Hysterectomy', 'Leiomyoma', 'Leiomyosarcoma', 'Middle Aged', 'Neoplasm Metastasis', 'Pregnancy', 'Uterine Neoplasms', 'Uterus', 'Veins'] | 1,203,870 | [['M01.060.116'], ['M01.060.116.100'], ['E04.270.282', 'E04.950.165'], ['E01.171'], ['A05.360.319.114.373', 'A13.706.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['C04.557.450.590.450'], ['C04.557.450.590.455', 'C04.557.450.795.455'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A preliminary study of the effect of pyridoxine administration in a subgroup of hyperkinetic children: a double-blind crossover comparison with methylphenidate. | A small sample of six patients with the putative "hyperkinetic syndrome" participated in a research protocol comparing administration of pyridoxine, methylphenidate, and placeboes. The children had had low whole blood serotonin levels and a history of previous responsiveness to methylphenidate. The results of the doubl... | ['Adolescent', 'Child', 'Double-Blind Method', 'Female', 'Humans', 'Hyperkinesis', 'Male', 'Methylphenidate', 'Motor Activity', 'Pyridoxal Phosphate', 'Pyridoxine', 'Serotonin'] | 497,303 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cycloheximide rapidly inhibits cortical COX activity and COX-dependent pial arteriolar dilation in piglets. | We have previously shown that cycloheximide (CHX) preserved neuronal function after global cerebral ischemia in piglets, in a manner similar to indomethacin. To elucidate the mechanism of this protection, we tested the hypothesis that CHX would inhibit cyclooxygenase (COX) activity in the piglet cerebral cortex and vas... | ['Animals', 'Animals, Newborn', 'Arachidonic Acid', 'Cerebral Cortex', 'Cerebrovascular Circulation', 'Cycloheximide', 'Dinoprost', 'Epoprostenol', 'Prostaglandin-Endoperoxide Synthases', 'Protein Synthesis Inhibitors', 'Swine', 'Vasodilation'] | 10,484,435 | [['B01.050'], ['B01.050.050.282'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['A08.186.211.200.885.287.500'], ['G09.330.100.159'], ['D03.383.621.808.240'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['D08.811.600.720', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation between levels of sulcular and capillary blood glucose. | AIM: The aim of this study was to evaluate the correlation between capillary blood glucose levels (CBGLs) and sulcular blood glucose levels (SBGLs) using blood obtained from gingival tissue during routine periodontal examinations to determine if sulcular blood samples can be used as a non-invasive means to diagnosis bl... | ['Adult', 'Blood Glucose', 'Capillaries', 'Diabetes Complications', 'Female', 'Gingival Crevicular Fluid', 'Gingival Hemorrhage', 'Glucose', 'Humans', 'Male', 'Periodontal Pocket', 'Periodontitis'] | 19,279,967 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['A07.015.461.165'], ['C19.246.099'], ['A12.383.500'], ['C07.465.625.446', 'C07.465.714.258.250', 'C23.550.414.922.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465.714.533.750'], ['C07.465.714.533']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Using DRGs and standard costs to control nursing labor costs. | Nursing care is a very significant part of a healthcare organization's costs. However, until recently, methods of controlling nursing costs were largely ineffective. With the implementation of the prospective payment system and the use of diagnosis related groups, budgeting and controlling nursing costs are now possibl... | ['Accounting', 'Analysis of Variance', 'Budgets', 'Cost Control', 'Costs and Cost Analysis', 'Diagnosis-Related Groups', 'Length of Stay', 'Nursing Service, Hospital', 'Personnel Management', 'Personnel Staffing and Scheduling', 'United States'] | 10,312,677 | [['N03.219.463.030'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['N03.219.463.060'], ['N03.219.151.160'], ['N03.219.151'], ['N03.219.521.710.305.200.080'], ['E02.760.400.480', 'N02.421.585.400.480'], ['N02.278.216.500.968.489', 'N02.421.539.180', 'N04.452.442.452.422.489'], ['N04.452.677'], ['I... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Heterodimerization of human orexin receptor 1 and kappa opioid receptor promotes protein kinase A/cAMP-response element binding protein signaling via a Gás-mediated mechanism. | Orexin and dynorphin are co-expressed in the same synaptic vesicles of hypothalamic neurons and play opposing roles in cocaine self-administration, brain stimulation reward, and impulsivity in ventral tegmental area (VTA), where dopamine neurons express both OX1R and KORs. However, detailed mechanisms of how the corele... | ['Animals', 'Calcium', 'Cyclic AMP', 'Cyclic AMP Response Element-Binding Protein', 'Cyclic AMP-Dependent Protein Kinases', 'Dimerization', 'Fluorescence Resonance Energy Transfer', 'GTP-Binding Protein alpha Subunits, Gq-G11', 'HEK293 Cells', 'Hippocampus', 'Humans', 'Male', 'Orexin Receptors', 'Orexins', 'Phosphoryla... | 25,866,368 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['G02.206', 'G03.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Modification of sialic acid determination in erythrocytes]. | Various chromophores impair the evaluation of N-acetyl-neuraminic acid (NANA) of red blood cells by means of the thiobarbituric acid method according to WARREN. Therefore, a time consuming isolation of erythrocyte membranes is essential in order to avoid these shortcomings. The procedure was simplified by fixation with... | ['Erythrocyte Membrane', 'Erythrocytes', 'Histocytochemistry', 'Humans', 'Hydrolysis', 'Sialic Acids', 'Thiobarbiturates'] | 85,578 | [['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Aerobic exercise alone results in clinically significant weight loss for men and women: midwest exercise trial 2. | UNLABELLED: Exercise is recommended by public health agencies for weight management; however, the role of exercise is generally considered secondary to energy restriction. Few studies exist that have verified completion of exercise, measured the energy expenditure of exercise, and prescribed exercise with equivalent en... | ['Adolescent', 'Adult', 'Body Composition', 'Body Mass Index', 'Energy Intake', 'Energy Metabolism', 'Exercise', 'Female', 'Humans', 'Male', 'Obesity', 'Overweight', 'Sedentary Behavior', 'Weight Loss', 'Young Adult'] | 23,592,678 | [['M01.060.057'], ['M01.060.116'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G07.203.650.240.340'], ['G03.295'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.500', 'C23.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Histopathologic features of genetically determined ovarian cancer. | Inheritance of germline mutations of BRCA1 or BRCA2 genes account for approximately 10% of ovarian carcinomas, but the characterization of these genetically determined cancers is incomplete. The objective of our study was to characterize the histologic features of ovarian carcinomas associated with germline mutations o... | ['Female', 'Genes, BRCA1', 'Genes, BRCA2', 'Genetic Predisposition to Disease', 'Germ-Line Mutation', 'Humans', 'Ovarian Neoplasms', 'Prognosis', 'Risk Factors'] | 12,352,190 | [['G05.360.340.024.340.375.249.100', 'G05.360.340.024.340.415.400.100'], ['G05.360.340.024.340.375.249.105', 'G05.360.340.024.340.415.400.105'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.365.590.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.6... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Toxicity of oleic acid anilide in rats. | In the present investigation, we have studied the toxic potential of oleic acid anilide (OAA) and heated oleic acid anilide (HOAA) in relation to the toxic oil syndrome (TOS). Male Sprague-Dawley rats were given 250 mg/kg of OAA or HOAA in mineral oil by gavage, on alternate days for 2 weeks (total 7 doses). The contro... | ['Anilides', 'Animals', 'Body Weight', 'Hot Temperature', 'Immune System', 'Male', 'Oleic Acids', 'Organ Size', 'Rats', 'Rats, Inbred Strains'] | 1,759,851 | [['D02.065.199', 'D02.092.146.113'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['A15.382'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Socioeconomic inequalities in early childhood malnutrition and morbidity: modification of the household-level effects by the community SES. | This paper examines variations among communities in childhood malnutrition and diarrhea morbidity, explores the influences of socioeconomic status (SES) on child health, and investigates how the SES of families and that of communities interact in this process. Using multilevel modelling and data from Demographic and He... | ['Africa', 'Child', 'Child Mortality', 'Child, Preschool', 'Cluster Analysis', 'Data Collection', 'Diarrhea', 'Humans', 'Malnutrition', 'Social Class', 'Social Justice'] | 15,774,328 | [['Z01.058'], ['M01.060.406'], ['E05.318.308.985.550.287', 'N01.224.935.698.150', 'N06.850.505.400.975.550.287', 'N06.850.520.308.985.550.287'], ['M01.060.406.448'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['C23.888.821.214... | ['Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Increasing reports of non-tuberculous mycobacteria in England, Wales and Northern Ireland, 1995-2006. | BACKGROUND: Non-tuberculous mycobacteria have long been identified as capable of causing human disease and the number at risk, due to immune-suppression, is rising. Several reports have suggested incidence to be increasing, yet routine surveillance-based evidence is lacking. We investigated recent trends in, and the ep... | ['Adult', 'Female', 'Humans', 'Laboratories, Hospital', 'Male', 'Mandatory Reporting', 'Middle Aged', 'Mycobacterium', 'Mycobacterium Infections', 'Population Surveillance', 'United Kingdom'] | 20,950,421 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.420', 'N02.278.487.410', 'N04.452.442.452.422.420'], ['I01.880.604.583.080.134.300', 'I01.880.604.583.527', 'I01.880.604.622.249', 'N03.706.535.615', 'N03.706.657.249'], ['M01.060.116.630'], ['B03.510.024.962.500', 'B03.510.460.400... | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Acoustic radiation force impulse imaging of in vivo vastus medialis muscle under varying isometric load. | Acoustic Radiation Force Impulse (ARFI) imaging is a method for characterizing local variations in tissue mechanical properties. In this method, a single ultrasonic transducer array is used to both apply temporally short localized radiation forces within tissue and to track the resulting displacements through time. Ima... | ['Acoustics', 'Adult', 'Female', 'Humans', 'Isometric Contraction', 'Knee', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Transducers', 'Ultrasonography'] | 12,199,416 | [['H01.671.031'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A01.378.610.450'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['E07.305.812'], ['E01.370.350.850']] | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Lignan, sesquilignans and dilignans, novel HIV-1 protease and cytopathic effect inhibitors purified from the rhizomes of Saururus chinensis. | Five lignans were isolated from the ethyl acetate extracts of Saururus chinensis rhizomes and evaluated for anti-HIV-1 activity. Their structures were elucidated as two dilignans, manassantin A (1), manassantin B (2), two sesquilignans, saucerneol B (3) and saucerneol C (4), and a new lignan, saururin B (5) by spectros... | ['Cell Line', 'Cytopathogenic Effect, Viral', 'Dose-Response Relationship, Drug', 'HIV Protease Inhibitors', 'HIV-1', 'Humans', 'Inhibitory Concentration 50', 'Lignans', 'Molecular Structure', 'Rhizome', 'Saururaceae', 'Spectrum Analysis', 'T-Lymphocytes'] | 19,900,481 | [['A11.251.210'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389.745.900.500', 'D27.505.954.122.388.077.088.420'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690.9... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-inflammatory diterpene from Thyrsanthera suborbicularis. | Bioactivity-guided isolation on a n-hexane-soluble fraction of Thyrsanthera suborbicularis led to the isolation of a new rosane-type diterpene, 19-hydroxy-1(10), 15-rosadiene (1), along with three known compounds, taraxerol, acetyl aleuritolic acid, and spathulenol. The structures of isolated compounds were determined ... | ['Animals', 'Anti-Inflammatory Agents', 'Cell Line, Tumor', 'Diterpenes', 'Euphorbiaceae', 'Lipopolysaccharides', 'Macrophages', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Mice', 'Molecular Conformation', 'Nitric Oxide', 'Nitric Oxide Synthase Type II', 'RNA, Messenger'] | 21,372,422 | [['B01.050'], ['D27.505.954.158'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.455.849.291'], ['B01.650.940.800.575.912.250.859.797.438'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microbial colonization and sperm--mucus interaction: results in 1000 infertile couples. | After screening a large series of infertile patients (n = 1000 couples), potentially pathogenic microorganisms were identified in genital secretions of the majority of couples. None of the patients displayed signs or symptoms of infection of the lower genital tract. In semen specimens and cervical swabs, mycoplasmas we... | ['Adult', 'Bacteria, Anaerobic', 'Cervix Mucus', 'Colony Count, Microbial', 'Female', 'Humans', 'Infertility', 'Male', 'Middle Aged', 'Random Allocation', 'Retrospective Studies', 'Risk Factors', 'Semen', 'Sperm-Ovum Interactions'] | 1,639,978 | [['M01.060.116'], ['B03.130'], ['A12.200.503.339'], ['E01.370.225.875.220', 'E05.200.875.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365', 'C13.351.500.365'], ['M01.060.116.630'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E05.318.372.500.500.500', 'E05... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glucocorticoid with or without additional immunosuppressant therapy for patients with lupus podocytopathy: a retrospective single-center study. | Lupus podocytopathy is a newly recognized class of lupus nephritis characterized by extensive glomerular foot process effacement without capillary wall immune deposits. The treatment response and relapse of glucocorticoid with or without additional immunosuppressive agents has not been well investigated. In this study,... | ['Adolescent', 'Adult', 'Azathioprine', 'Cyclophosphamide', 'Drug Therapy, Combination', 'Female', 'Follow-Up Studies', 'Glucocorticoids', 'Humans', 'Immunosuppressive Agents', 'Isoxazoles', 'Kidney', 'Leflunomide', 'Lupus Nephritis', 'Male', 'Mycophenolic Acid', 'Nephrotic Syndrome', 'Podocytes', 'Prednisone', 'Protei... | 25,819,933 | [['M01.060.057'], ['M01.060.116'], ['D02.886.759.111', 'D03.633.100.759.570.090', 'D13.570.900.111'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E02.319.310'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preliminary studies on the detection, isolation and partial characterization of Clq-containing IgM immune complexes in sera of patients with primary biliary cirrhosis. | The complement system is activated in primary biliary cirrhosis (PBC) and this activated state may be medicated by immunoreactive IgM. To identify and further characterize the relationship between the complement (Clq) and IgM in PBC sera, we developed an anti-Clq ELISA method which allowed detection of Clq-containing c... | ['Antigen-Antibody Complex', 'Complement Activating Enzymes', 'Complement Activation', 'Complement C1', 'Complement C1q', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Immunoglobulin M', 'Liver Cirrhosis, Biliary'] | 3,259,541 | [['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D08.811.277.300', 'D12.776.124.486.274.045'], ['G12.274'], ['D12.776.124.486.274.050'], ['D12.776.124.486.274.050.270'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing the statistical power to detect linkage in a sample of 51 bipolar affective disorder pedigrees. | We used computer simulation method to address the question of power in an initial collaborative sample of 51 bipolar affective disorder pedigrees. Simulations were performed for all possible combinations using (1) two levels of diagnostic stringency, (2) three transmission models, (3) locus heterogeneity, and (4) diffe... | ['Adolescent', 'Adult', 'Aged', 'Bipolar Disorder', 'Chromosome Mapping', 'Computer Simulation', 'Female', 'Gene Frequency', 'Genes, Dominant', 'Genetic Carrier Screening', 'Genetic Linkage', 'Humans', 'Male', 'Middle Aged', 'Models, Genetic', 'Phenotype', 'Risk'] | 8,639,147 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F03.084.500'], ['E05.393.183'], ['L01.224.160'], ['G05.330'], ['G05.360.340.024.340.240', 'G05.420.320'], ['E01.370.225.562.250', 'E05.200.562.250', 'E05.393.435.250', 'N02.421.308.200', 'N02.421.726.233.221.250'], ['G05.348'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Clinical efficacy of Z-100 for the treatment of leukopenia caused by radiotherapy--a multi-center double-blind comparative study with L-cysteine]. | The clinical usefulness of Z-100 (Z group) for the treatment of leukopenia caused by radiotherapy for malignant tumors was evaluated by comparing it with that of L-cysteine (L group) by the double-blind method. For 178 complete cases, there were no significant differences in the time-course of the WBC during radiothera... | ['Adjuvants, Immunologic', 'Adult', 'Aged', 'Aged, 80 and over', 'Cysteine', 'Double-Blind Method', 'Female', 'Humans', 'Japan', 'Leukopenia', 'Lipids', 'Male', 'Mannans', 'Middle Aged', 'Neoplasms', 'Radiotherapy'] | 2,235,346 | [['D27.505.696.477.067'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hairy cell leukemia with translocation (11;20)(q13;q11) and overexpression of cyclin D1. | We report on a male Japanese patient with hairy cell leukemia (HCL). A cytogenetic study with lipopolysaccharide stimuli showed a novel translocation (11;20)(q13;q11) in 10% of the analyzed cells. Northern blot analysis and RT-PCR analysis for cyclin D1 revealed the overexpression of cyclin D1, although the southern bl... | ['Chromosomes, Human, Pair 11', 'Chromosomes, Human, Pair 20', 'Cyclin D1', 'Humans', 'Karyotyping', 'Leukemia, Hairy Cell', 'Male', 'Middle Aged', 'Translocation, Genetic'] | 10,456,674 | [['A11.284.187.520.300.325.355', 'G05.360.162.520.300.325.355'], ['A11.284.187.520.300.460.470', 'G05.360.162.520.300.460.470'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Why do not pregnant women want to get vaccinated against the flu? A scoping review]. | BACKGROUND: Pregnant women and newborns are at increased risk of complications from seasonal flu. Vaccination is effective and safe but there is low adherence in pregnant women. Objective: to identify the reasons that lead pregnant women not to be vaccinated against seasonal influenza.METHODS: Scoping Review in which w... | ['Female', 'Humans', 'Influenza Vaccines', 'Motivation', 'Patient Education as Topic', 'Pregnancy', 'Pregnant Women', 'Professional Role', 'Safety', 'Vaccination Refusal'] | 31,346,156 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['F01.658', 'F01.752.543.500.750'], ['I02.233.332.500', 'N02.421.726.407.680'], ['G08.686.784.769'], ['M01.975.807'], ['F01.829.316.616.625'], ['N06.850.135.060.075'], ['F01.100.150.750.750.500', 'F01.145.488.887.750.500', 'I01.880.604.473.650.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Mental health in L'Aquila after the earthquake. | INTRODUCTION: In the present work we describe the mental health condition of L'Aquila population in the aftermath of the earthquake in terms of structural, process and outcome perspectives.METHOD: Literature revision of the published reports on the L'Aquila earthquake has been performed.RESULTS: Although important psyc... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Age Factors', 'Antidepressive Agents', 'Antipsychotic Agents', 'Bereavement', 'Child', 'Child Development Disorders, Pervasive', 'Comorbidity', 'Depression', 'Drug Utilization', 'Earthquakes', 'Female', 'Humans', 'Italy', 'Male', 'Mass Casualty Incidents', 'Mental D... | 22,751,555 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.954.427.700.122'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F01.470.142'], ['M01.060.406'], ['F03.625.164'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.126.350'], ... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Experience with cyclophosphamide in multiple sclerosis: the cons. | Neurologists in the Kaiser-Permanente Medical Care Program recently designed a study to evaluate the utility of intensive immunosuppression with cyclophosphamide compared with folic acid in 44 patients with chronic progressive multiple sclerosis (MS). Although preliminary results based on incomplete data suggest cyclop... | ['Adult', 'Clinical Trials as Topic', 'Cyclophosphamide', 'Folic Acid', 'Follow-Up Studies', 'Humans', 'Immunosuppression', 'Immunotherapy', 'Middle Aged', 'Multiple Sclerosis'] | 3,290,708 | [['M01.060.116'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D03.633.100.733.631.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Constrictive chronic pericarditis in children. | Constrictive pericarditis is a uncommom disease in children. We have now encountered pericardial thickening as the cause of severe constrictive physiology in two patients, one also having haemodynamic features of restrictive cardiomyopathy. Both patients, who had refractory ascites and evidence of increased systemic ve... | ['Child', 'Chronic Disease', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Pericarditis, Constrictive'] | 11,293,741 | [['M01.060.406'], ['C23.550.291.500'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.720.595']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Imaging of radiation-associated sarcoma. | OBJECTIVE: The objective of this article is to show the imaging features of radiation-associated sarcoma arising after radiation therapy using multiple imaging modalities.CONCLUSION: A multimodality imaging strategy and collaboration between multidisciplinary teams are important for the management of radiation-associat... | ['Diagnostic Imaging', 'Humans', 'Neoplasms, Radiation-Induced', 'Radiotherapy', 'Sarcoma'] | 21,700,992 | [['E01.370.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.682', 'C26.733.476', 'G01.750.748.500.476'], ['E02.815'], ['C04.557.450.795']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical Features of Epithelial-Mesenchymal Transition in Feline Oral Squamous Cell Carcinoma. | Feline oral squamous cell carcinoma (FOSCC) is an aggressive malignancy with invasive and metastatic behavior. It is poorly responsive to chemotherapy and radiation. Neoplastic epithelial-mesenchymal transition (EMT) portends highly malignant behavior and enhances resistance to therapy. In transitioning to a more malig... | ['Animals', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'Cats', 'Cell Line, Tumor', 'Epithelial-Mesenchymal Transition', 'Immunohistochemistry', 'Mouth Neoplasms', 'Neoplastic Stem Cells', 'Phenotype'] | 31,331,247 | [['B01.050'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.356.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.23... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a lavage procedure to collect crop secretions from live chickens for studying crop immunity. | The crop (ingluvies), an organ for food storage in most avian species, is located at the base of the oesophagus. Previous work in our laboratory showed that, following infection with Salmonella enteritidis, significant anti-S. enteritidis antibody levels could be found in the crops of these birds. Samples in these prev... | ['Animals', 'Antibodies, Bacterial', 'Chickens', 'Crop, Avian', 'Salmonella enteritidis', 'Therapeutic Irrigation'] | 12,593,742 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A13.265'], ['B03.440.450.425.800.200.300', 'B03.660.250.150.710.160.160'], ['E02.779.492.500', 'E02.831.535.492.500', 'E05.927']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Geoacoustic inversion of ambient noise: a simple method. | The vertical directionality of ambient noise is strongly influenced by seabed reflections. Therefore, potentially, geoacoustic parameters can be inferred by inversion of the noise. In this approach, using vertical array measurements, the reflection loss is found directly by comparing the upward- with the downward-going... | ['Acoustics', 'Geology', 'Mediterranean Sea', 'Models, Theoretical', 'Noise'] | 12,398,445 | [['H01.671.031'], ['H01.277.562'], ['Z01.756.592'], ['E05.599'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610']] | ['Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Airway smooth muscle remodels pericellular collagen fibrils: implications for proliferation. | Airway wall remodeling comprises a broad range of structural changes including increases in the volume of airway smooth muscle (ASM) and fibrillar collagen. The impact of fibrillar collagen remodeling on ASM proliferation was investigated. Human ASM cultured on type I fibrillar collagen remodeled the collagen substrate... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Airway Remodeling', 'Cell Proliferation', 'Enzyme Activation', 'Extracellular Space', 'Female', 'Fibrillar Collagens', 'Gene Knockdown Techniques', 'Humans', 'Hydroxamic Acids', 'Indoles', 'Integrin beta1', 'Male', 'Matrix Metalloproteinase Inhibitors', 'Matrix Meta... | 20,081,066 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.017', 'G09.772.029'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.263', 'G03.328'], ['A10.082.500', 'A11.284.295'], ['D05.750.078.280.300', 'D12.776.860.300.250.300'], ['E05.393.335.500'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of novel indenoindoles. Part I. Structure-activity relationships in different model systems of lipid peroxidation. | Structure-activity relationships are presented for some representative compounds from a novel series of potent inhibitors of lipid peroxidation. The compounds are indenoindole derivatives with oxidation potentials in organic solvents of between 0.2 and 1.5 V. Two of these compounds, cis-5,5a,6,10b-tetrahydro-9-methoxy-... | ['Animals', 'Antioxidants', 'Dose-Response Relationship, Drug', 'Indoles', 'Lipid Peroxidation', 'Rats', 'Rats, Sprague-Dawley', 'Structure-Activity Relationship'] | 8,787,557 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.690.773.875', 'G07.690.936.500'], ['D03.633.100.473'], ['G02.111.515', 'G03.295.531.587'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.111.830', 'G07.690.773.997']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Eotaxin and monocyte chemoattractant protein-1 in chronic eosinophilic pneumonia. | Chronic eosinophilic pneumonia (CEP) is characterized by chronic or recurrent pulmonary infiltrates with eosinophils, but the precise mechanism of eosinophil accumulation has not been fully elucidated. Eotaxin is one of the CC chemokines that selectively recruits eosinophils and contributes to the pathogenesis of aller... | ['Adult', 'Aged', 'Bronchoalveolar Lavage Fluid', 'Chemokine CCL11', 'Chemokine CCL2', 'Chemokines, CC', 'Eosinophils', 'Female', 'Humans', 'Interleukin-5', 'Leukocyte Count', 'Lymphocyte Activation', 'Lymphocyte Count', 'Male', 'Middle Aged', 'Pulmonary Eosinophilia'] | 11,488,333 | [['M01.060.116'], ['M01.060.116.100'], ['E05.927.100.500'], ['D12.644.276.374.200.110.550', 'D12.776.467.374.200.110.550', 'D23.125.300.110.550', 'D23.469.200.110.550', 'D23.529.374.200.110.550'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Disrupted neural responses to phonological and orthographic processing in dyslexic children: an fMRI study. | Developmental dyslexia, characterized by difficulty in reading, has been associated with phonological and orthographic processing deficits. fMRI was performed on dyslexic and normal-reading children (8-12 years old) during phonological and orthographic tasks of rhyming and matching visually presented letter pairs. Duri... | ['Child', 'Dominance, Cerebral', 'Dyslexia', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Parietal Lobe', 'Phonetics', 'Reading', 'Temporal Lobe'] | 11,209,939 | [['M01.060.406'], ['F02.830.297', 'G11.561.225'], ['C10.597.606.150.500.300', 'C10.597.606.150.550.200', 'C23.888.592.604.150.500.300', 'C23.888.592.604.150.550.200', 'F03.625.562.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.186.211.200.885.287.500.670'], ['L01.559.598.518'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Report of an audit into third molar exodontia. | A postal audit of the main surgical variables in third molar exodontia under general anaesthesia was undertaken on consultants holding a National Health contract within the British Isles. This first paper presents the results. A response rate of 175 returned questionnaires from the 247 consultants was obtained (70.9%).... | ['Adolescent', 'Adult', 'Alveolectomy', 'Analgesics', 'Anesthesia, Dental', 'Anesthesia, Local', 'Anti-Bacterial Agents', 'Dental Service, Hospital', 'Drug Utilization', 'Education, Dental', 'Education, Medical', 'Humans', 'Medical Audit', 'Molar, Third', 'Mouthwashes', 'State Medicine', 'Sutures', 'Tooth Extraction', ... | 1,622,965 | [['M01.060.057'], ['M01.060.116'], ['E04.545.550.110', 'E06.645.550.110'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['E03.155.141', 'E06.045'], ['E03.155.086.231'], ['D27.505.954.122.085'], ['N02.278.216.500.968.298', 'N02.421.240.200', 'N04.452.442.452.422.298'], ['N04.452.706.477'], ['I02.358.274'], ['I02.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Modeling Disease Progression via Multisource Multitask Learners: A Case Study With Alzheimer's Disease. | Understanding the progression of chronic diseases can empower the sufferers in taking proactive care. To predict the disease status in the future time points, various machine learning approaches have been proposed. However, a few of them jointly consider the dual heterogeneities of chronic disease progression. In parti... | ['Algorithms', 'Alzheimer Disease', 'Datasets as Topic', 'Disease Progression', 'Humans', 'Linear Models', 'Machine Learning', 'Neural Networks, Computer', 'Neuroimaging', 'Time Factors'] | 26,929,064 | [['G17.035', 'L01.224.050'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.308.056', 'L01.313.500.750.300.188.400.500', 'L01.399.250.224', 'L01.470.750.750.431', 'N05.715.360.300.224', 'N06.850.520.308.056'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Assay of the Ca pump ATPase activity of intact red blood cells. | An assay for the Ca pump ATPase of intact human red blood cells (RBCs) was developed. The assay utilized a small volume (typically 10 microliters) of packed RBCs in 1 ml of a buffer of known composition. The assay was based on the exposure of intact RBCs to the ionophore, A23187, in the presence of Ca. Such exposure ca... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Calcimycin', 'Calcium-Transporting ATPases', 'Cations, Divalent', 'Erythrocyte Membrane', 'Erythrocytes', 'Humans', 'In Vitro Techniques', 'Kinetics', 'Magnesium'] | 1,316,164 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D03.633.100.221.173'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['D01.248.497.300.333'], ['A11.118.290.27... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Herpes zoster infection increases the risk of peripheral arterial disease: A nationwide cohort study. | Varicella-zoster virus infection can cause meningoencephalitis, myelitis, ocular disorders, and vasculopathy. However, no study has investigated the association between herpes zoster (HZ) and peripheral arterial disease (PAD).We identified newly diagnosed HZ from the Taiwan's National Health Insurance Research Database... | ['Aged', 'Case-Control Studies', 'Comorbidity', 'Female', 'Herpes Zoster', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Peripheral Arterial Disease', 'Retrospective Studies', 'Risk Factors', 'Taiwan'] | 27,583,856 | [['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N05.715.350.225', 'N06.850.490.687'], ['C01.925.256.466.930.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.98... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Aerosol chemistry and the effect of aerosol water content on visibility impairment and radiative forcing in Guangzhou during the 2006 Pearl River Delta campaign. | Optical and chemical aerosol measurements were obtained from 2 to 31 July 2006 at an urban site in the metropolitan area of Guangzhou (China) as part of the Program of Regional Integrated Experiment of Air Quality over Pearl River Delta (PRIDE-PRD2006) to investigate aerosol chemistry and the effect of aerosol water co... | ['Aerosols', 'Air Pollutants', 'Algorithms', 'Ammonium Sulfate', 'China', 'Environmental Monitoring', 'Nitrates', 'Particle Size', 'Particulate Matter', 'Water Pollutants, Chemical'] | 19,523,748 | [['D20.280.055', 'D26.255.165.055'], ['D27.888.284.101'], ['G17.035', 'L01.224.050'], ['D01.625.062.374', 'D01.875.800.800.850.050'], ['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['G02.712'], ['D20.633'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Effects on dental health of spacing of teeth in anterior segments. | The purpose of the study was to examine the relationship between spacing and dental health in 15-year-old adolescents. The whole sample consisted of 156 subjects. Out of them, 74 females and 73 males with 6 anterior teeth made up the study group for examination of the upper jaw. 75 females and 75 males had 6 anterior t... | ['Adolescent', 'Cuspid', 'Dental Plaque Index', 'Dental Restoration, Permanent', 'Dentition', 'Diastema', 'Female', 'Humans', 'Incisor', 'Male', 'Odontometry', 'Oral Health', 'Periodontal Index', 'Sex Factors'] | 6,589,240 | [['M01.060.057'], ['A14.549.167.860.200'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['A03.556.500.379', 'A14.549.167'], ['C07.650.800.320', 'C07.793.700.320', 'C16.131.8... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Torsional resistance of crowns cemented to composite cores involving three stainless steel endodontic post designs. | STATEMENT OF PROBLEM: There are no studies analyzing the effects of a crown in relationship to torsional resistance for a titanium-reinforced core material supported by a post.PURPOSE: This study investigated the effects of post design on the torsional resistance of a crown supported by a titanium-reinforced composite ... | ['Analysis of Variance', 'Composite Resins', 'Crowns', 'Dental Prosthesis Design', 'Dental Stress Analysis', 'Dentin-Bonding Agents', 'Humans', 'Incisor', 'Post and Core Technique', 'Resin Cements', 'Stainless Steel', 'Statistics, Nonparametric', 'Torque'] | 10,898,840 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.780.346.250', 'E07.695.190.088'], ['E06.780.346.625', 'E06.912.145'], ['E06.308'], ['D25.339.291.300', 'J01.637.051.339.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Lactic acid bacteria growth promoters from Spirulina platensis. | Spirulina has been used for many years as human food because of its high protein content and nutritional value. Some strains also produce bioactive substances that may inhibit or promote microbial growth. Lactococcus lactis, Streptococcus thermophilus, Lactobacillus casei, Lactobacillus acidophilus, and Lactobacillus b... | ['Culture Media', 'Cyanobacteria', 'Food Microbiology', 'Growth Substances', 'Lactobacillus', 'Streptococcus'] | 9,927,000 | [['D27.720.470.305', 'E07.206'], ['B03.280', 'B03.440.475.100'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['D27.505.696.377'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['B03.353.750.737.872'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Expression of transferrin receptors and intracellular ferritin during terminal differentiation of human monocytes. | Human blood monocytes when cultured on hydrophobic Teflon membranes differentiate into mature macrophages. The expression of transferrin receptors was monitored by monoclonal antibody (OKT9) binding as detected by immunoperoxidase staining. Whereas monocytes were negative, an increasing percentage of macrophages, start... | ['Antibodies, Monoclonal', 'Cell Differentiation', 'Ferritins', 'Humans', 'Immunoenzyme Techniques', 'Lung', 'Macrophages', 'Monocytes', 'Peritoneum', 'Phenotype', 'Pleura', 'Receptors, Cell Surface', 'Receptors, Transferrin'] | 6,089,939 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.152'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A04.411'], ['A11.329.372', 'A11.627.482', 'A11.733.39... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of liver transplant quality in France]. | The French Biomedecine Agency evaluated the outcomes of liver transplantation in France. The one-year graft failure rate in each transplant center was compared with the national rate, after adjusting for recipient, donor and transplant characteristics. All patients transplanted from 1998 to 2002 were included, except w... | ['France', 'Graft Rejection', 'Graft Survival', 'Humans', 'Liver Transplantation', 'Quality Assurance, Health Care'] | 18,666,461 | [['Z01.542.286'], ['G12.875.545.328'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['N04.761.700', 'N05.700']] | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Patterns of primary glomerular diseases among adults in the western region of Saudi Arabia. | The frequency of primary glomerular diseases is variable from one part of the world to the other. Data published from Saudi Arabia has shown wide range of variation in the different regions of the country. This study reports the frequency of primary glomerulonephritis (GN) in adults in the Western region of Saudi Arabi... | ['Adolescent', 'Adult', 'Aged', 'Biopsy', 'Diagnosis, Differential', 'Glomerulonephritis', 'Humans', 'Kidney Glomerulus', 'Microscopy, Electron', 'Middle Aged', 'Morbidity', 'Prognosis', 'Saudi Arabia', 'Young Adult'] | 19,237,826 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Nursing home glaucoma and visual acuity screening results in western Oklahoma. | Six hundred and four patients from 19 nursing homes in rural western Oklahoma underwent visual acuity and glaucoma screening. Thirty-seven percent (221/604) had corrected near visual acuity less than or equal to 20/200 in one or both eyes. Fourty-nine percent (298/604) had best distance visual acuity less than or equal... | ['Adolescent', 'Adult', 'Aged', 'Glaucoma', 'Humans', 'Middle Aged', 'Nursing Homes', 'Oklahoma', 'Visual Acuity'] | 3,994,220 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N02.278.825.610'], ['Z01.107.567.875.510.550'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
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