Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Differential fibrinolytic properties of the recombinant plasminogen activator BM 06.022 in human plasma and blood clot systems in vitro. | The effects of the unglycosylated recombinant plasminogen activator BM 06.022, consisting of the kringle 2 and protease domains of tissue-type plasminogen activator (t-PA), on clot lysis were evaluated in an in vitro system. Fresh and aged 125I-labelled human platelet-poor (PPP) and platelet-rich plasma (PRP) and whole... | ['Evaluation Studies as Topic', 'Fibrinolysis', 'Humans', 'In Vitro Techniques', 'Peptide Fragments', 'Plasma', 'Plasminogen Activators', 'Recombinant Proteins', 'Tissue Plasminogen Activator', 'Urokinase-Type Plasminogen Activator'] | 8,388,740 | [['E05.337', 'N05.715.360.335'], ['G09.188.390.150.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.644.541'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['D08.811.277.656.300.760.635', 'D08.811.277.656.959.350.635', 'D12.776.124.125.662'], ['D12.776.828'], ['D08.811.277.656.300.76... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Principal role of IL-12p40 in the decreased Th1 and Th17 responses driven by dendritic cells of mice lacking IL-12 and IL-18. | IL-12 and IL-18 are cytokines which are mainly secreted by endothelial cells and monocytes including dendritic cells. The well-known effects of IL-12 and IL-18 in the protection against bacteria and virus infection as well as tumor development are associated with their characteristics in synergistically driving the dev... | ['Animals', 'Cell Differentiation', 'Cell Polarity', 'Cell Proliferation', 'Dendritic Cells', 'Female', 'Histocompatibility Antigens Class II', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-12 Subunit p40', 'Interleukin-17', 'Interleukin-18', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout',... | 23,697,689 | [['B01.050'], ['G04.152'], ['G04.250'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Paradoxical embolism through a patent foramen ovale. 4 cases]. | Four cases of paradoxical embolism through a patent foramen ovale associated with massive pulmonary embolism are reported. In two cases, patency of the foramen ovale was demonstrated by a new technique: cross-sectional contrast echocardiography potentiated by coughing. The conventional surgical treatment included arter... | ['Echocardiography', 'Embolism', 'Female', 'Heart Septal Defects, Atrial', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Embolism', 'Recurrence'] | 6,226,989 | [['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.907.355.350'], ['C14.240.400.560.375', 'C14.280.400.560.375', 'C16.131.240.400.560.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C08.381.746', 'C14.907.355.350.700'], ['C23.550.291.937']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Measuring and mapping disparities in access to fresh fruits and vegetables in Montr?al. | OBJECTIVE: This study was conducted to evaluate disparities in access to healthy food in Montreal, focusing on the availability of fresh fruits and vegetables (F/V) as an indicator.METHOD: F/V selling area was measured in all food retail stores and public markets offering more than 75 square feet of fresh fruits and ve... | ['Food Supply', 'Fruit', 'Health Status Disparities', 'Humans', 'Linear Models', 'Nutritional Status', 'Poverty', 'Quebec', 'Socioeconomic Factors', 'Vegetables'] | 18,435,382 | [['J01.576.423.750'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.52... | ['Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Cannabidiol promotes browning in 3T3-L1 adipocytes. | Recruitment of the brown-like phenotype in white adipocytes (browning) and activation of existing brown adipocytes are currently being investigated as a means to combat obesity. Thus, a wide variety of dietary agents that contribute to browning of white adipocytes have been identified. The present study was designed to... | ['3T3-L1 Cells', 'Adipocytes', 'Animals', 'Antigens, Differentiation', 'Cannabidiol', 'Gene Expression Regulation', 'Lipogenesis', 'Lipolysis', 'Mice', 'Thermogenesis'] | 27,067,870 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['D02.455.849.090.100'], ['G05.308'], ['G02.111.528', 'G03.458.249'], ['G02.111.534', 'G03.458.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['G07.110.232.778', 'G07.410.421.778', 'G16.012.50... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Haltere afferents provide direct, electrotonic input to a steering motor neuron in the blowfly, Calliphora. | The first basalar muscle (b1) is one of 17 small muscles in flies that control changes in wing stroke kinematics during steering maneuvers. The b1 is unique, however, in that it fires a single phase-locked spike during each wingbeat cycle. The phaselocked firing of the b1's motor neuron (mnb1) is thought to result from... | ['Afferent Pathways', 'Animals', 'Diptera', 'Electrophysiology', 'Flight, Animal', 'Mechanoreceptors', 'Motor Neurons', 'Neurons, Afferent', 'Reflex', 'Synapses'] | 8,756,451 | [['A08.612.220'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750'], ['H01.158.344.528', 'H01.158.782.236'], ['G11.427.410.568.304', 'G11.427.410.698.416'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['A08.675.655.500', 'A11.671.655.500'], ['A08.675.650', 'A11.671.650'], ['E01.370.376.550.650... | ['Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of protracted mild hyperthermia on polymerase activity in a human melanoma cell line. | Radioresistant human melanoma SkMel-3 was evaluated with its sensitivity to thermal cell killing and polymerase inactivation. Cells were heated from 40 to 45 degrees C and demonstrated no thermal tolerance development for any of the temperatures tested. In addition, at 45 degrees C the heat survival curve showed a larg... | ['Cell Survival', 'DNA Polymerase I', 'DNA Polymerase II', 'DNA Polymerase III', 'Humans', 'Hyperthermia, Induced', 'Melanoma', 'Nucleic Acid Synthesis Inhibitors', 'Radiation Tolerance', 'Temperature', 'Time Factors', 'Tumor Cells, Cultured'] | 7,884,242 | [['G04.346'], ['D08.811.913.696.445.308.300.225'], ['D08.811.913.696.445.308.300.230'], ['D08.811.913.696.445.308.300.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['D27.505.519.389.675'], ['G04.712', 'G07.738'], ['G01.906... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Changes in the indices of the coronary amd myocardial reserves in myocardial infarct patients during rehabilitation]. | The article analyses the results of the complex examination of 52 patients with large-focal and through-and-through myocardial infarction using veloergometry, echocardiography, tetrapolar rheography, diurnal ECG monitoring at cardioanalyzer. It was found out that veloergometry was more preferable in the late hospital p... | ['Adult', 'Coronary Vessels', 'Heart', 'Heart Function Tests', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Time Factors'] | 1,481,425 | [['M01.060.116'], ['A07.015.114.269', 'A07.015.908.194'], ['A07.541'], ['E01.370.370.380'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['G01.910.857']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Narcolepsy following cerebral hypoxic ischemia. | A 51-year-old man with non-HLA-DR2 histocompatibility developed classic signs and symptoms of the narcoleptic tetrad soon after recovering from an episode of cardiopulmonary insufficiency, which occurred during induction of surgical anesthesia. Symptoms included excessive daytime sleepiness, hypnagogic hallucinations, ... | ['Anesthesia, Intravenous', 'Brain Ischemia', 'Cerebral Infarction', 'Humans', 'Hypoxia, Brain', 'Male', 'Middle Aged', 'Narcolepsy', 'Pentobarbital', 'Pons', 'Raphe Nuclei'] | 3,717,910 | [['E03.155.308'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.624', 'C23.888.852.079.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Understanding a Nonlinear Causal Relationship Between Rewards and Physicians' Contributions in Online Health Care Communities: Longitudinal Study. | BACKGROUND: The online health care community is not just a place for the public to share physician reviews or medical knowledge, but also a physician-patient communication platform. The medical resources of developing countries are relatively inadequate, and the online health care community is a potential solution to a... | ['Communication', 'Community Health Services', 'Education, Distance', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Nonlinear Dynamics', 'Physicians', 'Reward'] | 29,269,344 | [['F01.145.209', 'L01.143'], ['N02.421.143'], ['I02.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E05.599.850', 'H01.548.675'], ['M01.526.485.810', 'N02.360.810'], ['F02.463.425.770.836']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Involvement of Clp protease activity in modulating the Bacillus subtilissigmaw stress response. | The induction of Bacillus subtilis genes controlled by the extracytoplasmic function alternative sigma factor sigmaW is strongly impaired in a strain deleted for the ClpP peptidase gene and in a double knockout of the ClpX and ClpE ATPase genes. Truncated soluble forms of the sigmaW anti-sigma factor RsiW are stabilize... | ['Adenosine Triphosphatases', 'Alanine', 'Alkalies', 'Amino Acid Sequence', 'Bacillus subtilis', 'Bacterial Proteins', 'Cell Membrane', 'Conserved Sequence', 'Endopeptidase Clp', 'Gene Expression Regulation, Bacterial', 'Genes, Reporter', 'Molecular Sequence Data', 'Protein Structure, Tertiary', 'Regulon', 'Sigma Facto... | 16,899,079 | [['D08.811.277.040.025'], ['D12.125.042'], ['D01.045'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['A11.284.149'], ['G02.111.570.580'], ['D08.811.277.04... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Voxel-based Histographic Analysis of the Basilar Artery in Patients with Isolated Pontine Infarction. | BACKGROUND AND PURPOSE: The signal information per voxels of magnetic resonance imaging (MRI) for vessel wall could reflect the pathologic features of atherosclerotic vessels. The aim of this study is to evaluate the usefulness of magnetic resonance voxel-based histogram (VBH) of atherosclerotic basilar artery in patie... | ['Aged', 'Aged, 80 and over', 'Basilar Artery', 'Brain Infarction', 'Cerebellar Diseases', 'Constriction, Pathologic', 'Diabetes Complications', 'Female', 'Humans', 'Hypertension', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Plaque, Atherosclerotic', 'Pons', 'Smoking', '... | 26,902,678 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.015.114.106'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['C10.228.140.252'], ['C23.300.287'], ['C19.246.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Husfeldt hernia repair: indications and results. A follow-up study. | Ninety-seven consecutive patients with hiatal hernia were operated upon with a modified Husfeldt hernia repair during a ten-year period. Thirty-two of the patients had severe reflux complications, such as ulcerative oesophagitis, oesophageal stricture and shortened oesophagus. Ninety patients were carefully followed up... | ['Adolescent', 'Adult', 'Aged', 'Esophagoplasty', 'Female', 'Follow-Up Studies', 'Gastroesophageal Reflux', 'Hernia, Diaphragmatic', 'Hernia, Hiatal', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Recurrence'] | 7,375,886 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.210.355'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C06.405.117.119.500.484'], ['C23.300.707.960.500'], ['C23.300.707.960.500.467'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Using NSAID in volume depleted children can precipitate acute renal failure. | Non-steroidal anti-inflammatory drugs (NSAID) are increasingly popular in hospital medicine and general practice and are readily available over the counter. The vast majority of healthy children who ingest therapeutic doses of NSAID for a limited duration tolerate them without any significant adverse effects. However, ... | ['Acute Kidney Injury', 'Adolescent', 'Anti-Inflammatory Agents, Non-Steroidal', 'Child', 'Dehydration', 'Female', 'Humans', 'Male'] | 17,293,366 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.057'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['M01.060.406'], ['C18.452.950.179', 'C23.550.274'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enzymatic studies of riboflavin oversynthesis in Eremothecium ashbyii. | Mechanisms of riboflavin oversynthesis in a high flavinogenic mold, Eremothecium ashbyii, were examined in relation to growth, riboflavin formation and related synthases, and medium pH with increasing culture periods. Growth reached maximum at 1 d and then decreased, riboflavin formation proceeded rapidly up to 5 d and... | ['Electrophoresis, Disc', 'Fermentation', 'Hydrogen-Ion Concentration', 'Riboflavin', 'Riboflavin Synthase', 'Saccharomycetales'] | 15,386,926 | [['E05.196.401.402.236', 'E05.301.300.319.403'], ['G02.111.158.249', 'G03.191.249'], ['G02.300'], ['D03.633.100.733.315.650', 'D03.633.300.507.650', 'D08.211.474.650', 'D23.767.405.650'], ['D08.811.913.225.750'], ['B01.300.107.795']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reproducibility and differentiation of cervical arteriopathies using in vivo high-resolution black-blood MRI at 3 T. | INTRODUCTION: The aims of the present study are to evaluate the potential of high-resolution black-blood MRI (hr-bb-cMRI) to differentiate common cervical arteriopathies and to evaluate interobserver reproducibility.METHODS: Forty-three consecutive patients with distinct cervical arteriopathies were examined with cervi... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Carotid Arteries', 'Carotid Artery Diseases', 'Cerebral Angiography', 'Contrast Media', 'Diagnosis, Differential', 'Feasibility Studies', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Angiography', 'Male', 'M... | 26,906,110 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['A07.015.114.186'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['D27.505.2... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A comparative study of neonatal skeletal development in Cebus and other primates. | Comparisons of hand/wrist radiographs of neonatal Cebus albifrons (n = 14) and Cebus apella (n = 4) with those of Saimiri sciureus boliviensis (n = 9) and Macaca mulatta (n = 63) reveal that the cebid monkeys show much less skeletal ossification at birth than macaques. Differences in gestation time alone cannot account... | ['Animals', 'Animals, Newborn', 'Bone Development', 'Carpal Bones', 'Carpus, Animal', 'Cebidae', 'Cebus', 'Female', 'Hand', 'Macaca mulatta', 'Male', 'Osteogenesis', 'Saimiri'] | 2,391,051 | [['B01.050'], ['B01.050.050.282'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['A02.835.232.087.319.150'], ['A13.395.248'], ['B01.050.150.900.649.313.988.400.600.150'], ['B01.050.150.900.649.313.988.400.600.150.170.120'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Double-blind and randomised parallel study of minocycline 100mg (Mynocine) vs roxithromycin 300mg (Rulid), in the treatment of seasonal acute bronchitis in clinical practice]. | 46 general practitioners of the vicinity of Nancy carried out a randomised, parallel and double blind study comparing the efficacity and the tolerance of two drugs: roxithromycin (Rulid) 300 mg per day, and minocycline (Mynocine) 100 mg per day in the treatment of adult acute bronchitis, in clinical practice. 124 patie... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Bronchitis', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Middle Aged', 'Minocycline', 'Roxithromycin', 'Seasonal Affective Disorder'] | 7,754,475 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'],... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Ultrastructure of genital system ducts of Diphyllobothrium latum (Cestoda:Pseudophyllidae): the ducts of the female reproductive system]. | The components of the female reproductive system of Diphyllobothrium latum, including ovary, ovicapt, oviduct, vitelline ducts, vitelline reservoir, vagina, seminal receptacle, ootype with unicellular Mehlis's gland, ootype-uterine duct and uterus were observed with the electron microscope. The epithelium of the female... | ['Animals', 'Diphyllobothrium', 'Esocidae', 'Female', 'Genitalia, Female', 'Microscopy, Electron', 'Ovary', 'Oviducts', 'Uterus', 'Vagina', 'Vitelline Duct'] | 11,962,204 | [['B01.050'], ['B01.050.500.500.736.215.228'], ['B01.050.150.900.493.385.300'], ['A05.360.319'], ['E01.370.350.515.402', 'E05.595.402'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['A13.706'], ['A05.360.319.679'], ['A05.360.319.779'], ['A16.920']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The structure of spongious trabeculae in relation to age in man. | In various bones from 40-50 year old men, numerous osteons were found in spongy trabeculae. As the bones examined are subjected to different mechanical loads, and, in all samples, the osteon frequency appeared to increase with the increase in the trabecular thickness, the endotrabecular osteons was supposed to improve ... | ['Adult', 'Age Factors', 'Aged', 'Femur', 'Humans', 'Male', 'Middle Aged', 'Stress, Mechanical'] | 8,519,493 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G01.374.835']] | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The selective use of magnetic resonance cholangiopancreatography in the imaging of the axial biliary tree in patients with acute gallstone pancreatitis. | BACKGROUND: Magnetic resonance cholangiopancreatography (MRCP) is an emerging modality in the management of acute gallstone pancreatitis (AGP). The aim of this study was to assess the impact following the introduction of MRCP in the management of AGP in a tertiary referral unit.METHODS: Patients presenting with AGP fro... | ['Acute Disease', 'Adult', 'Aged', 'Aged, 80 and over', 'Biliary Tract', 'Cholangiopancreatography, Magnetic Resonance', 'Cholecystectomy', 'Female', 'Gallstones', 'Humans', 'Male', 'Middle Aged', 'Pancreatitis'] | 18,253,063 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.159'], ['E01.370.350.825.500.100', 'E01.370.372.207'], ['E04.210.120.172'], ['C06.130.409.633', 'C06.130.564.332.500', 'C23.300.175.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.689.750']] | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessment of subclinical symptoms and psychological well-being in depression. | A substantial body of research suggests that subclinical symptoms characterize the longitudinal course of major depression and have important pathophysiological and treatment implications. Specific treatment of residual symptoms may in fact improve longterm outcome, by acting on those residual symptoms that progress to... | ['Adaptation, Psychological', 'Depressive Disorder', 'Humans', 'Interpersonal Relations', 'Remission Induction', 'Severity of Illness Index', 'Social Adjustment'] | 11,824,836 | [['F01.058'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E02.860'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['F01.145.813.621']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A comprehensive study of the association between the EGFR and ERBB2 genes and glioma risk. | Glioma is the most common type of adult brain tumor and glioblastoma, its most aggressive form, has a dismal prognosis. Receptor tyrosine kinases such as the epidermal growth factor receptor (EGFR, ERBB2, ERBB3, ERBB4) family, and the vascular endothelial growth factor receptor (VEGFR), play a central role in tumor pro... | ['Adult', 'Aged', 'Brain Neoplasms', 'Case-Control Studies', 'Denmark', 'England', 'ErbB Receptors', 'Female', 'Finland', 'Genotype', 'Glioma', 'Haplotypes', 'Humans', 'Linkage Disequilibrium', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Receptor, ErbB-2', 'Risk Assessment', 'Risk Factors', 'Sweden'] | 20,446,891 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['Z01.542.816.124'], ['Z01.542.363.300'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074']... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prevalence of Salmonella isolates and antimicrobial resistance patterns in chicken meat throughout Japan. | We investigated the prevalence of Salmonella in chicken meat from northern, central, and southern Japan. Between 2006 and 2008, 821 samples from these three regions were collected and examined. Salmonella isolates were detected in 164 (20.0%) of these samples, with 15 (10.0%) of 150, 113 (27.5%) of 411, and 36 (13.8%) ... | ['Animals', 'Anti-Bacterial Agents', 'Chickens', 'Colony Count, Microbial', 'Drug Resistance, Bacterial', 'Food Contamination', 'Food Microbiology', 'Humans', 'Japan', 'Meat', 'Microbial Sensitivity Tests', 'Prevalence', 'Salmonella', 'Salmonella Food Poisoning'] | 21,333,147 | [['B01.050'], ['D27.505.954.122.085'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['H01.158.273.540.274.332', 'J01.576.42... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Predicting successful brachial plexus block using changes in skin electrical resistance. | Skin electrical resistance is determined by the degree of sweating of the skin which is, in turn, related to sympathetic nervous system activity in the area concerned. It is increased when the nerves supplying the area are damaged or blocked by local anaesthetic agents. We have assessed the temporal and spatial relatio... | ['Aged', 'Brachial Plexus', 'Female', 'Galvanic Skin Response', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Nerve Block'] | 3,377,954 | [['M01.060.116.100'], ['A08.800.800.720.050'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E03.155.086.711', 'E04.525.210.550']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultrasonography and nephrotomography in the presymptomatic diagnosis of dominantly inherited (adult-onset) polycystic kidney disease. | Results of an ongoing four-year study evaluating the role of ultrasonography, nephrotomography, and routine excretory urography in the presymptomatic diagnosis of adult polycystic kidney disease (APKD) are reported. Of 39 asymptomatic individuals who were at risk for APKD, 16 had abnormal studies-eight had bilateral re... | ['Adolescent', 'Adult', 'Age Factors', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Kidney', 'Male', 'Polycystic Kidney Diseases', 'Tomography, X-Ray', 'Ultrasonography'] | 7,367,638 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A05.810.453'], ['C12.777.419.403.875', 'C13.351.968.419.403.875', 'C16.131.077.717', 'C16.320.184.625'], ['E01.370.350.700.810', 'E01.370.3... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acceptance of Intanza® 9 ìg intradermal influenza vaccine in routine clinical practice in Australia and Argentina. | INTRODUCTION: Intanza® 9 ìg (Sanofi Pasteur SA, Lyon, France), a split virion trivalent influenza vaccine delivered by intradermal injection with a microinjection system, became available as a vaccination for adults aged 18 to 59 years old, as of the 2010 southern hemisphere influenza season.METHODS: This study was des... | ['Adolescent', 'Adult', 'Argentina', 'Australia', 'Humans', 'Influenza Vaccines', 'Influenza, Human', 'Injections, Intradermal', 'Middle Aged', 'Vaccination', 'Vaccines, Inactivated', 'Young Adult'] | 21,751,080 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.757.077'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['E02.319.267.530.620.410'], ['M01.060.116.630'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Importance of CT-scanning in the evaluation of calcaneal fractures]. | UNLABELLED: The aim of the study is to evaluate the use fullness of CT in the calcaneal fractures.METHODS: We reviewed retrospectively 20 cases of calcaneal fractures collected between 2000 and 2003.RESULTS: We describe the different CT-scan patterns in 20 calcaneal fractures, according to Sanders classification. CT-sc... | ['Accidental Falls', 'Accidents, Home', 'Accidents, Occupational', 'Accidents, Traffic', 'Adolescent', 'Adult', 'Calcaneus', 'Child', 'Female', 'Follow-Up Studies', 'Fractures, Bone', 'Humans', 'Male', 'Prognosis', 'Retrospective Studies', 'Time Factors', 'Tomography, X-Ray Computed'] | 17,424,705 | [['N06.850.135.122'], ['N06.850.135.217'], ['N06.850.135.240'], ['N06.850.135.392'], ['M01.060.057'], ['M01.060.116'], ['A02.835.232.043.300.710.300'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Classification of adhesive domains in the Plasmodium falciparum erythrocyte membrane protein 1 family. | The Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) family of cytoadherent proteins has a central role in disease from malaria infection. This highly diverse gene family is involved in binding interactions between infected erythrocytes and host cells and is expressed in a clonally variant pattern at the e... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Animals', 'Antigenic Variation', 'Antigens, Protozoan', 'Cell Adhesion', 'Cysteine', 'Duffy Blood-Group System', 'Molecular Sequence Data', 'Plasmodium falciparum', 'Protein Structure, Tertiary', 'Protozoan Proteins', 'Sequence Alignment', 'Structure-Activity Relationship'] | 11,071,284 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G05.365.073', 'G12.500.249'], ['D23.050.293'], ['G04.022'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D23.050.301.290.301', 'D23.050.705.230.301'], ['L01.453.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Considering theory in assessing quality of web-based courses. | There are significant implications to jumping on the Internet-course bandwagon, and several questions should be answered before offering or enrolling in such a course. This article provides information on how quality has been assessed with online education, reviews the theoretical framework used in conducting such rese... | ['Education, Distance', 'Education, Nursing', 'Educational Technology', 'Humans', 'Internet', 'Models, Educational', 'Program Evaluation'] | 11,840,067 | [['I02.195'], ['I02.358.462'], ['J01.897.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['E05.599.545', 'I02.903.302'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Combination of PDT and inhibitor treatment affects melanoma cells and spares keratinocytes. | Photodynamic therapy (PDT) is a potential tool in cancer treatment. Today this therapy is established among others for the treatment of nonmelanoma skin cancer. However, the more dangerous skin cancer--the melanoma--still has to be removed by surgery. Therefore, we investigated the effects of PDT and additional adminis... | ['Apoptosis', 'Cells, Cultured', 'Coculture Techniques', 'Combined Modality Therapy', 'Enzyme Inhibitors', 'Heme Oxygenase-1', 'Humans', 'Keratinocytes', 'Light', 'Melanoma', 'Photochemotherapy', 'Poly(ADP-ribose) Polymerase Inhibitors', 'Poly(ADP-ribose) Polymerases', 'Reactive Oxygen Species'] | 21,078,385 | [['G04.146.954.035'], ['A11.251'], ['E05.481.500.374'], ['E02.186'], ['D27.505.519.389'], ['D08.811.682.690.708.410.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.500', 'A11.436.397'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['C04.557.465.625.650.510', 'C04.557.5... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors. | A new series of novel benzo[c]acridine-diones possessing pharmacophoric elements of antitubulins with central dihydropyridine bridge were designed and synthesized as potential anticancer agents and tubulin polymerization inhibitors. The cytotoxic activity of the synthesized compounds was evaluated against eight cancer ... | ['Acridines', 'Antineoplastic Agents', 'Apoptosis', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Drug Design', 'Drug Screening Assays, Antitumor', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Molecular Docking Simulation', 'Molecular S... | 31,012,156 | [['D03.633.300.046'], ['D27.505.954.248'], ['G04.146.954.035'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E01.370.225.500.388', 'E05.200.500.38... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Morphogene adsorption as a Turing instability regulator: Theoretical analysis and possible applications in multicellular embryonic systems. | The Turing instability in the reaction-diffusion system is a widely recognized mechanism of the morphogen gradient self-organization during the embryonic development. One of the essential conditions for such self-organization is sharp difference in the diffusion rates of the reacting substances (morphogens). In classic... | ['Adsorption', 'Algorithms', 'Animals', 'Computer Simulation', 'Diffusion', 'Embryo, Nonmammalian', 'Embryonic Development', 'Models, Biological', 'Models, Theoretical'] | 28,170,437 | [['G01.030', 'G02.020'], ['G17.035', 'L01.224.050'], ['B01.050'], ['L01.224.160'], ['G01.202', 'G02.196'], ['A13.350', 'A16.331'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E05.599.395'], ['E05.599']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The Effects of Sequential Environmental and Harvest Stressors on the Sensory Characteristics of Cultured Channel Catfish (Ictalurus Punctatus) Fillets. | Stress during fish culture alters physiological homeostasis and affects fillet quality. Maintenance of high-quality seafood is important to ensure the production of a marketable product. This study assessed how sequential stressors affect the sensory and quality characteristics of catfish (Ictalurus punctatus) fillets.... | ['Animals', 'Aquaculture', 'Catfishes', 'Consumer Behavior', 'Cooking', 'Environment', 'Humans', 'Hydrogen-Ion Concentration', 'Ictaluridae', 'Seafood', 'Stress, Mechanical', 'Stress, Physiological', 'Taste'] | 27,333,086 | [['B01.050'], ['J01.040.168'], ['B01.050.150.900.493.080'], ['F01.145.236'], ['J01.576.423.200.200'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['B01.050.150.900.493.080.148'], ['G07.203.300.600.875', 'J02.500.600.875'], ['G01.374.835'], ['G07.775'], ['F02.830.816.724', '... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Rules of connectivity between geniculate cells and simple cells in cat primary visual cortex. | Hundreds of thalamic axons ramify within a column of cat visual cortex; yet each layer 4 neuron receives input from only a fraction of them. We have examined the specificity of these connections by recording simultaneously from layer 4 simple cells and cells in the lateral geniculate nucleus with spatially overlapping ... | ['Action Potentials', 'Animals', 'Cats', 'Geniculate Bodies', 'Neurons', 'Photic Stimulation', 'Reaction Time', 'Signal Processing, Computer-Assisted', 'Synapses', 'Synaptic Transmission', 'Visual Cortex'] | 11,356,887 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.317.826.701.444'], ['A08.675', 'A11.671'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['L01.224.800'], ['A08.850', 'A11.284.149.165.420.780'], ['G02... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Misguided presumptions: British Medical Association (BMA) and National Institute for Health and Clinical Excellence (NICE) guidance on organ retrieval and 'opt out' or 'presumed consent'. | Three documents have been produced in an attempt to increase the number of organs available for transplant: a National Institute for Health and Clinical Excellence (NICE) clinical guideline, a British Medical Association (BMA) report and a Welsh Government white paper. All three are ethically flawed: NICE and the BMA r... | ['Health Policy', 'Humans', 'Practice Guidelines as Topic', 'Presumed Consent', 'Societies, Medical', 'State Medicine', 'Tissue and Organ Harvesting', 'United Kingdom'] | 23,342,402 | [['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['I01.880.604.583.659', 'N03.706.535.664'], ['N03.540.828.589'], ['N03.349.550.902', 'N03.858'], ['E04.936.537'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Serial position effects in semantic memory: reconstructing the order of verses of hymns. | Serial position effects (primacy and recency) have been consistently demonstrated in both short- and long-term episodic memory tasks. The search for corresponding effects in semantic memory tasks (e.g., reconstructing the order of U.S. presidents) has been confounded by factors such as differential exposure to stimuli.... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Music', 'Practice, Psychological', 'Religion and Psychology', 'Retention, Psychology', 'Semantics', 'Serial Learning'] | 12,613,688 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['M01.060.116.630'], ['K01.602'], ['F02.463.425.674'], ['F02.880', 'K01.844.664'], ['F02.463.425.540.772'], ['L01.559.598.745'], ['F02.463.425.952.747']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Clinical value and impact on prognosis of peri-operative CA 19-9 serum levels in stage I and II adenocarcinoma of the pancreas. | CA 19-9 is a marker correlated to the clinical evolution of pancreatic adenocarcinoma. To analyze the clinical value of pre- and postoperative CA 19-9 serum levels in stage I and II pancreatic cancer. We analyzed 61 patients resected for pancreatic cancer. Patients were evaluated about the pre-operative CA 19-9 values ... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'CA-19-9 Antigen', 'Carcinoma, Pancreatic Ductal', 'Disease-Free Survival', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Prognosis', 'Retrospective Studies'] | 26,334,620 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['D23.050.285.050.119', 'D23.050.301.290.544.119', 'D23.050.550.325.119', 'D23.050.705.230.544.119', 'D23.101.140.075.119'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.62... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Selective N-heterylazimine inhibition of reactions catalyzed by rat liver glutathione transferase]. | Three reactions (nucleophile substitution, thiolysis and N-deoxygenation) catalyzed by rat liver glutathione transferase have been studied using several N-heterylazimine inhibitors. The inhibitors are sharply different in their effectiveness in the transferase reactions. Their efficiency depends on their structure. The... | ['Animals', 'Catalysis', 'Glutathione Transferase', 'Liver', 'Molecular Structure', 'Oxygen', 'Rats', 'Rats, Wistar', 'Sulfhydryl Compounds'] | 1,413,125 | [['B01.050'], ['G02.130'], ['D08.811.913.225.500'], ['A03.620'], ['G02.111.570', 'G02.466'], ['D01.268.185.550', 'D01.362.670'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D02.886.489']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liquid Chromatographic Chiral Separation of Acenocoumarol and Its Hemiketal Form. | Acenocoumarol, an anticoagulant drug, was separated successfully using polysaccharide-based chiral stationary phases columns namely Cellulose Chiralpak® IB and Chiralcel® OD, using various normal mobile phases by high-performance liquid chromatography. However, the appearance of four well separated peaks confirmed the ... | ['Acenocoumarol', 'Anticoagulants', 'Cellulose', 'Chromatography, High Pressure Liquid', 'Stereoisomerism'] | 28,985,280 | [['D03.383.663.283.446.520.079', 'D03.633.100.150.446.520.079'], ['D27.505.954.502.119'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['E05.196.181.400.300'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Multiplex PCR-based assay for detection of Bordetella pertussis in nasopharyngeal swab specimens. | A multiplex PCR-based assay was developed for the detection of Bordetella pertussis in nasopharyngeal swab specimens. The assay simultaneously amplified two separate DNA targets (153 and 203 bp) within a B. pertussis repetitive element and a 438-bp target within the beta-actin gene of human DNA (PCR amplification contr... | ['Actins', 'Bacteriological Techniques', 'Base Sequence', 'Bordetella pertussis', 'DNA Primers', 'Erythromycin', 'Evaluation Studies as Topic', 'Humans', 'Nasopharynx', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Whooping Cough'] | 8,897,157 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['E01.370.225.875.150', 'E05.200.875.150'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.400.425.115.425.600', 'B03.660.075.090.344.425.600'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D02.540.576.500.992... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The centromeric/nucleolar chromatin protein ZFP-37 may function to specify neuronal nuclear domains. | Murine ZFP-37 is a member of the large family of C2H2 type zinc finger proteins. It is characterized by a truncated NH2-terminal Kr?ppel-associated box and is thought to play a role in transcriptional regulation. During development Zfp-37 mRNA is most abundant in the developing central nervous system, and in the adult ... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Brain', 'COS Cells', 'Cell Nucleolus', 'Cell Nucleus', 'Centromere', 'Chromatin', 'DNA', 'DNA-Binding Proteins', 'Heterochromatin', 'Histones', 'Humans', 'Kruppel-Like Transcription Factors', 'Male', 'Mice', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Neuron... | 9,535,899 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['A08.186.211'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.284.430.106.279.345.175'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['A11.284.430.106.279.345.190.160.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vitro inhibition of pancreatic B cell function by lymphocytes from diabetics with associated autoimmune diseases: a T cell phenomenon. | Lymphocytes from insulin-dependent diabetic patients were previously shown to suppress insulin release from mouse islet cells in vitro. Glucagon release was not suppressed. In order to further analyze this phenomenon, lymphocytes from three insulin-dependent diabetic patients with associated autoimmune diseases were tr... | ['Autoimmune Diseases', 'Diabetes Complications', 'Diabetes Mellitus', 'Humans', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'T-Lymphocytes'] | 6,754,812 | [['C20.111'], ['C19.246.099'], ['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', 'A06.300.414'], ['A11.118.637.555.567.569', 'A15.145.229.637.555.567.569', 'A15.382.490.555.567.569']] | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation. | Lung cancer is frequently complicated by pulmonary infections which may impair prognosis of this disease. Therefore, we investigated the effect of bacterial lipopolysaccharides (LPS) on tumor proliferation in vitro in the non-small cell lung cancer (NSCLC) cell line A549, ex vivo in a tissue culture model using human N... | ['Animals', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Cell Proliferation', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Cyclooxygenase Inhibitors', 'Dinoprostone', 'Disease Models, Animal', 'ErbB Receptors', 'Humans', 'Indomethacin', 'Ki-67 Antigen', 'Lipopolysaccharide Receptors', 'Lipopolysaccharides', 'Lung... | 22,923,191 | [['B01.050'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500',... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunodiagnosis of pulmonary hydatid disease in a patient with negative radiologic and scintillographic findings. | Hydatid disease was diagnosed by the arc 5 double diffusion (DD5) test in a patient with concomitant pulmonary disease. The localization of the cysts could not be determined by radiologic and scintillographic studies of the lung and abdomen. The hydatid nature of fluid collected by pleural puncture required for the con... | ['Adult', 'Echinococcosis, Pulmonary', 'Humans', 'Immunodiffusion', 'Male'] | 3,923,665 | [['M01.060.116'], ['C01.610.335.190.396.480', 'C01.610.582.314', 'C01.748.450.314', 'C08.381.517.314', 'C08.730.450.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
3-Alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides structurally related to diazoxide and pinacidil as potassium channel openers acting on vascular smooth muscle cells: design, synthesis, and pharmacological evaluation. | A series of 3-alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1, 1-dioxides structurally related to diazoxide and pinacidil were synthesized and tested as possible K(ATP) channel openers on isolated pancreatic endocrine tissue as well as on isolated vascular, intestinal, and uterine smooth muscle. In contrast to previous... | ['Animals', 'Aorta', 'Cyclic S-Oxides', 'Diazoxide', 'Drug Design', 'Female', 'Guinea Pigs', 'Ileum', 'In Vitro Techniques', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Pinacidil', 'Potassium Channels', 'Rats', 'Rats, Wistar', 'Structure-Activity Relationsh... | 10,780,901 | [['B01.050'], ['A07.015.114.056'], ['D02.886.124', 'D03.661.493'], ['D02.886.590.700.135.300', 'D02.886.655.500.300', 'D03.633.100.174.300'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B01.050.150.900.649.313.992.550'], ['A03.556.124.684.249', 'A03.556.249.124'], ['E05.481'], ['D06.472.699.587... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Definition of adult-onset rheumatoid arthritis from elderly-onset rheumatoid arthritis by studying T-lymphocyte subpopulations, their soluble receptors and soluble receptor of interleukin-2. | AIMS: The study of the distribution of T-lymphocyte sub-populations has revealed some immune characteristics of rheumatoid arthritis (RA) as well as polymyalgia rheumatica (PMR). There is much evidence that the subsets of T-lymphocyte subpopulations are well correlated with the age of the patient and the precise diagno... | ['Adult', 'Age of Onset', 'Aged', 'Arthritis, Rheumatoid', 'CD4-Positive T-Lymphocytes', 'CD57 Antigens', 'CD8-Positive T-Lymphocytes', 'Diagnosis, Differential', 'Female', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Polymyalgia Rheumatica', 'Receptors, Interleukin-2', 'T-Lymphocyte Subsets'] | 17,953,280 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D23.050.301.264.894.157', 'D23.101.100.894.157'], ['A11.118.63... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ovarian hormone replacement affects cocaine-induced behaviors in ovariectomized female rats. | To determine whether cocaine-induced behavioral alterations are modulated by ovarian hormones, ovariectomized rats were randomly assigned to one of two drug treatment conditions: "binge" cocaine (three 15-mg/kg intraperitoneal (ip) injections, 1 h apart) or saline administration; and four hormone pretreatment sub-group... | ['Animals', 'Cocaine', 'Dopamine Uptake Inhibitors', 'Drug Therapy, Combination', 'Estrogens', 'Female', 'Hormone Replacement Therapy', 'Motor Activity', 'Ovariectomy', 'Progesterone', 'Rats', 'Rats, Inbred F344'] | 11,164,068 | [['B01.050'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D27.505.519.562.437.220', 'D27.505.519.625.150.800', 'D27.505.519.625.600.220', 'D27.505.696.577.150.800', 'D27.505.696.577.600.220'], ['E02.319.310'], ['D27.505.696.399.472.277'], ['E02.319.452'], ['F01.145.632', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetic model of R-roscovitine and its metabolite in healthy male subjects. | OBJECTIVE: To characterize the pharmacokinetics of R-roscovitine, a novel cyclin-dependent kinase inhibitor, and its carboxylate metabolite in man.METHOD: Twelve healthy male subjects received single oral doses of 50, 100, 200, 400 or 800 mg in a hierarchical 3-period, 6-sequence crossover design. One dose was given af... | ['Adult', 'Area Under Curve', 'CDC2-CDC28 Kinases', 'Cross-Over Studies', 'Cyclin E', 'Cyclin-Dependent Kinase 2', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Food-Drug Interactions', 'Half-Life', 'Humans', 'Male', 'Metabolic Clearance Rate', 'Middle Aged', 'Models, Biological', 'Purines', 'Roscovitine', ... | 15,124,981 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D08.811.913.696.620.682.700.646.500.500', 'D12.644.360.250.067', 'D12.776.167.200.067', 'D12.776.476.250.067'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D12.644.360.262.180', 'D12.776.167.218.18... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of pretreatment with epoxy compounds on the mechanical properties of bovine pericardial bioprosthetic materials. | Early failures of bovine pericardial heart valves are due to leaflet perforation, tearing and calcification. Since glutaraldehyde fixation has been shown to produce marked changes in leaflet mechanics and has been linked to development of calcification, bovine pericardium fixed with the four hydrophilic epoxy formulati... | ['Animals', 'Bioprosthesis', 'Cattle', 'Epoxy Compounds', 'Glutaral', 'Heart Valve Prosthesis', 'Pericardium', 'Prosthesis Design', 'Stress, Mechanical', 'Tensile Strength'] | 1,432,579 | [['B01.050'], ['E07.695.100'], ['B01.050.150.900.649.313.500.380.271'], ['D02.355.291.411'], ['D02.047.532'], ['E07.695.310'], ['A07.541.795', 'A10.615.789.470'], ['E05.320.550', 'E07.695.680'], ['G01.374.835'], ['G01.374.850']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Streptococcus mutans SMU.623c codes for a functional, metal-dependent polysaccharide deacetylase that modulates interactions with salivary agglutinin. | The genome sequence of the oral pathogen Streptococcus mutans predicts the presence of two putative polysaccharide deacetylases. The first, designated PgdA in this paper, shows homology to the catalytic domains of peptidoglycan deacetylases from Streptococcus pneumoniae and Listeria monocytogenes, which are both though... | ['Agglutinins', 'Amidohydrolases', 'Bacterial Proteins', 'Carbohydrate Sequence', 'Cell Adhesion', 'Chitin', 'Chromosomes, Bacterial', 'DNA, Bacterial', 'Gene Knockout Techniques', 'Genetic Predisposition to Disease', 'Metals', 'Muramidase', 'Oligosaccharides', 'Peptidoglycan', 'Polymerase Chain Reaction', 'Saliva', 'S... | 18,978,064 | [['D27.505.696.477.136', 'D27.505.954.502.270.232'], ['D08.811.277.087'], ['D12.776.097'], ['G02.111.570.160', 'L01.453.245.667.160'], ['G04.022'], ['D05.750.078.139', 'D09.698.211'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['D13.444.308.212'], ['E05.393.335.750'], ['C23.550.291.687.500', 'G05.380.355'], ['D... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The importance of slice location on the accuracy of aortic regurgitation measurements with magnetic resonance phase velocity mapping. | Although several methods have been used clinically to evaluate the severity of aortic regurgitation, there is no purely quantitative approach for aortic regurgitant volume (ARV) measurements. Magnetic resonance phase velocity mapping can be used to quantify the ARV, with a single imaging slice in the ascending aorta, f... | ['Animals', 'Aorta', 'Aortic Valve', 'Aortic Valve Insufficiency', 'Blood Flow Velocity', 'Compliance', 'Coronary Circulation', 'In Vitro Techniques', 'Magnetic Resonance Imaging', 'Models, Cardiovascular', 'Observer Variation', 'Pulsatile Flow', 'Swine'] | 9,236,977 | [['B01.050'], ['A07.015.114.056'], ['A07.541.510.110'], ['C14.280.484.048.500'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G01.374.590.210'], ['G09.330.100.324'], ['E05.481'], ['E01.370.350.825.500'], ['E05.599.395.161'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['G01.482.62... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Constructing and analyzing the fitness landscape of an experimental evolutionary process. | Iterative saturation mutagenesis (ISM) is a promising approach to more efficient directed evolution, especially for enhancing the enantioselectivity and/or thermostability of enzymes. This was demonstrated previously for an epoxide hydrolase (EH), after five sets of mutations led to a stepwise increase in enantioselect... | ['Catalytic Domain', 'Directed Molecular Evolution', 'Epistasis, Genetic', 'Mutagenesis', 'Mutation', 'Thermodynamics'] | 18,712,749 | [['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.393.420.175'], ['G05.308.207'], ['G05.558'], ['G05.365.590'], ['G01.906']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular cloning and characterization of alpha1-soluble guanylyl cyclase gene promoter in rat pituitary cells. | Soluble guanylyl cyclase is a cytosolic enzyme which catalyzes conversion of GTP to the second messenger cyclic GMP. The transcriptional regulation at the promoter levels of four soluble guanylyl cyclase subunits, termed alpha1, alpha2, beta1, and beta2, is largely unknown. In this study, we identified the transcriptio... | ["5' Flanking Region", 'Animals', 'Base Sequence', 'Binding Sites', 'CCAAT-Binding Factor', 'Cells, Cultured', 'Cloning, Molecular', 'Female', 'Gene Deletion', 'Guanylate Cyclase', 'Molecular Sequence Data', 'Mutation', 'Pituitary Gland', 'Promoter Regions, Genetic', 'Protein Binding', 'Rats', 'Rats, Sprague-Dawley', '... | 17,170,090 | [['G05.360.340.024.220.282', 'G05.360.340.024.340.137.295'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D12.776.260.108.124.249', 'D12.776.660.167.249', 'D12.776.930.127.124.249'], ['A11.251'], ['E05.393.220'], ['G05.365.590.762.320', 'G05.558.800.320'], ['D08.811.520... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Management of gastric lymphoma. | INTRODUCTION: The management of gastric lymphoma is controversial and a wide variety of unimodality or multimodality approaches have been used. The aim of this report is to highlight the variety of treatment regimens deployed, the outcomes achieved and to present a modern management approach for this enigmatic tumour.R... | ['Adult', 'Aged', 'Aged, 80 and over', 'Combined Modality Therapy', 'Female', 'Humans', 'Lymphoma', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Palliative Care', 'Stomach Neoplasms', 'Survival Rate', 'Treatment Outcome'] | 18,939,371 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['M01.060.116.630'], ['E01.789.625'], ['E02.760.666', 'N02.421.585.666'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Total and Trimester-Specific Gestational Weight Gain and Offspring Birth and Early Childhood Weight: A Prospective Cohort Study on Monozygotic Twin Mothers and Their Offspring. | Gestational weight gain (GWG) has in numerous studies been associated with offspring birth weight (BW) and childhood weight. However, these associations might be explained by genetic confounding as offspring inherit their mother's genetic potential to gain weight. Furthermore, little is known about whether particular p... | ['Adult', 'Birth Weight', 'Body Mass Index', 'Child', 'Child, Preschool', 'Female', 'Gestational Age', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Pregnancy', 'Pregnancy Trimesters', 'Pregnancy, Twin', 'Sweden', 'Twins, Monozygotic', 'Weight Gain'] | 27,161,254 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['M01.060.406.448'], ['G07.345.500.325.235.968', 'G08.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Glucose-sensitive gel rheology of dextran-concanavalin A mixtures suitable for self-regulating insulin delivery. | Aqueous concentrated plain mixtures of dextran and concanavalin A (con A) were examined for their rheological response to glucose for comparison with previously studied partially photopolymerized acrylic derivatives. Non-destructive oscillatory tests were undertaken within the linear viscoelastic range to examine the r... | ['Blood Glucose', 'Concanavalin A', 'Dextrans', 'Diabetes Mellitus', 'Drug Delivery Systems', 'Gels', 'Glucose', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Molecular Weight', 'Rheology', 'Technology, Pharmaceutical', 'Temperature', 'Viscosity'] | 19,505,210 | [['D09.947.875.359.448.500'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D05.750.078.562.272', 'D09.698.365.272'], ['C18.452.394.750', 'C19.246'], ['E02.319.300'], ['D20.280.320', 'D26.255.165.320'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Thumb Carpometacarpal Joint Stabilization in Ehlers-Danlos Syndrome--Case Report. | We report the case of an 18-years-old patient with thumb carpometacarpal ligament laxity due to Ehlers-Danlos syndrome who was treated with trapezial opening wedge osteotomy combined with volar ligaments reconstruction. Two years postoperatively she is pain free and the thumb carpometacarpal joint is stable. | ['Adolescent', 'Carpometacarpal Joints', 'Ehlers-Danlos Syndrome', 'Female', 'Humans', 'Osteotomy', 'Radiography', 'Thumb', 'Trapezium Bone'] | 26,388,011 | [['M01.060.057'], ['A02.835.583.405.200'], ['C14.907.454.240', 'C15.378.463.515.240', 'C16.131.831.428', 'C16.320.850.260', 'C17.300.200.310', 'C17.800.804.428', 'C17.800.827.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.555.580'], ['E01.370.350.700'], ['A01.378.800.667.430.705'], ['A02.835.232.087.319.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Complication and failure rates of tooth-supported fixed dental prostheses after 7 to 19 years in function. | PURPOSE: The aims of this study were to reexamine patients who had received fixed dental prostheses (FDPs) more than 10 years prior, list the frequencies of observed technical and biologic failures and complications, and calculate the estimated failure and complication rates at 10 and 15 years.MATERIALS AND METHODS: Fi... | ['Dental Prosthesis', 'Humans', 'Tooth'] | 22,720,287 | [['E06.780.346', 'E07.695.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microbial population response to changes of the operating conditions in a dynamic nutrient-removal sequencing batch reactor. | A nutrient-removal sequencing batch reactor operated with short anaerobic/aerobic cycles was subjected to different operating conditions, namely, cycle length, feeding pattern and feed composition. The changes in microbial population, as well as the contribution of microbial groups to the total nutrient removal, were e... | ['Aerobiosis', 'Anaerobiosis', 'Bioreactors', 'Nitrogen', 'Phosphorus', 'Waste Disposal, Fluid', 'Water Purification'] | 16,215,726 | [['G02.111.017', 'G03.049'], ['G02.111.062', 'G03.078'], ['E07.115', 'J01.897.120.115'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Unaltered immunocompetence in patients with non-disseminated breast cancer at the time of diagnosis. | Immunologic parameters were examined preoperatively in 104 patients with breast cancer, staged according to the TNM classification and in 95 age-matched healthy women. The immunologic evaluation in the peripheral blood included lymphocyte and monocyte counts, determination of E-rosette-forming T-lymphocytes (SER+) and ... | ['Adult', 'Aged', 'B-Lymphocytes', 'Breast Neoplasms', 'Cells, Cultured', 'Colony-Forming Units Assay', 'Female', 'Humans', 'Leukocyte Count', 'Lymphocyte Activation', 'Middle Aged', 'Monocytes', 'Neoplasm Staging', 'T-Lymphocytes'] | 3,872,158 | [['M01.060.116'], ['M01.060.116.100'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C04.588.180', 'C17.800.090.500'], ['A11.251'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Significance of carbohydrate epitopes in a latex allergen with beta-1,3-glucanase activity. | BACKGROUND: One of the latex allergens, Hev b 2, has beta-1,3-glucanase activity. The entire sequence of this allergen is already known. There is one potential N-glycosylation site in this molecule ((27)Asn). Heterogeneous glycosylation of this Asn residue could be a source of the multiplicity of natural Hev b 2. Possi... | ['Adult', 'Allergens', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Female', 'Glucan 1,3-beta-Glucosidase', 'Humans', 'Immunoglobulin E', 'Isoenzymes', 'Latex Hypersensitivity', 'Male', 'Middle Aged', 'beta-Glucosidase'] | 12,372,996 | [['M01.060.116'], ['D23.050.063'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D23.050.550'], ['D08.811.277.450.420.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reversal of oligohydramnios with subtotal immersion: a report of five cases. | OBJECTIVE: The purpose was to summarize five cases where subtotal immersion was associated with an increase in the amniotic fluid index.STUDY DESIGN: Five women with oligohydramnios, as defined by an amniotic fluid index < 8 cm, who underwent subtotal (shoulder-deep) immersion therapy are described.RESULTS: The mean pr... | ['Adult', 'Amniotic Fluid', 'Female', 'Humans', 'Immersion', 'Oligohydramnios', 'Pregnancy'] | 8,267,068 | [['M01.060.116'], ['A12.098', 'A16.378.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.466'], ['C13.703.560'], ['G08.686.784.769']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The comparative histopathology of primary and secondary lesions in murine salmonellosis. | In a primary infection, Swiss-Webster mice were injected i.p. with 10(2) or 10(3) virulent Salmonella typhimurium. Multiple microscopic acute abscesses with predominantly polymorphonuclear leucocytes (PMNs) were seen in the liver and the spleen beginning on the 4th day after infection. By the 7th day, these lesions had... | ['Animals', 'Immunization', 'Liver', 'Mice', 'Necrosis', 'Neutrophils', 'Salmonella Infections', 'Salmonella typhimurium', 'Spleen', 'Time Factors'] | 6,990,953 | [['B01.050'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['C23.550.717'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Isolated Distal Deep Vein Thrombosis: Perspectives from the GARFIELD-VTE Registry. | Isolated distal deep vein thrombosis (IDDVT) represents up to half of all lower limb DVT. This study investigated treatment patterns and outcomes in 2,145 patients with IDDVT in comparison with those with proximal DVT (PDVT; n = 3,846) and pulmonary embolism (PE; n = 4,097) enrolled in the GARFIELD-VTE registry. IDDVT ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anticoagulants', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prospective Studies', 'Pulmonary Embolism', 'Recurrence', 'Registries', 'Risk', 'Treatment Outcome', 'Venous Thromboembolism', 'Venous Thrombosis'] | 31,370,075 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.502.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arsenic in coal of the Thar coalfield, Pakistan, and its behavior during combustion. | The aim of the current study is to evaluate the occurrence of arsenic in coal collected from Thar coalfield, Pakistan, and its behavior during the combustion. Fractionation of arsenic (As) in coal samples was carried out by Community Bureau of Reference sequential extraction scheme (BCR-SES) and single-step-based BCR m... | ['Arsenic', 'Chemical Fractionation', 'Coal', 'Hot Temperature', 'Mining', 'Pakistan', 'Spectrophotometry, Atomic'] | 25,561,265 | [['D01.268.513.249'], ['E05.196.155'], ['D20.345.108', 'N06.230.132.258.108'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['J01.576.655.875.500'], ['Z01.252.245.723'], ['E05.196.712.726.551', 'E05.196.867.826.551']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Cisplatin-induced neuropathic pain is mediated by upregulation of N-type voltage-gated calcium channels in dorsal root ganglion neurons. | Cisplatin is important in the treatment of various types of cancer. Although it is highly effective, it also has severe side effects, with neurotoxicity in dorsal root ganglion (DRG) neurons being one of the most common. The key mechanisms of neurotoxicity are still controversially discussed; however, disturbances of t... | ['Animals', 'Antineoplastic Agents', 'Benzylamines', 'Calcium Channel Blockers', 'Calcium Channels, N-Type', 'Cells, Cultured', 'Cisplatin', 'Disease Models, Animal', 'Female', 'Ganglia, Spinal', 'Male', 'Membrane Potentials', 'Motor Activity', 'Neuralgia', 'Pain Measurement', 'Rats', 'Rats, Sprague-Dawley', 'Rats, Wis... | 27,823,926 | [['B01.050'], ['D27.505.954.248'], ['D02.092.200', 'D02.455.426.559.389.140.210'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150.585', 'D12.776.543.550.450.150.585', 'D12.776.543.585.400.150.585'], ['A11.251'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['C22.232',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On the automatic evaluation of social exemplars. | The present article focuses on the automatic evaluation of exemplars whose category membership has been learned in the past. Studies 1 and 2 confirmed the hypothesis that once an exemplar has been encoded as a member of a given group, at a later encounter the evaluation associated with the group will be unintentionally... | ['Automatism', 'Female', 'Humans', 'Male', 'Random Allocation', 'Reaction Time', 'Signal Detection, Psychological', 'Social Environment'] | 15,008,643 | [['F02.463.425.179.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['E01.370.685.814', 'E05.796.908', 'F02.463.593.257.800', 'F02.463.593.710.725', 'F04.096.753.814... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Accumulation of urinary cancer-related glycoprotein, EDCl, in psoriasis. | EDCl is a novel glycoprotein, mol wt 27,000, isolated in 1976 from leukemic urine. It inhibits the serine proteases trypsin and chymotrypsin and is antigenically related to interalpha trypsin inhibitor (IATI), mol wt 170,000, a normal plasma antiprotease. Since psoriasis is a non neoplastic hyperproliferative state, we... | ['Adult', 'Aged', 'Female', 'Glycoproteins', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Proteins', 'Psoriasis'] | 479,629 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aggressiveness, anger, and hostility in eating disorders. | OBJECTIVE: Despite evidence of a link between the behavioral and cognitive dimensions of aggressiveness and eating disorders, only few studies have tested this relation empirically.METHODS: A total of 112 female patients with anorexia nervosa (n = 61) or bulimia nervosa (n = 51) and 631 young girls attending 7 high sch... | ['Adolescent', 'Aggression', 'Anger', 'Anorexia Nervosa', 'Body Image', 'Bulimia Nervosa', 'Female', 'Hostility', 'Humans', 'Italy', 'Personality Inventory', 'Psychometrics', 'Reproducibility of Results'] | 18,555,057 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.470.093'], ['F03.400.125'], ['F01.752.747.792.110', 'F02.463.593.112'], ['F03.400.250'], ['F01.470.596'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['F04.711.647.513'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.36... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Why extreme dilutions reach non-zero asymptotes: a nanoparticulate hypothesis based on froth flotation. | Extreme dilutions, especially homeopathic remedies of 30c, 200c, and higher potencies, are prepared by a process of serial dilution of 1:100 per step. As a result, dilution factors of 10(60), 10(400), or even greater are achieved. Therefore, both the presence of any active ingredient and the therapeutic efficacy of the... | ['Gold', 'Lactose', 'Mass Spectrometry', 'Metal Nanoparticles', 'Particle Size', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties', 'Zinc'] | 23,083,226 | [['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D09.698.629.305.340', 'D09.947.750.340'], ['E05.196.566'], ['J01.637.512.600.500'], ['G02.712'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['G02.860'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Protein binding studies of furosemide and penbutolol. | Serum protein binding of furosemide and penbutolol, the active principles of Betasemid (Hoe 9358), was studied by equilibrium dialysis. Membranes from commercial dialysis tubes were used within commercially available cells. Serum drug and portion unbound in buffer were determined by quantitative thin-layer chromatograp... | ['Blood Proteins', 'Buffers', 'Chromatography, Thin Layer', 'Dialysis', 'Furosemide', 'Humans', 'In Vitro Techniques', 'Kinetics', 'Penbutolol', 'Propanolamines', 'Protein Binding', 'Ultrafiltration'] | 4,026,914 | [['D12.776.124'], ['D27.720.470.280'], ['E05.196.181.400.537'], ['E05.196.353', 'G02.186'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['D02.033.100.624.698.688', 'D02.033.755.624.698.688', 'D02... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of a digitonin disk assay to discriminate between acholeplasma and mycoplasma isolates from bovine milk. | A study was undertaken to evaluate effectiveness of a digitonin disk inhibition test to discriminate between Acholeplasma laidlawii and Mycoplasma sp. isolated from bovine milk. The test measured zone diameters of growth inhibition surrounding a digitonin-containing disk on solid medium. Zones of inhibition for 20 isol... | ['Acholeplasma laidlawii', 'Animals', 'Digitonin', 'Evaluation Studies as Topic', 'Microbial Sensitivity Tests', 'Milk', 'Mycoplasma'] | 2,912,675 | [['B03.440.860.074.150.500'], ['B01.050'], ['D04.210.500.155.580.130.500.236', 'D09.408.180.261.236'], ['E05.337', 'N05.715.360.335'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['B03.440.860.580.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Defective glucose counterregulation after subcutaneous insulin in noninsulin-dependent diabetes mellitus. Paradoxical suppression of glucose utilization and lack of compensatory increase in glucose production, roles of insulin resistance, abnormal neuroendocrine responses, and islet paracrine interactions. | To characterize glucose counterregulatory mechanisms in patients with noninsulin-dependent diabetes mellitus (NIDDM) and to test the hypothesis that the increase in glucagon secretion during hypoglycemia occurs primarily via a paracrine islet A-B cell interaction, we examined the effects of a subcutaneously injected th... | ['Adult', 'Blood Glucose', 'Blood Pressure', 'C-Peptide', 'Diabetes Mellitus, Type 2', 'Female', 'Glucose', 'Glycated Hemoglobin A', 'Glycolysis', 'Heart Rate', 'Hormones', 'Humans', 'Injections, Subcutaneous', 'Insulin', 'Kinetics', 'Male', 'Middle Aged', 'Reference Values'] | 6,373,827 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.947.875.359.448'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cri du chat syndrome determined by the 5p15.3-->pter deletion--diagnostic problems. | A cytogenetic analysis was performed on an 8-day-old girl, who was suspected of Cri du chat syndrome (CdCS) on the basis of a cat-like cry, despite her dysmorphic features not being characteristic of this syndrome. The cytogenetic analysis revealed a partial deletion of the short arm of chromosome 5, but did not allow ... | ['Abnormalities, Multiple', 'Chromosome Deletion', 'Chromosome Inversion', 'Chromosomes, Human, Pair 5', 'Cri-du-Chat Syndrome', 'Developmental Disabilities', 'Female', 'Genotype', 'Humans', 'In Situ Hybridization', 'Infant, Newborn', 'Phenotype'] | 16,473,315 | [['C16.131.077'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['A11.284.187.520.300.280.290', 'G05.360.162.520.300.280.290'], ... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Engaging vulnerable adolescents in a pregnancy prevention program: perspectives of Prime Time staff. | INTRODUCTION: Evaluating interventions for reducing unintended adolescent pregnancy is necessary to ensure quality and efficacy. The purpose of this study was to examine core case management practices and processes for engaging high-risk girls in Prime Time, an intensive multi-component intervention from the perspectiv... | ['Adolescent', 'Contraception Behavior', 'Family Planning Services', 'Female', 'Humans', 'Motivation', 'Organizational Objectives', 'Outcome and Process Assessment, Health Care', 'Pregnancy', 'Pregnancy in Adolescence', 'Pregnancy, Unwanted', 'School Health Services', 'Sexual Behavior', 'United States'] | 22,726,710 | [['M01.060.057'], ['F01.145.688.500', 'G08.686.784.891.500'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['N04.452.615'], ['N04.761.559', 'N05.715.360.575'], ['G08.686.784.769'], ['G08.686.784.769.494'], ['G08.686.784.769.580'], ['N02.421... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A novel mechanism for oral controlled release of drugs by continuous degradation of a phospholipid prodrug along the intestine: in-vivo and in-vitro evaluation of an indomethacin-lecithin conjugate. | PURPOSE: To investigate a novel mechanism for oral controlled release of drugs involving a continuous degradation of a phospholipid prodrug along the intestine. An indomethacin-lecithin conjugate with the drug attached to the sn-2 position of the phospholipid through a 5-carbon linker (DP-155) was used as a model molec... | ['Administration, Oral', 'Animals', 'Biological Availability', 'Delayed-Action Preparations', 'Drug Evaluation, Preclinical', 'Indomethacin', 'Intestinal Mucosa', 'Intestines', 'Male', 'Phosphatidylcholines', 'Phospholipids', 'Prodrugs', 'Rats', 'Rats, Wistar'] | 17,382,425 | [['E02.319.267.100'], ['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['D26.255.210', 'E02.319.300.253'], ['E05.290.750', 'E05.337.550'], ['D03.633.100.473.420'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['D10.570.755.375.760.400.800'], ['D10.570.755'], ['D26.675'], ['B01.050.150.900.649.313.992.635.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Auditory-visual shift in localization depending on gaze direction. | The effect of eye position on the spatial congruence of the perceived direction of auditory and visual cues was investigated, using a two-alternative forced choice method in combination with a visual fixation task. The azimuth of the sound was perceived as slightly shifted to the left of a visual reference when the gaz... | ['Adult', 'Auditory Perception', 'Eye Movements', 'Female', 'Humans', 'Male', 'Posture', 'Visual Perception'] | 8,905,695 | [['M01.060.116'], ['F02.463.593.071', 'G07.888.125'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.695'], ['F02.463.593.932']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Study on the intra-tumor tissue concentration of zinostatin stimalamer in the liver following intra-arterial injection of zinostatin stimalamer (YM881) suspension]. | A suspension of zinostatin stimalamer (YM881), an antitumor protein antibiotic in iodized poppy oil-fatty acid ester, was injected into the hepatic artery of 2 patients who received surgical treatment of hepatic tumors. Single doses of 4 mg of zinostatin stimalamer were injected into the hepatic artery by Seldinger's m... | ['Aged', 'Carcinoma, Hepatocellular', 'Female', 'Hepatic Artery', 'Humans', 'Injections, Intra-Arterial', 'Liver Neoplasms', 'Male', 'Maleic Anhydrides', 'Middle Aged', 'Polystyrenes', 'Zinostatin'] | 1,651,687 | [['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A07.015.114.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.370'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['D02.113.450', 'D03.383.312.520'], ['M01.060.116.630'], ['D02... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Large granular lymphocyte leukemia with pure red cell aplasia in a renal transplant recipient. | Neoplastic disorders sometimes accompany a renal transplant. Herein, we report a large granular lymphocyte (LGL) leukemia patient with pure red cell aplasia (PRCA) after renal transplantation. A 36-year-old female was presented to our department with anemia in February 1996. She had undergone hemodialysis because of pr... | ['Adult', 'Cyclosporine', 'Female', 'Gene Rearrangement, beta-Chain T-Cell Antigen Receptor', 'Humans', 'Immunophenotyping', 'Immunosuppression', 'Immunosuppressive Agents', 'Kidney Transplantation', 'Leukemia, Lymphoid', 'Red-Cell Aplasia, Pure'] | 9,423,821 | [['M01.060.116'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G05.344.801.211', 'G12.500.287.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['E02.095.465.425.450', 'E05.478.610'], ['D27.505.696.477.656'], ['E02.870.500', 'E04.936.450.485', 'E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment of rheumatoid arthritis with desferrioxamine. | Desferrioxamine was used to treat six patients who had rheumatoid arthritis refractory to conventional treatment, on the basis that levels of intra-articular iron would be reduced and inflammation lessened. After a period of initial intensive treatment which was limited by side effects, five patients continued on once-... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Deferoxamine', 'Drug Evaluation', 'Female', 'Humans', 'Infusions, Parenteral', 'Male', 'Middle Aged'] | 3,659,252 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Technical quality assurance in diagnostic ultrasound in outpatient care in Germany]. | PURPOSE: Technical quality assurance in diagnostic ultrasound is based on nationally standardized protocols which are mandatory for outpatient care in Germany. Quality assurance includes technical requirements for sonographic instruments based on limiting values for technical parameters and requirements for image quali... | ['Ambulatory Care', 'Clinical Competence', 'Equipment Design', 'Germany', 'Humans', 'National Health Programs', 'Quality Assurance, Health Care', 'Ultrasonography'] | 22,872,382 | [['E02.760.106', 'N02.421.585.106'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.320'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550'], ['N04.761.700', 'N05.700'], ['E01.370.350.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
EEG techniques in the measurement of the severity of depressive syndromes. | Previous results from our laboratory support the hypothesis that measurements of EEG mean integrated amplitude (MIA) are correlated with the depth of depression as assessed by a rating scale, and also with the degree of memory impairment during depression. Moreover, it could be shown that there occurs, during severe de... | ['Adult', 'Bipolar Disorder', 'Depression', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Humans', 'Male', 'Middle Aged', 'Photic Stimulation'] | 1,223,665 | [['M01.060.116'], ['F03.084.500'], ['F01.145.126.350'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.723.729']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Radiotherapy in the combined modality treatment of patients with malignant tumors]. | Proceeding from an analysis of their own experience in the combined treatment of over 4000 patients with malignant tumors of the main sites, the authors evaluate the importance of the methodological aspects of pre- and post-operative radiation therapy: levels of total absorbed doses, techniques of their fractionation, ... | ['Combined Modality Therapy', 'Humans', 'Hyperbaric Oxygenation', 'Neoplasms', 'Prognosis'] | 3,343,898 | [['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.880.690.490'], ['C04'], ['E01.789']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differences in cell-to-cell spread of pathogenic and apathogenic rabies virus in vivo and in vitro. | Pathogenic parental rabies virus and apathogenic variant virus were shown to differ in their ability to infect neurons in vivo and neuroblastoma cells in vitro. After intracerebral inoculation, the distribution of infected neurons in the brain was similar for both viruses, but the rate of spread throughout the brain, t... | ['Animals', 'Cells, Cultured', 'Cerebellum', 'Cricetinae', 'Immunoenzyme Techniques', 'Mice', 'Neurons', 'Rabies virus', 'Receptors, Virus', 'Viral Proteins', 'Virus Replication'] | 3,897,571 | [['B01.050'], ['A11.251'], ['A08.186.211.132.810.428.200'], ['B01.050.150.900.649.313.992.635.075.250'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['A08.675', 'A11.671'], ['B04.820.480.937.750.500.700'], ['D12.776.543.750.830'], ['D12.776.964'], ['G06.920.92... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Detailed Characterization of the Dysfunctional Immunity and Abnormal Myelopoiesis Induced by Severe Shock and Trauma in the Aged. | The elderly are particularly susceptible to trauma, and their outcomes are frequently dismal. Such patients often have complicated clinical courses and ultimately die of infection and sepsis. Recent research has revealed that although elderly subjects have increased baseline inflammation as compared with their younger ... | ['Adult', 'Age Factors', 'Aged', 'Aging', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Cells, Cultured', 'Cohort Studies', 'Female', 'Humans', 'Immunity', 'Leukocytes', 'Male', 'Mice, Inbred C57BL', 'Middle Aged', 'Myelopoiesis', 'Oligonucleotide Array Sequence Analysis', 'Pneumonia, Ventilator-Associated', 'Pseudomonas... | 26,246,141 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G07.345.124'], ['B01.050'], ['E05.927.100.500'], ['A11.251'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['A11.118.637', 'A15.145.229.637', '... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Verbal fluency test--developmental aspects in health and illness]. | INTRODUCTION: The Verbal Fluency Test is one of the easiest method in the neuropsychological evaluation of the frontal and temporal lobes' functioning. The amount of reasearch considering children's performance is still small compared to the adult population. The test lacks polish norms (as well as norms for children i... | ['Adolescent', 'Child', 'Developmental Disabilities', 'Epilepsy', 'Female', 'Headache', 'Humans', 'Male', 'Neuropsychological Tests', 'Speech Disorders'] | 19,205,357 | [['M01.060.057'], ['M01.060.406'], ['F03.625.421'], ['C10.228.140.490'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['C10.597.606.150.500.800', 'C23.888.592.604.150.500.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A comparison of oral health in elderly populations seeking and not seeking dental care. | The General Oral Health Assessment Index (GOHAI) has been recommended for use as an outcome measure in the evaluation of dental treatment. This study was designed to assess the ability of the GOHAI in the evaluation of differences in those actively seeking dental care compared with those not seeking care. GOHAI was sel... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Attitude to Health', 'Chi-Square Distribution', 'Confidence Intervals', 'Dental Care for Aged', 'Dental Clinics', 'Dental Prosthesis', 'Female', 'Health Services Accessibility', 'Health Status', 'Home Nursing', 'Humans', 'Male', 'Needs Assessment', '... | 11,833,429 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.100.150', 'N05.300.150'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.318.740.275', 'N05.715.360.750.220... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Disciplines and Occupatio... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The Smart Choices front-of-package nutrition label. Influence on perceptions and intake of cereal. | Numerous front-of-package (FOP) nutrition labeling systems exist, but it is unclear if such labels influence behavior. A single-summary label called Smart Choices (SC) appeared briefly on products in the United States in 2009. The current study aimed to evaluate (1) the influence the SC symbol has on the serving and co... | ['Adolescent', 'Adult', 'Aged', 'Dietary Sucrose', 'Edible Grain', 'Energy Intake', 'Feeding Behavior', 'Female', 'Food Labeling', 'Food Preferences', 'Humans', 'Male', 'Middle Aged', 'Nutritive Value', 'Perception'] | 22,248,710 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D09.301.831.250', 'D09.698.629.305.770.200', 'D09.947.500.250', 'D09.947.750.770.200', 'D27.720.372.300.353.609.750.250', 'G07.203.300.362.831.250', 'G07.203.300.514.500.400.700.750.250', 'J02.500.362.831.250', 'J02.500.514.500.400.700.750.250'], ['A18.024.500.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Cloning of a putative voltage-gated sodium channel from the turbellarian flatworm Bdelloura candida. | The neuromuscular sodium currents of early invertebrates such as platyhelminths display distinctive kinetic and pharmacological properties. We have cloned a cDNA from the horseshoe crab flatworm Bdelloura candida that encodes a protein homologous to the primary subunit of voltage-gated sodium channels. The B. candida p... | ['Amino Acid Sequence', 'Animals', 'Cloning, Organism', 'Decapodiformes', 'Helminth Proteins', 'Horseshoe Crabs', 'Membrane Proteins', 'Molecular Sequence Data', 'Phylogeny', 'Polymerase Chain Reaction', 'Rats', 'Scyphozoa', 'Sequence Alignment', 'Sequence Homology, Amino Acid', 'Sodium Channels', 'Turbellaria'] | 9,300,466 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.393.240', 'E05.820.180'], ['B01.050.500.644.116.150'], ['D12.776.419'], ['B01.050.500.131.450'], ['D12.776.543'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.620.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.50... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Spectrum and functional validation of PSMB5 mutations in multiple myeloma. | Despite an increasing number of approved therapies, multiple myeloma (MM) remains an incurable disease and only a small number of patients achieve prolonged disease control. Some genes have been linked with response to commonly used anti-MM compounds, including immunomodulators (IMiDs) and proteasome inhibitors (PIs). ... | ['Antineoplastic Combined Chemotherapy Protocols', 'Biomarkers, Tumor', 'Boron Compounds', 'Bortezomib', 'Cohort Studies', 'Drug Resistance, Neoplasm', 'Female', 'Follow-Up Studies', 'Gene Expression Regulation, Neoplastic', 'Glycine', 'Humans', 'Male', 'Middle Aged', 'Multiple Myeloma', 'Mutation', 'Neoplasm Recurrenc... | 30,026,573 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D23.101.140'], ['D01.132', 'D02.203'], ['D01.029.260.110.500', 'D01.132.285.500', 'D02.203.200.500', 'D03.383.679.450'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.690.773.984.395'], ['E05.318.372.500.750.249', 'N05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thoracoscopic intracavitary drainage for pneumothorax secondary to bullous emphysema. | Most patients with spontaneous pneumothorax secondary to bullous emphysema are successfully managed by chest-tube drainage. Occasionally a very large air leak prevents full lung expansion. The authors report on a patient in whom thoracoscopic intracavitary drainage of a leaking bulla led to rapid resolution of the pneu... | ['Aged', 'Aged, 80 and over', 'Blister', 'Catheterization', 'Drainage', 'Humans', 'Male', 'Pneumothorax', 'Pulmonary Emphysema', 'Rupture, Spontaneous', 'Thoracoscopy'] | 8,258,136 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C17.800.865.187', 'C23.300.122'], ['E02.148', 'E05.157'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.528.778'], ['C08.381.495.389.750'], ['C23.300.909'], ['E01.370.388.250.840', 'E04.502.250.840', 'E04.928.752']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Diminished influenza A virus-specific MHC class I-restricted cytotoxic T lymphocyte activity among elderly persons. | Influenza A virus-specific MHC class I-restricted cytotoxic T lymphocyte (CTL) activities among young and elderly adults were compared. Peripheral blood lymphocytes from 10 young adults, (mean age 27 +/- 2.4 years) and elderly persons (mean age 71 +/- 1.6 years) were stimulated with influenza A/Taiwan/1/86 (H1N1) virus... | ['Adult', 'Aged', 'Aging', 'Antibodies, Monoclonal', 'Antibodies, Viral', 'Antigens, CD', 'Female', 'Histocompatibility Antigens Class I', 'Humans', 'Immunity, Cellular', 'Immunophenotyping', 'Influenza A virus', 'Leukocyte Count', 'Male', 'T-Lymphocyte Subsets', 'T-Lymphocytes, Cytotoxic'] | 8,476,508 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D12.776.395.550.489', 'D12.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
CTLA-4 Limits Anti-CD20-Mediated Tumor Regression. | PURPOSE: The inhibition of tumor growth by anti-CD20 antibody (Ab) treatment is mediated by Ab- and complement-dependent cytotoxicity in xenograft tumor models. In addition, anti-CD20 therapy for B-cell lymphoma can result in intrinsic and extrinsic tumor resistance to further Ab treatment. However, adaptive immune res... | ['Animals', 'Antibody-Dependent Cell Cytotoxicity', 'Antigen Presentation', 'Antigens, CD20', 'Antineoplastic Agents, Immunological', 'Biomarkers, Tumor', 'CD8-Positive T-Lymphocytes', 'CTLA-4 Antigen', 'Cell Line, Tumor', 'Cross-Priming', 'Cytokines', 'Dendritic Cells', 'Disease Models, Animal', 'Drug Resistance, Neop... | 27,354,469 | [['B01.050'], ['G12.287.070'], ['G12.119', 'G12.450.050.400.070'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120', 'D23.101.100.150.120'], ['D27.505.954.248.384'], ['D23.101.140'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D12.776.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Neutrophil motility in patients with early infection (rapid analysis using automatic image processing system, Magiscan)]. | The authors studied the dependence of blood neutrophil motility on the physical state of patients with infected wounds. Neutrophil motility was recorded and analyzed with the help of Magiscan-2a system of automatic image processing. A special software was developed for monitoring the movement of cells and measuring the... | ['Cell Movement', 'Humans', 'Image Processing, Computer-Assisted', 'Neutrophils', 'Prognosis', 'Wound Infection'] | 1,878,563 | [['G04.198', 'G07.568.500.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['E01.789'], ['C01.947']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Long-term Voice Outcome Following Radiation Versus Laser Microsurgery in Early Glottic Cancer. | OBJECTIVES: Long-term voice outcome (LTVO) after radiation (XRT) or trans-oral laser microsurgery (TLM) is unclear. This study is a multi-modality analysis of LTVO following XRT or TLM in patients with early glottic cancer. We hypothesize that as compared with TLM, LTVO is worse in the XRT group because of progressive ... | ['Aged', 'Aged, 80 and over', 'Dysphonia', 'Female', 'Fibrosis', 'Glottis', 'Humans', 'Laryngeal Neoplasms', 'Laser Therapy', 'Male', 'Microsurgery', 'Middle Aged', 'Neoplasm Staging', 'Radiation Injuries', 'Radiotherapy', 'Risk Factors', 'Squamous Cell Carcinoma of Head and Neck', 'Time Factors', 'Treatment Outcome', ... | 29,229,412 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C08.360.940.325', 'C09.400.940.325', 'C10.597.975.325', 'C23.888.592.979.325'], ['C23.550.355'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['E02.594', 'E04.014.52... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Interpretation of the trace element content of hairs in criminology, toxicology and environmental protection. Experimental migration of metal ions in keratine (author's transl)]. | Metal ions of exogenous origin can penetrate into the hair and can be accumulated. Penetration and distribution of metal ions could be examined by means of electron microprobe-analysis. The dependence of the accumulation of different kations on the concentration of these in the surrounding solutions have been determine... | ['Electron Probe Microanalysis', 'Environmental Pollution', 'Forensic Medicine', 'Germany, West', 'Hair', 'Humans', 'Keratins', 'Osmolar Concentration', 'Trace Elements'] | 71,796 | [['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['N06.850.460'], ['H02.403.330', 'I01.198.780.937'], ['Z01.586.350'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['G02.640'], ['D01.268.811', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Indus... | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
[Physical and aerodynamic airflow relations of the air stream of the Micro-Air aesthesiometer]. | BACKGROUND: In an experimental study we examined the aerodynamical airstreamprofile of a new airstream aesthesiometer. With this instrument it is possible to measure corneal sensitivity without touching the cornea.METHOD: A constant hotwire-anemometer was used to measure the 0.5 s air impulse in different distances. Th... | ['Adult', 'Aged', 'Aged, 80 and over', 'Air', 'Cornea', 'Corneal Diseases', 'Equipment Design', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pain Threshold', 'Reference Values'] | 7,823,522 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G16.500.275.063.150', 'N06.230.300.100.150'], ['A09.371.060.217'], ['C11.204'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593.710.560', 'F02.830.816.444.700', 'G11.561.790.444.700'], ['E05.978.810']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel surgical organ perfusion method for effective ex vivo and in vivo gene transfer into renal glomerular cells. | In an attempt to develop gene therapy for Alport syndrome, we have evaluated surgical methods for gene transfer into pig kidneys. For gene transfer we used an adenovirus expressing the Escherichia coli beta-galactosidase gene as a reporter gene. The viral preparation was first infused in vivo into the porcine renal art... | ['Adenoviridae', 'Animals', 'Coloring Agents', 'Gene Transfer Techniques', 'Genes, Reporter', 'Genetic Therapy', 'Kidney Glomerulus', 'Lac Operon', 'Nephritis, Hereditary', 'Perfusion', 'Renal Artery', 'Swine'] | 10,424,390 | [['B04.280.030'], ['B01.050'], ['D27.720.233'], ['E05.393.350'], ['G05.360.340.024.340.435'], ['E02.095.301', 'E05.393.420.301'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['G05.360.340.024.686.545', 'G05.360.340.358.207.500.545'], ['C12.706.742', 'C12.777.419.570.620', 'C13.351.875.742', 'C13.351.968.419.570.620... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental impacts of cooling system on Abou Qir Bay. | This study was conducted to evaluate the impacts of cooling water on cooling system of Abou Qir Power Plant and on the receiving Abou Qir Bay. Abou Qir Power Plant is a conventional steam electric power plant located in Alexandria Governorate, Egypt. Water and biota samples were collected monthly from cooling water and... | ['Chromatography, Gas', 'Egypt', 'Environmental Monitoring', 'Humans', 'Hydrogen-Ion Concentration', 'Mass Spectrometry', 'Neutron Activation Analysis', 'Power Plants', 'Seasons', 'Seawater', 'Temperature', 'Water', 'Water Pollution'] | 17,187,744 | [['E05.196.181.349'], ['Z01.058.266.317'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.196.566'], ['E05.196.039.564'], ['J01.780', 'J03.540.680'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G16.500.275.725.500'], ['G01.906... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
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