Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The blink reflex in patients with idiopathic torsion dystonia. | The blink reflex and its recovery cycle were examined in 57 patients with idiopathic dystonia affecting different parts of the body. The group comprised 9 patients with generalized and 15 with segmental forms, 19 with torticollis, and 14 with focal arm dystonia. None had blepharospasm. The duration and amplitude of the... | ['Arm', 'Blinking', 'Dystonia Musculorum Deformans', 'Female', 'Humans', 'Male', 'Reaction Time', 'Torticollis'] | 2,322,135 | [['A01.378.800.075'], ['G11.561.731.127', 'G14.152'], ['C10.228.140.079.357', 'C10.228.662.300.200', 'C10.574.500.393', 'C16.320.400.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['C23.888.592.350.300.800']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe ovarian hyperstimulation syndrome in a naturally conceived singleton pregnancy after ovulation induction: a case report. | OBJECTIVE: To present a case of severe ovarian hyperstimulation syndrome (OHSS) in a naturally conceived singleton pregnancy after ovulation induction.CASE: A 31-year-old woman with polycystic ovarian syndrome (PCOS) underwent ovulation induction therapy. Six days later, she was admitted to the present hospital with th... | ['Adult', 'Ascites', 'Female', 'Humans', 'Ovarian Hyperstimulation Syndrome', 'Ovulation Induction', 'Paracentesis', 'Patient Care Management', 'Patient Care Team', 'Polycystic Ovary Syndrome', 'Pregnancy', 'Severity of Illness Index', 'Treatment Outcome', 'Ultrasonography'] | 29,746,043 | [['M01.060.116'], ['C23.550.081'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.056.630.642', 'C19.391.630.642'], ['E02.875.800.984', 'E05.820.800.984'], ['E01.370.225.998.329', 'E02.309.805', 'E02.800.550', 'E04.237.667', 'E04.665.600', 'E05.200.998.329'], ['N04.590'], ['N04.590.715'], ['C04.182.612.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tracing the Potential Flow of Consumer Data: A Network Analysis of Prominent Health and Fitness Apps. | BACKGROUND: A great deal of consumer data, collected actively through consumer reporting or passively through sensors, is shared among apps. Developers increasingly allow their programs to communicate with other apps, sensors, and Web-based services, which are promoted as features to potential users. However, health ap... | ['Cross-Sectional Studies', 'Data Collection', 'Humans', 'Mobile Applications', 'Telemedicine'] | 28,659,254 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900.685'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Polyamines stimulate lysosomal cystine transport. | Lysosomal cystine transport is a carrier-dependent process that, in isolated lysosomes, is stimulated by proton gradients, membrane potential, and millimolar concentrations of divalent cations. The importance of these regulatory factors in vivo is not well established. Polyamines were found to stimulate cystine transpo... | ['Animals', 'Cadaverine', 'Cells, Cultured', 'Cystine', 'Hydrogen-Ion Concentration', 'Lysosomes', 'Membrane Potentials', 'Polyamines', 'Putrescine', 'Rats', 'Spermidine', 'Spermine'] | 3,680,256 | [['B01.050'], ['D02.092.211.415.261', 'D02.092.782.258.174'], ['A11.251'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.230.369'], ['G02.300'], ['A11.284.430.214.190.875.190.550'], ['G01.154.535', 'G04.580', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neutrophils become refractory to phorbol myristate acetate when treated with Ca2+-ionophore and Ca2+. | Human neutrophils deprived of divalent cations by treatment with ionophore A23187 in the presence of ethylene glycol bis(beta-aminoethylether)-N,N,N',N'-tetraacetic acid (EGTA) showed superoxide release when they were preincubated with calcium and then treated with the ionophore. The release was not observed when the i... | ['Aminoquinolines', 'Calcimycin', 'Calcium', 'Drug Resistance', 'Egtazic Acid', 'Humans', 'Neutrophils', 'Protein Kinase C', 'Superoxides', 'Tetradecanoylphorbol Acetate', 'Time Factors'] | 3,036,787 | [['D03.633.100.810.050'], ['D03.633.100.221.173'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.690.773.984'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.38... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The determinants of therapeutic levels of continuous positive airway pressure in elderly sleep apnea patients. | We have examined the role of age on the continuous positive airway pressure (CPAP) levels required to treat two groups of elderly (n=70) and young (n=70) sleep apneic patients, matched for disease severity (apnea/hypopnea index), body mass index and neck circumference. Elderly patients required lower CPAP levels compar... | ['Adult', 'Age Factors', 'Aged', 'Airway Resistance', 'Anthropometry', 'Continuous Positive Airway Pressure', 'Female', 'Humans', 'Lung Volume Measurements', 'Male', 'Neck', 'Severity of Illness Index', 'Sleep Apnea Syndromes'] | 16,318,915 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.386.700.050', 'G09.772.060'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485'], ['A01.598'], ['E05.318.3... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
<i>Capricornella</i> <i>bicornuta</i>, a new genus and species of mite from eastern Australia (Acari: Uropodina). | We describe a new genus and species of mite from eastern Australia, Capricornella bicornuta. The new genus is characterised by the presence of two long appendages on the anterior margin of the epigynal shield of the female. | ['Acari', 'Animals', 'Australia', 'Female', 'Mites'] | 28,610,108 | [['B01.050.500.131.166.132'], ['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.500.131.166.132.419']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Perception of scent over-marks by golden hamsters (Mesocricetus auratus): novel mechanisms for determining which individual's mark is on top. | Hamsters preferentially remember or value the top scent of a scent over-mark. What cues do they use to do this? Using habituation-discrimination techniques, we exposed male golden hamsters (Mesocricetus auratus) on 3 to 4 trials to genital over-marks from 2 females and then tested subjects for their familiarity with th... | ['Analysis of Variance', 'Animal Communication', 'Animals', 'Attention', 'Competitive Behavior', 'Cricetinae', 'Depth Perception', 'Discrimination, Psychological', 'Female', 'Habituation, Psychophysiologic', 'Male', 'Memory', 'Mesocricetus', 'Orientation', 'Sex Attractants', 'Sexual Behavior, Animal', 'Smell', 'Time Fa... | 9,770,313 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.145.113.055'], ['B01.050'], ['F02.830.104.214'], ['F01.145.813.105'], ['B01.050.150.900.649.313.992.635.075.250'], ['F02.463.593.200', 'F02.463.593.778.255'], ['F02.463.593.257'], ['F02.463.425.393', 'F02.830.422', 'G11.561.312'], ['F02.463.425.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Use of the KTP laser in totally endoscopic cholesteatoma surgery. | OBJECTIVE: This paper reviews our experience of potassium titanyl phosphate (KTP) laser in transcanal totally endoscopic cholesteatoma surgery.METHODS: A prospective cohort study was conducted in a tertiary referral centre, involving a consecutive series of children with cholesteatoma who underwent totally endoscopic c... | ['Adolescent', 'Child', 'Child, Preschool', 'Cholesteatoma, Middle Ear', 'Ear Canal', 'Endoscopy', 'Humans', 'Infant', 'Lasers, Solid-State', 'Minimally Invasive Surgical Procedures', 'Neoplasm, Residual', 'Prospective Studies', 'Treatment Outcome'] | 32,122,410 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C09.218.200', 'C17.800.428.260.300'], ['A09.246.272.396'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E07.632.490.490', 'E07.710.520.490'], ['E04.502'], ['C04.697.700', 'C23.550.727.700'], ['E05.318.37... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reduced awareness of hypoglycemia in adults with IDDM. A prospective study of hypoglycemic frequency and associated symptoms. | OBJECTIVE: To prospectively evaluate the frequency and severity of hypoglycemic episodes in IDDM subjects who declare themselves to have reduced awareness of hypoglycemia, to validate their self-designations in their natural environment, and to determine objectively the presence or absence of autonomic and neuroglycope... | ['Adult', 'Awareness', 'Blood Glucose', 'Diabetes Mellitus, Type 1', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemia', 'Male', 'Middle Aged', 'Prospective Studies', 'Self-Examination', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 7,497,862 | [['M01.060.116'], ['F02.463.188.150'], ['D09.947.875.359.448.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['M01.060.116.630'], ['E05.31... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Visibility of speech articulation enhances auditory phonetic convergence. | Talkers automatically imitate aspects of perceived speech, a phenomenon known as phonetic convergence. Talkers have previously been found to converge to auditory and visual speech information. Furthermore, talkers converge more to the speech of a conversational partner who is seen and heard, relative to one who is just... | ['Adult', 'Female', 'Humans', 'Male', 'Noise', 'Phonetics', 'Photic Stimulation', 'Speech', 'Speech Perception'] | 26,358,471 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['L01.559.598.518'], ['E05.723.729'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['F02.463.593.071.875', 'G07.888.125.875']] | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Pharmacologic hemostasis in laparoscopy: topical epinephrine facilitates cholecystectomy. | Bleeding may become a major impediment to accurate and safe dissection by laparoscopy. The traditional maneuvers of pressure, dumping, irrigation, and aspiration frequently applied during open procedures to maintain a clear field of dissection are cumbersome through laparoscopy. Several pharmacologic agents have been u... | ['Administration, Topical', 'Blood Loss, Surgical', 'Cholecystectomy, Laparoscopic', 'Epinephrine', 'Hemostasis, Surgical', 'Humans'] | 8,489,094 | [['E02.319.267.120'], ['C23.550.414.300', 'C23.550.505.300'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['E02.520.490', 'E04.350'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer. | Drug combination therapy is a key strategy to improve treatment efficacy and survival of cancer patients. In this study the effects of combining 2-methoxyoestradiol-3,17-O,O-bis-sulphamate (STX140), a microtubule disruptor, with 2-deoxy-D-glucose (2DG) were assessed in MCF-7 (breast) and LNCaP (prostate) xenograft mode... | ['Animals', 'Antineoplastic Combined Chemotherapy Protocols', 'Apoptosis', 'Breast Neoplasms', 'Cell Cycle', 'Cell Hypoxia', 'Cell Line, Tumor', 'Cell Proliferation', 'Deoxyglucose', 'Estrenes', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Mice', 'Mice, Nude', 'Prostatic Neoplasms', 'Xenograft Model Antitumor A... | 18,985,042 | [['B01.050'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['G04.144'], ['G03.197.300', 'G04.270.300'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D09.254.229'], ['D04.210.500.365.415'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Luteal phase contraception with mifepristone (RU 486) in the rhesus monkey. | Mifepristone (RU 486), an antiprogesterone, is a promising luteal phase contraceptive agent for human use. However, at present its use is limited by the practical constraint of determining the day of ovulation for an LH + 2 day administration of the drug as indicated from experimental and clinical studies. The aim of t... | ['Animals', 'Embryo Implantation', 'Estradiol', 'Female', 'Hormones', 'Luteal Phase', 'Macaca mulatta', 'Male', 'Menstruation', 'Mifepristone', 'Ovulation', 'Pregnancy', 'Progesterone'] | 8,132,238 | [['B01.050'], ['G08.686.784.170.104.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472', 'D27.505.696.399.472'], ['G08.686.605.410'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['G08.686.605.428'], ['D04.210.500.365.415.580'], ['G08.686.784.690'], ['G08.686.784.769'], ['D04.210.500.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
shRNA-mediated EMMPRIN silencing inhibits human leukemic monocyte lymphoma U937 cell proliferation and increases chemosensitivity to adriamycin. | EMMPRIN is a widely distributed cell surface glycoprotein, which plays an important role in tumor progression and confers resistance to some chemotherapeutic drugs. Recent studies have shown that EMMPRIN overexpression indicates poor prognosis in acute myeloid leukemia (AML). However, little was known on the role of EM... | ['Antineoplastic Agents', 'Apoptosis', 'Basigin', 'Cell Cycle Checkpoints', 'Cell Proliferation', 'Cell Survival', 'Doxorubicin', 'G1 Phase', 'Gene Expression Regulation, Neoplastic', 'Gene Knockdown Techniques', 'Gene Silencing', 'Humans', 'Leukemia', 'Lymphoma', 'RNA, Small Interfering', 'U937 Cells'] | 25,260,396 | [['D27.505.954.248'], ['G04.146.954.035'], ['D12.776.395.550.045', 'D12.776.543.550.187', 'D23.050.285.040'], ['G04.144.109'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['G04.144.500.320'], ['G05.308.370'], ['E05.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Collaborative investigations on thoron and radon in some rural communities of Balkans. | This paper deals with the results of the first-field use in the Balkans, i.e. Serbia and Republic of Srpska (Bosnia and Hercegovina), of a passive polycarbonate Mark II type and poliallyldiglycol carbonate (Cr-39) alpha track detectors sensitive to thoron as well as to radon. Both types of solid state nuclear track det... | ['Air Pollutants, Radioactive', 'Air Pollution', 'Bosnia and Herzegovina', 'Environmental Exposure', 'Equipment Design', 'Gases', 'Humans', 'Radiation Monitoring', 'Radiometry', 'Radon', 'Radon Daughters', 'Risk', 'Rural Population', 'Serbia'] | 20,966,203 | [['D20.693.101', 'D27.888.284.101.393'], ['N06.850.460.100'], ['Z01.542.248.160'], ['N06.850.460.350'], ['E05.320'], ['D01.362'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['E05.799'], ['D01.268.271.800', 'D01.268.613.700', 'D01.362.641.745', 'D01.496.74... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Functional shape of the skull in vertebrates: which forces determine skull morphology in lower primates and ancestral synapsids? | In order to determine the extent to which the shape of the synapsid skull is adapted for resisting the mechanical loads to which it is subjected, block- or simple plate-shaped finite-element models were constructed and loaded with external muscle and bite forces in locations estimated to resemble points of application ... | ['Animals', 'Body Patterning', 'Dogs', 'Finite Element Analysis', 'Fossils', 'Opossums', 'Primates', 'Skull', 'Species Specificity', 'Stress, Mechanical', 'Weight-Bearing'] | 15,754,317 | [['B01.050'], ['G07.345.500.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.355'], ['I01.076.368.584.311'], ['B01.050.150.900.649.573.575'], ['B01.050.150.900.649.313.988'], ['A02.835.232.781'], ['G16.824'], ['G01.374.835'], ['G01.374.965']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
The efficacy of modified luteal phase support with intramuscular progesterone in IVF/ICSI cycles: a retrospective observational study. | OBJECTIVE: The use of gonadotropin-releasing hormone agonist for ovulation triggering has become an intriguing topic in the last few years. As long as adequate luteal phase support is provided, it may be a valuable alternative to standard hCG triggering, associated with a significant reduction in OHSS incidence. Severa... | ['Adult', 'Female', 'Fertilization in Vitro', 'Gonadotropin-Releasing Hormone', 'Humans', 'Injections, Intramuscular', 'Luteal Phase', 'Ovulation Induction', 'Pregnancy', 'Pregnancy Rate', 'Progesterone', 'Retrospective Studies', 'Sperm Injections, Intracytoplasmic', 'Young Adult'] | 28,272,720 | [['M01.060.116'], ['E02.875.800.750', 'E05.820.800.750'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['G08.686.605.410'], ['E02.875.800.984', 'E05.820.800.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Surveillance and forecast for schistosome infectivity of Yangtze River and Hanbeihe River during flooding in Hubei Province]. | OBJECTIVE: To investigate the schistosome infectivity of the water body of the Yangtze River and Hanbeihe River during flooding in Hubei Province.METHODS: The Oncomelania snail status was investigated in 17 sites of the Yangtze River and Hanbei River, and the infectivity of schistosome in sentinel mice was also determi... | ['Animals', 'China', 'Environment', 'Female', 'Floods', 'Forecasting', 'Male', 'Mice', 'Population Dynamics', 'Rivers', 'Schistosomiasis', 'Sentinel Surveillance', 'Snails'] | 22,799,167 | [['B01.050'], ['Z01.252.474.164'], ['G16.500.275', 'N06.230'], ['G16.500.175.812', 'N06.230.100.230.250'], ['I01.320'], ['B01.050.150.900.649.313.992.635.505.500'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['C01.610.335.865.859', 'C01.920.922'], [... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Correlation between sex hormones and magnetic resonance imaging lesions in multiple sclerosis. | OBJECTIVE: To determine if sex hormones play a role in the pathogenesis of multiple sclerosis (MS) by correlating serum estradiol and progesterone levels with gadolinium (Gd) enhancing lesions on magnetic resonance imaging (MRI) in MS.METHODS: Thirty patients with MS were studied with Gd enhanced brain MRI and simultan... | ['Adult', 'Brain', 'Contrast Media', 'Disability Evaluation', 'Estradiol', 'Female', 'Gadolinium DTPA', 'Humans', 'Magnetic Resonance Imaging', 'Menstrual Cycle', 'Multiple Sclerosis', 'Progesterone', 'Sensitivity and Specificity'] | 10,071,166 | [['M01.060.116'], ['A08.186.211'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.400'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['G08.686.605'], ['C10.114.375.500'... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transcription by SP6 RNA polymerase exhibits an ATP dependence that is influenced by promoter topology. | Transcription of linearized DNA templates by SP6 RNA polymerase requires a higher concentration of ATP than of the other three nucleotides. This requirement is not shared by T7 RNA polymerase. The ATP requirement is partially relieved when the SP6 template is supercoiled but not when it is relaxed circular DNA. The eff... | ['Adenosine Triphosphate', 'Bacteriophage T7', 'DNA-Directed RNA Polymerases', 'Nucleic Acid Conformation', 'Promoter Regions, Genetic', 'Salmonella Phages', 'Transcription, Genetic'] | 8,493,106 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B04.123.150.700.230', 'B04.123.205.891.230', 'B04.280.090.700.230'], ['D08.811.913.696.445.735.270'], ['G02.111.570.820.486', 'G05.360.580'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['B04.123... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Tetrahydrobiopterin therapy for hyperphenylalaninemia due to phenylalanine hydroxylase deficiency. When and how?]. | INTRODUCTION: Some patients with hyperphenylalaninemia due to phenylalanine hydroxylase deficiency respond with a variable decrease in plasma phenylalanine levels after oral tetrahydrobiopterin (BH4) administration and are then able to tolerate higher dietary phenylalanine intake or even to discontinue a phenylalanine-... | ['Adolescent', 'Biopterin', 'Child', 'Child, Preschool', 'Genotype', 'Humans', 'Infant', 'Infant, Newborn', 'Nitric Oxide Synthase', 'Phenylalanine Hydroxylase', 'Phenylketonurias'] | 16,527,067 | [['M01.060.057'], ['D03.633.100.733.631.202', 'D08.211.090'], ['M01.060.406'], ['M01.060.406.448'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['D08.811.682.664.500.772'], ['D08.811.682.690.708.601'], ['C10.228.140.163.100.687', 'C16.320.565.100.766', 'C16.320.56... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum. | Excitotoxin-induced destruction of striatal neurons, proposed as a model of Huntington's disease, involves a process having the biochemical stigmata of apoptosis. Recent studies suggested that transcription factor nuclear factor (NF)-kappa B may be involved in excitotoxicity. To further analyze the contribution of NF k... | ['Animals', 'Apoptosis', 'Corpus Striatum', 'DNA', 'DNA Damage', 'NF-kappa B', 'Neurons', 'Neurotoxins', 'Nucleosomes', 'Quinolinic Acid', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, N-Methyl-D-Aspartate', 'Transcription Factors'] | 9,443,930 | [['B01.050'], ['G04.146.954.035'], ['A08.186.211.200.885.287.249.487'], ['D13.444.308'], ['G05.200'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['A08.675', 'A11.671'], ['D27.888.569.504'], ['A11.284.430.106.279.345.190.160.180.625', 'D12.776.664.224.550', 'G05.360.160.180.625'], ['D03.38... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Authentic and recombinant bilirubin oxidases are in different resting forms. | Myrothecium verrucaria bilirubin oxidase expressed in Aspergillus oryzae is in a resting form different from that of the authentic bilirubin oxidase, but reaches the resting form of the authentic enzyme after one cycle of reduction and reoxidation with dioxygen as shown by the absorption and electron paramagnetic reson... | ['Ascomycota', 'Aspergillus oryzae', 'Electron Spin Resonance Spectroscopy', 'Hydrogen-Ion Concentration', 'Oxidation-Reduction', 'Oxidoreductases Acting on CH-CH Group Donors', 'Oxygen', 'Recombinant Proteins', 'Spectrophotometry, Ultraviolet'] | 12,834,300 | [['B01.300.107'], ['B01.300.381.081.500'], ['E05.196.867.519.274'], ['G02.300'], ['G02.700', 'G03.295.531'], ['D08.811.682.660'], ['D01.268.185.550', 'D01.362.670'], ['D12.776.828'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of ischemic cerebrovascular events in cardiac embolism. | Distribution and number of ischemic cerebrovascular events were studied in 57 patients who suffered from heart disorders with proven or highly probable source of cardiac embolism and compared to 39 patients with ulcerations of the craniocervical vessels. Patients with coexisting lesions were excluded from the present s... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brain Mapping', 'Carotid Artery Thrombosis', 'Diagnostic Imaging', 'Female', 'Heart Diseases', 'Humans', 'Intracranial Embolism and Thrombosis', 'Ischemic Attack, Transient', 'Male', 'Middle Aged', 'Ophthalmic Artery', 'Thrombosis', 'Vertebrobasilar Insufficiency'] | 1,762,379 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C10.228.140.300.200.355', 'C14.907.253.123.355', 'C14.907.253.566.206', 'C14.907.355.590.213.206'], ['E01.370.350'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
WRN protects against topo I but not topo II inhibitors by preventing DNA break formation. | The Werner syndrome helicase/3'-exonuclease (WRN) is a major component of the DNA repair and replication machinery. To analyze whether WRN is involved in the repair of topoisomerase-induced DNA damage we utilized U2-OS cells, in which WRN is stably down-regulated (wrn-kd), and the corresponding wild-type cells (wrn-wt)... | ['Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Blotting, Western', 'Bone Neoplasms', 'Bromodeoxyuridine', 'Cell Cycle', 'Cell Survival', 'Colony-Forming Units Assay', 'DNA Breaks', 'DNA Repair', 'DNA Topoisomerases, Type I', 'DNA Topoisomerases, Type II', 'Enzyme Inhibitors', 'Etoposide', 'Exodeoxyribonucleases', ... | 18,805,512 | [['D27.505.954.248.179'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.149', 'C05.116.231'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G04.144'], ['G04.346'], ['E01.370.225.500.383', 'E05.20... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Discrepancies between two alternative staging systems (European Neuroendocrine Tumor Society 2006 and American Joint Committee on Cancer/Union for International Cancer Control 2010) of neuroendocrine neoplasms of the pancreas. A study of 50 cases. | The aim of our study was to identify and describe potential inconsistencies between two alternative staging systems of pancreatic neuroendocrine neoplasms (pNENs)--the European Neuroendocrine Tumor Society (ENETS) system (2006) and the American Joint Committee on Cancer/Union for International Cancer Control (AJCC-UICC... | ['Adult', 'Aged', 'Carcinoma, Neuroendocrine', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Neuroendocrine Tumors', 'Organizations', 'Pancreatic Neoplasms', 'Prognosis', 'Retrospective Studies', 'Young Adult'] | 21,354,717 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.465.625.650.240', 'C04.557.470.200.025.370', 'C04.557.580.625.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['C04.557.465.625.650', 'C04.557.580.625.650'], ['N03.540'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.76... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Idiopathic pulmonary haemosiderosis: report of two cases and review of the literature. | Idiopathic pulmonary haemosiderosis (IPH) is a rare disorder affecting mainly children and adolescents, and is usually fatal. However, there is increasing evidence that the aetiology of this condition is immunological, and that immunosuppressives may prolong remission. Two cases are reported, one of which has the atypi... | ['Anemia, Hypochromic', 'Child', 'Female', 'Hemosiderosis', 'Humans', 'Lung Diseases', 'Malabsorption Syndromes', 'Male'] | 471,863 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The majority of stem cell factor exists as monomer under physiological conditions. Implications for dimerization mediating biological activity. | Soluble Escherichia coli-derived recombinant human stem cell factor (rhSCF) forms a non-covalently associated dimer. We have determined a dimer association constant (Ka) of 2-4 x 10(8) M-1, using sedimentation equilibrium and size exclusion chromatography. SCF has been shown previously to be present at concentrations o... | ['Amino Acid Sequence', 'Chromatography, Gel', 'Circular Dichroism', 'Humans', 'Models, Biological', 'Molecular Sequence Data', 'Protein Binding', 'Proto-Oncogene Proteins c-kit', 'Recombinant Proteins', 'Solubility', 'Spectrometry, Fluorescence', 'Stem Cell Factor', 'Ultracentrifugation'] | 9,045,664 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.181.400.250'], ['E05.196.867.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['L01.453.245.667'], ['G02.111.679', 'G03.808'], ['D08.811.913.696.620.682.725.400.050', 'D12.776.543.750.630.124', 'D12.776.543.750.705.852.150.100', 'D12.776.543... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of site of administration in the gastrointestinal tract on the absorption of insulin from nanocapsules in diabetic rats. | Isobutylcyanoacrylate nanocapsules have been used as drug carriers for the enteral absorption of insulin. Their absorption has been studied by measuring fasted glycaemia in streptozotocin-induced diabetic rats after a single administration of encapsulated insulin (100 units kg-1) at various sites along the gastrointest... | ['Animals', 'Capsules', 'Diabetes Mellitus, Experimental', 'Drug Carriers', 'Emulsions', 'Gastric Mucosa', 'Insulin', 'Intestinal Absorption', 'Intestinal Mucosa', 'Male', 'Rats', 'Rats, Inbred Strains'] | 1,676,051 | [['B01.050'], ['D26.255.150'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D26.255.260', 'E02.319.300.380'], ['D20.280.260', 'D26.255.165.260'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.015.500.374.500', 'G03.787.024.500.374.500',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of physical exam signs for early detection of critical illness in pediatric systemic inflammatory response syndrome. | BACKGROUND: Early detection of compensated pediatric septic shock requires diagnostic tests that are sensitive and specific. Four physical exam signs are recommended for detecting pediatric septic shock prior to hypotension (cold extremities, mental status, capillary refill, peripheral pulse quality); this study tested... | ['Adolescent', 'Child', 'Child, Preschool', 'Critical Illness', 'Early Diagnosis', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Logistic Models', 'Male', 'Multiple Organ Failure', 'Physical Examination', 'Prospective Studies', 'Sensitivity and Specificity', 'Shock, Septic', 'Systemic Inflammatory Response Syndrome... | 25,407,007 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.625'], ['E01.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.70... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Risk factors associated with methicillin-resistant Staphylococcus aureus colonization on hospital admission among oncology patients. | A nested case-control study at a tertiary care facility was conducted to assess potential risk factors for colonization with methicillin-resistant Staphylococcus aureus (MRSA) on admission among oncology patients. Risk factors for any S aureus and MRSA colonization on admission in oncology patients are consistent with ... | ['Antineoplastic Agents', 'Carrier State', 'Case-Control Studies', 'Cross Infection', 'Female', 'Hospitalization', 'Humans', 'Immunocompromised Host', 'Infection Control', 'Male', 'Methicillin-Resistant Staphylococcus aureus', 'Middle Aged', 'Nose', 'Odds Ratio', 'Oncology Service, Hospital', 'Patient Admission', 'Retr... | 19,362,391 | [['D27.505.954.248'], ['N06.850.520.169'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.248', 'C23.550.291.875.500'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'], ['N06.850.780.200.450'], ['B03.300.390.400.800.750.100.500', 'B0... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The social recognition of human dignity. | This paper argues that the notion of human dignity has to do with a social status, whose recognition and respect are owed by society. Therefore, those who violate human dignity violate a social reality. This means that human dignity does not need any philosophical or theological foundation. Instead, it can be understan... | ['Humans', 'Personhood', 'Social Desirability', 'Social Identification'] | 21,452,607 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.752.566.479.660', 'N05.350.917'], ['F01.145.813.628'], ['F01.145.813.708']] | ['Organisms [B]', 'Humanities [K]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Slow dynamics and high variability in balanced cortical networks with clustered connections. | Anatomical studies demonstrate that excitatory connections in cortex are not uniformly distributed across a network but instead exhibit clustering into groups of highly connected neurons. The implications of clustering for cortical activity are unclear. We studied the effect of clustered excitatory connections on the d... | ['Action Potentials', 'Animals', 'Cerebral Cortex', 'Cluster Analysis', 'Computer Simulation', 'Humans', 'Models, Neurological', 'Nerve Net', 'Neurons', 'Nonlinear Dynamics'] | 23,001,062 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.642'], ['A08.511'], ['A08.675', 'A11.671'], ['E05.599.850', 'H01.548.67... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of selective serotonin reuptake inhibitors on intraocular pressure and anterior segment parameters in open angle eyes. | PURPOSE: To evaluate the short- and long-term effects of selective serotonin reuptake inhibitors (SSRIs) on intraocular pressure (IOP) and anterior segment parameters in open angle eyes.MATERIALS AND METHODS: This cross-sectional study included 325 eyes of 166 subjects. Subjects were divided into three groups: Group 1 ... | ['Adolescent', 'Adult', 'Anterior Eye Segment', 'Depressive Disorder, Major', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Mydriasis', 'Serotonin Uptake Inhibitors', 'Young Adult'] | 28,504,010 | [['M01.060.057'], ['M01.060.116'], ['A09.371.060'], ['F03.600.300.375'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['M01.060.116.630'], ['C11.710.570'], ['D27.505.519.562.437.850', 'D27.505.519.625.600.850', 'D27.505.519.625.850.900', 'D27.505.696.577.600.850', 'D27.505.696.577.... | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gap junctions and fluid flow response in MC3T3-E1 cells. | In the current study, we examined the role of gap junctions in oscillatory fluid flow-induced changes in intracellular Ca(2+) concentration and prostaglandin release in osteoblastic cells. This work was completed in MC3T3-E1 cells with intact gap junctional communication as well as in MC3T3-E1 cells rendered communicat... | ['Animals', 'Calcium', 'Calcium Signaling', 'Cell Communication', 'Cell Line', 'Dinoprostone', 'Enzyme Inhibitors', 'Gap Junctions', 'Microscopy, Fluorescence', 'Osteoblasts', 'Pulsatile Flow', 'Stress, Mechanical', 'Thapsigargin', 'Time Factors'] | 11,698,250 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['G04.085'], ['A11.251.210'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D27.505.519.389'], ['A11.284.149.165.420.471'], ['E01.370.350.515.458', 'E05.595.458'], ['A1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mandibular pseudocarcinomatous hyperplasia. | AIMS: Three unusual cases of pseudocarcinomatous (pseudoepitheliomatous) hyperplasia (PH) affecting chronic osteomyelitic mandibular sequestra are reported to highlight the differences with the various squamous neoplasms which occur in that site.METHODS AND RESULTS: In two patients carrying a mandibular graft following... | ['Adolescent', 'Adult', 'Carcinoma, Squamous Cell', 'Diagnosis, Differential', 'Epithelial Cells', 'Female', 'Humans', 'Hyperplasia', 'Male', 'Mandible', 'Mouth Neoplasms'] | 10,931,233 | [['M01.060.057'], ['M01.060.116'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.171'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['C04.588.443.591', 'C07.465.530']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Calorie restriction attenuates inflammatory responses to myocardial ischemia-reperfusion injury. | The life-prolonging effects of calorie restriction (CR) may be due to reduced damage from cumulative oxidative stress. Our goal was to determine the long-term effects of moderate dietary CR on the myocardial response to reperfusion after a single episode of sublethal ischemia. Male Fisher 344 rats were fed either an ad... | ['Animals', 'Catalase', 'DNA-Binding Proteins', 'Energy Intake', 'Energy Metabolism', 'Free Radicals', 'Gene Expression Regulation, Enzymologic', 'Glutathione', 'Glutathione Disulfide', 'Glutathione Peroxidase', 'Interleukin-1', 'Interleukin-6', 'Male', 'Myocardial Reperfusion Injury', 'NF-kappa B', 'Oxidative Stress',... | 11,299,211 | [['B01.050'], ['D08.811.682.732.332'], ['D12.776.260'], ['G07.203.650.240.340'], ['G03.295'], ['D01.339', 'D02.389'], ['G05.308.320'], ['D12.644.456.448'], ['D12.644.456.448.500'], ['D08.811.682.732.500'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrastructural distribution of von Willebrand factor in human glomerular diseases. | The distribution of the von Willebrand factor (vWF) as the factor-VIII-related antigen in glomeruli was examined by immunoelectron microscopy in 10 patients with idiopathic membranous nephropathy (MN), 8 patients with minimal-change nephrotic syndrome (MCNS), and 11 patients with IgA nephropathy (IgA-N). Electron-dense... | ['Glomerulonephritis, IGA', 'Glomerulonephritis, Membranous', 'Humans', 'Immunoglobulin A', 'Immunologic Techniques', 'Microscopy, Electron', 'Nephrotic Syndrome', 'von Willebrand Factor'] | 2,689,898 | [['C12.777.419.570.363.608', 'C13.351.968.419.570.363.608', 'C20.111.525'], ['C12.777.419.570.363.625', 'C13.351.968.419.570.363.625', 'C20.111.535'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['E05.478'], ... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developing a framework for understanding and enabling open source drug discovery. | Open source drug discovery is increasingly being sought as a solution for managing product development complexities. Three drivers encouraging the use of the open source strategy include: upstream knowledge-based complexities associated with complementary assets, technological complexities given the scale of research a... | ['Commerce', 'Cooperative Behavior', 'Drug Design', 'Drug Discovery', 'Drug Industry', 'Research Design'] | 22,827,795 | [['J01.219'], ['F01.145.813.115'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['J01.576.655.750'], ['E05.581.500', 'H01.770.644.728']] | ['Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Frequencies and mechanisms of resistance to moxifloxacin in nosocomial isolates of Acinetobacter baumannii. | OBJECTIVES: To compare the in vitro activity of moxifloxacin and ciprofloxacin against 226 nosocomial isolates of Acinetobacter baumannii from 44 hospitals in the UK.METHODS: MICs of ciprofloxacin and moxifloxacin were determined by Etest. PCR analysis was used to detect chromosomal mutations in the gyrA and parC genes... | ['Acinetobacter Infections', 'Acinetobacter baumannii', 'Aza Compounds', 'Cross Infection', 'Dose-Response Relationship, Drug', 'Drug Resistance, Bacterial', 'Fluoroquinolones', 'Humans', 'Microbial Sensitivity Tests', 'Moxifloxacin', 'Quinolines'] | 12,951,327 | [['C01.150.252.400.560.022'], ['B03.440.400.425.537.050.099', 'B03.660.250.530.050.099'], ['D02.145'], ['C01.248', 'C23.550.291.875.500'], ['G07.690.773.875', 'G07.690.936.500'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['D03.633.100.810.835.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of the antituberculous agent ethambutol on myelinated nerve. | The action of the antituberculous agent ethambutol on the myelinated nerve was studied in two ways: (1) Resting and compound action potentials of the desheathed sciatic nerve were measured; (2) Na+ and K+ currents through the node of Ranvier were investigated by means of the voltage clamp. Reversible dose-dependent dec... | ['Action Potentials', 'Animals', 'Anura', 'Calcium', 'Ethambutol', 'In Vitro Techniques', 'Membrane Potentials', 'Nerve Fibers, Myelinated', 'Potassium', 'Rana esculenta', "Ranvier's Nodes", 'Sciatic Nerve', 'Sodium'] | 308,884 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['B01.050.150.900.090.180'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.092.782.258.368.265'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.514'], ['D01.268.54... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Time-resolved fluoroimmunoassay for unconjugated estrogen in urine: comparison with a fluorometric assay for total estrogen and application in an in vitro fertilization program. | A time-resolved fluoroimmunoassay (TR-FIA) for unconjugated estrogens in human urine is described. 6-Keto-17 beta-estradiol-6-(O-carboxymethyl)oxime:bovine serum albumin is immobilized onto microtiter strip wells and the coated wells are incubated with 17 beta-estradiol standard preparations or unknowns with a polyclon... | ['Autoanalysis', 'Estrogens', 'Female', 'Fertilization in Vitro', 'Fluoroimmunoassay', 'Fluorometry', 'Follicular Phase', 'Humans', 'Ovulation Induction'] | 2,208,653 | [['E05.059'], ['D27.505.696.399.472.277'], ['E02.875.800.750', 'E05.820.800.750'], ['E01.370.225.500.607.512.240.655', 'E01.370.225.750.551.512.240.655', 'E05.200.500.607.512.240.655', 'E05.200.750.551.512.240.655', 'E05.478.566.159', 'E05.478.583.375.655'], ['E05.196.712.516.600'], ['G08.686.605.310'], ['B01.050.150.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recombinant Adenovirus Expressing a Soluble Fusion Protein PD-1/CD137L Subverts the Suppression of CD8+ | Oncolytic viruses are an excellent platform for developing effective strategies in cancer immunotherapy. Several challenges remain in the use of viro-immunotherapy for cancer, such as the lack of costimulatory signals and negative regulation of immune checkpoints. In this study, we designed a novel adenovirus expressin... | ['4-1BB Ligand', 'Adenoviridae', 'Animals', 'CD8-Positive T-Lymphocytes', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Disease Models, Animal', 'Gene Expression', 'Genetic Therapy', 'Genetic Vectors', 'Humans', 'Immunomodulation', 'Liver Neoplasms', 'Lymphocyte Activation', 'Mice', 'Oncolytic Virotherapy', 'Oncoly... | 31,466,933 | [['D12.644.276.374.750.065', 'D12.776.395.192', 'D12.776.467.374.750.065', 'D12.776.543.550.194', 'D23.529.374.750.065'], ['B04.280.030'], ['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Predicting who benefits from psychoeducation and self help for panic attacks. | UNLABELLED: Self-help and psychoeducation have been identified as effective methods for delivering treatment, yet not everyone benefits from these brief interventions. Therefore it is clinically and economically useful to identify who is likely to require more intensive assistance. This paper develops a prognostic scal... | ['Adult', 'Female', 'Humans', 'Male', 'Middle Aged', 'Panic Disorder', 'Patient Education as Topic', 'Patient Selection', 'Prognosis', 'Psychotherapy, Brief', 'Regression Analysis', 'Self Care', 'Treatment Outcome'] | 15,033,498 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.080.700'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E05.581.500.653', 'N04.590.731'], ['E01.789'], ['F04.754.738'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E02.900', 'I03.050.563', 'N02.421.78... | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Digital radiography and electronic data storage from the perspective of legal requirements for record keeping. | In some countries physicians and dentists are required by law to keep medical and dental records. These records not only serve as personal notes and memory aids but have to be in accordance with the necessary standard of care and may be used as evidence in litigation. Inadequate, incomplete or even missing records can ... | ['Computer Security', 'Confidentiality', 'Forensic Medicine', 'Forms and Records Control', 'Germany', 'Humans', 'Information Storage and Retrieval', 'Legislation, Medical', 'Medical Records Systems, Computerized', 'Radiographic Image Enhancement'] | 14,686,680 | [['L01.224.134', 'N04.452.910.200'], ['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['H02.403.330', 'I01.198.780.937'], ['N04.452.758.708.200.400'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'],... | ['Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
[Multiorgan damage in exertion heatstroke]. | The paper reports a fatal case of exertion heat stroke. The etiopathogenetic, clinical and therapeutic aspects of the case are described; although rarely observed, this pathology must be taken into account by the intensive care unit in order to ensure rapid aid and treatment in an attempt to modify the severe prognosis... | ['Adult', 'Heat Exhaustion', 'Humans', 'Male', 'Multiple Organ Failure'] | 1,508,348 | [['M01.060.116'], ['C26.522.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.835.525']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic engineering with endothelial nitric oxide synthase improves functional properties of endothelial progenitor cells from patients with coronary artery disease: an in vitro study. | Recent studies have reported a marked impairment in the number and functions of endothelial progenitor cells (EPCs) in patients with coronary artery disease (CAD). In view of an important role of eNOS in angiogenesis, in the present study, we evaluated the effects of eNOS gene transfer in ex vivo expanded EPCs isolated... | ['Adult', 'Aged', 'Cell Differentiation', 'Cells, Cultured', 'Coronary Artery Disease', 'Endothelial Cells', 'Female', 'Flow Cytometry', 'Gene Transfer Techniques', 'Genetic Therapy', 'Humans', 'Immunohistochemistry', 'In Vitro Techniques', 'Male', 'Middle Aged', 'Neovascularization, Physiologic', 'Nitric Oxide Synthas... | 19,479,297 | [['M01.060.116'], ['M01.060.116.100'], ['G04.152'], ['A11.251'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A11.436.275'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Moving research beyond the spanking debate. | Despite numerous studies identifying a broad range of harms associated with the use of spanking and other types of physical punishment, debate continues about its use as a form of discipline. In this commentary, we recommend four strategies to move the field forward and beyond the spanking debate including: 1) use of m... | ['Aggression', 'Child', 'Child Advocacy', 'Child Rearing', 'Child, Preschool', 'Cross-Cultural Comparison', 'Cross-Sectional Studies', 'Forecasting', 'Humans', 'Infant', 'Ontario', 'Physical Abuse', 'Punishment', 'Research', 'Social Values'] | 28,249,733 | [['F01.145.126.125', 'F01.145.813.045'], ['M01.060.406'], ['I01.880.604.473.300', 'I01.880.787.293.350', 'N03.706.437.300'], ['F01.318'], ['M01.060.406.448'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.320'], ['B01.050.150.900.649... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Adaptive latitudinal cline of photoperiodic diapause induction in the parasitoid Nasonia vitripennis in Europe. | Living in seasonally changing environments requires adaptation to seasonal cycles. Many insects use the change in day length as a reliable cue for upcoming winter and respond to shortened photoperiod through diapause. In this study, we report the clinal variation in photoperiodic diapause induction in populations of th... | ['Adaptation, Biological', 'Animals', 'Europe', 'Female', 'Genetic Variation', 'Genetics, Population', 'Genome, Insect', 'Geography', 'Larva', 'Microsatellite Repeats', 'Photoperiod', 'Population Dynamics', 'Seasons', 'Selection, Genetic', 'Temperature', 'Time Factors', 'Wasps'] | 23,496,837 | [['G16.012'], ['B01.050'], ['Z01.542'], ['G05.365'], ['H01.158.273.343.335'], ['G05.360.340.357'], ['H01.277.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['G01.910.675'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Comparison of nitrazepam and zopiclone in psychiatric patients. | This investigation compares the effects of single and double doses of nitrazepam (5 and 10 mg) and zopiclone (7.5 and 15 mg) and placebo for 1 night in 40 psychiatric patients. The results indicate that zopiclone is an active hypnotic compound, comparable in its effects to those of nitrazepam, the higher dosage being b... | ['Adolescent', 'Adult', 'Aged', 'Azabicyclo Compounds', 'Clinical Trials as Topic', 'Double-Blind Method', 'Emotions', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Male', 'Memory', 'Mental Disorders', 'Middle Aged', 'Nitrazepam', 'Piperazines', 'Random Allocation', 'Sleep Wake Disorders', 'Surveys and Questionnaires... | 6,765,245 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D02.145.074', 'D03.605.084.500'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development and field testing of Teen Pocket PATH(®), a mobile health application to improve medication adherence in adolescent solid organ recipients. | Applying principles of user-centered design, we iteratively developed and tested the prototype of TPP, an mHealth application to promote medication adherence and enhance communication about medication management between adolescents and primary caregivers. A purposive sample of seven adolescent solid organ transplant re... | ['Adolescent', 'Adolescent Medicine', 'Adult', 'Caregivers', 'Child', 'Female', 'Health Promotion', 'Humans', 'Immunosuppressive Agents', 'Male', 'Medication Adherence', 'Middle Aged', 'Organ Transplantation', 'Patient Satisfaction', 'Reminder Systems', 'Self Care', 'Surveys and Questionnaires', 'Telemedicine', 'Text M... | 26,916,967 | [['M01.060.057'], ['H02.403.014'], ['M01.060.116'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['F01.100.150.750.500.600.500', 'F01.145.488.887.500.600.500', 'N05.300.150.800.500.60... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Sorption of small metabolites of nonylphenol polyethoxylates in single and complex systems on aquatic suspended particulate matter. | Sorption of nonylphenol (NP), nonylphenol monoethoxylate (NP1EO) and nonylphenol diethoxylate (NP2EO) as well as their binary and ternary mixtures were studied and compared on three simulated suspended particulate matters (SPMs). Sorption dynamics of NP on the three SPMs could be divided into two phases, the rapid sorp... | ['Adsorption', 'Biodegradation, Environmental', 'Hydrogen-Ion Concentration', 'Micelles', 'Nonoxynol', 'Particle Size', 'Surface-Active Agents', 'Temperature', 'Time Factors', 'Water Pollutants, Chemical'] | 16,213,551 | [['G01.030', 'G02.020'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G02.300'], ['D05.374', 'D26.255.560'], ['D02.033.455.250.700.620', 'D05.750.741.575', 'D25.720.741.575', 'J01.637.051.720.741.575'], ['G02.712'], ['D27.720.877'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Enhancing behavioral change among lung cancer survivors participating in a lifestyle risk reduction intervention: a qualitative study. | PURPOSE: Early detection and improved treatment have increased lung cancer survival. Lung cancer survivors have more symptom distress and lower function compared with other cancer survivors; however, few interventions are available to improve health-related quality of life (HR-QOL). Lifestyle risk reduction interventio... | ['Adult', 'Aged', 'Cancer Survivors', 'Exercise', 'Feasibility Studies', 'Female', 'Health Behavior', 'Humans', 'Interviews as Topic', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Motivation', 'Patient Acceptance of Health Care', 'Patient Education as Topic', 'Quality of Life', 'Risk Reduction Behavior', 'Secondary Preven... | 30,643,990 | [['M01.060.116'], ['M01.060.116.100'], ['M01.860.350'], ['G11.427.410.698.277', 'I03.350'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.4... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Association of aciculin with dystrophin and utrophin. | Aciculin is a recently identified 60-kDa cytoskeletal protein, highly homologous to the glycolytic enzyme phosphoglucomutase type 1, (Belkin, A. M., Klimanskaya, I. V., Lukashev, M. E., Lilley, K., Critchley, D., and Koteliansky, V. E. (1994) J. Cell Sci. 107, 159-173). Aciculin expression in skeletal muscle is develop... | ['Animals', 'Cell Differentiation', 'Cell Line', 'Cell Membrane', 'Chickens', 'Chromatography, Affinity', 'Chromatography, Gel', 'Cysteine', 'Cytoskeletal Proteins', 'Dystrophin', 'Electrophoresis, Polyacrylamide Gel', 'Gizzard, Avian', 'Membrane Proteins', 'Methionine', 'Mice', 'Molecular Weight', 'Muscle, Skeletal', ... | 7,890,770 | [['B01.050'], ['G04.152'], ['A11.251.210'], ['A11.284.149'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.170'], ['E05.196.181.400.250'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D12.776.220'], ['D12.776.210.500.250', 'D12.776.220.250', 'D12.77... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of selected trace elements in foodstuffs and biological materials by destructive neutron activation analysis. | Concentration of trace elements in Nescaf?, Fariman sugar, and Sadaf turmeric and mercury content in cancerous blood were determined by radiochemical, neutron activation analysis. By this separation method levels of 110mAg, 198Au, 203Hg, 76Se, 51Cr, 24Na, 42K, 99Mo, 122Sb, 82Br, 59Fe, 60Co were measured without interfe... | ['Food Analysis', 'Neutron Activation Analysis', 'Trace Elements'] | 8,748,216 | [['E05.362', 'J01.576.423.850.100'], ['E05.196.039.564'], ['D01.268.811', 'D27.505.696.494.555', 'G07.203.300.681.500.555', 'J02.500.681.500.555']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Efficiency of various vitamin doses for polyhypovitaminosis correction in rats. | A 5-fold decrease of the content of vitamin mixture in the ration and exclusion of vitamin E from this mixture over 4 weeks led to a significant growth delay in rats initially weighing 58.1±0.5 g, but was inessential for the growth rates of animals weighing 107.1±1.1 g. The decrease in the levels of vitamins A and B2 i... | ['Animals', 'Avitaminosis', 'Dose-Response Relationship, Drug', 'Male', 'Rats', 'Rats, Wistar', 'Vitamins'] | 25,257,423 | [['B01.050'], ['C18.654.521.500.133'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D27.505.696.494.600', 'G07.203.300.681.500.600', 'J02.500.681.500.600']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Mediastinal lymph nodes micro-metastases in patients with clinical stage I-II lung cancer]. | OBJECTIVE: To investigate micro-metastasis in mediastinal lymph nodes (mLN) of patients with clinical stage I approximately II lung cancer and its clinical significance.METHODS: A total of 181 mLN from 32 lung cancer patients in clinical stage I approximately II were collected during operation and their frozen sections... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antibodies, Monoclonal', 'Carcinoma, Squamous Cell', 'Female', 'Humans', 'Lung Neoplasms', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Mediastinum', 'Middle Aged', 'Neoplasm Staging'] | 15,946,566 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['A10.549... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association between preconceptional treatment with insulin pumps and improved metabolic status in early pregnancy in women with type 1 diabetes. | INTRODUCTION: An adverse intrauterine environment in early pregnancy in women with type 1 diabetes is associated with several perinatal complications including spontaneous abortions, fetal congenital defects, and preeclampsia.OBJECTIVES: We compared metabolic parameters in the first trimester of pregnancy between women... | ['Adult', 'Cross-Sectional Studies', 'Diabetes Complications', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Hypoglycemic Agents', 'Infusions, Subcutaneous', 'Insulin Infusion Systems', 'Insulin, Long-Acting', 'Pregnancy', 'Pregnancy Trimester, First', 'Pregnancy in Diabetics', 'Young Adult'] | 25,827,639 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C19.246.099'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['E02.319.267.510.795'], ['E02.319.300.508', 'E07.505.508', 'E07.858.082.505.508'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Electrophysiological evidence for the effects of emotional content on false recognition memory. | Two competing hypotheses attempt to explain the effects of emotional content on the production of false memory. The conceptual relatedness account posits that negative emotion increases false memory by strengthening familiarity process, whereas the distinctiveness heuristic account postulates that negative emotion redu... | ['Adult', 'Brain', 'Electroencephalography', 'Emotions', 'Evoked Potentials', 'Female', 'Heuristics', 'Humans', 'Male', 'Mental Recall', 'Recognition, Psychology', 'Young Adult'] | 30,064,656 | [['M01.060.116'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['F01.470'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.463.425.725.500', 'F02.463.785.810.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.425.540.706'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Admissions procedures of educational programs for the specialist in blood bank technology. | A national survey of specialists in blood bank technology educational programs was performed to describe current admissions procedures. Programs generally were AABB approved for and accepted either two or four students annually from 10 to 14 complete applications which result from 25 to 50 inquiries. The program select... | ['Blood Banks', 'Humans', 'Medical Laboratory Science', 'Surveys and Questionnaires', 'United States'] | 7,292,586 | [['N02.278.065.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.010.450', 'J01.897.480'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.107.567.875']] | ['Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Metastases to the parotid nodes: CT and MR imaging findings. | OBJECTIVES: To present and characterize CT and MR imaging findings of metastases to the parotid nodes.METHODS: CT (n = 10) and MR (n = 11) images from 14 patients with metastases to the parotid nodes were reviewed. The primary tumour sites were the ocular adnexa in five patients, facial skin in four patients, upper aer... | ['Aged', 'Aged, 80 and over', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Parotid Neoplasms', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 27,635,667 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.588.443.591.824.695', 'C07.465.530.824.695', 'C07.465.815.470.770', 'C07.465.815.718.589'], ['E05.318.372.500.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metabolism of some naturally occurring isothiocyanates in the rat. | The metabolism of methyl, ethyl, butyl and allyl isothiocyanate, which occur as glucosinolates in a number of plants, was studied. Oral administration of the substances to the rat was followed by their renal excretion as mercapturic acids, which were isolated as dicyclohexylamine salts. Chemical structure was determine... | ['Acetylcysteine', 'Animals', 'Isothiocyanates', 'Male', 'Rats', 'Rats, Inbred Strains', 'Thiocarbamates', 'Thiocyanates'] | 6,624,135 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['B01.050'], ['D02.500.375', 'D02.886.250'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D02.241.081.251.869', 'D02.886.706'], ['D02.262.775', 'D02.886.728']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accurate epileptogenic focus localization through time-variant functional connectivity analysis of intracranial electroencephalographic signals. | Epilepsy is a neurological disorder characterized by seizures, i.e. abnormal synchronous activity of neurons in the brain. During a focal seizure, the abnormal synchronous activity starts in a specific brain region and rapidly propagates to neighboring regions. Intracranial ElectroEncephaloGraphy (IEEG) is the recordin... | ['Algorithms', 'Causality', 'Drug Resistance', 'Electrodes', 'Electroencephalography', 'Epilepsy', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Models, Statistical', 'Multivariate Analysis', 'Regression Analysis', 'Seizures', 'Signal Processing, Computer-Assisted', 'Tomography, X-Ray ... | 21,316,472 | [['G17.035', 'L01.224.050'], ['N05.715.350.200', 'N06.850.490.625'], ['G07.690.773.984'], ['E07.305.250'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Imprecision of tumour biomarker measurements on Roche Modular E170 platform fulfills desirable goals derived from biological variation. | BACKGROUND: Monitoring of test imprecision is one of the most important quality indicators in clinical laboratories. Imprecision goals should be derived from biological variation. The aim of this study was to evaluate the imprecision of eight tumour biomarker assays routinely measured on the Modular E170 system.METHODS... | ['Antigens, Neoplasm', 'Biomarkers, Tumor', 'CA-19-9 Antigen', 'Carcinoembryonic Antigen', 'Clinical Laboratory Techniques', 'Data Collection', 'Ferritins', 'Humans', 'Keratin-19', 'Male', 'Prostate-Specific Antigen', 'Time Factors', 'alpha-Fetoproteins'] | 20,144,978 | [['D23.050.285'], ['D23.101.140'], ['D23.050.285.050.119', 'D23.050.301.290.544.119', 'D23.050.550.325.119', 'D23.050.705.230.544.119', 'D23.101.140.075.119'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['E01.370.225', 'E05.200'], ['E05.318.308',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Liver type fatty acid binding protein (L-FABP) gene ablation reduces nuclear ligand distribution and peroxisome proliferator-activated receptor-alpha activity in cultured primary hepatocytes. | The effect of liver type fatty acid binding protein (L-FABP) gene ablation on the uptake and distribution of long chain fatty acids (LCFA) to the nucleus by real-time laser scanning confocal imaging and peroxisome proliferator-activated receptor-alpha (PPARalpha) activity was examined in cultured primary hepatocytes fr... | ['Animals', 'COS Cells', 'Cells, Cultured', 'Chlorocebus aethiops', 'Fatty Acid-Binding Proteins', 'Hepatocytes', 'Immunoprecipitation', 'Ligands', 'Male', 'Mice', 'Mice, Knockout', 'Microscopy, Confocal', 'PPAR alpha'] | 19,285,478 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D12.776.157.170'], ['A11.436.348'], ['E05.196.150.639', 'E05.478.605'], ['D27.720.470.480'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of safflor yellow B on vascular endothelial cells injury induced by angiotensin-II]. | This study is to investigate protective effect of safflor yellow B (SYB) against vascular endothelial cells (VECs) injury induced by angiotensin-II (Ang-II). VECs were cultured and divided into six groups: control group, Ang-II group, Ang-II + SYB (1 micromolL(-1)) group, Ang-II + SYB (10 micromolL(-1)) group, Ang-II +... | ['Angiotensin II', 'Antioxidants', 'Apoptosis', 'Calcium', 'Carthamus tinctorius', 'Caspase 3', 'Cells, Cultured', 'Chalcone', 'Drugs, Chinese Herbal', 'Electron Transport Complex IV', 'Endothelial Cells', 'Humans', 'Membrane Potential, Mitochondrial', 'Mitochondrial Proton-Translocating ATPases', 'Plants, Medicinal', ... | 22,919,732 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.650.940.800.575.912.250.100.18... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of ivermectin treatment against inhibited early third stage, late third stage and fourth stage larvae and adult stages of the cyathostomes in Shetland ponies and spontaneous expulsion of these helminths. | A controlled and critical test on the efficacy of ivermectin against larval and adult stages of the cyathostomes was carried out in six yearling castrated male Shetland ponies. The ponies grazed together as one group from 3 May to 4 October 1990, after which they were housed. Three ponies were treated with ivermectin o... | ['Animals', 'Feces', 'Horses', 'Ivermectin', 'Larva', 'Male', 'Parasite Egg Count', 'Strongyle Infections, Equine', 'Strongyloidea'] | 1,496,789 | [['B01.050'], ['A12.459'], ['B01.050.150.900.649.313.984.235.472'], ['D02.540.576.500.997'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E01.370.225.932.600', 'E05.200.932.600'], ['C01.610.335.349.840', 'C01.610.335.508.700.775.773', 'C01.610.701.377.840', 'C22.488.861', 'C22.674.377.840'], ['B01.050.500.500.294.400.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Length adaptation of airway smooth muscle: a stochastic model of cytoskeletal dynamics. | To account for cytoskeleton remodeling as well as smooth muscle length adaptation, here we represent the cytoskeleton as a two-dimensional network of links (contractile filaments or stress fibers) that connect nodes (dense plaques or focal adhesions). The network evolves in continuous turnover with probabilities of lin... | ['Adaptation, Physiological', 'Animals', 'Computer Simulation', 'Cytoskeleton', 'Elasticity', 'Humans', 'Lung', 'Mechanotransduction, Cellular', 'Models, Biological', 'Models, Statistical', 'Muscle Contraction', 'Muscle, Smooth', 'Stochastic Processes', 'Stress, Mechanical', 'Trachea'] | 16,081,628 | [['G07.025', 'G16.012.500'], ['B01.050'], ['L01.224.160'], ['A11.284.430.214.190.750'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['G01.154.090.500', 'G02.111.820.580', 'G04.835.580'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'],... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Cytokine serum levels in patients with chronic HCV infection. | The pathogenic role of immune-mediated mechanisms in chronic hepatitis C virus (HCV) infection has not yet been elucidated. In this study, we report different cytokine expression profiles from hemodialysis (HD) and non-HD HCV (+) patients. IL-1beta, IL-2, IL-4, IL-6, TNF-alpha, and TGF-beta1 serum levels, and liver bio... | ['Adult', 'Antibodies, Viral', 'Case-Control Studies', 'Cytokines', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Liver', 'Male', 'Middle Aged', 'Transforming Growth Factor beta'] | 11,835,530 | [['M01.060.116'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of inspiratory muscle training in older adults. | PURPOSE: Declining inspiratory muscle function and structure and systemic low-level inflammation and oxidative stress may contribute to morbidity and mortality during normal ageing. Therefore, we examined the effects of inspiratory muscle training (IMT) in older adults on inspiratory muscle function and structure and s... | ['Accelerometry', 'Adipose Tissue', 'Aged', 'Breathing Exercises', 'Cytokines', 'DNA Damage', 'Exercise Tolerance', 'Humans', 'Leukocytes, Mononuclear', 'Motor Activity', 'Mouth', 'Muscle Strength', 'Oxidative Stress', 'Physical Endurance', 'Pressure', 'Quality of Life', 'Respiratory Muscles', 'Spirometry', 'Work of Br... | 25,116,085 | [['E05.003'], ['A10.165.114'], ['M01.060.116.100'], ['E02.190.525.186', 'E02.779.474.124'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.200'], ['G11.427.680.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['F01.145.632', 'G11.427.41... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Structure, diffusion, and permeability of protein-stabilized monodispersed oil in water emulsions and their gels: a self-diffusion NMR study. | Self-diffusion NMR is used to investigate monodispersed oil in water emulsions and the subsequent gel formed by removing the water through evaporation. The radius of the oil droplets in the emulsions is measured using a number of diffusion methods based on the measurement of the mean squared displacement of the oil, wa... | ['Diffusion', 'Emulsions', 'Gels', 'Lactoglobulins', 'Magnetic Resonance Spectroscopy', 'Microfluidics', 'Microscopy', 'Oils', 'Particle Size', 'Permeability', 'Porosity', 'Proteins', 'Time Factors', 'Water'] | 20,369,894 | [['G01.202', 'G02.196'], ['D20.280.260', 'D26.255.165.260'], ['D20.280.320', 'D26.255.165.320'], ['D12.776.256.159.750.816.500', 'D12.776.377.457'], ['E05.196.867.519'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['D10.627'], ['G02.712'], ['G02.723'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Introduction of a disulfide bond into ricin A chain decreases the cytotoxicity of the ricin holotoxin. | Wild type ricin A chain (RTA) contains two cysteine residues (Cys171 and Cys259). Cys259 forms the interchain disulfide bond of ricin holotoxin with Cys4 of ricin B chain (RTB). We have used site-directed mutagenesis of RTA cDNA to convert Cys171 to Ser and to introduce a disulfide bond into RTA by converting Ser215 an... | ['Animals', 'Chlorocebus aethiops', 'Cysteine', 'Cytotoxins', 'Disulfides', 'Dose-Response Relationship, Drug', 'Escherichia coli', 'HeLa Cells', 'Humans', 'Mutagenesis, Site-Directed', 'Oxidation-Reduction', 'Plant Lectins', 'Plants, Toxic', 'Protein Engineering', 'Protein Folding', 'RNA, Ribosomal', 'Recombinant Prot... | 7,929,403 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D27.888.569.213'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['G07.690.773.875', 'G07.690.936.500'], ['B03.440.450.425.325.300', 'B03.660.25... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lead exposure from lead pellets: age-related accumulation in mute swans. | In a cross-sectional study of adult swans and their successfully fledged young in Ringk?bing Fjord, West Jutland, Denmark, 128 venous blood samples were taken during the moulting period and analyzed for lead. While the juveniles generally showed blood lead levels below 15 micrograms/100 ml (median, 11 micrograms/100 ml... | ['Age Factors', 'Animals', 'Bird Diseases', 'Birds', 'Body Burden', 'Denmark', 'Environmental Exposure', 'Female', 'Lead', 'Lead Poisoning', 'Male'] | 6,719,507 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['C22.131'], ['B01.050.150.900.248'], ['E05.799.638.231', 'N06.850.460.200'], ['Z01.542.816.124'], ['N06.850.460.350'], ['D01.268.556.435', 'D01.552.544.435'], ['C25.723.522.750']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Carboxypeptidase Z (CPZ) modulates Wnt signaling and regulates the development of skeletal elements in the chicken. | Carboxypeptidase Z (CPZ) is a secreted Zn-dependent enzyme whose biological function is largely unknown. CPZ has a bipartite structure consisting of an N-terminal cysteine-rich domain (CRD) and a C-terminal catalytic domain. In the early chicken embryo CPZ is initially expressed throughout the somites and subsequently ... | ['Amino Acid Sequence', 'Animals', 'Carboxypeptidases', 'Chick Embryo', 'DNA-Binding Proteins', 'Gene Expression Regulation', 'Homeodomain Proteins', 'Humans', 'In Situ Hybridization', 'Molecular Sequence Data', 'Morphogenesis', 'PAX3 Transcription Factor', 'Paired Box Transcription Factors', 'Protein Binding', 'Proto-... | 12,944,424 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.277.656.350.245'], ['A13.350.150', 'A16.331.200'], ['D12.776.260'], ['G05.308'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.75... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rural Aging in America: Proceedings of the 2017 Connectivity Summit. | Rural Aging in America: Proceedings of the 2017 Connectivity Summit Alexis Skoufalos, EdD, Janice L. Clarke, RN, BBA, Dana Rose Ellis, BA, Vicki L. Shepard, MSW, MPA, and Elizabeth Y. Rula, PhD Editorial: Creating a Movement to Transform Rural Aging David B. Nash, MD, MBA, with Donato J. Tramuto, and Joseph F. Coughlin... | ['Aged', 'Aged, 80 and over', 'Health Services for the Aged', 'Humans', 'Rural Health Services', 'Rural Population', 'United States'] | 29,251,548 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N02.421.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.816'], ['N01.600.725'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pycnodysostosis associated with bilateral congenital pseudarthrosis of the clavicle. | We report the case of a 22-year-old woman with pycnodysostosis associated with bilateral congenital pseudarthrosis of the clavicle. The patient was first seen at the age of 19 years and had no symptoms during the 3-year follow-up period. The diagnosis of pycnodysostosis was made by typical clinical and radiological fin... | ['Abnormalities, Multiple', 'Adult', 'Clavicle', 'Facies', 'Female', 'Fingers', 'Humans', 'Pseudarthrosis', 'Radiography', 'Syndrome'] | 12,721,693 | [['C16.131.077'], ['M01.060.116'], ['A02.835.232.087.227'], ['C23.550.291.812', 'E01.370.600.230'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.404.468.627'], ['E01.370.350.700'], ['C23.550.288.500']] | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Why and how is soft copy reading possible in clinical practice? | The properties of the human visual system (HVS) relevant to the diagnostic process are described after a brief introduction on the general problems and advantages of using soft copy for primary radiology interpretations. At various spatial and temporal frequencies the contrast sensitivity defines the spatial resolution... | ['Adaptation, Ocular', 'Artifacts', 'Contrast Sensitivity', 'Data Display', 'Diagnostic Imaging', 'Flicker Fusion', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Light', 'Quality Assurance, Health Care', 'Radiology Information Systems', 'Space Perception', 'Technology, Radiologic', 'Vision, Ocu... | 10,036,662 | [['G14.020'], ['E05.047'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['F02.784.412.221', 'L01.296'], ['E01.370.350'], ['E01.370.380.245', 'F02.463.593.932.458', 'G14.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.3... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Expression of BET genes in testis of men with different spermatogenic impairments. | OBJECTIVE: To characterize the BET gene expression in human testis with spermatogenetic impairments; to examine BRDT protein expression in testis and semen.DESIGN: Prospective study.SETTING: Fertility clinic.PATIENT(S): Azoospermic men (n = 120) who underwent testicular sperm extraction and who were classified as eithe... | ['Azoospermia', 'Biopsy', 'Cell Cycle Proteins', 'Epigenesis, Genetic', 'Gene Expression', 'Humans', 'Male', 'Nuclear Proteins', 'Prospective Studies', 'Protein-Serine-Threonine Kinases', 'RNA-Binding Proteins', 'Sertoli Cell-Only Syndrome', 'Spermatids', 'Spermatogenesis', 'Spermatozoa', 'Transcription Factors'] | 22,035,730 | [['C12.294.365.700.380'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D12.776.167'], ['G05.308.203'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['E05.318.372.500.750.625', 'N05.715.3... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Efficacy of bunazosin hydrochloride 0.01% as adjunctive therapy of latanoprost or timolol. | PURPOSE: To evaluate the ocular hypotensive response of bunazosin hydrochloride 0.01% administered as adjunctive therapy in patients with glaucoma who were already receiving latanoprost 0.005% or timolol 0.5%.METHODS: Patients with primary open angle glaucoma who had received latanoprost (n = 60) or timolol (n = 60) fo... | ['Adrenergic alpha-Antagonists', 'Adrenergic beta-Antagonists', 'Aged', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Latanoprost', 'Male', 'Middle Aged', 'Prostaglandins F, Synthetic', 'Pupil', 'Quinazolines', 'Timolol'] | 14,704,548 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116.100'], ['E02.319.283'], ['E02.319.310'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['D10.251.355.255.550.775.500.587', 'D23.469.050.175.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Phylogeography, geographic structure, genetic variation, and potential species boundaries in Philippine slender toads. | We investigated phylogeography of Philippine slender toads (genus Ansonia) and used a temporal framework for diversification, statistical tests of alternate topologies, and Bayesian approaches to test previous hypotheses concerning dispersal to, and colonization routes within, the southern Philippine island of Mindanao... | ['Animals', 'Bayes Theorem', 'Biological Evolution', 'Bufonidae', 'DNA, Mitochondrial', 'Genetic Speciation', 'Genetic Variation', 'Genetics, Population', 'Likelihood Functions', 'Philippines', 'Phylogeny', 'Phylogeography', 'Sequence Analysis, DNA'] | 21,757,017 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G05.045', 'G16.075'], ['B01.050.150.900.090.180.210'], ['D13.444.308.283.225'], ['G05.045.350', 'G16.075.350'], ['G05.365'], ['H01.158.273.343.335'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Rehmannia glutinosa | Nanomedicine, the medical application of nanotechnology, promises a seemingly limitless range of applications from drug delivery to adjuvants and therapeutics. Our current research is focused on natural polymer-based liposome adjuvants. With the aim of inducing protective and long-lasting immunity, the immunological ad... | ['Adjuvants, Immunologic', 'Animals', 'Antigen Presentation', 'B7-2 Antigen', 'CD11c Antigen', 'Cell Differentiation', 'Cell Proliferation', 'Cytokines', 'Dendritic Cells', 'Female', 'Immunoglobulin G', 'Immunohistochemistry', 'Immunologic Memory', 'Liposomes', 'Lymph Nodes', 'Lymphocytes', 'Male', 'Mice', 'Mice, Inbre... | 28,008,254 | [['D27.505.696.477.067'], ['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['D12.776.465.500', 'D12.776.467.150.200', 'D12.776.543.095.200', 'D23.050.301.285.200', 'D23.529.168.200'], ['D12.776.395.550.200.074.875', 'D12.776.395.550.200.275.500', 'D12.776.543.550.200.093.875', 'D12.776.543.550.200.275.500', 'D12.776.54... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Autoimmune and lymphoproliferative disease in (B6-GIX+ X 129)F1 mice: relation to naturally occurring antibodies against murine leukemia virus-related cell surface antigens. | G(IX) congeneic mouse strains, C57BL/6-G(IX) (+)(B6-G(IX) (+)) and 129-G(IX) (-), have been derived from the prototype strains, B6(G(IX) (-)) and 129(G(IX) (+)). The hybrids, (B6-G(IX) (+) x 129)F(1) (G(IX) (+)F(1)) and (B6 x 129-G(IX) (-))F(1) (G(IX) (-)F(1)), differ only in regard to genetic loci controlling G(IX) an... | ['Animals', 'Antibodies', 'Antibody Formation', 'Antigens, Surface', 'Autoimmune Diseases', 'Disease Models, Animal', 'Female', 'Hybridization, Genetic', 'Leukemia Virus, Murine', 'Lupus Erythematosus, Systemic', 'Lymphoproliferative Disorders', 'Male', 'Mice', 'Mice, Inbred Strains'] | 228,283 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A new case of Mycobacterium bovis pulmonary tuberculosis in the dromedary (Camelus dromedarius) in Mauritania]. | A case of pulmonary tuberculosis is described in a dromedary from Nouakchott (Mauritania). Gross lesions affected pulmonary parenchyma, diaphragmatic pleura, pericardium and regional lymph nodes: caseo-calcified nodules, miliary tubercles and haemorrhagic "pendeloques". Microscopically lesions were characterised by gra... | ['Animals', 'Camelus', 'Mauritania', 'Mycobacterium bovis', 'Tuberculosis, Pulmonary'] | 1,775,689 | [['B01.050'], ['B01.050.150.900.649.313.500.190.180'], ['Z01.058.290.190.520'], ['B03.510.024.962.500.402', 'B03.510.460.400.410.552.552.402'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.730.939']] | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Scavenging effects of baicalin on free radicals and its protection on erythrocyte membrane from free radical injury. | Using electron spin resonance (ESR) spin trapping technique, we found that baicalin (B) could scavenge hydroxyl radicals generated from Fenton reaction. It also could scavenge superoxide radicals generated from the reaction system containing xanthine (X) and xanthine oxidase (XO), as was found by using chemiluminescenc... | ['Anions', 'Anti-Infective Agents', 'Antiviral Agents', 'Binding Sites', 'Drugs, Chinese Herbal', 'Erythrocyte Membrane', 'Flavonoids', 'Free Radical Scavengers', 'Free Radicals', 'Hemolysis', 'Humans', 'Hydrogen Peroxide', 'Hydroxyl Radical', 'Iron', 'Kinetics', 'Membrane Proteins', 'Protein Conformation', 'Reperfusio... | 7,549,941 | [['D01.248.497.158'], ['D27.505.954.122'], ['D27.505.954.122.388'], ['G02.111.570.120'], ['D20.215.784.500.350', 'D26.335'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D27.505.519.217.500'], ['D01.339', 'D02.389'], ['C23.550.403', 'G12.122.54... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relative biological effectiveness of intermediate energy protons. Comparisons with 60Co gamma-radiation using two cell lines. | Range modulated proton beams are used for radiotherapy of malignant tumours at several accelerator laboratories with the aim of introducing proton therapy as a clinical hospital-based therapy modality. Due to the finite range and the sharpness of the dose gradients, the dose to well defined target volumes can be raised... | ['Animals', 'Cell Line', 'Cell Survival', 'Cobalt Radioisotopes', 'Colonic Neoplasms', 'Cricetinae', 'Gamma Rays', 'Humans', 'Protons', 'Radiation Dosage', 'Relative Biological Effectiveness', 'Tumor Cells, Cultured'] | 8,234,869 | [['B01.050'], ['A11.251.210'], ['G04.346'], ['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A/R systems reduce delayed and denied reimbursements. | The day-to-day benefits of a comprehensive billing and collections system are pro-active and preventive--administrators are increasingly learning that accelerating billings hastens collections and, ultimately, facility profitability. Effective billing and collections management services work closely with the facility, ... | ['Accounts Payable and Receivable', 'Diagnostic Imaging', 'Efficiency, Organizational', 'Insurance, Health, Reimbursement', 'Management Information Systems', 'United States'] | 17,471,813 | [['N03.219.463.030.080'], ['E01.370.350'], ['N04.452.209.500'], ['N03.219.521.576.343.480', 'N03.219.521.710'], ['N04.452.515'], ['Z01.107.567.875']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B. | Invasiveness is one of the key features of aggressive prostate cancer; however, our understanding of the precise mechanisms effecting invasion remains limited. The ceramide hydrolyzing enzyme acid ceramidase (AC), overexpressed in most prostate tumors, causes an aggressive and invasive phenotype through downstream effe... | ['Acid Ceramidase', 'Cathepsin B', 'Cell Line, Tumor', 'Cell Membrane', 'Cell Movement', 'Humans', 'Lysophospholipids', 'Male', 'Neoplasm Invasiveness', 'Promoter Regions, Genetic', 'Prostatic Neoplasms', 'Proto-Oncogene Protein c-ets-1', 'Sphingosine', 'Up-Regulation'] | 22,322,590 | [['D08.811.277.087.250.100'], ['D08.811.277.656.224.125', 'D08.811.277.656.262.500.133', 'D08.811.277.656.300.200.133'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.149'], ['G04.198', 'G07.568.500.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.570.755.375.760.550'], ['C04.697.645', 'C23.550.727.645... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cytological picture of the cerebrospinal fluid and the neuropathological changes in the central nervous system in acute leukemia in adults]. | Twenty-one patients with acute leukaemias were studied carrying out cytological investigations of the cerebrospinal fluid and then postmortem neuropathological examinations. The aim of the study was a comparison of these results. No correlation was demonstrated between CSF changes and the extent and location of leukaem... | ['Adolescent', 'Adult', 'Cerebellar Neoplasms', 'Cerebellum', 'Cerebrospinal Fluid', 'Humans', 'Leukemia, Lymphoid', 'Meningeal Neoplasms', 'Middle Aged', 'Pia Mater'] | 6,961,294 | [['M01.060.057'], ['M01.060.116'], ['C04.588.614.250.195.411.211', 'C10.228.140.211.500.200', 'C10.228.140.252.200', 'C10.551.240.250.400.300'], ['A08.186.211.132.810.428.200'], ['A12.207.270.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428', 'C15.604.515.560', 'C20.683.515.528'], ['C04.588.614... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency. | Germline mutations of the fumarate hydratase (FH, fumarase) gene are found in the recessive FH deficiency syndrome and in dominantly inherited susceptibility to multiple cutaneous and uterine leiomyomatosis (MCUL). We have previously reported a number of germline FH mutations from MCUL patients. In this study, we repor... | ['Amino Acid Metabolism, Inborn Errors', 'Amino Acid Sequence', 'Enzyme Stability', 'Female', 'Fumarate Hydratase', 'Genetic Predisposition to Disease', 'Germ-Line Mutation', 'Humans', 'Kidney Neoplasms', 'Leiomyomatosis', 'Molecular Sequence Data', 'Mutation', 'Protein Conformation', 'RNA Stability', 'RNA, Messenger',... | 12,761,039 | [['C16.320.565.100', 'C18.452.648.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.916.360', 'G02.111.700.500'], ['D08.811.520.241.300.300'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.365.590.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473'... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Accelerated hypertension caused by severe phimosis. | A 16 year old boy presented with accelerated hypertension and urinary tract obstruction caused by phimosis. Relief of the obstruction by circumcision reversed the hypertension. We believe that accelerated hypertension secondary to phimosis has not previously been described. | ['Adolescent', 'Atenolol', 'Blood Pressure', 'Humans', 'Hypertension', 'Male', 'Nifedipine', 'Phimosis', 'Urination Disorders'] | 1,597,850 | [['M01.060.057'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D03.383.725.203.540'], ['C12.294.494.684'], ['C12.777.934', 'C13.351.968.934']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of a preference-based index from the National Eye Institute Visual Function Questionnaire-25. | IMPORTANCE: Understanding how individuals value health states is central to patient-centered care and to health policy decision making. Generic preference-based measures of health may not effectively capture the impact of ocular diseases. Recently, 6 items from the National Eye Institute Visual Function Questionnaire-2... | ['Adult', 'Algorithms', 'Cross-Sectional Studies', 'Female', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'National Eye Institute (U.S.)', 'Quality of Life', 'Quality-Adjusted Life Years', 'Sickness Impact Profile', 'Surveys and Questionnaires', 'United States', 'Visual Acuity'] | 24,435,696 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.409.418.750.600.650.496.200', 'N03.540.052.750.200', 'N03.540.34... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Targeting PI3Kä function for amelioration of murine chronic graft-versus-host disease. | Chronic graft-versus-host disease (cGVHD) is a leading cause of morbidity and mortality following allotransplant. Activated donor effector T cells can differentiate into pathogenic T helper (Th)-17 cells and germinal center (GC)-promoting T follicular helper (Tfh) cells, resulting in cGVHD. Phosphoinositide-3-kinase-ä ... | ['Animals', 'B-Lymphocytes', 'Bone Marrow Transplantation', 'Bronchiolitis Obliterans', 'Chronic Disease', 'Class I Phosphatidylinositol 3-Kinases', 'Disease Models, Animal', 'Graft vs Host Disease', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mice, Mutant Strains', 'Phosphoinositi... | 30,748,099 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E02.095.147.725.040', 'E04.936.580.040'], ['C08.127.446.135.140', 'C08.381.495.146.135.140'], ['C23.550.291.500'], ['D08.811.913.696.620.500.100.100', 'D08.811.913.696.620.500.200.100... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brief treatments with forskolin enhance s-phase entry in balance epithelia from the ears of rats. | In the ears of mammals, hair cell loss results in permanent hearing and balance deficits, whereas in fish, amphibians, and birds, the production of replacement hair cells can restore those modalities. In avian ears, continuous exposures to forskolin trigger cell proliferation and the regeneration of hair cells, so we i... | ['8-Bromo Cyclic Adenosine Monophosphate', 'Animals', 'Anti-Bacterial Agents', 'Bromodeoxyuridine', 'Cell Division', 'Cells, Cultured', 'Colforsin', 'Cyclic AMP-Dependent Protein Kinases', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Epithelial Cells', 'Hair Cells, Vestibular', 'Ionophores', 'Macrolides', ... | 11,157,083 | [['D03.633.100.759.646.138.395.225', 'D13.695.462.200.225', 'D13.695.667.138.395.225', 'D13.695.827.068.395.225'], ['B01.050'], ['D27.505.954.122.085'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression profiling defines a recurrence signature in lung squamous cell carcinoma. | Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is approximately 10-15% and despite curative intent surgery, treatment failure is primarily due to recurrent disease. Conventional prognostic markers are unable to determine which patients with completely resected disease within ea... | ['Aged', 'Carcinoma, Squamous Cell', 'Female', 'Gene Expression Profiling', 'Humans', 'Lung Neoplasms', 'Male', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Prognosis', 'Recurrence', 'Survival Analysis', 'Treatment Outcome'] | 17,082,175 | [['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.645', 'C23.550.727.645'], ['E01.789.625'], ['E01.789'], ['C23.550.291.937'], ['E05.318.740.998', 'N05.715.360.750.795',... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of Bax-voltage-dependent anion channel 1 complexes in digitonin-solubilized cerebellar granule neurons. | Mitochondrial outer membrane Bax oligomers are critical for cytochrome c release, but the role of resident mitochondrial proteins in this process remains unclear. Membrane-associated Bax has primarily been studied using 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) as the solubilizing agent, as it d... | ['Animals', 'Animals, Newborn', 'Cerebellar Cortex', 'Cholic Acids', 'Cytoplasmic Granules', 'Digitonin', 'Neurons', 'Primary Cell Culture', 'Rats', 'Rats, Wistar', 'Solubility', 'Voltage-Dependent Anion Channel 1', 'bcl-2-Associated X Protein'] | 21,951,169 | [['B01.050'], ['B01.050.050.282'], ['A08.186.211.132.810.428.200.212'], ['D04.210.500.105.225', 'D04.210.500.221.430'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['D04.210.500.155.580.130.500.236', 'D09.408.180.261.236'], ['A08.675', 'A11.671'], ['E01.370.225.500.223.500', 'E05.200.500.265.500', '... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sinusitis as an emergency. | The manifestations of diseases of the paranasal sinuses that may present as acute emergency situations and the more common complications of these diseases are briefly reviewed with suggestions for initial evaluation therapy. | ['Adult', 'Bacterial Infections', 'Cavernous Sinus', 'Child', 'Diagnosis, Differential', 'Drainage', 'Emergencies', 'Ethmoid Sinus', 'Frontal Sinus', 'Humans', 'Maxillary Sinus', 'Radiography', 'Sinus Thrombosis, Intracranial', 'Sinusitis'] | 460,884 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Free space optical link for biomedical applications. | Free space optics is an interesting alternative for telemetry with medical implants, due to the high data bandwidths available at optical frequencies. Especially implanted brain-computer interfaces gives rise to large data sets that needs to be transmitted transcutaneous. In this paper we show that it is possible to es... | ['Animals', 'Biomedical Technology', 'Computer Simulation', 'In Vitro Techniques', 'Mice', 'Models, Theoretical', 'Monte Carlo Method', 'Optics and Photonics', 'Rats', 'Signal-To-Noise Ratio', 'Skin Physiological Phenomena'] | 23,366,228 | [['B01.050'], ['J01.897.120.050'], ['L01.224.160'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['H01.671.617', 'J01.293.688'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.318.370.800.875', 'E05.318.7... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Osteogenic differentiation strategies for adipose-derived mesenchymal stem cells. | Adipose stem cell preparations, either obtained as a freshly isolated so-called stromal vascular fraction (SVF) or as cells cultured to homogeneity and then referred to as adipose stem cells (ASCs), have found widespread use in a broad variety of studies on tissue engineering and regenerative medicine applications, inc... | ['Adipose Tissue', 'Alkaline Phosphatase', 'Animals', 'Anthraquinones', 'Bone Morphogenetic Protein 2', 'Bone Morphogenetic Protein 7', 'Calcitriol', 'Cell Culture Techniques', 'Cell Differentiation', 'Cells, Cultured', 'Colony-Forming Units Assay', 'Goats', 'Humans', 'Immunohistochemistry', 'Integrin-Binding Sialoprot... | 21,082,406 | [['A10.165.114'], ['D08.811.277.352.650.035'], ['B01.050'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['D12.644.276.954.200.700', 'D12.776.467.942.200.700', 'D23.529.942.200.700'], ['D04.210.500.247.222.159.478.387.3... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimum replacement dose of thyroid hormone assessed by highly sensitive TSH determination in patients with congenital hypothyroidism. | Serum thyroid hormone concentrations were measured in 100 samples from 25 patients with congenital hypothyroidism who were clinically well while receiving L-T4 therapy. Thyroxine concentrations were significantly higher than those of controls (p less than 0.01), while triiodothyronine was not significantly different. T... | ['Child', 'Child, Preschool', 'Congenital Hypothyroidism', 'Humans', 'Hypothyroidism', 'Radioimmunoassay', 'Thyrotropin', 'Thyroxine', 'Triiodothyronine'] | 3,215,142 | [['M01.060.406'], ['M01.060.406.448'], ['C05.116.099.343.347', 'C05.116.132.256', 'C16.320.240.625', 'C19.297.155', 'C19.874.482.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['D06.472.699.631.525.883', 'D12.644.548.691.525.883'], ['D... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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