Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Analysis of ion channel expression by astrocytes in red nucleus brain stem slices of the rat. | The red nucleus (RN) has been widely used to study the formation and remodeling of synaptic connections during development and in post-lesion plasticity. Since glial cells are thought to contribute to synaptic plasticity, and information on functional properties of brain stem glia is missing, we analyzed voltage-gated ... | ['Animals', 'Astrocytes', 'Brain Stem', 'Electric Conductivity', 'Female', 'Ion Channel Gating', 'Ion Channels', 'Neuroglia', 'Potassium', 'Rats', 'Rats, Wistar', 'Receptors, Glutamate', 'Red Nucleus', 'Sodium', 'alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid'] | 9,063,730 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211.132'], ['G01.358.500.249.277'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['A08.637', 'A11.650'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B0... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of animal experimentation: United States of America. | Two national mechanisms regulate the humane treatment of the 20-40 million laboratory animals that are used annually for experimental purposes in the United States each year. They are: the Public Health Service policy (commonly called the National Institutes of Health (NIH) policy) of 1985, and the Animal Welfare Act o... | ['Animal Testing Alternatives', 'Animal Welfare', 'Animals', 'Legislation, Veterinary', 'National Institutes of Health (U.S.)', 'United States'] | 3,469,871 | [['E05.017.080.100'], ['I01.880.604.100'], ['B01.050'], ['N03.706.615.686'], ['I01.409.418.750.600.650.496', 'N03.540.052.750', 'N03.540.348.500.500.600.650.496'], ['Z01.107.567.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Microbial Disruption Indices to Detect Colonization With Multidrug-Resistant Organisms. | OBJECTIVE To characterize the microbial disruption indices of hospitalized patients to predict colonization with multidrug-resistant organisms (MDROs). DESIGN A cross-sectional survey of the fecal microbiome was conducted in a tertiary referral, acute-care hospital in Boston, Massachusetts. PARTICIPANTS The study popul... | ['Aged', 'Cross Infection', 'Cross-Sectional Studies', 'Drug Resistance, Multiple, Bacterial', 'Feces', 'Female', 'Humans', 'Male', 'Microbiota', 'Middle Aged', 'RNA, Ribosomal, 16S', 'Tertiary Care Centers'] | 28,899,445 | [['M01.060.116.100'], ['C01.248', 'C23.550.291.875.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.591', 'G16.500.27... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The bovine alpha-lactalbumin promoter directs expression of ovine trophoblast interferon in the mammary gland of transgenic mice. | A hybrid construct derived from ovine trophoblastin cDNA and bovine alpha-lactalbumin-encoding gene, was injected into the pronuclei of mouse eggs. In one of the resulting transgenic mouse lines, expression of the hybrid construct was detected and found to be limited to the mammary gland of lactating females which secr... | ['Animals', 'Base Sequence', 'Blotting, Southern', 'Cattle', 'Cloning, Molecular', 'DNA', 'Female', 'Gene Expression Regulation', 'Interferon Type I', 'Lactalbumin', 'Mammary Glands, Animal', 'Mice', 'Mice, Transgenic', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Restriction Mapping', 'Sheep', 'Transcripti... | 2,060,621 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['B01.050.150.900.649.313.500.380.271'], ['E05.393.220'], ['D13.444.308'], ['G05.308'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['D12.776.034.398', 'D12.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ecdysteroids as regulators of host and parasite interactions: a study of interrelationships between Schistosoma mansoni and the host snail, Biomphalaria glabrata. | Ecdysteroids have been detected in trematode parasites and in several species of gastropod snails. The potential role of these and other hormones as regulators of host/parasite interactions is discussed. This study considers the role of ecdysteroids in the host parasite interactions between Schistosoma mansoni and Biom... | ['Animals', 'Biomphalaria', 'Chemotaxis', 'Ecdysteroids', 'Ecdysterone', 'Female', 'Herb-Drug Interactions', 'Host-Parasite Interactions', 'Invertebrate Hormones', 'Oviposition', 'Plant Extracts', 'Schistosoma mansoni'] | 2,052,849 | [['B01.050'], ['B01.050.500.644.400.750.185'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['D04.210.500.247.222.265.165', 'D04.210.500.247.808.756.143', 'D06.472.445.573.271', 'D10.570.938.795.143', 'D23.704.500.143'], ['D04.210.500.247.222.265.1... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Carbon nanotube signal amplification for ultrasensitive fluorescence polarization detection of DNA methyltransferase activity and inhibition. | A versatile sensing platform based on multiwalled carbon nanotube (MWCNT) signal amplification and fluorescence polarization (FP) is developed for the simple and ultrasensitive monitoring of DNA methyltransferase (MTase) activity and inhibition in homogeneous solution. This method uses a dye-labeled DNA probe that poss... | ['Biosensing Techniques', 'DNA Methylation', 'Drug Evaluation, Preclinical', 'Enzyme Assays', 'Enzyme Inhibitors', 'Fluorescence Polarization', 'Humans', 'Nanotubes, Carbon', 'Site-Specific DNA-Methyltransferase (Adenine-Specific)'] | 24,287,418 | [['E05.601.043'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['E05.290.750', 'E05.337.550'], ['E05.196.427'], ['D27.505.519.389'], ['E05.196.712.516.600.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['D08.811.913.555.500.350.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Geochemistry and quality of groundwater of the Yarmouk basin aquifer, north Jordan. | Quality of groundwater in the Yarmouk basin, Jordan has been assessed through the study of hydrogeochemical characteristics and the water chemistry as it is considered the main source for drinking and agriculture activities in the region. The results of the relationship between Ca2+ + Mg2+ versus HCO3- + CO32-, Ca2+ + ... | ['Agricultural Irrigation', 'Anions', 'Cations', 'Environmental Monitoring', 'Groundwater', 'Hydrogen-Ion Concentration', 'Jordan', 'Water Pollutants, Chemical'] | 29,299,860 | [['J01.040.044'], ['D01.248.497.158'], ['D01.248.497.300'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.355'], ['G02.300'], ['Z01.252.245.500.400'], ['D27.888.284.903.655']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Cystic neoplasms of the exocrine pancreas. | Cystic neoplasms of the pancreas are rare and their diagnosis and treatment can be difficult. This report details 7 patients who had histologically proven serous cystadenoma, mucinous cystadenoma and cystadeno carcinoma. Computed tomography and sonography allowed excellent preoperative assessment but to attempt a disti... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cystadenocarcinoma', 'Cystadenoma', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Tomography, X-Ray Computed'] | 2,278,913 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.480', 'C04.557.470.590.480'], ['C04.557.470.035.320', 'C04.557.470.590.485'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Perceptions of a tattooed college instructor. | 128 undergraduates' perceptions of tattoos on a model described as a college instructor were assessed. They viewed one of four photographs of a tattooed or nontattooed female model. Students rated her on nine teaching-related characteristics. Analyses indicated that the presence of tattoos was associated with some posi... | ['Adult', 'Attitude', 'Character', 'Faculty', 'Female', 'Humans', 'Professional Competence', 'Social Desirability', 'Students', 'Tattooing', 'Teaching'] | 20,712,173 | [['M01.060.116'], ['F01.100'], ['F01.752.190'], ['M01.526.702.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.399.630'], ['F01.145.813.628'], ['M01.848'], ['E02.218.085.840', 'E04.085.840'], ['I02.903']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
An Early Report of the Use of a Modular Dual Mobility Articulation in Revision Acetabular Reconstruction. | BACKGROUND: Instability remains one of the main problems after revision hip surgery. The aim of this study was to review the clinical, radiological, and patient-reported outcomes with the use of modular dual-mobility articulation for revision acetabular reconstruction and investigate the risk of fretting corrosion by m... | ['Acetabulum', 'Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Chromium', 'Cobalt', 'Corrosion', 'Female', 'Follow-Up Studies', 'Hip Prosthesis', 'Humans', 'Ions', 'Longitudinal Studies', 'Male', 'Metals', 'Middle Aged', 'Osteoarthritis', 'Prosthesis Design', 'Range of Motion, Articular', 'Reop... | 29,807,791 | [['A02.835.232.043.825.108'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['G02.165'], ['E05.318.372.500.750.249', '... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Photodynamic activity of chlorin e6 and chlorin e6 ethylenediamide in vitro and in vivo. | Several parameters of chlorin e6 and its derivative chlorin e6 ethylenediamide have been investigated as these compound are potential sensitizers for photodynamic therapy. A study carried out to compare the cellular uptake of the pigments indicates that chlorin e6 ethylenediamide possesses an enhanced affinity for tumo... | ['Animals', 'Biological Transport', 'Carcinoma, Ehrlich Tumor', 'Ethylenediamines', 'Kinetics', 'Light', 'Methylcholanthrene', 'Mice', 'Mice, Inbred Strains', 'Photochemotherapy', 'Porphyrins', 'Radiation-Sensitizing Agents', 'Sarcoma, Experimental', 'Tissue Distribution', 'Tumor Cells, Cultured'] | 1,403,368 | [['B01.050'], ['G03.143'], ['C04.557.470.200.200', 'C04.619.169'], ['D02.092.782.258.368'], ['G01.374.661', 'G02.111.490'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02.455.426.559.847.149.500', 'D04.615.149.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum dehydroepiandrosterone sulphate, total antioxidant capacity, and total oxidant status in central serous chorioretinopathy. | BACKGROUND: The objective of this work is to evaluate plasma total antioxidant capacity (TAC), total oxidant status (TOS), and dehydroepiandrosterone sulphate (DHEA-S) levels in patients diagnosed with acute central serous chorioretinopathy (CSCR) and control samples.METHODS: The TAC, TOS, and DHEA-S levels were assess... | ['Acute Disease', 'Adult', 'Antioxidants', 'Central Serous Chorioretinopathy', 'Dehydroepiandrosterone Sulfate', 'Female', 'Humans', 'Luminescent Measurements', 'Male', 'Oxidants'] | 23,749,383 | [['C23.550.291.125'], ['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C11.768.175'], ['D04.210.500.054.079.429.625.300', 'D04.210.500.578.502.400.300', 'D06.472.040.502.400.300', 'D06.472.334.851.968.952.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.516'], ['D27... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Successful treatment of Legionella pneumonia with moxifloxacin in a hemodialysis patient]. | Moxifloxacin, a recent, new quinolone agent, has superior pharmacokinetics and appears to be safe for patients with renal failure, as it is mainly excreted in the bile. The case of a hemodialysis patient with Legionella pneumonia who was successfully treated with moxifloxacin is reported. A 76-year-old woman, who had b... | ['Aged', 'Anti-Infective Agents', 'Aza Compounds', 'Female', 'Fluoroquinolones', 'Humans', "Legionnaires' Disease", 'Moxifloxacin', 'Pneumonia, Bacterial', 'Quinolines', 'Renal Dialysis'] | 19,637,806 | [['M01.060.116.100'], ['D27.505.954.122'], ['D02.145'], ['D03.633.100.810.835.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.500.501', 'C01.748.382.380', 'C08.730.382.380'], ['D03.633.100.810.835.322.327'], ['C01.150.252.620', 'C01.748.610.540', 'C08.381.677.540', 'C08.730.610.540'], ['D03.63... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rabies post-exposure vaccination in 2 visits within a week: A 4-site intradermal regimen. | Rabies is fatal in all unvaccinated patients bitten by dogs, and so post-exposure vaccine regimens must be robust enough to ensure their survival under all conditions. Treatment tends to be excessive for most people, but there is justified anxiety about reducing vaccine dosage and shortening regimens. Recently, World H... | ['Bites and Stings', 'Drug Administration Schedule', 'Humans', 'Immunization Schedule', 'Injections, Intradermal', 'Post-Exposure Prophylaxis', 'Practice Guidelines as Topic', 'Rabies', 'Rabies Vaccines', 'Rabies virus', 'Vaccination', 'World Health Organization'] | 30,691,982 | [['C25.723.127', 'C26.176'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.470', 'E05.478.550.545'], ['E02.319.267.530.620.410'], ['N02.421.726.755'], ['N04.761.700.350.650', 'N05.700.350.650'], ['C01.925.782.580.830.750'], ['D20.215.894.899.700'], ['B04.820.480.937.750.500.700... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Syntagmatic and paradigmatic development of cochlear implanted children in comparison with normally hearing peers up to age 7. | OBJECTIVE: Grammatical development is shown to be delayed in CI children. However, the literature has focussed mainly on one aspect of grammatical development, either morphology or syntax, and on standard tests instead of spontaneous speech. The aim of the present study was to compare grammatical development in the spo... | ['Case-Control Studies', 'Child', 'Child, Preschool', 'Cochlear Implants', 'Cross-Sectional Studies', 'Female', 'Humans', 'Language', 'Language Development', 'Male', 'Speech', 'Speech Production Measurement'] | 26,199,138 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene. | Apolipoprotein B (apoB) mRNA editing consists of a posttranscriptional C-->U conversion involving the first base of the codon CAA encoding glutamine-2153 to UAA, a stop codon, in apoB mRNA. Using a cloned rat cDNA as a probe, we cloned the cDNA and genomic sequences of the gene for a human apoB mRNA editing protein. Ex... | ['APOBEC-1 Deaminase', 'Base Sequence', 'Chromosome Mapping', 'Cloning, Molecular', 'Cytidine Deaminase', 'DNA Primers', 'Gene Expression', 'Genes', 'Humans', 'Intestine, Small', 'Macromolecular Substances', 'Molecular Sequence Data', 'Protein Binding', 'Protein Biosynthesis', 'RNA, Messenger', 'Sequence Alignment', 'S... | 8,078,915 | [['D08.811.277.151.486.250.500.500'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['E05.393.220'], ['D08.811.277.151.486.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.297'], ['G05.360.340.024.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The degradation of platelet-activating factor and related lipids: susceptibility to phospholipases C and D. | 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) is an ether-linked lipid that exhibits selective cytotoxicity toward several types of tumor cells and is relatively inactive toward normal cells under the same conditions of treatment. The mechanis of this selective cytotoxicity is unknown. We conducted... | ['Animals', 'Antineoplastic Agents', 'Humans', 'Phospholipase D', 'Phospholipases', 'Phospholipid Ethers', 'Platelet Activating Factor', 'Rats', 'Rats, Inbred Strains', 'Tumor Cells, Cultured', 'Type C Phospholipases'] | 3,444,369 | [['B01.050'], ['D27.505.954.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.352.640.700.710'], ['D08.811.277.352.100.680', 'D08.811.277.352.640.700'], ['D02.033.800.875.875.750', 'D02.355.460.750', 'D10.570.755.375.760.400.985'], ['D02.033.100.291.211.500', 'D02.092.063.291.211.500', 'D02.092.877.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. | Emerging evidence suggests that RANKL-induced changes in chromatin state are important for osteoclastogenesis, but these epigenetic mechanisms are not well understood and have not been therapeutically targeted. In this study, we find that the small molecule I-BET151 that targets bromo and extra-terminal (BET) proteins ... | ['Animals', 'Bone Resorption', 'Cell Differentiation', 'Cells, Cultured', 'Epigenesis, Genetic', 'Female', 'Heterocyclic Compounds, 4 or More Rings', 'Humans', 'Inflammation', 'Mice', 'Mice, Inbred C57BL', 'NFATC Transcription Factors', 'Osteoclasts', 'Osteogenesis', 'Osteoporosis', 'Ovariectomy', 'RANK Ligand'] | 25,391,636 | [['B01.050'], ['C05.116.264', 'G11.427.213.150'], ['G04.152'], ['A11.251'], ['G05.308.203'], ['D03.633.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.776.930.6... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Circulation, oxygen and acid-base balance in the extremities in response to stimulation of the sympathetic trunk]. | The lumbar part of the dog right sympathetic trunk was stimulated with the 20 Hz current. This entailed a rise of general and regional arterial tension, a reduction of arterial lumen in the extremity, a decrease of volume blood flow and pulse blood content, a retardation of microcirculation, a decline of oxygen tension... | ['Acid-Base Equilibrium', 'Animals', 'Dogs', 'Electric Stimulation', 'Electrochemistry', 'Hindlimb', 'Male', 'Microcirculation', 'Muscles', 'Oxidation-Reduction', 'Oxygen', 'Regional Blood Flow', 'Sympathetic Nervous System'] | 3,699,188 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.723.402'], ['H01.181.529.307'], ['A13.473'], ['G09.330.100.645'], ['A02.633', 'A10.690'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670'], ['G09.330.100.780'], ['A08.8... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Plastid transcriptomics and translatomics of tomato fruit development and chloroplast-to-chromoplast differentiation: chromoplast gene expression largely serves the production of a single protein. | Plastid genes are expressed at high levels in photosynthetically active chloroplasts but are generally believed to be drastically downregulated in nongreen plastids. The genome-wide changes in the expression patterns of plastid genes during the development of nongreen plastid types as well as the contributions of trans... | ['Chloroplasts', 'Introns', 'Lycopersicon esculentum', 'Oligonucleotide Array Sequence Analysis', 'Plant Proteins', 'Plastids', 'Promoter Regions, Genetic', 'Protein Biosynthesis', 'RNA Editing', 'RNA Splicing', 'RNA, Messenger', 'Transcription, Genetic'] | 18,441,214 | [['A11.284.430.214.190.875.700.140'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['B01.650.940.800.575.912.250.908.500.322'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['D12.776.765'], ['A11.284.430.214.190.875.700'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical under staging of high risk nonmuscle invasive urothelial carcinoma treated with radical cystectomy. | PURPOSE: The role of radical cystectomy in patients with nonmuscle invasive urothelial carcinoma of the bladder remains controversial. The risk of overtreatment must be balanced against the potential benefit of aggressive therapy. We reviewed our results in these patients with a particular emphasis on clinical under st... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Transitional Cell', 'Cystectomy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Retrospective Studies', 'Urinary Bladder Neoplasms'] | 11,458,053 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.430'], ['E04.950.774.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.8... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Trends in premature avertable mortality from non-communicable diseases for 195 countries and territories, 1990-2017: a population-based study. | BACKGROUND: The reduction by a third of premature non-communicable disease (NCD) mortality by 2030 is the ambitious target of Sustainable Development Goal (SDG) 3.4. However, the indicator is narrowly defined, including only four major NCDs (cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases) a... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Global Health', 'Humans', 'Male', 'Middle Aged', 'Mortality, Premature', 'Noncommunicable Diseases', 'Sustainable Development', 'Young Adult'] | 32,199,120 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['H02.403.371', 'N01.400.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.550.550', 'N01.224.935.698.700', 'N06.850.505.400.975.550.550', 'N06.850.520.308.... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Tube angulation effect on radiographic analysis of the implant-abutment interface. | The purpose of this study was to determine the maximum permissible x-ray tube angulation that can be used to verify the fit of an abutment. An implant and an abutment were assembled with an abutment screw. A variety of openings were created between the abutment and the implant. Radiographs were taken combining the diff... | ['Chi-Square Distribution', 'Dental Abutments', 'Dental Implants', 'Dental Impression Materials', 'Dental Prosthesis Design', 'Humans', 'Observer Variation', 'Polyvinyls', 'Radiography, Dental', 'Siloxanes', 'Surface Properties'] | 10,074,756 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E06.780.346.500', 'E07.695.190.175'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['D25.339.334', 'J01.637.051.339.334'], ['E06.780.346.625', 'E06.912.145'], ['B01.050.150.900.649.313.988.400.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Determination of activity for nociceptin in the mouse vas deferens. | The recently discovered neuropeptide nociceptin was found to inhibit electrically induced contractions of the mouse vas deferens. Nociceptin and its 14-Tyr analog were each partial agonists, but with high affinity (ED50 of 20 nM). This activity was not opioid in nature, as it was not inhibited by either selective or no... | ['Animals', 'Dose-Response Relationship, Drug', 'Electrophysiology', 'Male', 'Mice', 'Muscle Contraction', 'Narcotic Antagonists', 'Opioid Peptides', 'Rats', 'Receptors, Opioid', 'Vas Deferens'] | 8,791,013 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.992.635.505.500'], ['G11.427.494'], ['D27.505.696.543', 'D27.505.696.663.850.512', 'D27.505.954.427.550'], ['D12.644.400.575', 'D12.776.631.650.575'], ['B01.050.150.900.649.313.992.635.505.700'], ['D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Assessment of internal thoracic artery grafts using duplex scanning]. | In an effort to develop a noninvasive method to evaluate flow characteristics of the internal thoracic artery grafts (ITAG) after coronary artery bypass grafting, we performed duplex scanning of ITAGs of 51 patients who underwent bypass grafting. The ITAG was visualized with a duplex scanner of 7.5 MHz through the firs... | ['Adult', 'Aged', 'Coronary Artery Bypass', 'Coronary Circulation', 'Female', 'Humans', 'Male', 'Mammary Arteries', 'Middle Aged', 'Ultrasonography, Doppler, Duplex', 'Vascular Patency'] | 10,402,783 | [['M01.060.116'], ['M01.060.116.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['G09.330.100.324'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.891.525'], ['M01.060.116.630'], ['E01.370.350.850.850.850'], ['G09.330.920']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The structures of katanosins A and B. | 1H and 13C NMR studies on katanosin A confirmed the presence of eight usual amino acid residues which were previously deduced by amino acid analysis and suggested the presence of beta-hydroxyaspartic acid, beta-hydroxyleucine and beta-phenylserine residues. These amino acids were isolated and confirmed, including their... | ['Amino Acid Sequence', 'Amino Acids', 'Anti-Bacterial Agents', 'Chemical Phenomena', 'Chemistry', 'Depsipeptides', 'Peptides'] | 3,403,365 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['D27.505.954.122.085'], ['G02'], ['H01.181'], ['D04.345.566.297', 'D12.644.641.297'], ['D12.644']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Behavioral rehabilitation of functional alexia. | A 10-year-old boy with a functional reading deficit (i.e. functional alexia) was successfully treated with hospital based escape/avoidance procedures. A multiple baseline design was used to evaluate the effectiveness of treatment. Generalization of treatment effects across individuals, settings and time was demonstrate... | ['Behavior Therapy', 'Child', 'Dyslexia, Acquired', 'Humans', 'Male', 'Pattern Recognition, Visual', 'Somatoform Disorders'] | 3,611,386 | [['F04.754.137'], ['M01.060.406'], ['C10.597.606.150.500.300.200', 'C10.597.606.150.550.200.500', 'C23.888.592.604.150.500.300.200', 'C23.888.592.604.150.550.200.500', 'F03.615.700', 'F03.625.562.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F03.875']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Clinical effectiveness of carbenicillin in suppurative inflammatory processes of varying localization]. | The study on sensitivity of clinical strains of the causative agents of purulent infections to carbenicillin showed that 34.6% of the staphylococcal strains, 48.1% of the E. coli strains and 40.3% of the Proteus strains were sensitive to the antibiotic. The strains of Ps. aeruginosa were characterized by moderate sensi... | ['Adult', 'Ampicillin', 'Carbenicillin', 'Clinical Trials as Topic', 'Drug Evaluation', 'Drug Therapy, Combination', 'Gentamicins', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases', 'Inflammation', 'Microbial Sensitivity Tests', 'Suppuration'] | 380,455 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
N-linked oligosaccharide chains of the insulin receptor beta subunit are essential for transmembrane signaling. | Insulin receptor (IR) is a glycoprotein possessing N-linked oligosaccharide side chains on both alpha and beta subunits. The present study focuses for the first time on the potential contribution of N-linked oligosaccharides of the beta subunit in the processing, structure, and function of the insulin receptor. To inve... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Base Sequence', 'CHO Cells', 'Cell Membrane', 'Cricetinae', 'Cysteine', 'Fluorescent Antibody Technique', 'Glycosylation', 'Humans', 'Insulin', 'Iodine Radioisotopes', 'Kinetics', 'Macromolecular Substances', 'Methionine', 'Molecular Sequence Data', 'Mutagen... | 1,324,936 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.200', 'A11.436.155'], ['A11.284.149'], ['B01.050.150.900.649.313.992.635.075.250'], ['D02.886.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Diagnostic accuracy of CSF neurofilament light chain protein in the biomarker-guided classification system for Alzheimer's disease. | We assessed the diagnostic accuracy of cerebrospinal fluid (CSF) neurofilament light chain (NFL) protein in the classification of patients with Alzheimer's disease (AD) and cognitively healthy control individuals (HCs) and patients with frontotemporal dementia (FTD) as comparisons. Particularly, we tested the performan... | ['Aged', 'Alzheimer Disease', 'Amyloid beta-Peptides', 'Biomarkers', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neurofilament Proteins', 'Peptide Fragments', 'Pilot Projects', 'Retrospective Studies', 'tau Proteins'] | 28,527,630 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D23.101'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D05.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of de novo microdeletions involving 17q11.2q12 identified through chromosomal comparative genomic hybridization. | High-resolution array-comparative genome hybridization (CGH) is a powerful tool for detection of submicroscopic chromosome deletions and duplications. We describe two patients with mild mental retardation (MR) and de novo microdeletions of 17q11.2q12. Although the deletions did not involve the neurofibromatosis type 1 ... | ['Child', 'Child, Preschool', 'Chromosome Deletion', 'Chromosomes, Human, Pair 17', 'Cytogenetic Analysis', 'Developmental Disabilities', 'Female', 'Humans', 'Male', 'Nucleic Acid Hybridization'] | 17,916,097 | [['M01.060.406'], ['M01.060.406.448'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187.520.300.415.425', 'G05.360.162.520.300.415.425'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.39... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension. | BACKGROUND: We previously reported that administration of elastase inhibitors reverses fatal pulmonary arterial hypertension (PAH) in rats by inducing smooth muscle cell (SMC) apoptosis. We showed in pulmonary artery (PA) organ culture that the mechanism by which elastase inhibitors induce SMC apoptosis involves repres... | ['Animals', 'Apoptosis', 'Enzyme Inhibitors', 'ErbB Receptors', 'Hypertension, Pulmonary', 'Integrin alphaVbeta3', 'Male', 'Metalloproteases', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'Organ Culture Techniques', 'Protease Inhibitors', 'Quinazolines', 'Rats', 'Rats, Sprague-Dawley', 'Tyrphostins'] | 16,027,270 | [['B01.050'], ['G04.146.954.035'], ['D27.505.519.389'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['C08.381.423', 'C14.907.489.556'], ['D12.776.395.550.625.439', 'D12.776.543.550.625.439', 'D12.776.543.750.705.408.460.870.500', 'D12.776.543.750.705.675.541'], ['D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular bases of cytoskeleton plasticity during the Trypanosoma brucei parasite cycle. | African trypanosomes are flagellated protozoan parasites responsible for sleeping sickness and transmitted by tsetse flies. The accomplishment of their parasite cycle requires adaptation to highly diverse environments. These transitions take place in a strictly defined order and are accompanied by spectacular morpholog... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'Cytoskeleton', 'Flagella', 'Fluorescent Antibody Technique', 'Gastrointestinal Tract', 'Proventriculus', 'Salivary Glands', 'Trypanosoma brucei brucei', 'Tsetse Flies'] | 21,159,115 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.284.430.214.190.750'], ['A11.284.180.290'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A03.556'], ['A13.853.710'], ['A03.556.500.760', 'A10.336.779', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ribavirin monotherapy in patients with chronic hepatitis C: a retrospective study of 95 patients. | Ribavirin is a purine nucleoside that inhibits the replication of a variety of RNA viruses and was shown to have a transient efficacy in chronic hepatitis C during short-term therapy. We have analysed retrospectively its efficacy in 95 patients with liver biopsy-proven chronic hepatitis C. Patients received oral ribavi... | ['Adult', 'Aged', 'Antiviral Agents', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Liver', 'Male', 'Middle Aged', 'Retrospective Studies', 'Ribavirin', 'Treatment Outcome'] | 9,658,373 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.388'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) gene polymorphisms and type 2 diabetes mellitus: a meta-analysis. | BACKGROUND: The association between peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) polymorphisms and type 2 diabetes mellitus (T2DM) has been investigated in several studies, but these studies yielded contradictory results. We conducted a meta-analysis to assess the association between ... | ['Diabetes Mellitus, Type 2', 'Genetic Predisposition to Disease', 'Heat-Shock Proteins', 'Humans', 'Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha', 'Polymorphism, Genetic', 'Risk Factors', 'Transcription Factors'] | 21,294,239 | [['C18.452.394.750.149', 'C19.246.300'], ['C23.550.291.687.500', 'G05.380.355'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.024.314.650', 'D12.776.157.057.080.650', 'D12.776.157.725.813.875', 'D12.776.476.024.394.650', 'D12.776.660.675.650', 'D12.776.664.962.813.875', 'D12.776.9... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of fiber orientation on the polymerization shrinkage strain of fiber-reinforced composites. | OBJECTIVE: The aim of this study was to characterize the linear polymerization shrinkage strain of glass fiber-reinforced composite (FRC) according to the fiber orientation.METHODS: Test specimens (n=5) (10.0 x 10.0 x 1.5mm) were prepared from different brands of photopolymerizable resin-preimpregnated FRC; unidirectio... | ['Anisotropy', 'Composite Resins', 'Dental Stress Analysis', 'Glass', 'Hardness', 'Phase Transition'] | 16,239,026 | [['G01.590.040', 'G02.050'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.308'], ['J01.637.437'], ['G01.374.647'], ['G01.645', 'G02.734']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Colonic conduit for esophageal replacement: long-term endoscopic and histopathologic changes in colonic mucosa. | BACKGROUND: Long-term follow-up has substantiated the colon as a durable and highly acceptable esophageal substitute. Exposure of colonic conduit to gastric acid may lead to histopathologic changes in the form of chronic inflammation.MATERIALS/METHODS: Thirty children with esophageal replacement were studied from 2 to ... | ['Adolescent', 'Anastomosis, Surgical', 'Biopsy', 'Child', 'Child, Preschool', 'Colon', 'Esophageal Atresia', 'Esophagoscopy', 'Esophagus', 'Female', 'Follow-Up Studies', 'Gastroesophageal Reflux', 'Humans', 'Infant', 'Infant, Newborn', 'Intestinal Mucosa', 'Male', 'Postoperative Complications', 'Stomach', 'Treatment O... | 22,974,602 | [['M01.060.057'], ['E04.035'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['M01.060.406'], ['M01.060.406.448'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C06.198.330', 'C06.405.117.260', 'C16.131.314.330'], ['E01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical and pharmacogenetics associated with recovery time from general anesthesia. | AIM: Delayed recovery from general anesthesia is a well-known complication that requires predictive tools and approaches. This study aimed to determine significant factors associated with postanesthesia recovery and to develop an algorithm for estimating recovery time from general anesthesia.MATERIALS & METHODS: The ge... | ['ATP Binding Cassette Transporter, Subfamily G, Member 2', 'Algorithms', 'Anesthesia Recovery Period', 'Anesthesia, General', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pain', 'Pharmacogenetics', 'Prospective Studies', 'Receptors, Opioid, mu', 'Time Factors'] | 30,136,624 | [['D12.776.157.530.100.228.500', 'D12.776.395.550.020.457.500', 'D12.776.543.550.192.457.500', 'D12.776.543.585.100.228.500'], ['G17.035', 'L01.224.050'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['E03.155.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.592.612',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Biofilm activity and sludge characteristics affected by exogenous N-acyl homoserine lactones in biofilm reactors. | This study verified the effect of N-acyl homoserine lactone (AHL) concentrations on mature biofilm systems. Three concentrations of an AHL mixture were used in the batch test. Introducing of 5nM AHLs significantly increased biofilm activity and increased sludge characteristics, which resulted in better pollutant remova... | ['Acyl-Butyrolactones', 'Bacteria', 'Biofilms', 'Bioreactors', 'Chromatography, High Pressure Liquid', 'Nitrification', 'Nitrogen', 'Quorum Sensing', 'Sewage', 'Tandem Mass Spectrometry', 'Waste Management'] | 27,030,953 | [['D02.540.232'], ['B03'], ['A20.593', 'G06.120'], ['E07.115', 'J01.897.120.115'], ['E05.196.181.400.300'], ['G02.111.587.500', 'G02.607.560.500', 'G16.500.768.500'], ['D01.268.604', 'D01.362.625'], ['G04.085.700', 'G06.550.700'], ['D20.944.932.500'], ['E05.196.566.880'], ['N06.850.780.200.800.800.900', 'N06.850.860.51... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Infectivity of cultured Trypanosoma fallisi (Kinetoplastida) to various anuran species and its evolutionary implications. | Trypanosoma fallisi, a hemoflagellate infecting Bufo americanus from Ontario, was grown in vitro, and metatrypanosomes from the primary culture were inoculated into 4 uninfected test groups from 3 anuran families: Bufonidae, Hylidae, and Ranidae. In vitro-cultured T. fallisi was found to infect B. americanus and to ind... | ['Animals', 'Anura', 'Biological Evolution', 'Bufonidae', 'Ranidae', 'Trypanosoma'] | 2,040,964 | [['B01.050'], ['B01.050.150.900.090.180'], ['G05.045', 'G16.075'], ['B01.050.150.900.090.180.210'], ['B01.050.150.900.090.180.708'], ['B01.268.475.868.887']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation and function of GADD45gamma in unilateral ureteral obstruction. | We performed differential display analysis to determine transcriptional activity in the rat kidney, following unilateral ureteral obstruction and found a 12-fold increase in the expression of Growth Arrest and DNA Damage-45gamma (GADD45gamma), a stress-responsive molecule that interacts with cell-cycle proteins. GADD45... | ['Adenoviridae', 'Animals', 'Apoptosis', 'Cell Proliferation', 'Cells, Cultured', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Kidney Diseases', 'Kidney Tubules', 'Male', 'Mitogen-Activated Protein Kinase Kinases', 'Oligonucleotide Array Sequence Analysis', 'RNA, Messenger', 'RNA, Small Interfering', 'Ra... | 18,354,378 | [['B04.280.030'], ['B01.050'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['C12.777.419', 'C13.351.968.419'], ['A05.810.453.736.560'], ['D08.811.913.696.620.682.700.565', 'D08.811.913.696.620.682.725.200', 'D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Advances in radiological anatomy of the kidney. | While using cortical nephrotomography to show the architecture and thickness of the cortical septa we have observed, in 76 out of 176 kidneys, the presence of 2 distinct parenchymal elements for which we suggest the term "renunculus". In such cases the upper renunculus is posterior relative to the lower. It lies rather... | ['Female', 'Humans', 'Kidney', 'Kidney Cortex', 'Male', 'Tomography, X-Ray', 'Tomography, X-Ray Computed', 'Tuberculosis, Renal'] | 7,104,566 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['A05.810.453.324'], ['E01.370.350.700.810', 'E01.370.350.825.810'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['C01.150.252.410.040.552.846.944.847', 'C12.67... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age and individual variability in performance during sleep restriction. | The effect of sleep loss on reaction time (RT) performance varies as a function of age, with RTs of older subjects typically showing less decrement (relative to rested baseline) than those of younger subjects. In the current paper, we examined the nature of this relationship in a 7-day sleep restriction study. The numb... | ['Adult', 'Aging', 'Attention', 'Female', 'Humans', 'Individuality', 'Male', 'Middle Aged', 'Models, Statistical', 'Pattern Recognition, Visual', 'Psychometrics', 'Psychomotor Performance', 'Reaction Time', 'Sleep Deprivation'] | 17,118,094 | [['M01.060.116'], ['G07.345.124'], ['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F04.711.780'], ['F02.808', 'G11.427.700', 'G1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oral manifestations of lupus erythematosus - report of two cases. | BACKGROUND: Lupus erythematosus is a serious autoimmune disease, which can cause oral mucosal lesions, manifesting as white striae and erythematous, atrophic and hyperkeratotic areas, as well as erosions and ulcerations. Sometimes, these signs can be misdiagnosed as other oral diseases such as lichen planus. Also, on h... | ['Adult', 'Aged, 80 and over', 'Diagnosis, Differential', 'Female', 'Fluorescent Antibody Technique, Direct', 'Follow-Up Studies', 'Humans', 'Lip Diseases', 'Lupus Erythematosus, Discoid', 'Lupus Erythematosus, Systemic', 'Mouth Diseases', 'Mouth Mucosa', 'Palate'] | 23,489,373 | [['M01.060.116'], ['M01.060.116.100.080'], ['E01.171'], ['E01.370.225.500.607.512.240.300', 'E01.370.225.750.551.512.240.300', 'E05.200.500.607.512.240.300', 'E05.200.750.551.512.240.300', 'E05.478.583.375.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.90... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Results of pharmacoepidemiological study of arterial hypertension in Russia (PIFAGOR)]. | AIM: To assess physicians preferences concerning the use of various groups of antihypertensive drugs in Russia.METHODS: Special questionnaires containing 8 questions related to preferential adherence to representatives of various groups of antihypertensive drugs were distributed among practicing physicians who routinel... | ['Antihypertensive Agents', 'Drug Utilization', 'Epidemiologic Studies', 'Humans', 'Hypertension', "Practice Patterns, Physicians'", 'Russia'] | 14,671,558 | [['D27.505.954.411.162'], ['N04.452.706.477'], ['E05.318.372.500', 'N05.715.360.330.500', 'N06.850.520.450.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['N04.590.374.577', 'N05.300.625'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Structural abnormalities of the inferoseptal left ventricular wall detected by cardiac magnetic resonance imaging in carriers of hypertrophic cardiomyopathy mutations. | OBJECTIVES: The purpose of this study was to evaluate whether structural left ventricular (LV) abnormalities can be observed in hypertrophic cardiomyopathy (HCM) mutation carriers who have not yet developed echocardiographic signs of hypertrophy by using cardiac magnetic resonance imaging (CMR).BACKGROUND: Hypertrophic... | ['Adult', 'Cardiomyopathy, Hypertrophic', 'Female', 'Heart Ventricles', 'Heterozygote', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Mutation'] | 17,174,192 | [['M01.060.116'], ['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['A07.541.560'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['G05.365.590']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Combined endoscopic endonasal surgery and fractionated stereotactic radiosurgery (fSRS) for complex cranial base tumors-early clinical outcomes. | Endoscopic endonasal surgery (EES) has been shown to be a feasible approach to cranial base tumors while reducing post-operative morbidity. Using the endoscopic endonasal approach alone or in combination with open approaches may provide advantages over conventional approaches. However, the balance between maximal resec... | ['Adult', 'Aged', 'Aged, 80 and over', 'Endoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Morbidity', 'Postoperative Complications', 'Radiosurgery', 'Skull Base Neoplasms', 'Treatment Outcome'] | 20,815,420 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525', 'N01.224.935.597', 'N06.850.505.400.975.525', 'N06.850.520.308.985.525'], ['C23.550.767'], ['E02.815.530', 'E04.525.800.650', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of cochlear tonotopy on electrically evoked compound action potentials (ECAPs). | BACKGROUND: A wide range of cochlear implant electrode designs exists. Lateral wall electrodes may be favored for their potential to preserve residual hearing by virtue of being thin and delicate; whereas perimodiolar electrodes may have advantages in case of profound hearing loss, due to electrode positioning in close... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Cochlear Implants', 'Cochlear Nerve', 'Evoked Potentials', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Young Adult'] | 30,652,918 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['A08.800.800.120.910.120'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Basics of Compounding: Standardization of Compounded Medications. | The feasibility of standardizing concentrations of compounded drug preparations to attempt to minimize adverse events of both nonsterile and sterile compounded preparations has been discussed. It is critical that a wide variety of opinions and potential "unintended consequences" be aired in the public before an issue l... | ['Drug Compounding', 'Pharmacists', 'Reference Standards'] | 30,668,534 | [['E05.916.270'], ['M01.526.485.780', 'N02.360.780'], ['E05.978.808']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Angiotensin II-dependent proximal tubule sodium transport is mediated by cAMP modulation of phospholipase C. | Angiotensin II (ANG II) stimulates proximal tubule sodium transport by decreasing adenylyl cyclase activity. The role of ANG II-dependent phospholipase C is less certain. To determine the contribution of phospholipase C and adenylyl cyclase to apical (AP) ANG II-dependent sodium transport, unidirectional (AP to basolat... | ['Adenylyl Cyclases', 'Angiotensin II', 'Animals', 'Biological Transport', 'Calcium Channel Blockers', 'Cell Membrane', 'Cells, Cultured', 'Cyclic AMP', 'Estrenes', 'Gallic Acid', 'Kidney Tubules, Proximal', 'Male', 'Pyrrolidinones', 'Rats', 'Rats, Sprague-Dawley', 'Sodium', 'Type C Phospholipases'] | 7,977,687 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['G03.143'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['A11.284.149']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative cost analysis of hemilaryngectomy and irradiation for early glottic carcinoma. | The cost of hemilaryngectomy (15 patients) was compared to that of radiation treatment (18 patients) in epidermoid carcinoma confined to the true vocal cord with normal mobility (T1N0). An average of $3,495 was saved if radiation therapy was chosen; savings in terms of working hours were also substantial. We maintain t... | ['Carcinoma, Squamous Cell', 'Costs and Cost Analysis', 'Humans', 'Laryngeal Neoplasms', 'Laryngectomy', 'Missouri', 'Radiotherapy'] | 6,841,194 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['N03.219.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['E04.580.369'], ['Z01.107.567.875.510.515'], ['E02.815']] | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Protein synthesis by granulation tissue in bipedicle tube flaps. | The protein synthesis and the collagen synthesis by 2- to 7-week-old granulation tissue from implanted cylinders in bipedicle tube flaps on rabbits were measured in vitro by the incorporation of 14C-proline in proteins and in collagen hydroxyproline. Granulation tissue from cylinders implanted in skin folds were used a... | ['Animals', 'Collagen', 'Female', 'Foreign Bodies', 'Granulation Tissue', 'Male', 'Methods', 'Proline', 'Rabbits', 'Skin', 'Time Factors', 'Wound Healing'] | 1,162,291 | [['B01.050'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C26.392'], ['A10.165.450'], ['E05.581'], ['D12.125.072.401.623'], ['B01.050.150.900.649.313.968.700'], ['A17.815'], ['G01.910.857'], ['G16.762.891']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative SEM studies of the enamel surface appearance following the use of glass ionomer cement and a diacrylate resin for bracket bonding. | The enamel surface appearance after the use of glass ionomer cement and a diacrylate resin for orthodontic bracket bonding was compared in an in vivo test using scanning electron microscopy and an enamel surface index system. Significant alterations in the enamel surface were found irrespective of the bonding procedure... | ['Acid Etching, Dental', 'Acrylic Resins', 'Composite Resins', 'Dental Bonding', 'Dental Debonding', 'Dental Enamel', 'Glass Ionomer Cements', 'Humans', 'Microscopy, Electron, Scanning', 'Orthodontic Brackets', 'Replica Techniques', 'Resin Cements', 'Silicon Dioxide', 'Tooth Abrasion'] | 8,236,031 | [['E06.931.475.111'], ['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.095'], ['E06.178'], ['A14.549.167.900.255'], ['D25.339.291.402', 'J01.637.051.339.291.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Latent Class Analysis of Gambling Activities in a Sample of Young Swiss Men: Association with Gambling Problems, Substance Use Outcomes, Personality Traits and Coping Strategies. | The study aimed to identify different patterns of gambling activities (PGAs) and to investigate how PGAs differed in gambling problems, substance use outcomes, personality traits and coping strategies. A representative sample of 4989 young Swiss males completed a questionnaire assessing seven distinct gambling activiti... | ['Adaptation, Psychological', 'Adult', 'Behavior, Addictive', 'Comorbidity', 'Female', 'Gambling', 'Humans', 'Male', 'Personality', 'Risk Factors', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Sweden', 'Young Adult'] | 25,929,440 | [['F01.058'], ['M01.060.116'], ['F01.145.527.100.120'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.722.408', 'F03.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Sudden monocular visual loss in pseudotumor cerebri. | We describe a patient with papilledema due to benign intracranial hypertension who had sudden, painless monocular visual loss. Fear of further visual deterioration prompted vigorous therapeutic efforts to reduce intracranial pressure. Subsequent neuro-ophthalmologic evaluation disclosed that the visual loss was due to ... | ['Blindness', 'Fluorescein Angiography', 'Functional Laterality', 'Fundus Oculi', 'Humans', 'Intracranial Pressure', 'Male', 'Middle Aged', 'Papilledema', 'Pseudotumor Cerebri', 'Remission, Spontaneous', 'Retinal Diseases', 'Retinal Hemorrhage'] | 454,249 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Karyofund of Chironomus plumosus (Diptera, Chronomidae) in the Palearctic region]. | Quantitative and qualitative analyses of chromosomal polymorphism in 38 Palearctic populations of Chironomus plumosus were made. It was shown that most of the populations studied were highly polymorphic: in average 63.2 +/- 4.0% of larvae were heterozygous for inversions with 0.95 + 0.08 heterozygous inversion per larv... | ['Animals', 'Chironomidae', 'Chromosome Banding', 'Chromosomes', 'Karyotyping', 'Polymorphism, Genetic'] | 11,517,668 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.750'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['A11.284.187', 'A11.284.430.106.279.345.190', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An investigation of the pathology and pathogens associated with porcine respiratory disease complex in Denmark. | Respiratory infections are among the most important diseases of growing pigs. In order to elucidate the multifactorial aetiology of porcine respiratory disease complex (PRDC) in Denmark, lungs from 148 finishing pigs with cranioventral bronchopneumonia (case group) and 60 pigs without lung lesions (control group) were ... | ['Abattoirs', 'Animals', 'Bronchopneumonia', 'Circovirus', 'Denmark', 'Lung', 'Mycoplasma hyopneumoniae', 'Mycoplasma hyorhinis', 'Pasteurella multocida', 'Porcine Reproductive and Respiratory Syndrome', 'Porcine respiratory and reproductive syndrome virus', 'Swine', 'Swine Diseases'] | 20,181,357 | [['J01.576.423.200.700.100', 'J03.540.020'], ['B01.050'], ['C01.748.610.127', 'C08.127.509', 'C08.381.677.127', 'C08.730.610.127'], ['B04.280.120.150'], ['Z01.542.816.124'], ['A04.411'], ['B03.440.860.580.553.553.420'], ['B03.440.860.580.553.553.425'], ['B03.440.450.600.600.500', 'B03.660.250.550.590.500'], ['C01.925.7... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
A case of adult-onset Satoyoshi syndrome with gastric ulceration and eosinophilic enteritis. | BACKGROUND: The patient was misdiagnosed as having Sj?gren's syndrome (on the basis of a lower-limb rash and dry eyes and mouth) in 1999, and then as having systemic lupus erythematosus (on the basis of hair loss and a high antinuclear antibody titer) in 2005. Total alopecia, muscular spasms and diarrhea developed over... | ['Enteritis', 'Eosinophilia', 'Female', 'Humans', 'Middle Aged', 'Spasm', 'Stomach Ulcer', 'Syndrome'] | 18,607,399 | [['C06.405.205.462', 'C06.405.469.326'], ['C15.378.553.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.613.750', 'C23.888.592.608.750'], ['C06.405.469.275.800.849', 'C06.405.748.586.849'], ['C23.550.288.500']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rumen microbial diversity in Svalbard reindeer, with particular emphasis on methanogenic archaea. | Ruminal methanogens, bacteria and ciliate protozoa of Svalbard reindeer grazing natural pastures in October (late fall) and April (late winter) were investigated using molecular-based approaches. The appetite of the Svalbard reindeer peaks in August (summer) and is at its lowest in March (winter). Microbial numbers, qu... | ['Alveolata', 'Animals', 'Archaea', 'Bacteria', 'DNA, Archaeal', 'DNA, Bacterial', 'DNA, Protozoan', 'Female', 'Gene Library', 'RNA, Ribosomal, 16S', 'Reindeer', 'Rumen', 'Sequence Analysis, DNA'] | 19,702,875 | [['B01.043'], ['B01.050'], ['B02'], ['B03'], ['D13.444.308.180'], ['D13.444.308.212'], ['D13.444.308.442'], ['G05.360.325'], ['D13.444.735.686.670'], ['B01.050.150.900.649.313.500.380.373.644'], ['A13.869.804'], ['E05.393.760.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A P300-based Brain Computer Interface Using Stereo-electroencephalography Signals. | Stereo-electroencephalography (SEEG) signals can be obtained by implanting deep intracranial electrodes, which are currently used for epileptic diagnosis. In this study, we implemented a P300-based Brain Computer Interface (BCI) using SEEG signals. 40 buttons corresponding to 40 numbers displayed in a graphical user in... | ['Brain', 'Brain-Computer Interfaces', 'Electrodes, Implanted', 'Electroencephalography', 'Epilepsy', 'Event-Related Potentials, P300', 'Humans', 'User-Computer Interface'] | 31,946,534 | [['A08.186.211'], ['E07.305.076'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['G07.265.216.500.350', 'G11.561.200.500.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900.910']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Eicosenoic and docosenoic acid incorporation in serum lipoproteins in rats fed rapeseed oil. | Rats were fed rapeseed oil rich in eicosenoic (20:1) and docosenoic (22:1) acids for 7 days, and the fatty acid composition of the lipid classes of serum and serum lipoproteins was determined. Concentrations of 20:1 and 22:1 acids in the lipid classes were variable, especially among lipoproteins, and were a direct func... | ['Animals', 'Brassica', 'Cholesterol', 'Dietary Fats', 'Fasting', 'Fatty Acids, Unsaturated', 'Lipoproteins', 'Male', 'Oils', 'Phospholipids', 'Rats', 'Triglycerides'] | 634,044 | [['B01.050'], ['B01.650.940.800.575.912.250.157.200'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D10.251.355'], ['D10.532', 'D12.776.521'], ['D10.627'], ['D10.570.755'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Clinical importance of antineutrophil cytoplasmic antibody positivity during propylthiouracil treatment. | BACKGROUND: Propylthiouracil (PTU) is the mainstay of antithyroid drug therapy. Previous studies reported antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis in patients treated for Graves' disease. ANCA has been associated with either PTU or to the disease itself. However, this issue has not been investigat... | ['Adult', 'Aged', 'Antibodies, Antineutrophil Cytoplasmic', 'Antithyroid Agents', 'Female', 'Graves Disease', 'Humans', 'Male', 'Middle Aged', 'Propylthiouracil', 'Thyroid Function Tests', 'Young Adult'] | 18,284,438 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323.190', 'D12.776.124.790.651.114.323.190', 'D12.776.377.715.548.114.323.190', 'D23.101.050'], ['D06.347.100', 'D27.505.696.399.450.100'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Semisynthetic Glycoconjugate Vaccines To Elicit T Cell-Mediated Immune Responses and Protection against Streptococcus pneumoniae | Streptococcus pneumoniae serotype 3 (ST3) is one of the main pneumococcal strains that can cause severe invasive diseases, but its current vaccines are relatively inefficient. To develop more effective ST3 vaccines, tetanus toxoid (TT) conjugates of the synthetic penta-, hexa-, hepta-, and octasaccharide analogs of ST3... | ['Animals', 'Antibodies, Bacterial', 'CD4-Positive T-Lymphocytes', 'Female', 'Glycoconjugates', 'Lung', 'Mice', 'Mice, Inbred BALB C', 'Pneumococcal Infections', 'Polysaccharides, Bacterial', 'Serogroup', 'Streptococcal Vaccines', 'Streptococcus pneumoniae', 'Tetanus Toxoid', 'Th1 Cells'] | 31,126,171 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D09.400'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrasound: an aid to diagnosing gallstones in the radiographically nonvisualized gallbladder. | The accuracy and reproducibility of ultrasound as a modality to identify gallstones were evaluated. A credible result raises the possibility of the use of ultrasound to diagnose gallstones in the radiographically nonvisualized gallbladder. | ['Cholelithiasis', 'Humans', 'Radiography', 'Ultrasonography'] | 400,875 | [['C06.130.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['E01.370.350.850']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of the in vivo genotoxicity of 2-hydroxy 4-methoxybenzophenone. | The genotoxic potential of 2-hydroxy 4-methoxy-benzophenone (benzophenone-3, Bz-3), a commonly used sunscreen, has been evaluated previously with in vitro systems. Data from Salmonella studies (with and without activation) have been predominantly negative, but two reports have shown weakly positive results in a single ... | ['Animals', 'Benzophenones', 'Bone Marrow', 'Bone Marrow Cells', 'Chromosome Aberrations', 'Drosophila melanogaster', 'Female', 'Male', 'Mutagenesis', 'Mutagenicity Tests', 'Mutagens', 'Rats', 'Rats, Sprague-Dawley', 'Sunscreening Agents', 'Wings, Animal'] | 8,013,479 | [['B01.050'], ['D02.455.426.559.389.134', 'D02.522.223'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.558'], ['E05.393.560', 'E05.940.560'], ['D27.888.569.468'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Age and individual characteristics in the structure of the celiac trunk in man]. | The individual and developmental features of the structure of the celiac trunk were studied in 155 human corpses of either sex, age and habitus. The method used was the dissection preceded by the injection of vessels with roentgen-contrast masses and roentgenography. The individual and developmental features of the lev... | ['Adolescent', 'Adult', 'Age Factors', 'Body Constitution', 'Celiac Artery', 'Child', 'Child, Preschool', 'Female', 'Genetic Variation', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged'] | 901,191 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115', 'G07.100'], ['A07.015.114.207'], ['M01.060.406'], ['M01.060.406.448'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.116.630']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Elevated Lin28B expression is correlated with lymph node metastasis in oral squamous cell carcinomas. | BACKGROUND: Lymph node (LN) metastasis is the most common cause of oral squamous cell carcinoma (OSCC)-related death. Searching the detailed molecular mechanisms involved LN metastasis in OSCC is still an open question.METHODS: Paired tissue samples from tumor (T) and adjacent non-cancerous matched tissues (NCMT) parts... | ['Adult', 'Aged', 'Arecoline', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Neoplasm Invasiveness', 'RNA-Binding Proteins', 'Real-Time Polymera... | 25,726,847 | [['M01.060.116'], ['M01.060.116.100'], ['D03.066.515.292', 'D03.132.080', 'D03.383.725.547.292'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.443'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The comparative test performance of dot filter hybridization (Viratype) and conventional morphologic analysis to detect human papillomavirus. | To investigate the test performance of a commercially available detection kit for human papillomavirus (HPV), the relationship between the detection of HPV by dot filter hybridization (DFH) and by standard morphologic methods was studied. Four hundred two cervical samples taken from 381 patients referred to a colposcop... | ['Adolescent', 'Adult', 'Aged', 'Biopsy', 'Female', 'Humans', 'Middle Aged', 'Nucleic Acid Hybridization', 'Papillomaviridae', 'Tumor Virus Infections', 'Uterine Cervical Diseases', 'Vaginal Smears'] | 1,309,483 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.393.661', 'G02.111.611'], ['B04.280.210.655',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dissection of Saccharomyces cerevisiae asci. | Yeast is a highly tractable model system that is used to study many different cellular processes. The common laboratory strain Saccharomyces cerevisiae exists in either a haploid or diploid state. The ability to combine alleles from two haploids and the ability to introduce modifications to the genome requires the prod... | ['Diploidy', 'Mycology', 'Saccharomyces cerevisiae', 'Spores, Fungal'] | 19,455,096 | [['G05.700.264'], ['H01.158.273.540.553'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['A11.870.710', 'A19.374.500', 'B05.775.710']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Incorporating oliguria into the diagnostic criteria for acute kidney injury after on-pump cardiac surgery: impact on incidence and outcomes. | OBJECTIVES: Consensus definitions represent an important step toward defining the epidemiology of acute kidney injury (AKI). However, the oliguric component of these definitions remains of uncertain impact and utility after cardiac surgery. The authors sought to define the specific impact of oliguric criteria, both alo... | ['Acute Kidney Injury', 'Adult', 'Aged', 'Aged, 80 and over', 'Cardiac Surgical Procedures', 'Cohort Studies', 'Coronary Artery Bypass', 'Creatinine', 'Critical Care', 'Female', 'Hospital Mortality', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Oliguria', 'ROC Curve', 'Renal Replacement Therapy', 'Retrospective Studi... | 23,735,469 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.100.376', 'E04.928.220'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['D03.383.129.308.207'... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glutathione-S-transferase pi expression in transitional cell carcinoma of the bladder. | Glutathione-S-transferase pi (GST pi) is a multifunctional protein that acts as an enzyme, involved in the detoxification of drugs and carcinogens. It has been implicated both in drug resistance and malignant transformation of epithelium. Using an indirect immunohistochemical technique, we have evaluated cytoplasmic an... | ['Carcinoma, Transitional Cell', 'Cell Nucleus', 'Cytoplasm', 'Drug Resistance', 'Glutathione Transferase', 'Humans', 'Urinary Bladder', 'Urinary Bladder Neoplasms'] | 8,281,406 | [['C04.557.470.200.430'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214'], ['G07.690.773.984'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.890'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351.937.820.945', 'C13.351.968.829.707']] | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A randomized, controlled dose response study of intravenous sodium diethyldithiocarbamate in patients with advanced human immunodeficiency virus infection. | Sodium diethyldithiocarbamate (Imuthiol, DTC) has previously been observed to promote T-cell maturation in animal models and to reduce lymphadenopathy and improve survival in a murine AIDS model. In addition, several clinical studies have suggested that one dosage regimen may be active in patients with HIV infection. W... | ['AIDS-Related Complex', 'Acquired Immunodeficiency Syndrome', 'Adult', 'Ditiocarb', 'Dose-Response Relationship, Drug', 'Drug Tolerance', 'Female', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Randomized Controlled Trials as Topic'] | 2,557,513 | [['C01.221.250.875.080', 'C01.221.812.640.400.080', 'C01.778.640.400.080', 'C01.925.782.815.616.400.080', 'C01.925.813.400.080', 'C01.925.839.080', 'C20.673.480.080'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Developmental regulation of calcium-binding proteins (calelectrins and calpactin I) in mammary glands. | We recently showed that mammary glands contain a novel class of calcium-binding proteins (CBPs) that bind to membranes in a calcium-dependent manner. We have also established that these mammary CBPs are equivalent to the calelectrins and calpactin I/p36. Since it has been suggested that these proteins might be involved... | ['Animals', 'Annexins', 'Blotting, Western', 'Calcium-Binding Proteins', 'Cells, Cultured', 'Collagen', 'Epithelium', 'Fluorescent Antibody Technique', 'In Vitro Techniques', 'Mammary Glands, Animal', 'Mice', 'Molecular Weight'] | 2,522,458 | [['B01.050'], ['D12.776.157.125.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.157.125'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A10.272'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pasteurella haemolytica cytotoxin: production by recognized serotypes and neutralization by type-specific rabbit antisera. | A sterile culture supernatant from each of the 12 recognized serotypes of Pasteurella haemolytica was toxic to bovine alveolar macrophages when assayed by 51Cr release. Types appeared to differ in their ability to liberate cytotoxin, although this may have reflected strain variation rather than serotype-related differe... | ['Animals', 'Antibodies, Bacterial', 'Bacterial Vaccines', 'Cytotoxins', 'Immune Sera', 'Pasteurella', 'Rabbits', 'Serotyping', 'Vaccination'] | 6,869,971 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D20.215.894.135'], ['D27.888.569.213'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['B03.440.450.600.600', 'B03.660.250... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inflammatory pseudotumor of the liver. Ultrasound and CT features. | Inflammatory pseudotumor of the liver is characterized by a well-circumscribed, encapsulated inflammatory mass consisting of inflammatory cell infiltration and fibrosis. We report the radiological findings of inflammatory pseudotumor of the liver in two patients with recurrent pyogenic cholangitis, showing a poorly def... | ['Aged', 'Bile Duct Neoplasms', 'Cholangiocarcinoma', 'Cholangitis', 'Cholelithiasis', 'Diagnosis, Differential', 'Granuloma, Plasma Cell', 'Humans', 'Liver Diseases', 'Male', 'Middle Aged', 'Recurrence', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 7,895,198 | [['M01.060.116.100'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['C04.557.470.200.025.450'], ['C06.130.120.200'], ['C06.130.409'], ['E01.171'], ['C23.550.382.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['M01.060.116.630'], ['C23.550.291.937'], ['E01.370.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Metformin inhibits the proliferation of hypopharyngeal carcinoma Fadu cells and enhances the chemotherapeutic sensitivity of cells]. | OBJECTIVE: To investigate the role of metformin on the growth inhibition induced by chemotherapeutic agents in hypopharyngeal carcinoma Fadu cells.METHODS: Fadu cells were treated with different concentrations of metformin for different time or treated with different concentrations of cisplatin, 5-fluorouracil or pacli... | ['AMP-Activated Protein Kinases', 'Antineoplastic Agents', 'Apoptosis', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'Cell Proliferation', 'Cisplatin', 'Cyclin-Dependent Kinase Inhibitor p21', 'Drug Screening Assays, Antitumor', 'Humans', 'Hypopharyngeal Neoplasms', 'Metformin', 'Paclitaxel'] | 24,931,021 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['D27.505.954.248'], ['G04.146.954.035'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.16... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytochemical observations on the nervous system of adult Corrigia vitta. | Adult Corrigia vitta (Trematoda: Dicrocoelidea) inhabit the pancreatic duct of the fieldmouse, Apodemus sylvaticus, where, in numbers, they may occlude the duct lumen and prevent the flow of pancreatic secretions. Enzyme histochemical and immunocytochemical techniques, in conjunction with confocal scanning laser micros... | ['Animals', 'Cholinesterases', 'FMRFamide', 'Gastrointestinal Hormones', 'Histocytochemistry', 'Immunohistochemistry', 'Lasers', 'Microscopy', 'Muridae', 'Nervous System', 'Neuropeptides', 'Neurotransmitter Agents', 'Pancreatic Polypeptide', 'Peptide YY', 'Peptides', 'Rodent Diseases', 'Serotonin', 'Substance P', 'Trem... | 7,507,138 | [['B01.050'], ['D08.811.277.352.100.170'], ['D12.644.400.235', 'D12.776.631.650.235'], ['D06.472.317'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Corticotropin and nonshivering thermogenesis. | Chronic treatment with corticotropin led to reduced calorigenic effect of norepinephrine in cold acclimatized rats, but potentiated its effect in controls. This inhibitory effect was not due to the observed decrease in corticosterone plasma level, as it was shown by metopirone administration. It is concluded that corti... | ['Acclimatization', 'Adrenocorticotropic Hormone', 'Animals', 'Body Temperature Regulation', 'Metyrapone', 'Norepinephrine', 'Rats', 'Shivering'] | 200,459 | [['G07.025.133', 'G16.012.500.133'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['D03.383.725.463']... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The genomic analysis of rubella virus detected from outbreak and sporadic cases in Rio de Janeiro state, Brazil. | BACKGROUND: The molecular epidemiology of rubella virus (RV) based on the analysis of the viral E1 gene sequences indicated the existence of two genotypes that differ from each other by 8 to 10% in their nucleotide sequences: genotype I is present in Europe, North America and Asia; and genotype II is present only in As... | ['Adolescent', 'Brazil', 'Child', 'Child, Preschool', 'Disease Outbreaks', 'Genes, Viral', 'Humans', 'Molecular Epidemiology', 'Phylogeny', 'RNA, Viral', 'Rubella', 'Rubella virus'] | 12,829,043 | [['M01.060.057'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.290'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.416', 'E05.393.522', 'H01.158.201.636.475.500', 'H01.158.273.343.595.475.500', '... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Effects of tumor necrosis factor-alpha/cachectin on thyroid hormone metabolism in mice. | To elucidate the mechanism by which low T3 and low T4 syndrome occurs in patients with acute or chronic infection or malignancy, recombinant human tumor necrosis factor-alpha (TNF-alpha)/cachectin (TNF) was administered ip to mice and thyroid hormone metabolism was studied. Since administration of TNF caused a decrease... | ['Animals', 'Body Weight', 'Dose-Response Relationship, Drug', 'Feeding Behavior', 'Humans', 'Kinetics', 'Male', 'Mice', 'Mice, Inbred ICR', 'Recombinant Proteins', 'Reference Values', 'Serum Albumin', 'Thyroid Hormones', 'Thyrotropin', 'Thyroxine', 'Triglycerides', 'Triiodothyronine', 'Triiodothyronine, Reverse', 'Tum... | 3,402,392 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.690.773.875', 'G07.690.936.500'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['B01.050.150... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A combined therapy for maxillary cancer]. | Forty-three patients with cancer of the maxillary sinus were treated by surgery combined with radiation and regional chemotherapy as a series of treatment in 1978-1989. The combined therapy consisted of the followings: 1) Operation to reduce tumor-mass. 2) Irradiation of total dose of 16 Gy, that is, 8 Gy preoperativel... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Bromodeoxyuridine', 'Combined Modality Therapy', 'Female', 'Fluorouracil', 'Humans', 'Injections, Intra-Arterial', 'Lymph Node Excision', 'Male', 'Maxillary Neoplasms', 'Middle Aged', 'Survival Rate'] | 1,888,179 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['E02.186'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.370'], ['E04.446'], ['C04.588.149.721.450.601',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The endogenous cannabinoid 2-arachidonoylglycerol is intravenously self-administered by squirrel monkeys. | Two endogenous ligands for cannabinoid CB1 receptors, anandamide (N-arachidonoylethanolamine) and 2-arachidonoylglycerol (2-AG), have been identified and characterized. 2-AG is the most prevalent endogenous cannabinoid ligand in the brain, and electrophysiological studies suggest 2-AG, rather than anandamide, is the tr... | ['Analysis of Variance', 'Animals', 'Arachidonic Acids', 'Behavior, Animal', 'Endocannabinoids', 'Extinction, Psychological', 'Glycerides', 'Infusions, Intravenous', 'Injections, Intravenous', 'Male', 'Motivation', 'Piperidines', 'Pyrazoles', 'Receptor, Cannabinoid, CB1', 'Reinforcement, Psychology', 'Rimonabant', 'Sai... | 21,562,266 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['F01.145.113'], ['D10.251.265'], ['F02.463.425.770.232'], ['D10.351'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['F01.658', 'F01.752.54... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Determination of iodide in seawater by capillary ion chromatography using hexadimethrine bromide modified C30 stationary phases. | A novel and simple capillary ion chromatographic method for the determination of iodide is reported. Separation was achieved on a laboratory-made packed capillary column (100 mm ? 0.32 mm i.d.) packed with triacontyl-functionalized silica, followed by a modification with hexadimethrine bromide, where 1 mM sodium chlor... | ['Chromatography, Liquid', 'Hexadimethrine Bromide', 'Iodides', 'Limit of Detection', 'Reproducibility of Results', 'Seawater', 'Silicon Dioxide', 'Time Factors'] | 23,303,081 | [['E05.196.181.400'], ['D02.092.782.420', 'D05.750.470', 'D25.720.470', 'J01.637.051.720.470'], ['D01.248.497.158.490', 'D01.475.410'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G16.500.275.725.500']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Interaction between aberrations to improve or reduce visual performance. | PURPOSE: To investigate how pairs of Zernike modes interact to increase or decrease visual acuity.SETTING: Visual Optics Institute, College of Optometry, University of Houston, Houston, Texas, USA.METHODS: Subjects read aberrated and unaberrated visual acuity charts 3 times. Each aberrated chart was produced by convolv... | ['Adult', 'Astigmatism', 'Humans', 'Mathematics', 'Middle Aged', 'Retina', 'Visual Acuity'] | 12,954,294 | [['M01.060.116'], ['C11.744.212'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['M01.060.116.630'], ['A09.371.729'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of the photoplethysmograph to monitor the training of a cross-leg free flap prior to division. | The cross-leg free flap is an important, although rarely used, option in the reconstruction of lower limb trauma. We report the use of photoplethysmography in the assessment of such a flap's training and the time of pedicle division. | ['Adult', 'Humans', 'Leg Injuries', 'Male', 'Neovascularization, Physiologic', 'Photoplethysmography', 'Reconstructive Surgical Procedures', 'Surgical Flaps'] | 10,927,690 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['G09.330.630'], ['E01.370.370.610.600'], ['E04.680'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of near-infrared spectroscopy during an extubation readiness trial as a predictor of extubation outcome. | OBJECTIVES: To determine whether the measurement of cerebral and somatic regional oxygen saturation during an extubation readiness trial predicts extubation failure in postoperative cardiac patients.DESIGN: Prospective observational study.SETTING: Tertiary care center cardiac ICU.PATIENTS: Pediatric patients 1 day to 2... | ['Adolescent', 'Airway Extubation', 'Cardiac Surgical Procedures', 'Child', 'Child, Preschool', 'Decision Support Techniques', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Logistic Models', 'Male', 'Outcome Assessment, Health Care', 'Oximetry', 'Postoperative Care', 'Prospective Studies', 'ROC Curve', 'Spectroscop... | 23,823,194 | [['M01.060.057'], ['E02.041.249', 'E05.008'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['M01.060.406.448'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.59... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
A Comparison of the Immunochemical Methods, PETINIA and EMIT, With That of HPLC-UV for the Routine Monitoring of Mycophenolic Acid in Heart Transplant Patients. | BACKGROUND: The aim of this study was to evaluate particle enhanced turbidimetric inhibition immunoassay (PETINIA) recently developed for mycophenolic acid (MPA) determination in plasma and to compare it with a reference high-performance liquid chromatography (HPLC) method, using samples from heart transplant recipient... | ['Adolescent', 'Adult', 'Aged', 'Chromatography, High Pressure Liquid', 'Drug Monitoring', 'Enzyme Multiplied Immunoassay Technique', 'Female', 'Heart Transplantation', 'Humans', 'Immunosuppressive Agents', 'Male', 'Middle Aged', 'Mycophenolic Acid', 'Nephelometry and Turbidimetry', 'Spectrophotometry, Ultraviolet', 'Y... | 25,380,305 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.196.181.400.300'], ['E01.370.520.200'], ['E05.478.566.350.180', 'E05.478.583.400.180', 'E05.601.470.350.180'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparative functional and physiologic status of active and dropout coronary bypass patients of a rehabilitation program. | To assess the benefits of regular participation in a medically supervised cardiac rehabilitation program, 22 patients who had undergone coronary artery bypass (2 groups of 11 each) were studied retrospectively. Group I (mean age 53 years) was currently enrolled in the rehabilitation program. Group II (mean age 56 years... | ['Adult', 'Aged', 'Coronary Artery Bypass', 'Coronary Disease', 'Evaluation Studies as Topic', 'Exercise Test', 'Exercise Therapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Dropouts', 'Patient Education as Topic', 'Retrospective Studies', 'Time Factors'] | 6,601,451 | [['M01.060.116'], ['M01.060.116.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250', 'C14.907.585.250'], ['E05.337', 'N05.715.360.335'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cross-reactivity of Rickettsia japonica and Rickettsia typhi demonstrated by immunofluorescence and Western immunoblotting. | Cross-reactivity between Rickettsia japonica and R. typhi was observed by immunofluorescence tests using sera from patients with Oriental spotted fever (OSF), from whom the causative agent was isolated and identified as R. japonica. Western immunoblotting with these sera revealed that only the 120-kilodalton surface po... | ['Antibodies, Bacterial', 'Antibody Specificity', 'Antigens, Bacterial', 'Bacterial Outer Membrane Proteins', 'Blotting, Western', 'Cross Reactions', 'Fluorescent Antibody Technique', 'Humans', 'Lipopolysaccharides', 'Rickettsia', 'Rickettsia Infections', 'Rickettsia typhi', 'Species Specificity'] | 8,789,054 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G12.100'], ['D23.050.161'], ['D12.776.097.120', 'D12.776.543.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G12.122.281'], ['E01.370.225.500.607.512.240', 'E01... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Main factors governing the transfer of carotenoids from emulsion lipid droplets to micelles. | Carotenoids might lower the incidence of several diseases, yet the mechanisms governing their intestinal absorption are still poorly understood. The aim was to identify and study the main factors governing the transfer of carotenoids from emulsion lipid droplets to mixed micelles, presumed to be a key step in carotenoi... | ['Bile', 'Carotenoids', 'Emulsions', 'Gastrointestinal Contents', 'Humans', 'Hydrogen-Ion Concentration', 'Lipids', 'Micelles', 'Water'] | 11,731,338 | [['A12.200.087'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['D20.280.260', 'D26.255.165.260'], ['A12.519'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D10'], ['D05.374', 'D26.255.560'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cerebral aneurysms: accuracy of 320-detector row nonsubtracted and subtracted volumetric CT angiography for diagnosis. | PURPOSE: To assess the accuracy of 320-detector row nonsubtracted and subtracted volumetric computed tomographic (CT) angiography for detection of cerebral aneurysms.MATERIALS AND METHODS: After institutional review board approval and informed written consent were obtained, 282 consecutive patients suspected of having ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angiography, Digital Subtraction', 'Cerebral Angiography', 'Contrast Media', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Intracranial Aneurysm', 'Iohexol', 'Male', 'Middle Aged', 'Sensitivity and Specificity'] | 24,009,353 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Reaction-based genetically encoded fluorescent hydrogen sulfide sensors. | The detection of hydrogen sulfide (H(2)S), a toxic gas and an important biological signaling molecule, has been a long-time challenge. Here we report genetically encoded fluorescent protein (FP)-based probes that can selectively detect H(2)S. By expanding the genetic codes of E. coli and mammalian cells, FP chromophore... | ['Animals', 'Azides', 'Biosensing Techniques', 'Escherichia coli', 'Fluorescent Dyes', 'Gene Expression', 'Green Fluorescent Proteins', 'HeLa Cells', 'Humans', 'Hydrogen Sulfide', 'Models, Molecular', 'Oxidation-Reduction'] | 22,642,566 | [['B01.050'], ['D01.625.100', 'D02.159'], ['E05.601.043'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G05.297'], ['D12.776.532.265'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The radical transbasal approach for resection of anterior and midline skull base lesions. | OBJECT: Craniofacial surgery can be performed to treat midline and anterior skull base lesions by creating a bicoronal scalp incision without the need for an additional transfacial procedure. Originally described as the transbasal approach, several modifications for further exposure of the skull base have been describe... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Craniotomy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nasal Cavity', 'Neurosurgical Procedures', 'Orbit', 'Postoperative Complications', 'Retrospective Studies', 'Skull Base', 'Skull Base Neoplasms', 'Treatment Outcome'] | 16,235,681 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['E04.525.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A04.531.449'], ['E04.525'], ['A02.835.232.781.324.690'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Catecholamine-producing tumors]. | We report 93 patients with catecholamine producing tumors that were analyzed at the Hormone Laboratory of the Institute of Cardiology. They are 75 pheochromocytoma patients and 18 children with neuroblastoma. Fluorimetric methods were used to measure urinary and plasma catecholamines on neuroblastoma and pheochromocyto... | ['Adolescent', 'Adrenal Gland Neoplasms', 'Adult', 'Catecholamines', 'Child', 'Dopamine', 'Epinephrine', 'Female', 'Fluorometry', 'Humans', 'Male', 'Middle Aged', 'Neuroblastoma', 'Norepinephrine', 'Pheochromocytoma'] | 1,793,308 | [['M01.060.057'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['M01.060.406'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A combined liquid three-phase micro-extraction and differential pulse voltammetric method for preconcentration and detection of ultra-trace amounts of buprenorphine using a modified pencil electrode. | A combination of polytetrafluorethylene membrane-based liquid three-phase micro-extraction and voltammetry was used for the micro-separation and determination of buprenorphine. Type of the organic solvent used, pH levels of the donor and acceptor phases, salt concentration, extraction time, stirring rate, and electroch... | ['Buprenorphine', 'Calibration', 'Electrochemical Techniques', 'Electrodes', 'Graphite', 'Humans', 'Hydrogen-Ion Concentration', 'Limit of Detection', 'Liquid Phase Microextraction', 'Membranes, Artificial', 'Morphine Dependence', 'Narcotics', 'Polytetrafluoroethylene', 'Sodium Chloride', 'Solvents'] | 24,148,523 | [['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['E05.978.155'], ['E05.301'], ['E07.305.250'], ['D01.268.150.300', 'D01.578.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Is heart rate variability an objective parameter with which to manage treatment of infants with heart failure due to left-to-right shunting? | Treatment in heart failure could be guided by additional non-clinical measures, such as neurohumoral levels. Variability in heart rate is known to reflect neurohumoral stimulation. With this in mind, we sought to assess retrospectively the variability in heart rate to guide the treatment of infants in heart failure. We... | ['Heart Failure', 'Heart Rate', 'Humans', 'Infant', 'Infant, Newborn', 'Parasympathetic Nervous System', 'Retrospective Studies', 'Weight Gain'] | 15,831,154 | [['C14.280.434'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A08.800.050.600'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sodium in smooth muscle relaxation. | The contraction of guinea-pig taenia coli due to high K+ could not be reversed by washing when Na+ was absent from the medium. Reintroduction of Na+ (7 mM or more) caused relaxation. Similar results were obtained with rat uterus. The effect of sodium replacement was not due to change in ionic strength because equal or ... | ['Animals', 'Calcium', 'Choline', 'Colon', 'Guinea Pigs', 'In Vitro Techniques', 'Lanthanum', 'Magnesium', 'Manganese', 'Muscle Contraction', 'Muscle, Smooth', 'Potassium', 'Sodium'] | 835,696 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['B01.050.150.900.649.313.992.550'], ['E05.481'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['D01.268.552.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of cytogenetic microarrays in myelodysplastic syndrome characterization. | Various microarray platforms, including BAC, oligonucleotide, and SNP arrays, have been shown to -provide clinically useful diagnostic and prognostic information for patients with myelodysplastic syndromes (MDS). Clinically useful arrays are designed with specific purposes in mind and with attention to genomic content ... | ['Animals', 'Comparative Genomic Hybridization', 'Humans', 'Myelodysplastic Syndromes', 'Oligonucleotide Array Sequence Analysis', 'Polymorphism, Single Nucleotide'] | 23,412,784 | [['B01.050'], ['E05.393.285.240', 'E05.393.520.500', 'E05.393.661.187'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.190.625'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['G05.365.795.598']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Probability of viral labeling of neural stem cells in vivo. | In the neuroscience field over the past several decades, viral vectors have become powerful gene delivery systems to study neural populations of interest. For neural stem cell (NSC) biology, such viruses are often used to birth-date and track NSCs over developmental time in lineage tracing experiments. Yet, the probabi... | ['Animals', 'Gene Transfer Techniques', 'Hippocampus', 'Lentivirus', 'Neural Stem Cells', 'Retroviridae', 'Staining and Labeling'] | 29,777,716 | [['B01.050'], ['E05.393.350'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B04.820.650.589'], ['A11.872.653'], ['B04.613.807', 'B04.820.650'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine. | The development of fluorescent biolabels for specific targeting and controlled drug release is of paramount importance in biological applications due to their potential in the generation of novel tools for simultaneous diagnosis and treatment of diseases. Dopamine is a neurotransmitter involved in several neurological ... | ['Attention Deficit Disorder with Hyperactivity', 'Cadmium', 'Cadmium Compounds', 'Cell Line, Tumor', 'Dopamine', 'Dopamine Agents', 'Drug Delivery Systems', 'Fluorescent Dyes', 'Glucose Transporter Type 1', 'Humans', 'Parkinson Disease', 'Polyethylene Glycols', 'Quantum Dots', 'Selenium', 'Staining and Labeling', 'Sul... | 22,037,807 | [['F03.625.094.150'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.142'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['E02.319.300'], ['D27.720.233.348', 'D27.720.470.410.5... | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
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