Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The effect of chronic atypical antipsychotic drugs and haloperidol on amphetamine-induced dopamine release in vivo. | The effect of chronic administration of antipsychotic drugs (21 days in drinking water followed by 3 days drug washout) on the D-amphetamine (1.0 mg/kg, s.c.)-induced increase in dopamine (DA) release in the striatum and the nucleus accumbens of awake, freely-moving rats was investigated with microdialysis. Chronic adm... | ['3,4-Dihydroxyphenylacetic Acid', 'Animals', 'Antipsychotic Agents', 'Corpus Striatum', 'Dextroamphetamine', 'Dialysis', 'Dopamine', 'Haloperidol', 'Homovanillic Acid', 'Hydroxyindoleacetic Acid', 'Male', 'Nucleus Accumbens', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 1,379,112 | [['D02.241.223.601.220'], ['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['A08.186.211.200.885.287.249.487'], ['D02.092.471.683.152.110.200'], ['E05.196.353', 'G02.186'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D02.522... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative study of the CCF-like pattern recognition protein in different Lumbricid species. | Coelomic fluid of the Lumbricid Eisenia fetida contains a 42-kDa pattern recognition protein named coelomic cytolytic factor (CCF) that binds microbial cell wall components and triggers the activation of the prophenoloxidase cascade, an important invertebrate defense pathway. Here we report on the sequence characteriza... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Catechol Oxidase', 'Cell Line, Tumor', 'Cytotoxins', 'Disaccharides', 'Enzyme Precursors', 'Humans', 'Lectins', 'Molecular Sequence Data', 'Oligochaeta', 'Phylogeny', 'Random Amplified Polymorphic DNA Technique', 'Sequence Alignment', 'Substrate Specificity'] | 16,386,303 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.682.690.708.125'], ['A11.251.210.190', 'A11.251.860.180'], ['D27.888.569.213'], ['D09.698.629.305', 'D09.947.750'], ['D08.622', 'D12.776.811.243'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Opticociliary veins in a primary optic nerve sheath meningioma. | A 59-year-old man developed painless visual loss in his left eye over a one-year period, with rapid progression to blindness over three months. Ocular examination of the left eye revealed proptosis, marked optic disk pallor, dilated retinal veins, and congeries of vessels at the disk margin (opticociliary veins). His r... | ['Cranial Nerve Neoplasms', 'Fluorescein Angiography', 'Humans', 'Male', 'Meningeal Neoplasms', 'Meningioma', 'Middle Aged', 'Optic Nerve', 'Optic Nerve Diseases', 'Orbital Neoplasms', 'Retinal Vein'] | 434,059 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of continuous positive airway pressure on blood pressure and metabolic profile in women with sleep apnoea. | Continuous positive airway pressure (CPAP) reduces blood pressure levels in hypertensive patients with obstructive sleep apnoea (OSA). However, the role of CPAP in blood pressure and the metabolic profile in women has not yet been assessed. In this study we investigated the effect of CPAP on blood pressure levels and t... | ['Aged', 'Blood Pressure', 'Continuous Positive Airway Pressure', 'Female', 'Humans', 'Lipids', 'Metabolome', 'Middle Aged', 'Sleep Apnea, Obstructive', 'Spain'] | 28,798,089 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['G03.500'], ['M01.060.116.630'], ['C08.618.085.852.850', 'C10.886.425.800.750.850'], ['Z01.542.846']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Borax Alleviates Copper-Induced Renal Injury via Inhibiting the DNA Damage and Apoptosis in Rainbow Trout. | The aim of this study was to determine the therapeutic potential of borax against copper in the kidney tissue of the rainbow trout fed with added borax (BX) (1.25, 2.5, and 5 mg/kg) and/or copper (Cu) (500,1000 mg/kg) contents. For this purpose, two treatment groups had designed, and glutathione peroxidase (GPx), super... | ['Animals', 'Antioxidants', 'Apoptosis', 'Borates', 'Catalase', 'Copper', 'DNA Damage', 'Glutathione Peroxidase', 'HSP70 Heat-Shock Proteins', 'Kidney Diseases', 'Malondialdehyde', 'Oncorhynchus mykiss', 'Oxidation-Reduction', 'Superoxide Dismutase'] | 30,612,301 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['D01.132.250.075', 'D01.248.497.158.076', 'D02.203.130.075'], ['D08.811.682.732.332'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G05.200'], ['D08.811.682.732.500'], ['D12.776.580.216.375'], ['C12.777.41... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
From empathic mind to moral behaviour: the "who", "why" and "how". | In this paper, I start by suggesting a new definition of empathy. I go on by answering the question of "Who feels empathy?". I list some examples of people, illustrating how the level of feeling empathy differs from one category of people to another. It's actually almost everybody who feels empathy: the baby, the good ... | ['Behavior', 'Brain', 'Cognition', 'Empathy', 'Human Development', 'Humans', 'Morals', 'Philosophy, Medical', 'Psychology, Developmental'] | 26,924,202 | [['F01.145'], ['A08.186.211'], ['F02.463.188'], ['F01.752.355', 'F01.752.543.500.500'], ['F01.525', 'G07.345.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.500', 'K01.752.566'], ['K01.752.667'], ['F04.096.628.270']] | ['Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Humanities [K]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Follow-up in mitral valve prolapse by phonocardiography, M-mode and two-dimensional echocardiography and Doppler echocardiography. | To assess the serial phonocardiographic and echocardiographic change in patients with mitral valve prolapse (MVP), phonocardiograms and echocardiograms were reviewed retrospectively in 116 patients (48 men and 68 women, mean age 27 years) who had been determined to have MVP and were reexamined 4.3 years (range 1 to 14)... | ['Adult', 'Echocardiography', 'Echocardiography, Doppler', 'Female', 'Follow-Up Studies', 'Heart Murmurs', 'Humans', 'Male', 'Mitral Valve Insufficiency', 'Mitral Valve Prolapse', 'Phonocardiography', 'Retrospective Studies', 'Time Factors'] | 2,301,263 | [['M01.060.116'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.888.447'], ['B01.050.150... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossovers. | Crossovers (COs) between homologous chromosomes ensure their faithful segregation during meiosis. We identify C. elegans COSA-1, a cyclin-related protein conserved in metazoa, as a key component required to convert meiotic double-strand breaks (DSBs) into COs. During late meiotic prophase, COSA-1 localizes to foci that... | ['Animals', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'Chromosomes', 'Crossing Over, Genetic', 'Cyclins', 'DNA Breaks, Double-Stranded', 'DNA-Binding Proteins', 'Meiosis', 'Models, Molecular', 'Mutation'] | 22,464,324 | [['B01.050'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['G05.728.615.200'], ['D12.644.360.262', 'D12.776.167.218', 'D12.776.476.262'], ['G05.200.210.220'], ['D12.776.260'], ['G04.144.220.220.687', 'G05.113.220.687'], ['E05.599.595']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exogenous calcium preconditions myocardium from patients taking oral sulfonylurea agents. | We have previously reported that atrial trabeculae from patients taking oral sulfonylurea hypoglycemic agents cannot be preconditioned by transient ischemia, which may, in part, explain the increased cardiovascular mortality historically associated with the use of these agents (J. C. Cleveland et al., 1997, Circulation... | ['Administration, Oral', 'Atrial Function', 'Calcium', 'Humans', 'Hypoglycemic Agents', 'In Vitro Techniques', 'Ischemic Preconditioning, Myocardial', 'Myocardial Contraction', 'Myocardial Ischemia', 'Myocardial Reperfusion Injury', 'Sulfonylurea Compounds'] | 10,534,420 | [['E02.319.267.100'], ['G09.330.040'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['E05.481'], ['E02.592.325', 'E05.516.325'], ['G09.330.580', 'G11.427.494.570'], ['C14.280.647', 'C14.907.585'], ['C14.280.238.615', 'C14.280.647.625', 'C14... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TLR and nucleotide-binding oligomerization domain-like receptor signals differentially regulate exogenous antigen presentation. | The effect of dendritic cell (DC) maturation on MHC class II-restricted Ag presentation is well studied, but less is known about the effects of DC maturation on MHC class I-restricted cross-presentation. We investigated the ability of mature DCs to present Ags from cells infected with HSV-1. Pretreatment with pure LPS ... | ['Animals', 'Cells, Cultured', 'Coculture Techniques', 'Cross-Priming', 'HeLa Cells', 'Humans', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nod1 Signaling Adaptor Protein', 'Nod2 Signaling Adaptor Protein', 'Peptidoglycan', 'Protein Structure, Tertiary', 'Signal Transduction', 'Toll-Like Receptor 2', 'Toll-Like Re... | 22,156,493 | [['B01.050'], ['A11.251'], ['E05.481.500.374'], ['G12.450.050.400.545.150', 'G12.565.150'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Theoretical study of the regioselective cyclization of enaminones in the construction of benzofurans and indoles. | A theoretical study was undertaken regarding the regioselective Lewis acid-promoted intramolecular cyclization of novel enaminones 1-3 leading to the corresponding benzofurans 4-5 and indoles 6. The density functional theory (DFT) and hard and soft acids and bases (HSAB) principle provided data to describe the electron... | ['Benzofurans', 'Cyclization', 'Indoles', 'Models, Molecular', 'Molecular Conformation', 'Naphthoquinones', 'Quantum Theory', 'Regression Analysis', 'Stereoisomerism', 'Thermodynamics'] | 27,132,239 | [['D03.633.100.127'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['D03.633.100.473'], ['E05.599.595'], ['G02.111.570.820'], ['D02.455.426.559.847.638.721', 'D02.806.550', 'D04.615.638.721'], ['H01.671.579.800'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['G02.607.445.682'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Two subtypes of symptomatic joint hypermobility: a descriptive study using latent class analysis. | OBJECTIVE: To investigate a cohort of children with symptomatic joint hypermobility.METHODS: Case notes for 318 children with joint hypermobility attending a rheumatology clinic were reviewed for clinical presentation, medical history, psychosocial factors and physical examination findings. Seven key variables were ext... | ['Arthralgia', 'Child', 'Decision Making', 'Exercise', 'Female', 'Humans', 'Joint Instability', 'Joints', 'Latent Class Analysis', 'Male', 'Pain Measurement', 'Prevalence', 'Western Australia'] | 30,120,142 | [['C05.550.091', 'C23.888.592.612.094', 'F02.830.816.444.350', 'G11.561.790.444.350'], ['M01.060.406'], ['F02.463.785.373'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['A02.835.583'], ['E05.318.740.250.338', 'G17.035.625', 'L01.224.050.687', 'N05.715.360.750.2... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geog... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Visual P3a in male subjects at high risk for alcoholism. | BACKGROUND: Voltage of the P300 component of event-related potentials (ERPs) has been proposed as a phenotypic marker of risk for alcoholism. P3a elicited by intrusive events is important in the context of deficits in inhibition found during psychophysiological and behavioral evaluations in children of alcoholics.METHO... | ['Adult', 'Alcoholism', 'Brain Mapping', 'Event-Related Potentials, P300', 'Evoked Potentials, Visual', 'Frontal Lobe', 'Humans', 'Male', 'Parietal Lobe', 'Risk Factors', 'Temporal Lobe'] | 10,418,704 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G07.265.216.500.350', 'G11.561.200.500.350'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification and characterization of a 27 kDa acrosome protein of human sperm defined by a monoclonal antibody with fertilization-blocking effect. | A monoclonal antibody, MAb 1G1, possessing a strong fertilization-blocking activity was prepared by immunizing a BALB/c mouse with capacitated human sperm in order to study the molecular nature of sperm antigens relevant to fertilization. MAb 1G1 inhibited human sperm penetration into zona-free hamster eggs. It reacted... | ['Acrosome', 'Animals', 'Antibodies, Monoclonal', 'Cattle', 'Contraception, Immunologic', 'Cricetinae', 'Female', 'Humans', 'Macaca', 'Male', 'Membrane Proteins', 'Mice', 'Mice, Inbred BALB C', 'Molecular Weight', 'Species Specificity', 'Sperm-Ovum Interactions', 'Swine'] | 7,932,391 | [['A05.360.490.890.820.100', 'A11.284.430.214.190.875.190.550.040', 'A11.497.760.400.100'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.500.380.271'], ['E02.875.194.300'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum level of interleukin-16 in multiple myeloma patients and its relationship to disease activity. | Interleukin-16 (IL-16) is a chemoattractant of CD4+ lymphocytes, and it has been implicated in the pathogenesis of various inflammatory diseases. There is evidence that it may have a role in multiple myeloma (MM). In the present study, we determined the serum level of IL-16 both before and after treatment of MM and rel... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Biomarkers', 'Female', 'Follow-Up Studies', 'Humans', 'Inflammation', 'Interleukin-16', 'Male', 'Middle Aged', 'Multiple Myeloma', 'Neoplasm Staging', 'Reference Values', 'Survival Analysis', 'Time Factors'] | 14,755,377 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D23.101'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.516',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of magnetic resonance imaging in coarctation of the aorta: the importance of multiple imaging planes. | Coarctation of the aorta can be evaluated reliably and noninvasively by magnetic resonance imaging. However, the value of different imaging planes in the evaluation of restenosis or aneurysm has not previously been studied. Our purpose was to study the relative sensitivity for oblique coronal and oblique parasagittal m... | ['Angioplasty, Balloon', 'Aortic Aneurysm, Thoracic', 'Aortic Coarctation', 'Child', 'Humans', 'Magnetic Resonance Imaging', 'Postoperative Complications', 'Recurrence'] | 9,270,101 | [['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['C14.240.400.090', 'C14.280.400.090', 'C16.131.240.400.090'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C23.550.767'], ['C23.550.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reversal of age-related learning deficiency by the vertebrate PACAP and IGF-1 in a novel invertebrate model of aging: the pond snail (Lymnaea stagnalis). | With the increase of life span, nonpathological age-related memory decline is affecting an increasing number of people. However, there is evidence that age-associated memory impairment only suspends, rather than irreversibly extinguishes, the intrinsic capacity of the aging nervous system for plasticity (1). Here, usin... | ['Aging', 'Animals', 'Brain', 'Humans', 'Insulin-Like Growth Factor I', 'Learning', 'Lymnaea', 'Memory', 'Memory, Long-Term', 'Models, Animal', 'Pituitary Adenylate Cyclase-Activating Polypeptide', 'Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide'] | 24,846,768 | [['G07.345.124'], ['B01.050'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['F02.463.425', 'F02.784.629.529'], ['B01.050.500.644.400.750.645'], ['F02.463.425.540'], ['F02.463.425.540.305'], ['E05.598'], ['D12... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of Tomato planta macho viroid in germinating pollen and transmitting tract. | Vertical and horizontal pollen transmission is important for efficient infection by viroids. Vertical pollen transmission of viroids is attributed to the infection by viroid in the embryo sac through infected pollen. To identify the viroid infection in pollen and pollen tubes elongating through the transmitting tract, ... | ['Cell Nucleus', 'In Situ Hybridization', 'Petunia', 'Plant Viruses', 'Pollen'] | 28,942,579 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['B01.650.940.800.575.912.250.908.500.448'], ['B04.715'], ['A18.024.249.500.249.500']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical and biological organ dosimetry analysis for international space station astronauts. | In this study, we analyzed the biological and physical organ dose equivalents for International Space Station (ISS) astronauts. Individual physical dosimetry is difficult in space due to the complexity of the space radiation environment, which consists of protons, heavy ions and secondary neutrons, and the modification... | ['Astronauts', 'Cells, Cultured', 'Humans', 'In Situ Hybridization, Fluorescence', 'Internationality', 'Models, Biological', 'Radiometry', 'Spacecraft', 'Whole-Body Irradiation'] | 18,582,161 | [['M01.526.173'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['I01.615'], ['E05.599.395'], ['E05.799'], ['J01.937.285.850.900... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
Lipoma induced jejunojejunal intussusception. | Intussusception in adults is rare. The clinical picture of intussusception in adults is subtle and the diagnosis is, therefore, elusive. The presence of a structural abnormality in the great majority of the adult cases mandates high clinical suspicion. Gastrointestinal lipomas are rare benign tumors and intussusception... | ['Abdominal Pain', 'Digestive System Surgical Procedures', 'Gastrointestinal Hemorrhage', 'Humans', 'Intussusception', 'Jejunal Diseases', 'Jejunal Neoplasms', 'Lipoma', 'Male', 'Middle Aged', 'Treatment Outcome'] | 17,659,719 | [['C23.888.592.612.054', 'C23.888.821.030'], ['E04.210'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531.577'], ['C06.405.469.600'], ['C04.588.274.476.411.523', 'C06.301.371.411.523', 'C06.405.249.411.523', 'C06.405.469.491.523', 'C06.405.469.600.523'], ['C04.557.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MreC and MreD Proteins Are Not Required for Growth of Staphylococcus aureus. | The transmembrane proteins MreC and MreD are present in a wide variety of bacteria and are thought to be involved in cell shape determination. Together with the actin homologue MreB and other morphological elements, they play an essential role in the synthesis of the lateral cell wall in rod-shaped bacteria. In ovococc... | ['Bacterial Proteins', 'Cell Division', 'Genes, Bacterial', 'Genes, Essential', 'Peptidoglycan', 'Staphylococcus aureus'] | 26,470,021 | [['D12.776.097'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.340.270'], ['D09.400.420.700', 'D09.698.718.594', 'D12.644.233.594', 'D12.776.395.560.800', 'D23.050.161.616.594'], ['B03.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bioelectric phenomena related to protein-fixed charge in a crab nerve fiber. | The bioelectrical characteristics of a crab nerve fiber subjected to solutions containing the impermeant anions ferrocyanide, glutamate, or ethanolsulfate substituted for chloride include prolonged slow depolarizations that elicit prolonged trains of impulses sulperimposed on the plateau portion. Propionate and nitrate... | ['Action Potentials', 'Animals', 'Chlorides', 'Crustacea', 'Electrophysiology', 'Ethanol', 'Ferrocyanides', 'Glutamates', 'In Vitro Techniques', 'Nerve Tissue Proteins', 'Neurons', 'Nitrates', 'Potassium', 'Propionates', 'Sodium', 'Sulfates', 'Thiocyanates'] | 6,021,041 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D01.210.450.150', 'D01.248.497.158.215'], ['B01.050.500.131.365'], ['H01.158.344.528', 'H01.158.782.236'], ['D02.033.375'], ['D01.248.497.158.291.370', 'D01.490.200.250', 'D01.625.400.100.350'], ['D12.125.067.625', 'D12.125.119.409'], ['E05.481'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Renovation of the WWTP hove. | The provision of reliable treatment has always been a priority in sanitary engineering. However, there is an ever-increasing pressure to meet desirable standards at reduced costs. This paper sets out a methodology to enhance the likelihood of a satisfactory allocation of the resources while providing reliable treatment... | ['Belgium', 'Conservation of Natural Resources', 'Models, Theoretical', 'Monte Carlo Method', 'Sanitary Engineering', 'Waste Disposal, Fluid'] | 15,954,569 | [['Z01.542.115'], ['J01.256', 'N06.230.080'], ['E05.599'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['H02.229.656', 'J01.293.821', 'N06.850.780.200.800.800', 'N06.850.860.510'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900']] | ['Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Predictors of smoking onset over two years. | The objective of this analysis was to identify variables that predict the initiation of smoking among adolescents, and the development of susceptibility to smoking, over a 2-year period. We assessed variables that might predict later smoking among nonsmoking students in grades 7 and 9 and assessed their smoking status ... | ['Adolescent', 'Adolescent Behavior', 'Age of Onset', 'Attitude to Health', 'Cross-Sectional Studies', 'Family Relations', 'Female', 'Health Behavior', 'Humans', 'Male', 'Multivariate Analysis', 'Peer Group', 'Risk-Taking', 'Self Concept', 'Smoking', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Tobacco Use D... | 18,058,344 | [['M01.060.057'], ['F01.145.022'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['F01.100.150', 'N05.300.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.829.263.370', 'I01.880.853.150.439'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.15... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Tobacco use among married women in Nepal: the role of women's empowerment. | This study documented the prevalence and correlates of tobacco use among women of reproductive age in Nepal using nationally representative data. We utilized the 2006 Nepal Demographic and Health Survey that interviewed 10,793 women and 4,397 men. We analyzed the couple's data or households (N = 2,600) in which both hu... | ['Adolescent', 'Adult', 'Age Distribution', 'Educational Status', 'Employment', 'Female', 'Health Surveys', 'Humans', 'Male', 'Marriage', 'Middle Aged', 'Nepal', 'Population Surveillance', 'Power, Psychological', 'Prevalence', 'Residence Characteristics', 'Smoking', 'Social Environment', 'Socioeconomic Factors', 'Tobac... | 22,527,772 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N01.824.196'], ['N01.824.245'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Functional levels and nurse workload of elderly awaiting nursing home placement and nursing home residents: a comparative study. | The aim of this study was twofold: to compare the functional levels of elderly awaiting nursing home placement and nursing home residents, and to compare their nurses' physical and psychological workloads. In Norway, the demand for nursing home placement has increased greatly. Elderly awaiting placement can receive car... | ['Adult', 'Aged', 'Catchment Area, Health', 'Cognition Disorders', 'Female', 'Humans', 'Male', 'Norway', 'Nurses', 'Nursing Homes', 'Severity of Illness Index', 'Surveys and Questionnaires', 'Waiting Lists', 'Workload'] | 19,740,113 | [['M01.060.116'], ['M01.060.116.100'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.374'], ['M01.526.485.650', 'N02.360.650'], ['N02.278.825.610'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.5... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Spectrum of UGT1A1 Variations in Chinese Patients with Crigler-Najjar Syndrome Type II. | Crigler-Najjar Syndrome type II (CNS-II) is an autosomal recessive hereditary condition of unconjugated hyperbilirubinemia without hemolysis, with bilirubin levels ranging from 102.6 ìmol/L to 342 ìmol/L. CNS-II is caused by a deficiency of UDP-glucuronyl transferase (UGT), which is encoded by the UDP-glucuronyl transf... | ['Adolescent', 'Adult', 'Asian Continental Ancestry Group', 'Bilirubin', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Crigler-Najjar Syndrome', 'Enhancer Elements, Genetic', 'Female', 'Gene Expression', 'Genetic Variation', 'Genotype', 'Glucuronosyltransferase', 'Homozygote', 'Humans', 'Infant', 'Male', 'Middl... | 25,993,113 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.200'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['C16.320.565.300.281', 'C18.452.648.300.281'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characteristics of children with elevated symptoms of mania: the Longitudinal Assessment of Manic Symptoms (LAMS) study. | OBJECTIVE: The aim of the Longitudinal Assessment of Manic Symptoms (LAMS) study is to examine differences in psychiatric symptomatology, diagnoses, demographics, functioning, and psychotropic medication exposure in children with elevated symptoms of mania (ESM) compared to youth without ESM. This article describes the... | ['Anxiety', 'Attention Deficit Disorder with Hyperactivity', 'Attention Deficit and Disruptive Behavior Disorders', 'Bipolar Disorder', 'Case-Control Studies', 'Child', 'Depression', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Mood Disorders', 'Ohio', 'P... | 21,034,685 | [['F01.470.132'], ['F03.625.094.150'], ['F03.625.094'], ['F03.084.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['F01.145.126.350'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Outside-the-ribcage thoracic migration of a spigelian hernia. | Lung and spigelian hernia are both extremely rare diseases, and their combined and simultaneous appearance in the same patient, causing the small bowel to shift from the abdomen towards the thorax external to the ribcage is even more unusual. Here, we report such a case, supported by comprehensive iconography and a det... | ['Aged', 'Diagnosis, Differential', 'Follow-Up Studies', 'Hernia, Ventral', 'Humans', 'Intestinal Obstruction', 'Intestine, Small', 'Laparotomy', 'Male', 'Prosthesis Implantation', 'Radiography, Abdominal', 'Surgical Mesh', 'Thoracic Cavity', 'Thoracoplasty', 'Tomography, X-Ray Computed'] | 18,584,281 | [['M01.060.116.100'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.300.707.374.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['A03.556.124.684'], ['E04.406'], ['E04.650'], ['E01.370.350.700.715'], ['E07.858.708'], ['A01.923.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of semi-rigid arch-support orthotics: an investigation with potential ergonomic implications. | For many years, arch-support orthotics have been prescribed for individuals with discomfort and/or abnormal skeletal alignments in the structures of the lower extremity. Recently there has been an increased interest in promoting semi-rigid orthotics as an ergonomic aid for asymptomatic workers who must stand all day at... | ['Adult', 'Analysis of Variance', 'Anthropometry', 'Biomechanical Phenomena', 'Ergonomics', 'Fatigue', 'Female', 'Foot', 'Humans', 'Male', 'Muscles', 'Orthotic Devices', 'Polyurethanes', 'Posture', 'Shoes', 'Time Factors'] | 11,059,465 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['G01.154.090', 'G01.374.089'], ['F02.784.412', 'J01.293.556'], ['C23.888.369'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633', 'A10.690'], ['E07... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Differential diagnostics in patients with mild lumbar spinal stenosis: the contributions and limits of various tests. | Lumbar spinal stenosis (LSS) and diabetic polyneuropathy are common ailments of older age. Many people suffer from both at the same time. In such patients it may sometimes be difficult to separate signs and symptoms that could be attributed to either disease. This study evaluates the contributions and limits of various... | ['Diabetic Neuropathies', 'Diagnosis, Differential', 'Electromyography', 'Electrophysiology', 'Evoked Potentials, Motor', 'Exercise Test', 'Female', 'H-Reflex', 'Humans', 'Intermittent Claudication', 'Lumbosacral Region', 'Male', 'Middle Aged', 'Prospective Studies', 'Radiography', 'Spinal Stenosis', 'Upper Extremity'] | 12,709,857 | [['C10.668.829.300', 'C19.246.099.937'], ['E01.171'], ['E01.370.405.255', 'E01.370.530.255'], ['H01.158.344.528', 'H01.158.782.236'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['G11.561.731.643.474'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of preterm and full-term infants on auditory discrimination at four months and on Bayley Scales of Infant Development at eighteen months. | A variable-trials auditory discrimination procedure was employed to measure individual differences in stimulus encoding and memory among 4-month-old preterm and full-term infants who were equated on conceptional age. It was assumed that differences among individuals on this task would be predictive of cognitive functio... | ['Acoustic Stimulation', 'Auditory Perception', 'Child Development', 'Discrimination Learning', 'Female', 'Heart Rate', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Psychological Tests', 'Psychology, Child'] | 7,363,752 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['F02.463.593.071', 'G07.888.125'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.425.280'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['F04.711'], ['F04.096.628.193']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The association between maternal-reported responses to infant crying at 4 weeks and 6 months and offspring depression at 18: a longitudinal study. | The purpose of the present study is to examine the association between maternal response to infant crying and the psychological health of the child in later life. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort, consisting of 15,247 pregnancies, 10,278 with exposure variables and 320... | ['Adult', 'Child', 'Crying', 'Depression', 'Female', 'Humans', 'Infant', 'Longitudinal Studies', 'Male', 'Maternal Behavior', 'Mental Health', 'Mother-Child Relations', 'Mothers', 'Parents'] | 26,837,614 | [['M01.060.116'], ['M01.060.406'], ['F01.145.209.530.258', 'F01.525.200.310.300'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['F01.829.263.370.215'], ['F02.418', 'N01.400.500'], ['F01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Gliocyte and synapse analyses in cerebral ganglia of the Chinese mitten crab, Eriocheir sinensis: ultrastructural study. | The Chinese mitten crab Eriocheir sinensis is an economically important aquatic species in China. Many studies on gene structure, breeding, and diseases of the crab have been reported. However, knowledge about the organization of the nerve system of the crab remains largely unknown. To study the ultrastructure of the c... | ['Animals', 'Brachyura', 'Ganglia', 'Neuroglia', 'Synapses'] | 27,734,995 | [['B01.050'], ['B01.050.500.131.365.190.110'], ['A08.340'], ['A08.637', 'A11.650'], ['A08.850', 'A11.284.149.165.420.780']] | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro selection of RNA aptamers that selectively bind danofloxacin. | Danofloxacin is a synthetic fluoroquinolone with broad spectrum antibacterial activity that is used for the treatment of respiratory diseases in animal husbandry. However, danofloxacin has many adverse reactions and is toxic to humans. Especially, it detrimentally affects muscle, central nerve system, peripheral nerve ... | ['Animal Husbandry', 'Animals', 'Anti-Bacterial Agents', 'Aptamers, Nucleotide', 'Base Sequence', 'Drug Residues', 'Fluoroquinolones', 'Food Contamination', 'Humans', 'Nucleic Acid Conformation', 'SELEX Aptamer Technique', 'Surface Plasmon Resonance'] | 24,792,181 | [['J01.040.090'], ['B01.050'], ['D27.505.954.122.085'], ['D13.695.578.424.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['N06.850.460.200.250'], ['D03.633.100.810.835.322'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Diagnostic performance of resting CT myocardial perfusion in patients with possible acute coronary syndrome. | OBJECTIVE: Coronary CT angiography has high sensitivity, but modest specificity, to detect acute coronary syndrome. We studied whether adding resting CT myocardial perfusion imaging improved the detection of acute coronary syndrome.SUBJECTS AND METHODS: Patients with low-to-intermediate cardiac risk presenting with pos... | ['Acute Coronary Syndrome', 'Coronary Angiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Perfusion Imaging', 'Prevalence', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed', 'Washington'] | 23,617,513 | [['C14.280.647.124', 'C14.907.585.124'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.130.875', 'E01.370.350.710.600.500', 'E01.370.370.380.500', 'E01.370.384.730.354.500'], ['E05.318... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Removal of epulis fissuratum by Er,Cr:YSGG laser in comparison with the conventional method. | OBJECTIVE: The present study aimed to compare clinical outcomes during the recovery period after soft tissue surgery performed by an erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser with those after surgery with the conventional method, in which a scalpel was used.METHODS: A total of 44 epulis fissur... | ['Adult', 'Aged', 'Female', 'Gingival Diseases', 'Humans', 'Lasers, Solid-State', 'Male', 'Middle Aged', 'Treatment Outcome'] | 26,492,496 | [['M01.060.116'], ['M01.060.116.100'], ['C07.465.714.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490.490', 'E07.710.520.490'], ['M01.060.116.630'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tranexamic acid derivatives with enhanced absorption. | Derivatives of the antifibrinolytic drug tranexamic acid [trans-4-(aminomethyl)cyclohexanecarboxylic acid] containing one or two tranexamic acid moieties were synthesized. Most of the derivatives have good stability in acidic and neutral solutions but are easily hydrolyzed in plasma. By measuring the amount of tranexam... | ['Animals', 'Cyclohexanecarboxylic Acids', 'Intestinal Absorption', 'Male', 'Rats', 'Rats, Inbred Strains', 'Structure-Activity Relationship', 'Tranexamic Acid'] | 3,959,024 | [['B01.050'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G02.11... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells. | The transcription factor Evi1 has an outstanding role in the formation and transformation of hematopoietic cells. Its activation by chromosomal rearrangement induces a myelodysplastic syndrome with progression to acute myeloid leukemia of poor prognosis. Similarly, retroviral insertion-mediated upregulation confers a c... | ['Animals', 'Cell Cycle', 'Cell Differentiation', 'Cell Line', 'Cell Survival', 'DNA-Binding Proteins', 'Granulocyte Precursor Cells', 'Hematopoietic Stem Cells', 'Humans', 'MDS1 and EVI1 Complex Locus Protein', 'Mice', 'Mice, Inbred C57BL', 'Proto-Oncogenes', 'Transcription Factors'] | 23,212,151 | [['B01.050'], ['G04.144'], ['G04.152'], ['A11.251.210'], ['G04.346'], ['D12.776.260'], ['A11.148.350.350', 'A11.148.378.590.675.500', 'A11.627.340.360', 'A11.627.635.675.500', 'A11.872.378.590.635.500', 'A15.378.316.340.350', 'A15.378.316.378.590.675.500'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Share of Advertising Voice at the Point-of-Sale and Its Influence on At-Risk Students' Use of Alternative Tobacco Products. | INTRODUCTION: As adolescent tobacco use shifts from traditional cigarettes to alternative products, it is important to understand the influence of point-of-sale (POS) advertising on product use. This research investigated whether the percentage of POS advertising for a particular product, known as the share of advertis... | ['Adolescent', 'Advertising', 'California', 'Electronic Nicotine Delivery Systems', 'Female', 'Follow-Up Studies', 'Health Risk Behaviors', 'Humans', 'Longitudinal Studies', 'Male', 'Schools', 'Self Report', 'Students', 'Tobacco Products', 'Tobacco Use'] | 30,032,290 | [['M01.060.057'], ['J01.219.687.274', 'L01.143.050'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['J01.637.767.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.145.488.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', ... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Monoclonal antibody, KK1, recognizes human retinal astrocytes and distinguishes a subtype of astrocytes in mouse brain. | Astrocytes exhibit a diverse morphology and numerous functions in the central nervous system as well as in the retina. In order to obtain markers for the analysis of astrocytes, we prepared monoclonal antibodies that recognized antigens specific to astrocytes. Monoclonal antibody (mAb), designated KK1, reacted with the... | ['Animals', 'Antibodies, Monoclonal', 'Astrocytes', 'Brain', 'Glial Fibrillary Acidic Protein', 'Humans', 'Immunohistochemistry', 'Mice', 'Mice, Inbred Strains', 'Retina'] | 8,973,798 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Drug abuse in Denmark (Jutland and Funen). A forensic study based upon drugs seized in 1982-1987. | Two thousand fifty-three samples submitted to forensic chemical analysis during the period 1982-1987 were characterized according to their content of narcotics and the year of seizure. Heroin and cannabis dominated the material, but a significant decrease in the number of heroin samples was observed in 1987. Amphetamin... | ['Amphetamine', 'Cocaine', 'Cross-Sectional Studies', 'Denmark', 'Heroin Dependence', 'Humans', 'Illicit Drugs', 'Marijuana Abuse', 'Morphine Dependence', 'Substance-Related Disorders'] | 3,266,402 | [['D02.092.471.683.152.110'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.816.124'], ['C25.775.643.500.400', 'F03.900.647.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effect of stabilisation treatment of rice bran on nutritional quality of protein concentrates. | Protein concentrates were prepared from unstabilised, acid stabilised, heat stabilised and parboiled rice bran, either freeze dried or roller dried. They were assessed for their nutritional quality by both in vivo and in vitro assays. The essential amino acid profile of protein concentrates was comparable to rice prote... | ['Amino Acids', 'Desiccation', 'Dietary Proteins', 'Digestion', 'Drug Stability', 'Hot Temperature', 'Hydrochloric Acid', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Nitrogen', 'Nutritive Value', 'Oryza', 'Plant Proteins'] | 7,621,091 | [['D12.125'], ['E05.196.335', 'G02.176'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.250', 'G10.261.190'], ['E05.916.330'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D01.029.260.326', 'D01.210.450'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Removal of amitriptyline from simulated gastric and intestinal fluids using activated carbons. | In this work, the adsorption behavior of a tricyclic antidepressant, amitriptyline hydrochloride, onto several activated carbons (ACs) is reported. The adsorption was done using in vitro simulated gastric and intestinal fluid at 37°C to test the performance of the carbons as treatment in overdose cases. The tested mate... | ['Adsorption', 'Amitriptyline', 'Antidepressive Agents, Tricyclic', 'Body Fluids', 'Carbon', 'Charcoal', 'Drug Overdose', 'Gastric Mucosa', 'Humans', 'Hydrogen-Ion Concentration', 'Intestinal Mucosa'] | 21,918,986 | [['G01.030', 'G02.020'], ['D02.455.426.559.847.181.384.100', 'D04.615.181.384.100'], ['D27.505.954.427.700.122.055'], ['A12.207'], ['D01.268.150'], ['D01.268.150.150'], ['C25.775.383', 'E02.319.306.500.500'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['A03... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Parahippocampal Cortex Mediates Contextual Associative Memory: Evidence from an fMRI Study. | The parahippocampal cortex (PHC) plays a key role in episodic memory, spatial processing, and the encoding of novel stimuli. Recent studies proposed that the PHC is largely involved in contextual associative processing. Consequently, the function of this region has been a hot debate in cognitive neuroscience. To test t... | ['Adult', 'Brain Mapping', 'Cognition', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Memory, Episodic', 'Parahippocampal Gyrus', 'Photic Stimulation'] | 27,247,946 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['F02.463.425.540.254'], ['A08.186.211.180.590.750', 'A08.186.211.180.710', 'A08.186.211.200.885.287.500.382.750'], ['E05.723.729']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The UNOS Renal Transplant Registry. | Based upon data reported to the UNOS Renal Transplant Registry between 1998-2001, the overall one- and projected 10-year graft survival rates for 31,720 cadaveric kidney transplants were 89% and 51%, and for 14,162 living donor transplants they were 95% and 68%, respectively. These results represent improvements of 15%... | ['Graft Survival', 'Humans', 'Kidney Diseases', 'Kidney Transplantation', 'Registries', 'Reoperation', 'Survival Analysis', 'Time Factors', 'Tissue and Organ Procurement', 'Treatment Outcome'] | 12,971,433 | [['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['E04.690'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Analysis of a consecutive series of 421 cases of genital condylomata. Course, management and therapeutic results]. | The evolution of 421 cases of condylomata that have been followed seems to be less favourable than in other series in the literature. 45% of these cases became worse and 13% regressed, especially in the first year after diagnosis. Sometimes the case progresses in an atypical manner. It can be extremely rapid so that it... | ['Adolescent', 'Adult', 'Aged', 'Animals', 'Cell Transformation, Neoplastic', 'Condylomata Acuminata', 'Cricetinae', 'Female', 'Follow-Up Studies', 'Genital Neoplasms, Female', 'Humans', 'Laser Therapy', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Uterine Cervical N... | 3,833,904 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C01.221.812.640.220', 'C01.778.640.220', 'C01.925.256.650.810.217', 'C01.925.813.220', 'C01.925.825.810.110', 'C01.925.928.914.217', 'C17.800.838.790.810.110'], ['B01.050.150.900.649.313.992.635.075.250'],... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acute subdural haematoma: better results with neurosurgeons than general surgeons. | During an eleven year period, 123 patients with acute subdural haematoma were treated in our unit. The first 63 patients were managed by general surgeons with a mortality rate of 80.9 per cent. Good recovery among survivors was 4.7 per cent. The subsequent 60 patients were managed by neurosurgeons. The mortality rate t... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'General Surgery', 'Hematoma, Subdural', 'Hong Kong', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Neurosurgery', 'Retrospective Studies', 'Time Factors'] | 6,874,059 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['H02.403.810.300'], ['C10.228.140.300.535.450.400', 'C10.900.300.837.600', 'C14.907.253.573.400.450', 'C23.550.414.838.700', 'C23.550.414.913.700', 'C26.915.300.490.450'], ['Z01.252.474.164.450'], ['B01.0... | ['Diseases [C]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Accuracy of psychometric tools in the assessment of personality in adolescents and adults requesting gender-affirming treatments: A systematic review. | BACKGROUND: The assessment and screening for personality disorders in individuals requesting gender affirming treatments may be an important aspect of predicting medical and surgical outcomes for this population, but there is no consensus on how best to do so.AIMS: To review the diagnostic accuracy of psychometric tool... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Male', 'Personality', 'Psychometrics', 'Reproducibility of Results', 'Transgender Persons', 'Transsexualism'] | 31,546,228 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['M01.777.500'], ['F01.145.802.975.750']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Practitioner-client relationships in integrative medicine clinics in Australia: a contemporary social phenomenon. | OBJECTIVES: The increasing use of complementary and alternative medicine (CAM) in developed countries has been attributed more to contemporary cultural trends than to inherent problems in mainstream medicine. The aim of this study was to examine the impact of post-modern values on relationships between practitioners an... | ['Australia', 'Complementary Therapies', 'Delivery of Health Care, Integrated', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Interviews as Topic', 'New South Wales', 'Patient Acceptance of Health Care', 'Professional-Patient Relations', 'Social Values'] | 20,178,873 | [['Z01.639.100', 'Z01.678.100.373'], ['E02.190'], ['N04.590.374.142', 'N05.300.262'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['F01.100.150.7... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Isoniazid- and rifampin-resistant tuberculosis in San Diego County, California, United States, 1993-2002. | SETTING: A local tuberculosis (TB) control program.OBJECTIVES: To measure trends in isoniazid (INH) and rifampin (RMP) resistance and identify associated factors.DESIGN: Retrospective review.RESULTS: Of 2883 isolates obtained from TB patients reported between 1993 and 2002, 287 (10%) were resistant to INH, 11 (< 1%) we... | ['Adolescent', 'Adult', 'Antibiotics, Antitubercular', 'Antitubercular Agents', 'California', 'Child', 'Female', 'Humans', 'Isoniazid', 'Male', 'Multivariate Analysis', 'Retrospective Studies', 'Rifampin', 'Tuberculosis, Multidrug-Resistant', 'Tuberculosis, Pulmonary', 'United States'] | 15,875,920 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085.255.135'], ['D27.505.954.122.085.255'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['E05.318.740.150.500', 'N05.715.360.750.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Aplastic anaemia patients with clonal X-chromosome inactivation pattern in haemopoietic cells exhibit polyclonal TCRgamma and IgH gene rearrangements. | Previously, we reported that 13/18 (72%) female patients with aplastic anaemia (AA) exhibited a clonal X-chromosome inactivation (XCI) pattern in all haemopoietic lineages. To study the consequences of a clonal haemopoiesis for the randomness of immunoreceptor rearrangements in lymphocytes we determined clonality of T-... | ['Adult', 'Aged', 'Anemia, Aplastic', 'Base Sequence', 'Dosage Compensation, Genetic', 'Female', 'Gene Rearrangement', 'Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor', 'Genes, Immunoglobulin', 'Hematopoietic Stem Cells', 'Humans', 'Middle Aged', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Recepto... | 8,639,424 | [['M01.060.116'], ['M01.060.116.100'], ['C15.378.071.085', 'C15.378.190.223.250'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.203.249'], ['G05.344'], ['G05.344.801.311', 'G12.500.287.311'], ['G05.360.340.024.340.335', 'G12.500.299'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Comparing four methods to inform parents about child behavior management: how to inform for consent. | One hundred twenty parents were shown descriptions of eight traditional behavior management techniques via one of four different presentation methods: one of two types of video presentation, an oral presentation, or a written presentation. They were asked whether they felt well informed about each technique and asked f... | ['Analysis of Variance', 'Behavior Control', 'Behavior Therapy', 'Chi-Square Distribution', 'Child', 'Child Behavior', 'Child, Preschool', 'Consent Forms', 'Dental Care', 'Disclosure', 'Female', 'Humans', 'Informed Consent', 'Linear Models', 'Minors', 'Parental Consent', 'Parents', 'Surveys and Questionnaires', 'Videot... | 7,617,491 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E02.085', 'F04.047', 'I01.880.630.099'], ['F04.754.137'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['I01.880.604.583.427.134', 'N03.706.535.48... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agricultu... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
Analysis of the steady-state mechanism of the aminoacylation of tRNAPhe by phenylalanyl-tRNA synthetase from yeast. | The steady-state mechanism of the aminoacylation of tRNAPhe by the corresponding synthetase from yeast has been investigated in detail by kinetic experiments. It was found that there are two alternative mechanisms: one favoured at low tRNA concentrations and the other at high tRNA concentrations. ATP and Phe are bound ... | ['Amino Acyl-tRNA Synthetases', 'Kinetics', 'Phenylalanine', 'Phenylalanine-tRNA Ligase', 'RNA, Transfer', 'Saccharomyces cerevisiae'] | 353,737 | [['D08.811.464.263.200'], ['G01.374.661', 'G02.111.490'], ['D12.125.072.050.685', 'D12.125.142.666'], ['D08.811.464.263.200.650'], ['D13.444.735.757'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Defective stromal cell function in a mouse model of infusion-induced bone marrow failure. | OBJECTIVE: To study bone marrow (BM) stromal damage in a mouse model of infusion-induced BM failure.MATERIALS AND METHODS: Sublethally irradiated CByB6F1 mice were infused with 5 x 10(6) C57BL/6 (B6) lymph node (LN) cells. Recipient BM cells were taken at 3, 7, 10, and 14 days following LN infusion and were cultured in... | ['Animals', 'Bone Marrow', 'Bone Marrow Cells', 'Bone Marrow Diseases', 'Bystander Effect', 'Cells, Cultured', 'Hematopoiesis', 'Lymphocyte Transfusion', 'Lymphocytes', 'Mice', 'Spleen', 'Stromal Cells', 'Whole-Body Irradiation'] | 16,038,782 | [['B01.050'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['C15.378.190'], ['G04.085.155'], ['A11.251'], ['G04.152.825', 'G09.188.343'], ['E02.095.135.140.425.445'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['B01.050.150.900.649.313.992.635.505.500'], ['A10.549.700', 'A15.382.520.604.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stenting and the rate of pancreatic fistula following pancreaticoduodenectomy. | OBJECTIVE: To evaluate the efficacy of transanastomotic pancreatic duct internal stenting in the reduction of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy.DESIGN: Retrospective study.SETTING: Mayo Clinic.PATIENTS: Between January 1, 1999, and September 30, 2010, 553 patients underwent pancreati... | ['Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Fistula', 'Pancreaticoduodenectomy', 'Retrospective Studies', 'Stents'] | 22,250,109 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.267.775', 'C06.689.583', 'C23.300.575.185.775'], ['E04.210.760'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Graves' disease as immune reconstitution disease in HIV-positive patients is associated with naive and primary thymic emigrant CD4(+) T-cell recovery. | OBJECTIVE: Immune restoration disease (IRD) can develop in HIV-infected patients following antiretroviral therapy (ART) initiation as unmasking or paradoxical worsening of opportunistic infections and, rarely, autoimmune phenomena. Although IRD usually occurs in the first months of ART during memory CD4 T-cell recovery... | ['Adult', 'Anti-Retroviral Agents', 'Autoantibodies', 'CD4-Positive T-Lymphocytes', 'Case-Control Studies', 'Cytokines', 'Graves Disease', 'HIV Infections', 'Humans', 'Immune Reconstitution Inflammatory Syndrome', 'Immunophenotyping', 'Male', 'Middle Aged', 'Retrospective Studies'] | 23,939,238 | [['M01.060.116'], ['D27.505.954.122.388.077'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effects of continuous cropping on bacterial community diversity in rhizosphere soil of Rehmannia glutinosa]. | In this paper, T-RFLP (terminal restriction fragment length polymorphism) technique was adopted to study the dynamic changes of bacterial community in the rhizosphere soil of continuously cropped Rehmannia glutinosa L. The results showed that the Shannon diversity index, Margalef index, and similarity index of bacteria... | ['Agriculture', 'Bacteria', 'Biodiversity', 'Plant Roots', 'Rehmannia', 'Rhizosphere', 'Soil Microbiology'] | 21,361,008 | [['J01.040'], ['B03'], ['G16.500.275.157.049', 'N06.230.124.049'], ['A18.400'], ['B01.650.940.800.575.912.250.583.750'], ['G16.500.275.157.625', 'G16.500.853', 'N06.230.124.437'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages. | Glechoma hederacea (GH) is an herb widely used herb medicine for the treatment of a variety of pathologies. In this study, the effect of GH on interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS)-induced production of nitric oxide (NO), interleukin (IL)-12p70, IL-12p40, tumor necrosis factor-alpha (TNF-alpha), and... | ['Animals', 'Anti-Inflammatory Agents', 'Cell Survival', 'Cytokines', 'Dose-Response Relationship, Drug', 'Interferon-gamma', 'Lamiaceae', 'Lipopolysaccharides', 'Macrophages, Peritoneal', 'Mice', 'Nitric Oxide', 'Phytotherapy', 'Plant Extracts'] | 16,530,364 | [['B01.050'], ['D27.505.954.158'], ['G04.346'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['B01.650... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Third ventricle enlargement among newborn infants with trisomy 21. | OBJECTIVE: Our goal was to determine whether the third ventricle is significantly enlarged among neonates with trisomy 21, compared with infants without clinical signs of trisomy 21. This enlargement might be related to hypoplasia of the structures surrounding the third ventricle. These structures participate in cognit... | ['Cephalometry', 'Down Syndrome', 'Humans', 'Infant, Newborn', 'Third Ventricle', 'Ultrasonography'] | 16,651,295 | [['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A08.186.211.140.840'], ['E01.370.350.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Studies of endogenous polyphosphoinositide hydrolysis in human platelet membranes. Evidence that polyphosphoinositides remain inaccessible to phosphodiesterase in the native membrane. | Human platelet plasma membranes incubated in the presence of [gamma-32P]ATP and 15 mM MgCl2 incorporated radioactivity mostly into phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 4-phosphate (PIP), which represented together over 90% of the total lipid radioactivity. After washing, reincubation of... | ['Adenosine Triphosphate', 'Blood Platelets', 'Calcium', 'Cell Membrane', 'Deoxycholic Acid', 'Egtazic Acid', 'Humans', 'Hydrolysis', 'Magnesium', 'Phosphatidylinositol 4,5-Diphosphate', 'Phosphatidylinositol Phosphates', 'Phosphatidylinositols', 'Phosphoric Diester Hydrolases', 'Time Factors', 'Type C Phospholipases'] | 3,002,480 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.118.188', 'A15.145.229.188'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.149'], ['D04.210.500.105.225.272', 'D04.210.500.221.430.342'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['B01.050.150.900.649.31... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and biological properties of novel sphingosine derivatives. | Sphingosine-1-phosphate (S-1P) derivatives such as threo-(2S,3S)-analogues, which are C-3 stereoisomers of natural erythro-(2S,3R)-S-1P, have been synthesized starting from l-serine or (1S,2S)-2-amino-1-aryl-1,3-propanediols (6). threo-(1S,2R)-2-Amino-1-aryl-3-bromopropanols (HBr salt) have also been prepared from 6. T... | ['Calcium Signaling', 'HL-60 Cells', 'Humans', 'Lysophospholipids', 'Receptors, Lysosphingolipid', 'Sphingosine', 'Stereoisomerism', 'Structure-Activity Relationship'] | 15,686,924 | [['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.570.755.375.760.550'], ['D12.776.543.750.695.420.500'], ['D02.033.100.700', 'D02.033.455.843', 'D02.092.063.700'], ['G02.607.445.6... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The biphasic contrast method in the stomach examination. A comparative study with standard method and correlations with endoscopy (author's transl)]. | A two years-experience, using the biphasic contrast method in the evaluation of the stomach, is reported. Endoscopic and radiological results are compared. Our previous reports with standard contrast method are also reviewed. Ulcerative and neoplastic pathologies were studied and classified as proposed in the "trial po... | ['Contrast Media', 'False Negative Reactions', 'False Positive Reactions', 'Gastrectomy', 'Gastroscopy', 'Humans', 'Radiography', 'Stomach', 'Stomach Neoplasms', 'Stomach Ulcer'] | 7,232,780 | [['D27.505.259.500', 'D27.720.259'], ['E01.354.340'], ['E01.354.506'], ['E04.210.419'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['A03.556.875.875'], ['C04.588.274.476.767', 'C06.30... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differences in urinary prothrombin fragment 1 + 2 levels after total hip replacement in relation to venous thromboembolism and bleeding events. | BACKGROUND: Prothrombin fragment 1 + 2 is excreted in urine (uF1 + 2) as a result of thrombin generation and, therefore, may be a useful marker of coagulation status.OBJECTIVES: To assess uF1 + 2 levels after total hip replacement (THR) in patients with venous thromboembolism (VTE) and bleeding events.PATIENTS/METHODS:... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Biomarkers', 'Blood Coagulation', 'Female', 'Hemorrhage', 'Humans', 'Male', 'Middle Aged', 'Peptide Fragments', 'Postoperative Complications', 'Predictive Value of Tests', 'Prothrombin', 'Venous Thromboembolism'] | 18,680,542 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D23.101'], ['G09.188.390.150'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.644.541'], ['C23.550.767'], ['E05.318.370.800.650', 'N05.715.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
p65 Homodimer activity in distal airway cells determines lung dysfunction in equine heaves. | Nuclear factor-kappaB (NF-kappaB) activity, which is a key regulator of inflammatory gene expression, is increased in bronchial epithelial cells from horses suffering from heaves (a hypersensitivity-associated inflammatory condition of the lung). To determine whether this increased activity extends to distal airways an... | ['Animals', 'Base Sequence', 'Bronchoalveolar Lavage Fluid', 'DNA Probes', 'Dimerization', 'Horse Diseases', 'Horses', 'Hypersensitivity', 'Inflammation', 'NF-kappa B', 'Neutrophils', 'Respiratory Tract Diseases', 'Transcription Factor RelA'] | 11,457,483 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.927.100.500'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['G02.206', 'G03.230'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C20.543'], ['C23.550.470'], ['D05.500.672', 'D12.776.260.600', 'D12.776... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Inhibition of bacterial adherence to hydrocarbons and epithelial cells by emulsan. | Acinetobacter calcoaceticus RAG-1 and BD413, as well as Streptococcus pyogenes M-5, adhered to octane. Adherence was inhibited by emulsan (100 micrograms/ml), the polymeric emulsifying agent produced by A. calcoaceticus RAG-1. Emulsan also inhibited adherence of S. pyogenes and RAG-1 to buccal epithelial cells. The mea... | ['Acinetobacter', 'Cheek', 'Dose-Response Relationship, Drug', 'Epithelium', 'Humans', 'Mouth Mucosa', 'Octanes', 'Polysaccharides, Bacterial', 'Streptococcus pyogenes'] | 6,341,225 | [['B03.440.400.425.537.050', 'B03.660.250.530.050'], ['A01.456.505.173', 'A14.194'], ['G07.690.773.875', 'G07.690.936.500'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.615.550.599', 'A14.549.512'], ['D02.455.326.146.720'], ['D09.698.718', 'D23.050.161.616'], ['B03.353.750.737.872.575', 'B03.510... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells. | A recent analysis of gene expression in renal cell carcinoma cells led to the identification of mRNAs whose translation was dependent on the presence of the von Hippel-Lindau (VHL) tumor suppressor gene product, pVHL. Here, we investigate the finding that pVHL-expressing RCC cells (VHL(+)) exhibited elevated levels of ... | ["3' Untranslated Regions", 'Actins', 'Adenylate Kinase', 'Antigens, Surface', 'Base Sequence', 'Blotting, Northern', 'Blotting, Western', 'Carcinoma, Renal Cell', 'Cell Line, Tumor', 'Cytoplasm', 'DNA, Complementary', 'ELAV Proteins', 'ELAV-Like Protein 1', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Kidney N... | 14,517,280 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D08.811.913.696.650.025'], ['D23.050.301'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of various etching protocols on the flexural properties and surface topography of fiber-reinforced composite dental posts. | The purpose of this study was to evaluate the flexural properties and surface topography of fiber posts surface-treated with various etching protocols. Seventy each of three types of fiber posts: RelyX Fiber Post, Tenax Fiber Trans, and D.T. Light-Post Illusion X-Ro, were randomly divided into 7 groups: no surface trea... | ['Composite Resins', 'Dental Etching', 'Dental Stress Analysis', 'Glass', 'Hydrogen Peroxide', 'Materials Testing', 'Post and Core Technique', 'Surface Properties'] | 28,566,672 | [['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.931.475'], ['E06.308'], ['J01.637.437'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['E05.570'], ['E06.780.346.250.500', 'E07.695.190... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Sinusitis, current diagnostic and therapeutic possibilities]. | Important progress in the management of sinusitis has been made during the past decade. Diagnosis has been refined by the general use of endoscopic examinations of the nose and the CT scan. Knowledge of the pathophysiology of sinusitis has been improved by the systematic use of the examinations. As a consequence, the t... | ['Endoscopy', 'Humans', 'Microsurgery', 'Nasal Cavity', 'Postoperative Care', 'Sinusitis', 'Tomography, X-Ray Computed'] | 7,502,250 | [['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.494', 'E05.591.580'], ['A04.531.449'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['C01.748.749', 'C08.460.692.752', 'C08.730.749', 'C09.603.692.752'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Annexin A1 modulates natural and glucocorticoid-induced resolution of inflammation by enhancing neutrophil apoptosis. | This study aimed at assessing whether AnxA1, a downstream mediator for the anti-inflammatory effects of GCs, could affect the fate of immune cells in tissue exudates, using LPS-induced pleurisy in BALB/c mice. AnxA1 protein expression in exudates was increased during natural resolution, as seen at 48-72 h post-LPS, an ... | ['Acute Disease', 'Animals', 'Annexin A1', 'Apoptosis', 'Dexamethasone', 'Disease Models, Animal', 'Glucocorticoids', 'Inflammation', 'Inflammation Mediators', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Neutrophils', 'Up-Regulation'] | 22,493,082 | [['C23.550.291.125'], ['B01.050'], ['D12.776.157.125.050.050'], ['G04.146.954.035'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['C23.550.470'], ['D23.469'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Levetiracetam inhibits neurotransmitter release associated with CICR. | To define the antiepileptic mechanisms of levetiracetam (LEV), the present study determined the concentration-dependent effects of locally perfused LEV on the releases of norepinephrine, dopamine, serotonin, l-glutamate and GABA induced by 50 mMK(+)-evoked stimulation and agonists of ryanodine receptor (RyR) and inosit... | ['Animals', 'Anticonvulsants', 'Chromatography, High Pressure Liquid', 'Inositol 1,4,5-Trisphosphate Receptors', 'Levetiracetam', 'Male', 'Microdialysis', 'Neurotransmitter Agents', 'Piracetam', 'Prefrontal Cortex', 'Rats', 'Rats, Sprague-Dawley', 'Ryanodine Receptor Calcium Release Channel', 'Synaptic Transmission'] | 22,484,014 | [['B01.050'], ['D27.505.954.427.080'], ['E05.196.181.400.300'], ['D12.776.157.530.400.150.760', 'D12.776.543.550.450.150.760', 'D12.776.543.585.400.150.760', 'D12.776.826.179'], ['D02.065.064.432', 'D02.241.081.018.110.463', 'D03.383.773.812.362'], ['E05.196.353.500'], ['D27.505.519.625', 'D27.505.696.577'], ['D02.065.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Life-saving percutaneous mitral valvuloplasty on a pregnant woman with refractory cardiogenic shock. | Pregnancy increases body blood volume and cardiac output. These changes can exacerbate mitral stenosis symptoms. Symptomatic mitral stenosis during pregnancy has been successfully treated with percutaneous mitral valvuloplasty (PMV). We present the case of a 35-year-old white female who developed cardiogenic shock due ... | ['Adult', 'Catheterization', 'Female', 'Humans', 'Mitral Valve Stenosis', 'Pregnancy', 'Pregnancy Complications, Cardiovascular', 'Shock, Cardiogenic'] | 18,514,026 | [['M01.060.116'], ['E02.148', 'E05.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.484.517'], ['G08.686.784.769'], ['C13.703.634', 'C14.583'], ['C14.280.647.500.750', 'C14.907.585.500.750', 'C23.550.513.355.750.750', 'C23.550.717.489.750.750', 'C23.550.835.550']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adhesion of memory lymphocytes to vascular cell adhesion molecule-1-transduced human vascular endothelial cells under simulated physiological flow conditions in vitro. | The accumulation of mononuclear leukocytes is an early and persistent finding in atherosclerotic plaques. These mononuclear leukocytes are mostly monocyte-derived, but up to 20% are lymphocytes, predominantly CD4+ CD45RO+ (memory) T cells. To evaluate the potential of adenovirus vectors for studies of mononuclear leuko... | ['Adenoviridae', 'Animals', 'Cell Adhesion', 'Cells, Cultured', 'E-Selectin', 'Endothelium, Vascular', 'Gene Transfer Techniques', 'Humans', 'Intercellular Adhesion Molecule-1', 'Jurkat Cells', 'Rabbits', 'T-Lymphocytes', 'Vascular Cell Adhesion Molecule-1'] | 8,943,959 | [['B04.280.030'], ['B01.050'], ['G04.022'], ['A11.251'], ['D12.776.395.550.200.700.300', 'D12.776.503.843.300', 'D12.776.543.550.200.700.300', 'D23.050.301.350.700.300'], ['A07.015.700.500', 'A10.272.491.355'], ['E05.393.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.200.450', 'D12.776.543.55... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancement of BALB/c 3T3 cells transformation by 1,2-dibromoethane promoting effect. | Two of the most representative halogenated aliphatic hydrocarbons, 1,2-dibromoethane and 1,1,2,2-tetrachloroethane, were tested in the two-stage cell transformation model for analysing the promoting ability. Both of these compounds had previously been found to exert genotoxic effects, probably acting as moderate initia... | ['3T3 Cells', 'Animals', 'Carcinogens', 'Cell Transformation, Neoplastic', 'Dose-Response Relationship, Drug', 'Ethane', 'Ethylene Dibromide', 'Hydrocarbons, Chlorinated', 'Methylnitronitrosoguanidine', 'Mice', 'Tetradecanoylphorbol Acetate'] | 8,625,443 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['D27.888.569.100'], ['C04.697.098.500', 'C23.550.727.098.500'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.326.146.379'], ['D02.455.526.368.225'], ['D02.455.526.439'], ['D02.078.370.649.400', 'D02.654.567.400'], ['B01.050.150.900.649.313.992.635.505.500'], [... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing binocular interaction in amblyopia and its clinical feasibility. | PURPOSE: To measure binocular interaction in amblyopes using a rapid and patient-friendly computer-based method, and to test the feasibility of the assessment in the clinic.METHODS: Binocular interaction was assessed in subjects with strabismic amblyopia (n = 7), anisometropic amblyopia (n = 6), strabismus without ambl... | ['Adolescent', 'Adult', 'Amblyopia', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Reproducibility of Results', 'Vision Tests', 'Vision, Binocular', 'Visual Acuity', 'Young Adult'] | 24,959,842 | [['M01.060.057'], ['M01.060.116'], ['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Early versus delayed rebonding of orthodontic brackets. | OBJECTIVES: There are controversial reports regarding the effect of repeated bonding on shear bond strength (SBS) of orthodontic attachments. The aim of this study was to evaluate the SBS of brackets following early and delayed rebonding, and after employing different methods of composite removal.MATERIALS AND METHODS:... | ['Acid Etching, Dental', 'Adhesiveness', 'Bicuspid', 'Dental Bonding', 'Dental Debonding', 'Dental Enamel', 'Dental Prophylaxis', 'Humans', 'Materials Testing', 'Microscopy, Electron, Scanning', 'Orthodontic Brackets', 'Phosphoric Acids', 'Resin Cements', 'Rubber', 'Saliva, Artificial', 'Shear Strength', 'Stress, Mecha... | 22,583,583 | [['E06.931.475.111'], ['G02.860.139'], ['A14.549.167.860.150'], ['E06.095'], ['E06.178'], ['A14.549.167.900.255'], ['E06.721.189', 'E06.761.227'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E06.658.453.255.500'], ['D01.029.260.700.675', 'D01.695.625.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Gene therapy for meningioma: improved gene delivery with targeted adenoviruses. | OBJECT: Due to their surgical inaccessibility or aggressive behavior, some meningiomas cannot be cured with current treatment strategies. Gene therapy is an emerging strategy for the treatment of brain tumors, which the authors investigated to determine whether adenoviruses could be used for gene transfer in meningioma... | ['Adenoviridae', 'Adult', 'Aged', 'Gene Targeting', 'Gene Transfer Techniques', 'Genetic Therapy', 'Genetic Vectors', 'Humans', 'In Vitro Techniques', 'Meningeal Neoplasms', 'Meningioma', 'Middle Aged', 'Spheroids, Cellular', 'Tumor Cells, Cultured'] | 12,186,474 | [['B04.280.030'], ['M01.060.116'], ['M01.060.116.100'], ['E05.393.335'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.557.580.520', 'C04.557.645.520', 'C04.588.614.250.580.500', 'C10.... | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Renal denervation by CT-guided periarterial injection of hyperosmolar saline, vincristine, paclitaxel and guanethidine in a pig model. | AIMS: The aim of the study was to evaluate the feasibility, safety and efficacy of renal sympathetic denervation with CT-guided periarterial injection of potentially neurolytic agents in pigs.METHODS AND RESULTS: Unilateral injection of formulations containing either 5M hyperosmolar saline, vincristine, paclitaxel or g... | ['Animals', 'Blood Pressure', 'Guanethidine', 'Kidney', 'Norepinephrine', 'Paclitaxel', 'Swine', 'Sympathectomy', 'Tomography, X-Ray Computed', 'Vincristine'] | 27,890,860 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.078.370.460'], ['A05.810.453'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['D02.455.426.392.368.242.888.777', 'D02.455.849.291.850.777'], ['B01.050.150.900.649.313.500.880']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. | Loss-of-function mutations in CDKL5 kinase cause severe neurodevelopmental delay and early-onset seizures. Identification of CDKL5 substrates is key to understanding its function. Using chemical genetics, we found that CDKL5 phosphorylates three microtubule-associated proteins: MAP1S, EB2 and ARHGEF2, and determined th... | ['Animals', 'Dendrites', 'Epileptic Syndromes', 'Mice', 'Mice, Knockout', 'Microtubule-Associated Proteins', 'Microtubules', 'Phosphorylation', 'Protein-Serine-Threonine Kinases', 'Rho Guanine Nucleotide Exchange Factors', 'Spasms, Infantile'] | 30,266,824 | [['B01.050'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['C10.228.140.490.493'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['D12.776.220.600.450', 'D12.776.631.560'], ['A11.284.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a rapid and sensitive LC-ESI/MS/MS assay for the quantification of propofol using a simple off-line dansyl chloride derivatization reaction to enhance signal intensity. | A rapid, selective and sensitive method was developed for the determination of propofol concentration using an off-line dansyl chloride derivatization step to enhance signal intensity. The method consisted of a protein precipitation extraction followed by derivatization with dansyl chloride and analysis by liquid chrom... | ['Animals', 'Calibration', 'Chromatography', 'Chromatography, High Pressure Liquid', 'Chromatography, Liquid', 'Dansyl Compounds', 'Free Radical Scavengers', 'Male', 'Mass Spectrometry', 'Models, Chemical', 'Propofol', 'Rats', 'Rats, Inbred F344', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectromet... | 15,963,676 | [['B01.050'], ['E05.978.155'], ['E05.196.181'], ['E05.196.181.400.300'], ['E05.196.181.400'], ['D02.455.426.559.847.638.204', 'D02.886.590.192', 'D04.615.638.204'], ['D27.505.519.217.500'], ['E05.196.566'], ['E05.599.495'], ['D02.455.426.559.389.657.773'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Discrimination of symmetric time-intensity traded binaural stimuli. | Experiments were conducted to determine the extent to which listeners can discriminate between different combinations of interaural time and intensity for binaural stimulus configurations which eliminate loudness, lateralization, and image-diffuseness cues. A two-interval forced choice paradigm was used, and the task o... | ['Acoustic Stimulation', 'Auditory Perception', 'Humans'] | 521,558 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of esophageal pressure with pulse transit time as a measure of respiratory effort for scoring obstructive nonapneic respiratory events. | Obstructive nonapneic respiratory events (ONAREs) are much more difficult to detect and classify than apneas unless sensitive measures of respiratory effort and airflow are employed. The aim of this study was to compare two measures of respiratory effort, esophageal pressure monitoring (Pes) and pulse transit time (PTT... | ['Esophagus', 'Humans', 'Lung Diseases, Obstructive', 'Male', 'Middle Aged', 'Observer Variation', 'Pressure', 'Prospective Studies', 'Pulse', 'Sensitivity and Specificity', 'Time Factors'] | 10,903,225 | [['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['G01.374.715'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.370.370.380.650... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1á-Fndc5 pathway in muscle. | Myostatin (Mstn) is predominantly expressed in skeletal muscles and plays important roles in regulating muscle growth and development, as well as fat deposition. Mstn-knockout (Mstn(-/-)) mice exhibit increased muscle mass due to both hypertrophy and hyperplasia, and leaner body composition due to reduced fat mass. Her... | ['Adenylate Kinase', 'Adipose Tissue, Brown', 'Adipose Tissue, White', 'Animals', 'Fibronectins', 'Mice', 'Mice, Knockout', 'Muscle, Skeletal', 'Myostatin', 'Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha', 'Trans-Activators', 'Transcription Factors', 'Up-Regulation'] | 23,362,117 | [['D08.811.913.696.650.025'], ['A10.165.114.322'], ['A10.165.114.830'], ['B01.050'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Low-intensity laser irradiation stimulates wound healing in diabetic wounded fibroblast cells (WS1). | BACKGROUND: Patients with diabetes suffer from slow-to-heal wounds, which often necessitate amputation. Low-intensity laser irradiation (LILI) has been shown to reduce the healing time in such patients. This study aimed to determine the effect of different wavelengths of LILI on cellular migration, viability, and proli... | ['Cell Growth Processes', 'Cell Movement', 'Cell Survival', 'Diabetes Mellitus', 'Fibroblast Growth Factor 2', 'Fibroblasts', 'Humans', 'Low-Level Light Therapy', 'Wound Healing', 'Wounds and Injuries'] | 21,128,844 | [['G04.161', 'G07.345.249.410'], ['G04.198', 'G07.568.500.180'], ['G04.346'], ['C18.452.394.750', 'C19.246'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594.540', 'E02.774.500'], ['G16.762.891'], ['C26']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions of colipase with bile salt micelles. 2. Study by dialysis and spectrophotometry. | The finding reported in the preceding paper that colipase is able to bind one sodium taurodeoxycholate micelle per molecule was confirmed by dialysis and spectrophotometry. Dialysis in the presence of labelled sodium taurodeoxycholate provided a direct qualitative proof of taurodeoxycholate binding to colipase. This bi... | ['Binding Sites', 'Colipases', 'Deoxycholic Acid', 'Dialysis', 'Micelles', 'Proteins', 'Spectrophotometry'] | 1,183,450 | [['G02.111.570.120'], ['D12.776.200'], ['D04.210.500.105.225.272', 'D04.210.500.221.430.342'], ['E05.196.353', 'G02.186'], ['D05.374', 'D26.255.560'], ['D12.776'], ['E05.196.712.726', 'E05.196.867.826']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimation of viscous dissipative stresses induced by a mechanical heart valve using PIV data. | Among the clinical complications of mechanical heart valves (MHVs), hemolysis was previously thought to result from Reynolds stresses in turbulent flows. A more recent hypothesis suggests viscous dissipative stresses at spatial scales similar in size to red blood cells may be related to hemolysis in MHVs, but the resol... | ['Aortic Valve', 'Blood Flow Velocity', 'Computer Simulation', 'Elastic Modulus', 'Energy Transfer', 'Heart Valve Prosthesis', 'Models, Cardiovascular', 'Shear Strength', 'Stress, Mechanical', 'Viscosity'] | 20,020,213 | [['A07.541.510.110'], ['E01.370.370.130', 'G09.330.380.630.080'], ['L01.224.160'], ['G01.374.590.605'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['E07.695.310'], ['E05.599.395.161'], ['G01.374.820'], ['G01.374.835'], ['G02.930']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Electrostatic state of the cytoplasmic domain influences inactivation at the selectivity filter of the KcsA potassium channel. | KcsA is a proton-activated K+ channel that is regulated at two gates: an activation gate located in the inner entrance of the pore and an inactivation gate at the selectivity filter. Previously, we revealed that the cytoplasmic domain (CPD) of KcsA senses proton and that electrostatic changes of the CPD influences the ... | ['Bacterial Proteins', 'Cytoplasm', 'Escherichia coli', 'Escherichia coli Proteins', 'Hydrogen-Ion Concentration', 'Ion Channel Gating', 'Ions', 'Lipids', 'Liposomes', 'Mutation', 'Potassium', 'Potassium Channels', 'Protein Domains', 'Static Electricity'] | 30,053,405 | [['D12.776.097'], ['A11.284.430.214'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G02.300'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['D01.248.497'], ['D10'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['G05.365.590'], ['D01.268.549.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
New mutation of the myelin P0 gene in a pedigree of Charcot-Marie-Tooth neuropathy 1. | P0, the major structural protein of peripheral myelin, is a homophilic adhesion molecule with a single immunoglobulin (Ig) domain, which contains a single N-linked glycosylation site and two cysteines. We have previously reported four different mutations of the myelin P0 gene in four families of Charcot-Marie-Tooth neu... | ['Adolescent', 'Amino Acid Sequence', 'Base Sequence', 'Cell Adhesion Molecules, Neuronal', 'Charcot-Marie-Tooth Disease', 'Female', 'Humans', 'Molecular Sequence Data', 'Mutation', 'Myelin P0 Protein', 'Myelin Proteins', 'Polymerase Chain Reaction'] | 7,505,151 | [['M01.060.057'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.395.550.200.250', 'D12.776.543.550.200.250', 'D23.050.301.350.250'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['B... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Deficits of facial emotion recognition and visual information processing in adult patients with classical galactosemia. | BACKGROUND: Classical galactosemia (CG) is due to a severe deficiency of the galactose-1-phosphate uridyl-transferase (GALT), the main enzyme of galactose metabolism. Even early introduction of galactose-restricted diet fails to prevent long-term complications, including cognitive impairment, neurological and psychiatr... | ['Adult', 'Cognitive Dysfunction', 'Cohort Studies', 'Facial Recognition', 'Female', 'Galactosemias', 'Humans', 'Male', 'Neuropsychological Tests', 'Switzerland', 'Visual Perception'] | 30,808,388 | [['M01.060.116'], ['F03.615.250.700'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['F02.463.593.524.250.500', 'F02.463.593.524.500.500', 'F02.463.593.932.622.500'], ['C10.228.140.163.100.320', 'C16.320.565.189.320', 'C16.320.565.202.355', 'C18.452.132.100.320', 'C18.452.648.189.320',... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Economic aspects of medical errors. | The critical problem of medical errors and the associated costs has recently been increasingly in the focus of attention of a number of world renowned experts. In the present article we review in detail and analyse the economic aspects of this problem. A methodology to assess the cost of medical errors and an algorithm... | ['Cost-Benefit Analysis', 'Costs and Cost Analysis', 'Humans', 'Medical Errors'] | 22,908,832 | [['N03.219.151.125'], ['N03.219.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.450']] | ['Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Online signature verification with support vector machines based on LCSS kernel functions. | In this paper, a new technique for online signature verification or identification is proposed. The technique integrates a longest common subsequences (LCSS) detection algorithm which measures the similarity of signature time series into a kernel function for support vector machines (SVM). LCSS offers the possibility t... | ['Algorithms', 'Biometry', 'Electronic Data Processing', 'Handwriting', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Information Storage and Retrieval', 'Pattern Recognition, Automated', 'Reading'] | 19,906,588 | [['G17.035', 'L01.224.050'], ['E05.318.740.225', 'N06.850.505.200'], ['L01.224.085'], ['L01.559.423.906.539'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.313.500.750.280', 'L01.470'], ['L01.399.750'], ['L01.559.423.557']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Who's got what? A benchmarking exercise for tertiary neonatal units. | OBJECTIVES: To determine the current facilities available in level-3 neonatal units (NNU) in Australia and New Zealand to assist with establishment of standards for new NNU design.BACKGROUND: Many current NNU in Australia and New Zealand are planning new or redesigning existing facilities. There are no adequate local s... | ['Australia', 'Benchmarking', 'Environment, Controlled', 'Health Facility Environment', 'Hospital Design and Construction', 'Intensive Care Units, Neonatal', 'New Zealand', 'Surveys and Questionnaires'] | 16,398,866 | [['Z01.639.100', 'Z01.678.100.373'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['N06.230.150'], ['N02.278.220', 'N05.300.430.400'], ['J01.086.339.250', 'N02.278.200.403'], ['N02.278.388.493.390.380'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E05.318.308.980', 'N05... | ['Geographicals [Z]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Diclofenac but not celecoxib improves endothelial function in rheumatoid arthritis: A study in adjuvant-induced arthritis. | BACKGROUND AND AIMS: We aimed at investigating the effect of celecoxib (COX-2 selective inhibitor) and diclofenac (non-selective COX inhibitor) on endothelial function, and at identifying the underlying mechanisms in adjuvant-induced arthritis (AIA).METHODS: At the first signs of AIA, diclofenac (5 mg/kg twice a day, i... | ['Animals', 'Aorta, Thoracic', 'Arginase', 'Arginine', 'Arthritis, Experimental', 'Biological Factors', 'Blood Pressure', 'Celecoxib', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Cyclooxygenase Inhibitors', 'Diclofenac', 'Dose-Response Relationship, Drug', 'Endothelium, Vascular', "Freund's Adjuvant", 'In Vitro... | 29,024,866 | [['B01.050'], ['A07.015.114.056.372'], ['D08.811.277.913.292'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['C05.550.114.015', 'E05.598.500.249'], ['D23'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['D08.811.600.720.750'], ['D27.505.51... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optical Screening for Rapid Antimicrobial Susceptibility Testing and for Observation of Phenotypic Diversity among Strains of the Genetically Clonal Species Bacillus anthracis. | During high-impact events involving Bacillus anthracis, such as the Amerithrax incident of 2001 or the anthrax outbreaks in Russia and Sweden in 2016, critical decisions to reduce morbidity and mortality include rapid selection and distribution of effective antimicrobial agents for treatment and postexposure prophylaxi... | ['Anti-Bacterial Agents', 'Automation, Laboratory', 'Bacillus anthracis', 'Ciprofloxacin', 'Doxycycline', 'Genotype', 'Microbial Sensitivity Tests', 'Microscopy', 'Penicillins', 'Time Factors', 'Time-Lapse Imaging'] | 28,053,211 | [['D27.505.954.122.085'], ['E05.064', 'J01.897.104.416'], ['B03.300.390.400.158.218.151', 'B03.353.500.100.218.151', 'B03.510.100.100.218.151', 'B03.510.415.400.158.218.151', 'B03.510.460.410.158.218.151'], ['D03.633.100.810.835.322.186'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['G05.380'], ['E01.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Modulation of macrophage functions by sheeppox virus provides clues to understand interaction of the virus with host immune system. | BACKGROUND: Poxviruses encode a range of immunomodulatory genes to subvert or evade the challenges posed by the innate and adaptive immune responses. However, the inactivated poxviruses possessed immunostimulating capacity and were used as a prophylactic or metaphylactic application that efficiently reduced susceptibil... | ['Animals', 'Capripoxvirus', 'Cell Proliferation', 'Cells, Cultured', 'Interleukin-10', 'Interleukin-12', 'Macrophages, Peritoneal', 'Male', 'Mice', 'Phytohemagglutinins', 'Poxviridae Infections', 'Spleen', 'Superoxide Dismutase', 'T-Lymphocytes'] | 15,784,144 | [['B01.050'], ['B04.280.650.160.150'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['D12.644.276.374.465.512', 'D12.776.467.374.465.512', 'D23.529.374.465.512'], ['A11.329.372.630', 'A11.627.482.630', 'A11.733.397.630', 'A15.382.670... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simultaneous determination of free and total paclitaxel in blood in a three-phase laminar flow microchip. | In this study, a three-phase laminar flow microfluidic chip (TPL chip) combined with HPLC was developed for monitoring free and total concentrations of paclitaxel (PTX) in blood simultaneously. A diluted whole blood sample (aqueous phase) was introduced into the chip, ethyl acetate (organic phase) was introduced into t... | ['Animals', 'Chromatography, High Pressure Liquid', 'Humans', 'Microfluidics', 'Paclitaxel', 'Rats', 'Reproducibility of Results', 'Rheology', 'Serum Albumin, Human'] | 32,823,097 | [['B01.050'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['D02.455.426.392.368.242.888.777', 'D02.455.849.291.850.777'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Molecular cloning of the gene encoding the putative polymerase of mouse hepatitis coronavirus, strain A59. | Complementary DNA (cDNA) libraries were constructed representing the genome RNA of the coronavirus mouse hepatitis virus, strain A59 (MHV-A59). From these libraries clones were selected to form a linear map across the entire gene A, the putative viral polymerase gene. This gene is approximately 23 kb in length, conside... | ['Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'DNA-Directed RNA Polymerases', 'Genes', 'Genes, Viral', 'Hydrogen Bonding', 'Molecular Sequence Data', 'Murine hepatitis virus', 'Nucleic Acid Conformation', 'RNA, Viral', 'Restriction Mapping'] | 2,545,027 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D08.811.913.696.445.735.270'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['G02.282'], ['L01.453.245.667'], ['B04.450.580', 'B04... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cytokine response to group B streptococcus infection in mice. | This study was undertaken to better understand the complex relationship between specific and non-specific host defence mechanisms and group B streptococci (GBS). A comprehensive kinetics analysis of cytokine mRNA expression was performed, by Northern blot assay, in peritoneal exudate cells (PEC) and spleen cells (SC) r... | ['Animals', 'Cytokines', 'Female', 'Gene Expression', 'Injections, Intraperitoneal', 'Killer Cells, Natural', 'Macrophages, Peritoneal', 'Male', 'Mice', 'Spleen', 'Streptococcal Infections', 'Streptococcus agalactiae'] | 9,600,312 | [['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.297'], ['E02.319.267.530.490'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['A11.329.372.630', 'A11.627.482.630', 'A11.733.397.630', 'A15.382.670.522.630', 'A15.382.680.397.630'], ['B01.050.150.900.649... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis of quaternary carbon stereogenic centers through enantioselective Cu-catalyzed allylic substitutions with vinylaluminum reagents. | Catalytic enantioselective allylic substitution (EAS) reactions, which involve the use of alkyl- or aryl-substituted vinylaluminum reagents and afford 1,4-dienes containing a quaternary carbon stereogenic center at their C-3 site, are disclosed. The C-C bond-forming transformations are promoted by 0.5-2.5 mol % of sulf... | ['Allyl Compounds', 'Aluminum', 'Carbon', 'Catalysis', 'Copper', 'Indicators and Reagents', 'Stereoisomerism'] | 20,860,365 | [['D02.455.326.271.122'], ['D01.268.557.050', 'D01.552.547.050'], ['D01.268.150'], ['G02.130'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D27.720.470.410'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Study on the effects of heat on blood and on the post-mortem estimation of carboxyhaemoglobin and methaemoglobin. | Blood samples of different carboxyhaemoglobin (CoHb) content (0%, 50%, 100%) were analysed, after short exposure to heat, for determination of the change of CoHb and methaemoglobin (MetHb) during the succeeding 14 days. Untreated blood showed an initial increase of MetHb after heating followed by a decrease during this... | ['Burns', 'Carboxyhemoglobin', 'Cause of Death', 'Humans', 'Methemoglobin', 'Spectrophotometry'] | 2,925,132 | [['C26.200'], ['D12.776.124.400.141', 'D12.776.422.316.762.149'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.400.599', 'D12.776.422.316.762.571'], ['E05.196.712.726', 'E05.196.867.826']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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