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Force-sensing microprobe for precise stimulation of mechanosensitive tissues. | Quantitative study of the transduction mechanisms in mechanically sensitive nerve terminals has been impeded by the lack of instrumentation with which to generate precisely controlled, physically localized mechanical stimuli. We have developed high-resolution force sensing mechanical microprobes for use in the characte... | ['Animals', 'Cornea', 'In Vitro Techniques', 'Mechanoreceptors', 'Physical Stimulation', 'Rabbits'] | 7,642,187 | [['B01.050'], ['A09.371.060.217'], ['E05.481'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['E05.723'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phosphorylation of hydroxylysine residues in collagen synthesized by cultured aortic smooth muscle cells. | O5-Phosphohydroxylysine was chemically synthesized and techniques were established for its identification by combined use of cation-exchange chromatography, thin-layer electrophoresis at pH 1.9 and 3.5, and thin-layer chromatography. Clean separation of phosphohydroxylysine from the other phospho amino acids, phosphoet... | ['Acids', 'Animals', 'Aorta', 'Cattle', 'Cells, Cultured', 'Collagen', 'Hydrolysis', 'Hydroxylysine', 'Isoelectric Point', 'Muscle, Smooth, Vascular', 'Phosphorylation', 'Protein Kinases', 'Protein Processing, Post-Translational'] | 3,858,806 | [['D01.029'], ['B01.050'], ['A07.015.114.056'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G02.380'], ['D12.125.068.555.478', 'D12.125.095.647.478'], ['E05.301.300.663.500', 'G02.300.500'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['G02.111.665'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exploratory thoracotomy and its influence on the survival of patients with lung cancer. | PURPOSE: To evaluate diagnostic procedures, reasons for exploratory thoracotomy (ET), causes of unresectability of lung cancer, possibility for reducing numbers of ETs, and the influence of ET on survival.PATIENTS AND METHODS: Between 1990 and 1999, 1808 patients with lung cancer were operated on. ET was performed in 1... | ['Adrenal Gland Neoplasms', 'Adult', 'Aged', 'Aged, 80 and over', 'Chi-Square Distribution', 'Female', 'Humans', 'Lung', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Radiography, Thoracic', 'Survival Analysis', 'Thoracotomy', 'Tomography, X-Ray Computed'] | 16,957,979 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.5... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Choline alkylsulfates--new promising green surfactants. | In this work we show how a new promising green and highly water-soluble surfactant can be designed based on recent progress in the knowledge of counterion-headgroup binding and crystallization behavior. The result is the combination of a most classical surfactant anion, dodecylsulfate (DS), with choline (Ch), a natural... | ['Alkanesulfonic Acids', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Proliferation', 'Choline', 'Dose-Response Relationship, Drug', 'Drug Screening Assays, Antitumor', 'HeLa Cells', 'Humans', 'Structure-Activity Relationship', 'Surface-Active Agents'] | 23,200,100 | [['D02.455.326.146.100', 'D02.886.645.600.055'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.388', 'E05.200.500.388... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
IFN-alpha/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis. | The antiviral activities of type I IFNs have long been established. However, comparatively little is known of their role in defenses against nonviral pathogens. We examined here the effects of type I IFNs on host resistance against the model pathogenic yeast Cryptococcus neoformans. After intratracheal or i.v. challeng... | ['Animals', 'Cells, Cultured', 'Cryptococcosis', 'Dendritic Cells', 'Disease Models, Animal', 'Interferon-alpha', 'Interferon-beta', 'Macrophages', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Receptor, Interferon alpha-beta', 'Signal Transduction', 'Survival Rate'] | 18,566,423 | [['B01.050'], ['A11.251'], ['C01.150.703.248'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.250'], ['D12.644.276.374.440.890.275', 'D12.776.467.374.440.890.275', '... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Portable antiquities: transporation, ruins, and communications in nineteenth-century archeology]. | The article addresses an issue in nineteenth-century archeology: the transformation of ancient American ruins into scientific evidence. It focuses specifically on the case of Palenque, a city discovered in the jungle in the late eighteenth century. The archeological exploration of this find, which occurred shortly afte... | ['Americas', 'Archaeology', 'History, 19th Century', 'Mexico'] | 19,241,715 | [['Z01.107'], ['I01.076.201.208'], ['K01.400.504.937'], ['Z01.107.567.589']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Extracorporeal Transseptal Penile Prosthesis Implantation for Extreme Cases of Corporeal Fibrosis: Shaeer Implantation Technique. | BACKGROUND: Penile prosthesis implantation into scarred corporeal bodies is one of the most challenging procedures in prosthetic urologic surgery, especially following infection and extrusion of a penile implant. Several instruments and techniques have been used for making dilatation of scarred corporeal bodies easier ... | ['Adult', 'Fibrosis', 'Humans', 'Male', 'Penile Implantation', 'Penile Prosthesis', 'Penis', 'Salvage Therapy'] | 30,057,279 | [['M01.060.116'], ['C23.550.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.650.620', 'E04.950.774.860.620'], ['E07.695.610'], ['A05.360.444.492'], ['E02.895']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of an encystation-specific transcription factor, Myb protein in Giardia lamblia. | The life cycle of Giardia lamblia contains two differentiation processes, encystation and excystation. We performed an experiment to identify the genes induced during encystation using the differential display reverse transcriptase-polymerase chain reaction. Three of twelve isolated cDNA clones that showed increased tr... | ['Animals', 'Base Sequence', 'Cloning, Molecular', 'Giardia lamblia', 'Molecular Sequence Data', 'Protozoan Proteins', 'RNA, Protozoan', 'Recombinant Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Trans-Activators'] | 12,742,583 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B01.237.385.400'], ['L01.453.245.667'], ['D12.776.820'], ['D13.444.735.650'], ['D12.776.828'], ['E05.393.620.500.725'], ['D12.776.260.755', 'D12.776.930.900', 'D12.776.964.925.984']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Sclerosing encapsulating peritonitis as a complication of long-term continuous ambulatory peritoneal dialysis in Korea. | Sclerosing encapsulating peritonitis (SEP) is a rare yet serious complication in patients with continuous ambulatory peritoneal dialysis (CAPD). Incidence and prevalence of this syndrome have been defined in some large populations and a few single-centre experiences, but there is no satisfactory estimate of the compara... | ['Adult', 'Female', 'Humans', 'Incidence', 'Korea', 'Male', 'Peritoneal Dialysis, Continuous Ambulatory', 'Peritonitis', 'Prevalence', 'Risk Factors', 'Sclerosis'] | 15,012,689 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.252.474.557', 'Z01.586.407'], ['E02.760.106.500', 'E02.870.300.650.500', 'E02.912.800.650.500', 'N02.421.585.106.500'], ['C01.463.600... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Role of ABCB1 and ABCG2 in the multidrug resistance of hypopharyngeal carcinoma FaDu cell line]. | OBJECTIVE: To investigate the expression of multidrug resistance gene ABCB1 and ABCG2 in FaDu cells (human hypopharyngeal carcinoma cell line) and the multidrug resistance (MDR) cell lines FaDu/T transformed from FaDu cells by taxol and underlying mechanisms of MDR.METHODS: The multidrug resistance sensitivities of FaD... | ['ATP Binding Cassette Transporter, Subfamily B', 'ATP Binding Cassette Transporter, Subfamily B, Member 1', 'ATP Binding Cassette Transporter, Subfamily B, Member 2', 'ATP-Binding Cassette Transporters', 'Cell Line, Tumor', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Humans', 'Hypopharyngeal Neoplasms'] | 22,800,348 | [['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dizepam metabolism in human foetal and adult liver. | Diazepam was metabolized by human foetal liver microsomes to N-desmethyldiazepam and N-methyloxazepam as early as the 13th week of gestation. The metabolic activity was lower than that of microsomes from adult human liver. Diazepam was shown mainly to be hydroxylated to N-methyloxazepam at substrate concentrations high... | ['Aging', 'Carbon Monoxide', 'Dealkylation', 'Depression, Chemical', 'Diazepam', 'Female', 'Fetus', 'Gestational Age', 'Humans', 'Hydroxylation', 'In Vitro Techniques', 'Liver', 'Microsomes, Liver', 'Pregnancy', 'Proadifen', 'Spectrophotometry', 'Time Factors'] | 832,657 | [['G07.345.124'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['G02.111.188', 'G02.607.141', 'G03.219'], ['G07.690.773.750'], ['D03.633.100.079.080.070.216'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.385', 'G02.607.348', 'G03.425'], ['E05... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oncological outcome after radical prostatectomy: Marital status does not make a difference. | OBJECTIVES: To examine the impact of marital status on prostate cancer characteristics at radical prostatectomy and oncological outcome after surgery at a high-volume center.METHODS: We relied on the Martini-Clinic Prostate Cancer database and investigated 8088 prostate cancer patients treated with radical prostatectom... | ['Humans', 'Male', 'Marital Status', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Propensity Score', 'Prostate', 'Prostatectomy', 'Prostatic Neoplasms', 'Regression Analysis', 'Survival Analysis', 'Treatment Outcome'] | 25,781,055 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500', 'I01.240.361.500', 'I01.880.853.150.423.500', 'N01.224.361.500', 'N01.824.308.500'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['C04.697.650', 'C23.550.727.650'], ['C04.697.655', 'C23.550.... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis. | The potassium channel Kv1.3 plays roles in immunity, neuronal development and sensory discrimination. Regulation of Kv1.3 by kinase signaling has been studied. In this context, EGF binds to specific receptors (EGFR) and triggers tyrosine kinase-dependent signaling, which down-regulates Kv1.3 currents. We show that Kv1.... | ['Animals', 'Butadienes', 'Cells, Cultured', 'Clathrin', 'Down-Regulation', 'Dynamin II', 'Endocytosis', 'Epidermal Growth Factor', 'ErbB Receptors', 'HEK293 Cells', 'HeLa Cells', 'Humans', 'Kv1.3 Potassium Channel', 'Lateral Ventricles', 'Mice', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3... | 26,542,799 | [['B01.050'], ['D02.455.326.271.665.146.240'], ['A11.251'], ['D12.776.543.990.200'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D08.811.277.040.330.200.200', 'D12.776.220.600.450.200.200', 'D12.776.543.990.400.200'], ['G04.417'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Blur adaptation: contrast sensitivity changes and stimulus extent. | A prolonged exposure to foveal defocus is well known to affect the visual functions in the fovea. However, the effects of peripheral blur adaptation on foveal vision, or vice versa, are still unclear. In this study, we therefore examined the changes in contrast sensitivity function from baseline, following blur adaptat... | ['Adaptation, Ocular', 'Adult', 'Contrast Sensitivity', 'Female', 'Fovea Centralis', 'Humans', 'Male', 'Myopia', 'Psychophysics', 'Sensory Thresholds', 'Visual Fields', 'Young Adult'] | 25,817,716 | [['G14.020'], ['M01.060.116'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['A09.371.729.522.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.744.636'], ['E01.370.685', 'F04.096.753'], ['F02.463.593.710'], ['F02.463.593.932.934', ... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increased expression of 11 beta-hydroxysteroid dehydrogenase type 2 in the lungs of patients with acute respiratory distress syndrome. | We examined the immunohistochemical distribution of 11 beta-hydroxysteroid dehydrogenase type 2 (11 beta-HSD2), the enzyme responsible for the conversion of bioactive glucocorticoids to their receptor-inactive forms, in lung tissue obtained at autopsy from 14 patients who had died due to acute respiratory distress synd... | ['11-beta-Hydroxysteroid Dehydrogenase Type 2', 'Adult', 'Aged', 'Aged, 80 and over', 'Autopsy', 'Female', 'Humans', 'Immunohistochemistry', 'Lung', 'Male', 'Middle Aged', 'Respiratory Distress Syndrome'] | 14,629,298 | [['D08.811.682.047.436.174.600', 'D08.811.682.047.820.100.600'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.5... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Mourning the body as bedrock: developmental considerations in treating transsexual patients analytically. | This paper introduces the concept of massive gender trauma, a clinical syndrome arising at the onerous intersection of the misgendering of transgender patients and the subjective, anguished experience of the natal body. Analysts have become increasingly aware in recent years of the complex interactions between psyche, ... | ['Child, Preschool', 'Female', 'Grief', 'Humans', 'Male', 'Psychoanalytic Therapy', 'Sexual Behavior', 'Transsexualism'] | 25,277,869 | [['M01.060.406.448'], ['F01.470.142.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.754.709'], ['F01.145.802'], ['F01.145.802.975.750']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
De Novo incontinentia pigmenti in female twins. | The cutaneous lesions of incontinentia pigmenti classically evolve in stages, beginning with erythematous vesicular rash and bullae, followed by verrucose lesions, with an eventual macular pattern of splashed or whorled hyperpigmentation. We describe female twins presenting with the classic form of cutaneous expression... | ['Carrier Proteins', 'Female', 'Genetic Diseases, X-Linked', 'Humans', 'I-kappa B Kinase', 'Incontinentia Pigmenti', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Mutation', 'Pedigree', 'Polymerase Chain Reaction', 'Twins'] | 15,493,740 | [['D12.776.157'], ['C16.320.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['C16.131.077.445', 'C16.131.831.580', 'C16.320.850.420', 'C17.800.621.497', 'C17.800.804.580', 'C17.800.827.420'], ['M01.060.703.520'], ['M01.060.703.520.520'],... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Kinetic peculiarities of human tissue kallikrein: 1--substrate activation in the catalyzed hydrolysis of H-D-valyl-L-leucyl-L-arginine 4-nitroanilide and H-D-valyl-L-leucyl-L-lysine 4-nitroanilide; 2--substrate inhibition in the catalyzed hydrolysis of N alpha-p-tosyl-L-arginine methyl ester. | Hydrolysis of D-valyl-L-leucyl-L-lysine 4-nitroanilide (1), D-valyl-L-leucyl-L-arginine 4-nitroanilide (2), and N alpha-p-tosyl-L-arginine methyl ester (3) by human tissue kallikrein was studied throughout a wide range of substrate concentrations. At low substrate concentrations, the hydrolysis followed Michaelis-Mente... | ['Catalysis', 'Chromogenic Compounds', 'Humans', 'Hydrolysis', 'Kallikreins', 'Kinetics', 'Models, Chemical', 'Oligopeptides', 'Protein Binding', 'Substrate Specificity', 'Tosylarginine Methyl Ester'] | 11,913,965 | [['G02.130'], ['D27.720.233.174', 'D27.720.470.410.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['D08.811.277.656.300.760.442', 'D08.811.277.656.959.350.442', 'D12.776.124.125.597', 'D23.119.597'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['D12.644.456'], ['G02.111.679', 'G03.808'], ['G0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences. | The prominent role of antiviral cytotoxic CD8(+) T-lymphocytes (CD8-TL) in containing the acute viremia of human and simian immunodeficiency viruses (HIV-1 and SIV) has rationalized the development of T-cell-based vaccines. However, the presence of escape mutations in the acute stage of infection has raised a concern t... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Viral', 'Antigens, Viral', 'CD8-Positive T-Lymphocytes', 'Epitopes', 'Founder Effect', 'Immune Evasion', 'Immunity, Cellular', 'Macaca', 'Models, Immunological', 'Models, Theoretical', 'Simian Acquired Immunodeficiency Syndrome', 'Simian Immunodeficiency Virus'] | 20,335,256 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.327'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D23.050.550'], ['G05.285'], ['G06.462.400', 'G12.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Modeling radon entry into Florida slab-on-grade houses. | Radon entry into a Florida house whose concrete slab is supported by a permeable concrete-block stem wall and a concrete footer is modeled. The slab rests on backfill material; the same material is used to fill the footer trench. A region of undisturbed soil is assumed to extend 10 m beyond and below the footer. The so... | ['Air Pollution, Indoor', 'Air Pollution, Radioactive', 'Architecture', 'Florida', 'Housing', 'Humans', 'Models, Structural', 'Radon'] | 8,376,117 | [['N06.850.460.100.080'], ['N06.850.460.100.110', 'N06.850.810.080'], ['J01.086'], ['Z01.107.567.875.750.350'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['D01.268.271.800', 'D01.268.613.... | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Discovery of novel acetanilide derivatives as potent and selective beta3-adrenergic receptor agonists. | In the search for potent and selective human beta3-adrenergic receptor (AR) agonists as potential drugs for the treatment of obesity and noninsulin-dependent (type II) diabetes, a novel series of acetanilide-based analogues were prepared and their biological activities were evaluated at the human beta3-, beta2-, and be... | ['Acetanilides', 'Adrenergic beta-1 Receptor Agonists', 'Adrenergic beta-2 Receptor Agonists', 'Adrenergic beta-3 Receptor Agonists', 'Crystallography, X-Ray', 'Dose-Response Relationship, Drug', 'Drug Design', 'Humans', 'Models, Molecular', 'Molecular Conformation', 'Pyrazines', 'Pyridines', 'Pyrimidines', 'Stereoisom... | 19,232,786 | [['D02.065.199.092', 'D02.092.146.113.092'], ['D27.505.519.625.050.100.200.100', 'D27.505.696.577.050.100.200.100'], ['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['D27.505.519.625.050.100.200.300', 'D27.505.696.577.050.100.200.300'], ['E05.196.309.742.225'], ['G07.690.773.875', 'G07.690.936.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[The absence of interference between GSM mobile telephones and implantable defibrillators: an in-vivo study. Groupe Syst?mes Mobiles]. | INTRODUCTION AND OBJECTIVES: The electromagnetic field created by mobile telephones can cause pacemaker dysfunction. Although implantable cardioverter defibrillators are also susceptible to electromagnetic interference, few studies have addressed this issue and compatibility with the GSM mode has not been tested. This ... | ['Defibrillators, Implantable', 'Electrocardiography', 'Electromagnetic Fields', 'Equipment Design', 'Equipment Failure', 'Humans', 'Risk Factors', 'Telephone'] | 9,417,561 | [['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E01.370.370.380.240', 'E01.370.405.240'], ['G01.358.500.260', 'G01.358.750.500'], ['E05.320'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.49... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Identification of heat stable protease of Klebsiella oxytoca isolated from raw milk. | AIMS: The aim of this study was to identify and characterize heat stable proteinases of psychrotrophic proteolytic bacteria isolated from raw milk.METHODS AND RESULTS: A strain of Klebsiella oxytoca producing a high proteolytic activity when cultured on milk was isolated. Maximum proteolytic activity was observed at th... | ['Animals', 'Enzyme Stability', 'Food Microbiology', 'Hydrogen-Ion Concentration', 'Klebsiella oxytoca', 'Milk', 'Peptide Hydrolases', 'Temperature'] | 14,746,547 | [['B01.050'], ['E05.916.360', 'G02.111.700.500'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['G02.300'], ['B03.440.450.425.425.580', 'B03.660.250.150.400.580'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525',... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Comparison of Composer and ORCHESTRAR. | Although the number of known protein structures is increasing, the number of protein sequences without determined structures is still much larger. Three-dimensional (3D) protein structure information helps in the understanding of functional mechanisms, but solving structures by X-ray crystallography or NMR is often a l... | ['Algorithms', 'Computer Simulation', 'Models, Molecular', 'Protein Conformation', 'Proteins', 'Sequence Alignment', 'Software', 'Structural Homology, Protein'] | 18,361,454 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E05.599.595'], ['G02.111.570.820.709'], ['D12.776'], ['E05.393.751'], ['L01.224.900'], ['G02.111.570.820.709.805', 'G02.111.810.200.820', 'G05.820']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Serum anti-tropo:anti-alpha-elastin antibody ratio assessing elastin turnover in scleroderma. | Serum antibodies to native (tropo) and denatured (alpha) elastins appear to correlate with the production and breakdown respectively of elastic tissue. Elastin may be degraded as a part of autoimmune diseases. This possibility was tested by measuring IgG antibodies to tropo- and alpha-elastins by ELISA in the sera of 1... | ['Adolescent', 'Adult', 'Antibodies', 'Connective Tissue Diseases', 'Elastin', 'Humans', 'Immunoglobulin G', 'Middle Aged', 'Scleroderma, Systemic', 'Tropoelastin'] | 1,617,894 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C17.300'], ['D05.750.078.421', 'D12.776.860.300.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reduced colonization of newborns with group B streptococci following washing of the birth canal with chlorhexidine. | Possible measures for prevention of neonatal group B streptococcal (GBS) septicemia include active or passiv immunoprophylaxis and administration of penicillin to mothers and infants. In a previous study we have found GBS to be extremely sensitive to chlorhexidine. Furthermore vaginal washing with chlorhexidine diminis... | ['Cervix Uteri', 'Chlorhexidine', 'Female', 'Humans', 'Infant, Newborn', 'Streptococcal Infections', 'Streptococcus agalactiae', 'Vagina', 'Vulva'] | 3,910,791 | [['A05.360.319.679.256'], ['D02.078.370.141.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C01.150.252.410.890'], ['B03.353.750.737.872.100', 'B03.510.400.800.872.100', 'B03.510.550.737.872.100'], ['A05.360.319.779'], ['A05.360.319.887']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Scorpion envenomation treated in the Infectious and Tropical Diseases at the Donka National Hospital, Guinea]. | A retrospective descriptive study was conducted from 1(st) October 2010 to 30 November 2012 on the records of patients admitted for scorpion envenomation in the Department of Infectious and Tropical Diseases at the Donka National Hospital. The objective of this study is to describe the epidemiological profile and clini... | ['Adolescent', 'Adrenal Cortex Hormones', 'Adult', 'Analgesics', 'Animals', 'Anti-Bacterial Agents', 'Antitoxins', 'Child', 'Combined Modality Therapy', 'Female', 'Furosemide', 'Guinea', 'Hospitals, Public', 'Humans', 'Male', 'Medicine, African Traditional', 'Retrospective Studies', 'Scorpion Stings', 'Scorpions', 'Sym... | 25,158,841 | [['M01.060.057'], ['D06.472.040'], ['M01.060.116'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.954.122.085'], ['D12.776.124.486.485.114.573.601', 'D12.776.124.790.651.114.573.601', 'D12.776.377.715.548.114.573.601', 'D20.215.401.601'], ['M01.060.406'], ['E02.186'], ['D02.065.884.725.300'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Is there an unusual incidence of the manifestation of intracranial angiomas in pregnancy? Risk assessment based on 17,733 patients over 10 years]. | From 1979-1988, 134 inpatients (m:f = 80:54) were treated because of an intracranial angioma (AVM). The male/female ratio was 3/2 in general as well as during the "reproductive age" (15-45 yrs). In 6 patients (20-27 yrs; grav 2/para 1: n = 3; grav 1/para 0: n = 3) the AVM became symptomatic during pregnancy (n = 4: 23-... | ['Adolescent', 'Adult', 'Aged', 'Brain Neoplasms', 'Child', 'Cross-Sectional Studies', 'Female', 'Germany', 'Hemangioma', 'Humans', 'Incidence', 'Middle Aged', 'Pregnancy', 'Pregnancy Complications, Neoplastic'] | 1,595,319 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.315'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
D-Penturonic acids: solution studies of stable-isotopically enriched compounds by 1H- and 13C-n.m.r. spectroscopy. | Methyl D-pentofuranosides were prepared by Fischer glycosidation of the aldopentoses D-arabinose, D-lyxose, D-ribose, D-xylose, and 2-deoxy-D-erythro-pentose, and oxidized with O2 over a platinum oxide catalyst to give the corresponding methyl D-pentofuranosiduronic acids. After purification by anion-exchange chromatog... | ['Carbon Isotopes', 'Catalysis', 'Glycosides', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Magnetic Resonance Spectroscopy', 'Oxidation-Reduction', 'Protons', 'Solutions', 'Structure-Activity Relationship', 'Uronic Acids'] | 1,652,354 | [['D01.268.150.075', 'D01.496.123'], ['G02.130'], ['D09.408'], ['G02.300'], ['G02.380'], ['E05.196.867.519'], ['G02.700', 'G03.295.531'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D26.776'], ['G02.111.830', 'G07.690.773.997'], ['D02.241.081.844.915', 'D02.241.152.811', 'D02... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of short-term memory capacity and task experience for overconfidence in judgment under uncertainty. | Research with general knowledge items demonstrates extreme overconfidence when people estimate confidence intervals for unknown quantities, but close to zero overconfidence when the same intervals are assessed by probability judgment. In 3 experiments, the authors investigated if the overconfidence specific to confiden... | ['Adult', 'Concept Formation', 'Female', 'Humans', 'Intuition', 'Judgment', 'Male', 'Memory, Short-Term', 'Probability Learning', 'Problem Solving', 'Serial Learning', 'Uncertainty'] | 18,763,889 | [['M01.060.116'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.188.675'], ['F02.463.785.626'], ['F02.463.425.540.407'], ['F02.463.425.701'], ['F02.463.425.725', 'F02.463.785.810'], ['F02.463.425.952.747'], ['E05.318.740.600.900', 'F02.463.785.373.820', 'G17.680.875', 'N05.715.360.750.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Deprivation of Liberty Safeguards: observations and limitations. | The recently introduced Deprivation of Liberty Safeguards (DoLS), which came into force in April 2009, was created to protect the liberty of people lacking capacity admitted to care homes and hospitals in England and Wales. This paper discusses observations and some limitations of the DoLS for protecting the liberty of... | ['Civil Rights', 'Commitment of Mentally Ill', 'Humans', 'Mental Competency', 'Patient Advocacy', 'Patient Rights', 'United Kingdom'] | 22,021,586 | [['I01.880.604.473.352', 'N03.706.437.352'], ['F04.096.544.335.200', 'N03.706.535.351.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.590', 'F02.410', 'I01.880.604.583.530', 'N03.706.535.625'], ['I01.880.604.631', 'N03.706.678'], ['I01.880.604.473.650', 'N03.706.437.650'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Reproductive endocrine effects of acute exposure to toluene in men and women. | OBJECTIVES: Despite observation of adverse reproductive effects of toluene, including alterations of serum gonadotropins (luteinising hormone (LH) and follicle stimulating hormone (FSH)) in humans, little is known of the mechanism of toxicity. The hypothesis was tested that toluene acutely suppresses pulsatile gonadotr... | ['Adult', 'Analysis of Variance', 'Biomarkers', 'Environmental Exposure', 'Female', 'Follicle Stimulating Hormone', 'Follicular Phase', 'Gonadotropin-Releasing Hormone', 'Humans', 'Luteal Phase', 'Luteinizing Hormone', 'Male', 'Sex Factors', 'Toluene'] | 10,658,543 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D23.101'], ['N06.850.460.350'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['G08.686.605.310'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.36... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparative evolution of mipafox-induced delayed neuropathy in rats and hens. | Adult male Long-Evans rats and White Leghorn hens were given 30 mg/kg mipafox ip. Administration of this organophosphorus ester resulted in > or = 89% inhibition of brain and spinal cord neurotoxic esterase activity in both species 4 hr after dosing. Our sequential, comparative study of the bilateral mipafox-induced ne... | ['Animals', 'Carboxylic Ester Hydrolases', 'Chickens', 'Disease Models, Animal', 'Female', 'Isoflurophate', 'Male', 'Nervous System Diseases', 'Rats', 'Species Specificity'] | 1,302,299 | [['B01.050'], ['D08.811.277.352.100'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.705.429.750.249'], ['C10'], ['B01.050.150.900.649.313.992.635.505.700'], ['G16.824']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer. | Background: Triple-negative breast cancer (TNBC), lacking expression of hormone and human epidermal growth factor receptor 2 receptors, is an aggressive subtype that frequently metastasizes to the brain and has no FDA-approved systemic therapies. Previous literature demonstrates mitogen-activated protein kinase kinase ... | ['Animals', 'Apoptosis', 'Brain Neoplasms', 'Cell Proliferation', 'Drug Synergism', 'Female', 'Humans', 'MAP Kinase Kinase 1', 'MAP Kinase Kinase 2', 'Mice', 'Phosphoinositide-3 Kinase Inhibitors', 'Phosphorylation', 'Protein Kinase Inhibitors', 'Receptor, Platelet-Derived Growth Factor alpha', 'Receptor, Platelet-Deri... | 28,486,691 | [['B01.050'], ['G04.146.954.035'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.968.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.565.100', 'D08.811.913.696.620.682.725.200.100', 'D12.644.360.440.100', 'D12.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Iron deficiency: diagnosis and treatment. | Mild iron deficiency is common among infants, adolescents and women during the childbearing years. Practical and economical approaches toward its identification, treatment and prevention are needed. Laboratory screening is based on hemoglobin or hematocrit determinations compared with age-specific and sex-specific refe... | ['Adolescent', 'Adult', 'Anemia, Hypochromic', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged'] | 7,257,364 | [['M01.060.057'], ['M01.060.116'], ['C15.378.071.196'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prediction of community prevalence of human onchocerciasis in the Amazonian onchocerciasis focus: Bayesian approach. | OBJECTIVE: To develop a Bayesian hierarchical model for human onchocerciasis with which to explore the factors that influence prevalence of microfilariae in the Amazonian focus of onchocerciasis and predict the probability of any community being at least mesoendemic (>20% prevalence of microfilariae), and thus in need ... | ['Adolescent', 'Adult', 'Animals', 'Anthelmintics', 'Bayes Theorem', 'Cluster Analysis', 'Female', 'Humans', 'Ivermectin', 'Male', 'Onchocerciasis', 'Prevalence', 'Residence Characteristics', 'Venezuela'] | 12,973,640 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D27.505.954.122.250.075'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540.576.500.997'], ['C01.610.335.508.700.7... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hamster growth hormone. Species specificity and physiological changes in blood and pituitary concentrations as measured by a homologous radioimmunoassay. | A specific and sensitive homologous radioimmunoassay (RIA) for determination of golden hamster growth hormone (GH) is described and compared to a heterologous hamster GH RIA. Using the homologous system, cross-reactivity experiments between golden hamster GH on one hand, and pituitary extracts from two other hamster sp... | ['Animals', 'Antibody Specificity', 'Circadian Rhythm', 'Cricetinae', 'Epitopes', 'Female', 'Food', 'Growth Hormone', 'Humans', 'Male', 'Mesocricetus', 'Pituitary Gland', 'Radioimmunoassay', 'Rats', 'Species Specificity', 'Starvation', 'Stress, Physiological'] | 6,183,612 | [['B01.050'], ['G12.100'], ['G07.180.562.190'], ['B01.050.150.900.649.313.992.635.075.250'], ['D23.050.550'], ['G07.203.300', 'J02.500'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['A06.300.747', 'A06.688.357... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fruit and vegetable availability and selection: federal food package revisions, 2009. | BACKGROUND: With nearly 49,000 authorized retailers nationwide, a policy change that added fruits and vegetables (FV) to the U.S. Department of Agriculture's Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) food packages in 2009 had the potential to expand neighborhood FV availability.PURPO... | ['African Americans', 'Commerce', 'Feeding Behavior', 'Food Assistance', 'Food Packaging', 'Food Supply', 'Fruit', 'Humans', 'Illinois', 'Poverty', 'Regression Analysis', 'Residence Characteristics', 'Socioeconomic Factors', 'United States', 'United States Department of Agriculture', 'Vegetables'] | 22,992,361 | [['M01.686.508.100.100', 'M01.686.754.100'], ['J01.219'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['I01.880.787.839.500', 'N03.219.521.346.506.281'], ['J01.576.423.200.375', 'J01.576.423.850.600', 'J01.576.761.400'], ['J01.576.423.750'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.050.150.90... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, an... | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Fibrous membrane formation at the capsular margin in capsule contraction syndrome. | PURPOSE: To determine whether the pathogenesis of capsule contraction syndrome involves the outgrowth of the fibrous membrane from the anterior capsule margin.SETTING: Department of Ophthalmology, Keio University School of Medicine, Tokyo, and the Ando Eye Clinic, Kanagawa, Japan.METHODS: A retrospective review of medi... | ['Actins', 'Adult', 'Aged', 'Aged, 80 and over', 'Capsulorhexis', 'Cell Division', 'Epithelium', 'Female', 'Fibrosis', 'Humans', 'Laser Therapy', 'Lens Capsule, Crystalline', 'Male', 'Middle Aged', 'Phacoemulsification', 'Postoperative Complications', 'Retrospective Studies', 'Syndrome'] | 10,404,367 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.540.825.249.352'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A10.272'], ['C23.550.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.5... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells. | Peripheral T-cell tolerance is thought to significantly contribute to the prevention of autoimmunity, and it has been shown that antigen-presenting steady-state dendritic cells efficiently induce peripheral tolerance. We previously showed that dendritic-cell-induced tolerance is a T-cell-intrinsic process that depends ... | ['Animals', 'Antigens, CD', 'CD8-Positive T-Lymphocytes', 'CTLA-4 Antigen', 'Dendritic Cells', 'Forkhead Transcription Factors', 'Immune Tolerance', 'Interleukin-10', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Phenotype', 'T-Lymphocytes, Regulatory'] | 20,018,763 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D12.776.465.782', 'D12.776.543.750.705.222.750', 'D23.050.301.264.894.158', 'D23.101.100.894.158'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.67... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of acute and chronic morphine dependence in male and female mice. | The present study compared male and female mice for frequency of naloxone-precipitated jumping and naloxone ED(50) values, two common indices of physical dependence, following acute and chronic morphine administration. Both sexes displayed a positive dose-response relationship between acute morphine and naloxone doses ... | ['Animals', 'Dose-Response Relationship, Drug', 'Female', 'Male', 'Mice', 'Morphine', 'Morphine Dependence', 'Motor Activity', 'Naloxone', 'Narcotic Antagonists', 'Narcotics', 'Sex Factors', 'Substance Withdrawal Syndrome'] | 11,566,152 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['C25.775.643.500.600', 'F03.900.647.500.600'], ['F01.145.632', 'G11.427.410.698'], ['D03.132.577.249.706', 'D03.60... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Investigating the salinization and freshening processes of coastal groundwater resources in Urmia aquifer, NW Iran. | This paper presents the results of an assessment about interaction between Urmia Lake (UL) and coastal groundwater in the Urmia aquifer (UA). This aquifer is the most significant contributor to the freshwater supply of the coastal areas. The use of hydrochemical facies can be very useful to identify the saltwater encro... | ['Chlorides', 'Environmental Monitoring', 'Groundwater', 'Iran', 'Salinity', 'Sulfates', 'Water Pollutants', 'Water Supply'] | 27,000,318 | [['D01.210.450.150', 'D01.248.497.158.215'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.355'], ['Z01.252.245.500.350'], ['G02.640.500'], ['D01.248.497.158.845', 'D01.875.800.800.850'], ['D27.888.284.903'], ['J01.293.821.500']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Effects of different doses of physical activity on cardiorespiratory fitness among sedentary, overweight or obese postmenopausal women with elevated blood pressure: a randomized controlled trial. | CONTEXT: Low levels of cardiorespiratory fitness are associated with high risk of mortality, and improvements in fitness are associated with reduced mortality risk. However, a poor understanding of the physical activity-fitness dose response relation remains.OBJECTIVE: To examine the effect of 50%, 100%, and 150% of th... | ['Aged', 'Blood Pressure', 'Energy Metabolism', 'Exercise', 'Female', 'Heart Rate', 'Humans', 'Hypertension', 'Middle Aged', 'Obesity', 'Overweight', 'Oxygen Consumption', 'Physical Fitness', 'Postmenopause', 'Rest'] | 17,507,344 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G03.295'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.69... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Medical diagnoses of heat wave-related hospital admissions in older adults. | Heat waves have been associated with adverse human health effects, including higher rates of all-cause and cardiovascular mortality, and these health effects may be exacerbated under continued climate change. However, specific causes of hospitalizations associated with heat waves have not been characterized on a nation... | ['Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Chronic Disease', 'Climate Change', 'Female', 'Hospitalization', 'Hot Temperature', 'Humans', 'Male', 'Medicare', 'Public Health', 'Risk Factors', 'United States'] | 29,428,173 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['C23.550.291.500'], ['G16.500.175.374'], ['E02.760.400', 'N02.421.585.400'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
[A preliminary study on the measurement of (1,3)-â-D-glucan in bronchoalveolar lavage for the diagnosis of pulmonary fungal infections]. | OBJECTIVE: To explore the measurement of (1,3)-â-D-glucan bronchoalveolar lavage fluid (BALF) for the diagnosis of pulmonary fungal infections.METHODS: A total of 135 patients in the General Hospital of Tianjin Medical University from February 2010 to February 2011 were enrolled. There were 34 cases of confirmed or cli... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bronchoalveolar Lavage Fluid', 'Case-Control Studies', 'Female', 'Humans', 'Lung Diseases, Fungal', 'Male', 'Middle Aged', 'Young Adult', 'beta-Glucans'] | 23,328,179 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.927.100.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.703.534', 'C01.748.435', 'C08.381.472', 'C08.730.435'], ['M01.060.116.630'], ['M... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Medical Equipment Maintenance Methods]. | Due to the high technology and the complexity of medical equipment, as well as to the safety and effectiveness, it determines the high requirements of the medical equipment maintenance work. This paper introduces some basic methods of medical instrument maintenance, including fault tree analysis, node method and exclus... | ['Equipment and Supplies, Hospital', 'Maintenance', 'Safety'] | 26,904,890 | [['E07.325'], ['N02.628'], ['N06.850.135.060.075']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The frequency of Muir-Torre syndrome among Lynch syndrome families. | Lynch syndrome is the predisposition to visceral malignancies that are associated with deleterious germline mutations in DNA mismatch repair genes, including MLH1, MSH2, MSH6, and PMS2. Muir-Torre syndrome is a variant of Lynch syndrome that includes a predisposition to certain skin tumors. We determined the frequency ... | ['Cohort Studies', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'DNA Mismatch Repair', 'Genetic Predisposition to Disease', 'Germ-Line Mutation', 'Humans', 'Incidence', 'MutS Homolog 2 Protein', 'Skin Neoplasms'] | 18,270,343 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C04.588.274.476.411.307.190', 'C04.700.250', 'C06.301.371.411.307.190', 'C06.405.249.411.307.190', 'C06.405.469.158.356.190', 'C06.405.469.491.307.190', 'C16.320.700.250', 'C18.452.284.255'], ['G02.111.222.220', 'G05.219.220'], ['C23.550.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Trend in mode of delivery in Rajavithi Hospital: a ten-year analysis (2002-2011). | OBJECTIVE: To create trends in mode of delivery both public and private service at Rajavithi Hospital.MATERIAL AND METHOD: The medical records of singleton pregnant women delivered between January 1, 2002 and December 31, 2011 were retrospectively analyzed for mode of delivery, indication of operative obstetrics, and m... | ['Adult', 'Delivery, Obstetric', 'Female', 'Humans', 'Obstetrics and Gynecology Department, Hospital', 'Pregnancy', 'Retrospective Studies', 'Thailand', 'Young Adult'] | 24,319,844 | [['M01.060.116'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.495', 'N04.452.442.452.422.495'], ['G08.686.784.769'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Predicting electroporation of cells in an inhomogeneous electric field based on mathematical modeling and experimental CHO-cell permeabilization to propidium iodide determination. | High voltage electric pulses cause electroporation of the cell membrane. Consequently, flow of the molecules across the membrane increases. In our study we investigated possibility to predict the percentage of the electroporated cells in an inhomogeneous electric field on the basis of the experimental results obtained ... | ['Animals', 'CHO Cells', 'Cell Membrane Permeability', 'Cell Proliferation', 'Cricetinae', 'Cricetulus', 'Electricity', 'Electroporation', 'Models, Biological', 'Propidium'] | 24,731,594 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['G03.143.335', 'G04.175'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G01.358.500.249'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['E05.599.395'], ['D03.633.300.633.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NHLBI viewpoint: Lung health and disease prevention research starting in childhood. | Lung health begins in utero when the complex structure of the airway, alveolar, and vascular structures are formed. To really impact the United States and global burden of chronic lung diseases in both adults and children, we must understand normal and abnormal development, the outcomes of disrupted development, and th... | ['Adult', 'Child', 'Chronic Disease', 'Humans', 'Lung', 'Lung Diseases', 'National Heart, Lung, and Blood Institute (U.S.)', 'United States'] | 25,857,257 | [['M01.060.116'], ['M01.060.406'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C08.381'], ['I01.409.418.750.600.650.496.300', 'N03.540.052.750.300', 'N03.540.348.500.500.600.650.496.300'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Clinical application of Web Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo): Patterns of blood sampling and patient characteristics among clinician users. | BACKGROUND: Use of population pharmacokinetics (PopPK) to facilitate PK-informed prophylaxis in clinical practice has gained momentum among haemophilia providers due to the accessibility of tools such as the Web Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) and availability of extended half-life... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Blood Specimen Collection', 'Child', 'Child, Preschool', 'Dose-Response Relationship, Drug', 'Factor VIII', 'Hemophilia A', 'Humans', 'Infant', 'Internet', 'Middle Aged', 'Physicians', 'Young Adult'] | 31,742,831 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['M01.060.406'], ['M01.060.406.448'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['C15.378.100.100.500', 'C15.378.100.141.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Knowledge, Attitudes and Practices of Mothers in Kosova About Complementary Feeding for Infant and Children 6-24 Months. | AIM: This cross sectional study assessed knowledge, attitudes and practices regarding complementary feeding among mothers with children between 6-24 months at the national level.METHODS: The sample of 492 mothers with children between 6-24 months, with a confidence level of 95%, the acceptable margin of 5%, the expecte... | ['Adult', 'Child Development', 'Cross-Sectional Studies', 'Educational Status', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Infant', 'Infant Nutritional Physiological Phenomena', 'Kosovo', 'Male', 'Mothers', 'Nutrition Surveys', 'Prevalence'] | 28,428,672 | [['M01.060.116'], ['F01.525.200', 'G07.345.374.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N01.824.196'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.203.650.220.500'], ['Z01.542.248.506'], ['F01.829.263.500.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
American Association of Gynecologic Laparoscopists 1988 Membership Survey on Operative Hysteroscopy [correction of hysterectomy]. | The 1988 American Association of Gynecologic Laparoscopists' (AAGL) Membership Survey on Operative Hysteroscopy had a 19% response rate. A total of 377 respondents reported performing 7,293 operative hysteroscopies. The number of procedures reported per respondent ranged from 1 to 325; 75% of physicians reported perfor... | ['Female', 'Humans', 'Hysteroscopy', 'Infertility, Female', 'Societies, Medical', 'United States', 'Uterine Diseases', 'Uterine Perforation'] | 2,293,542 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.378.330', 'E01.370.388.250.360', 'E04.502.250.360', 'E04.520.360', 'E04.950.300.539'], ['C13.351.500.365.700'], ['N03.540.828.589'], ['Z01.107.567.875'], ['C13.351.500.852'], ['C13.351.500.852.904.500', 'C26.761.853.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Annexin A6-induced inhibition of cytoplasmic phospholipase A2 is linked to caveolin-1 export from the Golgi. | The molecular mechanisms regulating the exit of caveolin from the Golgi complex are not fully understood. Cholesterol and sphingolipid availability affects Golgi vesiculation events and involves the activity of cytoplasmic phospholipase A(2) (cPLA(2)). We recently demonstrated that high expression levels of annexin A6 ... | ['Animals', 'Annexin A6', 'Arachidonic Acids', 'CHO Cells', 'COS Cells', 'Caveolin 1', 'Chlorocebus aethiops', 'Cholesterol', 'Cricetinae', 'Cricetulus', 'Enzyme Inhibitors', 'Golgi Apparatus', 'HeLa Cells', 'Humans', 'Organophosphonates', 'Phospholipases A2, Cytosolic', 'Protein Transport', 'RNA, Small Interfering', '... | 18,245,088 | [['B01.050'], ['D12.776.157.125.050.110'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['A11.251.210.200', 'A11.436.155'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D12.644.360.024.264', 'D12.776.157.057.010', 'D12.776.476.024.280', 'D12.776.543.990.100.500', 'D12.776.744.287'], ['B01.050.150.900.649.313.988.40... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correction of glucose carbon recycling for the determination of 'true' hepatic glucose production rates by (1-13C1)glucose. | Hepatic glucose production (HGP) and glucose carbon recycling are traditionally estimated by the combined use of hydrogen and carbon-labeled glucose tracers. A single-isotope method such as that of Reichard et al. for the determination of HGP and glucose carbon recycling requires the determination of activities in diff... | ['Adult', 'Aged', 'Carbon Isotopes', 'Colonic Neoplasms', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Glucose', 'Humans', 'Liver', 'Male', 'Middle Aged'] | 2,054,392 | [['M01.060.116'], ['M01.060.116.100'], ['D01.268.150.075', 'D01.496.123'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling. | The emerging concept of generating cancer stem cells from epithelial-mesenchymal transition has attracted great interest; however, the factors and molecular mechanisms that govern this putative tumor-initiating process remain largely elusive. We report here that miR-200a not only regulates epithelial-mesenchymal transi... | ['Animals', 'Blotting, Western', 'Cell Differentiation', 'Enzyme-Linked Immunosorbent Assay', 'Epithelial-Mesenchymal Transition', 'Female', 'Flow Cytometry', 'Homeodomain Proteins', 'Immunoenzyme Techniques', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'MicroRNAs', 'Nasopharyngeal Neoplasms', 'Neoplastic Stem Cells',... | 20,826,811 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.152'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['G04.356.500'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cholecystectomy or not after percutaneous cholecystostomy for acute calculous cholecystitis in high-risk patients. | BACKGROUND/AIMS: This study aims to evaluate the outcomes of percutaneous cholecystostomy for acute calculous cholecystitis in patients with high surgical risk and determine whether subsequent cholecystectomy is beneficial and necessary. Percutaneous cholecystostomy has been shown to be a safe treatment option for pati... | ['Aged', 'Aged, 80 and over', 'Cholecystitis, Acute', 'Cholecystostomy', 'Female', 'Gallstones', 'Humans', 'Male', 'Middle Aged', 'Recurrence'] | 19,102,330 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C06.130.564.263.500'], ['E04.035.195', 'E04.210.120.195'], ['C06.130.409.633', 'C06.130.564.332.500', 'C23.300.175.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.291.937']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pain management practices in paediatric emergency departments in Australia and New Zealand: a clinical and organizational audit by National Health and Medical Research Council's National Institute of Clinical Studies and Paediatric Research in Emergency Departments International Collaborative. | OBJECTIVE: To audit pain management practices and organization in paediatric ED across Australia and New Zealand.METHODS: Retrospective audit of pain management practices in Paediatric Research in Emergency Departments International Collaborative ED in 20 cases each of migraine, abdominal pain and femoral shaft fractur... | ['Abdominal Pain', 'Analgesics', 'Australia', 'Emergency Service, Hospital', 'Femoral Fractures', 'Humans', 'Medical Audit', 'Migraine Disorders', 'New Zealand', 'Pain Management', 'Pain Measurement', 'Patient Education as Topic', 'Pediatrics', 'Practice Guidelines as Topic', "Practice Patterns, Physicians'", 'Retrospe... | 19,527,281 | [['C23.888.592.612.054', 'C23.888.821.030'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['Z01.639.100', 'Z01.678.100.373'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['C26.404.061', 'C26.558.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05.70... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice. | ETHNOPHARMACOLOGICAL RELEVANCE: Flower bud of Tussilago farfara L. is widely used for the treatment of cough, bronchitis and asthmatic disorders in the Traditional Chinese Medicine. However, due to the increasing demands, adulteration with rachis is frequently encountered in the marketplace. No report demonstrated the ... | ['Ammonia', 'Animals', 'Antitussive Agents', 'Chlorogenic Acid', 'Cough', 'Disease Models, Animal', 'Drug Contamination', 'Drugs, Chinese Herbal', 'Expectorants', 'Female', 'Flowers', 'Magnetic Resonance Spectroscopy', 'Male', 'Metabolome', 'Metabolomics', 'Mice', 'Mice, Inbred ICR', 'Multivariate Analysis', 'Phenolsul... | 22,210,102 | [['D01.362.075', 'D01.625.050'], ['B01.050'], ['D27.505.954.427.153', 'D27.505.954.796.090'], ['D02.241.223.200.185', 'D02.241.223.268.220'], ['C08.618.248', 'C23.888.852.293'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['N06.850.360'], ['D20.215.784.500.350', 'D26.335'], ['D27.505.954.796.250'], ['A18.024.249.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Staphylococcus pasteuri sp. nov., isolated from human, animal, and food specimens. | A new novobiocin-susceptible species of the genus Staphylococcus, Staphylococcus pasteuri, is described on the basis of the results of a study of seven strains isolated from human, animal, and food specimens. DNA relatedness experiments (S1 nuclease method) showed that these strains form a homogeneous genomic species r... | ['Amino Acids', 'Animals', 'Bacterial Typing Techniques', 'Cell Wall', 'DNA, Bacterial', 'DNA, Ribosomal', 'Food Microbiology', 'Humans', 'Microbial Sensitivity Tests', 'Novobiocin', 'Phenotype', 'Polymorphism, Restriction Fragment Length', 'Staphylococcus', 'Teichoic Acids'] | 8,098,615 | [['D12.125'], ['B01.050'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['A11.284.183'], ['D13.444.308.212'], ['D13.444.308.475'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Clinical efficacy of lomefloxacin for associated infection in patients with hematological diseases]. | We have studied the clinical effect of lomefloxacin (LFLX) for the documented infections in the patients with hematological disorders, and also analyzed the prophylactic usefulness of LFLX for the prevention of succeeding infection after the chemotherapy. Fifty five patients were entered in the trial, and 51 patients w... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Infective Agents', 'Bacterial Infections', 'Female', 'Fluoroquinolones', 'Hematologic Diseases', 'Humans', 'Male', 'Middle Aged', 'Quinolones', 'Respiratory Tract Infections', 'Urinary Tract Infections'] | 9,077,072 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122'], ['C01.150.252'], ['D03.633.100.810.835.322'], ['C15.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.633.100.810.835'], ['C01.748', 'C08.730'], ['C01.915', 'C12.777.892', 'C13.351.968.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Apical stress distribution on maxillary central incisor during various orthodontic tooth movements by varying cemental and two different periodontal ligament thicknesses: a FEM study. | CONTEXT: During fixed orthodontic therapy, when the stress levels in the periodontal ligament (PDL) exceedsan optimum level, it could lead to root resorption.AIMS: To determine an apical stress incident on the maxillary central incisor during tooth movement with varying cemental and periodontal ligament thickness by Fi... | ['Adolescent', 'Adult', 'Alveolar Process', 'Biomechanical Phenomena', 'Computer Simulation', 'Dental Cementum', 'Dental Enamel', 'Dental Pulp', 'Dentin', 'Finite Element Analysis', 'Humans', 'Imaging, Three-Dimensional', 'Incisor', 'Maxilla', 'Models, Biological', 'Orthodontic Extrusion', 'Periodontal Ligament', 'Rota... | 22,945,712 | [['M01.060.057'], ['M01.060.116'], ['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['G01.154.090', 'G01.374.089'], ['L01.224.160'], ['A14.549.167.646.267', 'A14.549.167.900.250'], ['A14.549.167.900.255'], ['A14.549.167.900.260'], ['A14.549.167.900.280'], ['E05.355'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Pi sampling: a methodical and flexible approach to initial macromolecular crystallization screening. | The Pi sampling method is derived from the incomplete factorial approach to macromolecular crystallization screen design. The resulting `Pi screens' have a modular distribution of a given set of up to 36 stock solutions. Maximally diverse conditions can be produced by taking into account the properties of the chemicals... | ['Algorithms', 'Animals', 'Crystallization', 'Humans', 'Membrane Proteins', 'Receptors, G-Protein-Coupled', 'Solutions'] | 21,543,849 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E05.196.300', 'G02.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['D12.776.543.750.695'], ['D26.776']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Culture and identification of breast cancer stem cells]. | OBJECTIVE: To isolate breast cancer stem cells from breast cancer patients and identify their biological characteristics.METHODS: Mammospheric cells were purified and enriched from the tumor tissues of breast cancer patients using mammosphere culture. Their expressions of CD44 and CD24 were analyzed by flow cytometry, ... | ['Adult', 'Aldehyde Dehydrogenase 1 Family', 'Animals', 'Aryldialkylphosphatase', 'Breast Neoplasms', 'CD24 Antigen', 'Cell Culture Techniques', 'Female', 'Humans', 'Hyaluronan Receptors', 'Isoenzymes', 'Mice', 'Mice, Inbred NOD', 'Mice, SCID', 'Middle Aged', 'Neoplastic Stem Cells', 'Octamer Transcription Factor-3', '... | 22,200,704 | [['M01.060.116'], ['D08.811.682.657.163.249.188'], ['B01.050'], ['D08.811.277.352.660.500'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.395.550.200.098', 'D12.776.395.550.448.120', 'D12.776.543.484.500.120', 'D12.776.543.550.200.124', 'D12.776.543.550.418.120', 'D23.050.285.018', 'D23.050.301.350.098'], ['E01.370.22... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Substrate rigidity-dependent positive feedback regulation between YAP and ROCK2. | Extracellular matrix (ECM) stiffness influences gene expression, leading to modulation of various cellular functions. While ROCK2 regulates actomyosin activity as well as cell migration and proliferation, expression of ROCK2 is increased in response to stiffening ECM. However, the mechanism underlying rigidity-dependen... | ['Actin Cytoskeleton', 'Actomyosin', 'Adaptor Proteins, Signal Transducing', 'Cell Movement', 'Extracellular Matrix', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Phosphoproteins', 'Transcription Factors', 'rho-Associated Kinases'] | 28,686,514 | [['A11.284.430.214.190.750.050'], ['D12.776.210.500.154'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G04.198', 'G07.568.500.180'], ['A11.284.295.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['D12.776.744'], ['D12.776.930'], ['D08.811.913.696.620.682.700.814'... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Urinary excretion and renal clearance of several specific plasma proteins in diabetics]. | The 24-h urine excretion and renal clearance of albumin, alpha I-acid glycoprotein, transferrin, IgG, IgA and haptoglobin were studied in 30 albustix-negative diabetics with no clinical data for diabetic nephropathy aiming at the precise characterization of proteinuria in patients with diabetes mellitus. The diabetic p... | ['Blood Proteins', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Haptoglobins', 'Humans', 'Metabolic Clearance Rate', 'Proteinuria'] | 3,617,708 | [['D12.776.124'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of fear appeals and physiological arousal upon emotion, attitudes, and cigarette smoking. | Two experiments are reported that attempted to replicate conceptually Schachter's theory of the determinants of emotion and to test the feasibility of extending the theory to attitudes and behavior that may be mediated by the emotion of fear. A total of 279 cigarette smokers were administered either epinephrine or a pl... | ['Adult', 'Arousal', 'Attitude', 'Clinical Trials as Topic', 'Emotions', 'Epinephrine', 'Fear', 'Humans', 'Placebos', 'Self-Assessment', 'Smoking Prevention', 'Visual Perception'] | 1,107,512 | [['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['F01.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F01.470'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['F01.470.361'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Peptic ulcer disease with related drug treatment in pregnant women and congenital abnormalities in their offspring. | Peptic ulcer disease (PUD) is a common disease which can also occur in pregnant women. However, the possible association of PUD and related drug treatments in pregnant women with the risk of structural birth defects (i.e. congenital abnormalities [CA]) in their offspring has not been estimated in controlled population-... | ['Abnormalities, Drug-Induced', 'Adolescent', 'Adult', 'Antacids', 'Anti-Ulcer Agents', 'Female', 'Histamine H2 Antagonists', 'Humans', 'Hungary', 'Infant, Newborn', 'Peptic Ulcer', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Proton Pump Inhibitors', 'Registries', 'Sucralfate'] | 20,727,001 | [['C16.131.042'], ['M01.060.057'], ['M01.060.116'], ['D27.505.519.170', 'D27.505.954.483.080'], ['D27.505.954.483.203'], ['D27.505.519.625.375.425.425', 'D27.505.696.577.375.425.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['M01.060.703.520'], ['C06.405.469.275.800', 'C06.405.748.586'], ... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Single-port laparoscopic retroperitoneal surgery: initial operative experience and comparative outcomes. | OBJECTIVES: To present the initial operative outcomes and comparative data among patients undergoing single-port laparoscopic retroperitoneal surgery (SPLRS).METHODS: A prospective, observational study of all patients who underwent SPLRS was performed. The salient demographic and operative data, including age, body mas... | ['Adult', 'Aged', 'Female', 'Humans', 'Kidney Neoplasms', 'Laparoscopy', 'Male', 'Middle Aged', 'Nephrectomy', 'Prospective Studies', 'Retroperitoneal Space', 'Retrospective Studies', 'Treatment Outcome'] | 19,362,331 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['E04.950.774.435'], ['E05.318.372.500.750.625', 'N05.715.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Managing crises through organisational development: a conceptual framework. | This paper presents a synthesis of the guiding principles in crisis management in accordance with the four configurational imperatives (strategy, structure, leadership and environment) defined by Miller (1987) and outlines interventions in organisational development (OD) that may contribute to their achievement. The ai... | ['Community-Institutional Relations', 'Disaster Planning', 'Humans', 'Leadership', 'Organizational Culture', 'Organizational Innovation', 'Organizational Objectives', 'Risk Management'] | 21,083,850 | [['N04.452.822.210'], ['N06.230.100.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['N04.452.606'], ['N04.452.610'], ['N04.452.615'], ['N03.219.463.800', 'N04.452.871']] | ['Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
CSF beta-endorphin levels in patients with infantile autism. | We measured CSF levels of beta-endorphin, an opioid hormone, in 19 patients with infantile autism and in 3 patients with Rett syndrome, and compared them with control values. In infantile autism, CSF levels of beta-endorphin did not differ significantly from those of age-matched controls. There was no significant corre... | ['Autistic Disorder', 'Child', 'Female', 'Humans', 'Male', 'Matched-Pair Analysis', 'Neurons', 'Rett Syndrome', 'Self-Injurious Behavior', 'Stereotyped Behavior', 'beta-Endorphin'] | 9,105,966 | [['F03.625.164.113.500'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.485', 'E05.318.740.475', 'N05.715.360.325.500', 'N05.715.360.750.500', 'N06.850.520.445.485', 'N06.850.520.830.475'], ['A08.675', 'A11.671'], ['C10.597.606.360.455.937', 'C16.320.322.500.937', 'C16.320.400.525.937'... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Simvastatin ameliorates glomerulosclerosis in Adriamycin-induced-nephropathy rats. | The aim of this study was to investigate the effects of simvastatin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, on inflammation and glomerulosclerosis in Adriamycin (ADR)-induced nephropathy. Male Sprague-Dawley rats were randomly divided into control, ADR nephrosis, and simva... | ['Animals', 'Antibiotics, Antineoplastic', 'Disease Models, Animal', 'Doxorubicin', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Interleukin-1beta', 'Kidney', 'Kidney Diseases', 'Male', 'NF-kappa B', 'Rats', 'Rats, Sprague-Dawley', 'Sclerosis', 'Simvastatin', 'Transforming Growth Factor beta1'] | 18,791,746 | [['B01.050'], ['D27.505.954.248.106'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aqueous-phase secondary organic aerosol and organosulfate formation in atmospheric aerosols: a modeling study. | We have examined aqueous-phase secondary organic aerosol (SOA) and organosulfate (OS) formation in atmospheric aerosols using a photochemical box model with coupled gas-phase chemistry and detailed aqueous aerosol chemistry. SOA formation in deliquesced ammonium sulfate aerosol is highest under low-NO(x) conditions, wi... | ['Aerosols', 'Atmosphere', 'Models, Theoretical', 'Organic Chemicals', 'Sulfur'] | 22,788,757 | [['D20.280.055', 'D26.255.165.055'], ['G16.500.275.063', 'N06.230.300.100'], ['E05.599'], ['D02'], ['D01.268.185.900']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
IFN-ã-driven intratumoral microenvironment exhibits superior prognostic effect compared with an IFN-á-driven microenvironment in patients with colon carcinoma. | Interferon (IFN)-á and IFN-ã are cytokines with potent immunomodulating and anti-tumor activities. It is unknown which of the two IFNs may be more potent in the regulation of an anti-tumorigenic response in colorectal carcinoma or whether both cytokines cooperate. We, therefore, established human myxovirus resistance p... | ['Adult', 'Aged', 'Aged, 80 and over', 'Colonic Neoplasms', 'Cytokines', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'GTP-Binding Proteins', 'Humans', 'Interferon-alpha', 'Interferon-gamma', 'Male', 'Middle Aged', 'Myxovirus Resistance Proteins', 'Neoplasm Proteins', 'Retrospective Studies', 'Survival Rate'... | 24,121,019 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Secreted frizzled related protein 1 modulates taxane resistance of human lung adenocarcinoma. | Taxanes, such as docetaxel and taxol, have been used as firstline chemotherapies in advanced lung adenocarcinoma (LAD), but limited responses to chemotherapy remain a major impediment in the clinic. Treatment with 5-azacytidine increases the sensitivity of SPC-A1/DTX cell line to taxanes. The results of DNA methylation... | ['Adenocarcinoma', 'Adenocarcinoma of Lung', 'Animals', 'Antineoplastic Agents', 'Azacitidine', 'Bridged-Ring Compounds', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'DNA Methylation', 'Drug Resistance, Neoplasm', 'Gene Expression Regulation, Neoplastic', 'Gene Knockdown Techniques', 'Humans', 'Intercellular ... | 24,643,460 | [['C04.557.470.200.025'], ['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['B01.050'], ['D27.505.954.248'], ['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['D02.455.426.100', 'D04.075'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.50... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Publication bias in clinical trials and economic analyses. | Publication bias is an established notion in the clinical literature; essentially, large studies or positive results are more likely to find their way into the public domain than small studies or negative results. Meta-analysis presents a focus for the problems of publication bias, seeking to summarise the evidence in ... | ['Clinical Trials as Topic', 'Cost-Benefit Analysis', 'Enalapril', 'Publication Bias'] | 10,169,384 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['N03.219.151.125'], ['D12.644.456.345.360'], ['L01.737.813']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Telomeres and prognosis in patients with chronic lymphocytic leukaemia. | In the present study, telomere length, telomerase activity, the mutation load of immunoglobulin variable heavy chain (IGHV) genes, and established prognostic factors were investigated in 78 patients with chronic lymphocytic leukaemia (CLL) to determine the impact of telomere biology on the pathogenesis of CLL. Telomere... | ['Disease-Free Survival', 'Female', 'Humans', 'Immunoglobulin Heavy Chains', 'Immunoglobulin Variable Region', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Male', 'Mutation', 'Retrospective Studies', 'Survival Rate', 'Telomere'] | 21,203,871 | [['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.705.500', 'D12.776.124.790.651.705.500', 'D12.776.377.715.548.705.500'], ['D12.644.541.500.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells. | Most adenoviruses bind to the coxsackie- and adenovirus receptor (CAR). Surprisingly, CAR is not expressed apically on polarized cells and is thus not easily available to viruses. Consequently, alternative mechanisms for entry of coxsackievirus and adenovirus into cells have been suggested. We have found that tear flui... | ['Adenoviruses, Human', 'Cell Line, Tumor', 'Coxsackie and Adenovirus Receptor-Like Membrane Protein', 'Epithelial Cells', 'Humans', 'Lactoferrin', 'Receptors, Virus', 'Species Specificity', 'Tears'] | 17,079,302 | [['B04.280.030.500.350'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.395.550.200.537.500', 'D12.776.543.550.200.537.500', 'D12.776.543.750.830.124', 'D12.776.543.940.600.500', 'D23.050.301.350.537.500'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.471', 'D08.811.277.65... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of APOE epsilon4 allele on cerebral glucose metabolism in AD is a function of age at onset. | BACKGROUND: Although the APOE epsilon4 allele is a well-known risk factor for developing AD, the impact of the epsilon4 allele on clinical manifestations in patients with AD is still controversial. One possible reason for this controversy is that previous studies did not consider the effect of patient age at symptom on... | ['Age of Onset', 'Aged', 'Aging', 'Alleles', 'Alzheimer Disease', 'Apolipoprotein E4', 'Apolipoproteins E', 'Cerebral Cortex', 'Female', 'Genotype', 'Glucose', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies'] | 11,889,238 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['G07.345.124'], ['G05.360.340.024.340.030'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D10.532.091.500.750', 'D12.776.070.400.500.750', 'D12.776.521.120.500.750'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.50... | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Parental characteristics of Jews and Greeks in Australia. | A controlled study was conducted in Sydney to assess the reported characteristics of Jewish and Greek parents. Using a measure of fundamental parental characteristics the 81 Jewish subjects differed from controls only in scoring their mothers as less caring. The 125 Greek subjects scored both parents as more overprotec... | ['Adult', 'Australia', 'Child', 'Child Rearing', 'Ethnic Groups', 'Female', 'Greece', 'Humans', 'Jews', 'Male', 'Parent-Child Relations', 'Parents'] | 293,176 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analogical encoding facilitates knowledge transfer in negotiation. | Information learned in one situation often fails to transfer to a similarly structured situation. However, prior findings suggest that comparing two or more instances that embody the same principle can promote abstraction of a schema that can be transferred to new situations. In two lines of research, we examined the e... | ['Adult', 'Decision Making', 'Decision Making, Organizational', 'Female', 'Humans', 'Knowledge of Results, Psychological', 'Male', 'Negotiating', 'Problem Solving', 'Transfer, Psychology'] | 10,682,201 | [['M01.060.116'], ['F02.463.785.373'], ['N04.452.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.770.379'], ['F01.145.209.520', 'F01.829.401.520', 'F02.463.785.373.520', 'L01.143.620', 'N04.452.677.430'], ['F02.463.425.725', 'F02.463.785.810'], ['F02.463.425.910']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Chromatographic analysis of serotonin, 5-hydroxyindolacetic acid and homovanillic acid in dried blood spots and platelet poor and rich plasma samples. | An isocratic high-performance liquid chromatographic method has been developed for the measurement of serotonin, 5-hydroxyindolacetic and homovanillic acids in dried blood spots and in platelet poor and rich plasma samples. Analyses were carried out on a C18 reversed-phase column using a mobile phase composed of 13% me... | ['Chromatography, High Pressure Liquid', 'Homovanillic Acid', 'Humans', 'Indoles', 'Plasma', 'Serotonin'] | 20,554,289 | [['E05.196.181.400.300'], ['D02.241.223.601.521'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.050.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavior changes after notification of HIV infection. | BACKGROUND: To learn more about how people who did not volunteer for testing react to information about HIV infection, we assessed short-term behavior changes in HIV-positive blood donors.METHODS: Blood donors who were notified at the New York Blood Center that they were HIV positive were asked to participate in a stud... | ['Adolescent', 'Adult', 'Blood Donors', 'Female', 'Follow-Up Studies', 'HIV Seropositivity', 'Humans', 'Logistic Models', 'Male', 'Mass Screening', 'Middle Aged', 'New York City', 'Risk Factors', 'Sexual Behavior', 'Substance Abuse, Intravenous', 'Surveys and Questionnaires'] | 1,746,654 | [['M01.060.057'], ['M01.060.116'], ['M01.898.313'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500', 'C20.673.480.500'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A-myb rescues murine B-cell lymphomas from IgM-receptor-mediated apoptosis through c-myc transcriptional regulation. | A-myb is a member of the myb family of transcription factors, which regulates proliferation, differentiation, and apoptosis of hematopoietic cells. A-Myb expression is normally restricted to the proliferating B-cell centroblasts and transgenic mice overexpressing A-myb displayed enhanced hyperplasia of the lymph nodes.... | ['Animals', 'Apoptosis', 'Gene Expression Regulation, Neoplastic', 'Genes, myb', 'Genes, myc', 'Humans', 'Lymphoma, B-Cell', 'Mice', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-myb', 'Receptors, Fc', 'Trans-Activators', 'Transcription, Genetic'] | 10,910,917 | [['B01.050'], ['G04.146.954.035'], ['G05.308.370'], ['G05.360.340.024.340.375.500.791.418'], ['G05.360.340.024.340.375.500.791.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480.150', 'C15.604.515.569.480.150', 'C20.683.515.761.480.150'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.624... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of iso-á-acids, the hop-derived bitter components in beer, on the MRI-based Brain Healthcare Quotient in healthy middle-aged to older adults. | AIM: Neurological disorders are a major public health issue worldwide and are often associated with structural changes in the brain. We have previously demonstrated that iso-á-acids (IAAs), the hop-derived bitter components in beer, improve memory impairment in aged and Alzheimer's disease mouse models. In this study, ... | ['Acids', 'Aged', 'Beer', 'Brain', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Organ Size'] | 31,587,526 | [['D01.029'], ['M01.060.116.100'], ['G07.203.100.100.200', 'G07.203.200.250', 'J02.200.100.200', 'J02.350.250'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Including irrigation in niche modelling of the invasive wasp Vespula germanica (Fabricius) improves model fit to predict potential for further spread. | The European wasp, Vespula germanica (Fabricius) (Hymenoptera: Vespidae), is of Palaearctic origin, being native to Europe, northern Africa and Asia, and introduced into North America, Chile, Argentina, Iceland, Ascension Island, South Africa, Australia and New Zealand. Due to its polyphagous nature and scavenging beha... | ['Agricultural Irrigation', 'Animal Distribution', 'Animals', 'Argentina', 'Australia', 'Introduced Species', 'Models, Theoretical', 'Seasons', 'South Africa', 'Stress, Physiological', 'Temperature', 'Wasps', 'Water'] | 28,715,452 | [['J01.040.044'], ['F01.145.113.069', 'G16.049'], ['B01.050'], ['Z01.107.757.077'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['E05.599'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['Z01.058.290.175.735'], ['G07.775'], ['G01.9... | ['Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Culture-expanded allogenic adipose tissue-derived stem cells attenuate cartilage degeneration in an experimental rat osteoarthritis model. | Mesenchymal stem cell (MSC)-based cell therapy is a promising avenue for osteoarthritis (OA) treatment. In the present study, we evaluated the efficacy of intra-articular injections of culture-expanded allogenic adipose tissue-derived stem cells (ADSCs) for the treatment of anterior cruciate ligament transection (ACLT)... | ['Adipose Tissue', 'Animals', 'Cartilage, Articular', 'Cell Differentiation', 'Cells, Cultured', 'Chondrocytes', 'Coculture Techniques', 'Injections, Intra-Articular', 'Interleukin-1beta', 'Interleukin-6', 'Male', 'Osteoarthritis', 'Rats', 'Rats, Wistar', 'Stem Cell Transplantation', 'Stem Cells', 'Tumor Necrosis Facto... | 28,419,155 | [['A10.165.114'], ['B01.050'], ['A02.165.407.150', 'A02.835.583.192'], ['G04.152'], ['A11.251'], ['A11.329.171'], ['E05.481.500.374'], ['E02.319.267.530.380'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.374.500.400.600', 'D23.529.374.465.131.600', 'D23.529... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of restricted food intake on estrous cycles and pseudopregnancies in dogs. | OBJECTIVE: To examine effects of restricted food intake on estrous cycle frequency, interestrus interval, and pseudopregnancy prevalence in dogs.ANIMALS: 28 female Labrador Retrievers.PROCEDURE: Dogs were paired by body weight when they were 6 weeks old and fed so that the limit-fed pair-mate received 75% of the amount... | ['Age Factors', 'Animal Feed', 'Animals', 'Area Under Curve', 'Dogs', 'Eating', 'Estradiol', 'Estrus', 'Female', 'Male', 'Prevalence', 'Progesterone', 'Prolactin', 'Pseudopregnancy', 'Radioimmunoassay', 'Random Allocation', 'Regression Analysis'] | 10,407,473 | [['N05.715.350.075', 'N06.850.490.250'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.203.650.283', 'G10.261.330'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.6... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Prognostic utility of serum potassium in chronic digoxin toxicity: a case-control study. | OBJECTIVE: In contrast to patients with acute digoxin overdose, the prognostic utility of the serum potassium concentration for patients with chronic digoxin toxicity is unclear. In such patients, we aimed to evaluate the relationship between pre-treatment serum potassium and survival.METHODS: This was a case-control s... | ['Aged', 'Aged, 80 and over', 'Bradycardia', 'Cardiotonic Agents', 'Case-Control Studies', 'Digoxin', 'Female', 'Humans', 'Hyperkalemia', 'Immunoglobulin Fab Fragments', 'Male', 'Potassium', 'Prognosis', 'Prospective Studies', 'Retrospective Studies', 'Sensitivity and Specificity', 'Urban Health Services'] | 21,619,380 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067.319', 'C23.550.073.300'], ['D27.505.954.411.222', 'D27.720.799.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688', 'D09.408.180.261.436'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Present status and perspective of percutaneous transluminal coronary angioplasty from the viewpoint of short and long term results: comparative study of the results of PTCA and CABG procedure. | Balloon technology has advanced to incorporate the skills of angioplasters while efforts to enhance their skills continue. These factors have contributed to the expansion of percutaneous transluminal coronary angioplasty (PTCA) indications. We have analyzed the comparison of short and long term results between PTCA and... | ['Adult', 'Aged', 'Angina, Unstable', 'Angioplasty, Balloon', 'Arteriosclerosis', 'Coronary Artery Bypass', 'Evaluation Studies as Topic', 'Exercise Test', 'Female', 'Follow-Up Studies', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Vascular Patency'] | 2,961,898 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.137.126'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E05.337', 'N05.715... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Equine digital veins are more sensitive to superoxide anions than digital arteries. | This work was designed to investigate (i) the effect of superoxide dismutase (SOD) inhibition on endothelial function and (ii) the free radical-induced endothelial dysfunction in equine digital veins (EDVs) and equine digital arteries (EDAs) isolated from healthy horses. EDV and EDA rings were suspended in a 5 ml organ... | ['Acetylcholine', 'Animals', 'Arteries', 'Ditiocarb', 'Forelimb', 'Horses', 'In Vitro Techniques', 'Phenylephrine', 'Superoxides', 'Vasoconstrictor Agents', 'Vasodilation', 'Vasodilator Agents', 'Veins'] | 25,014,758 | [['D02.092.211.111'], ['B01.050'], ['A07.015.114'], ['D02.241.081.251.869.220', 'D02.886.706.200'], ['A13.395'], ['B01.050.150.900.649.313.984.235.472'], ['E05.481'], ['D02.033.100.291.617', 'D02.092.063.291.617'], ['D01.248.497.158.685.750.850', 'D01.339.431.374.850', 'D01.650.550.750.800', 'D02.389.338.732'], ['D27.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tissue-dissolving capacity and antibacterial effect of buffered and unbuffered hypochlorite solutions. | OBJECTIVE: The goal of this study was to compare the dissolving potential of Dakin's solution with that of equivalent buffered and unbuffered sodium hypochlorite solutions on fresh and decayed tissues. In addition, the antimicrobial effect of Dakin's solution and equivalent unbuffered hypochlorite was tested.STUDY DESI... | ['Analysis of Variance', 'Animals', 'Anti-Infective Agents, Local', 'Buffers', 'Drug Combinations', 'Enterococcus faecalis', 'Mouth Mucosa', 'Root Canal Irrigants', 'Sodium Bicarbonate', 'Sodium Hypochlorite', 'Swine'] | 12,464,903 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.954.122.187'], ['D27.720.470.280'], ['D26.310'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['A10.615.550.599', 'A14.549.512'], ['D25.800', 'D27.505.954.122.425.300.500', 'D27.720.274.300.500', 'J01.637.051.800'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Family therapy with unmarried African American mothers and their adolescents. | Almost two-thirds of African American births are to unmarried mothers, and these single parents are among the most economically vulnerable in the United States. The effects of chronic stressors such as poverty can compromise the ability of these mothers to parent effectively, particularly during the developmental perio... | ['Adolescent', 'African Americans', 'Family Therapy', 'Humans', 'Mother-Child Relations', 'Parent-Child Relations', 'Parenting', 'Single Parent', 'Stress, Psychological', 'United States'] | 11,802,488 | [['M01.060.057'], ['M01.686.508.100.100', 'M01.686.754.100'], ['F04.754.864.581.273'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290.170'], ['F01.829.263.370.290'], ['F01.829.263.370.310'], ['F01.829.263.315.500.725.700', 'F01.829.263.500.320.785', 'I01.240.361.500.725.700', 'I01.880.853.150.42... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Short communication: effect of temporary glycosuria on molasses consumption in Holstein calves. | This study was conducted to determine the effect of experimentally increased glucose demand on voluntary consumption of molasses by dairy calves. Three-week-old calves received 0.365 g of phlorizin by s.c. injection. Urinary output and molasses consumption were measured hourly, and urinary glucose concentration was scr... | ['Animals', 'Cattle', 'Cattle Diseases', 'Eating', 'Glycosuria', 'Male', 'Molasses', 'Phlorhizin', 'Sodium Chloride', 'Time Factors'] | 18,765,619 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['G07.203.650.283', 'G10.261.330'], ['C12.777.934.363', 'C13.351.968.934.363', 'C18.452.394.937'], ['G07.203.300.662', 'J02.500.662'], ['D09.408.702'], ['D01.210.450.150.875', 'D01.857.650'], ['G01.910.857']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Chronic administration of aluminium L-glutamate in young mature rats: effects on iron levels and lipid peroxidation in selected brain areas. | Clinical and experimental studies have demonstrated the neurotoxicity of aluminium (Al), notably as a result of lipid peroxidation in vitro. We previously showed that Al is able to cross the blood-brain barrier as an L-glutamate complex and be deposited in rat brain. The present work in young mature rats investigated t... | ['Aluminum', 'Animals', 'Brain Chemistry', 'Cerebral Cortex', 'Fatty Acids, Unsaturated', 'Glutamates', 'Hippocampus', 'Iron', 'Lipid Peroxidation', 'Male', 'Neostriatum', 'Rats', 'Rats, Wistar', 'Thiobarbituric Acid Reactive Substances'] | 10,048,751 | [['D01.268.557.050', 'D01.552.547.050'], ['B01.050'], ['G02.111.150', 'G03.185'], ['A08.186.211.200.885.287.500'], ['D10.251.355'], ['D12.125.067.625', 'D12.125.119.409'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G02.111.515', 'G03.295.531.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ERP evidence for conflict in contingency learning. | The proportion congruency effect refers to the observation that the magnitude of the Stroop effect increases as the proportion of congruent trials in a block increases. Contemporary work shows that proportion effects can be driven by both context and individual items, and are referred to as context-specific proportion ... | ['Cerebral Cortex', 'Conflict, Psychological', 'Electroencephalography', 'Evoked Potentials', 'Humans', 'Learning', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Reaction Time'] | 28,349,582 | [['A08.186.211.200.885.287.500'], ['F01.658.209'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669... | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of endorphin derivatives on the EEG alterations induced by corticotropin releasing factor in the rabbit hippocampus. | Corticotropin releasing factor (CRF), injected into the cerebral ventricles (i.c.v.) of rabbits, induced EEG limbic seizures, behavioural excitability, stereotyped behaviour and the tardive enhancement of hippocampal theta voltage and frequency. The beta-endorphin cleavage derivatives des-tyr-gamma-endorphin (DT gamma ... | ['Animals', 'Anticonvulsants', 'Corticotropin-Releasing Hormone', 'Electroencephalography', 'Endorphins', 'Hippocampus', 'Male', 'Peptide Fragments', 'Rabbits'] | 2,277,803 | [['B01.050'], ['D27.505.954.427.080'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['E01.370.376.300', 'E01.370.405.245'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D12.644.541']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain responses strongly correlate with Weibull image statistics when processing natural images. | The visual appearance of natural scenes is governed by a surprisingly simple hidden structure. The distributions of contrast values in natural images generally follow a Weibull distribution, with beta and gamma as free parameters. Beta and gamma seem to structure the space of natural images in an ecologically meaningfu... | ['Biostatistics', 'Contrast Sensitivity', 'Electroencephalography', 'Evoked Potentials, Visual', 'Humans', 'Models, Neurological', 'Neurons', 'Pattern Recognition, Visual', 'Visual Perception'] | 19,757,938 | [['E05.318.740.237'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['A08.67... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[PHI+], a novel Sup35-prion variant propagated with non-Gln/Asn oligopeptide repeats in the absence of the chaperone protein Hsp104. | BACKGROUND: The [PSI+] element of the budding yeast is an aggregated form of the translation release factor Sup35 that is propagated and transmitted cytoplasmically in a manner analogous to that of mammalian prions. The N-terminal of Sup35, necessary for [PSI+], contains oligopeptide repeats and multiple Gln/Asn residu... | ['Amino Acid Sequence', 'Asparagine', 'Base Sequence', 'DNA Primers', 'Glycine', 'Heat-Shock Proteins', 'Molecular Sequence Data', 'Peptide Termination Factors', 'Prions', 'Repetitive Sequences, Amino Acid', 'Saccharomyces cerevisiae Proteins'] | 12,839,621 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D12.125.481'], ['D12.776.580.216'], ['L01.453.245.667'], ['D12.776.835.862'], ['D12.776.785'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Tumor-specific hypermethylation of epigenetic biomarkers, including SFRP1, predicts for poorer survival in patients from the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project. | The recent publication of the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project has provided an immense wealth and breadth of data providing an invaluable tool for confirmation and expansion upon previous observations in a large data set containing multiple data types including DNA methylation, somatic mutation, an... | ['Biomarkers, Tumor', 'Carcinoma, Renal Cell', 'Cohort Studies', 'CpG Islands', 'DNA Methylation', 'Epigenesis, Genetic', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Kaplan-Meier Estimate', 'Kidney Neoplasms', 'Membrane Proteins', 'Proportional Hazards Models'] | 24,454,902 | [['D23.101.140'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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