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[Potential of Bacillus thuringiensis israelensis Berliner for controlling Aedes aegypti]. | The importance of the entomopathogenic bacterium Bacillus thuringiensis israelensis in the control of Aedes aegypti is presented. The use and potential of B. thuringiensis israelensis against the mosquito vector of dengue fever is described. Other aspects such as insect's resistance development against chemicals and ad... | ['Aedes', 'Animals', 'Bacillus thuringiensis', 'Brazil', 'Child', 'Child, Preschool', 'Dengue', 'Humans', 'Infant', 'Infant, Newborn', 'Insect Vectors', 'Mosquito Control'] | 14,666,315 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['C01.920.500.270', 'C01.925.081.270', 'C... | ['Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
From mice to humans: identification of commonly deregulated genes in mammary cancer via comparative SAGE studies. | Genetically engineered mouse mammary cancer models have been used over the years as systems to study human breast cancer. However, much controversy exists on the utility of such models as valid equivalents to the human cancer condition. To perform an interspecies gene expression comparative study in breast cancer we us... | ['Animals', 'Apoptosis', 'Breast Neoplasms', 'Cell Division', 'Chemokine CCL2', 'Chemokine CXCL1', 'Chemokines, CXC', 'Cytokines', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Interleukin-6', 'Leukemia Inhibitory Factor', 'M... | 15,520,179 | [['B01.050'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D12.644.276.374.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An investigation of enumeration and DNA partitioning in Bacillus subtilis L-form bacteria. | Cell numbers of two morphogenic forms of Bacillus subtilis (the cell-walled parental and the derived stable cell wall-deficient L-form) have been compared by two methods: DNA hybridization (i.e. deduced genome numbers) and viable cell counts (i.e. number of colony-forming units (cfu)). The DNA hybridization method was ... | ['Bacillus subtilis', 'Colony Count, Microbial', 'DNA, Bacterial', 'Genome, Bacterial', 'L Forms', 'Nucleic Acid Hybridization', 'Plasmids', 'Transformation, Genetic'] | 8,002,476 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D13.444.308.212'], ['G05.360.340.358.207'], ['B03.110.422', 'B05.110.422'], ['E05.393.661', 'G02.111.611'], ['G05.360.600'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in myocardial metabolism induced by ethanol administration. | The utilization of ethyl alcohol in the myocardium and the reactions connected with its metabolism were investigated in rabbits which were given over a period of two months a 30% ethanol solution per os in a dosage of 1 g/kg body weight, and in a control group. Alcohol intoxication led to a reduction of the reserve of ... | ['Alcoholism', 'Animals', 'Ethanol', 'Humans', 'Mitochondria, Heart', 'Myocardium', 'Rabbits'] | 6,684,536 | [['C25.775.100.250', 'F03.900.100.350'], ['B01.050'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.564.627.603', 'A11.284.835.626.627.603'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B01.050.150.900.649.313.968.700']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrolytes of breast-cyst fluid. | We constructed an electrolyte balance sheet for 11 individual specimens and two pooled specimens of breast-cyst fluid. Na+ and K+ ranged in concentrations from those representative of extracellular fluids (147 and 9 mmol/L, respectively) to those of intracellular fluid or a high K+ secretion (23 and 168 mmol/L, respect... | ['Bicarbonates', 'Breast Diseases', 'Calcium', 'Chlorides', 'Cysts', 'Electrolytes', 'Female', 'Humans', 'Osmolar Concentration', 'Potassium', 'Sodium'] | 436,244 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence. | The human gut microbiota is impacted by host nutrition and health status and therefore represents a potentially adaptive phenotype influenced by metabolic and immune constraints. Previous studies contrasting rural populations in developing countries to urban industrialized ones have shown that industrialization is stro... | ['African Continental Ancestry Group', 'Animals', 'Diet', 'Entamoeba', 'Feces', 'Fishes', 'Gastrointestinal Microbiome', 'Genetic Variation', 'Humans', 'Phenotype', 'Rural Population', 'Tanzania'] | 26,619,199 | [['M01.686.508.100'], ['B01.050'], ['G07.203.650.240'], ['B01.046.500.100.700.335'], ['A12.459'], ['B01.050.150.900.493'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.695'], ['N01.600.725'], ['Z01.058.290.120.840'... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice. | Accumulating data links inflammation, oxidative stress and immune system in the pathophysiology of major depressive disorders. Sickness behaviour is a set of behavioural changes that develop during infection, eventually leading to decrease in mobility and depressed behaviour. Lipopolysaccharide (LPS) induces a depressi... | ['Animals', 'Anti-Inflammatory Agents', 'Antioxidants', 'Behavior, Animal', 'Brain', 'Caffeic Acids', 'Cytokines', 'Illness Behavior', 'Inflammation', 'Lipopolysaccharides', 'Male', 'Mice', 'Oxidative Stress'] | 27,597,761 | [['B01.050'], ['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['F01.145.113'], ['A08.186.211'], ['D02.241.223.200.054'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['F01.145.499'], ['C23.550.470'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Male clients of female commercial sex workers: HIV, STDs and risk behaviour. | Social stigma and taboo limit current understanding of sexual behaviours and epidemiology of sexually transmitted infections (STIs) in clients of commercial sex workers/prostitutes. We designed a study to determine risk behaviours and prevalence of STIs in a group of sexual health clinic attending male clients of femal... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Australia', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Risk-Taking', 'Sex Work', 'Sexual Behavior', 'Sexually Transmitted Diseases'] | 11,564,334 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['F01.145.722'], ['... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Native Italian speakers' perception and production of English vowels. | This study examined the production and perception of English vowels by highly experienced native Italian speakers of English. The subjects were selected on the basis of the age at which they arrived in Canada and began to learn English, and how much they continued to use Italian. Vowel production accuracy was assessed ... | ['Adolescent', 'Adult', 'Child', 'Humans', 'Language', 'Middle Aged', 'Phonetics', 'Speech', 'Speech Perception', 'Speech Production Measurement'] | 10,573,909 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['M01.060.116.630'], ['L01.559.598.518'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['F02.463.593.071.875', 'G07.888.125.875'], ['E01.370.760']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Strain-specificity of antibody to haemagglutinin following inactivated A/port chalmers/1/73 vaccine in man: evidence for a paradoxical strain-specific antibody response. | An analysis was carried out of the anti-haemagglutinin antibody responses in adult human recipients of inactivated whole virus A/Port Chalmers/1/73 (H3N2) vaccine using single radial diffusion combined with antibody adsorption techniques to determine antibody specificity. Antibody was characterised as cross-reactive (i... | ['Antibodies, Viral', 'Cross Reactions', 'Hemagglutinins, Viral', 'Humans', 'Immunization', 'Influenza A virus', 'Influenza Vaccines', 'Species Specificity', 'Time Factors'] | 604,109 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G12.122.281'], ['D12.776.964.970.880.345', 'D23.050.327.461'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Depletion of gentamicin and its major components from various tissues of turkeys. | OBJECTIVE: To determine tissue depletion profiles for gentamicin and its 3 major components (C1, C1a, and C2) in turkeys.ANIMALS: Twenty 10-week-old male turkeys.PROCEDURE: birds were maintained as untreated controls. The remaining birds were treated with gentamicin sulfate at a dosage of 2 mg/kg, IM, once daily for 5 ... | ['Adipose Tissue', 'Animals', 'Anti-Bacterial Agents', 'Gentamicins', 'Kidney', 'Kinetics', 'Liver', 'Male', 'Metabolic Clearance Rate', 'Muscle, Skeletal', 'Skin', 'Tissue Distribution', 'Turkeys'] | 14,596,459 | [['A10.165.114'], ['B01.050'], ['D27.505.954.122.085'], ['D09.408.051.374'], ['A05.810.453'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['A02.633.567', 'A10.690.552.500'], ['A17.815'], ['G03.787.917', 'G07.690.725.949'], ['B01.050.150.9... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response. | Antiretroviral neutralizing antibody (NAb) responses are often evaluated in the absence of Fc-dependent immune effectors. In murine Friend retrovirus infection, Apobec3/Rfv3 promotes a potent polyclonal NAb response. Here, we show that the Apobec3/Rfv3-dependent NAb response correlated with virus-specific IgG2 titers a... | ['Animals', 'Antibodies, Neutralizing', 'Antibodies, Viral', 'Cytidine Deaminase', 'Friend murine leukemia virus', 'Immunoglobulin Fc Fragments', 'Immunoglobulin G', 'Mice, Inbred C57BL'] | 25,589,647 | [['B01.050'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D08.811.277.151.486.250'], ['B04.613.807.375.525.225', 'B04.820.650.375.525.225'], ['D12.644.541.500.697', 'D12.77... | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activation. | OBJECTIVE: Platelets play a dual role in thrombosis by forming aggregates and stimulating coagulation. We investigated the commitment of platelets to these separate functions during collagen-induced thrombus formation in vitro and in vivo.METHODS AND RESULTS: High-resolution 2-photon fluorescence microscopy revealed th... | ['Animals', 'Blood Coagulation', 'Blood Platelets', 'Hemorheology', 'Humans', 'Mice', 'Microscopy, Fluorescence', 'Platelet Aggregation', 'Platelet Glycoprotein GPIIb-IIIa Complex', 'Thrombosis'] | 17,761,939 | [['B01.050'], ['G09.188.390.150'], ['A11.118.188', 'A15.145.229.188'], ['E05.830.250', 'G09.188.370', 'G09.330.380.630'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.458', 'E05.595.458'], ['G09.188.370.687', 'G09.188.390.600.640'], ['D12.776.395.550.62... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The broad distribution of GP2 in mucous glands and secretory products. | GP2, a GPI-anchored glycoprotein that is a useful marker for M cells of Peyer's patches, is functionally related to the uptake of pathogenic bacteria in the gut lumen. Our immunostaining throughout the whole body of mice detected a broader localization than previously found of GP2 in various mucous glands and secretory... | ['Animals', 'Exocrine Glands', 'Female', 'GPI-Linked Proteins', 'Gastrointestinal Microbiome', 'Gene Expression', 'Immunohistochemistry', 'Intracellular Space', 'Mice', 'Mucus', 'Protein Transport'] | 28,003,582 | [['B01.050'], ['A10.336'], ['D12.776.395.550.448', 'D12.776.543.484.500', 'D12.776.543.550.418'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['G05.297'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Autogenous translational regulation of the Borna disease virus negative control factor X from polycistronic mRNA using host RNA helicases. | Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that employs several unique strategies for gene expression. The shortest transcript of BDV, X/P mRNA, encodes at least three open reading frames (ORFs): upstream ORF (uORF), X, and P in the 5' to 3' direction. The X is a negative regulator of viral ... | ['Borna disease virus', 'Gene Expression Regulation, Viral', 'Host-Pathogen Interactions', 'RNA Helicases', 'RNA, Viral', 'Viral Regulatory and Accessory Proteins'] | 19,893,625 | [['B04.820.480.937.149.135'], ['G05.308.385'], ['G06.462', 'G16.527.200'], ['D08.811.913.696.445.735.720'], ['D13.444.735.828'], ['D12.776.964.925']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sex differences in renin-angiotensin-aldosterone system affect extracellular volume in healthy subjects. | Several studies reported sex differences in aldosterone. It is unknown whether these differences are associated with differences in volume regulation. Therefore we studied both aldosterone and extracellular volume in men and women on different sodium intakes. In healthy normotensive men ( n = 18) and premenopausal wome... | ['Adrenal Glands', 'Adult', 'Aldosterone', 'Angiotensin II', 'Blood Pressure', 'Body Water', 'Cross-Over Studies', 'Diet, Sodium-Restricted', 'Female', 'Fluid Shifts', 'Healthy Volunteers', 'Humans', 'Infusions, Intravenous', 'Male', 'Random Allocation', 'Renin-Angiotensin System', 'Sex Factors', 'Sodium, Dietary', 'Wa... | 28,592,435 | [['A06.300.071'], ['M01.060.116'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A12.207.200'], ['E05.318.370.150', ... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparative study of serum ultrafiltrable, ionized, and total calcium in the diagnosis of primary hyperparathyroidism in patients with intermittent or no elevation in total calcium. | Measurement of serum ionized calcium has been shown to be more sensitive a method of diagnosing primary hyperparathyroidism than total calcium in patients with subtle or intermittent elevations of total calcium. The measurement of ionized calcium, however, is technically difficult. The measurement of serum ultrafiltrab... | ['Calcium', 'Hemofiltration', 'Humans', 'Hyperparathyroidism', 'Ions', 'Regression Analysis'] | 3,194,840 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E02.870.225', 'E04.292.471'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355'], ['D01.248.497'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Glycomics for drug discovery: metabolic perturbation in androgen-independent prostate cancer cells induced by unnatural hexosamine mimics. | Inhibited: N-acetylglucosamine (GlcNAc) derivatives with a fluorine atom at the C4 position (2-4) were synthesized, and their ability to inhibit cancer-cell growth was investigated. The administration of these 4F-GlcNAc derivatives to cells led to the unnatural sugar nucleotide 1. Furthermore, N-glycan profiles of cell... | ['Acetylglucosamine', 'Androgens', 'Apoptosis', 'Carbohydrate Sequence', 'Cell Line, Tumor', 'Drug Evaluation, Preclinical', 'Fluorine', 'Glycomics', 'Glycosylation', 'Humans', 'Male', 'Molecular Sequence Data', 'Prostatic Neoplasms'] | 22,345,046 | [['D09.067.342.531.050'], ['D27.505.696.399.472.161'], ['G04.146.954.035'], ['G02.111.570.160', 'L01.453.245.667.160'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.290.750', 'E05.337.550'], ['D01.268.380.300'], ['H01.158.201.085.320', 'H01.158.273.180.350.150', 'H01.158.273.343.350.086', 'H01.181.122.508'], ['G02.111... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Biomechanical and physical properties of lengthened bone in a canine model. | Reports on the mechanical and physical properties of lengthened bone after completion of the lengthening process remain scarce. Varied results of torsional testing of lengthened bone have been reported. Furthermore, torsional testing provides information on the shear properties of the tissue but does not reflect the el... | ['Analysis of Variance', 'Animals', 'Biomechanical Phenomena', 'Bone Density', 'Bone Lengthening', 'Dogs', 'External Fixators', 'Radiography', 'Tensile Strength', 'Tibia', 'Time Factors', 'Torsion Abnormality'] | 8,070,201 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['G11.427.100'], ['E04.555.120'], ['B01.050.150.900.649.313.750.250.216.200'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['E01.370.350.700'], ['G01.374.850'], ['A02.835.232.043.650.883'], ['G01.910.857... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cardiovascular autonomic dysfunction predicts severe hypoglycemia in patients with type 2 diabetes: a 10-year follow-up study. | OBJECTIVE The aim of this study was to investigate the development of severe hypoglycemia (SH) in the presence of cardiovascular autonomic neuropathy (CAN) in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS From January 2001 to December 2002, a total of 894 patients with type 2 diabetes were enrolled. A card... | ['Adult', 'Aged', 'Autonomic Nervous System', 'Cardiovascular System', 'Cohort Studies', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Heart Rate', 'Humans', 'Hypoglycemia', 'Incidence', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Posture', 'Predictive Value of Tests', 'Prospective Studies', 'Regress... | 23,959,567 | [['M01.060.116'], ['M01.060.116.100'], ['A08.800.050'], ['A07'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.875.500', 'G09.330.380.500'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Spirometry results after treatment for pulmonary tuberculosis: comparison between patients with and without previous lung disease: a multicenter study. | OBJECTIVE: To compare patients with and without previous lung disease, in terms of the spirometry results after they had been treated for pulmonary tuberculosis (PTB) and cured, as well as to analyze risk factors related to functional severity.METHODS: This was a cross-sectional, multicenter study conducted at four ref... | ['Antitubercular Agents', 'Brazil', 'Case-Control Studies', 'Cross-Sectional Studies', 'Humans', 'Lung', 'Lung Diseases', 'Respiratory Function Tests', 'Severity of Illness Index', 'Smoking', 'Spirometry', 'Tuberculosis, Pulmonary'] | 32,130,330 | [['D27.505.954.122.085.255'], ['Z01.107.757.176'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C08.381'], ['E01.370.386.700'], ['E05.318.308.9... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Bilingual medical students as interpreters--what are the benefits and risks? | AIMS: To identify the frequency of medical students interpreting in healthcare settings and to explore the issues related to the use of non-professional interpreters.METHODS: All 4th and 5th year University of Otago medical students were surveyed to identify bilingual medical students who have interpreted for patients.... | ['Communication Barriers', 'Humans', 'Multilingualism', 'Physician-Patient Relations', 'Quality of Health Care', 'Risk Assessment', 'Students, Medical', 'Translating'] | 18,815,600 | [['L01.143.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.423.452'], ['F01.829.401.650.675', 'N05.300.660.625'], ['N04.761', 'N05.715'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['M01.848.769.602'], ['L01.559.423.... | ['Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Drug diffusion mechanism through pH-sensitive hydrophobic/polyelectrolyte hydrogel membranes. | Methylmethacrylate/dimethylaminoethyl methacrylate cross-linked with divinylbenzene is a pH-sensitive hydrogel. We have studied the diffusion mechanisms of drugs with different water solubilities through this hydrogel. A water-soluble model drug (aminopyrine) was used to study the diffusion coefficient changes in diffe... | ['Aminopyrine', 'Caffeine', 'Chemistry, Pharmaceutical', 'Diffusion', 'Hydrogen-Ion Concentration', 'Methylgalactosides', 'Methylmethacrylate', 'Solubility', 'Theobromine'] | 11,343,888 | [['D03.383.129.539.850.077'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['H01.158.703.007', 'H01.181.466'], ['G01.202', 'G02.196'], ['G02.300'], ['D09.408.320.500', 'D09.408.514.455'], ['D02.241.081.069.800.550.450', 'D05.750.716.822.111.650.605.450', 'D25.720.716.822.111.650.605.450', 'J01.637.051.720.716.82... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
A dose-ranging study of ranitidine and its effect on intragastric and intra-oesophageal acidity in subjects with gastro-oesophageal reflux disease. | METHODS: This randomized, double-blind, single-centre, crossover study was designed to assess the effects of three regimens of ranitidine (150 mg b.d., 300 mg b.d. and 300 mg q.d.s.) and placebo on intra-oesophageal and intragastric pH in subjects with gastro-oesophageal reflux disease (GERD). Twenty-six subjects were ... | ['Adult', 'Cross-Over Studies', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Drug Administration Schedule', 'Esophagus', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Middle Aged', 'Posture', 'Ranitidine', 'Stomach'] | 7,986,969 | [['M01.060.116'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['A03.556.875.500'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Capillary electrophoretic determination of S-carboxymethyl-L-cysteine and its major metabolites in human urine: feasibility investigation using on-column detection of non-derivatized solutes in capillaries with minimal electroosmosis. | The capillary electrophoretic analysis of S-carboxymethyl-L-cysteine and some of its metabolites in human urine is reported using (i) on-column detection of underivatized solutes, (ii) minimal sample pretreatment and (iii) capillary columns with minimized electroosmosis. Experimental results obtained with two apparatus... | ['Carbocysteine', 'Electrophoresis', 'Humans', 'Molecular Structure', 'Osmosis'] | 2,257,847 | [['D02.886.030.230.310', 'D12.125.119.270', 'D12.125.166.230.310'], ['E05.196.401', 'E05.301.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['G01.154.090.750', 'G02.111.655', 'G02.691', 'G02.723.495']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The clinico-instrumental characteristics of the lesions of the precerebral arteries in patients with atherosclerotic circulatory encephalopathy]. | Results have been analysed of comprehensive evaluation of 175 patients with discirculatory encephalopathy of atherosclerotic genesis, consisting of inspection of the neck vessels projection, study of neurological status, ultrasonic investigation of the major brain arteries structure and hemodynamics, their angiographic... | ['Adult', 'Aged', 'Arteries', 'Brain', 'Cerebrovascular Disorders', 'Diagnosis, Differential', 'Female', 'Humans', 'Intracranial Arteriosclerosis', 'Ischemic Attack, Transient', 'Male', 'Middle Aged', 'Neurologic Examination'] | 7,975,546 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114'], ['A08.186.211'], ['C10.228.140.300', 'C14.907.253'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.800', 'C14.907.137.126.372', 'C14.907.253.560.350'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['M01.060.116.630'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment with TNF-alpha and IFN-gamma alters the activation of SER/THR protein kinases and the metabolic response to IGF-I in mouse c2c12 myogenic cells. | UNLABELLED: The aim of this study was to compare the effects of TNF-alpha, IL-1beta and IFN-gamma on the activation of protein kinase B (PKB), p70(S6k), mitogen-activated protein kinase (MAPK) and p90( rsk ), and on IGF-I-stimulated glucose uptake and protein synthesis in mouse C2C12 myotubes. 100 nmol/l IGF-I stimulat... | ['Animals', 'Cell Line', 'Glucose', 'Insulin-Like Growth Factor I', 'Interferon-gamma', 'Interleukin-1beta', 'Mice', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Muscle Fibers, Skeletal', 'Phosphorylation', 'Protein-Serine-Threonine Kinases', 'Proto-Oncogene Proteins c-akt', 'Ribosomal P... | 19,685,010 | [['B01.050'], ['A11.251.210'], ['D09.947.875.359.448'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['D12.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Daphnane diterpenoids with nitric oxide inhibitory activities and interactions with iNOS from the leaves of Trigonostemon thyrsoideus. | A phytochemical investigation to search for new nitric oxide (NO) inhibitors resulted in the isolation of seven previously undescribed daphnane diterpenoids, thyrsoidpenes A-G, from the leaves of Trigonostemon thyrsoideus. Their structures including absolute configurations were elucidated on the basis of extensive NMR ... | ['Animals', 'Cell Line', 'Diterpenes', 'Euphorbiaceae', 'Lipopolysaccharides', 'Mice', 'Molecular Docking Simulation', 'Nitric Oxide', 'Nitric Oxide Synthase Type II', 'Plant Leaves'] | 29,289,737 | [['B01.050'], ['A11.251.210'], ['D02.455.849.291'], ['B01.650.940.800.575.912.250.859.797.438'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.595.249', 'L01.224.160.249'], ['D01.339.387', 'D01.625.550.500', 'D01.625.7... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Epidermal growth factor receptor gene polymorphisms predict pelvic recurrence in patients with rectal cancer treated with chemoradiation. | An association between epidermal growth factor receptor (EGFR) signaling pathway and response of cancer cells to ionizing radiation has been reported. Recently, a polymorphic variant in the EGFR gene that leads to an arginine-to-lysine substitution in the extracellular domain at codon 497 within subdomain IV of EGFR ha... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Caenorhabditis elegans Proteins', 'Chemotherapy, Adjuvant', 'DNA, Neoplasm', 'ErbB Receptors', 'Female', 'Fluorouracil', 'Humans', 'Male', 'Middle Aged', 'Neoadjuvant Therapy', 'Neoplasm Recurrence, Local', 'Pilot Projects', 'Polymerase Chain Reaction', 'Polymorphism, Genetic... | 15,701,846 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['D12.776.419.500'], ['E02.186.170', 'E02.319.170'], ['D13.444.308.425'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Optimal acquisition schemes in high angular resolution diffusion weighted imaging. | The recent challenge in diffusion imaging is to find acquisition schemes and analysis approaches that can represent non-gaussian diffusion profiles in a clinically feasible measurement time. In this work we investigate the effect of b-value and the number of gradient vector directions on Q-ball imaging and the Diffusio... | ['Algorithms', 'Brain', 'Diffusion Magnetic Resonance Imaging', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Information Storage and Retrieval', 'Nerve Fibers, Myelinated', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 18,982,584 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['E01.370.350.825.500.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.313.500.750.280', 'L01.470'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Closure of a persistent ductus arteriosus of Botallo in two dogs using transarterial coil embolization]. | Non-surgical occlusion of persistent ductus arteriosus (PDA) by catheter guided coil embolisation was performed in two dogs. In both dogs the procedure was performed through the femoral artery. The exact location and the narrowest diameter of the PDA were evaluated angiographically after contrast medium injection into ... | ['Angiography', 'Animals', 'Catheterization, Peripheral', 'Dog Diseases', 'Dogs', 'Ductus Arteriosus, Patent', 'Embolization, Therapeutic', 'Female', 'Femoral Artery', 'Male'] | 10,228,398 | [['E01.370.350.700.060', 'E01.370.370.050'], ['B01.050'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C14.240.400.340', 'C14.280.400.340', 'C16.131.240.400.340'], ['E02.520.360', 'E02.926.500'], ['A07.015.114.351']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Humor: no geriatric nurse should be without it. | Humor is an approach caregivers can use to assist the elderly in facing some of the disappointments of old age. The ability to laugh at oneself, at others, and at situations stimulates trust, commitment, and a positive sense of working together that is therapeutic to both staff and patients. Humor offers a tool for pat... | ['Adaptation, Psychological', 'Aged', 'Communication', 'Geriatric Nursing', 'Humans', 'Nurse-Patient Relations', 'Wit and Humor as Topic'] | 1,327,992 | [['F01.058'], ['M01.060.116.100'], ['F01.145.209', 'L01.143'], ['H02.478.676.236', 'N02.421.533.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650.600', 'N05.300.660.560'], ['F01.100.960', 'K01.517.946']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Mammography facilities serving vulnerable women have longer follow-up times. | OBJECTIVE: To investigate mammography facilities' follow-up times, population vulnerability, system-based processes, and association with cancer stage at diagnosis.DATA SOURCES: Prospectively collected from San Francisco Mammography Registry (SFMR) 2005-2011, California Cancer Registry 2005-2012, SFMR facility survey 2... | ['Breast Neoplasms', 'Delayed Diagnosis', 'Early Detection of Cancer', 'Female', 'Health Status Disparities', 'Humans', 'Mammography', 'Minority Groups', 'Prospective Studies', 'Registries', 'San Francisco', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Time Factors', 'Vulnerable Populations'] | 30,394,526 | [['C04.588.180', 'C17.800.090.500'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['E01.390.500'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['I01.880.853.300'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Team management training using crisis resource management results in perceived benefits by healthcare workers. | BACKGROUND: Systems failures and ineffective teamwork can lead to serious errors in practice. Crisis Resource Management (CRM) teaches leadership, effective communication skills, and improved team performance. The impact of CRM taught in a simulation laboratory was evaluated.METHODS: A mail survey was used to examine p... | ['Attitude of Health Personnel', 'Causality', 'Communication', 'Cooperative Behavior', 'Cross-Sectional Studies', 'Emergencies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Personnel', 'Humans', 'Inservice Training', 'Interprofessional Relations', 'Leadership', 'Male', 'Medical Errors', 'Nursing Educatio... | 17,907,666 | [['F01.100.050', 'N05.300.100'], ['N05.715.350.200', 'N06.850.490.625'], ['F01.145.209', 'L01.143'], ['F01.145.813.115'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['F01.100.150.500', 'N05.300.150.410'], ['M01.526.485', 'N02.360... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
The overwet phenomenon: an optical, micromorphological study of surface moisture in the acid-conditioned, resin-dentin interface. | PURPOSE: To evaluate the morphological effect of different degrees of surface wetness on "wet bonding" upon the acid-conditioned, resin-dentin interface using an acetone-containing adhesive system (All-Bond 2).MATERIALS AND METHODS: Dentin surfaces were conditioned with 10% phosphoric acid (20 seconds), washed and air ... | ['Acid Etching, Dental', 'Composite Resins', 'Dental Bonding', 'Dentin', 'Dentin-Bonding Agents', 'Humans', 'Methacrylates', 'Surface Properties', 'Water'] | 9,002,816 | [['E06.931.475.111'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.095'], ['A14.549.167.900.280'], ['D25.339.291.300', 'J01.637.051.339.291.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.081.069.600'], ['G02.860'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Trust, trolleys and social dilemmas: A replication study. | The present manuscript addresses how perceived trustworthiness of cooperative partners in a social dilemma context is influenced by the moral judgments those partners make on Trolley-type moral dilemmas; an issue recently investigated by Everett, Pizarro, and Crockett (2016). The present research comprises 2 studies th... | ['Cooperative Behavior', 'Game Theory', 'Humans', 'Interpersonal Relations', 'Judgment', 'Morals', 'Trust'] | 28,301,177 | [['F01.145.813.115'], ['G17.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.785.626'], ['F01.829.500', 'K01.752.566'], ['F01.829.401.825']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The study on biomass fraction estimate methodology of municipal solid waste incinerator in Korea. | UNLABELLED: In Korea, the amount of greenhouse gases released due to waste materials was 14,800,000 t CO2eq in 2012, which increased from 5,000,000 t CO2eq in 2010. This included the amount released due to incineration, which has gradually increased since 2010. Incineration was found to be the biggest contributor to gr... | ['Air Pollutants', 'Biomass', 'Environmental Monitoring', 'Gases', 'Incineration', 'Republic of Korea', 'Solid Waste'] | 27,191,178 | [['D27.888.284.101'], ['G16.500.275.157.100', 'N06.230.124.100'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.362'], ['N06.850.860.510.900.600.500'], ['Z01.252.474.557.750'], ['D20.944.730', 'N06.850.460.710.730']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The protective role of symmetric stem cell division on the accumulation of heritable damage. | Stem cell divisions are either asymmetric-in which one daughter cell remains a stem cell and one does not-or symmetric, in which both daughter cells adopt the same fate, either stem or non-stem. Recent studies show that in many tissues operating under homeostatic conditions stem cell division patterns are strongly bias... | ['Animals', 'Cell Division', 'Genes, APC', 'Genomic Instability', 'Intestine, Small', 'Mice', 'Models, Genetic', 'Mutation', 'Stem Cells'] | 25,121,484 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G05.360.340.024.340.375.249.050', 'G05.360.340.024.340.415.400.050'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['A03.556.124.684'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395.397'], ['G05.365.590'], ['A11.872... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A biodynamic understanding of dietborne metal uptake by a freshwater invertebrate. | Aquatic organisms accumulate metals from dissolved and particulate phases. Dietborne metal uptake likely prevails in nature, but the physiological processes governing metal bioaccumulation from diet are not fully understood. We characterize dietborne copper, cadmium, and nickel uptake by a freshwater gastropod (Lymnaea... | ['Animals', 'Fresh Water', 'Invertebrates', 'Metals'] | 18,441,838 | [['B01.050'], ['G16.500.275.280', 'N06.230.232'], ['B01.050.500'], ['D01.552']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Translational Repression Protects Human Keratinocytes from UVB-Induced Apoptosis through a Discordant eIF2 Kinase Stress Response. | This study delineates the mechanisms by which UVB regulates protein synthesis in human keratinocytes and the importance of translational control in cell survival. Translation initiation is regulated by phosphorylation of eukaryotic initiation factor 2 (eIF2-P) that causes decreased global protein synthesis coincident w... | ['Activating Transcription Factor 4', 'Apoptosis', 'Cells, Cultured', 'Humans', 'Immunoblotting', 'Keratinocytes', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Stress, Physiological', 'Transcription Factor CHOP', 'Ultraviolet Rays', 'Unfolded Protein Response', 'eIF-2 Kinase'] | 25,950,825 | [['D12.776.260.108.061.937', 'D12.776.930.127.061.937'], ['G04.146.954.035'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['A11.409.500', 'A11.436.397'], ['D13.444.735.544'], ['E05.393.620.500.706'], ['G07.775'], ['D12.776.260.108.124.875', 'D12.776.660.167.875'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hip arthrography in the assessment of children with developmental dysplasia of the hip and Perthes' disease. | In our unit, children with developmental dysplasia of the hip or Perthes' disease, for whom an operation is considered, undergo examination under anaesthetic and a hip arthrogram. This prospective study assessed whether the arthrogram modified treatment and analysed the reliability of its interpretation. All children u... | ['Anesthesia, General', 'Arthrography', 'Child', 'Child, Preschool', 'Female', 'Hip Dislocation, Congenital', 'Hip Joint', 'Humans', 'Infant', 'Legg-Calve-Perthes Disease', 'Male'] | 18,391,807 | [['E03.155.197'], ['E01.370.350.700.070'], ['M01.060.406'], ['M01.060.406.448'], ['C05.660.297.500', 'C16.131.621.297.500', 'C16.131.621.449'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C05.116.852.175.570']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology. | The American Society for Pharmacology and Experimental Therapeutics has revised the Instructions to Authors for Drug Metabolism and Disposition, Journal of Pharmacology and Experimental Therapeutics, and Molecular Pharmacology These revisions relate to data analysis (including statistical analysis) and reporting but do... | ['Data Analysis', 'Data Interpretation, Statistical', 'Editorial Policies', 'Guidelines as Topic', 'Research Design'] | 31,882,568 | [['H01.548.338'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['L01.737.484'], ['N04.761.700.350', 'N05.700.350'], ['E05.581.500', 'H01.770.644.728']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Estimating the prevalence of mental and somatic disorders in the community: aims and methods of the German National Health Interview and Examination Survey. | This paper outlines the principal aims and design of the German National Health Interview and Examination Survey, mental health supplement (GHS-MHS), the first nationwide, epidemiological study of both somatic and mental health in Germany on a representative sample of 4,181 subjects in the community. Both the broader c... | ['Adolescent', 'Adult', 'Aged', 'Comorbidity', 'Cross-Sectional Studies', 'Data Interpretation, Statistical', 'Disabled Persons', 'Female', 'Germany', 'Health Surveys', 'Humans', 'Interview, Psychological', 'Male', 'Mental Disorders', 'Middle Aged', 'National Health Programs', 'Population Surveillance', 'Prevalence', '... | 12,459,800 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['M01.150'], ['Z01.542.315'], ['E05.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
A model for the shared care of elderly patients with cancer. | A model of care for elderly patients with cancer is suggested that incorporates the concept of shared care by various disciplines but in particular the oncologist and primary care provider or geriatrician. Degrees of participation will vary over time, depending upon the needs of the patient and family. | ['Aged', 'Geriatrics', 'Humans', 'Medical Oncology', 'Models, Organizational', 'Neoplasms', 'Patient Care Team', 'Primary Health Care'] | 20,122,034 | [['M01.060.116.100'], ['H02.403.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['E05.599.670', 'N04.452.534'], ['C04'], ['N04.590.715'], ['N04.590.233.727']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Abnormal magnetic resonance signal in the internal capsule predicts poor neurodevelopmental outcome in infants with hypoxic-ischemic encephalopathy. | OBJECTIVE: The aim of this study was to establish whether abnormal signal intensity in the posterior limb of the internal capsule (PLIC) on magnetic resonance imaging is an accurate predictor of neurodevelopmental outcome at 1 year of age in infants with hypoxic-ischemic encephalopathy (HIE).METHODS: We have examined 7... | ['Basal Ganglia', 'Brain', 'Brain Damage, Chronic', 'Brain Ischemia', 'Cerebral Cortex', 'Developmental Disabilities', 'Dominance, Cerebral', 'Female', 'Follow-Up Studies', 'Humans', 'Hypoxia, Brain', 'Infant', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Neurologic Examination', 'Sensitivity and Specifici... | 9,685,433 | [['A08.186.211.200.885.287.249'], ['A08.186.211'], ['C10.228.140.140'], ['C10.228.140.300.150', 'C14.907.253.092'], ['A08.186.211.200.885.287.500'], ['F03.625.421'], ['F02.830.297', 'G11.561.225'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.4... | ['Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine(H-7), a potent inhibitor of protein kinases, inhibits the differentiation of HL-60 cells induced by phorbol diester. | Treatment of the human promyelocytic leukemia cell line HL-60, with 12-o-tetradecanoylphorbol acetate (TPA) results in the differentiation into macrophage-like cell. A potent inhibitor of protein kinase C, 1-(5-isoquinolinesulfonyl)-2-methylpiperazine(H-7), suppressed the proliferation of HL-60 cells and also inhibited... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'Depression, Chemical', 'Humans', 'Isoquinolines', 'Leukemia, Myeloid, Acute', 'Male', 'Phosphorylation', 'Piperazines', 'Protein Kinase C', 'Sulfonamides', 'Tetradecanoylphorbol Acetate'] | 3,462,446 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['G07.690.773.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.531'], ['C04.557.337.539.275'], ['G02.111.665', 'G02.607.780', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Silibinin suppresses TNF-alpha-induced MMP-9 expression in gastric cancer cells through inhibition of the MAPK pathway. | Tumor necrosis factor (TNF)-alpha is one of the pro-inflammatory cytokines highly expressed in Helicobacter pylori that inhibits gastric acid secretion. In this study we determined the effect of silibinin on TNF-alpha-induced MMP-9 expression in gastric cancer cell lines. MMP-9 mRNA and protein expression was dose-depe... | ['Blotting, Western', 'Cell Line, Tumor', 'Cell Proliferation', 'Flow Cytometry', 'Gene Expression Regulation', 'Humans', 'MAP Kinase Signaling System', 'Matrix Metalloproteinase 9', 'Reverse Transcriptase Polymerase Chain Reaction', 'Silybin', 'Silymarin', 'Stomach Neoplasms', 'Tumor Necrosis Factor-alpha'] | 19,924,065 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The epidemiology of amyotrophic lateral sclerosis in Reggio Emilia, Italy. | Incidence and mortality rates of amyotrophic lateral sclerosis (ALS) vary between countries, and in some studies appear to increase over time. We performed a study to assess ALS incidence in a northern Italy area over a 10-year period. We identified the new cases of probable or definite ALS diagnosed among residents in... | ['Adult', 'Aged', 'Amyotrophic Lateral Sclerosis', 'Death Certificates', 'Female', 'Hospitalization', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Risk Factors'] | 18,615,339 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['E05.318.308.940.350', 'L01.399.250.900.350', 'N04.452.859.264', 'N05.715.360.300.715.315', 'N06.850.520.308.940.350'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Therapeutic strategies for idiopathic chylothorax. | STUDY OBJECTIVES: The objectives of the study were to present our institutional experience of idiopathic chylothorax in children and to propose therapeutic strategies.DESIGN: This was a retrospective, single-center study.PATIENTS: Patients were 6 children (4 boys, 2 girls) presenting with an idiopathic chylothorax diag... | ['Adolescent', 'Child', 'Child, Preschool', 'Chylothorax', 'Combined Modality Therapy', 'Diet, Fat-Restricted', 'Drainage', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Parenteral Nutrition', 'Pleural Effusion', 'Retrospective Studies', 'Risk Assessment', 'Severity of Illness Index', 'Treatment Outcome'] | 18,358,282 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C08.528.142'], ['E02.186'], ['E02.642.249.260', 'G07.203.650.240.260'], ['E02.309', 'E04.237'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.421.505', 'E02.642.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Involvement of unique leucine-zipper motif of PSD-Zip45 (Homer 1c/vesl-1L) in group 1 metabotropic glutamate receptor clustering. | Several scaffold proteins for neurotransmitter receptors have been identified as candidates for receptor targeting. However, the molecular mechanism underlying such receptor clustering and targeting to postsynaptic specializations remains unknown. PSD-Zip45 (also named Homer 1c/vesl-1L) consists of the NH(2) terminus c... | ['Animals', 'Brain', 'COS Cells', 'Carrier Proteins', 'Homer Scaffolding Proteins', 'Leucine Zippers', 'Mice', 'Neuropeptides', 'Rats', 'Rats, Sprague-Dawley', 'Receptor Aggregation', 'Receptors, Kainic Acid', 'Receptors, Metabotropic Glutamate'] | 10,570,153 | [['B01.050'], ['A08.186.211'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D12.776.157'], ['D12.776.476.024.381'], ['G02.111.570.820.709.275.500.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.400', 'D12.776.631.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.70... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attitudes, knowledge, and proficiency in relation to organ donation: a questionnaire-based analysis in donor hospitals in northern Denmark. | The aim of this study was to assess knowledge, attitudes, and proficiency in relation to organ donation among staff members of intensive care units (ICUs) in donor hospitals, and possibly identify areas for improvement. The investigation was carried out as a collaboration between the transplant center and appointed key... | ['Attitude of Health Personnel', 'Attitude to Health', 'Cadaver', 'Denmark', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Medical Staff, Hospital', 'Nursing Staff, Hospital', 'Surveys and Questionnaires', 'Tissue Donors', 'Tissue and Organ Procurement'] | 16,298,563 | [['F01.100.050', 'N05.300.100'], ['F01.100.150', 'N05.300.150'], ['C23.550.260.224'], ['Z01.542.816.124'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.630.490', 'M01.526.485.740.422', 'N02.360.630.490', 'N02.360.740.422'], ['M01.526.485.680.490', 'M01.526.485.7... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Relationships between skin temperature and temporal summation of heat and cold pain. | Temporal summation of heat pain during repetitive stimulation is dependent on C nociceptor activation of central N-methyl-d-aspartate (NMDA) receptor mechanisms. Moderate temporal summation is produced by sequential triangular ramps of stimulation that control skin temperature between heat pulses but do not elicit dist... | ['Adult', 'Cold Temperature', 'Female', 'Hot Temperature', 'Humans', 'Male', 'Middle Aged', 'Pain', 'Pain Measurement', 'Psychophysics', 'Skin Temperature', 'Time Factors'] | 12,843,304 | [['M01.060.116'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pharmacologic study of paclitaxel administered with or without the cytoprotective agent amifostine, and given as a single agent or in combination with epirubicin and cisplatin in patients with advanced solid tumors. | The main purpose of this study was to investigate whether the coadministration of amifostine alters the pharmacokinetic behavior of paclitaxel. Eight patients were included in the study: six received paclitaxel in combination with epirubicin and cisplatin, and two received paclitaxel as a single agent. Doses of paclita... | ['Amifostine', 'Antineoplastic Combined Chemotherapy Protocols', 'Cisplatin', 'Drug Interactions', 'Epirubicin', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Paclitaxel', 'Radiation-Protective Agents', 'Radiation-Sensitizing Agents'] | 11,474,273 | [['D02.705.400.625.050', 'D02.705.539.345.050', 'D02.886.300.692.050'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G07.690.773.968'], ['D02.455.426.559.847.562.050.200.175.200', 'D04.615.562.050.200.175.200', 'D09.408.051.059.200.175.200'], ['B01.050.150.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[3H]WIN 35,428 binding to the dopamine uptake carrier. II. Effect of membrane fractionation procedure and freezing. | In the present study the dopamine transporter on rat striatal membranes was labeled with [3H]WIN 35,428 (2 beta-carbomethoxy-3 beta-(4-fluorophenyl)-tropane) and its binding state or form was compared between fresh and frozen tissue fractionated by various protocols. Freezing striatal tissue resulted in a decrease in b... | ['Animals', 'Carrier Proteins', 'Chemical Fractionation', 'Cocaine', 'Corpus Striatum', 'Dopamine', 'Dopamine Plasma Membrane Transport Proteins', 'Female', 'Freezing', 'Membrane Glycoproteins', 'Membrane Transport Proteins', 'Membranes', 'Nerve Tissue Proteins', 'Osmolar Concentration', 'Rats', 'Rats, Sprague-Dawley',... | 8,189,748 | [['B01.050'], ['D12.776.157'], ['E05.196.155'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D12.776.157.530.450.625.124', 'D12.776.157.530.562.374.500.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of the Mas receptor is upregulated in skeletal muscle wasting. | Skeletal muscle atrophy during sepsis, immobilization, and chronic diseases is characterized by an increase in expression and activity of the muscle-specific ubiquitin 3 ligases atrogin-1 and MuRF-1. The classical renin-angiotensin system (RAS), by high level of circulating angiotensin II (AngII) is directly involved i... | ['Angiotensin II', 'Animals', 'Cells, Cultured', 'Immunoblotting', 'Lipopolysaccharides', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Muscle, Skeletal', 'Muscular Atrophy', 'Polymerase Chain Reaction', 'Protein Binding', 'Receptors, G-Protein-Coupled', 'Up-Regulation'] | 25,208,653 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['A11.251'], ['E05.478.566.320', 'E05.601.470.320'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dental hygiene students' attitudes toward ethical dilemmas in practice. | This article reports the findings of a survey-based study conducted in 2006 to determine graduating dental hygiene students' attitudes toward ethical dilemmas in eight areas of practice: substandard care, overtreatment of patients, scope of practice, fraud, confidentiality, impaired professionals, sexual harassment, ab... | ['Attitude', 'Confidentiality', 'Dental Care', 'Dental Hygienists', 'Disclosure', 'Domestic Violence', 'Ethics, Professional', 'Fraud', 'Health Status', 'Humans', 'Infection Control, Dental', 'Informed Consent', 'Mouth Neoplasms', 'Professional Impairment', 'Professional Practice', 'Risk Factors', 'Sexual Harassment', ... | 19,289,724 | [['F01.100'], ['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['E06.170', 'N02.421.240.190'], ['M01.526.485.067.105.376', 'N02.360.067.105.376'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['I01.198.240.856.350', 'I01.880.735.900.3... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Information Science [L]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Attitudes of hospital staff toward mentally ill patients in a teaching hospital, Turkey. | UNLABELLED: The aim of this study was to examine the attitudes of hospital staff toward major mental diseases: schizophrenia and depression. Negative attitudes were common among all of the hospital staff, and were more common among academicians, resident physicians and nurses. Causes of attitude variations were discuss... | ['Attitude of Health Personnel', 'Attitude to Health', 'Depression', 'Health Services Research', 'Hospitals, Teaching', 'Humans', 'Inpatients', 'Interviews as Topic', 'Personnel, Hospital', 'Schizophrenia', 'Surveys and Questionnaires', 'Turkey', 'Workforce'] | 12,793,512 | [['F01.100.050', 'N05.300.100'], ['F01.100.150', 'N05.300.150'], ['F01.145.126.350'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.30... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Quality control guidelines for testing cefotetan in the reference agar dilution procedure for susceptibility testing of anaerobic bacteria. | Reference values for quality control of in vitro susceptibility tests with cefotetan against anaerobic bacteria were determined in two independent multilaboratory studies with the approved National Committee for Clinical Laboratory Standards agar dilution method and three control strains (Bacteroides fragilis ATCC 2528... | ['Bacteria, Anaerobic', 'Cefotetan', 'Microbial Sensitivity Tests', 'Multicenter Studies as Topic', 'Quality Control', 'Reference Values'] | 2,643,621 | [['B03.130'], ['D02.065.589.099.249.250.199', 'D02.886.665.074.250.199', 'D03.383.129.617.235', 'D03.633.100.300.249.250.199'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E05.318.372.658', 'N05.715.360.330.643', 'N06.850.520.450.643'], ['J01.897.608'], ['E05.978.810']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Early effects of liver regeneration on endocrine pancreas: in vivo change in islet morphology and in vitro assessment of systemic effects on â-cell function and viability in the rat model of two-thirds hepatectomy. | Liver and pancreas share key roles in glucose homeostasis. Liver regeneration is associated with systemic modifications and depends especially on pancreatic hormones. The aim of the study was to investigate the role of systemic factors released after two-thirds hepatectomy (2/3H) on early possible consequences of liver... | ['Animals', 'Cell Proliferation', 'Cell Survival', 'Cell-Derived Microparticles', 'Culture Media, Conditioned', 'Hepatectomy', 'Hepatocyte Growth Factor', 'Insulin', 'Insulin Secretion', 'Insulin-Secreting Cells', 'Liver Regeneration', 'Male', 'Models, Animal', 'Organ Size', 'Rats, Inbred Lew', 'Vascular Endothelial Gr... | 25,376,550 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.284.295.588.500'], ['D27.720.470.305.250', 'E07.206.250'], ['E04.210.556'], ['D12.644.276.374.420', 'D12.776.467.374.420', 'D23.529.374.420'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414.13... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Do differences exist between chronic hepatitis C genotypes 2 and 3? | INTRODUCTION: Six genotypes of the hepatitis C virus (HCV) have been identified thus far, and their distribution is well defined. Genotype 1, which is the most prevalent worldwide, is always compared to genotypes 2 and 3, particularly in terms of treatment response. However, little is known about the differences betwee... | ['Disease Progression', 'Female', 'Genotype', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'RNA, Viral', 'Real-Time Polymerase Chain Reaction', 'Retrospective Studies'] | 24,861,286 | [['C23.550.291.656'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['D13.444.735.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
25-Hydroxy vitamin D3 modulates dendritic cell phenotype and function in Crohn's disease. | BACKGROUND: In Crohn's disease (CrD), vitamin D may help to balance an exaggerated immune response and thereby improve the disease course. The immunomodulating effects depend on the activation of 25-hydroxy vitamin D3 (25-D3), into 1,25-dihydroxy vitamin D3 (1,25-D3). This activation has previously been shown to take p... | ['Adult', 'Antigens, CD', 'Cholecalciferol', 'Crohn Disease', 'Dendritic Cells', 'Female', 'HLA-DR Antigens', 'Humans', 'Immunomodulation', 'Interleukin-6', 'Leukocytes', 'Lipopolysaccharides', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Monocytes', 'Phenotype', 'Tumor Necrosis Factor-alpha', 'Young Adult'] | 23,341,164 | [['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D12.776.395.550.509.400.440', 'D12.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Skull base chordomas: management and results. | Growth patterns of skull base chordomas are related to important neurovascular structures. Local invasiveness results in "clinically malignant" behavior. A high rate of transient neurological deficits occurs following radical surgery. At our institution, the principle of radical removal is not followed at any price. Th... | ['Adult', 'Aged', 'Chordoma', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Skull Base Neoplasms', 'Treatment Outcome'] | 16,565,581 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.465.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['C04.588.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantification of dental plaque through planimetric analysis. | The aim of this study was to develop a planimetric, automatic method for evaluation of the extension and volume of plaque. Series of color macrophotographs of stained plaque were analyzed with a digitizer entering Cartesian coordinate data from the graphic records in a calculator. Estimations were carried out on the re... | ['Adhesiveness', 'Adult', 'Dental Plaque', 'Diagnosis, Oral', 'Evaluation Studies as Topic', 'Humans', 'Photography'] | 265,083 | [['G02.860.139'], ['M01.060.116'], ['C07.793.208.377'], ['E06.342'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600', 'E05.712']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Association between Porphyromonas gingivalis and scaling and root planning therapy]. | OBJECTIVE: Porphyromonas gingivalis (P. gingivalis) is considered to be major putative periodontal pathogens. The purpose of the study was to evaluate P. gingivalis and clinical effects of scaling and root planning (SRP) in 20 subjects after 3 months.METHODS: Twenty periodontitis patients were selected. The mean age wa... | ['Adult', 'Dental Plaque', 'Dental Plaque Index', 'Dental Scaling', 'Female', 'Humans', 'Male', 'Middle Aged', 'Periodontal Attachment Loss', 'Periodontal Pocket', 'Periodontitis', 'Porphyromonas gingivalis', 'Root Planing'] | 18,605,451 | [['M01.060.116'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['E06.721.189.350', 'E06.761.227.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.714.354.750'], ['C07.465... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Renal Disorders and Drug Therapy]. | In recent years, among patients treated with anticancer chemotherapy, the rate of chronic kidney disease has been increasing. Nephropathy is a major potential adverse event in cancer drug therapy. Anticancer chemotherapy, particularly in patients with comorbid chronic kidney disease, requires sufficient examination of ... | ['Antineoplastic Agents', 'Glomerular Filtration Rate', 'Humans', 'Kidney Diseases', 'Neoplasms'] | 28,292,989 | [['D27.505.954.248'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['C04']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chrysotile asbestos and health in Zimbabwe: I. Analysis of miners and millers compensated for asbestos-related diseases since independence (1980). | Data on the health effects caused by locally mined chrysotile asbestos in Zimbabwe have been very limited. The prevailing local view has been that risk is minimal. In this report we critically reassess the cases of 51 individuals with asbestos exposure who have been compensated by the Central Pneumoconiosis Bureau sinc... | ['Asbestos', 'Asbestos, Serpentine', 'Asbestosis', 'Humans', 'Male', 'Mining', 'Occupational Exposure', 'Risk Factors', "Workers' Compensation", 'Zimbabwe'] | 1,847,001 | [['D01.578.725.050', 'D01.837.725.700.760.070'], ['D01.524.500.050', 'D01.578.725.050.075', 'D01.578.725.500.050', 'D01.837.725.700.760.070.110', 'D01.837.725.700.760.535.400'], ['C08.381.483.581.125', 'C08.381.520.702.125', 'C24.800.127'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576.655.875.500'], ['N06... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Effects of insulin on glucose metabolism and glucose transport in fat cells of hormone-treated hypophysectomized rats: evidence that growth hormone restricts glucose transport. | In earlier studies we have shown that insulin does not stimulate glucose incorporation in adipocytes of hypophysectomized (hypox) rats. Basal glucose incorporation is decreased, although basal 3-O-methylglycose transport is very rapid and cannot be further stimulated by insulin. In this study we treated hypox rats with... | ['Adipose Tissue', 'Adrenocorticotropic Hormone', 'Animals', 'Biological Transport, Active', 'Cytochalasin B', 'Deoxyglucose', 'Dose-Response Relationship, Drug', 'Glucose', 'Growth Hormone', 'Hypophysectomy', 'Insulin', 'Kinetics', 'Male', 'Rats', 'Triiodothyronine'] | 226,351 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of genetic variants of the poly(ADP-ribose) polymerase-1 gene in breast cancer in French patients. | Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme that catalyzes the poly(ADP-ribosyl)ation of target proteins in response to DNA damage and has been proposed to play a role in DNA repair, recombination, transcription, cell death, cell proliferation, as well as in stabilization of the genome. We have recently ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Base Sequence', 'Breast Neoplasms', 'Carcinoma, Ductal', 'Case-Control Studies', 'DNA Mutational Analysis', 'Female', 'France', 'Genetic Testing', 'Humans', 'Middle Aged', 'Neoplasms, Hormone-Dependent', 'Poly (ADP-Ribose) Polymerase-1', 'Poly(ADP-ribose) Polymerases', 'Polymorph... | 17,560,163 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232', 'C04.557.470.615.132'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.393.760.700.300'], ['Z01... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Exploring shame, guilt, and risky substance use among sexual minority men and women. | This study examined the interrelations among shame-proneness, guilt-proneness, internalized heterosexism (IH), and problematic substance use among 389 gay, lesbian, and bisexual men and women. Problematic alcohol and drug use were positively related to shame-proneness and negatively related to guilt-proneness. Bisexual... | ['Adolescent', 'Adult', 'Alcoholism', 'Bisexuality', 'Female', 'Guilt', 'Homosexuality, Female', 'Homosexuality, Male', 'Humans', 'Illicit Drugs', 'Male', 'Minority Groups', 'Psychological Tests', 'Risk-Taking', 'Sexism', 'Shame', 'Substance-Related Disorders', 'Young Adult'] | 23,469,820 | [['M01.060.057'], ['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.145.802.975.200', 'G08.686.867.200'], ['F01.470.483'], ['F01.145.802.975.500.400', 'G08.686.867.500.400'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['I01.880.853.300'... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Knee arthrography: effects of various contrast media and epinephrine on synovial fluid. | Changes in synovial fluid leukocytes, total protein, and total complement were studied in 58 patients after they underwent single contrast material-enhanced knee arthrography with ionic (sodium iothalamate, sodium meglumine diatrizoate, meglumine iothalamate) and nonionic (iopamidol, iohexol) contrast media. In 30 of 5... | ['Adolescent', 'Adult', 'Arthrography', 'Complement System Proteins', 'Contrast Media', 'Diatrizoate Meglumine', 'Epinephrine', 'Humans', 'Iohexol', 'Iopamidol', 'Iothalamic Acid', 'Joint Diseases', 'Knee', 'Leukocyte Count', 'Middle Aged', 'Proteins', 'Synovial Fluid'] | 3,763,866 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.700.070'], ['D12.776.124.486.274'], ['D27.505.259.500', 'D27.720.259'], ['D02.033.800.813.550.500', 'D02.241.223.100.400.880.270.500', 'D02.455.426.559.389.127.375.880.270.500', 'D09.067.342.600.500', 'D09.853.813.550.500'], ['D02.033.100.291.310', 'D02.092.063.291.310',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sensitivity of toad rods: Dependence on wave-length and background illumination. | 1. There are five morphological types of photoreceptors in the retina of the toad, Bufo marinus: red and green rods, single cones, and the principal and accessory members of double cones. The largest and most abundant of these is the red rod. 2. Intracellular recordings were used to investigate the dependence of the se... | ['Adaptation, Ocular', 'Animals', 'Bufo marinus', 'Color Perception', 'Female', 'Light', 'Membrane Potentials', 'Neurons', 'Photoreceptor Cells', 'Retina', 'Retinal Pigments'] | 825,637 | [['G14.020'], ['B01.050'], ['B01.050.150.900.090.180.210.580'], ['F02.463.593.932.217'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A08.675', 'A11.671'], ['A08.675.650.850.625', 'A08.675.650.915.937', 'A08.800.950.937', 'A09.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine. | An observational, historical cohort evaluation was performed to examine the hypothesis that terfenadine (Seldane) exposure increases the risk of developing life-threatening ventricular arrhythmias. The study population consisted of Medicaid recipients from 4 states that were included in the Computerized On-Line Medical... | ['Adult', 'Age Factors', 'Aged', 'Arrhythmias, Cardiac', 'Clemastine', 'Cohort Studies', 'Death, Sudden, Cardiac', 'Disease', 'Drug-Related Side Effects and Adverse Reactions', 'Female', 'Heart Arrest', 'Humans', 'Ibuprofen', 'Information Systems', 'Male', 'Middle Aged', 'Nonprescription Drugs', 'Product Surveillance, ... | 8,109,548 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['D03.383.773.165'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.383.220', 'C23.550.260.322.250'], ['C23.550.288'], ['C25.100'], ['C14.280.383'], ['B01.050.150.900.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The pentafraction of hydroxyethyl starch inhibits ischemia-induced compartment syndrome. | Pentafraction (PF), a solution of biodegradable hydroxyethyl starch macromolecules with molecular weights of 10 to 100 x 10(4) daltons, has been shown to minimize tissue edema by sealing interendothelial clefts at the capillary level. The effect of PF on ischemia-reperfusion-induced compartment syndrome was studied. Te... | ['Analysis of Variance', 'Animals', 'Compartment Syndromes', 'Hydroxyethyl Starch Derivatives', 'Male', 'Rabbits', 'Reperfusion Injury', 'Time Factors'] | 7,518,011 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['C05.651.180', 'C14.907.303'], ['D09.301.915.500', 'D09.698.365.855.500'], ['B01.050.150.900.649.313.968.700'], ['C14.907.725', 'C23.550.767.877'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Conformational change of sodium- and potassium-dependent adenosine triphosphatase. Conformational evidence for the Post-Albers mechanism in Na+- and K+-dependent hydrolysis of ATP. | The addition of ATP with K+ to pig kidney Na+,K+-ATPase (EC 3.6.1.3) modified with a sulfhydryl fluorescent reagent N-[p-(2-benzimidazolyl)phenyl]maleimide induced a transient decrease (t 1/2 = 0.01 s) in the fluorescence in the presence of Mg2+ with 0.64 M Na+, followed by a slow increase (t 1/2 = 0.08 s), to give a h... | ['Animals', 'Hydrolysis', 'Kidney', 'Kinetics', 'Maleimides', 'Models, Biological', 'Protein Conformation', 'Sodium-Potassium-Exchanging ATPase', 'Spectrometry, Fluorescence', 'Sulfhydryl Reagents', 'Swine'] | 6,096,364 | [['B01.050'], ['G02.380'], ['A05.810.453'], ['G01.374.661', 'G02.111.490'], ['D02.241.081.337.502.524', 'D02.478.440', 'D03.383.129.578.399'], ['E05.599.395'], ['G02.111.570.820.709'], ['D08.811.277.040.025.314.750', 'D12.776.157.530.450.162.780', 'D12.776.157.530.450.250.880', 'D12.776.157.530.813.750', 'D12.776.543.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of endothelin on coronary flow, mechanical performance, oxygen uptake, and formation of purines and on outflow of prostacyclin in the isolated rabbit heart. | Endothelin is a 21-residue peptide formed during incubation of isolated porcine endothelial cells. Due to its pronounced vasoconstrictor activity, endothelin has been proposed to play a role in the regulation of vascular tone. We studied the effects of synthetic endothelin (0.1-10 nM) on coronary flow, mechanical perfo... | ['6-Ketoprostaglandin F1 alpha', 'Animals', 'Chromatography, Gas', 'Chromatography, Liquid', 'Coronary Circulation', 'Endothelins', 'Endothelium, Vascular', 'Female', 'Heart', 'Heart Rate', 'In Vitro Techniques', 'Male', 'Mass Spectrometry', 'Myocardium', 'Oxygen Consumption', 'Peptides', 'Purines', 'Rabbits'] | 2,403,862 | [['D10.251.355.255.550.400.350', 'D10.251.355.325.450', 'D23.469.050.175.725.400.350'], ['B01.050'], ['E05.196.181.349'], ['E05.196.181.400'], ['G09.330.100.324'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['A07.015.700.500', 'A10.272.491.355'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endoplasmic reticulum stress mediated apoptosis via JNK in MWCNT-exposed in vitro systems: size, surface functionalization and cell type specificity. | The aim of the present study was to evaluate the underlying mechanism of multi-walled carbon nanotubes (MWCNT) induced cellular response and their potential cross-talk, specifically, between endoplasmic reticulum (ER) stress, MAPK activation and apoptosis and how these nano-bio interactions depend on the physico-chemic... | ['Apoptosis', 'Cells, Cultured', 'Endoplasmic Reticulum Stress', 'Humans', 'JNK Mitogen-Activated Protein Kinases', 'Mitogen-Activated Protein Kinases', 'Nanotubes, Carbon'] | 32,493,873 | [['G04.146.954.035'], ['A11.251'], ['G04.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.567.374', 'D12.644.360.450.340', 'D12.776.476.450.340'], ['D08.811.913.696.620.682.700.567', 'D12.644.360.450', 'D12.776.476.450'], ['D01.268.150.250.500', 'J01.637.512.850.500']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Synaptonemal complex karyotype of zebrafish. | Meiotic cells of zebrafish have been prepared to show synaptonemal complexes (SCs) by light and electron microscopy. Completely paired SCs from both spermatocytes and oocytes were measured to produce an SC karyotype. The SC karyotype resembles the somatic karyotype of zebrafish and has no recognisable sex bivalent. Mea... | ['Animals', 'Chromosomes', 'Female', 'Karyotyping', 'Male', 'Meiosis', 'Recombination, Genetic', 'Sex Characteristics', 'Sex Chromosomes', 'Sex Determination Processes', 'Synaptonemal Complex', 'Zebrafish'] | 12,634,819 | [['B01.050'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['G04.144.220.220.687', 'G05.113.220.687'], ['G05.728'], ['G08.686.815'], ['A11.284.187.865', 'G05.360.162.865'], ['G05.813', 'G07.345.500.325.377.812', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA-Prot: identification of DNA binding proteins from protein sequence information using random forest. | DNA-binding proteins (DNABPs) are important for various cellular processes, such as transcriptional regulation, recombination, replication, repair, and DNA modification. So far various bioinformatics and machine learning techniques have been applied for identification of DNA-binding proteins from protein structure. Onl... | ['Algorithms', 'Amino Acids', 'DNA-Binding Proteins', 'Databases, Protein', 'Hydrophobic and Hydrophilic Interactions', 'Reproducibility of Results'] | 19,385,697 | [['G17.035', 'L01.224.050'], ['D12.125'], ['D12.776.260'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['G02.409'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effect of dried plums on colon cancer risk factors in rats. | Dried plums (that is, prunes) are a fruit that show promise as a food to lower colon cancer risk, based on their high content of dietary fiber and polyphenolics. In this study, we have examined the effect of diets containing dried plums on the number of colonic precancerous lesions (aberrant crypts, ACs), fecal bile ac... | ['Animals', 'Azoxymethane', 'Bile Acids and Salts', 'Cecum', 'Colonic Neoplasms', 'Dose-Response Relationship, Drug', 'Feces', 'Glucuronidase', 'Male', 'Nitroreductases', 'Oxidoreductases', 'Precancerous Conditions', 'Prunus', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Risk Factors'] | 16,351,514 | [['B01.050'], ['D02.172.080'], ['D04.210.500.105'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['G07.690.773.875', 'G07.690.936.500'], ['A12.459'], ['D08.811.277.450.426'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A review of Papanicolaou smears in a black hospital. | Results of 3,009 Papanicolaou smears from black women are reviewed. The modus operandi and cost for the outpatient component are presented. Abnormal results were reported in 11.6 percent of the combined outpatients and inpatients. The major portion of the changes in this subset were due to atypia present in a substanti... | ['African Continental Ancestry Group', 'Cervix Uteri', 'Female', 'Humans', 'Papanicolaou Test', 'Precancerous Conditions', 'Uterine Cervical Neoplasms', 'Vagina', 'Vaginal Neoplasms', 'Vaginal Smears'] | 3,712,481 | [['M01.686.508.100'], ['A05.360.319.679.256'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.384.100.422', 'E01.370.225.998.054.422', 'E04.074.422', 'E05.200.500.384.100.422', 'E05.200.998.054.422', 'E05.242.384.100.422'], ['C04.834'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An unusual pectate lyase from a Bacillus sp. with high activity on pectin: cloning and characterization. | The gene pelA encoding a pectate lyase from the strain Bacillus sp. BP-23 was cloned and expressed in Escherichia coli. The nucleotide sequence of a 1214 bp DNA fragment containing pelA gene was determined, revealing an ORF of 666 nucleotides that encoded a protein of 23233 Da. The deduced amino acid sequence of the en... | ['Amino Acid Sequence', 'Bacillus', 'Cloning, Molecular', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Genes, Bacterial', 'Molecular Sequence Data', 'Pectins', 'Polysaccharide-Lyases', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Substrate Specificity'] | 10,658,655 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['E05.393.220'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cutaneous drainage lymphatic map with interstitial multidetector-row computed tomographic lymphography using iopamidol: preliminary results. | We performed preliminary tests of the feasibility of multi-detector computed tomographic lymphography (MDCT-LG) with interstitial injection of iopamidol for mapping cutaneous lymphatic drainage pathways. MDCT-LG images were obtained following cutaneous injection of a total of 1ml iopamidol bilaterally into hind legs of... | ['Aged', 'Animals', 'Contrast Media', 'Dogs', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Iopamidol', 'Lymph Nodes', 'Lymphography', 'Melanoma', 'Middle Aged', 'Sentinel Lymph Node Biopsy', 'Skin', 'Skin Neoplasms', 'Tomography, X-Ray Computed'] | 17,853,616 | [['M01.060.116.100'], ['B01.050'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['D02.241.223.100.400.880.410', 'D02.455.426.559.389.127.375.880.410'], ['A10.549.400', 'A15.382.520.604.412'], ['E... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Gastrostomy placement improves height and weight gain in girls with Rett syndrome. | BACKGROUND: Growth failure and undernutrition complicate the clinical course of girls with Rett syndrome (RTT). These abnormalities are, in part, the consequence of oral motor dysfunction and inadequate dietary intake.OBJECTIVE: To determine whether gastrostomy placement for nutritional therapy alters the natural histo... | ['Adipose Tissue', 'Adolescent', 'Body Fluid Compartments', 'Body Height', 'Body Mass Index', 'Body Size', 'Body Weight', 'Child', 'Child, Preschool', 'Female', 'Fundoplication', 'Gastrostomy', 'Growth', 'Growth Disorders', 'Humans', 'Methyl-CpG-Binding Protein 2', 'Mutation', 'Nutritional Support', 'Rett Syndrome'] | 19,525,868 | [['A10.165.114'], ['M01.060.057'], ['A10.082', 'A12.207.180'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.1... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dental school deans' perceptions of the organizational culture and impact of the ELAM program on the culture and advancement of women faculty. | In 2006, deans of the sixty-four U.S. and Canadian dental schools were surveyed to gain their perspectives on their institutions' organizational culture for faculty, family-friendly policies, processes used by deans to develop faculty leadership, and the impact of the Executive Leadership in Academic Medicine (ELAM) Pr... | ['Administrative Personnel', 'Attitude of Health Personnel', 'Canada', 'Career Mobility', 'Dentists, Women', 'Education, Dental', 'Faculty, Dental', 'Female', 'Humans', 'Leadership', 'Male', 'Organizational Culture', 'Organizational Policy', 'Schools, Dental', 'Staff Development', 'United States', 'Women, Working', 'Wo... | 19,491,345 | [['M01.526.070'], ['F01.100.050', 'N05.300.100'], ['Z01.107.567.176'], ['N01.824.245.175', 'N01.824.547.330'], ['M01.526.485.330.310', 'M01.975.310', 'N02.360.330.310'], ['I02.358.274'], ['M01.526.485.360', 'M01.526.702.250.273', 'N02.360.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['N04.45... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of pulse duration of Er: YAG laser on dentin ablation. | The present study examined the effects on dentin ablation efficiency arising from various pulse durations of Er: YAG laser at a fixed energy fluence. Ten flat human dentin disks were prepared and exposed to an Er: YAG laser at 1 pps for three seconds at pulse durations of 100-500 microsec with 150 mJ/pulse (40.0 J/cm x... | ['Color', 'Dentin', 'Humans', 'Laser Therapy', 'Lasers, Solid-State', 'Microscopy, Confocal', 'Microscopy, Electron, Scanning', 'Smear Layer', 'Time Factors'] | 18,717,173 | [['G01.590.540.199'], ['A14.549.167.900.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['E07.632.490.490', 'E07.710.520.490'], ['E01.370.350.515.395', 'E05.595.395'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['C07.793.208.688'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis of novel triazoles and a tetrazole of escitalopram as cholinesterase inhibitors. | A novel serie of escitalopram triazoles (60-88) and a tetrazole (89) have been synthesized and subjected to a study to establish the inhibitory potential of these compounds toward acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Some selectivity in inhibition has been observed. The 4-chlorophenyl- (75, IC5... | ['Cholinesterase Inhibitors', 'Citalopram', 'Molecular Structure', 'Structure-Activity Relationship', 'Triazoles'] | 26,189,031 | [['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['D02.092.831.170', 'D02.626.320', 'D03.633.100.127.187'], ['G02.111.570', 'G02.466'], ['G02.111.830', 'G07.690.773.997'], ['D03.383.129.799']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alternative polyadenylation in glioblastoma multiforme and changes in predicted RNA binding protein profiles. | Alternative polyadenylation (APA) is widely present in the human genome and plays a key role in carcinogenesis. We conducted a comprehensive analysis of the APA products in glioblastoma multiforme (GBM, one of the most lethal brain tumors) and normal brain tissues and further developed a computational pipeline, RNAelem... | ['Base Sequence', 'Binding Sites', 'Brain', 'Brain Neoplasms', 'Cell Line, Tumor', 'Databases, Nucleic Acid', 'Glioblastoma', 'Heat-Shock Proteins', 'Humans', 'MADS Domain Proteins', 'MEF2 Transcription Factors', 'Myogenic Regulatory Factors', 'Neoplasm Proteins', 'Polyadenylation', 'Polycomb Repressive Complex 1', 'RN... | 23,421,905 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A11.251.210.190', 'A11.251.860.180'], ['L01.313.500.750.300.188.400.300.500', 'L01.313.500.750.300.188.400.325.630', 'L01.470.750.750.300.500', 'L01.470.750.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Grandmother's support for new mothers in Japan. | OBJECTIVES: This study was designed to describe grandmothers' intentions regarding providing satisfactory infant care support for new mothers.DESIGN AND SAMPLE: Qualitative inductive analysis was performed using semistructured interviews conducted with 19 pairs of grandmothers and new mothers with one child aged 3-4 mo... | ['Adult', 'Aged', 'Child', 'Female', 'Grandparents', 'Humans', 'Infant', 'Infant Care', 'Intergenerational Relations', 'Japan', 'Middle Aged', 'Mothers'] | 29,770,966 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['F01.829.263.403', 'I01.880.853.150.452', 'M01.264'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['N02.421.088.120'], ['F01.829.263.370.110', 'F01.829.401.190'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['F01.829.263.500.320... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Activation of respiratory muscles during weaning from mechanical ventilation. | PURPOSE: Respiratory muscle dysfunction is a key component of weaning failure. Balancing respiratory muscle loading and unloading by applying different ventilation modes along with spontaneous breathing episodes are established weaning strategies. However, the effects of body positioning on the respiratory muscles duri... | ['Adult', 'Aged', 'Aged, 80 and over', 'Diaphragm', 'Electromyography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oximetry', 'Patient Positioning', 'Pulmonary Gas Exchange', 'Respiration, Artificial', 'Respiratory Muscles', 'Treatment Outcome', 'Ventilator Weaning'] | 27,951,475 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.633.567.900.300'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.386.700.100.600', 'E05.200.124.100.100.600'], ['E02.760.6... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Toll-like receptor 3 agonist protection against experimental Francisella tularensis respiratory tract infection. | We investigated whether Toll-like receptor 3 (TLR3) stimulation would protect the host from inhaled Francisella tularensis. TLR3 is expressed by respiratory epithelial cells and macrophages and can be activated by a synthetic double-stranded RNA ligand called polyinosine-polycytosine [poly(I:C)]. Thus, we evaluated pol... | ['Animals', 'Anti-Bacterial Agents', 'Bronchoalveolar Lavage Fluid', 'Cells, Cultured', 'Colony Count, Microbial', 'Cytokines', 'Female', 'Francisella tularensis', 'Humans', 'Immunologic Factors', 'Levofloxacin', 'Lung', 'Mice', 'Mice, Inbred BALB C', 'Monocytes', 'Neutrophils', 'Ofloxacin', 'Poly I-C', 'Respiratory Tr... | 20,123,717 | [['B01.050'], ['D27.505.954.122.085'], ['E05.927.100.500'], ['A11.251'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B03.440.400.425.340.590', 'B03.660.250.200.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477'], ['D03.633.100.810.835.322.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Research plan for developing trauma core competencies for nurses in Thailand. | The aim of this research plan was identification and development of core competencies for emergency trauma nurses in Thailand. The research plan was undertaken in three phases. Phase I: a national survey of the critical dimensions of care; Phase II: development of a 64 item tool; and Phase III: efficiency study with em... | ['Analysis of Variance', 'Attitude of Health Personnel', 'Clinical Competence', 'Education, Nursing, Continuing', 'Educational Measurement', 'Emergency Nursing', 'Employee Performance Appraisal', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Needs Assessment', "Nurse's Role", 'Nursing Education Research', 'Nursin... | 20,129,437 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.212.450', 'I02.358.462.399'], ['I02.399'], ['H02.478.676.200', 'N02.421.533.200'], ['N04.452.677.370'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Nuclear matrix-like filaments and fibrogranular complexes form through the rearrangement of specific nuclear ribonucleoproteins. | The behavior of nuclear pre-mRNA-binding proteins after their nuclease and/or salt-induced release from RNA was investigated. After RNase digestion or salt extraction, two proteins that initially exist as tetramers (A2)(3)B1 in isolated heterogeneous nuclear ribonucleoprotein (hnRNP) complexes quantitatively reassociat... | ['Actin Cytoskeleton', 'Animals', 'Cell Line', 'Cell Nucleus', 'Disulfides', 'Humans', 'Mice', 'Rats', 'Ribonucleases', 'Ribonucleoproteins', 'Sodium Chloride', 'Solubility'] | 10,793,134 | [['A11.284.430.214.190.750.050'], ['B01.050'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.7... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stegmann Canal Expander for canaloplasty: A novel technique. | INTRODUCTION: The concept of canaloplasty is to increase aqueous egress through all structures that control the aqueous outflow, such as the trabecular meshwork, Schlemm's canal, and collector channels, by viscomodulation and by placing of a suture stent into the canal. Clinical studies show canaloplasty to be safe and... | ['Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Microscopy, Acoustic', 'Prospective Studies', 'Sclera', 'Surgical Flaps', 'Sutures', 'Tissue Expansion Devices', 'Trabecular Meshwork'] | 29,973,071 | [['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E01.370.350.515.370', 'E01.370.350.850.565', 'E05.595.370'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['A09.371.784'], ['A10.850.710', 'E07.862.710'], ['E07.858.690.820'], ['E07.695.80... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Competitive athletes with implantable cardioverter-defibrillators-How to program? Data from the Implantable Cardioverter-Defibrillator Sports Registry. | BACKGROUND: Athletes with an implantable cardioverter-defibrillator (ICD) may require unique optimal device-based tachycardia programming.OBJECTIVE: The purpose of this study was to assess the association of tachycardia programming characteristics of ICDs with occurrence of shocks, transient loss-of-consciousness, and ... | ['Adolescent', 'Adult', 'Athletes', 'Child', 'Death, Sudden, Cardiac', 'Defibrillators, Implantable', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Registries'] | 30,389,442 | [['M01.060.057'], ['M01.060.116'], ['M01.072'], ['M01.060.406'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.45... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MacroH2A suppresses the proliferation of the B16 melanoma cell line. | MacroH2A is the most frequently altered histone, which participates in cancer progression. Increasing evidence demonstrates that cancer progression could be regulated by macroH2A by affecting the cell cycle. In the present study, it was demonstrated that macroH2A suppresses melanoma cell progression and the molecular m... | ['Animals', 'Cell Line, Tumor', 'Cyclin D1', 'Cyclin D3', 'Cyclin-Dependent Kinase 4', 'Cyclin-Dependent Kinase 6', 'Cyclin-Dependent Kinase 8', 'G2 Phase Cell Cycle Checkpoints', 'Histones', 'M Phase Cell Cycle Checkpoints', 'Melanoma, Experimental', 'Mice', 'RNA Interference', 'RNA, Messenger', 'RNA, Small Interferin... | 25,119,498 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D12.644.360.262.150.300', 'D12.776.167.218.150.300', 'D12.776.476.262.150.300'], ['D08.811.913.696.620.682.700.646.500.875', 'D12.644.360.250.451', 'D12.7... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of laparoscopic percutaneous extraperitoneal closure versus conventional herniotomy in extremely low birth weight infants. | PURPOSE: Laparoscopic percutaneous extraperitoneal closure (LPEC) has become routine for repairing pediatric inguinal hernia (IH). Reports on the effective repair of IH in challenging cases, such as extremely low birth weight infants (ELBWI) who become symptomatic soon after birth and have surgery before 1 year of age,... | ['Child, Preschool', 'Female', 'Hernia, Inguinal', 'Herniorrhaphy', 'Humans', 'Infant', 'Infant, Extremely Low Birth Weight', 'Laparoscopy', 'Male', 'Operative Time', 'Postoperative Period', 'Recurrence', 'Treatment Outcome'] | 30,390,137 | [['M01.060.406.448'], ['C23.300.707.374.875'], ['E04.680.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520.460.600.500'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['E04.614.750', 'N02.421.585.753.750'], ['C23.550.291.937'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oesophageal varices associated with busulphan-thioguanine combination therapy for chronic myeloid leukaemia. | 5 patients receiving continuous busulphan and 6-thioguanine for chronic myeloid leukaemia (CML) were found to have oesophageal varices associated with abnormal liver function tests. 3 of these cases presented with gastrointestinal haemorrhage and 1 patient died. The 2 other cases had varices discovered at endoscopy. No... | ['Adult', 'Aged', 'Aged, 80 and over', 'Busulfan', 'Drug Therapy, Combination', 'Esophageal and Gastric Varices', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Hyperplasia', 'Leukemia, Myeloid', 'Liver', 'Male', 'Middle Aged', 'Thioguanine'] | 2,889,964 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.033.455.125.125', 'D02.455.326.146.100.050.500.100', 'D02.886.645.600.055.050.510.100'], ['E02.319.310'], ['C06.405.117.240', 'C06.552.494.414'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modified catheter for percutaneous gastrojejunostomy. | A catheter for gastrojejunostomy was modified to include a Cope-loop retention device in the proximal part of the catheter and multiple side holes in the distal part. The modification was made to prevent catheter dislodgment, which can lead to infusion of feeding solution into the peritoneum. The catheter has been used... | ['Adult', 'Aged', 'Aged, 80 and over', 'Catheterization', 'Enteral Nutrition', 'Female', 'Gastrostomy', 'Humans', 'Jejunostomy', 'Male', 'Middle Aged'] | 2,506,611 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148', 'E05.157'], ['E02.421.360', 'E02.642.500.360'], ['E04.210.496', 'E04.579.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.523', 'E04.579.338.523'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The safety and efficacy of antitumour necrosis factor-alpha therapy for inflammatory bowel disease in patients post liver transplantation: a case series. | BACKGROUND: The role of antitumour necrosis factor-alpha (anti-TNF) therapy for inflammatory bowel disease (IBD) among liver transplant recipients is largely unknown given the rarity of this population and the paucity of literature on the subject.AIM: To investigate the safety and efficacy of anti-TNF therapy for refra... | ['Adult', 'Aged', 'Antibodies, Monoclonal', 'Female', 'Gastrointestinal Agents', 'Humans', 'Inflammatory Bowel Diseases', 'Infliximab', 'Liver Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Treatment Outcome', 'Tumor Necrosis Factor-alpha'] | 22,616,981 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.205.731', 'C06.405.469.432'], ['D12.776.124.486.485.114.224.608', 'D12.776.124.790.651.114.224.537', 'D12.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reducing childhood obesity through U.S. federal policy: a microsimulation analysis. | BACKGROUND: Childhood obesity prevalence remains high in the U.S., especially among racial/ethnic minorities and low-income populations. Federal policy is important in improving public health given its broad reach. Information is needed about federal policies that could reduce childhood obesity rates and by how much.PU... | ['Adolescent', 'Carbonated Beverages', 'Child', 'Female', 'Health Policy', 'Humans', 'Male', 'Motor Activity', 'Pediatric Obesity', 'Prevalence', 'Program Evaluation', 'School Health Services', 'Taxes', 'United States'] | 25,175,764 | [['M01.060.057'], ['G07.203.100.300', 'J02.200.300'], ['M01.060.406'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['C18.654.726.500.720', 'C23.888.144.699.500.750', 'E01.370.600.115.100.160.120.699.500.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'G... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
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