Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Preparation, structure, and electrochemistry of a polypyrrole film doped with manganese(III)-substituted Dawson-type phosphopolyoxotungstate. | The fabrication, structure, electrochemical properties, and electrocatalytic properties of a manganese(III)-substituted Dawson-type phosphopolyoxotungstate, alpha 2-K7P2W17O61(Mn3+.OH2).12H2O (P2W17Mn), entrapped in polypyrrole (PPy) film have been studied. The hybrid film was prepared by potentiostatic polymerization ... | ['Anions', 'Biophysics', 'Catalysis', 'Chemistry, Physical', 'Electrochemistry', 'Hydrogen Peroxide', 'Hydrogen-Ion Concentration', 'Manganese', 'Molecular Conformation', 'Nitrites', 'Pyrroles', 'Spectrophotometry, Ultraviolet', 'Spectrum Analysis, Raman', 'Tungsten Compounds', 'Ultraviolet Rays'] | 16,851,272 | [['D01.248.497.158'], ['H01.158.344', 'H01.671.100'], ['G02.130'], ['H01.181.529'], ['H01.181.529.307'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G02.300'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['G02.111.570.820'], ['D01.248.497.158.635', ... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The immunogenicity of a modified intradermal pre-exposure rabies vaccination schedule--a case series of 420 travelers. | BACKGROUND: Current Australian recommendations for rabies pre-exposure vaccination involve the use of cell-culture-based rabies vaccines, which are administered via intramuscular (IM) or intradermal (ID) routes. ID vaccination is more affordable for travelers, but is only recommended if there is sufficient time to perf... | ['Adolescent', 'Adult', 'Aged', 'Australia', 'Child', 'Female', 'Humans', 'Immunization Schedule', 'Immunogenetics', 'Injections, Intradermal', 'Male', 'Middle Aged', 'Prognosis', 'Rabies', 'Rabies Vaccines', 'Retrospective Studies', 'Travel', 'Vaccination', 'Young Adult'] | 21,896,096 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.470', 'E05.478.550.545'], ['H01.158.273.343.420'], ['E02.319.267.530.620.410'], ['M01.060.116.630'], ['E01.789'], ['C01.925.782.580.830.750'... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles targeting Clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo C. difficile infection model. | Clostridioides (formerly Clostridium) difficile is a Gram-positive anaerobic bacterial pathogen that causes severe gastrointestinal infection in humans. The current chemotherapeutic options are vastly inadequate, expensive and limited; this results in an exorbitant medical and financial burden. New, inexpensive chemoth... | ['Animals', 'Anti-Bacterial Agents', 'Cations', 'Clostridioides difficile', 'Clostridium Infections', 'Humans', 'Male', 'Mice, Inbred C57BL', 'Microbial Sensitivity Tests', 'Peptidomimetics', 'Triazoles'] | 30,901,686 | [['B01.050'], ['D27.505.954.122.085'], ['D01.248.497.300'], ['B03.353.625.657.500'], ['C01.150.252.410.222'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D27.505.519.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of interoceptive awareness on functional connectivity in patients with irritable bowel syndrome. | Irritable bowel syndrome (IBS) is characterized by visceral hypersensitivity likely related to altered processing of sensory stimuli along the brain-gut axis. Previous neuroimaging studies demonstrated structural and functional alteration of several brain areas involved in bodily representation, e.g. the insula, in pat... | ['Adult', 'Aged', 'Awareness', 'Brain', 'Brain Mapping', 'Female', 'Humans', 'Interoception', 'Irritable Bowel Syndrome', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neural Pathways', 'Neuropsychological Tests', 'Surveys and Questionnaires', 'Young Adult'] | 27,704,405 | [['M01.060.116'], ['M01.060.116.100'], ['F02.463.188.150'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.465'], ['C06.405.469.158.272.608'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A08.612'], ['F04.711.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subcutaneous use of a fast-acting insulin analog: an alternative treatment for pediatric patients with diabetic ketoacidosis. | OBJECTIVE: To look for technical simplification and economic efficiency in the treatment of pediatric diabetic ketoacidosis (DKA) with subcutaneous use of the fast-acting insulin analog (lispro) and compare its use with regular intravenous insulin treatment.RESEARCH DESIGN AND METHODS: In this controlled clinical trial... | ['Blood Glucose', 'Child', 'Diabetes Mellitus, Type 1', 'Diabetic Ketoacidosis', 'Female', 'Humans', 'Hypoglycemic Agents', 'Injections, Subcutaneous', 'Insulin', 'Insulin Lispro', 'Male', 'Patient Compliance'] | 16,043,723 | [['D09.947.875.359.448.500'], ['M01.060.406'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['E02.319.267.530.620'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Predictors of adherence to occlusion therapy 3 months after cataract extraction in the Infant Aphakia Treatment Study. | BACKGROUND: Little information is available on factors that predict adherence to patching in infants. We evaluated data from the Infant Aphakia Treatment Study, a randomized clinical trial of treatment for infants with unilateral congenital cataracts, to investigate factors associated with successful adherence to patch... | ['Amblyopia', 'Aphakia, Postcataract', 'Caregivers', 'Cataract', 'Cataract Extraction', 'Contact Lenses', 'Female', 'Humans', 'Infant', 'Lens Implantation, Intraocular', 'Male', 'Patient Compliance', 'Sensory Deprivation', 'Surveys and Questionnaires', 'Visual Acuity'] | 22,525,171 | [['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['C11.510.103.110'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['C11.510.245'], ['E04.540.825.249'], ['E07.632.500.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E04.540.825.600'], ['F01.100.150.750.5... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vivo and in vitro effects of microRNA-27a on proliferation, migration and invasion of breast cancer cells through targeting of SFRP1 gene via Wnt/â-catenin signaling pathway. | This study aims to explore the effects of microRNA-27a (miR-27a) targeting of SFRP1 on the proliferation, migration and invasion of breast cancer (BC) cells through the regulation of Wnt/â-catenin signaling pathway. BC and normal breast tissues were obtained from 396 female BC patients and 308 female patients with beni... | ["3' Untranslated Regions", 'Adult', 'Aged', 'Aged, 80 and over', 'Blotting, Western', 'Breast Neoplasms', 'Cell Line', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Female', 'Gene Expression Regulation, Neoplastic', 'Glycogen Synthase Kinase 3 beta', 'Humans', 'Intercellular Signaling Peptides and Protei... | 28,099,945 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.180', 'C17.800.090.500'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chromosome localization of the genes for isocitrate dehydrogenase-1, isocitrate dehydrogenase-2, glutathione reductase, and phosphoglycerate kinase-1 in the American mink (Mustela vison). | Twenty-eight hybrid clones with different mink chromosomes were derived from the fusion of Chinese hamster and American mink (mustela vison) cells. This set of clones made it possible to assign the mink genes for isocitrate dehydrogenase-1 (soluble) to chromosome 4, for isocitrate dehydrogenase-2 (mitochrondrial) to ch... | ['Animals', 'Chromosome Mapping', 'Cricetinae', 'Cricetulus', 'Fibroblasts', 'Glutathione Reductase', 'Hybrid Cells', 'Isocitrate Dehydrogenase', 'Isoenzymes', 'Mink', 'Phosphoglycerate Kinase'] | 7,128,216 | [['B01.050'], ['E05.393.183'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['A11.329.228'], ['D08.811.682.667.092'], ['A11.251.600'], ['D08.811.682.047.820.475'], ['D08.811.348', 'D12.776.800.300'], ['B01.050.150.900.649.313.750.250.575.500'], ['D08.811.913.696.630.700'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vascular renin-angiotensin: a possible autocrine or paracrine system in control of vascular function. | Circulating angiotensin influences vascular tone via its receptors particularly at the precapillary vessels. In addition, an intrinsic renin-angiotensin system has been postulated to exist in vascular wall. In this study, we documented components of the renin-angiotensin system in cultured vascular smooth-muscle cells.... | ['Angiotensin I', 'Angiotensin II', 'Angiotensinogen', 'Animals', 'Cells, Cultured', 'Dogs', 'Hydrogen-Ion Concentration', 'Kinetics', 'Muscle, Smooth, Vascular', 'Renin', 'Renin-Angiotensin System'] | 6,206,346 | [['D06.472.699.094.075', 'D12.644.400.070.075', 'D12.644.456.073.021', 'D12.644.548.058.075', 'D12.776.631.650.070.075', 'D23.469.050.050.025'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D12.644.456.073.070', 'D12.64... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolomic analysis of the plasma of patients with high-altitude pulmonary edema (HAPE) using 1H NMR. | Upon rapid ascent to a high altitude, non-acclimatized individuals, although healthy, are highly prone to contracting high-altitude pulmonary edema (HAPE). Early diagnosis is difficult and there is no reliable biomarker available. We used proton ((1)H) NMR metabolomics to profile the altered metabolic patterns of blood... | ['Adult', 'Altitude Sickness', 'Amino Acids', 'Blood Glucose', 'Case-Control Studies', 'Humans', 'Hypertension, Pulmonary', 'Least-Squares Analysis', 'Lipoproteins', 'Male', 'Metabolomics', 'Nuclear Magnetic Resonance, Biomolecular', 'Plasma', 'Principal Component Analysis'] | 22,498,880 | [['M01.060.116'], ['C08.618.020'], ['D12.125'], ['D09.947.875.359.448.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The shell region of the nucleus ovoidalis: a subdivision of the avian auditory thalamus. | The connectivity of a region surrounding the established thalamic auditory nuclei, n. ovoidalis (Ov) and n. semilunaris parovoidalis (SPO), was explored in the ring dove by using the anterograde tracers, Phaseolus vulgaris leucoagglutinin (PHAL) and biocytin, and the retrograde tracer, fluorogold. The Ov-SPO surround r... | ['Acoustic Stimulation', 'Animals', 'Auditory Pathways', 'Columbidae', 'Electrophysiology', 'Female', 'Fluorescent Dyes', 'Hearing', 'Histocytochemistry', 'Hypothalamus', 'Lysine', 'Male', 'Phytohemagglutinins', 'Stilbamidines', 'Thalamic Nuclei'] | 1,430,319 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['A08.612.220.110'], ['B01.050.150.900.248.165.150'], ['H01.158.344.528', 'H01.158.782.236'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.60... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Production of platelet-activating factor by washed rabbit platelets. | Production of platelet-activating factor by washed rabbit platelets under stimulation with the ionophore A23187 was investigated utilizing two groups of platelet preparations. The first platelet preparation contained 0.03 +/- 0.02% contaminating white cells, while the second preparation contained 0.48 +/- 0.27% white c... | ['Animals', 'Blood Platelets', 'Calcimycin', 'Leukocyte Count', 'Male', 'Phospholipids', 'Platelet Activating Factor', 'Rabbits'] | 3,934,305 | [['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['D03.633.100.221.173'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105.595'], ['D10.570.755'], ['D02.033.100.291.211.500', 'D02.092.063.291.211.500', 'D... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ADHD and working memory: the impact of central executive deficits and exceeding storage/rehearsal capacity on observed inattentive behavior. | Inattentive behavior is considered a core and pervasive feature of ADHD; however, an alternative model challenges this premise and hypothesizes a functional relationship between working memory deficits and inattentive behavior. The current study investigated whether inattentive behavior in children with ADHD is functio... | ['Analysis of Variance', 'Attention', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child Behavior', 'Diagnostic and Statistical Manual of Mental Disorders', 'Executive Function', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Models, Psychological', 'Neuropsychological Tests', 'Psychomotor Performance... | 19,787,447 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.104.214'], ['F03.625.094.150'], ['M01.060.406'], ['F01.145.179'], ['L01.453.245.945.200'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['E05.599.695'], ['F04.711.513'], ['F02.808', 'G11.427.700',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Effects of salinomycin on human bone marrow-derived mesenchymal stem cells in vitro. | Various hypotheses on the origin of cancer stem cells (CSCs) exist, including that CSCs develop from transformed human bone marrow mesenchymal stem cells (hBMSC). Since the polyether antibiotic salinomycin selectively kills CSCs, the present study aims to elucidate the effects of salinomycin on normal hBMSC. The immuno... | ['Bone Marrow Cells', 'Cell Differentiation', 'Cell Line', 'Cell Movement', 'Cell Shape', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Flow Cytometry', 'Humans', 'Immunophenotyping', 'Mesenchymal Stem Cells', 'Pyrans'] | 23,410,960 | [['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['G04.320'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of the inhibitor complexes of cobalt carboxypeptidase A by electron paramagnetic resonance spectroscopy. | The metal coordination sphere of cobalt-substituted carboxypeptidase A and its complexes with inhibitors has been characterized by X-band electron paramagnetic resonance (EPR) spectroscopy. The temperature dependence of the EPR spectrum of cobalt carboxypeptidase and the g anisotropy are consistent with a distorted tet... | ['Carboxypeptidases', 'Carboxypeptidases A', 'Cobalt', 'Computer Simulation', 'Electron Spin Resonance Spectroscopy', 'Kinetics', 'Ligands', 'Protein Binding', 'Structure-Activity Relationship'] | 2,541,781 | [['D08.811.277.656.350.245'], ['D08.811.277.656.350.245.250', 'D08.811.277.656.350.555.350', 'D08.811.277.656.675.555.350'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['L01.224.160'], ['E05.196.867.519.274'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['G02.111.679', 'G03.808'], ['G02.111.830... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Isolated ventral pancreatitis in an alcoholic with pancreas divisum. | An alcoholic with no history of clinical pancreatitis was found to have pancreas divisum and marked changes of chronic pancreatitis isolated to the ventral pancreas. Pancreas divisum has been suggested to cause recurrent pancreatitis in some patients. Gross and histologic changes of pancreatitis in only the dorsal panc... | ['Adult', 'Alcoholism', 'Cholangiopancreatography, Endoscopic Retrograde', 'Chronic Disease', 'Humans', 'Male', 'Pancreas', 'Pancreatitis', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 3,049,209 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.734'], ['C06.689.750'], ['E01.370.350.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antimicrobial electrospun ultrafine fibers from zein containing eucalyptus essential oil/cyclodextrin inclusion complex. | The aim of this study was to produce ultrafine fibers from zein incorporated with a complex of eucalyptus essential oil (EEO) and â-cyclodextrin (â-CD) with antimicrobial properties by electrospinning technique. The EEO was characterized by chemical composition and antimicrobial tests against three Gram positive and fo... | ['Anti-Infective Agents', 'Electricity', 'Eucalyptus', 'Listeria monocytogenes', 'Membranes, Artificial', 'Microbial Sensitivity Tests', 'Oils, Volatile', 'Staphylococcus aureus', 'Zein', 'beta-Cyclodextrins'] | 28,652,153 | [['D27.505.954.122'], ['G01.358.500.249'], ['B01.650.940.800.575.912.250.773.366'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D10.627.675'], ['B03.300.390.400.800.750.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Bacteriophage lambda cro mutations: effects on activity and intracellular degradation. | Following random mutagenesis of the bacteriophage lambda cro gene, we have isolated missense mutations that affect approximately half of the 66 residue positions of Cro. About two-thirds of the mutations change residues involved in the maintenance of Cro structure and stability. The corresponding mutant proteins are se... | ['Amino Acid Sequence', 'Bacteriophage lambda', 'DNA-Binding Proteins', 'Mutation', 'Promoter Regions, Genetic', 'Protein Biosynthesis', 'Protein Conformation', 'Repressor Proteins', 'Structure-Activity Relationship', 'Transcription Factors', 'Viral Proteins', 'Viral Regulatory and Accessory Proteins'] | 2,947,238 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['D12.776.260'], ['G05.365.590'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['G02.111.570.820.709'], ['D12.776.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
ATM influences the efficiency of TCRâ rearrangement, subsequent TCRâ-dependent T cell development, and generation of the pre-selection TCRâ CDR3 repertoire. | Generation and resolution of DNA double-strand breaks is required to assemble antigen-specific receptors from the genes encoding V, D, and J gene segments during recombination. The present report investigates the requirement for ataxia telangiectasia-mutated (ATM) kinase, a component of DNA double-strand break repair, ... | ['Animals', 'Ataxia Telangiectasia Mutated Proteins', 'Cell Division', 'Cell Line', 'Cell Survival', 'Complementarity Determining Regions', 'DNA Breaks, Double-Stranded', 'Gene Order', 'Gene Rearrangement, beta-Chain T-Cell Antigen Receptor', 'Mice', 'Mice, Knockout', 'Receptors, Antigen, T-Cell, alpha-beta', 'T-Lympho... | 23,626,787 | [['B01.050'], ['D08.811.913.696.620.682.700.097', 'D12.776.157.687.125', 'D12.776.660.720.125'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['G04.346'], ['D12.644.541.500.650.500.180', 'D12.776.124.486.485.680.650.500.180', 'D12.776.124.486.485.797.180', 'D12.776.124.790.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The validity of self-report weight and height as a surrogate method for direct measurement. | Bland-Altman analysis used to determine the extent of bias, agreement, and precision between self-report and the "gold standard" of actual weight and height measurement revealed significant discrepancies between methods. Use of self-report data by health care providers and researchers should be made based on the clinic... | ['Adolescent', 'African Americans', 'Analysis of Variance', 'Bias', 'Body Height', 'Body Mass Index', 'Body Weight', 'Female', 'Humans', 'Reproducibility of Results', 'Self Report'] | 20,974,100 | [['M01.060.057'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['N05.715.350.150', 'N06.850.490.500'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prolonged postsynaptic changes in the sensorimotor cortex of the awake rabbit in response to stimulation of fibers of the white matter of the new cortex and the corpus callosum. | The postsynaptic changes in the focal potentials of the sensorimotor cortex of the awake rabbit was investigated in this study following tetanization of the corpus callosum and the white matter. Stimulation of these structures was carried out during testing. A prolonged (hour-long) increase in the amplitude of the resp... | ['Animals', 'Corpus Callosum', 'Electric Stimulation', 'Electrodes, Implanted', 'Motor Cortex', 'Nerve Fibers', 'Neuronal Plasticity', 'Rabbits', 'Somatosensory Cortex', 'Synapses'] | 8,332,241 | [['B01.050'], ['A08.186.211.200.885.800.750'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['A08.675.542', 'A11.671.501'], ['G11.561.638'], ['B01.050.150.900.649.313.968.700'], ['A08.186.211.200.885.287.500.670.675', 'A08.186.211.2... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term outcome of treating rheumatoid arthritis: results after 20 years. | Outcome of therapy, in terms of functional capacity, radiological measures of joint damage, erythrocyte sedimentation rate (ESR), rheumatoid factor, and mortality, was determined prospectively in 112 consecutive rheumatoid arthritis (RA) patients treated for 20 years at one centre, where a policy of active treatment wa... | ['Adult', 'Arthritis, Rheumatoid', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Prognosis'] | 2,883,443 | [['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hydrogen-bonding interactions in 2-thiophen-3-ylmalonic acid. | Formation of intra- and intermolecular hydrogen bonds in 2-thiophen-3-ylmalonic acid, the precursor of a polythiophene derivative bearing two carboxylic acid groups in the side chain, have been examined by Fourier transform infrared (FTIR) spectroscopy and ab initio quantum mechanical calculations. Interactions found i... | ['Computer Simulation', 'Hydrogen Bonding', 'Malonates', 'Models, Chemical', 'Molecular Conformation', 'Quantum Theory', 'Spectroscopy, Fourier Transform Infrared', 'Thermodynamics', 'Thiophenes'] | 18,821,743 | [['L01.224.160'], ['G02.282'], ['D02.241.081.337.540'], ['E05.599.495'], ['G02.111.570.820'], ['H01.671.579.800'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['G01.906'], ['D02.886.778', 'D03.383.903']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
A Diagnostic Accuracy Meta-analysis of CT and MRI for the Evaluation of Small Bowel Crohn Disease. | RATIONALE AND OBJECTIVES: This study aimed to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT) in assessing small bowel (SB) Crohn disease (CD).MATERIALS AND METHODS: We systematically searched PubMed, Elsevier, ScienceDirect, Karger, Web of Science, Wiley Online Library... | ['Crohn Disease', 'Humans', 'Intestine, Small', 'Magnetic Resonance Imaging', 'ROC Curve', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed'] | 28,595,876 | [['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684'], ['E01.370.350.825.500'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', '... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Renal nerves are not necessary for onset or maintenance of DOC-salt hypertension in rats. | The effect of renal denervation on the onset and maintenance of mineralocorticoid-salt [deoxycorticosterone (DOC)-salt] hypertension was determined. A unilateral right nephrectomy was performed on all rats. Rats were divided into renal-denervated and sham-operated groups. All rats received 10 mg/wk of DOC pivalate and ... | ['Animals', 'Blood Pressure', 'Body Weight', 'Denervation', 'Desoxycorticosterone', 'Hypertension', 'Kidney', 'Male', 'Norepinephrine', 'Rats', 'Rats, Inbred Strains', 'Sodium Chloride', 'Tail'] | 4,061,671 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E04.525.210'], ['D04.210.500.745.745.654.339', 'D06.472.040.585.611'], ['C14.907.489'], ['A05.810.453'], ['D02.033.100.291.502', 'D02.092.063.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[How to reduce maternal mortality?]. | Maternal mortality is still very high in developing countries. A large proportion of maternal deaths are due to delayed or substandard emergency obstetric care. There is an urgent need to develop and validate interventions designed to improve the management of obstetric complications. There is some experimental or quas... | ['Female', 'Humans', 'Maternal Mortality', 'Pregnancy', 'Pregnancy Complications', "Women's Health Services"] | 24,313,010 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.500', 'N01.224.935.698.653', 'N06.850.505.400.975.550.500', 'N06.850.520.308.985.550.500'], ['G08.686.784.769'], ['C13.703'], ['N02.421.920']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Application of high frequency color Doppler ultrasound in anterolateral thigh flap surgery]. | OBJECTIVE: To investigate the effectiveness of high frequency color Doppler ultrasound for detecting perforators in the anterolateral thigh (ALT) flap surgery.METHODS: Between February 2011 and July 2012, 8 patients underwent high frequency color Doppler ultrasound to detect the perforator anatomy before ALT flap surge... | ['Adult', 'Carcinoma, Squamous Cell', 'Female', 'Follow-Up Studies', 'Graft Survival', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Preoperative Care', 'Scalp', 'Skin', 'Skin Transplantation', 'Soft Tissue Injuries', 'Surgical Flaps', 'Thigh', 'Ultrasonography, Doppler, Color', 'Young Adult'] | 23,596,685 | [['M01.060.116'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.340'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795'], ['A0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tangential breast irradiation with or without internal mammary chain irradiation: results of a randomized trial. | UNLABELLED: A prospective randomized study was made of 270 patients with unilateral stage I or II invasive breast cancer treated by segmental resection, axillary dissection and radiation at the University Hospital of Tampere, Finland, between 1989 and 1991. The aim of the study was to determine whether there is any adv... | ['Breast Neoplasms', 'Combined Modality Therapy', 'Female', 'Humans', 'Lung Diseases', 'Lymphatic Irradiation', 'Middle Aged', 'Prospective Studies', 'Radiation Injuries', 'Radiodermatitis', 'Radiotherapy'] | 8,532,902 | [['C04.588.180', 'C17.800.090.500'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['E02.815.350'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gas chromatographic analysis of fosfomycin in plasma for pharmacokinetic analysis. | An efficient method for gas chromatographic analysis of fosfomycin in plasma was developed for preliminary investigations of the bioavailability in poultry of 3 commercial complexes of fosfomycin: a levorotatory Ca(-) salt, a racemic Ca(+/-) salt, and a tromethamine (THAM) salt. The method was used to determine whether... | ['Animals', 'Anti-Bacterial Agents', 'Biological Availability', 'Calcium', 'Chickens', 'Chromatography, Gas', 'Fosfomycin', 'Sensitivity and Specificity', 'Therapeutic Equivalency', 'Tromethamine'] | 10,367,380 | [['B01.050'], ['D27.505.954.122.085'], ['G03.787.151', 'G07.690.725.129'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.349'], ['D02.705.429.625'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.36... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sexual behaviour change associated with a college HIV course. | This study examined the effects of a multidisciplinary, multi-media college course, The HIV Pandemic and AIDS, on the knowledge, attitudes and behaviours of students. A quasi-experimental design was implemented using pre- and post-questionnaires administered to students enrolled in the course and to two control groups ... | ['Adult', 'Behavior Therapy', 'Curriculum', 'Female', 'HIV Infections', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Sexual Behavior', 'Surveys and Questionnaires', 'Universities', 'Young Adult'] | 26,665,918 | [['M01.060.116'], ['F04.754.137'], ['I02.158'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.802'], ['E05.318.308.980', 'N05.715.360.300.800',... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Alloxan-induced diabetes exacerbates coronary atherosclerosis and calcification in Ossabaw miniature swine with metabolic syndrome. | BACKGROUND: There is a preponderance of evidence implicating diabetes with increased coronary artery disease (CAD) and calcification (CAC) in human patients with metabolic syndrome (MetS), but the effect of diabetes on CAD severity in animal models remains controversial. We investigated whether diabetes exacerbates CAD... | ['Animals', 'Blood Glucose', 'Calcinosis', 'Calcium', 'Calcium Channels', 'Cardiomyopathies', 'Coronary Artery Disease', 'Diabetes Mellitus, Experimental', 'Disease Progression', 'Glucose Tolerance Test', 'Insulin', 'Insulin-Secreting Cells', 'Metabolic Syndrome', 'Muscle, Smooth', 'Severity of Illness Index', 'Swine',... | 29,523,165 | [['B01.050'], ['D09.947.875.359.448.500'], ['C18.452.174.130'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['C14.280.238'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C18.452.394.750.074', 'C19.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A novel SRY gene mutation c.266 A>T (p.E89V) in a 46,XY complete gonadal dysgenesis patient. | The SRY gene is considered as the key player in the male sexual differentiation and developmental pathway. SRY gene mutations account for ~15% of 46,XY disorders of sexual development patients, and majority of them resides within the HMG domain of the protein. In this study, we report a novel missense mutation within t... | ['Adolescent', 'Amino Acid Substitution', 'DNA Mutational Analysis', 'Gonadal Dysgenesis, 46,XY', 'Humans', 'Male', 'Point Mutation', 'Sex-Determining Region Y Protein'] | 31,361,042 | [['M01.060.057'], ['E05.393.420.601.035', 'G05.558.109'], ['E05.393.760.700.300'], ['C12.706.316.096.687', 'C12.706.316.309.388', 'C13.351.875.253.096.687', 'C13.351.875.253.309.388', 'C16.131.939.316.096.687', 'C16.131.939.316.309.388', 'C19.391.119.096.687', 'C19.391.119.309.388'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The tomato SlWRKY gene plays an important role in the regulation of defense responses in tobacco. | WRKY-type transcription factors are involved in multiple aspects of plant growth, development and stress responses. SlWRKY, a cDNA clone encoding a polypeptide of 552 amino acids and exhibiting the structural features of group I of WRKY protein family, was isolated from tomato (Solanum lycopersicum L. cv Zhongshu No. 4... | ['Amino Acid Sequence', 'Droughts', 'Genes, Plant', 'Lycopersicon esculentum', 'Molecular Sequence Data', 'Plants, Genetically Modified', 'Salt Tolerance', 'Stress, Physiological', 'Tobacco', 'Transcription Factors'] | 23,036,198 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['B01.650.940.800.575.912.250.908.500.322'], ['L01.453.245.667'], ['B01.650.520', 'B05.620.600'], ['G07.025.133.250', 'G07.775.813.500', 'G16.012.500.133.25... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Structural and biological characterization of Nattectin, a new C-type lectin from the venomous fish Thalassophryne nattereri. | Lectins are glycan-binding receptors that recognize glycan epitopes on foreign pathogens and in the host systems. They can be involved in functions that include innate immunity, development, immune regulation and homeostasis. Several lectins have been purified and characterized from fish species. In this work, using ca... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Batrachoidiformes', 'Binding Sites', 'Calcium', 'Cell Movement', 'Conserved Sequence', 'Fish Venoms', 'Galactose', 'Hemagglutination Tests', 'Hindlimb', 'Humans', 'Immunity, Innate', 'Immunologic Factors', 'Inflammation', 'Lectins, C-Type', 'Leukocytes', 'Matrix Meta... | 21,396,978 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.493.039'], ['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.198', 'G07.568.500.180'], ['G02.111.570.580'], ['D20.888.370', 'D23.946.580.370', 'D23.946.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The organization, control and coordination of measures for localization and liquidation of mass poultry loss and prevention of human diseases caused by avian flu in Ordynsk area of Novosibirsk region]. | Materials on the organization, the control and to coordination of actions of services in carrying out of actions on localization and liquidation of the centers of a mass destruction of birds and preventive measures of people diseases by avian flu during the period from July, 21 till September, 18, 2005 are submitted. T... | ['Adolescent', 'Adult', 'Animals', 'Birds', 'Child', 'Diagnosis, Differential', 'Disease Outbreaks', 'Disease Reservoirs', 'Disinfection', 'Humans', 'Influenza Vaccines', 'Orthomyxoviridae Infections', 'Poultry', 'Poultry Diseases', 'Practice Guidelines as Topic', 'Quarantine', 'Siberia', 'Vaccination', 'Zoonoses'] | 16,981,501 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['B01.050.150.900.248'], ['M01.060.406'], ['E01.171'], ['N06.850.290'], ['N06.850.520.203.250'], ['N06.850.780.200.450.850.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['C01.925.782.620'], ['B01.050.050.116.625', 'B01.050.150.900.248.69... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Renal failure and progressive pancytopenia. | Hyperparathyroidism may be a precipitating factor to the development of myelofibrosis; however, this is extremely rare with only a few documented case reports of myelofibrosis caused by secondary hyperparathyroidism. We describe a case of a 24-year-old female who had a failed live donor renal transplant and secondary h... | ['Bone Marrow', 'Female', 'Fibrosis', 'Humans', 'Hyperparathyroidism, Secondary', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Pancytopenia', 'Renal Dialysis', 'Young Adult'] | 30,488,885 | [['A15.382.216'], ['C23.550.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355.480'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['C15.378.700'], ['E02.870.300', 'E02.912.800'], ['M01.060.116.815']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A possible virus aetiology in outbreaks of food-poisoning from cockles. | In a series of outbreaks of food-poisoning associated with the consumption of cockles, no bacterial pathogens were demonstrable either in faeces of patients or in cockles. However, small round virus-like particles have been detected in a high proportion of the faecal specimens in three of the outbreaks. These particles... | ['Cesium', 'Disease Outbreaks', 'England', 'Feces', 'Foodborne Diseases', 'Humans', 'Microscopy, Electron', 'Mollusca', 'Shellfish Poisoning', 'Viruses, Unclassified'] | 66,573 | [['D01.268.549.125', 'D01.268.556.165', 'D01.552.528.160', 'D01.552.544.165'], ['N06.850.290'], ['Z01.542.363.300'], ['A12.459'], ['C25.723.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.050.500.644'], ['C25.723.415.792'], ['B04.970']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Incidence and determinants of stillbirth among women who gave birth in Jimma University specialized hospital, Ethiopia. | Introduction: Worldwide approximately 2.7 million are stillborn, more than 98% of these occur in developing countries. To address the problem, incidence and determinants of stillbirth must be understood. Therefore the aim of this study was to assess incidence and determinants of stillbirth among women who gave birth in... | ['Adult', 'Cross-Sectional Studies', 'Delivery, Obstetric', 'Ethiopia', 'Female', 'Health Services Accessibility', 'Hospitals, University', 'Humans', 'Incidence', 'Logistic Models', 'Middle Aged', 'Pregnancy', 'Prenatal Care', 'Referral and Consultation', 'Stillbirth', 'Surveys and Questionnaires', 'Time Factors', 'You... | 29,721,130 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E04.520.252'], ['Z01.058.290.120.310'], ['N04.590.374.350', 'N05.300.430'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Overexpression of the human 72 kDa heat shock protein in renal tubular cells confers resistance against oxidative injury and cisplatin toxicity. | BACKGROUND: Recent studies have shown that the 72-kDa heat shock protein (HSP72) can be induced in renal tubular cells by a variety of stress conditions, and suggested its cytoprotective function. We have tested this hypothesis directly by transfection studies.METHODS: LLC-PK1 cells (porcine renal tubular epithelial ce... | ['Animals', 'Antineoplastic Agents', 'Cells, Cultured', 'Cisplatin', 'HSP72 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Humans', 'Hydrogen Peroxide', 'Kidney Tubules', 'Oxidative Stress', 'Swine'] | 10,382,997 | [['B01.050'], ['D27.505.954.248'], ['A11.251'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D12.776.580.216.375.202'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['A05.810.453.736.560'], ['G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluating the relationship between carisoprodol concentrations and meprobamate formation and inter-subject and intra-subject variability in urinary excretion data of pain patients. | Using urinary carisoprodol data from pain patients, our objectives were to determine the relationship between carisoprodol concentration and its conversion to meprobamate, and quantify the intra-subject and inter-subject variability in carisoprodol metabolism. Liquid chromatography-tandem mass spectrometry was used to ... | ['Carisoprodol', 'Chromatography, High Pressure Liquid', 'Chronic Pain', 'Drug Monitoring', 'Female', 'Humans', 'Male', 'Meprobamate', 'Models, Biological', 'Muscle Relaxants, Central', 'Reference Values', 'Reproducibility of Results', 'Tandem Mass Spectrometry', 'Urinalysis'] | 22,511,696 | [['D02.241.081.251.165'], ['E05.196.181.400.300'], ['C23.888.592.612.274'], ['E01.370.520.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.081.251.510'], ['E05.599.395'], ['D27.505.696.510', 'D27.505.696.663.700.600', 'D27.505.954.427.525'], ['E05.978.810'], ['E05.318.370.725', 'E05.337.851', 'N05.715.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Recurrent Cerebral Hemorrhage in Normal Pregnancy Secondary to Mycotic Pseudoaneurysms Related to Choriocarcinoma. | BACKGROUND: Choriocarcinoma coexisting with or after normal pregnancy is extremely rare. To our knowledge, our case report is the first time cerebral mycotic pseudoaneurysms from choriocarcinoma have been proven angiographically.CASE DESCRIPTION: A 38-week pregnant 26-year-old woman presented with an acute left frontal... | ['Adult', 'Aneurysm, False', 'Angiography, Digital Subtraction', 'Cerebral Angiography', 'Cerebral Hemorrhage', 'Choriocarcinoma', 'Female', 'Humans', 'Intracranial Aneurysm', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Recurrence', 'Uterine Neoplasms'] | 28,987,845 | [['M01.060.116'], ['C14.907.055.090'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changing bone marrow micro-environment during development of acute myeloid leukaemia in rats. | The Brown Norwegian rat transplanted with promyelocytic leukaemic cells (BNML) has been used as a model for human acute myeloid leukaemia. We have previously shown that both the blood supply to the bone marrow and the metabolic rate decrease in relation to the leukaemic development in these rats. Here we have investiga... | ['Acute Disease', 'Animals', 'Body Weight', 'Bone Marrow', 'Cell Cycle', 'Hematopoiesis', 'Hydrogen-Ion Concentration', 'Leukemia, Myeloid', 'Leukemia, Promyelocytic, Acute', 'Leukocyte Count', 'Liver', 'Male', 'Neoplasm Seeding', 'Nitroimidazoles', 'Organ Size', 'Oxygen Consumption', 'Radiation-Sensitizing Agents', 'R... | 9,695,960 | [['C23.550.291.125'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A15.382.216'], ['G04.144'], ['G04.152.825', 'G09.188.343'], ['G02.300'], ['C04.557.337.539'], ['C04.557.337.539.275.700'], ['E01.370.225.500.195.107.595', 'E01.370.22... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Bacteriological sensitivity "in vitro" and therapeutic response (author's transl)]. | After some general considerations on the validity of antibiograms as a therapeutic guide, three methods are described and analyzed. Bacterial chemosensitivity to antimicrobic drugs were tested by the following methods: diffusion, dilution and automized methods. Only when transferred into routine laboratory methods that... | ['Anti-Bacterial Agents', 'Bacteria', 'Bacterial Infections', 'Blood-Brain Barrier', 'Drug Resistance, Microbial', 'Female', 'Humans', 'Maternal-Fetal Exchange', 'Microbial Sensitivity Tests', 'Pregnancy', 'Tissue Distribution'] | 555,523 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Profiling of the bacteria responsible for pyogenic liver abscess by 16S rRNA gene pyrosequencing. | Pyogenic liver abscess (PLA) is a severe disease with considerable mortality and is often polymicrobial. Understanding the pathogens that cause PLA is the basis for PLA treatment. Here, we profiled the bacterial composition in PLA fluid by pyrosequencing the 16S ribosomal RNA (rRNA) gene based on next-generation sequen... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bacteria', 'Female', 'Humans', 'Liver Abscess, Pyogenic', 'Male', 'Middle Aged', 'RNA, Ribosomal, 16S'] | 24,871,976 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.830.025.020.455.730', 'C06.552.597.758'], ['M01.060.116.630'], ['D13.444.735.686.670']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sex and PRNP genotype determination in preimplantation caprine embryos. | The objective of this study was to test the accuracy of genotype diagnosis after whole amplification of DNA extracted from biopsies obtained by trimming goat embryos and to evaluate the viability of biopsied embryos after vitrification/warming and transfer. Whole genome amplification (WGA) was performed using Multiple ... | ['Animals', 'Blastocyst', 'DNA', 'Embryo Transfer', 'Female', 'Genome', 'Genotype', 'Goats', 'Male', 'Pregnancy', 'Pregnancy Rate', 'Prions', 'Sex Determination Analysis'] | 21,121,967 | [['B01.050'], ['A16.254.500'], ['D13.444.308'], ['E02.875.800.500', 'E05.820.800.500'], ['G05.360.340'], ['G05.380'], ['B01.050.150.900.649.313.500.380.513'], ['G08.686.784.769'], ['E05.318.308.985.775', 'G08.686.705', 'N01.224.935.849', 'N06.850.505.400.975.775', 'N06.850.520.308.985.775'], ['D12.776.785'], ['E01.370.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cardiopulmonary Bypass Increases Plasma Glial Fibrillary Acidic Protein Only in First Stage Palliation of Hypoplastic Left Heart Syndrome. | BACKGROUND: Univentricular congenital heart defects require open-heart surgery soon after birth, and are associated with risk of brain injury and poor neurologic outcome.METHODS: This is a prospective, observational study on children undergoing cardiac surgery. Plasma glial fibrillary acidic protein (GFAP), as an early... | ['Biomarkers', 'Cardiac Surgical Procedures', 'Cardiopulmonary Bypass', 'Child, Preschool', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Follow-Up Studies', 'Glial Fibrillary Acidic Protein', 'Humans', 'Hypoplastic Left Heart Syndrome', 'Infant', 'Infant, Newborn', 'Italy', 'Male', 'Palliative Care', 'Prognosis', 'P... | 26,481,085 | [['D23.101'], ['E04.100.376', 'E04.928.220'], ['E04.292.413'], ['M01.060.406.448'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D05.750.078.593.400', 'D12... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Response of Soil Microbes to Vegetation Restoration in Coal Mining Subsidence Areas at Huaibei Coal Mine, China. | Vegetation restoration is an available way to ameliorate degraded lands. In order to study the response of soil microbes to vegetation restoration in coal mining subsidence areas, the composition and distribution of soil microbes were discussed through three plots: unsubsided area (CA), new subsided area (NSA), and old... | ['Bacteria', 'China', 'Coal Mining', 'Environmental Restoration and Remediation', 'Fungi', 'Nitrogen', 'Phosphorus', 'Soil', 'Soil Microbiology'] | 31,108,967 | [['B03'], ['Z01.252.474.164'], ['J01.576.655.875.500.500'], ['N06.230.080.600', 'N06.850.460.375'], ['B01.300'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Expression of serum BMP6 and hepcidin in cancer-related anemia. | Objective: To study the function of human bone morphogenetic protein-6 (BMP6) and hepcidin in cancer-related anemia.Methods: The levels of Hemoglobin (Hb), serum C-reactive protein (CRP), BMP6, hepcidin and ferritin (SF) were measured in 115 patients with solid tumors, who were divided into elevated CRP group and norma... | ['Aged', 'Anemia', 'Bone Morphogenetic Protein 6', 'Female', 'Hepcidins', 'Humans', 'Male', 'Neoplasms'] | 32,153,255 | [['M01.060.116.100'], ['C15.378.071'], ['D12.644.276.954.200.600', 'D12.776.467.942.200.600', 'D23.529.942.200.600'], ['D12.776.494.249', 'D12.776.543.695.054.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cytosolic and mitochondrial Ca2+ | Mitochondrial Ca2+ flux is crucial for the regulation of cell metabolism. Ca2+ entry to the mitochondrial matrix is mediated by VDAC1 and MCU with its regulatory molecules. We investigated hepatocytes isolated from conplastic C57BL/6NTac-mtNODLtJ mice (mtNOD) that differ from C57BL/6NTac mice (controls) by a point muta... | ['Adaptation, Biological', 'Aging', 'Animals', 'Calcium', 'Calcium Channels', 'Calcium Signaling', 'Calcium-Binding Proteins', 'Cells, Cultured', 'Cytosol', 'DNA, Mitochondrial', 'Electron Transport Complex IV', 'Glucose', 'Hepatocytes', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Mitochondrial Membrane Transpor... | 31,377,553 | [['G16.012'], ['G07.345.124'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D12.776.157.125'], ['A11.251'], ['A11.284.430.214.200', 'A11.284.430.429.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dose rate effect of gamma irradiation on phenolic compounds, polyphenol oxidase, and browning of mushrooms (Agaricus bisporus). | To enhance the shelf life of edible mature mushrooms, Agaricus bisporus, 2 kGy ionizing treatments were applied at two different dose rates: 4.5 kGy/h (I(-)) and 32 kGy/h (I(+)). Both I(+) and I(-) showed a 2 and 4 day shelf-life enhancement compared to the control (C). Before day 9, no significant difference (p>0.05) ... | ['Agaricales', 'Catechol Oxidase', 'Colorimetry', 'Dose-Response Relationship, Radiation', 'Gamma Rays', 'Maillard Reaction', 'Phenols'] | 10,552,523 | [['B01.300.179.100'], ['D08.811.682.690.708.125'], ['E05.196.922.250'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['G02.607.522'], ['D02.455.426.559.389.657']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Simultaneous dissolution profiles of two drugs in pharmaceutical formulations by an FIA manifold. | This article deals with the simultaneous determination of dissolution profiles of two drugs with overlapped spectra, present in the same pharmaceutical formulation. The official procedure for the dissolution profile is adapted to the continuous-flow methodology; the dissolution vessel is connected to an FIA manifold, i... | ['Anti-Infective Agents', 'Flow Injection Analysis', 'Solubility', 'Sulfamethoxazole', 'Trimethoprim'] | 11,836,065 | [['D27.505.954.122'], ['E05.196.460'], ['G02.805'], ['D02.065.884.725.867', 'D02.092.146.807.867', 'D02.886.590.700.725.867'], ['D03.383.742.906']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hedgehog signalling is required for cell survival in Drosophila wing pouch cells. | An appropriate balance between cell survival and cell death is essential for correct pattern formation in the animal tissues and organs. Previous studies have shown that the short-range signalling molecule Hedgehog (Hh) is required for cell proliferation and pattern formation in the Drosophila central wing discs. Signa... | ['Animals', 'Apoptosis', 'Biomarkers', 'Cell Survival', 'Drosophila', 'Drosophila Proteins', 'Fluorescent Antibody Technique', 'Gene Expression', 'Genes, Reporter', 'Hedgehog Proteins', 'JNK Mitogen-Activated Protein Kinases', 'RNA Interference', 'Signal Transduction', 'Wings, Animal'] | 28,900,135 | [['B01.050'], ['G04.146.954.035'], ['D23.101'], ['G04.346'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['G05.297'], ['G05.360.340.024.340.435'], ['D12.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nutritional Assessment of Dialysis Patient with a Web-Based Tool Allows More Accurate Treatment of Malnutrition. | BACKGROUND/AIMS: Regular assessment of nutritional status of dialysis patients is vital for preventing malnutrition and protein energy wasting. The aim of this clinical study was to analyze dietary intake of dialysis patients and to determine if it meets their nutritional needs.METHODS: Clinical study was conducted on ... | ['Body Composition', 'Electric Impedance', 'Energy Intake', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nutrition Assessment', 'Nutritional Status', 'Protein-Energy Malnutrition', 'Renal Dialysis', 'Reproducibility of Results', 'Retrospective Studies'] | 30,864,367 | [['G02.111.130', 'G03.180', 'G07.100.049'], ['G01.358.500.249.277.350'], ['G07.203.650.240.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.585', 'N05.715.360.300.560', 'N06.850.505.557', 'N06.850.520.308.585'], ['G07.203.650.650', 'N01.224.425.525'], ['C18.654.521.500.708.626'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transcriptomic analysis of the impacts of ethinylestradiol (EE2) and its consequences for proliferative kidney disease outcome in rainbow trout (Oncorhynchus mykiss). | Freshwater fish are threatened by the cumulative impact of multiple stressors. The purpose of this study was to unravel the molecular and organism level reactions of rainbow trout, Oncorhynchus mykiss, to the combined impact of two such stressors that occur in the natural habitat of salmonids. Fish were infected with e... | ['Animals', 'Ethinyl Estradiol', 'Fish Diseases', 'Gene Expression Regulation', 'Kidney Diseases', 'Myxozoa', 'Oncorhynchus mykiss', 'Parasitic Diseases, Animal', 'Transcriptome'] | 31,004,835 | [['B01.050'], ['D04.210.500.668.651.568.291', 'D06.472.334.851.437.968.500'], ['C22.362'], ['G05.308'], ['C12.777.419', 'C13.351.968.419'], ['B01.050.500.308.550'], ['B01.050.150.900.493.817.750.825.580.600'], ['C01.610.701', 'C22.674'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A record of procedures--its use and usefulness. Evaluation of a tool for general practitioners in Telemark]. | A loose-leaf book of procedures has been published earlier. The aim of this evaluation was to study the use of this book in the county of Telemark, and the possible effect of the book on the quality of the letters notifying admission to hospital. A questionnaire has been sent twice to all general practitioners in Telem... | ['Diagnosis', 'Evaluation Studies as Topic', 'Family Practice', 'Manuals as Topic', 'Medical Records', 'Norway', 'Therapeutics'] | 1,412,242 | [['E01'], ['E05.337', 'N05.715.360.335'], ['H02.403.340.500'], ['L01.178.682.192.609', 'L01.178.820.500'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500', 'N06.850.520.308.940.968'], ['Z01.542.816.374'], ['E02']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
A study of physician attitude on biofeedback. | A study of physician attitudes on biofeedback was conducted among members of the Harris County Medical Society, Harris County, Texas. The sample was drawn to match the proportionate representation in the society by speciality. Findings indicated that over 62% of the respondents had little knowledge of biofeedback, over... | ['Attitude of Health Personnel', 'Biofeedback, Psychology', 'Epilepsy', 'Fecal Incontinence', 'Headache', 'Humans', 'Hypertension', 'Medicine', 'Neuromuscular Diseases', 'Pain, Intractable', 'Raynaud Disease', 'Referral and Consultation', 'Relaxation Therapy', 'Specialization'] | 7,046,812 | [['F01.100.050', 'N05.300.100'], ['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['C10.228.140.490'], ['C06.405.469.860.300'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['H02.403'], ['C10.668'], ['C23.888.592.612.776'], ['C14.907.617.812'], ['N0... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme. | Haptoglobin (Hp) is the plasma protein that binds and clears cell-free hemoglobin (Hb), whereas apohemoglobin (apoHb, i.e., Hb devoid of heme) can bind heme. Therefore, the apoHb-Hp protein complex should facilitate holoHb-apoHb áâ-dimer exchange and apoHb-heme intercalation. Thus, we hypothesized that apoHb-Hp could f... | ['Animals', 'Apoproteins', 'Blood Transfusion', 'Cricetinae', 'Guinea Pigs', 'Haptoglobins', 'Heme', 'Hemoglobins', 'Humans', 'Hypertension', 'Male', 'Mesocricetus', 'Microcirculation', 'Protein Binding', 'Vasoconstriction'] | 32,302,494 | [['B01.050'], ['D12.776.070'], ['E02.095.135'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.550'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anteromedial versus central single-bundle graft position: which anatomic graft position to choose? | PURPOSE: To compare the time-zero stability of an anatomic anteromedial (AM) single-bundle ACL reconstruction to an anatomic central (CTR) single-bundle ACL reconstruction.METHODS: Twelve (6 paired) hip to knee cadaveric specimens were studied. Using custom ACL computer navigation software, a Lachman test and a previou... | ['Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Reconstruction', 'Biomechanical Phenomena', 'Cadaver', 'Humans', 'Knee Joint', 'Menisci, Tibial', 'Tendons'] | 22,057,352 | [['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['E04.555.110.026', 'E04.680.101.026'], ['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['A02.165.308.538.500', 'A02.835.583.475.590', 'A10.165.382.350.163.500'], ['A02.880']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reiter's syndrome in uremia: report of a case. | A 35-year-old male uremic patient developed the classical presentation of Reiter's syndrome after 3 years of regular hemodialysis. He had painful swelling of the left knee, sacroilitis, urethritis, balanitis, painless oral ulcers, acute uveitis and positive HLA-B27. Disease activity persisted and was aggravated althoug... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Arthritis, Reactive', 'Humans', 'Immune Tolerance', 'Male', 'Uremia'] | 2,769,218 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['C01.100.500', 'C05.116.900.853.625.800.637', 'C05.550.114.099.500', 'C05.550.114.865.800.637'], ['B01.050.150.900.649.313.988.400.112... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mammalian sperm contain a Ca(2+)-sensitive phospholipase C activity that can generate InsP(3) from PIP(2) associated with intracellular organelles. | We have previously described a phospholipase C (PLC) activity in mammalian sperm cytosolic extracts. Here we have examined the Ca(2+) dependency of the enzyme, whether there is enough in a single sperm to account for Ca(2+) release at fertilization, and finally where in the egg is the phosphatidyl 4,5-bisphosphate, the... | ['Aniline Compounds', 'Animals', 'Biological Factors', 'Calcium', 'Calcium Signaling', 'Cell Extracts', 'Cell Fractionation', 'Dose-Response Relationship, Drug', 'Inositol 1,4,5-Trisphosphate', 'Male', 'Microscopy, Electron', 'Oocytes', 'Organelles', 'Phosphatidylinositol 4,5-Diphosphate', 'Sea Urchins', 'Spermatozoa',... | 11,087,632 | [['D02.092.146'], ['B01.050'], ['D23'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D20.777.162'], ['E05.242.251'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.800.519.400.350', 'D09.853.519.400.350', 'D09.894.480.350'], ['E01.370.350.515... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of impaired testosterone metabolism during prenatal ontogenesis on the level of anxiety and behavior of rats in a novel environment. | The effects of administration of the aromatase inhibitor 1,4,6-androstatrien-3.17-dione (ATD) to female rats during the last third of pregnancy on the formation of behavior of offspring of both genders in a novel environment were studied. Animal behavior was assessed in the open field and elevated cross maze tests. Inh... | ['Androstatrienes', 'Animals', 'Anxiety', 'Aromatase Inhibitors', 'Brain', 'Emotions', 'Exploratory Behavior', 'Female', 'Male', 'Organogenesis', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Rats, Wistar', 'Sex Differentiation', 'Sex Factors', 'Testosterone'] | 17,505,792 | [['D04.210.500.054.079.229'], ['B01.050'], ['F01.470.132'], ['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['A08.186.211'], ['F01.470'], ['F01.145.387', 'F01.658.370'], ['G07.345.500.325.377', 'G08.686.784.170.450'], ['G08.686.784.769'], ['C13.703.824.500'], ['B01.050.150.900... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Endocytic pathway is required for Drosophila Toll innate immune signaling. | The Toll signaling pathway is required for the innate immune response against fungi and Gram-positive bacteria in Drosophila. Here we show that the endosomal proteins Myopic (Mop) and Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) are required for the activation of the Toll signaling pathway. This r... | ['Animals', 'Cell Line', 'Drosophila Proteins', 'Drosophila melanogaster', 'Endocytosis', 'Endosomal Sorting Complexes Required for Transport', 'Immunity, Innate', 'Phosphoproteins', 'Protein Tyrosine Phosphatases', 'RNA Interference', 'Signal Transduction', 'Toll-Like Receptors'] | 20,404,143 | [['B01.050'], ['A11.251.210'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G04.417'], ['D05.500.199', 'D12.776.543.990.493'], ['G12.450.564'], ['D12.776.744'], ['D08.811.277.352.650.775'], ['G05.308.203.374.790'], ['G02.111.820', 'G04.835'], ['D12.776.543.750.705.910.500']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Putative glucosensing property in rat and human activated microglia. | Microglial cells involved in the pathogenesis of many neurodegenerative diseases acquire the features of cytotoxic and phagocytic cells in response to certain pathogens and inflammatory signals. K(ATP) channels are energy sensors of ATP availability that link the cell's metabolic state to its membrane excitability. In ... | ['Aged', 'Aged, 80 and over', 'Animals', 'Cerebral Cortex', 'Glucokinase', 'Glucose', 'Humans', 'Male', 'Microglia', 'Neurodegenerative Diseases', 'Potassium Channels', 'Rats', 'Rats, Sprague-Dawley'] | 15,350,960 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['D08.811.913.696.620.250'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.637.400', 'A11.650.400'], ['C10.574'], ['D12.776.157.530.400.600', 'D12.776.543.550.450.750', 'D12.776.543.585.400.750... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence and Risk Factors for Rectal and Urethral Sexually Transmitted Infections From Self-Collected Samples Among Young Men Who Have Sex With Men Participating in the Keep It Up! 2.0 Randomized Controlled Trial. | BACKGROUND: Despite recommendations that sexually active men who have sex with men be regularly tested for sexually transmitted infections (STIs) and that testing reflect anatomical sites of potential exposure, regular testing is not widely performed, especially for rectal STIs. As such, little is known about the preva... | ['Adolescent', 'Adult', 'Chlamydia Infections', 'Gonorrhea', 'HIV Infections', 'Humans', 'Male', 'Prevalence', 'Rectal Diseases', 'Rectum', 'Risk Factors', 'Sexually Transmitted Diseases', 'Specimen Handling', 'Urethra', 'Urethral Diseases', 'Young Adult'] | 28,703,727 | [['M01.060.057'], ['M01.060.116'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['C01.150.252.400.625.275', 'C01.150.252.734.401', 'C01.221.812.281.401', 'C01.778.281.401', 'C12.294.668.281.401', 'C13.351.500.711.281.401'... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mechanical signaling in a pulmonary microvascular endothelial cell monolayer. | The mechanical microenvironment of an endothelial cell includes a stable protein scaffold on the basal side, flowing blood on the apical side and contractile cells on the lateral sides. Interaction with the protein scaffold and flowing blood modulates the ability of endothelial cells to migrate, align and maintain barr... | ['Animals', 'Cells, Cultured', 'Endothelial Cells', 'Lung', 'Neovascularization, Physiologic', 'Rats', 'Signal Transduction', 'Stress, Mechanical'] | 31,514,994 | [['B01.050'], ['A11.251'], ['A11.436.275'], ['A04.411'], ['G09.330.630'], ['B01.050.150.900.649.313.992.635.505.700'], ['G02.111.820', 'G04.835'], ['G01.374.835']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ornithine decarboxylase activity of L929 cells after exposure to continuous wave or 50 Hz modulated radiofrequency radiation--a replication study. | A replication study with some extensions was made to confirm enhancement of ornithine decarboxylase (ODC) activity in murine L929 fibroblasts after radiofrequency (RF) field exposure reported in earlier studies. L929 cells purchased from two cell banks were exposed for 2, 8, or 24 h to continuous wave or DAMPS (burst m... | ['Animals', 'Cell Line', 'Dose-Response Relationship, Radiation', 'Electricity', 'Environmental Exposure', 'Enzyme Activation', 'Fibroblasts', 'Gene Expression Regulation, Enzymologic', 'Mice', 'Ornithine Decarboxylase', 'Radiation Dosage', 'Radio Waves', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 17,508,405 | [['B01.050'], ['A11.251.210'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['G01.358.500.249'], ['N06.850.460.350'], ['G02.111.263', 'G03.328'], ['A11.329.228'], ['G05.308.320'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.520.224.125.425'], ['E05.7... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Improving needle visualization by novice residents during an in-plane ultrasound nerve block simulation using an in-plane multiangle needle guide. | OBJECTIVE: Ultrasound-guided regional anesthesia with in-plane needle approaches can be challenging due to difficult needle visualization. We hypothesized that an in-plane, multiangle needle guide can help reduce the time it takes novice regional anesthesiologists to perform a simulated ultrasound-guided nerve-targetin... | ['Adult', 'Anesthesiology', 'Female', 'Humans', 'Internship and Residency', 'Male', 'Needles', 'Nerve Block', 'Ultrasonography, Interventional'] | 23,758,955 | [['M01.060.116'], ['H02.403.066'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['E07.612'], ['E03.155.086.711', 'E04.525.210.550'], ['E01.370.350.850.855', 'E04.502.890']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Effects of transportation on early embryonic death in mares. | Incidence of early embryonic death (EED) and associated changes in serum cortisol, progesterone and plasma ascorbic acid (AA) in transported mares were investigated. Mares were transported for 472 km (9 h) during either d 16 to 22 (T-3 wk, n = 15) or d 32 to 38 (T-5 wk, n = 15) of gestation. Blood samples were drawn fr... | ['Animals', 'Ascorbic Acid', 'Female', 'Fetal Death', 'Horse Diseases', 'Horses', 'Hydrocortisone', 'Pregnancy', 'Progesterone', 'Stress, Physiological', 'Transportation'] | 2,312,427 | [['B01.050'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['C13.703.223', 'C23.550.260.585'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['G08.686.784.769'], ['D04.210.500.745.745.654.829', 'D06.472.334.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials. | Cangrelor is an intravenous antagonist of the P2Y(12) receptor characterized by rapid, potent, predictable, and reversible platelet inhibition. However, cangrelor was not superior to clopidogrel in reducing the incidence of ischemic events in the cangrelor versus standard therapy to achieve optimal management of platel... | ['Adenosine Monophosphate', 'Aged', 'Angioplasty, Balloon, Coronary', 'Clopidogrel', 'Drug Antagonism', 'Humans', 'Male', 'Middle Aged', 'Platelet Aggregation', 'Platelet Function Tests', 'Preoperative Care', 'Prospective Studies', 'Purinergic P2Y Receptor Antagonists', 'Receptors, Purinergic P2Y12', 'Ticlopidine'] | 22,569,899 | [['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['D02.886.778.823... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased cerebellar volume in the early stage of fucosidosis: a case control study. | INTRODUCTION: Yet unreported in this lysosomal storage disease, we aimed to quantify our observation that patients with fucosidosis may show abnormally increased cerebellar volumes during early childhood.METHODS: Five normocephalic fucosidosis patients (age range 2-25 months, three males) were included in this retrospe... | ['Case-Control Studies', 'Cerebellum', 'Child, Preschool', 'Female', 'Fucosidosis', 'Humans', 'Imaging, Three-Dimensional', 'Infant', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Organ Size', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 21,384,124 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A08.186.211.132.810.428.200'], ['M01.060.406.448'], ['C10.228.140.163.100.435.295', 'C16.320.565.189.435.295', 'C16.320.565.202.303', 'C16.320.565.595.554.295', 'C18.452.132.100.435.295', 'C18.452.648.189.435.295', 'C18.452.648.202.303', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Practical legal and ethical considerations for the provision of acute disaster mental health services. | Mental health professionals who provide emergency psychosocial assistance in the immediate aftermath of disasters do so in the midst of crisis and chaos. Common roles undertaken by disaster mental health professionals include treating existing conditions of disaster survivors and providing psychosocial support to front... | ['Clinical Competence', 'Codes of Ethics', 'Confidentiality', 'Disasters', 'Emergency Medical Services', 'Evidence-Based Practice', 'Guidelines as Topic', 'Humans', 'Interprofessional Relations', 'Liability, Legal', 'Licensure', 'Mental Health Services', 'Patient Care Team', 'Physician-Patient Relations', 'Professional... | 23,244,009 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['K01.752.566.479.068', 'K01.752.566.479.171.066', 'N04.761.700.350.324', 'N05.350.213', 'N05.350.340.080', 'N05.700.350.324'], ['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['N06.230.100'], ['N02.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Head waving in Aplysia californica. II. Functional anatomy and muscular activity during behaviour. | Bending and twisting movements of the body during head-waving behaviour of the sea hare Aplysia californica are produced by the concerted action of the muscles of the body wall on the hydrostatic skeleton formed by the haemocoel and internal organs. In this study, we describe the orientations and possible mechanical ac... | ['Animals', 'Aplysia', 'Behavior, Animal', 'Electromyography', 'Head', 'Histocytochemistry', 'Hydrostatic Pressure', 'Motor Activity', 'Movement', 'Muscles'] | 7,964,419 | [['B01.050'], ['B01.050.500.644.400.060'], ['F01.145.113'], ['E01.370.405.255', 'E01.370.530.255'], ['A01.456'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['G01.374.715.352'], ['F01.145.632', 'G11.427.410.698'], ['G... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Primary malignant lymphoma of the rectum--a case report]. | The patient was a 69-year-old woman who complained of bloody stools and abdominal pain. A tumor was removed with abdominoperineal excision, and histologic examination revealed malignant lymphoma associated with reactive lymphoreticular hyperplasia. The lesion was of the diffuse, medium-sized cell type according to the ... | ['Aged', 'Colostomy', 'Female', 'Humans', 'Lymphoma', 'Prognosis', 'Rectal Neoplasms'] | 3,712,777 | [['M01.060.116.100'], ['E04.210.338.225', 'E04.579.338.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['E01.789'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.405.469.491.307.790', 'C06.405.469.860.180.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intrathecal morphine for intractable pain secondary to cancer of pelvic organs. | Sixty-two patients with intractable pain secondary to cancer of the pelvic organs were managed with intrathecal injections of morphine. Forty-six patients experienced pain relief from an initial test dose that ranged from 0.5 to 2.0 mg. In order to provide long-term pain relief, these 46 patients were further treated w... | ['Humans', 'Injections, Spinal', 'Morphine', 'Pain, Intractable', 'Pelvic Neoplasms'] | 3,838,582 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.580'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['C23.888.592.612.776'], ['C04.588.699']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Redundancy in ascending and descending pathways mediating head turning elicited by entopenducular stimulation in the cat. | Contraversive turning movements of the head were elicited in alert cats by unilateral electrical stimulation of the entopeduncular nucleus. To determine the relative functional importance of ascending and descending pathways activated by the stimulation, the animals were submitted to thalamocortical or midbrain lesions... | ['Afferent Pathways', 'Animals', 'Efferent Pathways', 'Electric Stimulation', 'Female', 'Globus Pallidus', 'Head', 'Male', 'Movement'] | 6,646,420 | [['A08.612.220'], ['B01.050'], ['A08.612.380'], ['E05.723.402'], ['A08.186.211.200.885.287.249.487.397'], ['A01.456'], ['G07.568', 'G11.427.410']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural Articulation of Biochemical Reactions Using Restrained Geometries and Topology Switching. | A strategy named "restrained geometries and topology switching" (RGATS) is presented to obtain detailed trajectories for complex biochemical reactions using molecular mechanics (MM) methods. It enables prediction of realistic dynamical pathways for chemical reactions, especially for accurately characterizing the struct... | ['Ammonium Compounds', 'Biochemical Phenomena', 'Catalytic Domain', 'DNA-Directed DNA Polymerase', 'Histidine', 'Imidazoles', 'Lipid Bilayers', 'Magnesium', 'Models, Chemical', 'Nucleotides', 'Protons', 'Quantum Theory', 'Software'] | 29,357,231 | [['D01.625.062'], ['G02.111'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D08.811.913.696.445.308.300'], ['D12.125.072.329', 'D12.125.142.308'], ['D03.383.129.308'], ['D10.570.510', 'J01.637.087.500.510'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E05.599.495'], ['D09.408.620', 'D1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Prevalence of antibiotic resistance genes and bacterial pathogens in long-term manured greenhouse soils as revealed by metagenomic survey. | Antibiotic resistance genes (ARGs), human pathogenic bacteria (HPB), and HPB carrying ARGs pose a high risk to soil ecology and public health. Here, we used a metagenomic approach to investigate their diversity and abundance in chicken manures and greenhouse soils collected from Guli, Pulangke, and Hushu vegetable base... | ['Animals', 'Bacteria', 'Chickens', 'China', 'DNA', 'Drug Resistance, Microbial', 'Genes, Bacterial', 'Manure', 'Metagenomics', 'RNA, Ribosomal, 16S', 'Soil', 'Soil Microbiology', 'Tetracycline Resistance'] | 25,514,174 | [['B01.050'], ['B03'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['Z01.252.474.164'], ['D13.444.308'], ['G06.225', 'G07.690.773.984.269'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['D20.601'], ['H01.158.273.343.350.261'], ['D13.444.735.686.670'], ['D20... | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
The role of membrane structure in the activation of mitochondrial phospholipases. 1. Activation of mitochondrial phospholipases by lipid peroxidation products. | Induction of lipid peroxidation is shown to alter the structure of mitochondrial membrane and to activate endogenous phospholipases A2, C, D, and lysophospholipase A. Fe(2+)-, cumene hydroperoxide- and ultraviolet-induced lipid peroxidation results in the activation of mitochondrial phospholipases. | ['Animals', 'Ascorbic Acid', 'Benzene Derivatives', 'Calcium', 'Electron Spin Resonance Spectroscopy', 'Enzyme Activation', 'Intracellular Membranes', 'Isoenzymes', 'Lipid Peroxidation', 'Membrane Lipids', 'Membrane Proteins', 'Mitochondria, Liver', 'Oxidants', 'Phospholipases', 'Phospholipids', 'Rats', 'Ultraviolet Ra... | 9,829,257 | [['B01.050'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D02.455.426.559.389'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.196.867.519.274'], ['G02.111.263', 'G03.328'], ['A11.284.149.450', 'A11.284.835.514'], ['D08.811.348', 'D12.776.800.300'], ['G02.111.515', 'G03.295.531.587']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Variable effects of dispersal on productivity of bacterial communities due to changes in functional trait composition. | Previous studies have shown variable relationships between dispersal rate and ecosystem functioning, but the reasons for and mechanisms behind variable dispersal rate-functioning patterns are currently unknown. In this study we used six bacterial lake water communities in a laboratory experiment in order to investigate... | ['Adaptation, Physiological', 'Bacterial Proteins', 'Biodiversity', 'Coumaric Acids', 'Ecosystem', 'Lakes', 'Leucine', 'Microbial Consortia', 'Phylogeny', 'Propionates', 'RNA, Ribosomal, 16S', 'Regression Analysis', 'Tritium', 'Water Microbiology'] | 24,324,633 | [['G07.025', 'G16.012.500'], ['D12.776.097'], ['G16.500.275.157.049', 'N06.230.124.049'], ['D02.241.223.200.210'], ['G16.500.275.157', 'N06.230.124'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D12.125.070.637', 'D12.125.142.441'], ['G06.591.750', 'G16.500.275.157.049.100.500.750', 'N06.230.124.049.10... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Biomechanical and morphometric properties of the arterial wall referenced to the zero-stress state in experimental diabetes. | Morphometric and passive biomechanical properties were studied in isolated segments of the thoracic and abdominal aorta, left common carotid artery, left femoral artery and the left pulmonary artery in 20 non-diabetic and 28 streptozotocin (STZ)-induced diabetic rats. The diabetic and non-diabetic rats were divided int... | ['Animals', 'Arteries', 'Biomechanical Phenomena', 'Blood Glucose', 'Blood Pressure', 'Body Weight', 'Diabetes Mellitus, Experimental', 'Diabetic Angiopathies', 'Male', 'Rats', 'Rats, Wistar', 'Stress, Mechanical'] | 11,204,544 | [['B01.050'], ['A07.015.114'], ['G01.154.090', 'G01.374.089'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C14.90... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrostatic redesign of the [myoglobin, cytochrome b5] interface to create a well-defined docked complex with rapid interprotein electron transfer. | Cyt b(5) is the electron-carrier "repair" protein that reduces met-Mb and met-Hb to their O(2)-carrying ferroheme forms. Studies of electron transfer (ET) between Mb and cyt b(5) revealed that they react on a "Dynamic Docking" (DD) energy landscape on which binding and reactivity are uncoupled: binding is weak and invo... | ['Computer Simulation', 'Cytochromes b5', 'Kinetics', 'Models, Molecular', 'Myoglobin', 'Protein Binding', 'Static Electricity', 'Thermodynamics'] | 19,419,145 | [['L01.224.160'], ['D08.244.187.500', 'D12.776.422.220.187.500'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['G02.111.679', 'G03.808'], ['G01.358.500.249.820'], ['G01.906']] | ['Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The coalescent in a continuous, finite, linear population. | In this article we present a model for analyzing patterns of genetic diversity in a continuous, finite, linear habitat with restricted gene flow. The distribution of coalescent times and locations is derived for a pair of sequences sampled from arbitrary locations along the habitat. The results for mean time to coalesc... | ['Animals', 'Fishes', 'Genetic Variation', 'Genetics, Population', 'Models, Genetic', 'Monte Carlo Method'] | 12,072,481 | [['B01.050'], ['B01.050.150.900.493'], ['G05.365'], ['H01.158.273.343.335'], ['E05.599.395.397'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Changes in hair properties by Eucalyptus extract. | A long-term usage investigation of a scalp lotion containing Eucalyptus extract, which increases the amount of ceramide in the skin, was carried out to explore the change in physical properties of the hair fiber. Half-head or whole-head usage studies of a scalp lotion with Eucalyptus extract were carried out for the fo... | ['Adult', 'Asian Continental Ancestry Group', 'Elastic Modulus', 'Eucalyptus', 'European Continental Ancestry Group', 'Female', 'Hair', 'Hair Preparations', 'Humans', 'Male', 'Microscopy, Atomic Force', 'Plant Extracts', 'Protein Structure, Secondary', 'Spectrophotometry, Infrared', 'Young Adult'] | 19,156,331 | [['M01.060.116'], ['M01.686.508.200'], ['G01.374.590.605'], ['B01.650.940.800.575.912.250.773.366'], ['M01.686.508.400'], ['A17.360'], ['D27.720.269.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['D20.215.784.500', 'D26.667'], ['G02.111.570.820.709.600'], ['E05.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pre-eclampsia in a second pregnancy. | The incidence of pre-eclampsia in a second pregnancy has been studied in 6,637 women for Aberdeen City whose pregnancies occurred between 1969 and 1978. The rate of pre-eclampsia in second pregnancy is less than in first pregnancy, but this is altered by the outcome of the first pregnancy with reference to length of ge... | ['Abortion, Induced', 'Abortion, Spontaneous', 'Female', 'Gestational Age', 'Humans', 'Parity', 'Pre-Eclampsia', 'Pregnancy', 'Proteinuria', 'Scotland'] | 6,872,288 | [['E04.520.050'], ['C13.703.039', 'G08.686.784.769.496.125'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'], ['C13.703.395.249'], ['G08.686.784.769'], ['C12.777.934.734', 'C13.351.968.934.734', 'C23.888.942.750'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Fructose-2,6-bisphosphate counteracts guanidinium chloride-, thermal-, and ATP-induced dissociation of skeletal muscle key glycolytic enzyme 6-phosphofructo-1-kinase: A structural mechanism for PFK allosteric regulation. | Rabbit muscle 6-phosphofructo-1-kinase (PFK) is the key glycolytic enzyme being regulated by diverse molecules and signals. This enzyme may undergo a reversible dissociation from a fully active homotetramer to a quite inactive dimer. There are evidences that some positive and negative modulators of PFK, such as ADP and... | ['Adenosine Triphosphate', 'Animals', 'Computer Simulation', 'Enzyme Activation', 'Fructosediphosphates', 'Glycolysis', 'Guanidine', 'Isomerism', 'Models, Chemical', 'Muscle, Skeletal', 'Phosphofructokinase-1', 'Phosphoprotein Phosphatases', 'Rabbits', 'Structure-Activity Relationship', 'Temperature'] | 17,923,106 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['L01.224.160'], ['G02.111.263', 'G03.328'], ['D09.894.417.313.300', 'D09.894.417.592.300'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['D02.078.370.472'], ['G02.111.570.685', 'G02.607.445'], ['E05.599.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Purification of cytotoxic enterotoxin of Aeromonas sobria by use of monoclonal antibodies. | Cytotoxic enterotoxin of Aeromonas sobria was purified by affinity chromatography with monoclonal antibodies. The purified enterotoxin gave a single protein band in polyacrylamide gradient gel electrophoresis and its mol. wt estimated by this technique was 63,000; it had a pI of 6.2. The purified enterotoxin caused flu... | ['Aeromonas', 'Animals', 'Antibodies, Monoclonal', 'Bacterial Toxins', 'Cell Line', 'Cholera Toxin', 'Cytotoxins', 'Enterotoxins', 'Hemolysin Proteins', 'Immunodiffusion', 'Molecular Weight'] | 3,104,592 | [['B03.440.450.019.025'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.946.123'], ['A11.251.210'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['D27.888.569.213'], ['D23.946.330'], ['D12.776.543.695.444'], ['E01.370.225.812.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transgenic mouse á- and â-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences. | Familial hypertrophic cardiomyopathy (FHC) is a major cause of sudden cardiac death in young athletes. The discovery in 1990 that a point mutation at residue 403 (R403Q) in the â-myosin heavy chain (MHC) caused a severe form of FHC was the first of many demonstrations linking FHC to mutations in muscle proteins. A mous... | ['Adenosine Diphosphate', 'Amino Acid Substitution', 'Animals', 'Kinetics', 'Mice', 'Mice, Transgenic', 'Mutation, Missense', 'Myosin Heavy Chains', 'Protein Binding', 'Ventricular Myosins'] | 23,580,644 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['G05.365.590.650'], ['D05.750.078.730... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of ozone against endodontopathogenic microorganisms in a root canal biofilm model. | AIM: To assess the antimicrobial efficacy of aqueous (1.25-20 microg mL(-1)) and gaseous ozone (1-53 g m(-3)) as an alternative antiseptic against endodontic pathogens in suspension and a biofilm model.METHODOLOGY: Enterococcus faecalis, Candida albicans, Peptostreptococcus micros and Pseudomonas aeruginosa were grown ... | ['Anti-Infective Agents, Local', 'Biofilms', 'Buffers', 'Candida albicans', 'Chlorhexidine', 'Colony Count, Microbial', 'Dental Pulp Cavity', 'Dose-Response Relationship, Drug', 'Enterococcus faecalis', 'Gases', 'Humans', 'Hydrogen Peroxide', 'Oxidants', 'Oxidants, Photochemical', 'Ozone', 'Peptostreptococcus', 'Pseudo... | 19,125,975 | [['D27.505.954.122.187'], ['A20.593', 'G06.120'], ['D27.720.470.280'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D02.078.370.141.100'], ['E01.370.225.875.220', 'E05.200.875.220'], ['A14.549.167.900.265'], ['G07.690.773.875', 'G07.690.936.500'], ['B03.353.750.250.250.280', 'B03.510.550... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Improved operational stability of chloroperoxidase through use of antioxidants. | Chloroperoxidase (CPO) from Caldariomyces fumago is a potentially very useful enzyme due to its ability to catalyze a large variety of stereoselective oxidation reactions, but poor operational stability is a main limitation for commercial use. In the present study, the possibility of increasing the operational stabilit... | ['Antioxidants', 'Caffeic Acids', 'Catalysis', 'Chloride Peroxidase', 'Chromatography, High Pressure Liquid', 'Enzyme Stability', 'Fungal Proteins', 'Hydrogen Peroxide', 'Kinetics', 'Mitosporic Fungi', 'Molecular Structure', 'Oxidants', 'tert-Butylhydroperoxide'] | 18,479,771 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.241.223.200.054'], ['G02.130'], ['D08.811.682.732.360'], ['E05.196.181.400.300'], ['E05.916.360', 'G02.111.700.500'], ['D12.776.354'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G01.374.661', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photoaffinity labeling of the nucleotide-binding site of the uncoupling protein from hamster brown adipose tissue. | The nucleotide binding center of the uncoupling protein from brown adipose tissue (UCP) was probed by photoaffinity labeling with 8-azido-ATP. The isolated dimeric UCP in non-ionic detergent was used. 8-azido-ATP binds to UCP with a Kd = 3 microM, i.e. with an only threefold lower affinity than ATP and a maximum number... | ['Adenosine Triphosphate', 'Adipose Tissue, Brown', 'Affinity Labels', 'Amino Acid Sequence', 'Animals', 'Autoradiography', 'Azides', 'Binding Sites', 'Carrier Proteins', 'Cricetinae', 'Cyanogen Bromide', 'Electrophoresis, Polyacrylamide Gel', 'Ion Channels', 'Membrane Proteins', 'Mitochondrial Proteins', 'Molecular Se... | 1,730,236 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A10.165.114.322'], ['D27.720.470.410.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D01.625.100', 'D02.159'], ['G02.111.570.120'], ['D12.776.157'], ['B01.050.15... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate. | Previously, it was shown that the D enantiomer of isoidide dinitrate was 10-fold more potent than the L enantiomer and 10-fold less potent than glyceryl trinitrate for stimulating cyclic GMP accumulation and relaxation of isolated rat aorta. In the present study, these organic nitrates were tested for their ability to ... | ['Animals', 'Aorta', 'Cyclic GMP', 'Dose-Response Relationship, Drug', 'Drug Tolerance', 'Guanylate Cyclase', 'Male', 'Muscle, Smooth, Vascular', 'Nitrates', 'Nitroglycerin', 'Rats', 'Rats, Inbred Strains', 'Stereoisomerism', 'Sugar Alcohols', 'Vasodilation'] | 2,901,920 | [['B01.050'], ['A07.015.114.056'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.992'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['D0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neonatal polycythemia: I. Criteria for diagnosis and treatment. | In order to better define criteria for diagnosis and treatment of neonatal polycythemia, 74 neonates with peripheral venous hematocrit levels greater than or equal to 65% were studied. The hematocrit levels of capillary (Cap Hct), peripheral venous (PV Hct), and umbilical venous (UV Hct) blood was measured. Viscosity o... | ['Exchange Transfusion, Whole Blood', 'Female', 'Fetal Blood', 'Hematocrit', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Polycythemia'] | 7,267,222 | [['E02.095.135.469'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['C15.378.738']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incidence of unanticipated uterine pathology at the time of minimally invasive abdominal sacrocolpopexy. | STUDY OBJECTIVE: To determine the incidence of unanticipated uterine pathologic findings in women undergoing hysterectomy concomitant with minimally invasive sacrocolpopexy.DESIGN: Retrospective case series (Canadian Task Force classification III).SETTING: Four institutions in the United States.PATIENTS: Women undergoi... | ['Aged', 'Female', 'Humans', 'Hysterectomy', 'Incidence', 'Incidental Findings', 'Middle Aged', 'Pelvic Organ Prolapse', 'Retrospective Studies', 'Uterine Diseases'] | 23,911,564 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E01.410'], ['M01.060.116.630'], ['C23.300.842.624'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Should surgeons still be implanting pacemakers? | Cardiac pacing has undergone major changes in the areas of manpower, technology, and cost over the past 10 years. Arguments have been made to eliminate cardiac surgical involvement in pacing on the basis of these three areas of change: implantations are increasingly performed by nonsurgeons, surgeons have not kept up w... | ['Cardiac Pacing, Artificial', 'Cardiac Surgical Procedures', 'Humans', 'Pacemaker, Artificial', "Physician's Role", 'Postoperative Complications', 'Prostheses and Implants'] | 8,147,626 | [['E02.331.200'], ['E04.100.376', 'E04.928.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.750'], ['F01.829.316.616.625.600'], ['C23.550.767'], ['E07.695']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of natural and recombinant cholera toxin B subunit as stimulatory factors in intranasal immunization. | Cholera toxin B (CTB) is often envisaged and used as an immune stimulating agent in protocols for mucosal immunization. However, the nature of the CTB used (natural vs recombinant) is frequently not taken in consideration. This is important since the usage of natural CTB in mucosal immunization regimen and the mucosal ... | ['Adjuvants, Immunologic', 'Administration, Intranasal', 'Animals', 'Antibody Formation', 'Antigens', 'Cholera Toxin', 'Immunity, Mucosal', 'Immunization', 'Immunoglobulin A', 'Immunoglobulin G', 'Mice', 'Mice, Inbred C3H', 'Ovalbumin', 'Recombinant Proteins'] | 9,269,054 | [['D27.505.696.477.067'], ['E02.319.267.120.655.500'], ['B01.050'], ['G12.450.050.370.250'], ['D23.050'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['G12.450.573'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['D12.776.124.486... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Channel selection for optimizing feature extraction in an electrocorticogram-based brain-computer interface. | Feature extractor and classifier are two major components in a brain-computer interface system, in which the feature extractor plays a critical role. To increase the discriminability of features or feature vectors used for classification, it is necessary to select a suitable number of task-related data recording channe... | ['Algorithms', 'Artificial Intelligence', 'Cerebral Cortex', 'Discriminant Analysis', 'Electroencephalography', 'Epilepsies, Partial', 'Humans', 'Pattern Recognition, Automated', 'User-Computer Interface'] | 20,844,441 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['A08.186.211.200.885.287.500'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.399.750'], ['L01.224.900.910']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Asymptomatic Helicobacter pylori infection and iron deficiency are not associated with decreased growth among Alaska Native children aged 7-11 years. | INTRODUCTION: Alaska Native children have high Helicobacter pylori infection and iron deficiency prevalences, and their average height-for-age is lower than US reference populations. During a clinical trial to determine the impact of H. pylori treatment on iron deficiency, we evaluated the effects of H. pylori infectio... | ['Alaska', 'Anemia, Iron-Deficiency', 'Anti-Bacterial Agents', 'Body Height', 'Body Mass Index', 'Body Weight', 'Child', 'Ferritins', 'Growth Disorders', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Inuits', 'Iron Metabolism Disorders', 'Rural Population', 'Treatment Outcome'] | 16,684,263 | [['Z01.107.567.875.580.100'], ['C15.378.071.196.300', 'C18.452.565.100'], ['D27.505.954.122.085'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.... | ['Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Husbandry, health and biosecurity of the smallholder and pet pig population in England. | Three hundred and thirteen pet and smallholder pig owners in England responded to an online questionnaire regarding husbandry and healthcare of their pigs. There was a lack of knowledge of the legislation regarding Department for Environment, Food and Rural Affairs (DEFRA) registration, animal movements and feeding of ... | ['Animal Husbandry', 'Animal Welfare', 'Animals', 'Communicable Diseases', 'England', 'Feeding Methods', 'Government Agencies', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Legislation, Veterinary', 'Pets', 'Registries', 'Risk Assessment', 'Security Measures', 'Surveys and Questionnaires', 'Swine', 'Travel', 'Va... | 26,116,269 | [['J01.040.090'], ['I01.880.604.100'], ['B01.050'], ['C01.221', 'C23.550.291.531'], ['Z01.542.363.300'], ['E02.421'], ['I01.409.418', 'N03.540.400'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.615.686'], ['B01.050.050.116.600'], ['E05.318.308.970', 'N04.452.859.81... | ['Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
A new method for the direct estimation of blood oxygen content. | Identical blood samples were estimated for oxygen content by a fuel cell analyser (the "Lex-O2-Con'), and by the Van Slyke manometric technique. The new instrument was found to be accurate and repeatable, as well as quicker and easier to operate. Its response to oxygen was found to be unaffected by the presence of comm... | ['Blood Gas Analysis', 'Halothane', 'Humans', 'Manometry', 'Nitrous Oxide', 'Oxygen'] | 1,175,189 | [['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['D02.455.526.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['D01.362.635.625', 'D01.625.550.550', 'D01.650.550.587.650'], ['D01.268.185.550', 'D01.362.670']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photoaffinity labeling of steroid binding proteins with unmodified ligands. | Photoactivation of the alpha,beta-unsaturated ketones of natural and synthetic steroid molecules by light of lambda greater than or equal to 330 nm allows their covalent attachment to steroid-binding proteins. The general validity of this method is demonstrated with two steroid hormone receptors and the steroid-binding... | ['Affinity Labels', 'Glycoproteins', 'Ligands', 'Light', 'Peptides', 'Photochemistry', 'Receptors, Progesterone', 'Receptors, Steroid', 'Uteroglobin'] | 7,341,237 | [['D27.720.470.410.080'], ['D09.400.430', 'D12.776.395'], ['D27.720.470.480'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D12.644'], ['H01.181.529.711'], ['D12.776.826.750.765'], ['D12.776.826.750', 'D12.776.930.778'], ['D12.776.861.500']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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