Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration. | We assessed the feasibility of transplanting a sheet of retinal pigment epithelial (RPE) cells differentiated from induced pluripotent stem cells (iPSCs) in a patient with neovascular age-related macular degeneration. The iPSCs were generated from skin fibroblasts obtained from two patients with advanced neovascular ag... | ['Aged', 'Cell Culture Techniques', 'Cell Differentiation', 'Feasibility Studies', 'Female', 'Fibroblasts', 'Humans', 'Induced Pluripotent Stem Cells', 'Macular Degeneration', 'Male', 'Retinal Pigment Epithelium', 'Transplantation, Autologous'] | 28,296,613 | [['M01.060.116.100'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.040.500', 'A11.872.700.500'], ['C11.768.585.439']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Study and preparation of a novel apatite-wollastonite bioactive glass-ceramic-calcium sulphate hemihydrate composite]. | OBJECTIVE: To prepare a novel apatite-wollastonite bioactive glass-ceramic-calcium sulphate hemihydrate(AW-BGC-CSH) composite, to study its biocompatibility, and to provide experimental support for its further clinical application.METHODS: Samples of AW-BGC-CSH composite were prepared with different AW-BGC granules-CSH... | ['Apatites', 'Biocompatible Materials', 'Calcium Compounds', 'Calcium Sulfate', 'Cells, Cultured', 'Ceramics', 'Materials Testing', 'Osteoblasts', 'Silicates'] | 21,122,439 | [['D01.029.260.700.675.374.075.025', 'D01.146.360.050', 'D01.578.122', 'D01.695.625.675.650.075.025'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D01.146'], ['D01.146.375', 'D01.578.215', 'D01.875.800.800.850.125'], ['A11.251'], ['J01.637.153'], ['E05.570'], ['A11.329.629'], ['D01.578.725', 'D01.837.725.700.7... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[SELECTIVE EFFICACY OF GEORGIAN LEGUME EXTRACTS ON JURKAT AND MDCK CELLS]. | The goal of our study was to establish the anti- proapoptotic activity of the common in Georgia crops on the Jurkat and MDCK cells. Extracts of various varieties of beans (Tirkmela, Batumi meadow, Shulavera, Udelebi, as well as green peas, Lens Culinaris lentils, soy beans) were added to the intact or incubated under o... | ['Animals', 'Apoptosis', 'Dogs', 'Fabaceae', 'Humans', 'Hydrogen Peroxide', 'Jurkat Cells', 'Madin Darby Canine Kidney Cells', 'Oxidative Stress', 'Plant Extracts'] | 31,101,797 | [['B01.050'], ['G04.146.954.035'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.650.940.800.575.912.250.401'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The human transforming growth factor alpha promoter directs transcription initiation from a single site in the absence of a TATA sequence. | Transforming growth factor alpha (TGF-alpha) is a transformation-responsive mitogenic polypeptide that is expressed in the brain, epithelial cells, and activated macrophages. We isolated and characterized the TGF-alpha promoter and localized the 5' end of the TGF-alpha transcript to a unique position. Surprisingly, no ... | ['Amino Acid Sequence', 'Base Sequence', 'Chimera', 'Genes', 'Genes, Homeobox', 'Humans', 'Molecular Sequence Data', 'Plasmids', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Restriction Mapping', 'Transcription, Genetic', 'Transforming Growth Factors'] | 2,907,605 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B05.200'], ['G05.360.340.024.340'], ['G05.360.340.024.340.230.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['G05.360.600'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.36... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Resident Participation is Not Associated With Worse Outcomes After TKA. | BACKGROUND: Approximately one-half of all US surgical procedures, and one-third of orthopaedic procedures, are performed at teaching hospitals. However, the effect of resident participation and their level of training on patient care for TKA postoperative physical function, operative time, length of stay, and facility ... | ['Adult', 'Aged', 'Arthroplasty, Replacement, Knee', 'Clinical Competence', 'Female', 'Humans', 'Internship and Residency', 'Male', 'Middle Aged', 'Minimal Clinically Important Difference', 'Orthopedic Surgeons', 'Physical Functional Performance', 'Postoperative Period', 'Retrospective Studies', 'Treatment Outcome'] | 29,480,888 | [['M01.060.116'], ['M01.060.116.100'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['M01.060.116.630'], ['N04.761.559.590.399.750', 'N05.715.360.575.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Automated nucleic acid isolation in viral molecular diagnostics: evaluation of the QIAsymphony SP. | The Qiagen QIAsymphony SP is a high-throughput (up to 96 samples per run), fully-automated nucleic acid isolation system. It was implemented in the authors' laboratory to cope with the high demand for pandemic H1N1 influenza testing in 2009. This study evaluated the QIAsymphony SP for viral nucleic acid isolation from ... | ['Animals', 'Automation, Laboratory', 'Cells, Cultured', 'Chick Embryo', 'DNA, Viral', 'Dogs', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Nucleic Acids', 'Pathology, Molecular', 'Polymerase Chain Reaction', 'Quality Control', 'RNA, Viral', 'Reagent Kits, Diagnostic', 'Real-Time Polymerase Chain Reaction'] | 22,558,800 | [['B01.050'], ['E05.064', 'J01.897.104.416'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D13.444.308.568'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['D13.444'], ['H01.158.201.636.475.750', 'H01.158.273.343.595.475.750', 'H01.181.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparison of hospital databases on antibiotic consumption in France, for a single management tool. | CONTEXT: The surveillance of antibiotic use in hospitals and of data on resistance is an essential measure for antibiotic stewardship. There are 3 national systems in France to collect data on antibiotic use: DREES, ICATB, and ATB RAISIN. We compared these databases and drafted recommendations for the creation of an op... | ['Anti-Bacterial Agents', 'Automation', 'Benchmarking', 'Cross Infection', 'Data Collection', 'Database Management Systems', 'Databases, Factual', 'Drug Utilization', 'France', 'Humans', 'Inappropriate Prescribing', 'Pharmacy Service, Hospital', 'Qualitative Research'] | 25,015,309 | [['D27.505.954.122.085'], ['J01.897.104'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['C01.248', 'C23.550.291.875.500'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['L01.224.068', 'L01.224.900.280', 'N04.452.515.110'], ['L01.313.500.750.3... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Ingestion of bar soap may produce serious injury: clinical effects and risk factors. | INTRODUCTION: Most household and body soaps have an alkaline pH (9-12). In addition to their foaming effect, they irritate the skin. This study aims to review soap exposure reported to the Angers Poison Control Centre.METHOD: A retrospective study of accidental or deliberate oral exposure to solid soaps reported to the... | ['Accidents, Home', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Dementia', 'Edema', 'Female', 'France', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Poisoning', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Severity of Illness Index', 'Soaps', 'Voli... | 30,307,335 | [['N06.850.135.217'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['C10.228.140.380', 'F03.615.400'], ['C23.888.277'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.116.630'], ['... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Melatonin alleviates behavioral deficits associated with apoptosis and cholinergic system dysfunction in the APP 695 transgenic mouse model of Alzheimer's disease. | Melatonin is an endogenous antioxidant and free radical scavenger. A transgenic (Tg) mouse model for Alzheimer's disease mimics the accumulation of senile plaques, neuronal apoptosis and memory impairment. Previous studies indicated that melatonin reduced beta-amyloid (Abeta)-induced neurotoxicity. In this study, after... | ['Alzheimer Disease', 'Amyloid beta-Peptides', 'Animals', 'Apoptosis', 'Behavior, Animal', 'Brain', 'Choline O-Acetyltransferase', 'Cholinergic Fibers', 'Disease Models, Animal', 'In Situ Nick-End Labeling', 'Learning', 'Melatonin', 'Memory', 'Mice', 'Mice, Transgenic', 'Neuroprotective Agents'] | 15,298,672 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['G04.146.954.035'], ['F01.145.113'], ['A08.186.211'], ['D08.811.913.050.134.180'], ['A08.675.127.500', 'A08.675.542.234', 'A11.671.188.500', 'A11.671.501.234'], ['C22.232', 'E... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Background reduction at DTU Nutech surface gamma laboratory. | Sources of background and background variation in a BEGe type HPGe detector located in a surface laboratory were identified. Different strategies for background reduction were applied. A cosmic veto was installed, and optimised using a digital acquisition system in list-mode with time-stamped data. This resulted in the... | ['Air Pollutants, Radioactive', 'Radiation Monitoring', 'Radon', 'Spectrometry, Gamma'] | 31,158,703 | [['D20.693.101', 'D27.888.284.101.393'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['D01.268.271.800', 'D01.268.613.700', 'D01.362.641.745', 'D01.496.749.305.800'], ['E05.196.867.776', 'E05.799.801']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dyserythropoiesis and annulate lamellae. | Cytoplasmic and intranuclear annulate lamellae in the erythroblasts from patients with dyserythropoietic anaemia (megaloblastic anaemia, dysplastic anaemia and erythroleukaemia) are described. Annulate lamellae have mainly been observed in oocytes, in embryonic tissues and in malignant cells. Their occurrence in dysery... | ['Anemia, Macrocytic', 'Anemia, Megaloblastic', 'Cytoplasm', 'Erythroblasts', 'Erythropoiesis', 'Fetal Hemoglobin', 'Humans', 'Leukemia, Erythroblastic, Acute'] | 1,059,475 | [['C15.378.071.252'], ['C15.378.071.252.196'], ['A11.284.430.214'], ['A11.148.378.590.837.250.200', 'A11.443.240.497.200', 'A15.378.316.378.590.837.250.200'], ['G04.152.825.414', 'G09.188.343.414'], ['D12.776.124.400.303', 'D12.776.422.316.762.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.27... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relationship of breakfast skipping and type of breakfast consumed with overweight/obesity, abdominal obesity, other cardiometabolic risk factors and the metabolic syndrome in young adults. The National Health and Nutrition Examination Survey (NHANES): 1999-2006. | OBJECTIVE: To examine the association between breakfast skipping and type of breakfast consumed with overweight/obesity, abdominal obesity, other cardiometabolic risk factors and the metabolic syndrome (MetS).DESIGN: Cross-sectional. Three breakfast groups were identified, breakfast skippers (BS), ready-to-eat-cereal (... | ['Adult', 'Blood Pressure', 'Breakfast', 'Cardiovascular Diseases', 'Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Cross-Sectional Studies', 'Diet', 'Diet Records', 'Edible Grain', 'Fast Foods', 'Feeding Behavior', 'Female', 'Humans', 'Hypertension', 'Insulin', 'Male', 'Mental Recall', 'Metabolic Syndrome', 'N... | 23,031,568 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.203.300.590.120', 'J02.500.590.120'], ['C14'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Young adults' attitudes to sharing whole-genome sequencing information: a university-based survey. | BACKGROUND: Genomic services are increasingly accessible to young adults starting their independent lives with responsibility for their self-care, yet their attitudes to sharing genomic information remain under-researched. This study explored attitudes of university-based 18-25 year-olds towards sharing personal whole-... | ['Family', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Information Dissemination', 'Male', 'Policy Making', 'Surveys and Questionnaires', 'Universities', 'Whole Genome Sequencing', 'Young Adult'] | 30,991,996 | [['F01.829.263', 'I01.880.853.150'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['N03.706.742'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['I02.783.830', 'J03.832.830'], ['E05.393.760.700.825'], ['M01.060.116.815']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
Renal phosphorus excretion in adult healthy cats after the intake of high phosphorus diets with either calcium monophosphate or sodium monophosphate. | Renal and faecal phosphorus excretion of adult healthy European shorthaired cats after the intake of high phosphorus diets (meat/rice based) with either calcium monophosphate (HP-CaP) or sodium monophosphate (HP-NaP) as main phosphorus source was compared. The control diets (CON-CaP and CON-NaP, respectively) did not c... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Calcium Phosphates', 'Cats', 'Cross-Over Studies', 'Diet', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Feces', 'Female', 'Male', 'Phosphates', 'Phosphorus', 'Phosphorus, Dietary', 'Urinalysis'] | 30,151,843 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.203.650.240'], ['G07.690.773.875', 'G07.690.... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AáC) in human bladder RT4 cells. | Occupational and tobacco exposure to aromatic amines (AAs) including 4-aminobiphenyl (4-ABP) and 2-naphthylamine (2-NA) are associated with bladder cancer (BC) risk. Several epidemiological studies have also reported a possible role for structurally related heterocyclic aromatic amines (HAAs) formed in tobacco smoke or... | ['2-Naphthylamine', 'Aminobiphenyl Compounds', 'Carbolines', 'Carcinogens', 'Cell Line', 'Chromatography, Liquid', 'DNA Adducts', 'DNA Damage', 'Humans', 'Mass Spectrometry', 'Urinary Bladder'] | 31,203,411 | [['D02.092.710', 'D02.455.426.559.847.638.850', 'D04.615.638.850'], ['D02.455.426.559.389.185.060'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['D27.888.569.100'], ['A11.251.210'], ['E05.196.181.400'], ['D13.444.308.135', 'G05.200.104'], ['G05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of counter-ions and penetration enhancers on the skin permeation of flurbiprofen. | The aim of this work was to investigate the percutaneous absorption of flurbiprofen (FP) using counter-ions as enhancers as well as to compare their enhancing activity with penetration enhancers in vitro. The in vitro permeation studies of FP were performed in isopropyl myristate (IPM) solution by two-chamber diffusion... | ['Amines', 'Animals', 'Ethanol', 'Flurbiprofen', 'Ions', 'Magnetic Resonance Spectroscopy', 'Male', 'Propylene Glycol', 'Rats', 'Rats, Wistar', 'Skin', 'Skin Absorption'] | 19,894,269 | [['D02.092'], ['B01.050'], ['D02.033.375'], ['D02.241.081.751.161', 'D02.455.426.559.389.185.350'], ['D01.248.497'], ['E05.196.867.519'], ['D02.033.455.706.725'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A17.815'], ['G03.015.500.750', 'G03.787.024.500.750', 'G07.69... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of calcium dobesilate on permeation of plasma proteins in diabetic patients]. | The effect of six months of treatment with 750 mg calcium dobesilate on sedimentation rate blood count, cholesterol, triglycerides, platelet aggregation factor, total protein, electrophoretic distribution of serum protein concentrations, and kinetics of intravenous albumin marked with 131I was established in 35 diabeti... | ['Aged', 'Benzenesulfonates', 'Beta-Globulins', 'Blood Proteins', 'Blood Sedimentation', 'Calcium Dobesilate', 'Capillary Permeability', 'Cholesterol', 'Diabetes Mellitus', 'Humans', 'Middle Aged', 'Platelet Aggregation', 'Serum Albumin', 'Triglycerides'] | 6,160,031 | [['M01.060.116.100'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['D12.776.124.790.223', 'D12.776.377.715.182'], ['D12.776.124'], ['E01.370.225.625.125', 'E05.200.625.125'], ['D02.455.426.559.389.097.120', 'D02.886.645.600.080.050.100.075'], ['G03.143.330', 'G09.330.165'], ['D04.210.500.247.222.284', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Sodium- and water balance in the dog in the conscious state and under nitrous-oxide and barbiturate anesthesia (author's transl)]. | By a suitable pattern of saline infusion we established an equilibrium between input and renal output of sodium and water in the conscious animal, which was maintained for six hours. During this period of equilibrium we found an increase in GFR, plasma volume and functional ECFV of about 30% each, the amount of intrava... | ['Anesthesia', 'Animals', 'Barbiturates', 'Dogs', 'Extracellular Space', 'Female', 'Nitrous Oxide', 'Plasma Volume', 'Sodium', 'Water-Electrolyte Balance'] | 1,217,690 | [['E03.155'], ['B01.050'], ['D03.383.742.698.253'], ['B01.050.150.900.649.313.750.250.216.200'], ['A10.082.500', 'A11.284.295'], ['D01.362.635.625', 'D01.625.550.550', 'D01.650.550.587.650'], ['G09.188.130.610', 'G09.330.380.092.610'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725'], ['G02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparation and characterization of cotton fabric with potential use in UV resistance and oil reclaim. | Here we report a simple, facile and low-cost approach to the cotton textile with significant properties. After treatment, the cotton textiles exhibit not only an excellent superhydrophobicity with the water contact angle (WCA) of 151.5(o), but also an efficient shielding property against UV with the transmittance under... | ['Cotton Fiber', 'Hydrophobic and Hydrophilic Interactions', 'Textiles', 'Ultraviolet Rays'] | 26,686,129 | [['J01.637.836.299'], ['G02.409'], ['J01.637.836'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.750.659', 'G01.750.770.578.891', 'G16.500.275.063.725.525.600', 'G16.500.750.775.525.600', 'N06.230.300.100.725.525.600']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Evaluating and prescribing new medicines in general practice. | BACKGROUND: In Australia, the Therapeutic Goods Administration (TGA) approves new medicines that general practitioners (GPs) may prescribe. Medicines listed under the Pharmaceutical Benefits Scheme (PBS) have undergone a rigorous independent evaluation in relation to comparative efficacy, safety and effectiveness again... | ['Australia', 'Decision Making', 'Drug Prescriptions', 'General Practitioners', 'Humans', "Practice Patterns, Physicians'"] | 29,966,181 | [['Z01.639.100', 'Z01.678.100.373'], ['F02.463.785.373'], ['E02.319.307', 'N02.421.668.778.500'], ['M01.526.485.810.485', 'N02.360.810.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.374.577', 'N05.300.625']] | ['Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Noninvasive measurements of nonlinear arterial elasticity. | To describe fully the compliance characteristics of an artery with nonlinear elastic properties, measurements must be obtained over a wide range of pressures. Furthermore, repeated measurements, as required in temporal studies of arterial implants, require that the measuring technique be noninvasive. The application of... | ['Animals', 'Arteries', 'Blood Flow Velocity', 'Dogs', 'Elasticity', 'Femoral Artery', 'Hypotension', 'Mathematics', 'Pressure', 'Rheology', 'Ultrasonics'] | 3,946,617 | [['B01.050'], ['A07.015.114'], ['E01.370.370.130', 'G09.330.380.630.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['G01.374.590'], ['A07.015.114.351'], ['C14.907.514'], ['H01.548'], ['G01.374.715'], ['E05.830', 'H01.671.808'], ['H01.671.031.849']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Study of genetic variance in the fluctuating asymmetry of anthropometrical traits. | We have studied the fluctuating asymmetry (FA) of 8 bilateral morphometric traits in two-parent families, comprising 216 families with one newborn baby, and 60 families with two children (age range 5-18 years). Heritability was assessed by: (1) multiple regression analyses of the children's measurements on the mother's... | ['Adolescent', 'Adult', 'Anthropometry', 'Child', 'Child, Preschool', 'Family', 'Female', 'Genetic Variation', 'Humans', 'Infant, Newborn', 'Israel', 'Male', 'Nuclear Family'] | 2,729,889 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.060.406'], ['M01.060.406.448'], ['F01.829.263', 'I01.880.853.150'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['Z01.252.245.500.375'], ['F01.829.263.500', 'I01.880.853.150.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
X-ray absorption spectroscopy of the copper chaperone HAH1 reveals a linear two-coordinate Cu(I) center capable of adduct formation with exogenous thiols and phosphines. | The human copper chaperone HAH1 transports copper to the Menkes and Wilson proteins, which are copper-translocating P-type ATPases located in the trans-Golgi apparatus and believed to provide copper for important enzymes such as ceruloplasmin, tyrosinase, and peptidylglycine monooxygenase. Although a substantial amount... | ['Base Sequence', 'Binding Sites', 'Cation Transport Proteins', 'Cloning, Molecular', 'Copper', 'Copper Transport Proteins', 'DNA Primers', 'Dithiothreitol', 'Fourier Analysis', 'Glutathione', 'Humans', 'Ligands', 'Metallochaperones', 'Models, Molecular', 'Molecular Chaperones', 'Molecular Weight', 'Phosphines', 'Prote... | 12,686,548 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['E05.393.220'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D12.776.157.530.450.250.578', 'D12.776.543.585.450.250.578'], ['D13.695.578.424.450.275', 'D27.720.470.53... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reactivity of a dihydroboron species: synthesis of a hydroborenium complex and an expedient entry into stable thioxo- and selenoxo-boranes. | The reaction of a recently synthesized dihydroboron species complexed with bis(phosphinimino)amide, LBH2 (), (L = [N(Ph2PN(2,4,6-Me3C6H2))2](-)) with 3 equivalents of BH2Cl·SMe2 or one equivalent of BCl3 affords the first stable monohydridoborenium ion, [LBH](+)[HBCl3](-) () that is stable without a weakly coordinating... | ['Boron Compounds', 'Models, Molecular', 'Molecular Structure', 'Selenium', 'Sulfhydryl Compounds'] | 26,304,772 | [['D01.132', 'D02.203'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D01.268.185.850', 'D01.578.700'], ['D02.886.489']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluoroquinolone-resistant acute prostatitis requiring hospitalization after transrectal prostate biopsy: effect of previous fluoroquinolone use as prophylaxis or long-term treatment. | OBJECTIVES: This study aims to scrutinize the hospitalized patients with the diagnosis of acute prostatitis after transrectal ultrasound-guided biopsy of the prostate (TRUSBP) focusing their history of previous antibiotic use, clinical pictures, microbiologic features, and resistance patterns of the isolates.PATIENTS A... | ['Aged', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Antibiotic Prophylaxis', 'Biopsy', 'Carbapenems', 'Ceftriaxone', 'Ciprofloxacin', 'Drug Resistance, Multiple, Bacterial', 'Enterococcus', 'Escherichia coli', 'Escherichia coli Infections', 'Fluoroquinolones', 'Hospitalization', 'Humans', 'Length of Stay', 'Mal... | 21,547,465 | [['M01.060.116.100'], ['D27.505.954.122.085'], ['D27.505.954.122'], ['E02.319.162.150', 'E02.319.703.150'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D02.065.589.099.124', 'D03.633.100.300.124'], ['D02.065.589.099.249... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sex differences in energetic costs explain sexual dimorphism in the circadian rhythm modulation of the electrocommunication signal of the gymnotiform fish Brachyhypopomus pinnicaudatus. | To understand the evolution of sexually dimorphic communication signals, we must quantify their costs, including their energetic costs, the regulation of these costs, and the difference between the costs for the sexes. Here, we provide the first direct measurements of the relative energy expended on electric signals an... | ['Animal Communication', 'Animals', 'Circadian Rhythm', 'Electric Organ', 'Energy Metabolism', 'Female', 'Gymnotiformes', 'Male', 'Models, Biological', 'Oxygen Consumption', 'Sex Characteristics', 'Signal Transduction'] | 18,310,126 | [['F01.145.113.055'], ['B01.050'], ['G07.180.562.190'], ['A13.332'], ['G03.295'], ['B01.050.150.900.493.378.430'], ['E05.599.395'], ['G03.680'], ['G08.686.815'], ['G02.111.820', 'G04.835']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Glycine soja 14-3-3 protein GsGF14o participates in stomatal and root hair development and drought tolerance in Arabidopsis thaliana. | It is well established that 14-3-3 proteins are key regulators of multiple stress signal transduction cascades. However, the biological functions of soybean 14-3-3 proteins, especially in plant drought response, are not yet known. In this study, we characterized a Glycine soja 14-3-3 gene, GsGF14o, which is involved in... | ['14-3-3 Proteins', 'Adaptation, Physiological', 'Amino Acid Sequence', 'Arabidopsis', 'Droughts', 'Gene Expression Regulation, Plant', 'Gene Knockout Techniques', 'Genes, Plant', 'Germination', 'Molecular Sequence Data', 'Osmotic Pressure', 'Photosynthesis', 'Plant Roots', 'Plant Stomata', 'Plants, Genetically Modifie... | 24,272,249 | [['D12.644.360.024.050', 'D12.776.157.057.002', 'D12.776.476.024.050'], ['G07.025', 'G16.012.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['G05.308.375'], ['E05.393.335.750'], ['G05.360.340.024.340.393', 'G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Scirrhous colonic metastasis from ductal carcinoma of the breast: report of a case. | Metastasis of breast cancer to the colon is rare. We report a case of a 49-year-old female who presented with a stenotic tumor of the descending colon five years after treatment of breast cancer with mastectomy and pedicled transverse rectus abdominis musculocutaneous flap. Laparotomy showed a diffusely infiltrated tum... | ['Adenocarcinoma, Scirrhous', 'Breast Neoplasms', 'Carcinoma, Ductal', 'Colonic Neoplasms', 'Female', 'Humans', 'Middle Aged'] | 14,530,687 | [['C04.557.470.200.025.095'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232', 'C04.557.470.615.132'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.11... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Postprandial increase of cardiac output in patients with acute myocardial infarction. | The influence on the hemodynamics of oral and intravenous nourishment containing the same amount of calories in comparison to isotonic solution of sodium chloride was studied in 14 patients with acute myocardial infarction. Forty minutes after administration of nourishment, a 34% increase in cardiac index, rising from ... | ['Adult', 'Aged', 'Blood Glucose', 'Cardiac Output', 'Eating', 'Female', 'Hemodynamics', 'Humans', 'Lactates', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Oxygen Consumption'] | 3,583,456 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['E01.370.370.380.150', 'G09.330.380.124'], ['G07.203.650.283', 'G10.261.330'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Revealing the Usefulness of Aroma Networks to Explain Wine Aroma Properties: A Case Study of Portuguese Wines. | Wine aroma is the result of complex interactions between volatile compounds and non-volatile ones and individual perception phenomenon. In this work, an aroma network approach, that links volatile composition (chromatographic data) with its corresponding aroma descriptors was used to explain the wine aroma properties. ... | ['Chromatography, Gas', 'Fruit', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Norisoprenoids', 'Odorants', 'Portugal', 'Sulfhydryl Compounds', 'Vitis', 'Volatile Organic Compounds', 'Wine'] | 31,936,556 | [['E05.196.181.349'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.271.665.202.309', 'D02.455.426.392.368.367.379.249.375', 'D02.455.849.131.309'], ['G16.500.275.640', 'N06.230.480'], ['Z01.542.727'], ['D02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Change in the body temperature of healthy term infant over the first 72 hours of life. | OBJECTIVE: To determine the range of body temperature in a group of healthy Chinese term neonates over the first 72 hours of life and to assess the influence of body weight, gestational age and route of delivery.METHOD: All 200 consecutive cases of neonates delivered at our hospital from March to August 2001 were inclu... | ['Adaptation, Physiological', 'Age Factors', 'Birth Weight', 'Body Temperature', 'China', 'Female', 'Fever', 'Gestational Age', 'Humans', 'Hypothermia', 'Infant, Newborn', 'Male', 'Retrospective Studies'] | 14,994,443 | [['G07.025', 'G16.012.500'], ['N05.715.350.075', 'N06.850.490.250'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.600.875.374', 'G07.110'], ['Z01.252.474.164'], ['C23.888.119.344'], ['G07.345.500.325.235.968', 'G08.686... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Patient education using virtual reality increases knowledge and positive experience for breast cancer patients undergoing radiation therapy. | PURPOSE: Improved access to technology in the radiation therapy (RT) workforce education has resulted in opportunities for innovative patient education methods. This study investigated the impact of a newly developed education tool using the Virtual Environment for Radiotherapy Training (VERT) system on patients' RT kn... | ['Adult', 'Aged', 'Breast Neoplasms', 'Female', 'Humans', 'Knowledge', 'Middle Aged', 'Patient Education as Topic', 'Patient Reported Outcome Measures', 'Surveys and Questionnaires', 'Virtual Reality'] | 29,536,200 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.468'], ['M01.060.116.630'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E05.318.308.980.344.500', 'N03.349.380.210.750', 'N04.761.559.590.399.875', 'N05.425.210.500', 'N05.715.360.300.800.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Substrate and inhibitor specificity of kynurenine monooxygenase from Cytophaga hutchinsonii. | Kynurenine monooxygenase (KMO) is a potential drug target for treatment of neurodegenerative disorders such as Huntington's and Alzheimer's diseases. We have evaluated substituted kynurenines as substrates or inhibitors of KMO from Cytophaga hutchinsonii. Kynurenines substituted with a halogen at the 5-position are exc... | ['Cytophaga', 'Enzyme Inhibitors', 'Halogenation', 'Humans', 'Kinetics', 'Kynurenine', 'Kynurenine 3-Monooxygenase', 'Models, Molecular', 'Neurodegenerative Diseases', 'Substrate Specificity'] | 28,302,400 | [['B03.440.080.130.150', 'B03.440.400.425.300.150'], ['D27.505.519.389'], ['G02.111.323', 'G03.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D12.125.608'], ['D08.811.682.690.708.557'], ['E05.599.595'], ['C10.574'], ['G02.111.835']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Highly fluorescent reticulocytes after CD34+ peripheral blood progenitor cell transplantation. | Highly fluorescent reticulocyte (HFR) counts were evaluated in 13 consecutive patients affected by hematological malignancies and submitted to autologous selected CD34+ peripheral blood progenitor cell (PBPC) transplantation. Results were compared with a historical group of patients comparable for age, disease and cond... | ['Adult', 'Antigens, CD34', 'Female', 'Fluorescent Dyes', 'Graft Survival', 'Hematopoiesis', 'Hematopoietic Stem Cell Transplantation', 'Hodgkin Disease', 'Humans', 'Kinetics', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Multiple Myeloma', 'Reticulocyte Count', 'Reticulocytes', 'Transplantation, Autologous'] | 9,509,969 | [['M01.060.116'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G12.875.545.340'], ['G04.152.825', 'G09.188.343'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Gamma knife radiosurgery in neurosurgery]. | The gamma knife is a stereotactic radiosurgery device which allows well defined, deep seated brain tumors, or arteriovenous malformations having a diameter of less than 3 cm, to be treated in a single session under local anesthesia. This technique, which was first described over 40 years ago, has undergone major develo... | ['Anesthesia, Local', 'Arteriovenous Malformations', 'Brain Neoplasms', 'Humans', 'Neurosurgery', 'Radiosurgery'] | 9,522,414 | [['E03.155.086.231'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.425'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases. | The generation of genetically modified animals is important for both research and commercial purposes. The rat is an important model organism that until recently lacked efficient genetic engineering tools. Sequence-specific nucleases, such as ZFNs, TALE nucleases, and CRISPR/Cas9 have allowed the creation of rat knocko... | ['Animals', 'Base Sequence', 'Cells, Cultured', 'DNA Restriction Enzymes', 'Female', 'Gene Targeting', 'Genetic Engineering', 'Hypoxanthine Phosphoribosyltransferase', 'Male', 'Microinjections', 'Rats, Sprague-Dawley', 'Rats, Transgenic', 'Recombinant Proteins', 'Recombinational DNA Repair', 'Zygote'] | 24,989,021 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['E05.393.335'], ['E05.393.420'], ['D08.811.913.400.725.450'], ['E02.319.267.530.690', 'E05.591.570'], ['B01.050.150.900.649.313.992.635.505.700.750'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Flow cytometric sorting of paraffin-embedded tumor tissues considerably improves molecular genetic analysis. | The characterization of genetic aberrations in paraffin-embedded tumor material is impaired by contaminating normal cells. In the present study on the genetic causes of loss of HLA expression in diffuse large B-cell lymphoma (DLBCL), we compared the efficacy of microdissection with flow cytometric sorting of tumor cell... | ['Chromosome Aberrations', 'Chromosomes, Human, Pair 6', 'Dissection', 'Flow Cytometry', 'HLA Antigens', 'Humans', 'In Situ Hybridization, Fluorescence', 'Loss of Heterozygosity', 'Lymphoma, B-Cell', 'Lymphoma, Non-Hodgkin', 'Paraffin Embedding'] | 14,502,796 | [['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.325.330', 'G05.360.162.520.300.325.330'], ['E01.370.225.998.221', 'E04.221', 'E05.200.998.221'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microbiological investigation of retrodiscal tissues from patients with advanced internal derangement of the temporomandibular joint. | The aim of this study was to investigate the presence of bacteria in samples of retrodiscal tissues taken from patients suffering from advanced internal derangement of the temporomandibular joint (TMJ). 12 fresh retrodiscal tissue samples were taken from 12 consecutive patients who underwent unilateral TMJ discectomy f... | ['Adipose Tissue', 'Adult', 'Aged', 'Arthroplasty', 'Bacteria', 'Bacteriological Techniques', 'Coloring Agents', 'Debridement', 'Dissection', 'Female', 'Humans', 'Joint Dislocations', 'Male', 'Mandibular Condyle', 'Middle Aged', 'Temporal Bone', 'Temporomandibular Joint Disc', 'Temporomandibular Joint Disorders', 'Youn... | 22,244,078 | [['A10.165.114'], ['M01.060.116'], ['M01.060.116.100'], ['E04.555.110', 'E04.680.101'], ['B03'], ['E01.370.225.875.150', 'E05.200.875.150'], ['D27.720.233'], ['E04.176'], ['E01.370.225.998.221', 'E04.221', 'E05.200.998.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['A02.835.232.781... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A second-generation genetic linkage map for bighead carp (Aristichthys nobilis) based on microsatellite markers. | Bighead carp (Aristichthys nobilis) is an important aquaculture fish worldwide. Genetic linkage maps for the species were previously reported, but map resolution remained to be improved. In this study, a second-generation genetic linkage map was constructed for bighead carp through a pseudo-testcross strategy using int... | ['Animals', 'Chromosome Mapping', 'Crosses, Genetic', 'Cyprinidae', 'Female', 'Genetic Linkage', 'Genetic Markers', 'Genotype', 'Male', 'Microsatellite Repeats'] | 25,040,196 | [['B01.050'], ['E05.393.183'], ['E05.393.281'], ['B01.050.150.900.493.200.244'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['G05.380'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three-Dimensional Needle Shape Estimation in TRUS-Guided Prostate Brachytherapy Using 2-D Ultrasound Images. | In this paper, we propose an automated method to reconstruct the three-dimensional (3-D) needle shape during needle insertion procedures using only 2-D transverse ultrasound (US) images. Using a set of transverse US images, image processing and random sample consensus are used to locate the needle within each image and... | ['Brachytherapy', 'Humans', 'Male', 'Needles', 'Phantoms, Imaging', 'Prostate', 'Prostatic Neoplasms', 'Ultrasonography, Interventional'] | 26,372,660 | [['E02.815.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.612'], ['E07.671'], ['A05.360.444.575', 'A10.336.707'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E01.370.350.850.855', 'E04.502.890']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
BX795, a TBK1 inhibitor, exhibits antitumor activity in human oral squamous cell carcinoma through apoptosis induction and mitotic phase arrest. | TANK-binding kinase 1 (TBK1), a member of IêB Kinase (IKK)-related kinases, plays a role in regulating innate immunity, inflammation and oncogenic signaling. This study aims to investigate the role of BX795, an inhibitor of TBK1, in a panel of oral squamous cell carcinoma (OSCC) cell lines. The antitumor effects and me... | ['Antineoplastic Agents', 'Apoptosis', 'Autophagy', 'Carcinoma, Squamous Cell', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Humans', 'I-kappa B Kinase', 'Mitosis', 'Mouth Neoplasms', 'Phosphoproteins', 'Protein-Serine-Threonine Kinases', 'Proto-Oncogene Proteins c-akt', 'Pyrimi... | 26,607,461 | [['D27.505.954.248'], ['G04.146.954.035'], ['G04.011'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The antigen-binding capacity of serum IgG. An immunosorbent method applied to subtilisin as antigen. | A method for estimating the antigen-binding capacity of serum IgG is presented. A Sepharose anti-human IgG immunosorbent is incubated with test serum and washed. The antigen-binding capacity of the bound specific IgG is determined by incubation with purified, inactivated 125I-subtilisin. The method was applied tp the s... | ['Absorption', 'Antibody Specificity', 'Binding Sites, Antibody', 'Humans', 'Immunoglobulin G', 'In Vitro Techniques', 'Iodine Radioisotopes', 'Occupational Medicine', 'Subtilisins', 'Time Factors'] | 1,270,812 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['G12.100'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the effects of endothelin-1 and endothelin-3 on the rat stomach. | The effects of systemic administration of endothelin-1 and endothelin-3 on the susceptibility of the stomach to injury were compared in the anesthetized rat, as were their effects on gastric vascular tone, systemic blood pressure and hematocrit. When infused at concentrations in the 10(-7)-10(-6) M range, endothelin-1 ... | ['Animals', 'Blood Pressure', 'Endothelins', 'Endothelium, Vascular', 'Ethanol', 'Gastric Mucosa', 'Hematocrit', 'Male', 'Peptides', 'Rats', 'Rats, Inbred Strains', 'Stomach', 'Stomach Ulcer', 'Vasoconstriction'] | 2,673,803 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['A07.015.700.500', 'A10.272.491.355'], ['D02.033.375'], ['A03.556.875.875.440', 'A10.615.550.291'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.644'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Experiments with a biological material for the closure of incisional hernias. | A new preparation process was studied which should allow the implantation of collagen type I in its native structure in reconstructive surgery, in this special case for closure of incisional hernias. As experimental animals we used 30 female Lewis rats. A defect of the anterior abdominal wall measuring 3 cm X 4 cm was ... | ['Animals', 'Biocompatible Materials', 'Collagen', 'Female', 'Hernia, Ventral', 'Rats', 'Rats, Inbred Lew', 'Rats, Inbred Strains'] | 3,498,092 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C23.300.707.374.937'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.280', 'B01.050.150.900.649.313.992.635.505.700.400.280'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Intracranial hyperthermia through local photothermal heating with a fiberoptic microneedle device. | BACKGROUND AND OBJECTIVES: The fiberoptic microneedle device (FMD) seeks to leverage advantages of both laser-induced thermal therapy (LITT) and convection-enhanced delivery (CED) to increase volumetric dispersal of locally infused chemotherapeutics through sub-lethal photothermal heat generation. This study focused on... | ['Animals', 'Body Temperature', 'Cerebrum', 'Evans Blue', 'Hyperthermia, Induced', 'Lasers', 'Male', 'Necrosis', 'Needles', 'Optical Fibers', 'Rats', 'Rats, Inbred F344', 'Serum Albumin'] | 23,390,044 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['A08.186.211.200.885.287'], ['D02.172.560', 'D02.455.426.559.847.638.555.400', 'D02.886.645.600.080.050.650.300', 'D04.615.638.555.400'], ['E02.565'], ['E07.632.490', 'E07.710.520'], ['C23.550.717'], ['E07.612'], ['E07.632.750'], ['B01.050.150.900.649.313.992.635.505.7... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suction fixation system for stereotactic radiosurgery of intraocular malignancies. | We designed a suction fixation system for the radiosurgical treatment of intraocular malignancies with the Leksell gamma unit (gamma knife). OUr device consists of a circular suction chamber and an adjustable unit to be fixed to the Leksell stereotactic head frame. All components are made of plastic materials in order ... | ['Aged', 'Aged, 80 and over', 'Choroid Neoplasms', 'Ciliary Body', 'Equipment Design', 'Eye Neoplasms', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Melanoma', 'Neoplasms, Unknown Primary', 'Radiosurgery', 'Suction', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Uveal Neoplasms'] | 7,502,720 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.364.978.223', 'C11.319.494.198', 'C11.941.160.238', 'C11.941.855.198'], ['A09.371.060.160', 'A09.371.894.280'], ['E05.320'], ['C04.588.364', 'C11.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.557.465.625.650.510', 'C04.557... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Spontaneous True Gastroduodenal Artery Aneurysm Rupture after an Inguinal Hernia Operation. | Gastroduodenal artery aneurysms are a very rare subtype of visceral artery aneurysms. These are divided into two groups as true and pseudoaneurysms. Pseudogastroduodenal artery aneurysms, which develops secondary to pancreatitis, is seen more frequently, whereas the true aneurysms are much less common. Spontaneous rupt... | ['Abdominal Pain', 'Aneurysm', 'Aneurysm, Ruptured', 'Arteries', 'Duodenum', 'Embolization, Therapeutic', 'Endovascular Procedures', 'Hernia, Inguinal', 'Humans', 'Hypotension', 'Male', 'Middle Aged', 'Rupture, Spontaneous', 'Stomach', 'Treatment Outcome'] | 29,733,020 | [['C23.888.592.612.054', 'C23.888.821.030'], ['C14.907.055'], ['C14.907.055.185'], ['A07.015.114'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E02.520.360', 'E02.926.500'], ['E04.100.814.529', 'E04.502.382'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.514'], ['M01.060.116.630... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1. | The response to an innate immune challenge is conditioned by the time of day, but the molecular basis for this remains unclear. In myeloid cells, there is a temporal regulation to induction by lipopolysaccharide (LPS) of the proinflammatory microRNA miR-155 that correlates inversely with levels of BMAL1. BMAL1 in the m... | ["3' Untranslated Regions", 'ARNTL Transcription Factors', 'Adipose Tissue', 'Animals', 'Circadian Rhythm', 'Cytokines', 'Immunity, Innate', 'Macrophages', 'Mice', 'Mice, Knockout', 'MicroRNAs', 'NF-kappa B'] | 25,995,365 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D12.644.360.138.049', 'D12.776.260.103.249', 'D12.776.476.156.100', 'D12.776.930.125.249'], ['A10.165.114'], ['B01.050'], ['G07.180.562.190'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Neonatal chylothorax: aetiology, clinical course and efficacy of treatment]. | OBJECTIVES: To investigate the aetiology, clinical course and response to treatment of neonatal chylothorax.PATIENTS AND METHOD: Prospective study over a 2-year period in a neonatal intensive care unit of a tertiary university hospital. All newborns followed a predefined therapeutic protocol that included the sequentia... | ['Algorithms', 'Chylothorax', 'Combined Modality Therapy', 'Gastrointestinal Agents', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Injections, Intravenous', 'Octreotide', 'Prospective Studies', 'Suction'] | 18,358,132 | [['G17.035', 'L01.224.050'], ['C08.528.142'], ['E02.186'], ['D27.505.954.483'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D04.345.566.650', 'D12.644.641.650'], ['E05.318.372.500.750.625', 'N05.715.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Determination of 8-methoxypsoralen in mouse plasma by high performance liquid chromatography and its application to pharmacokinetic study]. | OBJECTIVE: To establish a high performance liquid chromatography (HPLC) method for the determination of 8-methoxypsoralen (8-MOP) in mouse plasma and apply it to a pharmacokinetic study of 8-MOP.METHODS: 8-MOP was separated on a Waters Symmetry18 column (250 mm ? 4.6 mm, 5 ìm) and determined by HPLC using isocratic elu... | ['Animals', 'Calibration', 'Chromatography, High Pressure Liquid', 'Male', 'Methoxsalen', 'Mice', 'Mice, Inbred ICR', 'Photosensitizing Agents', 'Plasma', 'Random Allocation'] | 30,337,737 | [['B01.050'], ['E05.978.155'], ['E05.196.181.400.300'], ['D03.383.663.283.446.794.500', 'D03.633.100.150.446.794.500', 'D03.633.300.770.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['D27.505.954.444.600', 'D27.505.954.600.710'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enhancement of LPS-induced microglial inflammation response via TLR4 under high glucose conditions. | BACKGROUND: Microglia activation mediated by toll-like receptor 4 (TLR4) plays an important role in neuroinflammation and postoperative cognitive dysfunction (POCD). Diabetes mellitus (DM) has been recently suggested as an independent risk factor for POCD. In this study, we investigate the potential exacerbation of the... | ['Animals', 'Cells, Cultured', 'Glucose', 'Inflammation', 'Interleukin-6', 'Janus Kinase 2', 'Lipopolysaccharides', 'Microglia', 'Rats', 'Rats, Sprague-Dawley', 'STAT3 Transcription Factor', 'Signal Transduction', 'Toll-Like Receptor 4', 'Tumor Necrosis Factor-alpha'] | 25,790,769 | [['B01.050'], ['A11.251'], ['D09.947.875.359.448'], ['C23.550.470'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D08.811.913.696.620.682.725.124.200', 'D12.776.476.393.200', 'D12.776.624.664.700.117'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunology in diabetic pregnancy: activated T cells in diabetic mothers and neonates. | Lymphocytes bearing surface antigens indicating early and full activation have been evaluated, in addition to T cell subsets, in blood samples from diabetic pregnant patients, neonates from diabetic mothers and control groups. The type of diabetes and the trimester of pregnancy were taken into account. Monoclonal antib... | ['Adult', 'Antigens, Surface', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Infant, Newborn', 'Lymphocyte Activation', 'Pregnancy', 'Pregnancy in Diabetics', 'T-Lymphocytes'] | 3,494,642 | [['M01.060.116'], ['D23.050.301'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['G08.686.784.769'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts. | Reactive oxygen species are an inevitable by-product of mitochondrial respiration. It has been estimated that between 0.4 and 4% of molecular oxygen is converted to the radical superoxide (O2*-) and this level is significantly influenced by the functional status of the mitochondria. It is well established that exogenou... | ['Animals', 'Apoptosis', 'Caspase 3', 'Caspases', 'Cell Division', 'Cell Transformation, Neoplastic', 'Cells, Cultured', 'Chromosomal Instability', 'Embryo, Mammalian', 'Female', 'Fibroblasts', 'Mice', 'Mitochondria', 'Oxidative Stress', 'Oxygen', 'Pregnancy', 'Superoxide Dismutase', 'Translocation, Genetic'] | 14,570,235 | [['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.144.220', 'G04.161.750.500'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accuracy and the effect of possible subject-based confounders of magnitude-based MRI for estimating hepatic proton density fat fraction in adults, using MR spectroscopy as reference. | PURPOSE: To determine the accuracy and the effect of possible subject-based confounders of magnitude-based magnetic resonance imaging (MRI) for estimating hepatic proton density fat fraction (PDFF) for different numbers of echoes in adults with known or suspected nonalcoholic fatty liver disease, using MR spectroscopy ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Humans', 'Liver', 'Magnetic Resonance Imaging', 'Magnetic Resonance Spectroscopy', 'Male', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Reproducibility of Results', 'Retrospective Studies', 'Young Adult'] | 26,201,284 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E01.370.350.825.500'], ['E05.196.867.519'], ['M01.060.116.630'], ['C06.552.241.519'], ['E05.318.370.725', 'E05.33... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Determination of the overall migration of chemicals from the plastic packaging into the aqueous models of food using the EU methods]. | Overall migration from food plastic packaging to aquatic food simulants (distilled water, 3% acetic acid) was determined according to the EU methods. Testing conditions (time and temperature) reflected normal use of tested food packaging. The overall migration studies using different food simulants (distilled water, 3%... | ['Acetic Acid', 'European Union', 'Food Additives', 'Food Contamination', 'Food Packaging', 'Food Preservation', 'Humans', 'Plastics', 'Poland', 'Sodium Chloride', 'Water'] | 15,307,610 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['I01.615.500.475'], ['D27.720.372.300', 'G07.203.300.514.500', 'J02.500.514.500'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['J01.576.423.200.375', 'J01.576.423.850.600', 'J01.576.761.400'], ['J01.576.423.850.700'], ['B01.050.150.900.64... | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Progressive resistive exercise in weaning high quadriplegics from the ventilator. | Acutely high level quadriplegics may experience neuromuscular respiratory insufficiency secondary to loss of use of intercostal and abdominal muscles as well as partial involvement of the phrenic nerve. Frequently, these patients will require mechanical ventilation in the initial stages of their treatment. These patien... | ['Adult', 'Breathing Exercises', 'Female', 'Humans', 'Male', 'Middle Aged', 'Quadriplegia', 'Respiration, Artificial', 'Respiratory Paralysis', 'Respiratory Therapy'] | 3,588,008 | [['M01.060.116'], ['E02.190.525.186', 'E02.779.474.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.622.760', 'C23.888.592.636.786'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['C08.618.846.812', 'C10.597.622.812', 'C23.888.592.636.812'], ['E02.880']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Foot-and-mouth disease virus protease 3C inhibits cellular transcription and mediates cleavage of histone H3. | Foot-and-mouth disease virus protease 3C is essential for the processing of the viral precursor polyprotein. It is shown here to also inhibit gene expression in baby hamster kidney cells after transient expression from transfected cDNA fragments. Protease 3C could not be detected by indirect immunofluorescence in contr... | ['Animals', 'Aphthovirus', 'Cricetinae', 'DNA', 'Fluorescent Antibody Technique', 'Gene Expression', 'Histones', 'Nucleic Acid Hybridization', 'Peptide Hydrolases', 'Precipitin Tests', 'Transcription, Genetic', 'Transfection'] | 2,154,880 | [['B01.050'], ['B04.820.578.750.070'], ['B01.050.150.900.649.313.992.635.075.250'], ['D13.444.308'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['G05.297'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomic considerations of anterior instrumentation of the thoracic spine. | Forty-seven dry thoracic specimens from T-3 to T-12 (470 thoracic vertebrae) were used to measure the dimensions of the vertebral body of the thoracic spine and to determine the relationship of the posterior angulation of screw placement to the spinal canal from different entrance points. Statistically significant diff... | ['Adult', 'Aged', 'Bone Screws', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sex Factors', 'Spinal Fusion', 'Thoracic Vertebrae'] | 9,193,696 | [['M01.060.116'], ['M01.060.116.100'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875'], ['E04.555.100.700'], ['A02.835.232.834.892']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Participation in Cancer Pharmacogenomic Studies: A Study of 8456 Patients Registered to Clinical Trials in the Cancer and Leukemia Group B (Alliance). | BACKGROUND: Clinically annotated specimens from cancer clinical trial participants offer an opportunity for discovery and validation of pharmacogenomic findings. The purpose of this observational study is to better understand patient/institution factors that may contribute to participation in the pharmacogenomic compon... | ['Adult', 'Aged', 'Aged, 80 and over', 'Clinical Trials, Phase III as Topic', 'Female', 'Healthcare Disparities', 'Humans', 'Leukemia', 'Male', 'Middle Aged', 'Multicenter Studies as Topic', 'Neoplasms', 'Odds Ratio', 'Patient Participation', 'Pharmacogenetics'] | 26,160,883 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.250.250.220', 'N05.715.360.330.250.250.220', 'N06.850.520.450.250.250.220'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['M01.060.116.630'], ['E05.318.372.658', 'N05.715.360.330.643',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Antinuclear antibodies (ANA) in inflammatory eye diseases]. | The occurrence of antinuclear antibodies was investigated in patients with chronic open-angle glaucoma, senile cataract and retinal detachment, using the indirect immunofluorescence technique. The values obtained were the same as those for a normal population. Additionally, the presence and titer levels of ANA were tes... | ['Antibodies, Antinuclear', 'Cataract', 'Eye Diseases', 'Fluorescent Antibody Technique', 'Glaucoma', 'Optic Disk', 'Optic Neuritis', 'Retinal Detachment', 'Uveitis'] | 6,999,225 | [['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['C11.510.245'], ['C11'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['C11.525.381'], ['A08.800.800.120.680.660', 'A09... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Action of fatty acids on the exocrine pancreatic secretion of the conscious rat: further evidence for a protein pancreatic inhibitory factor. | The existence of a delayed inhibition of the secretion of protein by the rat pancreas after intraduodenal injection of oleic acid has been confirmed. 1. This phenomenon is not dependent on the presence or absence of bile or pancreatic juice in the intestine. 2. The action of oleic acid is not a pathological phenomenon ... | ['Animals', 'Butyrates', 'Caprylates', 'Fatty Acids', 'Glucose', 'Male', 'Oleic Acids', 'Osmolar Concentration', 'Pancreas', 'Pancreatic Juice', 'Proteins', 'Rats', 'Secretory Rate', 'Triglycerides'] | 633,115 | [['B01.050'], ['D02.241.081.114', 'D10.251.400.143'], ['D02.241.081.222', 'D10.251.122'], ['D10.251'], ['D09.947.875.359.448'], ['D10.251.355.325.600'], ['G02.640'], ['A03.734'], ['A12.200.567'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700'], ['G03.857'], ['D10.351.801']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos. | We describe a new method for analyzing embryonic events dependent on a specific peptide recognition signal. A short, specific amino acid sequence in fibronectin has been implicated as a recognition site in fibronectin-mediated interactions. Fibroblast adhesion to fibronectin is competitively inhibited by certain synthe... | ['Animals', 'Cell Movement', 'Cells, Cultured', 'Chick Embryo', 'Fibronectins', 'Gastrula', 'Microscopy, Electron, Scanning', 'Neural Crest', 'Oligopeptides', 'Peptide Fragments', 'Pleurodeles', 'Quail'] | 6,490,722 | [['B01.050'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['A16.441'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A16.627'], ['D12.644.456'], ['D12.644.541'], ['B01.050.150.900.090.608.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical and roentgenologic changes after fibula resections: causes, differential diagnostic aspects, consequences]. | This study correlates the clinical and radiological development of twelve patients with resection of the fibula, with the results of experimental investigations, reporting on the loss of tension-banding and proportional weight-bearing after fibula resection. Five patients underwent segmental fibula resection because of... | ['Adolescent', 'Adult', 'Bone Neoplasms', 'Bone Resorption', 'Child', 'Female', 'Fibula', 'Follow-Up Studies', 'Fractures, Spontaneous', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiography', 'Tibia', 'Tibial Fractures', 'Weight-Bearing'] | 7,747,640 | [['M01.060.057'], ['M01.060.116'], ['C04.588.149', 'C05.116.231'], ['C05.116.264', 'G11.427.213.150'], ['M01.060.406'], ['A02.835.232.043.650.321'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Creativity, Cerebral Functional Heterogeneity, and "Oshikura Manju"]. | We discuss creativity as a product of cerebral functional heterogeneity. To understand the pathophysiology of acquired savant syndrome, we propose an "Oshikura Manju" hypothesis, named after a Japanese game for children. We also briefly explore the mechanisms of healing and nostalgia. | ['Cerebrum', 'Creativity', 'Humans'] | 29,887,529 | [['A08.186.211.200.885.287'], ['F01.752.264', 'F02.463.785.302'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Should the amputations of the great toe be replanted? | Seventeen great toes, amputated at the distal phalangeal to the level of the MTP joint, were replanted between 1990 and 1998, at Izmir Hand and Microsurgery Hospital. Replantation in five out of six complete amputations, and seven out of eleven incomplete amputations were successful, and the overall survival rate was 7... | ['Adolescent', 'Adult', 'Amputation, Traumatic', 'Biomechanical Phenomena', 'Case-Control Studies', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Gait', 'Hallux', 'Humans', 'Male', 'Middle Aged', 'Recovery of Function', 'Replantation', 'Retrospective Studies', 'Treatment Outcome'] | 10,966,366 | [['M01.060.057'], ['M01.060.116'], ['C26.062'], ['G01.154.090', 'G01.374.089'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.600.250', 'G11.427.410.568.900.750'], [... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prepartion of 16alpha-alkoxy and 16alpha-acyloxy derivatives of 21-chloro-17-acyloxy corticosteroids and determination of their vasoconstrictor activities in humans. | A number of number of 16alpha-alkoxy and 16alpha-acyloxy derivatives of 21-chloro-17-acyloxy corticosteroids have been prepared. The synthetic routes used were (a) reaction of the 16alpha,17-disubstituted 21-mesylate with lithium chloride and (b) reaction of the 16alpha-substituted 17,21-cyclic ortho ester with triphen... | ['Betamethasone Valerate', 'Humans', 'Pregnenediones', 'Skin', 'Steroids, Chlorinated', 'Vasoconstrictor Agents', 'Vasomotor System'] | 1,271,415 | [['D04.210.500.745.432.769.199.150', 'D04.210.500.908.093.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654'], ['A17.815'], ['D04.210.500.883'], ['D27.505.954.411.793'], ['A08.800.050.800.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of pain in temporomandibular disorders: the bio-psychosocial complexity. | Temporomandibular joint disorders (TMD) affect the joint, the masticatory muscles, or are expressed as a clinical combination of these two factors. The aims of this study were to: (i) identify the clinical and psychosocial factors that aid in the diagnosis and classification of acute and chronic TMD, (ii) determine spe... | ['Acute Disease', 'Adolescent', 'Adult', 'Chi-Square Distribution', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Psychological', 'Pain', 'Pain Measurement', 'Pilot Projects', 'Surveys and Questionnaires', 'Temporomandibular Joint Disorders'] | 15,975,765 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.695'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chaperone and protease functions of LON protease 2 modulate the peroxisomal transition and degradation with autophagy. | Balancing repair and degradation is essential for maintaining organellar and cellular homeostasis. Peroxisomes are ubiquitous organelles in eukaryotic cells that play pivotal roles in cell survival. However, the quality control mechanism used to maintain peroxisomes is unclear. Here, we demonstrate that LON protease 2 ... | ['Arabidopsis', 'Arabidopsis Proteins', 'Autophagy', 'Molecular Chaperones', 'Peroxisomes', 'Protease La'] | 24,492,254 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G04.011'], ['D12.776.580'], ['A11.284.430.214.190.500.585.600', 'A11.284.430.214.190.875.190.190.755.600'], ['D08.811.277.040.013.500.032.099.750', 'D08.811.277.040.025.024.032.099.750', 'D08.811.277.656.149.099.750', 'D08.811.277.656.300.065.750', 'D12.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychosis Following an Increase in Intrathecal Baclofen. | Baclofen is a commonly used medication to treat spasticity in neurologic disorders. In the traumatic brain injury (TBI) population, the intrathecal administration of baclofen is often preferred over oral administration due to cognitive side effects. Here we report on a case of a psychotic episode following an increase ... | ['Baclofen', 'Brain Injuries, Traumatic', 'Humans', 'Injections, Spinal', 'Male', 'Muscle Relaxants, Central', 'Muscle Spasticity', 'Psychotic Disorders'] | 27,346,089 | [['D02.241.081.114.500.350.100'], ['C10.228.140.199.444', 'C10.900.300.087.235', 'C26.915.300.200.194'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.580'], ['D27.505.696.510', 'D27.505.696.663.700.600', 'D27.505.954.427.525'], ['C05.651.512', 'C10.597.613.550.550', 'C23.888.592.608.550.550'], ['F... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Virological characteristics of hepatitis C virus infection in chronic hemodialysis patients: a cross-sectional study. | Detection of hepatitis C virus viremia (HCV RNA) in serum of hemodialysis (HD) patients is crucial for documenting ongoing infection because the clinical and epidemiological importance of anti-HCV positivity is not clear. HCV viremia was studied in 104 HD patients by reverse transcription polymerase chain reaction (RT ... | ['Cross-Sectional Studies', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Hepacivirus', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'Immunoblotting', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Prevalence', 'RNA, Viral', 'Renal Dialysis', 'Sensitivity and Specificity', 'Sero... | 7,554,533 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thermal epiphysiodesis performed with radio frequency in a porcine model. | BACKGROUND AND PURPOSE: Current techniques for epiphysiodesis involve opening of cortical windows; use of staples, screws, and tension devices; and fusion with curettes or drills. Complications may have serious consequences. There is a need for a more reliable, precise, and less traumatic procedure that overcomes the k... | ['Ablation Techniques', 'Animals', 'Disease Models, Animal', 'Epiphyses', 'Female', 'Growth Plate', 'Leg Length Inequality', 'Magnetic Resonance Imaging', 'Radiosurgery', 'Swine', 'Tibia'] | 25,036,720 | [['E04.014'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A02.835.232.251'], ['A02.835.232.251.352'], ['C05.116.099.655', 'C23.300.808'], ['E01.370.350.825.500'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['B01.050.150.900.649.313.500.880'], ['A02.835.232.043.650.883']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term Results of 180 Consecutive Patients with Abdominal Aortic Aneurysm Treated with the Endurant Stent Graft System. | BACKGROUND: Registry studies have shown that the Endurant stent graft is associated with low rates of all-cause and aneurysm-related mortality when used for the endovascular treatment of abdominal aortic aneurysm (AAA). However, many were limited by length of follow-up and all had a proportion of patients lost to follo... | ['Aged', 'Aged, 80 and over', 'Aortic Aneurysm, Abdominal', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Databases, Factual', 'Endovascular Procedures', 'Female', 'Humans', 'Male', 'Postoperative Complications', 'Prospective Studies', 'Prosthesis Design', 'Risk Factors', 'Stents', 'Time Factors',... | 32,205,240 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['E05.318.372.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Seasonal variation in paired maternal-newborn serum 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D concentrations in Israel. | Seasonal changes were observed in the vitamin D status of mothers and their newly born infants in sunny Israel. Maternal and newborn serum levels of 25-hydroxyvitamin D (25-OHD) were lower (less than 0.01) in March-April (n = 45 pairs), than in September-October (n = 33 pairs). Parallel seasonal changes were also found... | ['24,25-Dihydroxyvitamin D 3', 'Adult', 'Calcifediol', 'Dihydroxycholecalciferols', 'Female', 'Humans', 'Infant, Newborn', 'Israel', 'Pregnancy', 'Seasons', 'Vitamin D'] | 3,497,905 | [['D04.210.500.247.222.159.478.387.400', 'D04.210.500.247.808.146.478.387.400', 'D04.210.500.812.768.196.478.387.400', 'D10.570.938.146.478.387.400'], ['M01.060.116'], ['D04.210.500.247.222.159.478.250', 'D04.210.500.247.808.146.478.250', 'D04.210.500.812.768.196.478.250', 'D10.570.938.146.478.250'], ['D04.210.500.247.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Changes in limb dynamics during the practice of rapid arm movements. | In our study we examined Bernstein's hypothesis that practice alters the motor coordination among the muscular and passive joint moments. In particular, we conducted dynamical analyses of a human multisegmental movement during the practice of a task involving the upper extremity. Seven male human volunteers performed m... | ['Action Potentials', 'Adult', 'Arm', 'Electromyography', 'Humans', 'Male', 'Movement', 'Muscles', 'Physical Education and Training', 'Time Factors'] | 2,613,716 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['A01.378.800.075'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['A02.633', 'A10.690'], ['I02.233.543'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The complete genome of a viable archaeum isolated from 123-million-year-old rock salt. | Live microbes have been isolated from rock salt up to Permian age. Only obligatory cellular functions can be performed in halite-buried cells. Consequently, their genomic sequences are likely to remain virtually unchanged. However, the available sequence information from these organisms is scarce and consists of mainly... | ['Base Sequence', 'China', 'Clustered Regularly Interspaced Short Palindromic Repeats', 'DNA, Archaeal', 'Genome, Archaeal', 'Halobacterium', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Sodium Chloride'] | 26,628,271 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.252.474.164'], ['G02.111.570.080.708.800.325.500', 'G05.360.080.708.800.325.500', 'G05.360.340.024.850.069'], ['D13.444.308.180'], ['G05.360.340.358.050'], ['B02.200.400.400.410'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['E05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
SO2-* electron transfer ion/ion reactions with disulfide linked polypeptide ions. | Multiply-charged peptide cations comprised of two polypeptide chains (designated A and B) bound via a disulfide linkage have been reacted with SO2-* in an electrodynamic ion trap mass spectrometer. These reactions proceed through both proton transfer (without dissociation) and electron transfer (with and without dissoc... | ['Amino Acid Sequence', 'Animals', 'Cattle', 'Disulfides', 'Electrons', 'Ions', 'Lactalbumin', 'Molecular Sequence Data', 'Oxytocin', 'Peptides', 'Somatostatin', 'Spectrometry, Mass, Electrospray Ionization', 'Sulfites'] | 15,914,021 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['G01.249.335', 'G01.358.500.750'], ['D01.248.497'], ['D12.776.034.398', 'D12.776.256.159.750.816.250'], ['L01.453.245.667'], ['D06.472.699.631.692.43... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[A Case of Huge Advanced Neuroendocrine Carcinoma of the Transverse Colon Resected Successfully]. | The patient, 49-year-old woman, who was referred to our hospital in August 2016 because of left abdominal pain. The abdominal CT scan showed a large tumor, over 10 cm dimeter at splenic flexure of the transverse colon, and colonoscopy detected transvers colon cancer(por, cT4b, cN1, M0, cStage III A). There was no dista... | ['Carcinoma, Neuroendocrine', 'Colectomy', 'Colon, Transverse', 'Colonic Neoplasms', 'Female', 'Humans', 'Middle Aged'] | 29,394,710 | [['C04.557.465.625.650.240', 'C04.557.470.200.025.370', 'C04.557.580.625.650.240'], ['E04.210.219'], ['A03.556.124.526.356.834', 'A03.556.249.249.356.834'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Practical approach to the evaluation of industrial wastewater treatment by the application of advanced microbiological techniques. | In cork industry, the operation of boiling raw cork generates large volumes of wastewater named Cork Boiling Wastewater (CBW). The main characteristics are the low biodegradability and medium to low acute toxicity, resulting in the necessity of designing advanced biological treatments by possible conventional activated... | ['Bacteria', 'Biodegradation, Environmental', 'Metagenomics', 'Oxidation-Reduction', 'Real-Time Polymerase Chain Reaction', 'Sewage', 'Waste Disposal, Fluid', 'Waste Water'] | 30,265,875 | [['B03'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['H01.158.273.343.350.261'], ['G02.700', 'G03.295.531'], ['E05.393.620.500.706'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.710.865']] | ['Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers. | Toll-like receptor (TLR) signaling is one of the most important signaling cascades of the innate immune system of vertebrates. Studies in invertebrates have focused on the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans, and there is little information regarding the evolutionary origin and anc... | ['Animals', 'Anti-Bacterial Agents', 'Base Sequence', 'Colony Count, Microbial', 'Disease Susceptibility', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Gene Knockdown Techniques', 'Hydra', 'JNK Mitogen-Activated Protein Kinases', 'Myeloid Differentiation Factor 88', 'Oligonucleotide Array Sequence Analys... | 23,112,184 | [['B01.050'], ['D27.505.954.122.085'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E01.370.225.875.220', 'E05.200.875.220'], ['C23.550.291.687', 'G07.100.250'], ['E05.393.332'], ['G05.308'], ['E05.393.335.500'], ['B01.050.500.308.485.400'], ['D08.811.913.696.620.682.700.567.374', 'D12.644.360.450.340',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intracellular location of mycoplasmas in cultured cells demonstrated by immunocytochemistry and electron microscopy. | Mycoplasma fermentans (strain 'incognitus') was incubated with HeLa cells for up to 96 h. After 24 h, mycoplasma organisms were demonstrated intracellularly by immunocytochemistry using mule anti-M. fermentans antiserum and gold labelling on ultrathin sections of both Lowicryl K4M and Araldite-embedded HeLa cells, the ... | ['HeLa Cells', 'Humans', 'Immunohistochemistry', 'Microscopy, Electron', 'Mycoplasma', 'Mycoplasma fermentans'] | 1,768,615 | [['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.5... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Computerized Dead-Space Volume Measurement of Face Masks Applied to Simulated Faces. | BACKGROUND: The dead-space volume (VD) of face masks for metered-dose inhaler treatments is particularly important in infants and young children with asthma, who have relatively low tidal volumes. Data about VD have been traditionally obtained from water displacement measurements, in which masks are held against a flat... | ['Administration, Inhalation', 'Aerosols', 'Bronchodilator Agents', 'Child, Preschool', 'Computer Simulation', 'Equipment Design', 'Face', 'Humans', 'Imaging, Three-Dimensional', 'Infant', 'Infant, Newborn', 'Masks', 'Metered Dose Inhalers', 'Respiratory Dead Space', 'Respiratory Therapy', 'Tidal Volume'] | 25,944,944 | [['E02.319.267.050'], ['D20.280.055', 'D26.255.165.055'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['M01.060.406.448'], ['L01.224.160'], ['E05.320'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.703'], ['M01.060.703.520'], ['E07.325.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Redesign of thoracic surgical services within a cancer network-using an oncology focus to inform change. | Thoracic surgical services for one cancer network in London are based at one NHS Trust. Approximately 80% of the surgery performed in the period January-December 2003 was for the diagnosis, palliation or treatment of cancer. The range of different patient groups and needs is very wide, ranging from teenagers undergoing... | ['Adolescent', 'Adult', 'Aged', 'Cancer Care Facilities', 'Humans', 'London', 'Lung Neoplasms', 'Middle Aged', 'Organizational Case Studies', 'Organizational Innovation', 'Program Evaluation', 'State Medicine', 'Thoracic Surgery'] | 15,774,343 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N02.278.421.556.070'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.433.553', 'Z01.542.363.300.553'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['N03.349.380.710', 'N05.715.360.455'], ['N04.452.610'], ['E05.337.820', '... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Malignant fibrous histiocytoma of the pharynx. | Malignant fibrous histiocytoma (MFH) is the most common soft-tissue sarcoma of late adult life, but is relatively uncommon in the head and neck region. That region has been reported to be the origin of malignant fibrous histiocytoma in 3-10% of cases. Only one case of the tumor occurring in the pharynx has been reporte... | ['Histiocytoma, Benign Fibrous', 'Humans', 'Male', 'Middle Aged', 'Pharyngeal Neoplasms', 'Tomography, X-Ray Computed'] | 12,642,957 | [['C04.557.450.565.590.425.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.443.665.710', 'C07.550.745', 'C09.647.710', 'C09.775.549'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
TideHunter: efficient and sensitive tandem repeat detection from noisy long-reads using seed-and-chain. | MOTIVATION: Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) sequencing technologies can produce long-reads up to tens of kilobases, but with high error rates. In order to reduce sequencing error, Rolling Circle Amplification (RCA) has been used to improve library preparation by amplifying circulariz... | ['High-Throughput Nucleotide Sequencing', 'Nanopores', 'Sequence Analysis, DNA', 'Software', 'Tandem Repeat Sequences'] | 31,510,677 | [['E05.393.760.319'], ['J01.637.512.650'], ['E05.393.760.700'], ['L01.224.900'], ['G02.111.570.080.708.800', 'G05.360.080.708.800', 'G05.360.340.024.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Multimodality imaging in Europe: a survey by the European Association of Nuclear Medicine (EANM) and the European Society of Radiology (ESR). | PURPOSE: Multimodality imaging represents an area of rapid growth with important professional implication for both nuclear medicine physicians and radiologists throughout Europe. As a preliminary step for future action aimed at improving the quality and accessibility of PET/SPECT/CT multimodality imaging practice in Eu... | ['Europe', 'Health Care Surveys', 'Nuclear Medicine', "Practice Patterns, Physicians'", 'Subtraction Technique', 'Tomography, Emission-Computed'] | 19,915,843 | [['Z01.542'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['H02.403.740.500'], ['N04.590.374.577', 'N05.300.625'], ['E01.370.350.760'], ['E01.370.350.350.800', 'E01.370.350.600.350.800', 'E01.370.350.710.800', 'E01.370.350.825.800', 'E01.370.384.730.8... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Pathogenetic changes in the lung bud of mutant rats with heritable pulmonary lobation anomalies. | The present study aimed at investigating pathogenesis of pulmonary lobation anomalies in fpl/fpl mutant rats. Day 12-15 embryos were first examined for pulmonary lobation. Lung serial sections were then made and examined for bronchial branching and distribution of extracellular matrices (ECMs). The lung buds of both fp... | ['Animals', 'Female', 'Lung', 'Male', 'Microscopy, Electron, Scanning', 'Rats', 'Rats, Mutant Strains'] | 7,871,481 | [['B01.050'], ['A04.411'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.550']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of reductive ventricular osmotherapy in a swine model of traumatic brain injury. | BACKGROUND: The presence of osmotic gradients in the development of cerebral edema and the effectiveness of osmotherapy are well recognized. A modification of ventriculostomy catheters described in this article provides a method of osmotherapy that is not currently available. The reductive ventricular osmotherapy (RVOT... | ['Animals', 'Brain Edema', 'Brain Injuries', 'Catheters', 'Disease Models, Animal', 'Osmolar Concentration', 'Swine', 'Ventriculostomy'] | 21,826,032 | [['B01.050'], ['C10.228.140.187'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E07.132'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G02.640'], ['B01.050.150.900.649.313.500.880'], ['E04.035.188.957', 'E04.525.170.860']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells. | Although Tamoxifen (TAM) is one of the most widely used drugs in managing breast cancer, many women still relapse after long-term therapy. Caffeic acid phenethyl ester (CAPE) is a polyphenolic compound present in many medicinal plants and in propolis. The present study examined the effect of CAPE on TAM cytotoxicity in... | ['Antineoplastic Combined Chemotherapy Protocols', 'Apoptosis Regulatory Proteins', 'Beclin-1', 'Breast Neoplasms', 'Caffeic Acids', 'Female', 'Humans', 'MCF-7 Cells', 'Membrane Proteins', 'Microtubule-Associated Proteins', 'Phenylethyl Alcohol', 'Proto-Oncogene Proteins c-bcl-2', 'Tamoxifen'] | 26,697,130 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.644.360.075.335', 'D12.776.094.500', 'D12.776.476.075.335'], ['C04.588.180', 'C17.800.090.500'], ['D02.241.223.200.054'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.630'], ['D12.776.543'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A neglected case of macrodystrophia lipomatosa of the foot in an elderly man. | Macrodystrophia lipomatosa is a rare disorder characterized by three-dimensional enlargement of one or more fingers or toes with predominantly fibroadipose tissue. Radiographically, it appears as hypertrophy of soft tissues and bones. The pathologic findings are infiltration and hypertrophy of adipose tissue in subcuta... | ['Aged', 'Fatal Outcome', 'Foot Deformities, Congenital', 'Humans', 'Lipomatosis', 'Male', 'Middle Aged', 'Radiography', 'Toes', 'Treatment Refusal'] | 16,166,469 | [['M01.060.116.100'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C05.330.495', 'C05.660.585.512.380', 'C16.131.621.585.512.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.463', 'C18.452.584.718'], ['M01.060.116.630'], ['E01.370.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The relation between smoking-specific parenting and smoking trajectories of adolescents: how are changes in parenting related to changes in smoking? | In this study, we tested to what extent smoking-specific parenting and changes in parenting are related to adolescents' smoking trajectories. Data were used from a four-wave prospective study including 428 adolescents (aged M = 15.2; SD = 0.60). Latent Class Growth Analyses were conducted to identify trajectories. Mult... | ['Adolescent', 'Adolescent Behavior', 'Female', 'Humans', 'Interviews as Topic', 'Logistic Models', 'Male', 'Models, Theoretical', 'Netherlands', 'Parenting', 'Prospective Studies', 'Smoking'] | 20,437,293 | [['M01.060.057'], ['F01.145.022'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450',... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
New considerations on pathways involved in acute traumatic coagulopathy: the thrombin generation paradox. | Background: An acute traumatic coagulopathy (ATC) is observed in about one third of severely traumatized patients. This early, specific, and endogenous disorder is triggered by the association of trauma and hemorrhage. The early phase of this condition is characterized by the expression of a bleeding phenotype leading ... | ['Animals', 'Arterial Pressure', 'Disease Models, Animal', 'Disseminated Intravascular Coagulation', 'Fibrinogen', 'Lactic Acid', 'Potassium', 'Prothrombin', 'Prothrombin Time', 'Rats', 'Rats, Sprague-Dawley', 'Thrombin', 'Wounds and Injuries'] | 31,857,822 | [['B01.050'], ['G09.330.380.076.347'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C15.378.100.220', 'C15.378.463.250', 'C15.378.925.220'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D02.241.511.459.450'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of rearing method on the storage of fats by adipose tissue in sheep]. | Adipocyte synthesis de novo and lipoprotein lipase activity have been used simultaneously to measure the lipogenic activity of adipose tissue in sheep. Acetate and glucose were used as precursors of fatty acid synthesis. The sheep were raised either outdoors or in a sheepfold. They were slaughtered by lots at mean weig... | ['Acetates', 'Adipose Tissue', 'Animals', 'Environment', 'Fatty Acids', 'Glucose', 'Lipids', 'Lipoprotein Lipase', 'Male', 'Sheep'] | 6,648,030 | [['D02.241.081.018', 'D10.251.400.045'], ['A10.165.114'], ['B01.050'], ['G16.500.275', 'N06.230'], ['D10.251'], ['D09.947.875.359.448'], ['D10'], ['D08.811.277.352.100.430'], ['B01.050.150.900.649.313.500.380.791']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Functional studies with anti-CD3 heavy chain isotype switch-variant monoclonal antibodies. Accessory cell-independent induction of interleukin 2 responsiveness in T cells by epsilon-anti-CD3. | A series of heavy chain isotype switch-variant anti-CD3 monoclonal antibodies (mAb) was used to study the proliferation requirements of purified T cells. None of the variant antibodies was able by itself to induce proliferation. In the presence of exogenous interleukin 2 (IL-2) strong mitogenesis was observed upon stim... | ['Antibodies, Monoclonal', 'Antibody Affinity', 'Antigens, Differentiation, T-Lymphocyte', 'Calcium', 'Endocytosis', 'Humans', 'Immunoglobulin E', 'Immunoglobulin Fab Fragments', 'Immunoglobulin Isotypes', 'Immunologic Capping', 'Lymphocyte Activation', 'Receptors, Immunologic', 'Receptors, Interleukin-2', 'T-Lymphocyt... | 3,117,878 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.040', 'G12.122.125'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.312',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Restimulation properties of human alloreactive cloned T-cell lines. Dissection of HLA-D-region alleles in population studies and in family segregation analysis. | Alloactivated human lymphocytes were cloned by limiting dilution. After 1 month in culture with T-cell growth factor several clones incorporated tritiated thymidine when stimulated with the appropriate allogeneic cells. Specificity of restimulation of two primed lymphocyte clones, designated 12-2 and 12-8, was studied ... | ['Alleles', 'Clone Cells', 'Female', 'HLA-D Antigens', 'Histocompatibility Testing', 'Humans', 'Lymphocyte Activation', 'Male', 'Pedigree', 'T-Lymphocytes'] | 6,242,886 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of putrescine in cell proliferation in a colon carcinoma cell line. | OBJECTIVES: Putrescine, the precursor for higher polyamine biosynthesis, is necessary for cell growth in mammals. Ornithine decarboxylase (ODC) activity and polyamine production are increased in neoplastic cells. Using colon cancer cell line derived from a tumor with high metastatic potential (CT-26), our objective was... | ['Adenocarcinoma', 'Cell Division', 'Chromatography, High Pressure Liquid', 'Colonic Neoplasms', 'Dose-Response Relationship, Drug', 'Humans', 'Ornithine Decarboxylase', 'Polyamines', 'Putrescine', 'Time Factors', 'Tumor Cells, Cultured'] | 11,744,344 | [['C04.557.470.200.025'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E05.196.181.400.300'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of polyphenols and lipids from Pennisetum glaucum grains on T-cell activation: modulation of Ca(2+) and ERK1/ERK2 signaling. | BACKGROUND: Pearl millet (PM), i.e., Pennisetum glaucum, is widely grown in Africa and known for its anti-oxidant and anti-hyperlipidemic properties.METHODS: The P. glaucum grains were obtained from the region of Ouled A?ssa (South of Algeria). We assessed the effects of phenolic compounds and lipids, extracted from se... | ['Animals', 'Antioxidants', 'Calcium', 'Cell Proliferation', 'Edible Grain', 'Extracellular Signal-Regulated MAP Kinases', 'Hypolipidemic Agents', 'Lipids', 'Lymphocyte Activation', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Pennisetum', 'Plant Extracts', 'Polyphenols', 'Rats', 'Seeds'... | 26,627,682 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.161.750', 'G07.345.249.410.750'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The role of NMR imaging in the assessment of multiple sclerosis and isolated neurological lesions. A quantitative study. | The form and distribution of MRI abnormalities in 114 patients with clinically definite multiple sclerosis (MS) have been compared with observations on 53 apparently healthy individuals, 129 patients with isolated focal neurological lesions with which MS often presents (51 patients with optic neuritis, 44 with isolated... | ['Adolescent', 'Adult', 'Brain', 'Brain Stem', 'Central Nervous System Diseases', 'Cerebellum', 'Cerebrovascular Disorders', 'Evoked Potentials, Auditory', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Multiple Sclerosis', 'Nerve Degeneration', 'Nervous System Diseases', 'Optic Neuritis', 'Spinal Co... | 3,427,402 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['A08.186.211.132'], ['C10.228'], ['A08.186.211.132.810.428.200'], ['C10.228.140.300', 'C14.907.253'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.1... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enantiomeric separation of methamphetamine and related analogs by capillary zone electrophoresis: intelligence study in routine methamphetamine seizures. | A method for simultaneous enantiomeric separation of ephedrine, pseudoephedrine, and methamphetamine (MA) in a single run by simple capillary zone electrophoresis (CZE) with beta-cyclodextrin as a chiral selector is described. The effects of the buffer pH, phosphate concentration, beta-cyclodextrin concentration, volta... | ['Cyclodextrins', 'Electrophoresis, Capillary', 'Forensic Medicine', 'Humans', 'Illicit Drugs', 'Indicators and Reagents', 'Methamphetamine', 'Spectrophotometry, Ultraviolet'] | 12,455,645 | [['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['E05.196.401.190', 'E05.301.300.190'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['D27.720.470.410'], ['D02.092.471.683.152.619'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Growth in bone strength, body size, and muscle size in a juvenile longitudinal sample. | A longitudinal sample of 20 subjects, measured an average of 34 to 35 times each at approximately 6-month intervals from near birth through late adolescence, was used to investigate relationships between body size, muscle size, and bone structural development. The section modulus, an index of bone strength, was calcula... | ['Adolescent', 'Body Constitution', 'Body Weight', 'Bone Development', 'Child', 'Child, Preschool', 'Female', 'Femur', 'Humans', 'Humerus', 'Infant', 'Longitudinal Studies', 'Male', 'Muscle, Skeletal', 'Radiography', 'Weight-Bearing'] | 13,678,772 | [['M01.060.057'], ['E01.370.600.115', 'G07.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['M01.060.406'], ['M01.060.406.448'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Behavioral treatment of childhood social phobia. | Sixty-seven children (ages 8 and 12) with social phobia were randomized to either a behavioral treatment program designed to enhance social skills and decrease social anxiety (Social Effectiveness Therapy for Children, SET-C) or an active, but nonspecific intervention (Testbusters). Children treated with SET-C were sig... | ['Behavior Therapy', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Phobic Disorders', 'Social Behavior', 'Treatment Outcome'] | 11,142,541 | [['F04.754.137'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.725'], ['F01.145.813'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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