Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Modified Balloon Protection Technique for Preoperative Embolization of Feeder Arteries from Internal Carotid Artery Branches to Skull-Base Tumor: Technical Note. | OBJECTIVE: To improve bleeding management during brain tumor surgery, feeder arteries supplying the tumor are often embolized presurgically. However, access to feeder arteries can be limited, and embolization of feeders from internal carotid artery (ICA) branches often causes complications. We evaluated the PercuSurge ... | ['Adult', 'Balloon Occlusion', 'Blood Loss, Surgical', 'Carotid Artery, Internal', 'Embolization, Therapeutic', 'Female', 'Hemangiopericytoma', 'Humans', 'Male', 'Meningioma', 'Middle Aged', 'Preoperative Care', 'Skull Base Neoplasms'] | 26,356,540 | [['M01.060.116'], ['E02.148.106', 'E02.520.392.500', 'E02.926.500.074', 'E05.157.063'], ['C23.550.414.300', 'C23.550.505.300'], ['A07.015.114.186.200.230'], ['E02.520.360', 'E02.926.500'], ['C04.557.645.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.580.520', 'C04.557.645.520', 'C04.588.614.250.580.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pathologic grade and tumor size are associated with recurrence-free survival in patients with duodenal neuroendocrine tumors. | BACKGROUND: Duodenal neuroendocrine tumors are rare and few studies exist to guide surgical management. This study identifies factors associated with recurrence after resection.METHODS: A retrospective, single institution review was performed between 1983 and 2011 on patients with a pathologic diagnosis of duodenal neu... | ['Adult', 'Aged', 'Aged, 80 and over', 'Ampulla of Vater', 'Common Bile Duct Neoplasms', 'Disease-Free Survival', 'Duodenal Neoplasms', 'Duodenoscopy', 'Duodenum', 'Female', 'Humans', 'Intestinal Mucosa', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Recurrence, Local', 'Neuroendocrine Tu... | 24,448,999 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['C04.588.274.120.250.250', 'C06.130.120.120.280', 'C06.130.120.250.280', 'C06.130.320.120.280', 'C06.301.120.250.250'], ['E01.789.800.190', 'E05.318.740.998.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thinking about thinking: implications for patient safety. | Clinical medicine, a learned, rational, science-using practice, is labelled a science even though physicians have the good sense not to practise it that way. Rather than thinking like scientists - or how we think scientists think - physicians are engaged in analogical, interpretive reasoning that resembles Aristotle's ... | ['Humans', 'Medical Errors', 'Safety Management', 'Thinking'] | 19,667,768 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.450'], ['N04.452.871.900', 'N06.850.135.060.075.800'], ['F02.463.785']] | ['Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro fertilization and risk of childhood leukemia in Greece and Sweden. | BACKGROUND: Cancer risk in children born after in vitro fertilization (IVF) remains largely unknown. We aimed to investigate risk of leukemia and lymphoma following IVF using two nationwide datasets.METHODS: The hospital-based case-control study in Greece derived from the National Registry for Childhood Hematological M... | ['Case-Control Studies', 'Child', 'Child, Preschool', 'Female', 'Fertilization in Vitro', 'Greece', 'Humans', 'Infant', 'Infant, Newborn', 'Leukemia', 'Lymphoma', 'Male', 'Risk Factors', 'Sweden'] | 21,618,418 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['E02.875.800.750', 'E05.820.800.750'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C04.557.337'], ['C04.557.386', 'C15.604.515.569', 'C20.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Biomechanical changes at the knee after lower limb fatigue in healthy young women. | BACKGROUND: The purpose of this study was to identify changes in knee kinematics, kinetics and stiffness that occur during gait due to lower limb neuromuscular fatigue.METHODS: Kinematic, kinetic and electromyographic measures of gait were collected on healthy, young women (n=20) before and after two bouts of fatigue. ... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Biomechanical Phenomena', 'Elasticity', 'Electromyography', 'Female', 'Gait', 'Humans', 'Isometric Contraction', 'Kinetics', 'Knee', 'Muscle Fatigue', 'Muscle, Skeletal', 'Quadriceps Muscle', 'Range of Motion, Articular', 'Reference Values', 'Torque', 'Walking', 'Young A... | 23,528,628 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G01.154.090', 'G01.374.089'], ['G01.374.590'], ['E01.370.405.255', 'E01.370.530.255'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['G01.374.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Chronic bacterial prostatitis as a manifestation of secondary immunodeficiency state]. | The clinico-immunological examination of 57 patients with chronic bacterial prostatitis was carried out. The clinical analysis made it possible to divide the patients into 3 groups characterized by the presence of chronic inflammatory diseases of other organs which had appeared before (group 1) or after (group 2) the m... | ['Adult', 'B-Lymphocytes', 'Bacterial Infections', 'Chronic Disease', 'Humans', 'Immune Tolerance', 'Immunoglobulin A', 'Leukocyte Count', 'Male', 'Middle Aged', 'Prostatitis'] | 9,700,882 | [['M01.060.116'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C01.150.252'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.535.425'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.7... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of low-dose ketanserin on blood pressure variability, baroreflex sensitivity and end-organ damage in spontaneously hypertensive rats. | The present study was designed to investigate the effects of low-dose ketanserin on BPV (blood pressure variability), BRS (baroreflex sensitivity) and organ damage in SHR (spontaneously hypertensive rats). Ketanserin was mixed in rat chow at an estimated dose of 0.1 mg.kg(-1) of body weight.day(-1). SHR were treated fo... | ['Animals', 'Aorta', 'Baroreflex', 'Blood Pressure', 'Diastole', 'Heart', 'Hypertrophy', 'Ketanserin', 'Kidney', 'Male', 'Rats', 'Rats, Inbred SHR', 'Serotonin Antagonists'] | 15,707,387 | [['B01.050'], ['A07.015.114.056'], ['G09.330.380.057', 'G11.561.731.063'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['A07.541'], ['C23.300.775'], ['D03.383.621.365', 'D03.633.100.786.830.333'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental and occupational exposure to bisphenol A and endometriosis: urinary and peritoneal fluid concentration levels. | OBJECTIVES: The study aimed to give a first data set of bisphenol A (BPA) levels in the peritoneal fluid of patients suffering from endometriosis and to investigate the relationship between BPA exposure and endometriosis.METHODS: A questionnaire investigating the occupational context, life environment, and habits was a... | ['Adult', 'Ascitic Fluid', 'Benzhydryl Compounds', 'Biomarkers', 'Case-Control Studies', 'Endometriosis', 'Environmental Exposure', 'Female', 'Humans', 'Occupational Diseases', 'Occupational Exposure', 'Phenols', 'Risk Factors'] | 27,718,009 | [['M01.060.116'], ['A12.207.119'], ['D02.455.426.559.389.115'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C13.351.500.163'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C24'], ['N06.850.460.350.600'], ['D02.455.426.559.389.657'], ['E05.318.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A seven-day Helicobacter pylori treatment regimen using clarithromycin, omeprazole and tripotassium dicitrato bismuthate. | AIM: To evaluate clarithromycin 500 mg t.d.s., tripotassium dicitrato bismuthate 240 mg b.d. and omeprazole 20 mg b.d. for 7 days as a Helicobacter pylori treatment regimen.METHODS: The H. pylori status of dyspeptic patients undergoing endoscopy was assessed by histology, culture and rapid urease testing of biopsies an... | ['Adult', 'Aged', 'Anti-Bacterial Agents', 'Anti-Ulcer Agents', 'Breath Tests', 'Clarithromycin', 'Drug Therapy, Combination', 'Duodenal Ulcer', 'Dyspepsia', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Middle Aged', 'Omeprazole', 'Organometallic Compounds', 'Patient Compliance', 'Urea... | 8,791,951 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['D27.505.954.483.203'], ['E01.370.100'], ['D02.540.576.500.992.100'], ['E02.319.310'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['C23.888.821.236'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Myotubes derived from human-induced pluripotent stem cells mirror in vivo insulin resistance. | Induced pluripotent stem cells (iPS cells) represent a unique tool for the study of the pathophysiology of human disease, because these cells can be differentiated into multiple cell types in vitro and used to generate patient- and tissue-specific disease models. Given the critical role for skeletal muscle insulin resi... | ['Cell Differentiation', 'Child, Preschool', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Infant', 'Insulin', 'Insulin Resistance', 'Muscle Fibers, Skeletal', 'Pluripotent Stem Cells', 'Signal Transduction'] | 26,831,110 | [['G04.152'], ['M01.060.406.448'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['A10.690.552.500.500', 'A11.620.249'], ['A11.872.700'], ['G02.111.... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Efficient on-chip isolation of HIV subtypes. | HIV has caused a global pandemic over the last three decades. There is an unmet need to develop point-of-care (POC) viral load diagnostics to initiate and monitor antiretroviral treatment in resource-constrained settings. Particularly, geographical distribution of HIV subtypes poses significant challenges for POC immun... | ['Antibodies, Immobilized', 'HIV', 'HIV Envelope Protein gp120', 'HIV Infections', 'Humans', 'Microfluidic Analytical Techniques', 'Real-Time Polymerase Chain Reaction', 'Reproducibility of Results', 'Surface Properties', 'Viral Load'] | 22,391,989 | [['D12.776.124.486.485.114.207', 'D12.776.124.790.651.114.207', 'D12.776.377.715.548.114.207', 'D12.776.463.250'], ['B04.820.650.589.650.350'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.776.964.970.880.325.164.249', 'D23.050.327.520.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.64... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An immunohistochemical evaluation of androgen and progesterone receptors in ovarian tumors. | To visualize the heterogeneity of androgen receptor (AR) and progesterone receptor (PR) expression in ovarian tumors, 61 specimens were studied immunohistochemically using specific mouse monoclonal antibodies. The tested ovarian tumors included ovarian carcinomas of serous, mucinous, endometrioid, undifferentiated, and... | ['Carcinoma', 'Cystadenoma', 'Female', 'Granulosa Cell Tumor', 'Humans', 'Immunoenzyme Techniques', 'Ovarian Neoplasms', 'Receptors, Androgen', 'Receptors, Progesterone'] | 8,418,017 | [['C04.557.470.200'], ['C04.557.470.035.320', 'C04.557.470.590.485'], ['C04.557.475.750.656', 'C04.588.322.455.398', 'C13.351.500.056.630.705.398', 'C13.351.937.418.685.398', 'C19.344.410.398', 'C19.391.630.705.398'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.3... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Taxonomic status of <i>Parotia</i> <i>berlepschi</i> Kleinschmidt, 1897 based on analysis of external appearance, voice and behavior (Aves: Paradisaeidae). | Described from trade-skins of unknown origins, Parotia berlepschi Kleinschmidt, 1897 was the subject of a longstanding ornithological mystery that remained unresolved for well over a century. With few specimens and no known wild population, most taxonomic assessments over the last century have treated P. berlepschi as ... | ['Animals', 'Birds', 'Passeriformes', 'Phenotype'] | 29,242,456 | [['B01.050'], ['B01.050.150.900.248'], ['B01.050.150.900.248.620'], ['G05.695']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
c-erbB-2 is not a major factor in the development of colorectal cancer. | We have investigated c-erbB-2 protein expression in a large cohort of well-characterized colorectal tumours, and in a subset of lymph node metastases. We have also evaluated a Val(655)Ile single nucleotide polymorphism, which is associated with an increased risk of breast cancer, in a subset of the colorectal cancer pa... | ['Adenocarcinoma', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Colorectal Neoplasms', 'DNA Primers', 'DNA, Neoplasm', 'Female', 'Genes, erbB-2', 'Humans', 'Immunoenzyme Techniques', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fr... | 11,870,539 | [['C04.557.470.200.025'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.86... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Local area cartilage segmentation: a semiautomated novel method of measuring cartilage loss in knee osteoarthritis. | OBJECTIVE: To assess the responsiveness and reader time of a novel semiautomated tool to detect knee cartilage loss over 2 years in subjects with knee osteoarthritis.METHODS: A total of 122 subjects from the Osteoarthritis Initiative progression cohort were selected. A reader used the software method to segment cartila... | ['Aged', 'Automation', 'Cartilage', 'Disease Progression', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Knee Joint', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Predictive Value of Tests', 'Severity of Illness Index', 'Software', 'Time Factors'] | 24,664,976 | [['M01.060.116.100'], ['J01.897.104'], ['A02.165', 'A10.165.382'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['A02.835.583.475'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E05... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
[Therapeutic bronchoscopic treatment of postintubation tracheal stenosis: 5 cases]. | Benign airway obstruction is known as curable by therapeutic bronchoscopic methods. Compared by surgical therapies it is comfortable and has no risks for the patients. For five patients who applied our clinic after tracheostomy and endotracheal intubation stenosis we used therapeutic bronchoscopic methods; "laser-steno... | ['Adult', 'Aged', 'Bronchoscopy', 'Catheterization', 'Diagnosis, Differential', 'Female', 'Humans', 'Intubation, Intratracheal', 'Laser Coagulation', 'Male', 'Middle Aged', 'Tracheal Stenosis'] | 15,558,359 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['E02.148', 'E05.157'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E02.520.745.410', 'E02.594.530', 'E04.014.520.530', 'E04.350.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The impact of uncertainty in a blood coagulation model. | Deterministic mathematical models of biochemical processes operate as if the empirically derived rate constants governing the dynamics are known with certainty. Our objective in this study was to explore the sensitivity of a deterministic model of blood coagulation to variations in the values of its 44 rate constants. ... | ['Algorithms', 'Analysis of Variance', 'Animals', 'Blood Coagulation', 'Blood Coagulation Factors', 'Computer Simulation', 'Factor VIIa', 'Humans', 'Kinetics', 'Models, Biological', 'Thrombin', 'Thromboplastin', 'Uncertainty'] | 19,451,209 | [['G17.035', 'L01.224.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G09.188.390.150'], ['D12.776.124.125', 'D23.119'], ['L01.224.160'], ['D08.811.277.656.300.760.300', 'D08.811.277.656.959.350.300', 'D12.776.124.125.325.300', 'D23.119.325.300'], ['B01.050.150.900.649.313.988.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Use of citation indexes and impact factors]. | Article deals with evaluation method of scientific works by means of Citation Indexes and Impact Factor which are produced by Institute for Scientific Information of Philadelphia. It criticize criteria of the usage of Impact factor and way of research workers evaluation. | ['Abstracting and Indexing', 'Bibliometrics', 'Publishing', 'Research'] | 10,566,222 | [['L01.453.245.100'], ['L01.178.682.099.325', 'L01.453.183.291'], ['L01.737'], ['H01.770.644']] | ['Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Changes in glucose tolerance during three years' follow-up in an elderly population. | The aim of this study was to describe changes in glucose tolerance over 3 y and to establish the prevalence of diabetes and impaired glucose tolerance in an unselected non-institutionalised elderly population aged 70 y or over at the beginning of the study. Diabetes was assessed on the basis of self-reports and 2 h ora... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Diabetes Mellitus', 'Female', 'Finland', 'Follow-Up Studies', 'Glucose Tolerance Test', 'Humans', 'Male', 'Prevalence', 'Sex Factors'] | 10,483,080 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C18.452.394.750', 'C19.246'], ['Z01.542.816.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Sr2+ and quantal events at excitatory synapses between mouse hippocampal neurons in culture. | 1. Whole-cell recording from pairs of adjacent mouse hippocampal neurons in culture was used to study the quantal properties of action potential-evoked excitatory synaptic transmission and to demonstrate the use of Sr2+ in quantifying those properties. 2. In the presence of extracellular Sr2+, excitatory postsynaptic c... | ['Animals', 'Culture Techniques', 'Hippocampus', 'Mice', 'Mice, Inbred Strains', 'Patch-Clamp Techniques', 'Strontium', 'Synaptic Transmission'] | 8,866,356 | [['B01.050'], ['E05.481.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['E05.200.500.905', 'E05.242.800'], ['D01.268.552.850', 'D01.268.556.825', 'D01.552.539.861', 'D01.552.544.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Risk factors of thickened intima-media and atherosclerotic plaque development in carotid arteries in patients with systemic lupus erythematosus]. | INTRODUCTION: The aim of the study was: (1) The evaluation of the frequency of intima-media thickening (IMT) and the presence of atherosclerotic plaques in carotid arteries in patients with systemic lupus erythematosus (SLE) in comparison with the control group. (2) The evaluation of the correlation between IMT and the... | ['Adult', 'Age Distribution', 'Age Factors', 'Aged', 'Carotid Arteries', 'Carotid Artery Diseases', 'Case-Control Studies', 'Comorbidity', 'Female', 'Humans', 'Incidence', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Risk Factors', 'Sex Distribution', 'Sex Factors', 'Tunica Intima', 'Tunica Media', 'Ultraso... | 19,374,227 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['A07.015.114.186'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N05.715.350.225', 'N06.850.490.687'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Synthesis and cytotoxicity of allobetulin derivatives]. | The synthesis and screening of antitumor activity in vitro (cytotoxicity) of various oxygen, nitrogen, sulfur and platinum-containing derivatives of allobetulin, including different arrangements of the double bonds in the A and B rings, penta- and hexacyclic ring A, 21-acetyl-20,28-epoxy-18á,19âH-ursane-isomeric cycle ... | ['Cell Proliferation', 'Drug Screening Assays, Antitumor', 'Hep G2 Cells', 'Humans', 'Molecular Structure', 'Structure-Activity Relationship', 'Triterpenes'] | 25,895,356 | [['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['G02.111.830', 'G07.690.773.997'], ['D02.455.849.919']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Nuchal translucency measurement--the effect of 3D/4D ultrasound]. | INTRODUCTION: Nuchal translucency thickness has undoubtedly been proven as an important marker in screening for chromosomal abnormalities. It is measured in the first trimester by ultrasound. This study was aimed at determining the effect of 3D/4D ultrasound on standard error of mean nuchal translucency measurements.MA... | ['Adult', 'Chromosome Disorders', 'Crown-Rump Length', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Nuchal Translucency Measurement', 'Pregnancy', 'Sensitivity and Specificity', 'Ultrasonography, Prenatal'] | 23,653,992 | [['M01.060.116'], ['C16.131.260', 'C16.320.180'], ['E01.370.600.115.100.160.100.500', 'E05.041.124.160.500.500', 'G07.100.100.160.100.500', 'G07.100.100.250', 'N06.850.505.200.100.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.850.865.500', 'E01.370.378.630... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Racial differences in kidney function among individuals with obesity and metabolic syndrome: results from the Kidney Early Evaluation Program (KEEP). | BACKGROUND: Obesity and metabolic syndrome may differ by race. For participants in the National Kidney Foundation's Kidney Early Evaluation Program (KEEP), we examined whether African American and white participants with obesity and metabolic syndrome differ regarding albuminuria, estimated glomerular filtration rate (... | ['Adult', 'African Americans', 'Aged', 'Cohort Studies', 'Community Health Services', 'Continental Population Groups', 'European Continental Ancestry Group', 'Female', 'Foundations', 'Humans', 'Kidney', 'Kidney Diseases', 'Kidney Function Tests', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Obesity', 'Risk Factors', '... | 20,172,446 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N02.421.143'], ['M01.686.508'], ['M01.686.508.400'], ['N03.219.483.311', 'N03.540.630.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prevalence and abundance of latently transcribed varicella-zoster virus genes in human ganglia. | In human ganglia latently infected with varicella-zoster virus (VZV), sequence analysis has revealed that five viral genes (VZV genes 21, 29, 62, 63, and 66) are transcribed. However, their comparative prevalence and abundance are unknown. Here, using real-time PCR, we analyzed 28 trigeminal ganglia from 14 humans for ... | ['Adult', 'Aged', 'Aged, 80 and over', 'DNA, Complementary', 'DNA, Viral', 'Female', 'Genes, Viral', 'Herpesvirus 3, Human', 'Humans', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'RNA, Messenger', 'Sequence Analysis, DNA', 'Transcription, Genetic', 'Trigeminal Ganglion', 'Virus Latency'] | 17,192,313 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D13.444.308.568'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['B04.280.382.100.900.460'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biocatalysis of linoleic acid to conjugated linoleic acid. | CLA refers to a group of geometrical and positional isomers of linoleic acid (LA) with conjugated double bonds. CLA has been reported to have diverse health benefits and biological properties. Traditional organic synthesis is highly capital-intensive and results in an isomeric mixture of CLA isomers. Biotechnology pres... | ['Lactobacillus acidophilus', 'Linoleic Acid', 'Linoleic Acids, Conjugated'] | 17,120,931 | [['B03.353.750.450.475.100', 'B03.510.460.400.410.475.475.100', 'B03.510.550.450.475.100'], ['D10.251.355.310.515.500', 'D10.251.355.343.500.500'], ['D10.251.355.343.500.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of glucose on Ehrlich cell volume, ion transport, and membrane potential. | Incubating Ehrlich ascites tumor cells with 10 mM glucose at room temperature resulted in the following changes. The cells shrank, reaching a minimum volume after 1 h. The decrease in cell volume was 50-90% inhibited by 1 mM furosemide. The mmol K+ and Cl-/mg dry wt decreased, and mmol Na+/mg dry wt increased over the ... | ['Animals', 'Biological Transport', 'Carcinoma, Ehrlich Tumor', 'Chlorine', 'Fluorescence', 'Furosemide', 'Glucose', 'Ions', 'Membrane Potentials', 'Radioisotopes', 'Rubidium', 'Sodium Radioisotopes'] | 7,081,426 | [['B01.050'], ['G03.143'], ['C04.557.470.200.200', 'C04.619.169'], ['D01.268.380.150', 'D01.362.225'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['D09.947.875.359.448'], ['D01.248.497'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of efficacy in crossing femoropopliteal artery occlusions with movable core and hydrophilic guidewires. | PURPOSE: Compare the recanalization rate of femoropopliteal occlusions between movable core wire guide (MG) and hydrophilic guidewire (HG).METHODS: Conventional PTA technique was used, followed by enclosed thrombolysis. The MG was used for all patients in the first 2 years, the HG in the following 2 years. Baseline cha... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angioplasty, Balloon', 'Arterial Occlusive Diseases', 'Female', 'Femoral Artery', 'Humans', 'Male', 'Middle Aged', 'Popliteal Artery', 'Prospective Studies', 'Thrombolytic Therapy'] | 7,882,399 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.137'], ['A07.015.114.351'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.015.114.681'], ['E05.318.372.500.750.625', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Beyond the bloody mess: hematologic assessment. | Hematologic assessment is part of the routine assessment of acute and critically ill patients. Nurses must be aware of the reference ranges for complete blood cell counts and common coagulation profiles. A case study is presented of an elderly patient, taking warfarin for atrial fibrillation, who falls and sustains a h... | ['Accidental Falls', 'Aged', 'Blood Coagulation Tests', 'Erythrocyte Count', 'Female', 'Hematocrit', 'Hemoglobins', 'Hemorrhage', 'Humans', 'Platelet Count', 'Reference Standards', 'Risk Factors', 'Vitamin K', 'Warfarin'] | 23,027,790 | [['N06.850.135.122'], ['M01.060.116.100'], ['E01.370.225.625.115', 'E05.200.625.115'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.330', 'E05.242.195.107.330', 'G04.140.107.330', 'G09.188.105.330'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'],... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation of a cDNA encoding an Arabidopsis galactokinase by functional expression in yeast. | A cDNA clone encoding Arabidopsis thaliana galactokinase was fortuitously isolated during the course of a screen for plant homologues of a Saccharomyces cerevisiae peroxisome assembly gene, PAS9. Clones were sought which restored the ability of pas9 cells to grow on oleate as a sole carbon source, as oleate metabolism ... | ['Amino Acid Sequence', 'Arabidopsis', 'Cloning, Molecular', 'DNA, Complementary', 'Galactokinase', 'Gene Library', 'Humans', 'Molecular Sequence Data', 'Oleic Acid', 'Saccharomyces cerevisiae', 'Sequence Alignment', 'Sequence Homology, Amino Acid'] | 9,225,860 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D08.811.913.696.620.240'], ['G05.360.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D10.251.355.325.600.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prunella stica inhibits the proliferation but not the prostaglandin production of Ishikawa cells. | Chinese herbs have been used to relieve dysmenorrhea associated with endometriosis. Active components in the herbs and their mechanisms of action remain unknown. Prunella stica, a Chinese herb commonly used to treat dysmenorrhea, was chosen for the present studies. Its effects were investigated on Ishikawa cells, an ep... | ['Cell Proliferation', 'Cells, Cultured', 'Cyclooxygenase 2', 'Drugs, Chinese Herbal', 'Endometrium', 'Epithelial Cells', 'Female', 'Humans', 'Interleukin-1', 'Plant Structures', 'Prostaglandins', 'Prunella'] | 16,481,008 | [['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D08.811.600.720.750'], ['D20.215.784.500.350', 'D26.335'], ['A05.360.319.679.490'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of liver volume in vivo in rats using MRI. | Accurate estimation of the liver volume may be important for the diagnosis of several pathological processes in patients and for the study of new therapies in experimental oncology. Although sonography and computed tomography (CT) have been used for this purpose in patients, the lack of spatial resolution and tissue di... | ['Animals', 'Humans', 'Liver', 'Magnetic Resonance Imaging', 'Male', 'Models, Structural', 'Rats'] | 2,265,627 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E01.370.350.825.500'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Sex, germs, and health: pathogen-avoidance motives and health-protective behaviour. | OBJECTIVE: Recent work suggests that the psychology of pathogen-avoidance has wide-reaching effects on how people interact with the world. These processes - part of what has been referred to as the behavioural immune system - are, in a way, our 'evolved' health psychology. However, scholars have scarcely investigated h... | ['Adolescent', 'Adult', 'Attitude to Health', 'Avoidance Learning', 'Cross-Sectional Studies', 'Female', 'Health Behavior', 'Humans', 'Intention', 'Male', 'Mass Screening', 'Motivation', 'Self Report', 'Sexual Behavior', 'Sexual Partners', 'Sexually Transmitted Diseases', 'Young Adult'] | 26,953,783 | [['M01.060.057'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['F02.463.425.097', 'F02.463.785.373.173'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['E01.370.500', 'E05.318.308.980... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Design, synthesis, and pharmacological characterization of polyamine toxin derivatives: potent ligands for the pore-forming region of AMPA receptors. | Polyamine toxins, such as philanthotoxins, are low-molecular-weight compounds isolated from spiders and wasps, which modulate ligand-gated ion channels in the nervous system. Philanthotoxins bind to the pore-forming region of AMPA receptors, a subtype of glutamate receptors which are important for memory formation and ... | ['Animals', 'Chromatography, High Pressure Liquid', 'Drug Design', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Polyamines', 'Receptors, AMPA', 'Xenopus'] | 16,892,377 | [['B01.050'], ['E05.196.181.400.300'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D27.720.470.480'], ['E05.196.867.519'], ['D02.092.782'], ['D12.776.157.530.400.400.500.100', 'D12.776.543.550.450.500.200.100', 'D12.776.543.585.400.500.200.100', 'D12.776.543.750.720.200.450.400.100'], ['B01.050... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant. | Thrombin activates human platelets via 2 protease-activated receptors (PARs), PAR1 and PAR4, both of which are antithrombotic drug targets: a PAR1 inhibitor is approved for clinical use, and a PAR4 inhibitor is in trial. However, a common sequence variant in human PAR4 (rs773902, encoding Thr120 in place of Ala120) ren... | ['Amino Acid Substitution', 'Animals', 'Antibodies, Blocking', 'Antibodies, Monoclonal, Murine-Derived', 'Blood Platelets', 'Female', 'Fibrinolytic Agents', 'Humans', 'Male', 'Mice', 'Mutation, Missense', 'Platelet Aggregation', 'Receptors, Thrombin', 'Thrombin'] | 29,884,748 | [['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D12.776.124.486.485.114.143', 'D12.776.124.790.651.114.143', 'D12.776.377.715.548.114.143'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['A11.118.188', 'A15.145.229.188'], ['D27.505.519.421.750', 'D27... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. | Biochemical studies in vertebrate olfactory tissue indicate that certain odorants stimulate adenylyl cyclase in a GTP-dependent manner. Additionally, immunochemical and toxin-labeling studies demonstrate the presence of several GTP-binding protein (G-protein) species in vertebrate olfactory epithelium. To identify the ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cattle', 'Central Nervous System', 'Cloning, Molecular', 'DNA', 'DNA Restriction Enzymes', 'Epithelium', 'GTP-Binding Proteins', 'Genes', 'Membrane Proteins', 'Molecular Sequence Data', 'Olfactory Pathways', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains', 'Sequence... | 2,820,999 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.500.380.271'], ['A08.186'], ['E05.393.220'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['A10.272'], ['D08.811.277.040.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Histological mixed-type as an independent prognostic factor in stage I gastric carcinoma. | AIM: To evaluate the clinicopathological features of mixed-type gastric cancer and their influence on prognosis of mixed-type stage I gastric cancer.METHODS: We analyzed 446 patients who underwent curative gastrectomy for stage I gastric cancer between 1999 and 2009. The patients were divided into two groups: those wit... | ['Aged', 'Cell Differentiation', 'Chi-Square Distribution', 'Female', 'Gastrectomy', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Staging', 'Neoplasms, Complex and Mixed', 'Proportional Hazards Models', 'Retrospective Studies', 'Risk Factors', 'Stomach Neoplasms', 'Time F... | 25,593,472 | [['M01.060.116.100'], ['G04.152'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['E05.318.740.150.500', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anatomy of the tricuspid annulus. Circumferential myofibers as the structural basis for atrial flutter in a canine model. | BACKGROUND: Little anatomic information is available on the annular myocardium. This study was conducted to determine the anatomic substrate for atrial flutter due to circus movement around the tricuspid annulus in the Y-shaped incision canine model of atrial flutter.METHODS AND RESULTS: We studied photographs of the a... | ['Animals', 'Atrial Flutter', 'Dogs', 'Heart', 'Heart Atria', 'Heart Ventricles', 'Histological Techniques', 'Tricuspid Valve'] | 1,860,226 | [['B01.050'], ['C14.280.067.248', 'C23.550.073.248'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541'], ['A07.541.358'], ['A07.541.560'], ['E01.370.225.750', 'E05.200.750'], ['A07.541.510.893']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coordination of RNA Polymerase II Pausing and 3' End Processing Factor Recruitment with Alternative Polyadenylation. | Most mammalian genes produce transcripts whose 3' ends are processed at multiple alternative positions by cleavage/polyadenylation (CPA). Poly(A) site cleavage frequently occurs cotranscriptionally and is facilitated by CPA factor binding to the RNA polymerase II (Pol II) C-terminal domain (CTD) phosphorylated on Ser2 ... | ['Animals', 'Cell Line', 'Immunoglobulin M', 'Mice', 'Poly A', 'Polyadenylation', 'Protein Structure, Tertiary', 'RNA Polymerase II', 'RNA, Messenger', 'Transcriptional Activation', 'mRNA Cleavage and Polyadenylation Factors'] | 26,527,620 | [['B01.050'], ['A11.251.210'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.377.715.548.114.619.574'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.695.578.550.500'], ['G02.111.760.225.710', 'G03.839.225.710', 'G05.308.700.225.710'], ['G02.111.570.820.709.610'], ['D08.811.913.69... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anemia in adolescence. 2. Hemoglobinopathies and other causes. | Many complex forces are at work during adolescence which can contribute to the occurrence of anemia. Careful consideration of the entire patient should enable a physician to identify the unusual as well as the more common causes of anemia in this age group. Anemia in teenage girls is primarily due to menstrual iron los... | ['Adolescent', 'Age Factors', 'Anemia', 'Anemia, Hypochromic', 'Blood Transfusion', 'Contraceptives, Oral', 'Diet', 'Folic Acid Deficiency', 'Glucosephosphate Dehydrogenase Deficiency', 'Humans', 'Infectious Mononucleosis', 'Iron', 'Sickle Cell Trait', 'Substance-Related Disorders', 'Thalassemia'] | 1,109,736 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C15.378.071'], ['C15.378.071.196'], ['E02.095.135'], ['D27.505.696.875.360.276.210', 'D27.505.954.705.360.276.210'], ['G07.203.650.240'], ['C18.654.521.500.133.699.308'], ['C15.378.071.141.150.480', 'C16.320.070.480', 'C16.320.565.202.402', 'C18.452.648.202.40... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bone tissue engineering by using a combination of polymer/Bioglass composites with human adipose-derived stem cells. | Translational research in bone tissue engineering is essential for "bench to bedside" patient benefit. However, the ideal combination of stem cells and biomaterial scaffolds for bone repair/regeneration is still unclear. The aim of this study is to investigate the osteogenic capacity of a combination of poly(DL-lactic ... | ['Adipose Tissue', 'Alkaline Phosphatase', 'Animals', 'Bone and Bones', 'Cell Adhesion', 'Cell Proliferation', 'Cell Survival', 'Ceramics', 'Collagen', 'Humans', 'Immunohistochemistry', 'Lactic Acid', 'Male', 'Mice', 'Polyesters', 'Polymers', 'Stem Cell Transplantation', 'Stem Cells', 'Tissue Engineering', 'Tissue Scaf... | 24,408,074 | [['A10.165.114'], ['D08.811.277.352.650.035'], ['B01.050'], ['A02.835.232', 'A10.165.265'], ['G04.022'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['J01.637.153'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Association between second-generation antipsychotics and newly diagnosed treated diabetes mellitus: does the effect differ by dose? | BACKGROUND: The benefits of some second-generation antipsychotics (SGAs) must be weighed against the increased risk for diabetes mellitus. This study examines whether the association between SGAs and diabetes differs by dose.METHODS: Patients were ?18 years of age from three US healthcare systems and exposed to an SGA ... | ['Adolescent', 'Adult', 'Aged', 'Antipsychotic Agents', 'Diabetes Mellitus', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychotic Disorders'] | 22,171,594 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['C18.452.394.750', 'C19.246'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.700.675']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of Corneal Biomechanical Characteristics After Surface Ablation Refractive Surgery and Novel Lamellar Refractive Surgery. | PURPOSE: To investigate and compare corneal biomechanical changes in the form of corneal hysteresis (CH) and corneal resistance factor (CRF) after small-incision lenticule extraction (SMILE) and laser-assisted subepithelial keratectomy (LASEK).METHODS: In this retrospective observational study, patients who underwent e... | ['Adolescent', 'Adult', 'Biomechanical Phenomena', 'Cornea', 'Corneal Stroma', 'Corneal Topography', 'Diagnostic Techniques, Ophthalmological', 'Elasticity', 'Female', 'Humans', 'Intraocular Pressure', 'Keratectomy, Subepithelial, Laser-Assisted', 'Lasers, Excimer', 'Male', 'Myopia', 'Retrospective Studies', 'Young Adu... | 26,226,471 | [['M01.060.057'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['A09.371.060.217'], ['A09.371.060.217.228'], ['E01.370.380.150'], ['E01.370.380'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E02.594.480.500', 'E04.014.520.480.500', 'E04.378.500.500', 'E04.540.825.437.249'], ['E0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
alpha-Tocopherol disturbs macrophage LXRalpha regulation of ABCA1/G1 and cholesterol handling. | Based on the oxidation hypothesis high doses of alpha-tocopherol have been advocated to prevent atherosclerosis, but clinical trials failed to demonstrate a benefit. As specific oxylipids activate PPARgamma and LXRalpha, master regulators of lipid metabolism and cholesterol exporters, we hypothesized, that high dose al... | ['ATP Binding Cassette Transporter 1', 'ATP Binding Cassette Transporter, Subfamily G, Member 1', 'ATP-Binding Cassette Transporters', 'Antioxidants', 'Atherosclerosis', 'CD36 Antigens', 'Cholesterol', 'Cholesterol, HDL', 'DNA-Binding Proteins', 'Foam Cells', 'Genes, Reporter', 'Humans', 'Lipoproteins, LDL', 'Liver X R... | 18,328,805 | [['D12.776.157.530.100.050.500', 'D12.776.395.550.020.381.500', 'D12.776.543.550.192.381.500', 'D12.776.543.585.100.190.500'], ['D12.776.157.530.100.228.250', 'D12.776.395.550.020.457.250', 'D12.776.543.550.192.457.250', 'D12.776.543.585.100.228.250'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polyamine involvement in basal and estradiol-stimulated insulin-like growth factor I secretion and action in breast cancer cells in culture. | Recent evidence indicates that the polyamine pathway may play a significant role in the autocrine/paracrine control of breast cancer cell proliferation by hormones. To directly test this hypothesis, in the present experiments, we evaluated the polyamine involvement in immunoactive insulin-like growth factor I (IGF-I) s... | ['Antibodies, Monoclonal', 'Breast Neoplasms', 'Cell Transformation, Neoplastic', 'Eflornithine', 'Estradiol', 'Humans', 'Insulin-Like Growth Factor I', 'Ornithine Decarboxylase', 'Polyamines', 'Putrescine', 'Spermidine', 'Spermine', 'Tumor Cells, Cultured'] | 2,242,341 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C04.588.180', 'C17.800.090.500'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D12.125.068.665.340', 'D12.125.095.765.340'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.988.400.112.40... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice. | To elucidate the role of neuropeptide Y (NPY)-Y1 receptor (Y1-R) in food intake, energy expenditure, and other possible functions, we have generated Y1-R-deficient mice (Y1-R-/-) by gene targeting. Contrary to our hypothesis that the lack of NPY signaling via Y1-R would result in impaired feeding and weight loss, Y1-R-... | ['Animals', 'Blood Glucose', 'Body Temperature', 'Body Weight', 'Cardiopulmonary Resuscitation', 'Chimera', 'Feeding Behavior', 'Female', 'Genomic Library', 'Glucose Tolerance Test', 'Hyperinsulinism', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred Strains', 'Mice, Knockout', 'Obesity', 'Receptors, Neuropeptide Y'... | 9,861,026 | [['B01.050'], ['D09.947.875.359.448.500'], ['E01.370.600.875.374', 'G07.110'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E02.365.647.110'], ['B05.200'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['G05.360.325.425', 'G05.360.340.42... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Quantitative cineradiologic study of antral motility]. | The quantitative determination of antral motility from X-ray pictures was studied in 12 normal fasting subjects whose average age was 25. A sequence of 10 pictures was obtained while the subjects were lying prone, in apnea during 30 sec, and after drinking a barium sulfate suspension. The sinus and antral surfaces were... | ['Adult', 'Gastrointestinal Motility', 'Humans', 'Kinetics', 'Pyloric Antrum', 'Radiography'] | 7,349,472 | [['M01.060.116'], ['G10.261.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A03.556.875.875.716'], ['E01.370.350.700']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An áIIb mutation in patients with Glanzmann thrombasthenia located in the N-terminus of blade 1 of the â-propeller (Asn2Asp) disrupts a calcium binding site in blade 6. | BACKGROUND: Studies of Glanzmann thrombasthenia (GT)-causing mutations has generated invaluable information on the formation and function of integrin áIIbâ(3).OBJECTIVE: To characterize the mutation in four siblings of an Israeli Arab family affected by GT, and to analyze the relationships between the mutant protein st... | ['Adolescent', 'Amino Acid Sequence', 'Animals', 'Arabs', 'Asparagine', 'Aspartic Acid', 'Binding Sites', 'Blood Platelets', 'Calcium', 'Cell Line', 'Child', 'Child, Preschool', 'Cricetinae', 'DNA Mutational Analysis', 'Female', 'Genetic Predisposition to Disease', 'Glutamine', 'Hemostasis', 'Heredity', 'Humans', 'Hydr... | 21,029,361 | [['M01.060.057'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['M01.686.754.167'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['G02.111.570.120'], ['A11.118.188', 'A15.145.229.188'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Mid-term results of leaflet augmentation in severe tricuspid functional tethering. | OBJECTIVES: Functional tricuspid regurgitation (FTR) is usually managed surgically using various types of annuloplasty. FTR has been reported to recur in up to 45% of patients, with severe leaflet tethering being an important risk factor for recurrence. The aim of this study is to report the clinical and echocardiograp... | ['Aged', 'Belgium', 'Cardiac Valve Annuloplasty', 'Echocardiography', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index', 'Survival Rate', 'Time Factors', 'Tricuspid Valve', 'Tricuspid Valve Insufficiency'] | 26,922,815 | [['M01.060.116.100'], ['Z01.542.115'], ['E04.100.376.062', 'E04.928.220.109'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.937'], ['E05.318... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
TomExpress, a unified tomato RNA-Seq platform for visualization of expression data, clustering and correlation networks. | The TomExpress platform was developed to provide the tomato research community with a browser and integrated web tools for public RNA-Seq data visualization and data mining. To avoid major biases that can result from the use of different mapping and statistical processing methods, RNA-Seq raw sequence data available in... | ['Cluster Analysis', 'Data Mining', 'Databases, Genetic', 'Genome, Plant', 'Internet', 'Lycopersicon esculentum', 'RNA, Plant', 'Sequence Analysis, RNA', 'Web Browser'] | 28,873,253 | [['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.313.500.750.280.199', 'L01.470.625'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.360.340.365'], ['L01.224.230.110.500'], ['B01.650.940.800.575.912.250.908.500.322'], ['D13.444.735.635'], ['E05.393.760.710'], ['L01.224.900.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Empathic processes: perception by medical students of patients' anxiety and depression. | Perceptions by medical students of patients' affective states were investigated, and the effect of the students' own emotions on such perceptions. One hundred and one fourth-year medical students rated the levels of anxiety and depression of three women patients presented on videotape, rated their own levels of anxiety... | ['Anxiety', 'Depression', 'Education, Medical, Undergraduate', 'Empathy', 'Female', 'Humans', 'New Zealand', 'Physician-Patient Relations', 'Psychology', 'Self-Assessment', 'Social Perception', 'Students, Medical'] | 3,357,441 | [['F01.470.132'], ['F01.145.126.350'], ['I02.358.399.450'], ['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.678.100.747'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F04.096.628'], ['F01.752.747.792.537'], ['F02.463.593.752'], ['M01.848.769.602']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Aneurysmal dilatation of a patent umbilical vein masquerading as a pancreatic pseudocyst: CT characteristics. | A large cystic mass in a jaundiced patient had the appearance by sonography of a pancreatic pseudocyst. Computed tomography showed that the mass represented an aneurysmally dilated patent umbilical vein. | ['Adult', 'Aneurysm', 'Diagnosis, Differential', 'Dilatation, Pathologic', 'Humans', 'Male', 'Pancreatic Cyst', 'Pancreatic Pseudocyst', 'Tomography, X-Ray Computed', 'Umbilical Veins'] | 3,392,273 | [['M01.060.116'], ['C14.907.055'], ['E01.171'], ['C23.300.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.182.640', 'C06.689.500'], ['C04.182.640.692', 'C06.689.500.692'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Some claustro-cortical connections in the cat and baboon as studied by retrograde horseradish peroxidase transport. | 1. The mammalian Claustrum (Cl) is a convergent multisensory structure of unknown function, and disputed ontogenetic origin. Its cortical projections, hitherto unknown, have been studied in cat and baboon by means of the horseradish peroxidase (HRP) technique. HRP was injected into the gyrus proreus (frontal eye field)... | ['Animals', 'Basal Ganglia', 'Cats', 'Cerebral Cortex', 'Haplorhini', 'Motor Cortex', 'Neural Pathways', 'Papio', 'Visual Cortex', 'Visual Perception'] | 412,882 | [['B01.050'], ['A08.186.211.200.885.287.249'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.988.400'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['A08.612'], ['B01.050.150.900.649.313.988.400.112.199.120.610'], ['A08.18... | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effect of imizin on the circadian rhythm of rat motor activity taking into account its administration schedules]. | Chronic administration of imizine to rats irrespective of the administration schedule (once a day in the morning or in the evening in a dose of 10 mg/kg, twice a day in a dose of 5 mg/kg) changed the circadian rhythm of rest-activity with a shift of the acrophase at the late night hours. However at a single administrat... | ['Animals', 'Circadian Rhythm', 'Dose-Response Relationship, Drug', 'Female', 'Imipramine', 'Male', 'Motor Activity', 'Rats', 'Time Factors'] | 2,625,144 | [['B01.050'], ['G07.180.562.190'], ['G07.690.773.875', 'G07.690.936.500'], ['D03.633.300.240.485'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.992.635.505.700'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A high precision dual feedback pump for unsteady perfusion of small organs. | A dynamic pump system is described for perfusion of small organs with whole blood. The pump system was designed with the following aims: Very low flowrates to perfuse single organs in small rodents; high dynamic response for pressure or flow to permit experimenting with a harmonic signal at frequencies up to 20 Hz or b... | ['Animals', 'Equipment Design', 'Infusion Pumps', 'Perfusion', 'Pressure', 'Pulsatile Flow', 'Rodentia'] | 2,735,584 | [['B01.050'], ['E05.320'], ['E07.505', 'E07.858.082.505'], ['E05.680'], ['G01.374.715'], ['G01.482.620', 'G09.330.380.630.555'], ['B01.050.150.900.649.313.992']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
African ancestry protects against Alzheimer's disease-related neuropathology. | Previous studies in dementia epidemiology have reported higher Alzheimer's disease rates in African-Americans when compared with White Americans. To determine whether genetically determined African ancestry is associated with neuropathological changes commonly associated with dementia, we analyzed a population-based br... | ['African Continental Ancestry Group', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Apolipoproteins E', 'Brain Infarction', 'Brazil', 'Female', 'Gene-Environment Interaction', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Nervous System Diseases', 'Neurofibrillary Tangles', 'Odds Ratio', 'Plaque, Amyloid', 'Retro... | 22,064,377 | [['M01.686.508.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250'... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Imbalance between the endothelial cell-derived contracting factors prostacyclin and angiotensin II and nitric oxide/cyclic GMP in human primary varicosis. | 1. The role of the endothelium in the vasomotor control of human veins in the lower extremity is little understood. We tested the hypothesis that the production of relaxing and contracting factors is altered in endothelial cells from varicose saphenous veins which may predispose to the decreased vessel tone observed in... | ['Adult', 'Angiotensin II', 'Culture Media, Conditioned', 'Cyclic GMP', 'Endothelins', 'Endothelium, Vascular', 'Epoprostenol', 'Female', 'Humans', 'Muscle Contraction', 'Nitric Oxide', 'Nitroprusside', 'Varicose Veins'] | 9,375,976 | [['M01.060.116'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D27.720.470.305.250', 'E07.206.250'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D12.644.276.400', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enzymatic synthesis of a CCK-4 tripeptide fragment. | OBJECTIVE: To synthesize a tripeptide derivative Phac-Met-Asp(OMe)-Phe -NH2, which is a fragment of the gastrin C-terminal tetrapeptide CCK-4, by enzymatic reaction.METHODS: Three free enzymes, alpha-chymotrypsin, papain and thermolysin from acyl donor Phac-Met-OCam was involved in three steps. The choice of appropriat... | ['Chymotrypsin', 'Papain', 'Peptide Fragments', 'Tetragastrin', 'Thermolysin'] | 12,697,455 | [['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['D08.811.277.656.262.500.585', 'D08.811.277.656.300.200.585'], ['D12.644.541'], ['D06.472.317.413.800', 'D12.644.456.830'], ['D08.811.277.656.300.480.827', 'D08.811.277.656.675.374.827']] | ['Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of caries excavation methods on the bond strength of etch-and-rinse and self-etch adhesives to caries affected dentine. | BACKGROUND: The aim of this study was to evaluate the influence of chemomechanical caries removal and conventional caries excavation on the microtensile bond strength of three different dentine adhesive systems.METHODS: Thirty extracted human mandibular molars with radiographic signs of dental caries extending up to th... | ['Analysis of Variance', 'Bisphenol A-Glycidyl Methacrylate', 'Composite Resins', 'Dental Bonding', 'Dental Caries', 'Dental Etching', 'Dentin-Bonding Agents', 'Glutamic Acid', 'Humans', 'Leucine', 'Lysine', 'Mandible', 'Molar', 'Tensile Strength'] | 24,320,902 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D02.241.081.069.600.150', 'D02.455.426.559.389.657.100', 'D05.750.716.822.308.200', 'D25.339.816.500.200', 'D25.720.716.822.308.200', 'J01.637.051.339.816.500.200', 'J01.637.051.720.716.822.308.200'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Revision functional endoscopic sinus surgery: objective and subjective surgical outcomes. | BACKGROUND: The aim of this study was to report objective and subjective outcomes after revision sinus surgery (RESS) for chronic rhinosinusitis (CRS).METHODS: We performed a retrospective analysis of prospectively collected data in 125 patients requiring revision functional endoscopic sinus surgery after failing both ... | ['Adolescent', 'Adult', 'Aged', 'Asthma', 'Chronic Disease', 'Endoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nasal Polyps', 'Otorhinolaryngologic Surgical Procedures', 'Retrospective Studies', 'Rhinitis', 'Severity of Illness Index', 'Sinusitis', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 16,171,166 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C23.550.291.500'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C08.460.572', 'C09.603.557', 'C23.300.825.557'], ['E04.580'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Different molecular mechanisms of HTLV-1 and HIV LTR activation by TPA. | HTLV-1 and HIV-1 are retroviruses involved in different human diseases. However, following infection, these viruses inter into a latent state. Tax and Tat are regarded as trans-activators of HTLV-1 and HIV-1 respectively. As it known, during the latent state the infected cells contain low Tax and Tat protein levels, so... | ['Cyclic AMP Response Element-Binding Protein', 'Gene Expression Regulation, Viral', 'HIV Long Terminal Repeat', 'HIV-1', 'Human T-lymphotropic virus 1', 'Humans', 'Isoenzymes', 'Jurkat Cells', 'NF-kappa B', 'Protein Binding', 'Protein Kinase C', 'Terminal Repeat Sequences', 'Tetradecanoylphorbol Acetate', 'Transcripti... | 29,660,338 | [['D12.776.260.108.184', 'D12.776.930.127.184'], ['G05.308.385'], ['G02.111.570.080.708.850.400', 'G05.360.080.708.850.400'], ['B04.820.650.589.650.350.400'], ['B04.613.807.200.725.400', 'B04.820.650.200.725.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['A11.251.210.190.49... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Boric acid destabilizes the hyphal cytoskeleton and inhibits invasive growth of Candida albicans. | Exposure of Candida albicans to sub-lethal concentrations of boric acid (BA) restricts the dimorphic fungus to its yeast morphology and prevents the formation of invasive hyphae on solid substrates. Exposure to BA causes a rapid and reversible disappearance of polarisome and Spitzenk?rper in growing hyphae. In BA-treat... | ['Antifungal Agents', 'Boric Acids', 'Candida albicans', 'Cytoskeleton', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Hyphae'] | 25,612,315 | [['D27.505.954.122.136'], ['D01.029.260.093', 'D01.132.250', 'D02.203.130'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['A11.284.430.214.190.750'], ['D12.776.354'], ['G05.308.330'], ['A19.687.400']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical significance of preoperative nutritional status in 215 noncancer patients. | Preoperative nutritional status was assessed by: the percentage weight loss (% WL), body weight in relation to reference weight (WI), arm muscle circumference (AMC), and S-albumin (S-Alb) in a prospective study of 215 noncancer patients classified into three groups according to type of surgery: major vascular, minor va... | ['Abdomen', 'Age Factors', 'Anthropometry', 'Body Weight', 'Humans', 'Immunity, Cellular', 'Length of Stay', 'Nutrition Disorders', 'Nutritional Physiological Phenomena', 'Pilot Projects', 'Preoperative Care', 'Prognosis', 'Prospective Studies', 'Regression Analysis', 'Skin Tests', 'Surgical Procedures, Operative', 'Va... | 6,703,791 | [['A01.923.047'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.400'], ['E02.760.400.480', ... | ['Anatomy [A]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pathological, entomological, avian and meteorological investigation of a West Nile virus epidemic in a horse farm. | Pathological, entomological and avian investigations were conducted during the summer of 2002, in a horse farm that had four cases of West Nile virus (WNV) infection in horses. All the four horses had encephalitis and WNV infection was confirmed by RT-PCR and in situ hybridization procedure. Forty-seven per cent of hou... | ['Animals', 'Birds', 'Culex', 'Disease Outbreaks', 'Disease Reservoirs', 'Horse Diseases', 'Horses', 'Kentucky', 'Meteorological Concepts', 'RNA, Viral', 'Reverse Transcriptase Polymerase Chain Reaction', 'West Nile Fever', 'West Nile virus'] | 18,397,501 | [['B01.050'], ['B01.050.150.900.248'], ['B01.050.500.131.617.720.500.500.750.712.500.875.225'], ['N06.850.290'], ['N06.850.520.203.250'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['Z01.107.567.875.075.400', 'Z01.107.567.875.510.400'], ['G16.500.750', 'N06.230.300'], ['D13.444.735.828'], ['E05.393.620.500.7... | ['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Possible inhibitor from traditional Chinese medicine for the â form of calcium-dependent protein kinase type II in the treatment of major depressive disorder. | Recently, an important topic of major depressive disorder (MDD) had been published in 2013. MDD is one of the most prevalent and disabling mental disorders. Consequently, much research is being undertaken into the causes and treatment. It has been found that inhibition of the â form of calcium/calmodulin-dependent prot... | ['Calcium-Calmodulin-Dependent Protein Kinase Type 2', 'Depressive Disorder, Major', 'Drug Design', 'Enzyme Inhibitors', 'Humans', 'Ligands', 'Medicine, Chinese Traditional', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation'] | 25,045,698 | [['D08.811.913.696.620.682.700.125.200', 'D12.644.360.100.200', 'D12.776.476.100.200'], ['F03.600.300.375'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
Identity of the amino acid residues involved in C3bi binding to the I-domain supports a mosaic model to explain the broad ligand repertoire of integrin alpha M beta 2. | Interactions between the complement degradation product C3bi and leukocyte integrin alpha(M)beta(2) are critical for host defense against foreign pathogens and in tumor cell surveillance. To gain insight into the mechanism by which the alpha(M)I-domain of the integrin interacts with C3bi, detailed mapping of the C3bi b... | ['Amino Acid Sequence', 'Amino Acids', 'Complement C3b Inactivator Proteins', 'Ligands', 'Macrophage-1 Antigen', 'Models, Chemical', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Peptide Fragments', 'Point Mutation', 'Protein Binding', 'Protein Structure, Tertiary', 'Recombinant Fusion ... | 15,766,265 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['D12.776.124.486.274.920.325'], ['D27.720.470.480'], ['D12.776.543.750.705.408.495.500', 'D12.776.543.750.705.408.600.500', 'D12.776.543.750.705.833.500'], ['E05.599.495'], ['E05.599.595'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['D12.644.541'], ['G05.36... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chondrosarcoma of the larynx. | Two cases of laryngeal chondrosarcoma are described. The first exhibited a fibrosarcomatous differentiation, which is a rare finding in chondrosarcoma and usually indicates poor prognosis. The second was found in a larynx six years after Teflon injections for the treatment of vocal cord paralysis. The possibility of Te... | ['Aged', 'Chondrosarcoma', 'Humans', 'Laryngeal Neoplasms', 'Male', 'Middle Aged', 'Polytetrafluoroethylene'] | 2,721,410 | [['M01.060.116.100'], ['C04.557.450.565.280', 'C04.557.450.795.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['M01.060.116.630'], ['D05.750.395.616', 'D25.720.395.616', 'J01.637.051.720.395.616']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Chromosome analysis from peripheral blood lymphocytes of workers after an acute exposure to benzene. | A spillage of about 1200 gallons of benzene occurred during the loading of a ship, and 10 workers on a single shift were exposed to benzene. Shortly afterwards, an assay of the urine of these individuals showed that substantial amounts of phenol were being excreted. About three months after the incident samples of veno... | ['Accidents, Occupational', 'Benzene', 'Chromosome Aberrations', 'Crossing Over, Genetic', 'Environmental Exposure', 'Humans', 'Lymphocytes', 'Male', 'Occupational Medicine', 'Phenol', 'Phenols', 'Sister Chromatid Exchange', 'Time Factors'] | 6,722,051 | [['N06.850.135.240'], ['D02.455.426.559.389.023'], ['C23.550.210', 'G05.365.590.175'], ['G05.728.615.200'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['H02.403.720.750.510'], ['D02.455.426.559.389.657.595'], ['D02.455... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
First genetic evidence for the presence of the rumen fluke Paramphistomum epiclitum in Pakistan. | More than 70 species of the Superfamily Paramphistomoidea, have been identified in ruminants in different parts of the world. Most are pathogenic, causing amphistomosis. Adult flukes within this family have a predilection for the forestomach (rumen) or bile duct of the liver, where they may cause epithelial damage. Ide... | ['Animals', 'Buffaloes', 'Cattle', 'Cattle Diseases', 'DNA, Intergenic', 'Genetic Markers', 'Goat Diseases', 'Goats', 'Haplotypes', 'Pakistan', 'Paramphistomatidae', 'Parasite Egg Count', 'Phylogeny', 'Polymerase Chain Reaction', 'Rumen', 'Trematode Infections'] | 29,758,277 | [['B01.050'], ['B01.050.150.900.649.313.500.380.135'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['D13.444.308.324', 'G05.360.340.024.220'], ['D23.101.387', 'G05.695.450'], ['C22.405'], ['B01.050.150.900.649.313.500.380.513'], ['G05.380.360'], ['Z01.252.245.723'], ['B01.050.500.500.736.715.600'], ['E01.370.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Strength and lifetime of the bond between actin and skeletal muscle alpha-actinin studied with an optical trapping technique. | The force required to break the bond between skeletal muscle actin and alpha-actinin (unbinding force) was measured at the level of individual molecules with an optical trapping technique. An actin filament, to the barbed-end of which was attached a gelsolin-coated polystyrene bead, was bound to alpha-actinin molecules... | ['Actinin', 'Actins', 'Animals', 'Microscopy', 'Muscle, Skeletal', 'Protein Binding', 'Rabbits'] | 8,645,711 | [['D05.750.078.730.248', 'D12.776.210.500.095', 'D12.776.220.525.250'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['A02.633.567', 'A10.690.552.500'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.649.313.968.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
PH-controlled two dimensional gold nanoparticle aggregates for systematic study of local surface plasmon coupling. | We report a way of using citrates, ionic capping molecules on gold nanoparticles, as a "tuner" to adjust the charge density on the particles by solution pH, in correlation with their association constants (pKa). We have synthesized 10% biotin-capped gold nanoparticles with 90% citrates covering on the remaining surface... | ['Crystallization', 'Gold Colloid', 'Hydrogen-Ion Concentration', 'Macromolecular Substances', 'Materials Testing', 'Molecular Conformation', 'Nanoparticles', 'Nanostructures', 'Nanotechnology', 'Particle Size', 'Surface Plasmon Resonance', 'Surface Properties'] | 19,441,327 | [['E05.196.300', 'G02.171'], ['D01.379.400'], ['G02.300'], ['D05'], ['E05.570'], ['G02.111.570.820'], ['J01.637.512.600'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['G02.712'], ['E05.196.890', 'E05.601.043.700'], ['G02.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Adolescents' emotion expectancies regarding aggressive and nonaggressive events: connections with behavior problems. | A total of 50 behaviorally disruptive (conduct-disordered or oppositional defiant-disordered) adolescents and 50 comparison adolescents assessed how they expected to feel following both aggressive and nonaggressive situations. Compared with their peers, behaviorally disruptive adolescents expected fewer normative emoti... | ['Adolescent', 'Aggression', 'Attention Deficit and Disruptive Behavior Disorders', 'Awareness', 'Child Behavior Disorders', 'Education, Special', 'Emotions', 'Female', 'Humans', 'Individuality', 'Internal-External Control', 'Male', 'Personal Construct Theory', 'Poverty', 'Set, Psychology', 'Single-Parent Family', 'Urb... | 15,560,878 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['F03.625.094'], ['F02.463.188.150'], ['F03.625.141'], ['I02.233.213'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F01.829.379'], ['F02.739.660'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['F02.463.425.838'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Transient expression of the IL-2 receptor alpha-chain in IL-6-induced myeloid cells is regulated by autocrine production of prostaglandin E2. | The alpha-chain of the interleukin 2 receptor (IL-2R alpha) is expressed on monocytes and macrophages after activation by bacterial lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma). In the present study, we investigated whether the expression of IL-2R alpha is associated with the process of differentiation of ... | ['Animals', 'Bone Marrow', 'Bone Marrow Cells', 'Cell Differentiation', 'Dinoprostone', 'Flow Cytometry', 'Growth Inhibitors', 'Interleukin-6', 'Iodine Radioisotopes', 'Leukemia Inhibitory Factor', 'Leukemia, Myeloid', 'Lymphokines', 'Macrophages', 'Peptide Fragments', 'RNA, Messenger', 'Receptors, Interleukin-2', 'Tum... | 1,587,308 | [['B01.050'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['G04.152'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D27.505.696... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Case Report of Metronidazole-Induced Encephalopathy. | This report describes the case of an 83-year-old woman who was admitted to a hospitalist service with weakness and falls. She was transferred from an outside facility where she was treated with 3 courses of metronidazole for diagnosed Clostridium difficile colitis and presumed reoccurrences. Magnetic resonance imaging ... | ['Aged, 80 and over', 'Anti-Infective Agents', 'Brain Diseases', 'Clostridium Infections', 'Colitis', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Metronidazole'] | 29,357,212 | [['M01.060.116.100.080'], ['D27.505.954.122'], ['C10.228.140'], ['C01.150.252.410.222'], ['C06.405.205.265', 'C06.405.469.158.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['D02.640.672.500', 'D03.383.129.308.658.500']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ST-elevation myocardial infarction, thrombus aspiration, and different invasive strategies. A TASTE trial substudy. | BACKGROUND: The clinical effect of thrombus aspiration in ST-elevation myocardial infarction may depend on the type of aspiration catheter and stenting technique.METHODS AND RESULTS: The multicenter, prospective, randomized, open-label trial Thrombus Aspiration in ST-Elevation myocardial infarction in Scandinavia (TAST... | ['Aged', 'Cardiac Catheters', 'Coronary Thrombosis', 'Female', 'Humans', 'Male', 'Myocardial Infarction', 'Percutaneous Coronary Intervention', 'Stents', 'Thrombectomy', 'Treatment Outcome'] | 26,077,585 | [['M01.060.116.100'], ['E07.132.750.249'], ['C14.280.647.250.290', 'C14.907.355.830.220', 'C14.907.585.250.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['E04.100.814.529.968', 'E04.502.382.968'], ['E07.695.750'], ['E04.100.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mulberry (Morus alba L.) Fruit Extract Containing Anthocyanins Improves Glycemic Control and Insulin Sensitivity via Activation of AMP-Activated Protein Kinase in Diabetic C57BL/Ksj-db/db Mice. | The effect of mulberry (Morus alba L.) fruit extract (MFE) on hyperglycemia and insulin sensitivity in an animal model of type 2 diabetes was evaluated. C57BL/Ksj-diabetic db/db mice were divided into three groups: diabetic control, rosiglitazone, and MFE groups. Blood glucose, plasma insulin, and intraperitoneal gluco... | ['AMP-Activated Protein Kinases', 'Animals', 'Anthocyanins', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Diabetes Mellitus, Type 2', 'Dietary Supplements', 'Enzyme Activation', 'Fruit', 'Gluconeogenesis', 'Glucose Transporter Type 4', 'Glycated Hemoglobin A', 'Hyperglycemia', 'Hypoglycemic Agents', 'Insulin', ... | 27,441,957 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['B01.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Interactions between HIV-1 and cytomegalovirus in human osteosarcoma cells carrying both viruses. | Cytomegalovirus (CMV) and the human immunodeficiency virus type 1 (HIV-1) may interact in the pathogenesis of AIDS. We compared CMV replication in human osteosarcoma (HOS) cells to that in HOS cells genetically engineered to contain an envelope-deficient HIV-1 proviral construct (designated HOS-HXG). Following acute CM... | ['Antiviral Agents', 'Benzodiazepines', 'Cytomegalovirus', 'Drug Resistance, Microbial', 'Gene Products, env', 'Gene Products, tat', 'HIV-1', 'Humans', 'Mycophenolic Acid', 'Osteosarcoma', 'Proviruses', 'Pyrroles', 'Sequence Deletion', 'Superinfection', 'Tumor Cells, Cultured', 'Virus Replication', 'tat Gene Products, ... | 8,394,095 | [['D27.505.954.122.388'], ['D03.633.100.079.080'], ['B04.280.382.150.150'], ['G06.225', 'G07.690.773.984.269'], ['D12.776.775.320', 'D12.776.964.775.325', 'D12.776.964.970.880.325'], ['D12.776.260.755.199', 'D12.776.930.900.199', 'D12.776.964.900.750.750', 'D12.776.964.925.984.400'], ['B04.820.650.589.650.350.400'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary essential fatty acids change the fatty acid profile of rat neural mitochondria over time. | This experiment examined the time course over which the amount of dietary essential fatty acids (EFA) affects brain mitochondrial fatty acids. Weanling rats were fed 20% (wt/wt) fat diets that contained either 4 or 15% (wt/wt of diet) EFA for 1, 2, 3 or 6 wk or a 10% EFA diet for 3 or 6 wk. The EFA ratio [18:2(n-6)/18:... | ['Animals', 'Body Weight', 'Brain', 'Cardiolipins', 'Diet', 'Energy Intake', 'Fatty Acids, Essential', 'Male', 'Mitochondria', 'Organ Size', 'Phosphatidylcholines', 'Phosphatidylethanolamines', 'Rats', 'Rats, Inbred Strains'] | 1,765,818 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['D10.570.755.375.760.400.885.185', 'D23.050.550.480.330'], ['G07.203.650.240'], ['G07.203.650.240.340'], ['D10.251.355.310'], ['A11.284.430.214.190.875.564', 'A11.284.835.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The CMS Quality Roadmap: quality plus efficiency. | In addition to demonstrating wide variations in costs, resource inputs, and quality in California hospitals, John Wennberg and colleagues demonstrate that higher quality of care might be associated with increased delivery system efficiencies and lower costs. The Centers for Medicare and Medicaid Services (CMS) is attem... | ['California', 'Centers for Medicare and Medicaid Services, U.S.', 'Efficiency, Organizational', 'Hospitals', "Practice Patterns, Physicians'", 'Quality Assurance, Health Care', 'United States'] | 16,291,778 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['I01.409.418.750.600.310', 'N03.540.348.500.500.600.550'], ['N04.452.209.500'], ['N02.278.421'], ['N04.590.374.577', 'N05.300.625'], ['N04.761.700', 'N05.700'], ['Z01.107.567.875']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
p16INK4a polymorphism: associations with tumour progression in patients with sporadic colorectal cancer. | Deregulated tumour expression of p16INK4a has previously been described in association with clinical progression in sporadic colorectal cancer patients (CRC). Furthermore, p16INK4a promoter hypermethylation leading to gene silencing has been shown to occur in advanced colorectal tumours and has been associated with pat... | ['Colorectal Neoplasms', 'Disease Progression', 'Gene Expression Profiling', 'Genes, p16', 'Genotype', 'Humans', 'Linkage Disequilibrium', 'Neoplasm Staging', 'Polymorphism, Genetic', 'Prognosis', 'Survival Analysis'] | 15,492,837 | [['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['C23.550.291.656'], ['E05.393.332'], ['G05.360.340.024.340.375.249.375', 'G05.360.340.024.340.415.400.375'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Developing a sense of safety: the neurobiology of neonatal attachment. | Clinical data suggests a strong negative impact of traumatic attachments on adult mental illness, presumably through organizing brain development. To further explore this clinical issue, a mammalian model of imprinting was developed to characterize the neural basis of attachment in both healthy and traumatic attachment... | ['Amygdala', 'Child Development', 'Conditioning, Classical', 'Environment', 'Humans', 'Hydrocortisone', 'Infant', 'Infant Behavior', 'Infant, Newborn', 'Learning', 'Locus Coeruleus', 'Mother-Child Relations', 'Nerve Net', 'Norepinephrine', 'Object Attachment', 'Olfactory Bulb', 'Safety', 'Stress, Psychological'] | 14,998,878 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.425.179.308'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['M01.060.703'], ['F01.145.179.500... | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anaesthetic vapour concentrations in the EMO system. | Measurements of the vapour concentrations delivered by the EMO and Oxford Miniature Vaporizers (OMV) were made with both continuous (plenum mode) and intermittent (drawover mode) air flows. Leakage of ether, halothane and trichloroethylene vapours through the corrugated elephant tubing was also measured. Both vaporizer... | ['Adult', 'Anesthesia, Inhalation', 'Anesthetics', 'Ether', 'Halothane', 'Humans', 'Infant', 'Respiration', 'Trichloroethylene', 'Volatilization'] | 6,703,272 | [['M01.060.116'], ['E03.155.197.197'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['D02.355.417.332'], ['D02.455.526.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G09.772.705'], ['D02.455.526.439.939'], ['G01.645.750', 'G02.734.933']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Low N-ethylmaleimide concentrations activate ryanodine receptors by a reversible interaction, not an alkylation of critical thiols. | Previous studies proposed that N-ethylmaleimide (NEM) alkylates 3 classes of thiols on skeletal muscle ryanodine receptors (RyRs) producing 3 phases of channel modification, as function of time and concentration. NEM (5 mm) decreased, increased, and then decreased the open probability (P(o)) of the channel by thiol alk... | ['Alkylation', 'Animals', 'Calcium', 'Ethylmaleimide', 'Muscle, Skeletal', 'Nitric Oxide', 'Rabbits', 'Ruthenium Red', 'Ryanodine', 'Ryanodine Receptor Calcium Release Channel', 'Sarcoplasmic Reticulum', 'Sulfhydryl Compounds'] | 10,998,412 | [['G02.111.035', 'G02.607.094', 'G03.059'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.241.081.337.502.524.418', 'D02.478.440.418', 'D03.383.129.578.399.418'], ['A02.633.567', 'A10.690.552.500'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['B01.050.150.9... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Randomly connected networks generate emergent selectivity and predict decoding properties of large populations of neurons. | Modern recording methods enable sampling of thousands of neurons during the performance of behavioral tasks, raising the question of how recorded activity relates to theoretical models. In the context of decision making, functional connectivity between choice-selective cortical neurons was recently reported. The straig... | ['Action Potentials', 'Animals', 'Models, Neurological', 'Nerve Net', 'Neurons'] | 32,379,751 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E05.599.395.642'], ['A08.511'], ['A08.675', 'A11.671']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of morphological characteristics and texture analysis in the identification of tissue composition in prostatic neoplasia. | Quantitative examination of prostate histology offers clues in the diagnostic classification of lesions and in the prediction of response to treatment and prognosis. To facilitate the collection of quantitative data, the development of machine vision systems is necessary. This study explored the use of imaging for iden... | ['Humans', 'Image Processing, Computer-Assisted', 'Male', 'Prostatic Neoplasms', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 15,343,515 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750... | ['Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
What type of service provision do patients with chronic pain want from primary care providers? | PURPOSE: The aim of this study was to explore what types of service provision patients with chronic pain wanted from their general practitioners (GP).METHOD: A small scale survey measured anxiety and depression and quantified the extent to which patients wanted four different types of help from their GP (explanation an... | ['Adult', 'Aged', 'Case-Control Studies', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pain Management', 'Patient Preference', 'Physician-Patient Relations', 'Primary Health Care', 'Surveys and Questionnaires', 'Young Adult'] | 19,294,547 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.745', 'N04.590.607.500'], ['F01.100.150.750.625.500', 'F01.145.488.887.625.500', 'N04.452.822.700.500', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Optimizing injected dose in clinical PET by accurately modeling the counting-rate response functions specific to individual patient scans. | UNLABELLED: To optimize the injected dose of radiopharmaceutical in PET, one needs to know its relationship to some metric of data quality for individual patient scans, such as noise-equivalent counting rate (NECR). In this paper, we show how one may accurately model the clinical NECR response corresponding to specific... | ['Computer Simulation', 'Drug Administration Schedule', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Injections', 'Male', 'Models, Biological', 'Positron-Emission Tomography', 'Quality Assurance, Health Care', 'Radiopharmaceuticals', 'Reference Standards', 'Whole Body Imaging', '... | 16,269,596 | [['L01.224.160'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E02.319.267.530'], ['E05.599.395'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', '... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Biochemical and molecular characterization of a lipase produced by Rhizopus oryzae. | A novel strain of Rhizopus oryzae WPG secretes a noninduced lipase (ROLw) in the culture medium; purified ROLw is a protein of 29 kDa, the 45 N-terminal amino acid residues were sequenced, this sequence is very homologous to Rhizopus delemar lipase (RDL), Rhizopus niveus lipase (RNL) and R. oryzae lipase (ROL29) sequen... | ['Amino Acid Sequence', 'Cloning, Molecular', 'Enzyme Activation', 'Lipase', 'Molecular Sequence Data', 'Rhizopus', 'Sequence Analysis, DNA', 'Structure-Activity Relationship', 'Triglycerides'] | 16,842,350 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['G02.111.263', 'G03.328'], ['D08.811.277.352.100.400'], ['L01.453.245.667'], ['B01.300.300.500.800'], ['E05.393.760.700'], ['G02.111.830', 'G07.690.773.997'], ['D10.351.801']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Classification of Two Class Motor Imagery Tasks Using Hybrid GA-PSO Based K-Means Clustering. | Transferring the brain computer interface (BCI) from laboratory condition to meet the real world application needs BCI to be applied asynchronously without any time constraint. High level of dynamism in the electroencephalogram (EEG) signal reasons us to look toward evolutionary algorithm (EA). Motivated by these two f... | ['Adult', 'Algorithms', 'Brain', 'Brain Waves', 'Brain-Computer Interfaces', 'Cluster Analysis', 'Discriminant Analysis', 'Electroencephalography', 'Female', 'Humans', 'Imagination', 'Male', 'Movement', 'Signal Processing, Computer-Assisted', 'User-Computer Interface', 'Young Adult'] | 25,972,896 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['E01.370.376.300.150', 'E01.370.405.245.287', 'G07.265.087', 'G11.561.127'], ['E07.305.076'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['E01.370.376.300', 'E01.370... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Maternal hyperglycemia modifies extracellular matrix signaling pathways in neonatal rat lung. | BACKGROUND: Maternal diabetes is associated with numerous adverse effects in fetal and neonatal organs, including the lungs.OBJECTIVE: To investigate the effects of intrauterine hyperglycemia on neonatal lung biological signaling, we performed a microarray analysis in the lungs of four 14-day-old rat pups born to a hyp... | ['Animals', 'Animals, Newborn', 'Blood Glucose', 'Cell Adhesion', 'Cell Proliferation', 'Diabetes Mellitus, Experimental', 'Extracellular Matrix', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Hyperglycemia', 'Lactation', 'Lung', 'Maternal-Fetal Exchange', 'Oligonucleotide Array S... | 21,051,908 | [['B01.050'], ['B01.050.050.282'], ['D09.947.875.359.448.500'], ['G04.022'], ['G04.161.750', 'G07.345.249.410.750'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A11.284.295.310'], ['E05.393.332'], ['G05.308.310'], ['C18.452.394.952'], ['G08.686.523', 'G08.686.702.500'], ['A04.411'], ['G08.686.784.769.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of irreversible electroporation ablation in in vivo porcine liver. | OBJECTIVE: The purpose of this study was to prospectively characterize and optimize irreversible electroporation ablation to determine the best parameters to achieve the largest target zones of coagulation for two electrodes.MATERIALS AND METHODS: Ultrasound-guided irreversible electroporation ablation (n=110) was perf... | ['Animals', 'Electroporation', 'Female', 'Liver', 'Prospective Studies', 'Swine', 'Ultrasonography, Interventional'] | 22,194,517 | [['B01.050'], ['E05.200.500.454', 'E05.242.448', 'E05.301.500'], ['A03.620'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['B01.050.150.900.649.313.500.880'], ['E01.370.350.850.855', 'E04.502.890']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genetic and molecular analysis of the rpoD gene from Lactococcus lactis. | A gene of Lactococcus lactis ATCC19435, the product of which is homologous with the principal sigma factors of Escherichia coli and Bacillus subtilis, was cloned and sequenced. The deduced amino acid sequence of the 340-residue protein and the upstream open reading frame of the cloned gene showed a homology to B. subti... | ['Amino Acid Sequence', 'Bacillus subtilis', 'Bacterial Proteins', 'Base Sequence', 'Blotting, Southern', 'Cloning, Molecular', 'DNA Primase', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Genes, Bacterial', 'Genetic Complementation Test', 'Lactococcus lactis', 'Molecular Sequence Data', 'Mutation', 'Operon', 'R... | 7,503,808 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.15... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Bidirectional imaging and modeling of skin texture. | In this paper, we present a method of skin imaging called bidirectional imaging that captures significantly more properties of appearance than standard imaging. The observed structure of the skin's surface is greatly dependent on the angle of incident illumination and the angle of observation. Specific protocols to ach... | ['Algorithms', 'Artificial Intelligence', 'Databases, Factual', 'Humans', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Models, Biological', 'Pattern Recognition, Automated', 'Skin', 'Skin Diseases'] | 15,605,862 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.599.395'], ['L01.399.750'], ['A17.815'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Estrogenic and mutagenic activities of Crotalaria pallida measured by recombinant yeast assay and Ames test. | BACKGROUND: Crotalaria pallida Ailton is a plant belonging to the Fabaceae family, popularly known as "rattle or rattlesnake" and used in traditional medicine to treat swelling of the joints and as a vermifuge. Previous pharmacological studies have also reported anti-inflammatory, antimicrobial and antifungal activitie... | ['Antifungal Agents', 'Crotalaria', 'Microsomes', 'Mutagenicity Tests', 'Mutagens', 'Phytoestrogens', 'Plant Extracts', 'Plant Leaves', 'Saccharomyces cerevisiae', 'Salmonella typhimurium', 'Stigmasterol'] | 24,134,316 | [['D27.505.954.122.136'], ['B01.650.940.800.575.912.250.401.175'], ['A11.284.835.540'], ['E05.393.560', 'E05.940.560'], ['D27.888.569.468'], ['D27.505.696.399.472.277.540.500'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['B03.440.450.425.800.200.825', 'B03.660.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of occlusal splint therapy on blink reflex time in TMJ dysfunction patients. | This study compares the changes that occur in latency before and after use of splint therapy in patients with TMJ dysfunction. The sensory fibers of the upper branch of the trigeminal nerve were stimulated and the time required for the sensory and motor responses to occur were measured. A reduction in latency occurred ... | ['Blinking', 'Humans', 'Splints', 'Temporomandibular Joint Dysfunction Syndrome'] | 2,076,242 | [['G11.561.731.127', 'G14.152'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.858.442.660.430.750', 'E07.858.690.725.430.750'], ['C05.500.607.221.897.897', 'C05.550.905.905', 'C05.651.243.897.897', 'C05.651.550.905', 'C07.320.610.291.897.897', 'C07.678.949']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation. | Endotoxemia is caused by excessive inflammation, but the immune system has various mechanisms to avoid collateral organ damage in endotoxemia. A handful of reports have shown that innate immune responses are suppressed by the adaptive immune system. However, the molecular mechanism by which adaptive immune cells suppre... | ['Animals', 'Antigens, CD', 'Cell Nucleus', 'Down-Regulation', 'Inflammation', 'Interleukin-1 Receptor-Associated Kinases', 'Interleukin-10', 'Macrophages', 'Mice', 'Protein Transport', 'Signal Transduction', 'Sumoylation', 'T-Lymphocytes', 'Toll-Like Receptor 4', 'Tumor Necrosis Factor-alpha'] | 24,706,909 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['C23.550.470'], ['D08.811.913.696.620.682.700.526', 'D12.644.360.370', 'D12.776.476.384'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contribution of thickened drinks, food and enteral and parenteral fluids to fluid intake in hospitalised patients with dysphagia. | BACKGROUND: Studies amongst older people with acute dysphagic stroke requiring thickened fluids have assessed fluid intakes from combinations of beverage, food, enteral and parenteral sources, but not all sources simultaneously. The present study aimed to comprehensively assess total water intake from food, beverages, ... | ['Aged', 'Aged, 80 and over', 'Beverages', 'Deglutition Disorders', 'Dehydration', 'Diet', 'Drinking', 'Enteral Nutrition', 'Food', 'Hospitalization', 'Humans', 'Middle Aged', 'Parenteral Nutrition'] | 19,302,120 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.203.100', 'J02.200'], ['C06.405.117.119', 'C09.775.174'], ['C18.452.950.179', 'C23.550.274'], ['G07.203.650.240'], ['G07.203.650.283.249', 'G10.261.330.249'], ['E02.421.360', 'E02.642.500.360'], ['G07.203.300', 'J02.500'], ['E02.760.400', 'N02.421.585.400'], ['B01.05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Utilization for protein synthesis of 2-ketoisocaproate relative to utilization of leucine, as estimated from exhalation of labelled CO2. | 1. We have previously shown that the ratio (RWBP) of incorporation of label from 2-ketoisocaproate (KIC) into the leucine of whole-body protein to the simultaneous incorporation of label from leucine itself into protein is a measure of the nutritional efficiency of KIC as a substitute for leucine. 2. In order to determ... | ['Animals', 'Carbon Dioxide', 'Keto Acids', 'Leucine', 'Male', 'Oxidation-Reduction', 'Protein Biosynthesis', 'Rats', 'Rats, Inbred Strains'] | 3,138,058 | [['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D02.241.755'], ['D12.125.070.637', 'D12.125.142.441'], ['G02.700', 'G03.295.531'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spatial-temporal characteristics and driving factors of the human health impacts of five industrial aquatic toxic metals in China. | With the rapid advancement of industrialization without effective supervision, industrial aquatic toxic metal (TM) emissions pose threats to human health in China. Due to differences in socioeconomic development, the regional disparity of industrial aquatic TM emissions is obvious nationwide. In this study, the human h... | ['China', 'Environmental Health', 'Environmental Monitoring', 'Heavy Metal Poisoning', 'Humans', 'Industry', 'Mercury', 'Metals, Heavy', 'Water Pollutants'] | 32,300,920 | [['Z01.252.474.164'], ['H02.229'], ['N06.850.460.350.080', 'N06.850.780.375'], ['C25.723.522'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D01.268.556', 'D01.552.544'], ['D27.888.284.903']] | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Sequential changes in the numbers of B and T lymphocytes and other leukocytes in the blood in Marek's disease. | Numbers of B, T and total lymphocytes, monocytes, heterophils, eosinophils and basophils have been examined in the peripheral blood of chickens between 2 and 42 days after infection with Marek's disease virus. During the stage of the acute restrictively productive virus infection of lymphoid tissues at 2-9 days after i... | ['Acute Disease', 'Animals', 'B-Lymphocytes', 'Basophils', 'Chickens', 'Eosinophils', 'Female', 'Fluorescent Antibody Technique', 'Leukocyte Count', 'Leukocytes', 'Lymphoma', 'Male', 'Marek Disease', 'Monocytes', 'Sex Factors', 'T-Lymphocytes'] | 789,260 | [['C23.550.291.125'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A11.... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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