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A comparison of methods for the isolation of salmonellae from sewage sludge. | Methods for the isolation of salmonellae from sewage sludge were compared. Buffered peptone water and lactose broth were compared to determine their efficiencies as preenrichment media and temperature and duration of incubation were also investigated. In addition five enrichment and five plating media were compared tog... | ['Bacteriological Techniques', 'Humans', 'Salmonella', 'Sewage', 'Soil Microbiology', 'Water Microbiology'] | 6,377,754 | [['E01.370.225.875.150', 'E05.200.875.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.450.425.800', 'B03.660.250.150.710'], ['D20.944.932.500'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Interaction between macrophages and aortic smooth muscle cells. Enhancement of cholesterol esterification in smooth muscle cells by media of macrophages incubated with acetylated LDL. | Mouse peritoneal macrophages were cultured for 24 h in Dulbecco-Vogt medium containing 10% calf serum. This medium was replaced with Dulbecco-Vogt medium containing 1% bovine serum albumin to which all subsequent additions were made. Medium changes, accompanied by appropriate additions, were made every 48 or 72 h and t... | ['Acylation', 'Animals', 'Aorta', 'Cattle', 'Cells, Cultured', 'Cholesterol Esters', 'Humans', 'Kinetics', 'Lipoproteins, LDL', 'Macrophages', 'Male', 'Mice', 'Muscle, Smooth, Vascular', 'Rats'] | 7,295,747 | [['G02.111.012', 'G02.607.063', 'G03.040'], ['B01.050'], ['A07.015.114.056'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D10.532.515', 'D12... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Excellent activity of newer quinolones on Legionella pneumophila in J774 macrophages. | The activity of six antibiotics directed against intracellularly multiplying Legionella pneumophilia was examined in tissue cultures with J774 macrophages. The drugs tested were the new quinolones, BAY Y 3118 and clinafloxacin, and ciprofloxacin, erythromycin, gentamicin and ampicillin served as reference drugs. Additi... | ['Ampicillin', 'Animals', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Bacteriological Techniques', 'Ciprofloxacin', 'Colony Count, Microbial', 'Erythromycin', 'Fluoroquinolones', 'Gentamicins', 'Legionella pneumophila', "Legionnaires' Disease", 'Macrophages', 'Mice', 'Penicillins', 'Quinolones', 'Tumor Cells, Cu... | 9,084,116 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['B01.050'], ['D27.505.954.122.085'], ['D27.505.954.122'], ['E01.370.225.875.150', 'E05.200.875.150'], ['D03.633.100.810.835.322.186'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D02.540.576.500.992'], ['D03.633.100.810.835.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An induced current method for measuring zeta potential of electrolyte solution-air interface. | This paper reports a novel and very simple method for measuring the zeta potential of electrolyte solution-air interface. When a measuring electrode contacts the electrolyte solution-air interface, an electrical current will be generated due to the potential difference between the electrode-air surface and the electrol... | ['Air', 'Calcium Chloride', 'Electricity', 'Electrochemical Techniques', 'Electrodes', 'Electrolytes', 'Magnesium Chloride', 'Sodium Chloride', 'Solutions', 'Water'] | 24,370,408 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['D01.146.300', 'D01.210.450.150.150'], ['G01.358.500.249'], ['E05.301'], ['E07.305.250'], ['D01.248'], ['D01.210.450.150.500', 'D01.524.475'], ['D01.210.450.150.875', 'D01.857.650'], ['D26.776'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Paradoxes of GP fundholding: contracting for community health services in the British National Health Service. | The expansion of GP fundholding (GPFH) is central to the British government's attempt to maintain the revolution under way in the National Health Service (NHS). Evaluations of the NHS reforms have portrayed GPFH as an important mechanism for competition, and GPFH's bargaining power is reported to have secured significa... | ['Attitude of Health Personnel', 'Community Health Services', 'Competitive Bidding', 'Family Practice', 'Health Policy', 'Humans', 'State Medicine', 'United Kingdom'] | 9,428,087 | [['F01.100.050', 'N05.300.100'], ['N02.421.143'], ['N03.219.463.100.110'], ['H02.403.340.500'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Who multi-tasks and why? Multi-tasking ability, perceived multi-tasking ability, impulsivity, and sensation seeking. | The present study examined the relationship between personality and individual differences in multi-tasking ability. Participants enrolled at the University of Utah completed measures of multi-tasking activity, perceived multi-tasking ability, impulsivity, and sensation seeking. In addition, they performed the Operatio... | ['Adolescent', 'Adult', 'Executive Function', 'Female', 'Humans', 'Impulsive Behavior', 'Individuality', 'Male', 'Personality Inventory', 'Risk-Taking', 'Self Efficacy', 'Self Report', 'Sensation', 'Task Performance and Analysis'] | 23,372,720 | [['M01.060.057'], ['M01.060.116'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.527'], ['F01.752.488'], ['F04.711.647.513'], ['F01.145.722'], ['F01.752.747.792.700'], ['E05.318.308.980.500', 'N05.715.360.300.800.500', 'N06.850.520.308.980.500'], ['F02.830.816', 'G11.561.790'], ['F02.784.4... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The resistance to change of observing. | Observing responses produce contact with discriminative stimuli and have been considered analogous to attending. Many studies have examined the effects of reinforcement rate on the resistance to change of simple operant behavior, but nothing is known about the resistance to change of observing. Two experiments examined... | ['Animals', 'Appetitive Behavior', 'Association Learning', 'Attention', 'Color Perception', 'Columbidae', 'Discrimination Learning', 'Extinction, Psychological', 'Motivation', 'Orientation', 'Pattern Recognition, Visual', 'Reinforcement Schedule'] | 14,964,708 | [['B01.050'], ['F01.145.113.111'], ['F02.463.425.069.296'], ['F02.830.104.214'], ['F02.463.593.932.217'], ['B01.050.150.900.248.165.150'], ['F02.463.425.280'], ['F02.463.425.770.232'], ['F01.658', 'F01.752.543.500.750'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.425.770.6... | ['Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development and application of a high-performance liquid chromatography method using monolithic columns for the analysis of ecstasy tablets. | A rapid and selective HPLC method using monolithic columns was developed for the separation and quantification of the principal amphetamines in ecstasy tablets. Three monolithic (Chromolith RP18e) columns of different lengths (25, 50 and 100 mm) were assessed. Validation studies including linearity, selectivity, precis... | ['3,4-Methylenedioxyamphetamine', 'Chromatography, High Pressure Liquid', 'Hallucinogens', 'N-Methyl-3,4-methylenedioxyamphetamine', 'Reference Standards', 'Reproducibility of Results', 'Spectrophotometry, Ultraviolet', 'Tablets', 'Technology, Pharmaceutical'] | 16,466,734 | [['D02.092.471.683.152.660'], ['E05.196.181.400.300'], ['D27.505.696.388', 'D27.505.954.427.700.372'], ['D02.092.471.683.152.670'], ['E05.978.808'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D26.255.830'], ['E05.916', 'J01.897.836... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Admixture analysis of plasma cholesterol levels in a Jewish population sample in Jerusalem. | The frequency distribution of total plasma cholesterol levels (TC) in 17-year-old Jerusalem youngsters and their parents (n = 6,170) was examined for evidence of admixture of normal distributions. Probability plots indicated bimodality of age-adjusted TC in both sexes. Using a maximum likelihood procedure, two normal d... | ['Adolescent', 'Adult', 'Cholesterol', 'Female', 'Humans', 'Israel', 'Jews', 'Lipoproteins, HDL', 'Male', 'Middle Aged', 'Triglycerides'] | 6,745,957 | [['M01.060.057'], ['M01.060.116'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['M01.686.754.600'], ['D10.532.432', 'D12.776.521.479'], ['M01.060.116.630'], ['D10.351.801']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[Megaloblastic anemia and platelet function--a qualitative platelet defect in pernicious anemia]. | In order to know the entities of platelet defect in pernicious anemia, we investigated platelet functions in ten cases with pernicious anemia. Three of the cases had total gastrectomy. Five cases showed thrombocytopenia and four cases revealed prolongation of Ivy bleeding time. Decreased adhesiveness was observed in th... | ['Adult', 'Aged', 'Anemia, Macrocytic', 'Anemia, Megaloblastic', 'Anemia, Pernicious', 'Blood Platelets', 'Female', 'Humans', 'Male', 'Middle Aged', 'Platelet Aggregation', 'Platelet Storage Pool Deficiency'] | 2,329,689 | [['M01.060.116'], ['M01.060.116.100'], ['C15.378.071.252'], ['C15.378.071.252.196'], ['C15.378.071.252.196.500', 'C18.654.521.500.133.699.923.280'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.188.370.687', 'G09.188.390.600.640'], ['C15.378.100.685', '... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of magnesium coating on bone-implant interfaces with and without polyether-ether-ketone particle interference: A rabbit model based on porous Ti6Al4V implants. | We investigated the effects of magnesium (Mg) on osteogenesis and bone resorption at a porous structure interface. A three-dimensional (3D)-printed porous Ti6Al4V implant coated with Mg was introduced, and polyether-ether-ketone wear particles were added to generate an animal model of implant loosening. We also examine... | ['Animals', 'Bone-Implant Interface', 'Cell Differentiation', 'Coated Materials, Biocompatible', 'Humans', 'Implants, Experimental', 'Ketones', 'Magnesium', 'Materials Testing', 'Osteoclasts', 'Osteogenesis', 'Polyethylene Glycols', 'Printing, Three-Dimensional', 'Rabbits', 'Titanium'] | 30,684,307 | [['B01.050'], ['A02.835.232.022', 'A10.165.265.183', 'E07.695.125'], ['G04.152'], ['D25.130.420', 'J01.637.051.130.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.340'], ['D02.522'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E05.570'], ['A11.329.372.700', 'A11.627.482.700'], ['G07.3... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Analysis on Two Typical Landslide Hazard Phenomena in The Wenchuan Earthquake by Field Investigations and Shaking Table Tests. | Based on our field investigations of landslide hazards in the Wenchuan earthquake, some findings can be reported: (1) the multi-aspect terrain facing empty isolated mountains and thin ridges reacted intensely to the earthquake and was seriously damaged; (2) the slope angles of most landslides was larger than 45°. Consi... | ['China', 'Disasters', 'Earthquakes', 'Landslides', 'Risk Assessment'] | 26,258,785 | [['Z01.252.474.164'], ['N06.230.100'], ['G01.311.250', 'N06.230.100.230.200'], ['G01.311.603', 'N06.230.100.230.625'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715']] | ['Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Angiographic diagnosis and treatment of posttraumatic carotid-cavernous fistulas. | Balloon embolization was attempted in 7 patients with posttraumatic carotid-cavernous fistulas. The procedure was successful in 4 patients and failed in 3 other. Two of these fistulas showed spontaneous regression after failed embolization. In one patient, premature detachment of the balloon led to cerebral infarction,... | ['Angiography', 'Arteriovenous Fistula', 'Carotid Arteries', 'Catheterization', 'Cavernous Sinus', 'Craniocerebral Trauma', 'Embolization, Therapeutic', 'Humans', 'Vision Disorders'] | 2,488,453 | [['E01.370.350.700.060', 'E01.370.370.050'], ['C14.240.850.750.147', 'C14.240.850.984.750', 'C14.907.150.125', 'C14.907.933.555', 'C16.131.240.850.750.125', 'C23.300.575.950.250'], ['A07.015.114.186'], ['E02.148', 'E05.157'], ['A07.015.908.224.334'], ['C10.900.300', 'C26.915.300'], ['E02.520.360', 'E02.926.500'], ['B01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ST-segment elevation resolution in lead aVR: a strong predictor of adverse outcomes in patients with non-ST-segment elevation acute coronary syndrome. | BACKGROUND: The impact of ST-segment elevation resolution in lead aVR on outcomes in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) is unclear.METHODS AND RESULTS: Electrocardigrams (ECGs) were recorded on admission and 6 h later in 367 patients with NSTE-ACS. ST-segment deviation >or=0.5 mm... | ['Acute Coronary Syndrome', 'Adult', 'Aged', 'Aged, 80 and over', 'Coronary Angiography', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Myocardial Revascularization', 'Predictive Value of Tests', 'Prognosis', 'Retrospective Studies', 'Treatment Outcome', 'Triage', 'Troponin... | 18,577,810 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E0... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of Age and Noise Exposure on Proxy Measures of Cochlear Synaptopathy. | Although there is strong histological evidence for age-related synaptopathy in humans, evidence for the existence of noise-induced cochlear synaptopathy in humans is inconclusive. Here, we sought to evaluate the relative contributions of age and noise exposure to cochlear synaptopathy using a series of electrophysiolog... | ['Acoustic Stimulation', 'Adult', 'Age Factors', 'Audiometry, Pure-Tone', 'Auditory Threshold', 'Cochlea', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Hearing Loss, Noise-Induced', 'Humans', 'Male', 'Middle Aged', 'Noise', 'Speech Perception'] | 31,558,119 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.382.375.060.055'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['A09.246.300.246'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['C09.218.458.341.887.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mutations in the nucleotide binding domain of the alpha subunits of the F1-ATPase from thermophilic Bacillus PS3 that affect cross-talk between nucleotide binding sites. | Inactivation of MF1 (bovine mitochondrial F1-ATPase) with 5'-p-fluorosulfonylbenzoylethenoadenosine is caused by labeling alpha Y244 [Verburg, J. G., and Allison, W. S. (1990) J. Biol. Chem. 265, 8065-8074]. In the crystal structure [Abrahams, J.P., Leslie, A. G. W., Lutter, R., and Walker, J. E. (1994) Nature 370, 621... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Aluminum', 'Arginine', 'Bacillus', 'Bacterial Proteins', 'Binding Sites', 'Cysteine', 'Fluorine', 'Hydrolysis', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Phenylalanine', 'Proton-Translocating ATPases', 'Structure-Activity Relationship', 'Tyrosine'] | 9,454,591 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D01.268.557.050', 'D01.552.547.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.10... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elderly people at home disabled by chronic obstructive pulmonary disease. | BACKGROUND: We compared uptake of hospital and community-based support in elderly people disabled by chronic obstructive pulmonary disease (COPD), normal controls (NCs) and patients with Parkinsons disease, stroke, amputation, or arthritis (disabled controls; DCs).METHODS: There were 65 subjects (35 men) aged 70-93 yea... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Disabled Persons', 'Female', 'Home Care Services', 'Humans', 'Lung Diseases, Obstructive', 'Male'] | 9,884,013 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.150'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of aging and beta-amyloid on the properties of brain synaptic and mitochondrial membranes. | The effects of aging and of different amyloid beta-peptides (A beta) on the properties of purified synaptosomal plasma and mitochondrial membranes were studied using different fluorescent dyes. Aging led to opposite membrane alterations in both mouse brain fractions. Cholesterol levels were significantly enhanced in sy... | ['Aging', 'Alzheimer Disease', 'Amyloid beta-Peptides', 'Animals', 'Brain', 'Cholesterol', 'Diphenylhexatriene', 'Fatty Acids', 'Female', 'Fluorescence Polarization', 'Fluorescent Dyes', 'Intracellular Membranes', 'Membrane Lipids', 'Mice', 'Mice, Inbred Strains', 'Mitochondria', 'Pyrenes', 'Synaptic Membranes', 'Synap... | 11,716,141 | [['G07.345.124'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['A08.186.211'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D02.455.326.271.665.250'], ['D10.251'], ['E05.196.712.516.600.390... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of 2 generational improvements in colonoscopes on adenoma miss rates: results of a prospective randomized multicenter tandem study. | BACKGROUND AND AIMS: Numerous randomized studies have shown that changing certain features of colonoscopes, usually incorporated when switching from one endoscope generation to the next, mostly do not increase adenoma yield. There is, however, indirect evidence that it may be necessary to skip one instrument generation... | ['Adenoma', 'Adenomatous Polyps', 'Adult', 'Aged', 'Colonic Polyps', 'Colonoscopes', 'Colonoscopy', 'Colorectal Neoplasms', 'Diagnostic Errors', 'Equipment Design', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies'] | 29,410,020 | [['C04.557.470.035'], ['C04.557.470.035.215'], ['M01.060.116'], ['M01.060.116.100'], ['C23.300.825.411.235'], ['E07.230.220.260.160', 'E07.858.240.260.160'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', '... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Polymorphism in apolipoprotein(a) kringle IV 37(Met/Thr): frequency in a London population and its association with coronary artery disease. | BACKGROUND: A raised concentration of lipoprotein(a) [Lp(a)] in human plasma has been considered as a risk factor for coronary artery disease (CAD). Apolipoprotein(a) and plasminogen genes are exceptionally similar to a variable number of plasminogen-like kringle IV repeats in the apo(a) gene. Polymorphisms have been p... | ['Aged', 'Apolipoproteins A', 'Coronary Disease', 'Female', 'Gene Frequency', 'Genotype', 'Humans', 'London', 'Male', 'Middle Aged', 'Point Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Prevalence', 'Risk Factors'] | 9,377,824 | [['M01.060.116.100'], ['D10.532.091.200', 'D12.776.070.400.200', 'D12.776.521.120.200'], ['C14.280.647.250', 'C14.907.585.250'], ['G05.330'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.433.553', 'Z01.542.363.300.553'], ['M01.060.116.630'], ['G05.365.590.675'], ['E05.393.620.500'], ['G05.365.795... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A Dyadic Analysis on Source Discrepancy and a Mediation Analysis via Self-Efficacy in the Parental Support and Physical Activity Relationship among Black Girls. | BACKGROUND: Physical activity (PA) declines in adolescence among black girls. This study assesses how moderate/vigorous physical activity (MVPA) relates to caregiver- vs. adolescent-reported parental support and whether the relationship is mediated by self-efficacy.METHODS: MVPA was assessed through accelerometry. Pare... | ['African Americans', 'Child', 'Cross-Sectional Studies', 'Exercise', 'Female', 'Humans', 'Parents', 'Pediatric Obesity', 'Self Efficacy', 'Social Support', 'Surveys and Questionnaires'] | 30,653,347 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['C18.654.726.500.720', 'C23.88... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Feasibility study of semi-selective protein precipitation with salt-tolerant copolymers for industrial purification of therapeutic antibodies. | We present a feasibility study for an antibody capturing process from clarified cell culture fluid using semi-selective protein precipitation with salt-tolerant copolymers. Protein precipitation is mediated by hydrophobic and electrostatic interactions with the copolymer that can be customized for the respective target... | ['Animals', 'Antibodies', 'Biological Products', 'Cell Culture Techniques', 'Cell Line', 'Chemical Fractionation', 'Chemical Precipitation', 'Feasibility Studies', 'Hydrogen-Ion Concentration', 'Recombinant Proteins', 'Salts', 'Technology, Pharmaceutical'] | 23,637,026 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D20.215'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210'], ['E05.196.155'], ['E05.196.150', 'G02.159'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Location and characterization of two functions on RP1 that inhibit the fertility of the IncW plasmid R388. | Two fertility-inhibition functions which reduce R388 (IncW) transfer were detected on RP1 (60 kb, IncP). The respective genes, fiwA and fiwB, were mapped by transposon insertion mutagenesis to the regions between coordinates 32.8 to 31.7 kb (fiwA), and 59.8 to 0.8 kb (fiwB). The fiwA function occurs in a non-essential ... | ['DNA Transposable Elements', 'Escherichia coli', 'Fertility', 'Genes, Bacterial', 'Mutation', 'Phenotype', 'R Factors'] | 2,559,940 | [['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G08.686.210'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.365.590'], ['G05.695'], ['G05.360.600.600']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Male patients with rheumatoid arthritis have an increased risk of osteoporosis: Frequency and risk factors. | Most previous research investigating osteoporosis in rheumatoid arthritis (RA) has focused on female patients and there is a lack of data regarding clinical characteristics of osteoporosis in male patients with RA.The aim of this study was to compare the frequency of osteoporosis between male patients with RA and healt... | ['Absorptiometry, Photon', 'Aged', 'Arthritis, Rheumatoid', 'Bone Density', 'Cross-Sectional Studies', 'Humans', 'Male', 'Middle Aged', 'Osteoporosis', 'Republic of Korea', 'Retrospective Studies', 'Risk Factors'] | 29,901,636 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G11.427.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.116.198.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The alignment of sets of sequences and the construction of phyletic trees: an integrated method. | In this paper we argue that the alignment of sets of sequences and the construction of phyletic trees cannot be treated separately. The concept of 'good alignment' is meaningless without reference to a phyletic tree, and the construction of phyletic trees presupposes alignment of the sequences. We propose an integrated... | ['Base Sequence', 'Biological Evolution', 'Prokaryotic Cells', 'RNA, Ribosomal'] | 6,433,036 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['A11.760'], ['D13.444.735.686']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
SDF-2 induction of terminal differentiation in Dictyostelium discoideum is mediated by the membrane-spanning sensor kinase DhkA. | SDF-2 is a peptide released by prestalk cells during culmination that stimulates prespore cells to encapsulate. Genetic evidence indicates that the response is dependent on the dhkA gene. This gene encodes a member of the histidine kinase family of genes that functions in two-component signal transduction pathways. The... | ['Animals', 'Catalytic Domain', 'Cell Differentiation', 'Cell Membrane', 'Dictyostelium', 'Intercellular Signaling Peptides and Proteins', 'Membrane Proteins', 'Mutagenesis, Site-Directed', 'Peptides', 'Phosphorylation', 'Protein Kinases', 'Proteins', 'Protozoan Proteins', 'Recombinant Fusion Proteins'] | 10,373,524 | [['B01.050'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['G04.152'], ['A11.284.149'], ['B01.046.550.200.300'], ['D12.644.276', 'D12.776.467', 'D23.529'], ['D12.776.543'], ['E05.393.420.601.575'], ['D12.644'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D08.811.913.696.620.682'], ['D12.776'], ['D12.77... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Children's emotional and physiological responses to interadult angry behavior: the role of history of interparental hostility. | Relations between history of marital discord and responses to interadult angry behavior were examined in preschoolers. Children watched/listened to an angry interaction between two adults, while their heart rate (HR) and skin conductance response (SCR) and skin conductance level (SCL) were monitored; then they were int... | ['Child Behavior', 'Child, Preschool', 'Conflict, Psychological', 'Family', 'Female', 'Galvanic Skin Response', 'Heart Rate', 'Hostility', 'Humans', 'Male', 'Parents', 'Psychology, Child', 'Sex Factors'] | 7,876,455 | [['F01.145.179'], ['M01.060.406.448'], ['F01.658.209'], ['F01.829.263', 'I01.880.853.150'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['E01.370.600.875.500', 'G09.330.380.500'], ['F01.470.596'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice. | A deficiency in essential fatty acid metabolism has been reported in plasma from patients with cystic fibrosis (CF). However, its etiology and role in the expression of disease is unknown. The objective of this study was to determine whether alterations in fatty acid metabolism are specific to CF-regulated organs and w... | ['Administration, Oral', 'Animals', 'Arachidonic Acid', 'Cystic Fibrosis', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Docosahexaenoic Acids', 'Ileum', 'Intestinal Absorption', 'Lipopolysaccharides', 'Liver', 'Lung', 'Membrane Lipids', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Pancreas', 'Phenotype',... | 10,570,187 | [['E02.319.267.100'], ['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changing academic culture to improve undergraduate STEM education. | Improving undergraduate science, technology, engineering, and math (STEM) education requires faculty with the skills, resources, and time to create active learning environments that foster student engagement. Current faculty hiring, promotion, and tenure practices at many universities do not measure, reward, nor encour... | ['Engineering', 'Faculty', 'Mathematics', 'Science', 'Technology', 'Universities'] | 25,449,051 | [['J01.293'], ['M01.526.702.250'], ['H01.548'], ['H01.770'], ['J01.897'], ['I02.783.830', 'J03.832.830']] | ['Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 |
[Thymomas non associated with myasthenia gravis. Nosologic aspects and therapeutic correlations]. | A series of nine tumors of the thymus gland without myasthenia is presented. Five neoplasms were benign, while four malignant in their biological behaviour and histology. The classification of these neoplasms was possible according to the embryology of the anterosuperior mediastinum and thymus as well as to the macrosc... | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myasthenia Gravis', 'Thymoma', 'Thymus Neoplasms'] | 2,733,847 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.614.550.500', 'C04.730.856.490', 'C10.114.656', 'C10.574.781.588', 'C10.668.758.725', 'C20.111.258.500'], ['C04.557.435.850', 'C04.588.894.949.500', 'C15.604.861.800'], ['C04.588.894.949', 'C15.604.861']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Activities of sordarins in murine histoplasmosis. | Sordarins are new antifungals which inhibit fungal protein synthesis by blocking elongation factor 2. Three compounds were evaluated in a murine model of histoplasmosis. Immune-competent mice were infected intravenously with 10(6) to 10(8) CFU of Histoplasma capsulatum yeast cells. Mice were treated either orally with ... | ['Amphotericin B', 'Animals', 'Antifungal Agents', 'Fluconazole', 'Histoplasma', 'Histoplasmosis', 'Indenes', 'Kidney', 'Lung', 'Male', 'Mice', 'Mice, Inbred ICR'] | 10,390,228 | [['D02.540.576.500.500'], ['B01.050'], ['D27.505.954.122.136'], ['D03.383.129.799.450'], ['B01.300.381.440'], ['C01.150.703.450'], ['D02.455.426.559.847.486', 'D04.615.486'], ['A05.810.453'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin transcriptionally down-regulates carboxylesterases through pregnane X receptor in an Akt-dependent manner. | Insulin is a major therapy for diabetes, and therefore, its role and mechanisms in the regulation of drug-metabolizing enzymes (DMEs), is of clinical importance to facilitate the rational drug use. Carboxylesterases are regarded as one of the major determinants of the metabolism and disposition of various substrates th... | ['Animals', 'Carboxylic Ester Hydrolases', 'Down-Regulation', 'Drug Interactions', 'HEK293 Cells', 'Hep G2 Cells', 'Hepatocytes', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Male', 'Mice, Inbred ICR', 'Pregnane X Receptor', 'Proto-Oncogene Proteins c-akt', 'Transcription, Genetic'] | 31,005,591 | [['B01.050'], ['D08.811.277.352.100'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G07.690.773.968'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.860.180.432', 'A11.436.348.500'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Precocious puberty: identifying early sexual development. | Primary care providers should have the ability to identify normal and abnormal variations of sexual development in children. The incidence of precocious puberty is approximately one child in every 10,000 children in the United States. While etiologies vary, precise differential diagnosis is essential because it will de... | ['Adolescent', 'Child', 'Counseling', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Nurse Practitioners', 'Nursing Assessment', 'Puberty, Precocious'] | 2,586,857 | [['M01.060.057'], ['M01.060.406'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.650.640', 'N02.360.650.640'], ['N04.590.233.508.480'], ['C19.391.693']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Imaging the ER and Endomembrane System in Cereal Endosperm. | The cereal endosperm is a complex structure comprising distinct cell types, characterized by specialized organelles for the accumulation of storage proteins. Protein trafficking in these cells is complicated by the presence of several different storage organelles including protein bodies (PBs) derived from the endoplas... | ['Biomarkers', 'Edible Grain', 'Endoplasmic Reticulum', 'Endosperm', 'Intracellular Membranes', 'Microscopy, Electron', 'Molecular Imaging', 'Plant Proteins'] | 29,043,684 | [['D23.101'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['A11.284.430.214.190.875.248'], ['A18.024.500.750.666'], ['A11.284.149.450', 'A11.284.835.514'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.350.557', '... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Involvement of NK1 and NK2 receptors in pulmonary responses elicited by non-adrenergic, non-cholinergic vagal stimulation in guinea-pigs. | Previous studies from our laboratory using exogenously administered neurokinin (NK) agonists have shown that both NK1- and NK2-receptor subtypes are involved in plasma extravasation in the guinea-pig airways. In the present study, we have extended these observations using antidromic vagal stimulation to stimulate senso... | ['Animals', 'Benzamides', 'Bronchi', 'Bronchoconstriction', 'Capillary Permeability', 'Enalapril', 'Guinea Pigs', 'Male', 'Piperidines', 'Receptors, Neurokinin-1', 'Receptors, Neurokinin-2', 'Substance P', 'Thiorphan', 'Trachea', 'Vagus Nerve'] | 8,708,985 | [['B01.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['A04.411.125'], ['G09.772.705.700.080'], ['G03.143.330', 'G09.330.165'], ['D12.644.456.345.360'], ['B01.050.150.900.649.313.992.550'], ['D03.383.621'], ['D12.776.543.750.695.862.500', 'D12.776.543.750.720.600.830.500', 'D12.776.543.75... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Traumatic Rupture of Posterior Tibial Tendon Following Closed Supination-Adduction Ankle Fracture: A Case Report. | CASE: A 25-year-old man with no known comorbidities presented with pain and swelling of the left ankle following a twisting injury that had occurred during a road traffic accident. On examination, a 1 ? 1-cm abrasion was noted on the medial malleolus and tenderness was noted over the medial and lateral malleoli. A radi... | ['Adult', 'Ankle Fractures', 'Humans', 'Male', 'Tendon Injuries'] | 29,252,652 | [['M01.060.116'], ['C26.404.014'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.874']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Thermodynamic entropy of organic oxidation in the water environment: experimental evaluation compared to semi-empirical calculation. | Residual organic matters in the secondary effluent are usually less biodegradable in terms of the total organic carbon content, and when discharged into a receiving water body, their further decomposition most likely mainly occurs due to chemical oxidation. Using this scenario, a semi-empirical method was previously de... | ['Entropy', 'Hydrophobic and Hydrophilic Interactions', 'Models, Theoretical', 'Organic Chemicals', 'Oxidation-Reduction', 'Thermodynamics', 'Water Pollutants, Chemical'] | 27,502,459 | [['G01.906.345'], ['G02.409'], ['E05.599'], ['D02'], ['G02.700', 'G03.295.531'], ['G01.906'], ['D27.888.284.903.655']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Second M3 | BACKGROUND AND PURPOSE: The bronchodilator tiotropium binds not only to its main binding site on the M3 muscarinic receptor but also to an allosteric site. Here, we have investigated the functional relevance of this allosteric binding and the potential contribution of this behaviour to interactions with long-acting â-a... | ['Acetylcholine', 'Adrenergic beta-2 Receptor Agonists', 'Animals', 'Binding Sites', 'Bronchodilator Agents', 'Cattle', 'Cholinergic Antagonists', 'Humans', 'In Vitro Techniques', 'Molecular Dynamics Simulation', 'Receptor, Muscarinic M3', 'Tiotropium Bromide', 'Trachea'] | 31,077,341 | [['D02.092.211.111'], ['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['B01.050'], ['G02.111.570.120'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['B01.050.150.900.649.313.500.380.271'], ['D27.505.519.625.120.200', 'D27.505.696.577.120.200'], ['B01.050.150.900.649.313.988.400.112.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Repair roles of hSMUG1 assessed by damage specificity and cellular activity. | Single-strand-selective monofunctional uracil-DNA glycosylase (SMUG1) was previously identified as a putative backup enzyme of major mammalian uracil-DNA glycosylase (UDG). However, the subsequent studies have shown conflicting results about the substrate specificity of SMUG1. In the present study, to clarify the repai... | ['DNA Glycosylases', 'DNA Repair', 'HeLa Cells', 'Humans', 'N-Glycosyl Hydrolases', 'Oxidative Stress', 'Uracil-DNA Glycosidase'] | 14,510,481 | [['D08.811.074.249', 'D08.811.277.450.430.099'], ['G02.111.222', 'G05.219'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.450.430'], ['G03.673', 'G07.775.750'], ['D08.811.074.249.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of a novel environment on alcohol-induced locomotor activity in Wistar rats. | Clinical studies have shown a positive correlation between novelty-seeking behavior and the susceptibility to consume drugs of abuse. Although several animal studies have demonstrated this correlation with psychostimulants or morphine, studies with alcohol have shown conflicting results. The aim of this work was to inv... | ['Animals', 'Blood Alcohol Content', 'Dose-Response Relationship, Drug', 'Ethanol', 'Exploratory Behavior', 'Male', 'Motor Activity', 'Rats', 'Rats, Wistar', 'Stereotyped Behavior'] | 29,929,089 | [['B01.050'], ['D02.033.375.135'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.375'], ['F01.145.387', 'F01.658.370'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['F01.145.896']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Football training improves cardiovascular health profile in sedentary, premenopausal hypertensive women. | The present study examined the effects of short-term recreational football training on blood pressure (BP), fat mass, and fitness in sedentary, 35-50-year-old premenopausal women with mild hypertension. Forty-one untrained, hypertensive women were randomized into a football training group (n = 21; FTG) and a control gr... | ['Adiposity', 'Adult', 'Biomarkers', 'Blood Pressure Determination', 'Cholesterol', 'Exercise Test', 'Exercise Therapy', 'Female', 'Humans', 'Hypertension', 'Middle Aged', 'Physical Fitness', 'Premenopause', 'Sedentary Behavior', 'Soccer', 'Treatment Outcome', 'Triglycerides'] | 24,944,131 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.116'], ['D23.101'], ['E01.370.370.140', 'E01.370.600.100'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E02.760.169... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Carbon flux to growth or polyhydroxyalkanoate synthesis under microaerophilic conditions is affected by fatty acid chain-length in Pseudomonas putida LS46. | Economical production of medium-chain length polyhydroxyalkanoates (mcl-PHA) is dependent on efficient cultivation processes. This work describes growth and mcl-PHA synthesis characteristics of Pseudomonas putida LS46 when grown on medium-chain length fatty acids (octanoic acid) and lower-cost long-chain fatty acids (L... | ['Bioreactors', 'Carbon', 'Fatty Acids', 'Industrial Microbiology', 'Polyhydroxyalkanoates', 'Pseudomonas putida'] | 29,799,090 | [['E07.115', 'J01.897.120.115'], ['D01.268.150'], ['D10.251'], ['H01.158.273.540.460', 'J01.897.120.460'], ['D05.750.078.789', 'D05.750.728.890', 'D10.751'], ['B03.440.400.425.625.625.675', 'B03.660.250.580.590.580']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparative effects of acebutolol and practolol on the lipolytic response to isoprenaline. | 1 The effects of beta-adrenoceptor blockade on the metabolic responses to isoprenaline have been studied in an in vitro system of isolated fat cells and in six normal subjects. 2 The inhibitory effects of varying concentrations of acebutolol, practolol and propranolol on free fatty acid (FFA) release produced by isopre... | ['Acebutolol', 'Adult', 'Animals', 'Blood Pressure', 'Fatty Acids, Nonesterified', 'Heart Rate', 'Humans', 'In Vitro Techniques', 'Isoproterenol', 'Lipid Metabolism', 'Male', 'Middle Aged', 'Placebos', 'Practolol', 'Propranolol', 'Rats'] | 973,938 | [['D02.033.100.624.698.025', 'D02.033.755.624.698.025', 'D02.092.063.624.698.025'], ['M01.060.116'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D10.251.310'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D02.033.100.291.439', 'D02.092.063.29... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hypothalamic-pituitary-adrenal axis and sympathetic nervous system activities in Pima Indians and Caucasians. | It has been proposed that both hypercortisolism and low sympathetic nervous system (SNS) activity contribute to obesity. Because glucocorticoids inhibit SNS activity, we hypothesized that hypercortisolism and low SNS activity may be found in association in Pima Indians, a population with a high prevalence of obesity. W... | ['Adrenocorticotropic Hormone', 'Adult', 'Catecholamines', 'Diabetes Mellitus', 'Diet', 'European Continental Ancestry Group', 'Hormones', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Indians, North American', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Obesity', 'Pituitary-Adrenal System', 'Sympathet... | 10,094,120 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['C18.452.394.750', 'C19.246'], ['G07.203.650.240'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
pdb-care (PDB carbohydrate residue check): a program to support annotation of complex carbohydrate structures in PDB files. | BACKGROUND: Carbohydrates are involved in a variety of fundamental biological processes and pathological situations. They therefore have a large pharmaceutical and diagnostic potential. Knowledge of the 3D structure of glycans is a prerequisite for a complete understanding of their biological functions. The largest sou... | ['Carbohydrate Conformation', 'Carbohydrate Sequence', 'Carbohydrates', 'Software'] | 15,180,909 | [['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['D09'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Neuromuscular excitability changes in the vastus medialis following anterior cruciate ligament reconstruction. | PURPOSE: Quadriceps weakness following anterior cruciate ligament reconstruction (ACLR) is prevalent despite intensive rehabilitation. Diminished neuromuscular excitability is one potential factor that may limit muscular recovery following injury or surgery. The H-reflex provides a measure of alpha motorneuron (neuromu... | ['Adult', 'Anterior Cruciate Ligament', 'Female', 'H-Reflex', 'Humans', 'Knee Joint', 'Male', 'Motor Neurons', 'Pain Measurement', 'Patellar Ligament', 'Postoperative Complications', 'Prospective Studies', 'Quadriceps Muscle', 'Reconstructive Surgical Procedures', 'Recovery of Function', 'Transplantation, Autologous', ... | 19,280,799 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['G11.561.731.643.474'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['A08.675.655.500', 'A11.671.655.500'], ['E01.370.600.550.324'], ['A02.513.514.475', 'A02.835.583.512.475', 'A02.880.438', 'A10.165.669.514.... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The right-hemisphere bias in conditional reasoning: a short report on multiple failures to replicate previous findings. | The present set of studies attempted to replicate Gellatly's (1985) findings that were supportive of Evan's (1982) hypothesis that the right hemisphere produces a selective bias towards the incorrect solution of a complex reasoning task. Subjects solved problems of the form "if p then q." In four studies, participants ... | ['Attention', 'Discrimination Learning', 'Dominance, Cerebral', 'Humans', 'Pattern Recognition, Visual', 'Problem Solving', 'Psychomotor Performance'] | 1,620,797 | [['F02.830.104.214'], ['F02.463.425.280'], ['F02.830.297', 'G11.561.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.425.725', 'F02.463.785.810'], ['F02.808', 'G11.427.700', 'G11.561.660']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
T cell development from kit-negative progenitors in the Foxn1Delta/Delta mutant thymus. | Foxn1Delta is a hypomorphic allele of the nude gene that causes arrested thymic epithelial cell differentiation and abnormal thymic architecture lacking cortical and medullary domains. T cells develop in the Foxn1Delta/Delta adult thymus to the double- and single-positive stages, but in the apparent absence of double-n... | ['Animals', 'B-Lymphocytes', 'Cell Differentiation', 'Forkhead Transcription Factors', 'Gene Deletion', 'Intracellular Signaling Peptides and Proteins', 'Killer Cells, Natural', 'Membrane Proteins', 'Mice', 'Mice, Mutant Strains', 'Mutation', 'Proto-Oncogene Proteins c-kit', 'Stem Cells', 'T-Lymphocytes', 'Thymus Gland... | 18,178,831 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.152'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.365.590.762.320', 'G05.558.800.320'], ['D12.644.360', 'D12.776.476'], ['A11.118.637.555.567.537', 'A15.145.229.637.555... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling the impacts of climate change and technical progress on the wheat yield in inland China: An autoregressive distributed lag approach. | This study aims to evaluate the impacts of climate change and technical progress on the wheat yield per unit area from 1970 to 2014 in Henan, the largest agricultural province in China, using an autoregressive distributed lag approach. The bounded F-test for cointegration among the model variables yielded evidence of a... | ['China', 'Climate Change', 'Triticum'] | 28,950,027 | [['Z01.252.474.164'], ['G16.500.175.374'], ['B01.650.940.800.575.912.250.822.918']] | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Clinical application of Web Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo): Patterns of blood sampling and patient characteristics among clinician users. | BACKGROUND: Use of population pharmacokinetics (PopPK) to facilitate PK-informed prophylaxis in clinical practice has gained momentum among haemophilia providers due to the accessibility of tools such as the Web Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) and availability of extended half-life... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Blood Specimen Collection', 'Child', 'Child, Preschool', 'Dose-Response Relationship, Drug', 'Factor VIII', 'Hemophilia A', 'Humans', 'Infant', 'Internet', 'Middle Aged', 'Physicians', 'Young Adult'] | 31,742,831 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['M01.060.406'], ['M01.060.406.448'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['C15.378.100.100.500', 'C15.378.100.141.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Treatment of chronic sternal fistulae following cardiac surgery with a bone substitute. | Chronic sternal infection is a relatively rare complication following cardiac surgery that can cause high morbidity and mortality and can require repeated surgical procedures, including sternal resection, to resolve. However, preserving sternal integrity is essential, particularly in children. A variety of conservative... | ['Biocompatible Materials', 'Bone Substitutes', 'Calcium Phosphates', 'Cardiac Surgical Procedures', 'Child', 'Chronic Disease', 'Durapatite', 'Female', 'Fistula', 'Humans', 'Infection Control', 'Male', 'Sternotomy', 'Sternum', 'Surgical Wound Infection', 'Wound Healing'] | 24,049,817 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D25.130.325', 'J01.637.051.130.325'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['C23.550.291.500'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Challenges in the clinical diagnosis of Alzheimer's disease: influence of "family coaching" on the mini-mental state examination. | The Mini-Mental State Examination (MMSE) is a commonly used clinical tool for evaluating the cognitive aspects of mental function. In this study, 40 consecutive patients presenting to a memory disorder clinic and their caregivers were evaluated for coaching of the patient with respect to MMSE content over the 24 hours ... | ['Aged', 'Alzheimer Disease', 'Caregivers', 'Female', 'Humans', 'Male', 'Motivation', 'Neuropsychological Tests', 'Teaching'] | 16,634,466 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['F04.711.513'], ['I02.903']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Fusion expression of SLT-IIeB gene and FedF gene of Ee in Escherichia coli and its immunogenicity]. | The DNA fragment encoding the truncated SLT-IIeB and FedF of Ee strain were fused to the downstream of glutathione S-transferase (GST) of pGEX-KG expression vector, resulting in the fusion expression plasmid pKSF. After transformed into E. coli BL21 (DE3) and induced by IPTG, the results of SDS-PAGE showed that the GST... | ['Adhesins, Bacterial', 'Animals', 'Chlorocebus aethiops', 'Escherichia coli', 'Escherichia coli Proteins', 'Female', 'Mice', 'Mutation', 'Plasmids', 'Recombinant Fusion Proteins', 'Shiga Toxins', 'Vero Cells'] | 18,271,261 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.590'], ['G05.360.600'], ['D12.776.828.300'], ['D08... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of oral appliance therapy on blood pressure in Japanese patients with obstructive sleep apnea. | OBJECTIVE: Obstructive sleep apnea (OSA) treatment in patients with OSA and hypertension reduces blood pressure (BP). Oral appliance (OA) therapy is nowadays prescribed for patients with mild to moderate OSA. This study aimed to clarify the effect of OA therapy on BP reduction in Japanese patients with mild to moderate... | ['Adult', 'Aged', 'Blood Pressure', 'Blood Pressure Determination', 'Female', 'Humans', 'Hypertension', 'Japan', 'Male', 'Middle Aged', 'Polysomnography', 'Respiratory Therapy', 'Sleep Apnea, Obstructive', 'Treatment Outcome'] | 27,158,750 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['E01.370.520.625'], ['E02.880'], ['C08.618.085.852.850', 'C10.886.425.800... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The effects of anesthesia on otoacoustic emissions. | We have measured transient-evoked and distortion-product otoacoustic emissions (OAEs) in the chinchilla and compared them in the awake and anesthetized animal (using either ketamine or barbiturate agents). We report a significant increase in OAE amplitudes during anesthesia, particularly using ketamine. These effects a... | ['Acoustic Stimulation', 'Adjuvants, Anesthesia', 'Anesthesia, General', 'Anesthetics, Dissociative', 'Animals', 'Atropine', 'Barbiturates', 'Chinchilla', 'Cochlea', 'Evoked Potentials, Auditory, Brain Stem', 'Ketamine', 'Neurons, Efferent', 'Otoacoustic Emissions, Spontaneous', 'Sodium Chloride'] | 9,282,886 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['D27.505.954.427.010'], ['E03.155.197'], ['D27.505.696.277.100.035.075.035', 'D27.505.954.427.210.100.035.075.035'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nodular histiocytic aggregates in the endometrium: a report of 7 cases. | Nodular aggregates of nonfoamy histiocytes in the endometrium are uncommon. We describe herein the clinical and pathologic characteristics of 7 additional cases in endometrial biopsies or curettages. The patients ranged in age from 48 to 72 years, and the most common presenting symptom was abnormal uterine bleeding. Fi... | ['Aged', 'Endometrium', 'Female', 'Histiocytes', 'Humans', 'Middle Aged', 'Uterine Diseases'] | 24,300,536 | [['M01.060.116.100'], ['A05.360.319.679.490'], ['A11.329.372.385', 'A11.627.482.385', 'A11.733.397.385', 'A15.382.670.522.385', 'A15.382.680.397.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C13.351.500.852']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A cost-effectiveness comparison of embryo donation with oocyte donation. | OBJECTIVE: To compare the cost-effectiveness of embryo donation (ED) to that of oocyte donation (OD).DESIGN: Calculation of cost-effectiveness ratios (costs per outcome achieved) using data derived from clinical practices.SETTING: In vitro fertilization centers and embryo donation programs.PATIENT(S): Infertile couples... | ['Cost-Benefit Analysis', 'Costs and Cost Analysis', 'Delivery, Obstetric', 'Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Humans', 'Infant, Newborn', 'Infertility, Female', 'Oocyte Donation', 'Pregnancy', 'Reproductive Techniques, Assisted', 'United States'] | 19,406,398 | [['N03.219.151.125'], ['N03.219.151'], ['E04.520.252'], ['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C13.351.500.365.700'], ['E02.875.800.968', 'E05.820.800.968'], ['G08.686.784.769'], ['E02.875.800', 'E05.820.800... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
alpha-Adrenolytic treatment in patients with autonomous bladders. | The effect of alpha-adrenolytic treatment (phenoxybenzamine) was studied in 8 patients with lower motor neuron lesions (autonomous bladders). In the cystometrograms, the bladders were more hypotonic and the "autononous waves" appeared at a higher level of filling or were totally extinguished after this pharmacological ... | ['Adult', 'Clinical Trials as Topic', 'Drug Evaluation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Phenoxybenzamine', 'Pressure', 'Urethra', 'Urinary Bladder', 'Urinary Bladder, Neurogenic', 'Urination', 'Urodynamics'] | 362,818 | [['M01.060.116'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.092.471.739'], ['G01.374.715'], ['A05.360.444.492.726', 'A05.810.876'], ['A05.810.890'], ['C10.597.900', 'C12.777.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nanoimprinted thin films of reactive, azlactone-containing polymers: combining methods for the topographic patterning of cell substrates with opportunities for facile post-fabrication chemical functionalization. | Approaches to the fabrication of surfaces that combine methods for the topographic patterning of soft materials with opportunities for facile, post-fabrication chemical functionalization could contribute significantly to advances in biotechnology and a broad range of other areas. Here, we report methods that can be use... | ['Animals', 'Cell Adhesion', 'Cell Proliferation', 'Lactones', 'Methacrylates', 'Mice', 'Molecular Imprinting', 'NIH 3T3 Cells', 'Nanotechnology', 'Polyethylene Glycols', 'Polymers', 'Silicon', 'Surface Properties'] | 19,290,643 | [['B01.050'], ['G04.022'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.540'], ['D02.241.081.069.600'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.196.655', 'E05.197.453', 'J01.897.836.249.437'], ['A11.251.210.100.550', 'A11.329.228.100.550'], ['H01.603', 'J01.897.520.600'], ['D02.033.455.250.700', 'D05.750.74... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Biological and biochemical anti-HIV activity of the benzothiadiazine class of nonnucleoside reverse transcriptase inhibitors. | A series of benzothiadiazine derivatives were screened against the human immunodeficiency virus (HIV) and certain structure-activity relationships were defined for anti-HIV activity in this chemical class. The selected representative NSC 287474 was a highly potent inhibitor of HIV-induced cell killing and HIV replicati... | ['Antiviral Agents', 'Base Sequence', 'Benzothiadiazines', 'Cell Line', 'Cells, Cultured', 'Drug Evaluation, Preclinical', 'Drug Resistance, Microbial', 'Drug Synergism', 'HIV Reverse Transcriptase', 'HIV-1', 'HIV-2', 'Humans', 'Molecular Sequence Data', 'Reverse Transcriptase Inhibitors', 'Structure-Activity Relations... | 7,529,014 | [['D27.505.954.122.388'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.886.590.700.135', 'D02.886.655.500', 'D03.633.100.174'], ['A11.251.210'], ['A11.251'], ['E05.290.750', 'E05.337.550'], ['G06.225', 'G07.690.773.984.269'], ['G07.690.773.968.477'], ['D08.811.913.696.445.308.300.750.187', 'D12.776.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mediterranean Dietary Pattern is Associated with Low Risk of Aggressive Prostate Cancer: MCC-Spain Study. | PURPOSE: We explored the association of the previously described Western, prudent and Mediterranean dietary patterns with prostate cancer risk by tumor aggressiveness and extension.MATERIALS AND METHODS: MCC-Spain (Multicase-Control Study on Common Tumors in Spain) is a population based, multicase-control study that wa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Diet Surveys', 'Diet, Mediterranean', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Prostatic Neoplasms', 'Protective Factors', 'Risk Factors', 'Spain'] | 28,842,246 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.308.980.485.350', 'N05.715.360.300.800.469.300', 'N06.850.505.616.300', 'N06.850.520.308.980.469.350'], ['E02.642.249.270', 'G07.203.650.240.270'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The epidermal growth factor-like domain from tissue plasminogen activator. Cloning in E. coli, purification and ESR studies of its interaction with human blood platelets. | To examine whether the epidermal growth factor (EGF)-like domain Pro47-Asp87 is involved in the interaction of tissue plasminogen activator (t-PA) with platelets, we have expressed this domain in E. coli. The peptide fragment was produced from a plasmid expression vector as a fusion protein with beta-galactosidase Met1... | ['Base Sequence', 'Blood Platelets', 'Cloning, Molecular', 'Electron Spin Resonance Spectroscopy', 'Epidermal Growth Factor', 'Escherichia coli', 'Humans', 'Molecular Sequence Data', 'Peptide Fragments', 'Protein Binding', 'Protein Structure, Tertiary', 'Recombinant Proteins', 'Tissue Plasminogen Activator'] | 8,030,371 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.118.188', 'A15.145.229.188'], ['E05.393.220'], ['E05.196.867.519.274'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The antral gastrin-producing cells in duodenal ulcer patients. An ultrastructural study before and during treatment with cimetidine. | Ultrastructural examination of the antral G cells has been carried out on 11 patients with chronic duodenal ulcer, before and after treatment with a histamine H-2 - receptor antagonist (cimetidine 1 g/day) for 8 weeks. The study demonstrated an increased area of the Golgi complex, rough endoplasmic reticulum and electr... | ['Adult', 'Cimetidine', 'Duodenal Ulcer', 'Endocrine Glands', 'Female', 'Gastrins', 'Golgi Apparatus', 'Humans', 'Male', 'Middle Aged', 'Pyloric Antrum'] | 3,923,703 | [['M01.060.116'], ['D02.078.370.200', 'D03.383.129.308.130'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['A06.300'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D12.776.631.650.320'], ['A11.284.430.214.190.875.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Federal environmental and occupational toxicology regulations and reporting requirements: a practical approach to what the medical toxicologist needs to know, part 1. | Toxicologists are often called upon to assist in environmental, industrial, occupational and public health assessments. Accordingly, medical toxicologists may find it prudent to be aware of applicable federal toxicological regulations and reporting requirements and of the roles of relevant federal agencies. These regul... | ['Ecotoxicology', 'Government Agencies', 'Hazardous Waste', 'Humans', 'Occupational Health', 'Toxicology', 'United States', 'United States Environmental Protection Agency'] | 25,023,223 | [['H01.158.273.248.500', 'H01.158.891.211', 'H01.277.249.500', 'H02.884.211'], ['I01.409.418', 'N03.540.400'], ['D20.944.380', 'D27.888.426.500', 'N06.850.460.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.400.525'], ['H01.158.891', 'H02.884'], ['Z01.107.567.875'], ['I01.409.418.750.937', 'N03.540.34... | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Inhibition of 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) activities of human placenta by steroids and non-steroidal hormone agonists and antagonists. | Various naturally occurring steroids, synthetic steroid derivatives and non-steroidal hormone agonists and antagonists were assayed as inhibitors of human placental 17 beta-HSD activities. Microsomal 17 beta-HSD was inhibited by C18-, C19- and C21-steroids. Soluble 17 beta-HSD was highly specific for C18-steroids. In c... | ['17-Hydroxysteroid Dehydrogenases', 'Female', 'Hormone Antagonists', 'Hormones', 'Humans', 'In Vitro Techniques', 'Microsomes', 'Placenta', 'Pregnancy', 'Steroids'] | 6,597,979 | [['D08.811.682.047.436.375'], ['D06.347', 'D27.505.696.399.450'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A11.284.835.540'], ['A16.710'], ['G08.686.784.769'], ['D04.210.500']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inclusion of Dap10 or 4-1BB costimulation domains in the chPD1 receptor enhances anti-tumor efficacy of T cells in murine models of lymphoma and melanoma. | Chimeric antigen receptors (CAR) utilize costimulatory domains to enhance anti-tumor efficacy. However, it is unclear which costimulatory domain is preferable. Therefore, the intracellular domains of CD28, Dap10, 41BB, GITR, ICOS, or OX40 were compared in a murine chimeric PD1 (chPD1) receptor that targets tumor-associ... | ['4-1BB Ligand', 'Animals', 'Disease Models, Animal', 'Female', 'Immunotherapy, Adoptive', 'Lymphoma', 'Male', 'Melanoma, Experimental', 'Mice', 'Mice, Inbred C57BL', 'Programmed Cell Death 1 Receptor', 'Receptors, Antigen, T-Cell', 'Receptors, Chimeric Antigen', 'Receptors, Immunologic'] | 32,106,933 | [['D12.644.276.374.750.065', 'D12.776.395.192', 'D12.776.467.374.750.065', 'D12.776.543.550.194', 'D23.529.374.750.065'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.095.465.425.400.330.050.400', 'E05.478.550.520.050.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['C04.557.465.625.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Osteoid-osteoma as a cause of scoliosis. | In nine cases of osteoid-osteoma causing scoliosis, all lesions were in the spine and several led to significant structural spine changes. One patient had two distinct spine lesions two years apart. Almost all cases were misdiagnosed and improperly treated at first. Prompt recognition should lead to early surgical exci... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Humans', 'Laminectomy', 'Male', 'Osteoma, Osteoid', 'Scoliosis', 'Spinal Fusion', 'Spinal Neoplasms'] | 1,112,842 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['C04.557.450.565.575.625.625'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of Pneumocystis carinii in respiratory specimens by PCR-solution hybridization enzyme-linked immunoassay. | By using a recently developed PCR-solution hybridization enzyme-linked assay (PCR-SHELA), we investigated Pneumocystis carinii in bronchoalveolar lavage fluid samples and induced sputa of patients with pneumocystosis. In detecting P. carinii, PCR-SHELA proved more sensitive than immunofluorescence staining or a single ... | ['AIDS-Related Opportunistic Infections', 'Adult', 'Bronchoalveolar Lavage Fluid', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nucleic Acid Hybridization', 'Pneumocystis', 'Pneumonia, Pneumocystis', 'Polymerase Chain Reaction', 'Predictive Value of Tests', 'Sensitivity and Specifici... | 9,163,489 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['M01.060.116'], ['E05.927.100.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.11... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Experiences of the first 16 hospitals using copper-silver ionization for Legionella control: implications for the evaluation of other disinfection modalities. | BACKGROUND AND OBJECTIVES: Hospital-acquired legionnaires' disease can be prevented by disinfection of hospital water systems. This study assessed the long-term efficacy of copper-silver ionization as a disinfection method in controlling Legionella in hospital water systems and reducing the incidence of hospital-acquir... | ['Centers for Disease Control and Prevention, U.S.', 'Copper', 'Cross Infection', 'Disinfection', 'Environmental Monitoring', 'Evaluation Studies as Topic', 'Evidence-Based Medicine', 'Humans', "Legionnaires' Disease", 'Maintenance and Engineering, Hospital', 'Silver', 'United States', 'Water Microbiology', 'Water Puri... | 12,940,575 | [['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['C01.248', 'C23.550.291.875.500'], ['N06.850.780.200.450.850.375'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.337', 'N05.715.360.335'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.1... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
New insights into the evolution of intronic sequences of the beta-fibrinogen gene and their application in reconstructing mustelid phylogeny. | Mustelidae is the largest and most diverse family in the order Carnivora. The phylogenetic relationships among the subfamilies have especially long been a focus of study. Herein we are among the first to employ two new introns (4 and 7) of the nuclear beta-fibrinogen gene to clarify these enigmatic problems. In additio... | ['Animals', 'Base Sequence', 'Bayes Theorem', 'Evolution, Molecular', 'Fibrinogen', 'Introns', 'Likelihood Functions', 'Models, Genetic', 'Molecular Sequence Data', 'Mustelidae', 'Phylogeny', 'Sequence Analysis, DNA', 'Short Interspersed Nucleotide Elements'] | 18,624,576 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G05.045.250', 'G16.075.250'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Sodium houttuyfonate inhibits inflammation by blocking the MAPKs/NF-êB signaling pathways in bovine endometrial epithelial cells. | Sodium houttuyfonate (SH) has traditionally been used for the therapy of inflammatory diseases. In this research, we tried to assess the anti-inflammatory effects of SH on LPS-induced bovine endometrial epithelial cell (bEEC) inflammation. SH cell toxicity was measured using the MTT and LDH assays, and inflammatory cyt... | ['Alkanes', 'Animals', 'Anti-Inflammatory Agents', 'Cattle', 'Cattle Diseases', 'Chemokines', 'Cytokines', 'Endometritis', 'Endometrium', 'Epithelial Cells', 'Female', 'Inflammation', 'MAP Kinase Signaling System', 'NF-kappa B', 'Signal Transduction', 'Sulfites'] | 25,935,757 | [['D02.455.326.146'], ['B01.050'], ['D27.505.954.158'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C13.351.500.056.750.249', 'C13.351.500.852.299'], ['A05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Indices of the functional and secretory activity of EC cells of the stomach of the rat after electric stimulation of the vagus nerve]. | Within 1, 5, 10 and 30 min after a direct short-term electrical stimulation of the vagus nerve, the amount of histochemically detectable EC-cells was counted and dynamics of changes in stereometric characteristics of their subcellular organelles were investigated in the antral part of the mucous membrane of the rat sto... | ['Animals', 'Cell Differentiation', 'Chromaffin System', 'Cytoplasmic Granules', 'Electric Stimulation', 'Enterochromaffin Cells', 'Male', 'Mitosis', 'Rats', 'Serotonin', 'Stomach', 'Vagus Nerve'] | 3,781,041 | [['B01.050'], ['G04.152'], ['A06.224'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['E05.723.402'], ['A03.556.875.875.440.250', 'A06.224.358', 'A06.390.021', 'A10.615.550.291.162', 'A11.382.625.031', 'A11.436.294.031', 'A15.382.250'], ['G04.144.220.220.781', 'G05.113.220.781'], ['B01.050.150.900.64... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain-derived neurotrophic factor levels influence the balance of migration and differentiation of subventricular zone cells, but not guidance to the olfactory bulb. | New progenitor cells in the subventricular zone (SVZ) migrate rostrally and differentiate into interneurons in the olfactory bulb (OB) throughout life. Brain-derived neurotrophic factor (BDNF) may influence the normal progression of this migration. In the present study, mouse SVZ explant cultures were used to investiga... | ['Animals', 'Brain-Derived Neurotrophic Factor', 'Cell Differentiation', 'Cell Movement', 'Cells, Cultured', 'Mice', 'Mice, Inbred BALB C', 'Neural Stem Cells', 'Neurogenesis', 'Olfactory Bulb'] | 21,177,109 | [['B01.050'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['A11.872.653'], ['G04.152.91... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Five-year follow-up of regenerative periodontal therapy with enamel matrix derivative at sites with angular bone defects. | BACKGROUND: This prospective case series report aimed at analyzing the long-term (5 years) stability of clinical attachment level (CAL) gains following regenerative therapy with the use of enamel matrix proteins in intrabony defects.METHODS: A total of 114 consecutively treated periodontal patients (mean age: 55.8 year... | ['Adolescent', 'Adult', 'Aged', 'Alveolar Bone Loss', 'Alveolar Process', 'Dental Enamel Proteins', 'Dental Scaling', 'Female', 'Follow-Up Studies', 'Furcation Defects', 'Gingival Recession', 'Guided Tissue Regeneration, Periodontal', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Periodontal Attachment Loss... | 16,460,257 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C05.116.264.150', 'C07.465.714.354.500'], ['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['D12.776.231'], ['E06.721.189.350', 'E06.761.227.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], [... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PromPDD, a web-based tool for the prediction, deciphering and design of promiscuous peptides that bind to HLA class I molecules. | Promiscuous peptides that can be presented by multiple human leukocyte antigens (HLAs) have great potential for the development of vaccines with wide population coverage. However, the current available methods for the prediction of peptides that bind to major histocompatibility complex (MHC) are mainly aimed at the rap... | ['Algorithms', 'Computational Biology', 'Computer Simulation', 'Datasets as Topic', 'Histocompatibility Antigens Class I', 'Humans', 'Internet', 'Models, Chemical', 'Peptides', 'Protein Binding'] | 31,678,214 | [['G17.035', 'L01.224.050'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['E05.318.308.056', 'L01.313.500.750.300.188.400.500', 'L01.399.250.224', 'L01.470.750.750.431', 'N05.715.360.300.224', 'N06.850.520.308.056'], ['D12.776.395.550.489', 'D12.776.543.550.439', 'D23.050.301.500.100', 'D23.050.705.552.100'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
A 12-lead ECG-method for quantifying ischemia-induced QRS prolongation to estimate the severity of the acute myocardial event. | INTRODUCTION: Studies have shown terminal QRS distortion and resultant QRS prolongation during ischemia to be a sign of low cardiac protection and thus a faster rate of myocardial cell death. A recent study introduced a single lead method to quantify the severity of ischemia by estimating QRS prolongation. This paper i... | ['Acute Disease', 'Algorithms', 'Coronary Stenosis', 'Diagnosis, Computer-Assisted', 'Electrocardiography', 'Humans', 'Myocardial Ischemia', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Severity of Illness Index'] | 26,931,515 | [['C23.550.291.125'], ['G17.035', 'L01.224.050'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647', 'C14.907.585'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685',... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[MR image analysis of 147 cases of meningeal tuberculosis]. | OBJECTIVE: To investigate the MRI features of meningeal tuberculosis.METHODS: The MR images of meningeal tuberculosis were retrospectively analyzed in 147 patients who were clinically diagnosed from 2009 to 2014 years in our hospital, including 77 males, and 70 females. Their age ranged from 14 to 70 years, and the ave... | ['Adolescent', 'Adult', 'Aged', 'Brain', 'Contrast Media', 'Female', 'Humans', 'Lung Neoplasms', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Retrospective Studies', 'Tuberculosis, Meningeal', 'Young Adult'] | 26,850,769 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.7... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of the addisonian autoantigen in human adrenal tumors. | Sera of patients with Addison's disease contain autoantibodies recognizing antigen(s) in the adrenal cortex. In the present study we have examined the antigen expression in normal (n = 6) and pathological human adrenal tissues (n = 24) and also in the human steroid-producing adrenocortical cell line NCI-H295. Sera from... | ['Addison Disease', 'Adrenal Cortex', 'Adrenal Cortex Neoplasms', 'Adult', 'Aged', 'Autoantibodies', 'Autoantigens', 'Blotting, Western', 'Female', 'Fluorescent Antibody Technique', 'Humans', 'Male', 'Middle Aged', 'Tumor Cells, Cultured'] | 8,003,612 | [['C19.053.500.263', 'C20.111.163'], ['A06.300.071.140'], ['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['E05.196.401.143', 'E05.301.3... | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies. | Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL). The aim of our study was to investigate whether the routinely administered ALL chemotherapeutic agents would be able to bind and inhibit the key de... | ['Antineoplastic Agents', 'Arabinonucleosides', 'Carcinogenesis', 'Catalytic Domain', 'Cell Cycle Checkpoints', 'Cell Cycle Proteins', 'Curcumin', 'Daunorubicin', 'Doxorubicin', 'Humans', 'Hydrogen Bonding', 'Molecular Docking Simulation', 'Molecular Targeted Therapy', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma'] | 24,454,966 | [['D27.505.954.248'], ['D13.570.065'], ['C04.697.098', 'C23.550.727.098'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['G04.144.109'], ['D12.776.167'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.426.559.694.222'], ['D02.455.426.559.847.562.050.200', 'D04.615.562.050.200... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Non-specific nasal provocation in children with chronic allergic rhinitis. | Twenty-three children with chronic allergic rhinitis (Group A) and eleven normal non-atopic subjects (group C) were submitted to non-specific nasal provocation tests with histamine (0.03; 0.06; 0.125; 0.25; 0.5; 1.0; 2.0 and 4.0 mg/ml), and one week later with methacholine (0.025; 0.1; 0.25, 0.5; 1.0; 2.5; 5.0 and 10.0... | ['Adolescent', 'Child', 'Chronic Disease', 'Female', 'Histamine', 'Humans', 'Male', 'Methacholine Chloride', 'Nasal Provocation Tests', 'Respiratory Function Tests', 'Rhinitis, Allergic, Perennial', 'Rhinitis, Allergic, Seasonal'] | 8,727,268 | [['M01.060.057'], ['M01.060.406'], ['C23.550.291.500'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.877.883.555.500', 'D02.675.276.534.500'], ['E01.370.386.550'], ['E01.370.386.700'], ['C08.460.799.315.500', 'C08.674.45... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in renal function during physical and mental effort. | Aim of the study was to evaluate the renal responses to physical and mental effort in essential hypertension by means of a non-invasive radioisotopic method. Renal uptake rate of Tc99m-DMSA was evaluated in 10 subjects. Starting from 5 to 15 minutes after dose injection counts over the kidney region were acquired by me... | ['Humans', 'Hypertension', 'Kidney', 'Organometallic Compounds', 'Physical Exertion', 'Renal Circulation', 'Rest', 'Succimer', 'Technetium Tc 99m Dimercaptosuccinic Acid', 'Thinking'] | 2,824,100 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['A05.810.453'], ['D02.691'], ['G11.427.683'], ['G08.852.725', 'G09.330.100.812'], ['I03.450.769.647'], ['D02.241.081.337.759.500', 'D02.886.489.750'], ['D02.241.081.337.759.500.725', 'D02.691.825.468', 'D02.886.489.750.725'], ['F02.463.785']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Leg edema formation and venous blood flow velocity during a simulated long-haul flight. | INTRODUCTION: Long-distance traveling in a sitting position may be associated with an increased incidence for venous thromboembolism. As major contributing factors immobility and compression of leg veins are discussed. At present no studies have been performed measuring the time course of lower limb blood flow, leg vol... | ['Aircraft', 'Blood Flow Velocity', 'Body Composition', 'Body Temperature', 'Body Weight', 'Edema', 'Humans', 'Leg', 'Plethysmography', 'Posture', 'Thromboembolism', 'Time Factors', 'Travel', 'Venous Thrombosis'] | 17,250,877 | [['J01.937.285.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.875.374', 'G07.110'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C23.888.277'], ['B01.050.150.900.649.313.988.400.112.400... | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
The effect of early intervention and pre-school stimulus on the development of the Down's syndrome child. | This paper describes the effect on a group of D.S. children of early and continuous parental counselling together with intensive pre-school stimulation in which the parents were fully involved. The stimulated group is compared with a similar group who developed unaided in their own homes, and with a third group who wer... | ['Child Development', 'Child Rearing', 'Child, Preschool', 'Down Syndrome', 'Education of Intellectually Disabled', 'Humans', 'Intelligence', 'Intelligence Tests', 'Language Development', 'Social Class', 'Socialization'] | 158,093 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beyond the Levant: first evidence of a pre-pottery Neolithic incursion into the Nefud Desert, Saudi Arabia. | Pre-Pottery Neolithic assemblages are best known from the fertile areas of the Mediterranean Levant. The archaeological site of Jebel Qattar 101 (JQ-101), at Jubbah in the southern part of the Nefud Desert of northern Saudi Arabia, contains a large collection of stone tools, adjacent to an Early Holocene palaeolake. Th... | ['Archaeology', 'Civilization', 'Environment', 'Humans', 'Saudi Arabia'] | 23,894,294 | [['I01.076.201.208'], ['I01.076.201.450.226'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.750']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Seasonal variation of potential flavivirus vectors in an urban biological reserve in northeastern Brazil. | Although yellow fever (YF) has not been reported on the eastern coast of Brazil since 1942, there was a reemergence of dengue fever in Brazil in 1987 due to the reintroduction of Aedes aegypti (L.). To assess areas of potential risk for transmission of vector-borne diseases, a surveillance system was placed in a large ... | ['Animals', 'Brazil', 'Conservation of Natural Resources', 'Culicidae', 'Flavivirus', 'Insect Vectors', 'Larva', 'Population Density', 'Population Dynamics', 'Rain', 'Seasons', 'Temperature'] | 19,960,696 | [['B01.050'], ['Z01.107.757.176'], ['J01.256', 'N06.230.080'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['B04.820.578.344.350'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['N01.224.600', 'N06.850.505.400.600'], ['I01.240.600', 'N01.224.625', 'N06... | ['Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Trypanosoma cruzi: inhibition of host cell uptake of infective bloodstream forms by alpha-2-macroglobulin. | The infection of murine macrophages and fibroblasts by recently isolated infective bloodstream trypomastigotes of Trypanosoma cruzi is inhibited by the addition of human plasma protease inhibitor alpha-2-macroglobulin (alpha 2M) or of soybean trypsin inhibitor. The ingestion of the non-infective epimastigotes by macrop... | ['Animals', 'Cells, Cultured', 'Chagas Disease', 'Endocytosis', 'Fibroblasts', 'Macrophages', 'Temperature', 'Trypanosoma cruzi', 'alpha-Macroglobulins'] | 2,424,187 | [['B01.050'], ['A11.251'], ['C01.610.752.300.900.200', 'C01.920.625'], ['G04.417'], ['A11.329.228'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['B01.268.475.868.887... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Accuracy of fetal pulse oximetry. | BACKGROUND: The goal of this investigation was to evaluate the agreement of fetal pulse oximetry to saturation readings from hemoximetry at low oxygen saturation.METHODS: Fetal oxygen saturation measurements obtained by pulse oximetry were compared with those obtained by hemoximetry in fetal scalp blood samplings. The ... | ['Adult', 'Blood Gas Analysis', 'Female', 'Fetal Blood', 'Fetal Monitoring', 'Humans', 'Infant, Newborn', 'Oximetry', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Outcome', 'Prospective Studies'] | 12,027,815 | [['M01.060.116'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['E01.370.378.230', 'E01.370.520.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.38... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extracorporeal shock wave lithotripsy with a transportable electrohydraulic lithotripter: experience with >300 patients. | OBJECTIVE: To review a multicentre experience of using a transportable lithotripter (STS-T, Medstone, Inc, Aliso Viejo, CA. USA) for treating patients with urolithiasis in all parts of the urinary tract.PATIENTS AND METHODS: In all, 326 patients with a total of 370 stones were treated as outpatients with the STS-T lith... | ['Adult', 'Aged', 'Database Management Systems', 'Databases, Factual', 'Female', 'Follow-Up Studies', 'Humans', 'Kidney Calculi', 'Lithotripsy', 'Male', 'Middle Aged', 'Pain, Postoperative', 'Retrospective Studies', 'Treatment Outcome', 'Ureteral Calculi', 'Urinary Calculi', 'Urination Disorders'] | 16,104,918 | [['M01.060.116'], ['M01.060.116.100'], ['L01.224.068', 'L01.224.900.280', 'N04.452.515.110'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.9... | ['Named Groups [M]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Urinary monitoring of saccharin and acesulfame-K as biomarkers of exposure to these additives. | A method was developed to determine the levels of two intense sweeteners, saccharin and acesulfame-K, in human urine. Measurement of these two analytes in urine allowed an assessment to be made of dietary exposure to the sweeteners using intake/excretion curves. This paper describes an intake/excretion study in which 2... | ['Adolescent', 'Adult', 'Aged', 'Biomarkers', 'Child', 'Diet', 'Diet Records', 'Female', 'Humans', 'Male', 'Middle Aged', 'Saccharin', 'Sweetening Agents', 'Thiazines'] | 10,560,576 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['M01.060.406'], ['G07.203.650.240'], ['N04.452.859.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.886.675.687', 'D03.383.129.708.089.708', 'D03.633.100.185.708'], ['D27.720.372.300.353.609', 'G07.203.300.514.500.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Changes in phospholipid composition in rat liver microsomes and mitochondria under chemical carcinogenesis]. | Considerable change in phospholipid composition of microsomal and mitochondrial rat liver membranes under 3,4-benzpyrene-induced cancerogenesis is observed. The content of main phospholipid fractions (phosphatidylethanolamines and phosphatidylcholines) in rat liver microsomes increases at precancer stage and decreases ... | ['Animals', 'Benzopyrenes', 'Liver Neoplasms', 'Microsomes, Liver', 'Mitochondria, Liver', 'Neoplasms, Experimental', 'Phosphatidylcholines', 'Phosphatidylethanolamines', 'Phospholipids', 'Precancerous Conditions', 'Rats', 'Sphingomyelins'] | 889,961 | [['B01.050'], ['D02.455.426.559.847.799.306', 'D04.615.799.306'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['A11.284.835.540.541'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['C04.619', 'E05.598.500.496'], ['D10.570.755.375.760.400.800'], ['D10.570.755.375.760.400.840'], ['D10.570.755'], ['C... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of a multi-modality life support system. | The purpose of this study was to describe the design and utilization of a multi-modality life support system (MMLSS), which is used to provide extracorporeal support for cases such as left heart bypass (LHB), extracorporeal life support (ECLS), veno-venous bypass, and hypothermic resuscitation. The design of the MMLSS ... | ['Cardiopulmonary Bypass', 'Combined Modality Therapy', 'Equipment Design', 'Extracorporeal Circulation', 'Heart Bypass, Left', 'Humans', 'Hypothermia, Induced'] | 19,192,756 | [['E04.292.413'], ['E02.186'], ['E05.320'], ['E04.292'], ['E04.292.465'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A case of pelvic paragonimiasis combined with myoma uteri and pelvic inflammatory disease]. | Paragonimus westermani is a lung fluke of humans that is usually found in the lungs but may be found elsewhere in many unusual locations. A case of pelvic paragonimiasis was found incidentally by surgical intervention of inflammatory disease and myoma uteri. She was a 51-year-old Korean woman complaining of lower abdom... | ['Female', 'Humans', 'Hysterectomy', 'Leiomyoma', 'Middle Aged', 'Paragonimiasis', 'Pelvic Inflammatory Disease', 'Uterine Neoplasms'] | 8,241,090 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['C04.557.450.590.450'], ['M01.060.116.630'], ['C01.610.335.865.741'], ['C01.635.500', 'C13.351.500.056.750'], ['C04.588.945.418.948', 'C13.351.500.852.762', 'C13.351.937.418.875']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of cyanide on the efflux of calcium from squid axons. | 1. The average rate constant for loss of (45)Ca from an unpoisoned squid axon was 1.8 x 10(-3) min(-1), corresponding to an efflux of 0.2 p-mole/cm(2) sec.2. The Ca efflux from unpoisoned axons was reduced if external calcium was replaced with magnesium, or external sodium with lithium, choline or dextrose. Replacing b... | ['Animals', 'Axons', 'Biological Transport, Active', 'Calcium', 'Calcium Isotopes', 'Cyanides', 'Cytoplasm', 'Dialysis', 'Ethers', 'Imides', 'In Vitro Techniques', 'Kinetics', 'Mollusca', 'Sodium', 'Time Factors'] | 5,764,408 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G03.143.310'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.552.100.500', 'D01.496.098', 'D01.552.539.288.500'], ['D01.248.497.158.291', 'D01.625.400.100'], ['A11.284.430.214'], ['E05.196.353', 'G02.186'], ['D0... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis of discrepancies between clinical and autopsy diagnoses in 188 cases]. | OBJECTIVE: To analyze the discrepancies between clinical and autopsy diagnoses in hospitals of different grades and with respect to duration of hospitalization.METHODS: A total of 188 autopsy cases collected from hospitals of different grades were retrospectively reviewed and the discrepancies between clinical and auto... | ['Adult', 'Aged', 'Aortic Aneurysm', 'Autopsy', 'Cause of Death', 'Diagnostic Errors', 'Female', 'Hospitals, Community', 'Hospitals, General', 'Hospitals, Teaching', 'Humans', 'Infections', 'Length of Stay', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocarditis', 'Pulmonary Embolism', 'Retrospective Studies', 'Y... | 19,781,340 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.055.239', 'C14.907.109.139'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E01.354', 'N02.421.450.280'], ['N02.278.421.306'], ['N02.278.421.389'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Voltammetric determination of cefixime in pharmaceuticals and biological fluids. | Electroreduction and adsorption of cefixime was studied in phosphate buffer by cyclic voltammetry (CV), differential pulse cathodic adsorptive stripping voltammetry (DPCAdSV), and square-wave cathodic adsorptive stripping voltammetry (SWCAdSV) at hanging mercury drop electrode (HMDE). These fully validated sensitive an... | ['Adsorption', 'Anti-Bacterial Agents', 'Cefixime', 'Electrochemical Techniques', 'Electrodes', 'Humans', 'Hydrogen-Ion Concentration', 'Reproducibility of Results', 'Tablets'] | 20,678,464 | [['G01.030', 'G02.020'], ['D27.505.954.122.085'], ['D02.065.589.099.249.190.190.115', 'D02.886.665.074.190.190.115', 'D03.633.100.300.249.190.190.115'], ['E05.301'], ['E07.305.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapid genetic analysis of epithelial-mesenchymal signaling during hair regeneration. | Hair follicle morphogenesis, a complex process requiring interaction between epithelia-derived keratinocytes and the underlying mesenchyme, is an attractive model system to study organ development and tissue-specific signaling. Although hair follicle development is genetically tractable, fast and reproducible analysis ... | ['Animals', 'Cell Communication', 'Epithelial Cells', 'Female', 'Hair Follicle', 'Keratinocytes', 'Mesoderm', 'Mice', 'Mice, Nude', 'Regeneration', 'Signal Transduction', 'Skin'] | 23,486,463 | [['B01.050'], ['G04.085'], ['A11.436'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['A11.409.500', 'A11.436.397'], ['A16.504.660'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['G16.762'], ['G02.111.820', 'G04.835'], ['A17.815']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage. | To gain further knowledge of the molecular features of topoisomerase II inhibitors required for drug-receptor complex formation, we investigated the conformational drug determinants of the sequence specificities of drug-stimulated DNA cleavage by computer-aided molecular modeling techniques. DNA sequence specificities ... | ['Anthracenes', 'Anthraquinones', 'Antineoplastic Agents', 'Computer Graphics', 'DNA', 'DNA Topoisomerases, Type II', 'Electrophoresis, Polyacrylamide Gel', 'Ellipticines', 'Genistein', 'Intercalating Agents', 'Isoflavones', 'Models, Molecular', 'Molecular Conformation', 'Pyrazoles', 'Receptors, Drug', 'Structure-Activ... | 8,308,885 | [['D02.455.426.559.847.117', 'D04.615.117'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['D27.505.954.248'], ['L01.224.108', 'L01.296.110'], ['D13.444.308'], ['D08.811.399.403.741'], ['E05.196.401.402', 'E05.301.300.319'], ['D03.132.436.681.333', 'D03.633.100.473.144.249', 'D03.633.100.473.402.6... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Predictors of anxiety among pregnant New Zealand women hospitalised for complications and a community comparison group. | OBJECTIVE: to investigate predictors of anxiety for women experiencing hospitalisation during pregnancy and a comparison group of pregnant women (with or without medical complications) in the community.DESIGN: correlational, cross-sectional observational questionnaire study.SETTING: regional antenatal inpatient unit an... | ['Adaptation, Psychological', 'Adult', 'Anxiety', 'Attitude to Health', 'Comorbidity', 'Female', 'Hospitalization', 'Humans', 'New Zealand', 'Pregnancy', 'Pregnancy Complications', 'Pregnant Women', 'Prenatal Care', 'Surveys and Questionnaires', 'Young Adult'] | 25,987,104 | [['F01.058'], ['M01.060.116'], ['F01.470.132'], ['F01.100.150', 'N05.300.150'], ['N05.715.350.225', 'N06.850.490.687'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.678.100.747'], ['G08.686.784.769'], ['C13.703'], ['M01.975.807'], ['E02.760.786', 'N02.421... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A chemically induced rat model of hemolysis with disseminated thrombosis. | Although hemolytic anemia and thrombosis, which can be serious or even lethal, are often encountered in daily common practice, their pathogenesis has remained obscure, partially because of the absence of appropriate models. Here we present a unique chemically induced rat model of hemolytic anemia and disseminated throm... | ['Animals', 'Body Weight', 'Disease Models, Animal', 'Ethylene Glycols', 'Female', 'Hemolysis', 'Male', 'Organ Size', 'Rats', 'Rats, Inbred F344', 'Sex Factors', 'Spleen', 'Thrombosis'] | 12,665,664 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.033.455.250'], ['C23.550.403', 'G12.122.545'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['B... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Posterior fossa extraaxial cyst: diagnosis with metrizamide CT cisternography. | This study describes a new technique for the study of posterior fossa extraaxial cysts. Using metrizamide (Amipaque) CT cisternography, a rapid, simple, low morbidity method is now available which gives both anatomic and physiologic information that may obviate the need for pneumoencephalography and angiography. Two ca... | ['Adult', 'Brain Diseases', 'Contrast Media', 'Cysts', 'Humans', 'Infant', 'Injections, Spinal', 'Iodobenzoates', 'Male', 'Metrizamide', 'Myelography', 'Tomography, X-Ray Computed'] | 402,836 | [['M01.060.116'], ['C10.228.140'], ['D27.505.259.500', 'D27.720.259'], ['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.319.267.530.580'], ['D02.241.223.100.400', 'D02.455.426.559.389.127.375'], ['D02.241.223.100.400.880.520', 'D02.455.426.559.389.127.375.880.520', 'D0... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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