Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Long-term use of a high-complex-carbohydrate, high-fiber, low-fat diet and exercise in the treatment of NIDDM patients. | The purpose of this study was to assess the long-term effects of a high-complex-carbohydrate, high-fiber, low-fat diet and exercise on 69 NIDDM patients. During the initial 26-day program, fasting glucose was reduced from 179.5 +/- 10.6 to 133.5 +/- 4.0 mg/dl. This decrease in fasting glucose was achieved along with th... | ['Adult', 'Aged', 'Blood Glucose', 'Cholesterol', 'Diabetes Mellitus', 'Diet, Diabetic', 'Dietary Carbohydrates', 'Dietary Fats', 'Dietary Fiber', 'Energy Intake', 'Exercise Therapy', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Time Factors', 'Triglycerides'] | 6,307,614 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C18.452.394.750', 'C19.246'], ['E02.642.249.240', 'G07.203.650.240.240'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
The effect of high-tech AAC system position on the joint attention of infants without disabilities. | Joint attention is critical for language development in children. Children with complex communication needs have additional challenges in managing their joint attention, and there is minimal information on how to reduce these demands. Sixteen infants without disabilities and their caregivers participated in a within-su... | ['Aging', 'Analysis of Variance', 'Attention', 'Caregivers', 'Communication Aids for Disabled', 'Female', 'Humans', 'Infant', 'Interpersonal Relations', 'Male', 'Psychological Tests', 'Reading', 'Reproducibility of Results', 'Time Factors'] | 19,639,478 | [['G07.345.124'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.104.214'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E07.796.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.829.401'], ['F04.711'], ['L01.559.423.557'], ['E05.318.370.725', 'E05.337.851'... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Repeatability of primary selective laser trabeculoplasty in patients with primary open-angle glaucoma. | To determine if primary selective laser trabeculoplasty (SLT) can be repeated with clinical benefit in patients with primary open-angle glaucoma (POAG). Forty-two eyes of 42 patients with POAG were studied. All patients underwent primary SLT treatment of 40-50 shots to the trabecular meshwork over 360°. The treatment r... | ['Aged', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Laser Therapy', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Retrospective Studies', 'Trabecular Meshwork', 'Trabeculectomy'] | 23,371,484 | [['M01.060.116.100'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500'... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Underascertainment of child abuse mortality in the United States. | CONTEXT: Mortality figures in the United States are believed to underestimate the incidence of fatal child abuse.OBJECTIVES: To describe the true incidence of fatal child abuse, determine the proportion of child abuse deaths missed by the vital records system, and provide estimates of the extent of abuse homicides in y... | ['African Americans', 'Child', 'Child Abuse', 'Child, Preschool', 'Coroners and Medical Examiners', 'Data Collection', 'European Continental Ancestry Group', 'Female', 'Health Surveys', 'Homicide', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'North Carolina', 'Regression Analysis', 'Retrospective Studie... | 10,442,662 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.060.406.448'], ['M01.526.485.230', 'N02.360.230'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['M01.686.508.400'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N0... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Uptake and metabolism of thyroid hormones by cultured monkey hepatocarcinoma cells. Effects of potassium cyanide and dinitrophenol. | Cultured monkey hepatocarcinoma cell (NCLP-6E) were used to investigate the uptake and metabolism of thyroid hormones. Intracellular accumulation was shown by the failure to acutely release hormone from cells subsequently exposed to serum proteins, and by the metabolic trnasformation of the hormones to deiodinated prod... | ['Animals', 'Biological Transport, Active', 'Cell Line', 'Cyanides', 'Dinitrophenols', 'Liver', 'Liver Neoplasms, Experimental', 'Thyroid Hormones', 'Thyroxine', 'Triiodothyronine'] | 567,494 | [['B01.050'], ['G03.143.310'], ['A11.251.210'], ['D01.248.497.158.291', 'D01.625.400.100'], ['D02.455.426.559.389.657.566.304', 'D02.640.743.304'], ['A03.620'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['D06.472.931'], ['D06.472.931.812', 'D12.125.072.050.767'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contrast sensitivity after wave front-guided LASIK. | PURPOSE: To compare the effects on contrast sensitivity of wave front-guided (WFG) versus standard LASIK.DESIGN: Prospective, nonrandomized, comparative clinical study.PARTICIPANTS: Twenty-four eyes of 13 consecutive patients (mean age, 25.2+/-8.4 years; spherical equivalent, -0.5 to -4.25 diopters [D]) treated with WF... | ['Adult', 'Contrast Sensitivity', 'Cornea', 'Humans', 'Keratomileusis, Laser In Situ', 'Myopia', 'Prospective Studies'] | 15,019,318 | [['M01.060.116'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['A09.371.060.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594.480.750', 'E04.014.520.480.750', 'E04.378.500.750', 'E04.540.825.437.374'], ['C11.744.636'], ['E05.31... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Covalent modification of nitrogenase MoFe protein by ADP. | MgADP- reacted with the nitrogenase molybdenum-iron (MoFe) protein of Klebsiella pneumoniae (Kp1) over a period of 2 h to yield a stable, catalytically active conjugate. The isolated protein exhibited a new, broad 31P NMR resonance at -1 p.p.m. lacking phosphorus J coupling. The adenine ring of [8-14C]ADP remained asso... | ['Adenosine Diphosphate', 'Klebsiella pneumoniae', 'Magnetic Resonance Spectroscopy', 'Molybdoferredoxin', 'Nitrogenase', 'Protein Binding'] | 9,148,743 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['E05.196.867.519'], ['D08.811.682.647.550', 'D12.776.097.350.450', 'D12.776.157.427.374.375.275.450', 'D12.776.556.579.374.375.275.450'], ['D08.811.682.647'], ['G02.111.679', 'G03.808... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of transportation in the persuasion process: cognitive and affective responses to antidrug narratives. | This study examined transportation effects of first- and third-person narratives as well as the role of transportation in the persuasion process. In particular, the authors evaluated the role of transportation in affecting cognitive and affective responses. Last, they addressed the relation between (a) cognitive and af... | ['Adult', 'Affect', 'Cocaine-Related Disorders', 'Cognition', 'Female', 'Health Promotion', 'Humans', 'Male', 'Middle Aged', 'Narration', 'Persuasive Communication', 'Program Evaluation', 'Transportation', 'United Kingdom', 'Young Adult'] | 22,475,073 | [['M01.060.116'], ['F01.470.047'], ['C25.775.300', 'F03.900.300'], ['F02.463.188'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.502', 'F01.145.209.459', 'L01.399.250.660', 'N05.715.360.300.480', 'N06.850.520.308.502'], ['L01.143.762'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Geogr... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Pancreatic alkaline phosphatase and a tumour variant. | Alkaline phosphatase has been extracted from human pancreas with n-butanol and has been shown to have distinctive isoenzyme characteristics when compared with the enzymes of small intestine and of normal serum. The enzyme has been demonstrated histochemically in a carcinoma of the pancreas and also in an islet cell tum... | ['Adenocarcinoma', 'Adenoma, Islet Cell', 'Alkaline Phosphatase', 'Bone and Bones', 'Carcinoma', 'Electrophoresis, Disc', 'Histocytochemistry', 'Hot Temperature', 'Humans', 'Intestine, Small', 'Isoenzymes', 'Liver', 'Pancreas', 'Pancreatic Neoplasms', 'Phenylalanine', 'Urea'] | 4,341,740 | [['C04.557.470.200.025'], ['C04.557.470.035.100', 'C04.588.274.761.249', 'C04.588.322.475.249', 'C06.301.761.249', 'C06.689.667.249', 'C19.344.421.249'], ['D08.811.277.352.650.035'], ['A02.835.232', 'A10.165.265'], ['C04.557.470.200'], ['E05.196.401.402.236', 'E05.301.300.319.403'], ['E01.370.225.500.607', 'E01.370.225... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. | Culturing cells in three dimension (3D) provides an insight into their characteristics in vivo. We previously reported that human mesenchymal stem/stromal cells (hMSCs) cultured as 3D spheroids acquire enhanced anti-inflammatory properties. Here, we explored the effects of hMSC spheroids on macrophages that are critica... | ['Antibodies', 'Caspases', 'Cell Culture Techniques', 'Culture Media, Conditioned', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Cytokines', 'Dinoprostone', 'Fibroblasts', 'Gene Expression Regulation', 'Humans', 'Lectins, C-Type', 'Lipopolysaccharides', 'Macrophage Activation', 'Macrophages', 'Mannose-Binding Le... | 22,865,689 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['D27.720.470.305.250', 'E07.206.250'], ['D08.81... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fragmentation of therapeutic human immunoglobulin preparations. | Some commercial batches of human therapeutic immunoglobulins (Ig) have been found to show evidence of molecular fragmentation when examined by molecular sizing methodologies including sodium dodecyl sulphate polyacrylamide gel electrophoresis [SDS-PAGE] and size exclusion high performance liquid chromatography (SE-HPLC... | ['Chemical Phenomena', 'Chemistry, Physical', 'Humans', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Immunoglobulins', 'Peptide Fragments', 'Quality Control', 'Serine Endopeptidases'] | 8,578,729 | [['G02'], ['H01.181.529'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G02.380'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['D12.644.541'], ['J01.897.608'], ['D08.811.277.656.300.760', 'D08.811.277.656.959.350']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment. | The concept of cancer cells being hierarchically organized and arising from their own progenitor stem cells will have important implications on cancer therapy. If this hypothesis were to be true then the paucity of estrogen receptors in stem cells as well as their inherent drug resistance mechanisms pose a challenge to... | ['Aldehyde Dehydrogenase', 'Aldehyde Dehydrogenase 1 Family', 'Antineoplastic Agents', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Chemotherapy, Adjuvant', 'Extracellular Matrix', 'Female', 'Gene Expression', 'Humans', 'Immunohistochemistry', 'Isoenzymes', 'Kaplan-Meier Estimate', 'Neoadjuvant Therapy', 'Neoplasm Staging... | 19,911,270 | [['D08.811.682.657.163.249'], ['D08.811.682.657.163.249.188'], ['D27.505.954.248'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['E02.186.170', 'E02.319.170'], ['A11.284.295.310'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Natural killer activity against human K562 tumour cells during Plasmodium cynomolgi malarial infection of rhesus monkeys. | This study assessed the natural killer (NK) cell activity profile during Plasmodium cynomolgi infection in rhesus monkeys. There was a significant decrease in the NK cell activity in the peripheral blood leukocytes of infected monkeys during the early, ascending phase of infection. However, as the parasite load decreas... | ['Animals', 'Erythrocytes', 'Humans', 'Killer Cells, Natural', 'Leukocyte Count', 'Macaca mulatta', 'Malaria', 'Time Factors', 'Tumor Cells, Cultured'] | 2,257,166 | [['B01.050'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.1... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hormetic effects on longevity of hydrogen peroxide in Drosophila melanogaster flies living on a poorly nutritious medium. | Subjecting flies to a mild stress at a young age may increase longevity and protect against strong stresses occurring at middle age. The purpose of this article is to test whether a mild stress could also increase survival time of flies living in stressful conditions. Flies were transferred at middle age in vials where... | ['Adaptation, Physiological', 'Aging', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Behavior, Animal', 'Dose-Response Relationship, Drug', 'Drosophila melanogaster', 'Female', 'Heat Stress Disorders', 'Hydrogen Peroxide', 'Learning', 'Longevity', 'Male', 'Oxidants', 'Sex Characteristics', 'Sucrose'] | 17,192,807 | [['G07.025', 'G16.012.500'], ['G07.345.124'], ['G07.203.650.161'], ['B01.050'], ['F01.145.113'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['C26.522'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['F02.463.425', 'F0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Extracellular metabolites in the cortex and hippocampus of epileptic patients. | Interictal brain energy metabolism and glutamate-glutamine cycling are impaired in epilepsy and may contribute to seizure generation. We used the zero-flow microdialysis method to measure the extracellular levels of glutamate, glutamine, and the major energy substrates glucose and lactate in the epileptogenic and the n... | ['Adolescent', 'Adult', 'Cerebral Cortex', 'Chromatography, High Pressure Liquid', 'Electroencephalography', 'Epilepsy, Temporal Lobe', 'Extracellular Fluid', 'Female', 'Glucose', 'Glutamic Acid', 'Glutamine', 'Hippocampus', 'Humans', 'Lactic Acid', 'Male', 'Microdialysis', 'Middle Aged'] | 15,668,975 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211.200.885.287.500'], ['E05.196.181.400.300'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['A11.284.295.260', 'A12.207.270'], ['D09.947.875.359.448'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Does an advanced insulin education programme improve outcomes and health service use for people with Type 2 diabetes? A 5-year follow-up of the Newcastle Empowerment course. | OBJECTIVE: To show that an advanced diabetes education programme delivers sustained benefits to people with diabetes prescribed insulin and healthcare providers over and above those provided by basic diabetes education.METHODS: An historical cohort study of 68 people with Type 1 and 51 people with Type 2 diabetes on in... | ['Adult', 'Cardiovascular Diseases', 'Cohort Studies', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Glycated Hemoglobin A', 'Hospitalization', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Patient Education as Topic', ... | 20,002,481 | [['M01.060.116'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D09.400.430.937', 'D12.776... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Regulation of intracellular ceramide content in B16 melanoma cells. Biological implications of ceramide glycosylation. | We previously reported that ceramide released from glycosphingolipids (GSLs) by endoglycoceramidase was directly metabolized to GSLs, and thus the content of GSLs was constantly maintained in B16 melanoma cells (Ito, M., and Komori, H. (1996) J. Biol. Chem. 271, 12655-12660). In this study, the metabolism of ceramide r... | ['Animals', 'Ceramides', 'DNA Replication', 'Glucosyltransferases', 'Glycosphingolipids', 'Melanoma, Experimental', 'Mice', 'RNA, Messenger', 'Sphingomyelin Phosphodiesterase', 'Sphingomyelins', 'Transferases (Other Substituted Phosphate Groups)', 'Tumor Cells, Cultured'] | 10,085,144 | [['B01.050'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['G02.111.225', 'G05.226'], ['D08.811.913.400.450.460'], ['D09.400.410.420', 'D10.390.470', 'D10.570.877.360'], ['C04.557.465.625.650.510.525', 'C04.557.580.625.650.510.525', 'C04.557.665.510.525', 'C04.619.600',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using inpatient gradual diagnostics to identify the treatment strategy for lumbar back pain-Can treadmill gait analysis objectify the patients' declaration of pain relief? | BACKGROUND: Patients with chronic lumbar back pain (CLBP) often present with an altered gait profile, which is a crucial element of good functioning in everyday life. In patients with multisegmental spinal pathologies and incongruity between radiologic imaging and clinical presentation, inpatient gradual diagnostics (I... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anesthetics, Local', 'Anti-Inflammatory Agents', 'Back Pain', 'Bupivacaine', 'Female', 'Gait', 'Gait Analysis', 'Hospitalization', 'Humans', 'Injections, Epidural', 'Injections, Intra-Articular', 'Low Back Pain', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Pain Measurement', 'Sel... | 31,377,581 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['D27.505.954.158'], ['C23.888.592.612.107'], ['D02.065.199.239', 'D02.092.146.113.239'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['E01.370.600.250.250', 'N01.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sensitive and selective detection of the p53 gene based on a triple-helix magnetic probe coupled to a fluorescent liposome hybridization assembly via rolling circle amplification. | Developing a sensitive and selective sensing platform for the p53 gene and its mutation analysis is essential and may aid in early cancer screening and assessment of prognosis. Here, we developed a highly sensitive and selective p53 gene assay based on the coupling of a triple-helix magnetic probe (THMP) to a fluoresce... | ['Biosensing Techniques', 'DNA Probes', 'Fluorescent Dyes', 'Genes, p53', 'Humans', 'Liposomes', 'Nucleic Acid Amplification Techniques', 'Nucleic Acid Hybridization'] | 28,891,579 | [['E05.601.043'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
How do physicians define "light," "moderate," and "heavy" drinking? | Although widely used, terms associated with consumption of alcohol--such as "light," "moderate," and "heavy"--are unstandardized. Physicians conveying health messages using these terms therefore may impart confusing information to their patients or to other physicians. As an initial attempt to assess if informal standa... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Alcohol Drinking', 'Alcohol-Related Disorders', 'Alcoholism', 'Attitude of Health Personnel', 'Female', 'Fetal Alcohol Spectrum Disorders', 'Humans', 'Infant, Newborn', 'Male', 'Middle Aged', 'Patient Education as Topic', 'Pregnancy', 'Sex Factors'] | 9,726,266 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.145.317.269'], ['C25.775.100', 'F03.900.100'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.100.050', 'N05.300.100'], ['C13.703.277.220', 'C16.300.070', 'C25.775.100.087.323'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparative effectiveness and harms of intravitreal antivascular endothelial growth factor agents for three retinal conditions: a systematic review and meta-analysis. | Intravitreal antivascular endothelial growth factor (VEGF) agents are widely used to treat ocular conditions but the benefits and harms of these treatments are uncertain. We conducted a systematic review to compare the effects of aflibercept, bevacizumab and ranibizumab on best-corrected visual acuity (BCVA) changes, q... | ['Angiogenesis Inhibitors', 'Bevacizumab', 'Humans', 'Intravitreal Injections', 'Macular Edema', 'Ranibizumab', 'Receptors, Vascular Endothelial Growth Factor', 'Recombinant Fusion Proteins', 'Retinal Vein Occlusion', 'Treatment Outcome', 'Vascular Endothelial Growth Factor A', 'Visual Acuity', 'Wet Macular Degeneratio... | 30,409,915 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D12.776.124.486.485.114.224.060.375', 'D12.776.124.790.651.114.224.060.438', 'D12.776.377.715.548.114.224.200.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.475.500'], ['C11.768.585.439.245'], ['D12.776.124.486.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rhesus D genotyping in amniotic fluid. | Rhesus D genotyping by PCR of amniotic fluid offers a very valuable tool for prenatal care of Rhesus D-alloimmunized women. Misleading results have been reported for the method of Bennett et al. analysing the 3'-terminal end of the RhD gene. We have observed also problems with Rhesus D genotyping of DVI-variant samples... | ['Amniocentesis', 'Amniotic Fluid', 'Erythroblastosis, Fetal', 'Female', 'Genotype', 'Humans', 'Infant, Newborn', 'Isoantibodies', 'Polymerase Chain Reaction', 'Pregnancy', 'Rho(D) Immune Globulin', 'Risk Factors'] | 8,865,931 | [['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['A12.098', 'A16.378.149'], ['C13.703.277.060', 'C15.378.295', 'C16.300.060', 'C16.614.304', 'C20.306'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association between beliefs about medicines and self-medication with analgesics among patients with dental pain. | Self-medication with analgesics in dental pain management is a common practice as most of these medicines are available over-the-counter (OTC). The study aims to examine the relationship between beliefs about medicines and self-medication with analgesics in dental pain management in Malaysia. This cross-sectional study... | ['Adult', 'Aged', 'Analgesics', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Malaysia', 'Male', 'Middle Aged', 'Nonprescription Drugs', 'Pain Management', 'Prevalence', 'Self Medication', 'Thiophenes', 'Toothache', 'Young Adult'] | 30,071,006 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.487'], ['M01.060.116.630'], ['D26.530'], ['E02.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Environmental factors influencing flight activity of forensically important female blow flies in Central Europe. | In forensic entomology, evaluation of a possible delay between a person's death and insect colonization is crucial. We monitored the seasonal flight activities of the most abundant blow flies in an urban habitat in Frankfurt/Germany based on 152 sampling days between April and October 2017. Thirty-six thousand female s... | ['Animals', 'Biodiversity', 'Diptera', 'Female', 'Forensic Sciences', 'Germany', 'Larva', 'Postmortem Changes'] | 30,483,869 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['B01.050.500.131.617.720.500.500.750'], ['I01.198.780'], ['Z01.542.315'], ['B05.500.500', 'G07.345.500.550.500.500'], ['C23.550.260.224.617']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures. | PURPOSE: PNU-151774E [(S)-(+)-2-(4-(3-fluorobenzyloxy) benzylamino) propanamide, methanesulfonate] is a novel antiepileptic drug (AED) with a broad spectrum of activity in a variety of chemically and mechanically induced seizures. The objective of this study was to evaluate the activity of PNU-151774E in the amygdala f... | ['Acetates', 'Alanine', 'Amines', 'Amygdala', 'Animals', 'Anticonvulsants', 'Behavior, Animal', 'Benzylamines', 'Carbamazepine', 'Cyclohexanecarboxylic Acids', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Epilepsy, Complex Partial', 'Gabapentin', 'Kindling, Neurologic', 'Lamotrigine', 'Male', 'Phenyto... | 10,565,578 | [['D02.241.081.018', 'D10.251.400.045'], ['D12.125.042'], ['D02.092'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['D27.505.954.427.080'], ['F01.145.113'], ['D02.092.200', 'D02.455.426.559.389.140.210'], ['D03.633.300.240.127'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['C22.232... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Clinical observation of the therapeutic effect on posterior circulation ischemic vertigo treated with "xiao xingnao kaiqiao | OBJECTIVE: To observe the short-term and long-term clinical effect on posterior circulation ischemic vertigo treated with "xiao xingnao kaiqiao" acupuncture (minor regaining consciousness and opening orifice) and explore its effect mechanism.METHODS: Ninety patients with posterior circulation ischemic vertigo were rand... | ['Acupuncture Therapy', 'Basilar Artery', 'Humans', 'Ischemia', 'Treatment Outcome', 'Vertigo'] | 32,869,576 | [['E02.190.044'], ['A07.015.114.106'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C09.218.568.900.883', 'C10.597.951', 'C23.888.592.958']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Unilateral neglect, transient cognitive impairment and intercritical activity in Rolandic epilepsy]. | INTRODUCTION: Benign focal epilepsy in infancy with centro-temporal paroxysms is a frequent form of epilepsy within this group of epilepsies. Despite its relative benignity, however, it may be accompanied by neuropsychological deficits and therefore constitutes a suitable in vivo model for studying how the brain functi... | ['Child', 'Electroencephalography', 'Epilepsy, Rolandic', 'Humans', 'Male', 'Neuropsychological Tests'] | 17,492,612 | [['M01.060.406'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360.280', 'C10.228.140.490.493.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Computational site-directed mutagenesis studies of the role of the hydrophobic triad on substrate binding in cholesterol oxidase. | Cholesterol oxidase (ChOx) is a flavoenzyme that oxidizes and isomerizes cholesterol (CHL) to form cholest-4-en-3-one. Molecular docking and molecular dynamics simulations were conducted to predict the binding interactions of CHL in the active site. Several key interactions (E361-CHL, N485-FAD, and H447-CHL) were ident... | ['Amino Acid Sequence', 'Binding Sites', 'Catalysis', 'Catalytic Domain', 'Cholesterol Oxidase', 'Flavin-Adenine Dinucleotide', 'Hydrophobic and Hydrophilic Interactions', 'Kinetics', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Mutagenesis, Site-Directed', 'Protein Conformation', 'Substrate Specif... | 28,508,424 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['G02.130'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D08.811.682.047.436.350.150'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', 'D08.211.474.650.249', 'D13.695.667.138.506', 'D13.695.827... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Measurement of single soybean seed attributes by near-infrared technologies. A comparative study. | Four near-infrared spectrophotometers, and their associated spectral collection methods, were tested and compared for measuring three soybean single-seed attributes: weight (g), protein (%), and oil (%). Using partial least-squares (PLS) and four preprocessing methods, the attribute that was significantly most easily p... | ['Calibration', 'Reproducibility of Results', 'Seeds', 'Soybean Oil', 'Soybean Proteins', 'Soybeans', 'Spectroscopy, Near-Infrared'] | 22,831,652 | [['E05.978.155'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D10.212.302.380.800', 'D10.212.507.800', 'D10.627.700.880', 'D20.215.784.750.880', 'G07.203.300.375.400.750', 'J02.500.375.400.750'], ['D12.776.765.741', 'G07.203.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Italian register for retinoblastoma. Pros and cons of a retrospective statistical study. | In an attempt to verify some of the current conflicting results concerning the impact of relevant prognostic factors in the retinoblastoma therapy, the authors took into consideration, for statistical analysis, the series of 459 cases included in the Italian Registry for retrospective study of retinoblastoma. Although ... | ['Evaluation Studies as Topic', 'Eye Neoplasms', 'Humans', 'Italy', 'Random Allocation', 'Registries', 'Retinoblastoma', 'Retrospective Studies', 'Statistics as Topic'] | 1,923,316 | [['E05.337', 'N05.715.360.335'], ['C04.588.364', 'C11.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['C04.557.465.625... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Heterologous Expression of Ilicicolin H Biosynthetic Gene Cluster and Production of a New Potent Antifungal Reagent, Ilicicolin J. | Ilicicolin H is a broad-spectrum antifungal agent targeting mitochondrial cytochrome bc1 reductase. Unfortunately, ilicicolin H shows reduced activities in vivo. Here, we report our effort on the identification of ilicicolin H biosynthetic gene cluster (BGC) by genomic sequencing a producing strain, Neonectria sp. DH2,... | ['Antifungal Agents', 'Ascomycota', 'Benzaldehydes', 'Biosynthetic Pathways', 'Chromatography, High Pressure Liquid', 'Gene Expression Regulation, Fungal', 'Genes, Fungal', 'Molecular Structure', 'Multigene Family'] | 31,216,742 | [['D27.505.954.122.136'], ['B01.300.107'], ['D02.047.222'], ['G02.111.098', 'G03.493.100'], ['E05.196.181.400.300'], ['G05.308.330'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G02.111.570', 'G02.466'], ['G05.360.340.024.340.645']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cyclo-oxygenase-2 (COX-2) mRNA expression and hormone receptor status in breast cancer. | AIMS: The purpose of this study was to evaluate COX-2 mRNA expression with known clinical prognostic features of breast cancer, oestrogen/progesterone receptor status, tumour size and grade.METHODS: Total RNA was extracted from 45 frozen breast tumour (invasive) and 22 normal breast tissue samples. COX-2 mRNA transcrip... | ['Breast', 'Breast Neoplasms', 'Cyclooxygenase 2', 'Female', 'Humans', 'Lymphatic Metastasis', 'Membrane Proteins', 'RNA, Messenger', 'Receptors, Estrogen', 'Receptors, Progesterone'] | 16,650,963 | [['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['D08.811.600.720.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['D12.776.543'], ['D13.444.735.544'], ['D12.776.826.750.350', 'D12.776.930.778.350'], ['D12.776.826.750.765']] | ['Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Need for rescue treatment and its implication: stent retriever versus contact aspiration thrombectomy. | BACKGROUD: The need for rescue treatment (RT) may differ depending on first-line modality (stent retriever (SR) or contact aspiration (CA)) in endovascular thrombectomy (EVT). We aimed to investigate whether the type of first-line modality in EVT was associated with the need for RT.METHODS: We identified all patients w... | ['Aged', 'Aged, 80 and over', 'Angioplasty, Balloon', 'Brain Ischemia', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Registries', 'Stents', 'Stroke', 'Thrombectomy', 'Treatment Outcome'] | 30,842,306 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C10.228.140.300.150', 'C14.907.253.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical social work with young adult inpatients: perspective of patients, parents, and clinicians. | This article describes an empirical study designed to identify the unique role of the clinical social worker as a member of the hospital team in the treatment of young adult psychiatric inpatients. Fifty-five patients, their parents and social workers were interviewed at admission and 60 days later to ascertain: (1) in... | ['Adolescent', 'Adult', 'Consumer Behavior', 'Data Collection', 'Female', 'Hospital Bed Capacity, 100 to 299', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Massachusetts', 'Mental Disorders', 'Parents', 'Patient Care Team', 'Social Work, Psychiatric'] | 7,170,665 | [['M01.060.057'], ['M01.060.116'], ['F01.145.236'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N02.278.306.472.120'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.550.510'], ['F03'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Effect of the blood flow rate in the carotid artery on the hematocrit of the blood distributed to the brain]. | The red cell count and hematocrit were determined in the blood distributed to the rabbit brain through the carotid artery. Both parameters were found to be far greater than those in the blood distributed to the hind limb through the femoral artery. The decrease in the blood flow velocity in the carotid artery (caused b... | ['Animals', 'Blood Flow Velocity', 'Brain', 'Carotid Arteries', 'Erythrocyte Count', 'Erythrocyte Volume', 'Female', 'Hematocrit', 'Male', 'Rabbits'] | 7,093,497 | [['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A08.186.211'], ['A07.015.114.186'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.330', 'E05.242.195.107.330', 'G04.140.107.330', 'G09.188.105.330'], ['G09.188.130.370', 'G09.330.380.092.370'], ['E01.370... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postpartum aggression in rats: II. Dependence on maternal sensitivity to young and effects of experience with pregnancy and parturition. | Two experiments were carried out to explore the relation between postpartum aggressive behavior in rats and other aspects of maternal behavior. In Experiment 1, nulliparous females experimentally induced to behave maternally; i.e., sensitized, failed to show elevations in aggressive responding above levels seen in untr... | ['Aggression', 'Animals', 'Female', 'Humans', 'Labor, Obstetric', 'Male', 'Maternal Behavior', 'Postpartum Period', 'Pregnancy', 'Rats', 'Reaction Time'] | 7,190,160 | [['F01.145.126.125', 'F01.145.813.045'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326'], ['F01.829.263.370.215'], ['G08.686.702'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The importance of structured noise in the generation of self-organizing tissue patterns through contact-mediated cell-cell signalling. | Lateral inhibition provides the basis for a self-organizing patterning system in which distinct cell states emerge from an otherwise uniform field of cells. The development of the microchaete bristle pattern on the notum of the fruitfly, Drosophila melanogaster, has long served as a popular model of this process. We re... | ['Animal Structures', 'Animals', 'Body Patterning', 'Cell Communication', 'Drosophila melanogaster', 'Models, Biological', 'Pseudopodia', 'Signal Transduction'] | 21,084,342 | [['A13'], ['B01.050'], ['G07.345.500.100'], ['G04.085'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['E05.599.395'], ['A11.284.180.700'], ['G02.111.820', 'G04.835']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term, six-dimensional live-cell imaging for the mouse preimplantation embryo that does not affect full-term development. | Mammalian preimplantation embryonic development is achieved by tightly coordinated regulation of a great variety of temporal and spatial changes. Therefore, it would be valuable to analyze these events three-dimensionally and dynamically. We have previously developed a live-cell imaging method based on the expression o... | ['Animals', 'Blastocyst', 'Cell Survival', 'Diagnostic Imaging', 'Embryonic Development', 'Female', 'Gene Transfer Techniques', 'Green Fluorescent Proteins', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Mice, Inbred ICR', 'Mice, Transgenic', 'Microinjections', 'Models, Biological', 'Pregnancy', 'RNA, Mess... | 19,305,125 | [['B01.050'], ['A16.254.500'], ['G04.346'], ['E01.370.350'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E05.393.350'], ['D12.776.532.265'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.199.520.520.500', 'B01.050.150... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glucose tolerance and insulin response to glucose load before and after enzyme inducing therapy in subjects with glucose intolerance and patients with NIDDM having hyperinsulinemia or relative insulin deficiency. | We evaluated the role of insulin availability in the induction therapy of non-insulin dependent diabetes mellitus (NIDDM). Plasma glucose (BG) and insulin (IRI) response to glucose loading (OGTT) was investigated before and after placebo and phenobarbitone (PB) therapy in patients with glucose intolerance and NIDDM tre... | ['Adult', 'Antipyrine', 'Blood Glucose', 'C-Peptide', 'Diabetes Mellitus, Type 2', 'Diet, Diabetic', 'Female', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Insulin Secretion', 'Male', 'Microsomes, Liver', 'Middle Aged', 'Mixed Function Oxygenases', 'Models, Biological', 'Phenobarbital', 'Reference Values'] | 2,697,484 | [['M01.060.116'], ['D03.383.129.539.850.088'], ['D09.947.875.359.448.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.642.249.240', 'G07.203.650.240.240'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Calibrated LCD/TFT stimulus presentation for visual psychophysics in fMRI. | Standard projection techniques using liquid crystal (LCD) or thin-film transistor (TFT) technology show drastic distortions in luminance and contrast characteristics across the screen and across grey levels. Common luminance measurement and calibration techniques are not applicable in the vicinity of MRI scanners. With... | ['Brain Mapping', 'Calibration', 'Color Perception', 'Computer Terminals', 'Contrast Sensitivity', 'Data Display', 'Fiber Optic Technology', 'Humans', 'Image Processing, Computer-Assisted', 'Lighting', 'Magnetic Resonance Imaging', 'Photic Stimulation', 'Psychophysics', 'Regression Analysis', 'Reproducibility of Result... | 12,393,166 | [['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E05.978.155'], ['F02.463.593.932.217'], ['L01.224.230.260.115.500'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['F02.784.412.221', 'L01.296'], ['H01.671.617.249'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Ischemic mitral valve reconstruction and replacement: comparison of long-term survival and complications. | OBJECTIVE: This study reviews the 223 consecutive mitral valve operations for ischemic mitral insufficiency performed at New York University Medical Center between January 1976 and January 1996. The results for mitral valve reconstruction are compared with those for prosthetic mitral valve replacement.METHODS: From Jan... | ['Aged', 'Bioprosthesis', 'Comorbidity', 'Coronary Artery Bypass', 'Discriminant Analysis', 'Female', 'Follow-Up Studies', 'Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'Humans', 'Logistic Models', 'Male', 'Mitral Valve', 'Mitral Valve Insufficiency', 'Odds Ratio', 'Postoperative Complications', 'Pro... | 11,726,886 | [['M01.060.116.100'], ['E07.695.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E07.695.31... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Presence and extent of the primary health care attributes among children hospitalized for pneumonia. | OBJECTIVE: to analyze the presence and extent of the primary health care attributes among children hospitalized for pneumonia.METHOD: observational and retrospective study with hospital-based case-control design, developed in three hospitals associated to the Brazilian Unified Health System, located in a city of the St... | ['Brazil', 'Case-Control Studies', 'Child, Preschool', 'Female', 'Hospitalization', 'Humans', 'Infant', 'Male', 'Pneumonia', 'Primary Health Care', 'Retrospective Studies'] | 26,312,636 | [['Z01.107.757.176'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406.448'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['N04.590.233.727'], ['E05.318.372.500.500.500', ... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The quantification of HER2 and MYC gene fragments in cell-free plasma as putative biomarkers for gastric cancer diagnosis. | BACKGROUND: This study aimed to investigate the significance of circulating HER2 and MYC gene fragments quantification in the diagnosis of gastric cancer.METHODS: Levels of HER2 and MYC genes were evaluated by fluorescence in situ hybridization and real-time PCR in 81 gastric cancer tissues, and by real-time PCR in 36 ... | ['Aged', 'Biomarkers, Tumor', 'Female', 'Genes, myc', 'Humans', 'In Situ Hybridization, Fluorescence', 'Male', 'Receptor, ErbB-2', 'Reverse Transcriptase Polymerase Chain Reaction', 'Stomach Neoplasms'] | 24,670,359 | [['M01.060.116.100'], ['D23.101.140'], ['G05.360.340.024.340.375.500.791.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['D08.811.913.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of emergency departments among working age adults with disabilities: a problem of access and service needs. | OBJECTIVE: To examine the relationship between emergency department (ED) use and access to medical care and prescription medications among working age Americans with disabilities.DATA SOURCE: Pooled data from the 2006-2008 Medical Expenditure Panel Survey (MEPS), a U.S. health survey representative of community-dwellin... | ['Adolescent', 'Adult', 'Aged', 'Disabled Persons', 'Emergency Service, Hospital', 'Female', 'Health Care Surveys', 'Health Services', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Health Status', 'Humans', 'Insurance, Health', 'Male', 'Middle Aged', 'Socioeconomic Factors', 'United States', 'Yo... | 23,278,461 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.150'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N02.421'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Children of dialysis patients and selection of dialysis setting. | The authors interviewed hemodialysis patients, their families, and medical staff and found that some patients preferred dialysis at a medical facility, which allowed them to appear more "normal" before their children. Patients with more social support involved their children in dialysis at home. The author suggests tha... | ['Adaptation, Psychological', 'Adult', 'Attitude to Health', 'Child', 'Family', 'Female', 'Health Facilities', 'Hemodialysis, Home', 'Humans', 'Male', 'Parent-Child Relations', 'Renal Dialysis', 'Social Adjustment'] | 626,226 | [['F01.058'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['F01.829.263', 'I01.880.853.150'], ['N02.278'], ['E02.870.300.300', 'E02.912.800.300', 'N02.421.143.524.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290'], ['E02.870.300', 'E02.912.800'], ['F01.145.813.621']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Ecology of Rhodococcus (Corynebacterium) equi in soil on a horse-breeding farm. | The ecology of Rhodococcus (Corynebacterium) equi in soil was studied on a horse-breeding farm. R. equi was cultured from soil at a depth of 0, 10, and 20 cm on the six sites of the farm at monthly intervals for 10 months from March to December of 1983. The highest numbers of R. equi were found in the surface soil. The... | ['Actinomycetales', 'Animals', 'Corynebacterium', 'Feces', 'Female', 'Horses', 'Serotyping', 'Soil Microbiology'] | 3,750,818 | [['B03.510.024.049'], ['B01.050'], ['B03.510.024.250', 'B03.510.460.400.400.200'], ['A12.459'], ['B01.050.150.900.649.313.984.235.472'], ['E01.370.225.812.742', 'E01.370.225.875.150.125.890', 'E05.200.812.742', 'E05.200.875.150.125.890', 'E05.478.594.780'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Activation and cytokine profile of monocyte derived dendritic cells in leprosy: in vitro stimulation by sonicated Mycobacterium leprae induces decreased level of IL-12p70 in lepromatous leprosy. | Dendritic cells (DCs) play a pivotal role in the connection of innate and adaptive immunity of hosts to mycobacterial infection. Studies on the interaction of monocyte-derived DCs (MO-DCs) using Mycobacterium leprae in leprosy patients are rare. The present study demonstrated that the differentiation of MOs to DCs was ... | ['Antigens, Bacterial', 'Case-Control Studies', 'Cytokines', 'Dendritic Cells', 'Female', 'Humans', 'In Vitro Techniques', 'Interleukin-12', 'Leprosy, Lepromatous', 'Male', 'Monocytes', 'Mycobacterium leprae', 'Retrospective Studies'] | 26,222,022 | [['D23.050.161'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.644.276.374.465.512', 'D12.776... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Advanced techniques for characterization of organic matter from anaerobically digested grapemarc distillery effluents and amended soils. | The effects of grapemarc distillery effluents on the quality of soil organic matter is extremely important to ensure the environmentally-safe and agronomically efficient use of these materials as organic amendment. In this work, the effects of the application of untreated (UG) and anaerobically digested grapemarc disti... | ['Distillation', 'Environmental Monitoring', 'Fruit', 'Humans', 'Humic Substances', 'Industrial Waste', 'Italy', 'Soil Pollutants'] | 21,573,856 | [['E05.196.155.249'], ['N06.850.460.350.080', 'N06.850.780.375'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['D20.944.420', 'N06.850.460.710.420'], ['Z01.542.489'], ['D27.888.284.756']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Breakpoint of a Y chromosome pericentric inversion in the DAZ gene area. A case report. | BACKGROUND: The presence of a spermatogenesis locus (gene or gene complex) in the euchromatic region of the long arm of the Y chromosome (Yq11), defined as azoospermia factor on the basis of gross structural rearrangement, was detected. The gene family responsible for different spermatogenetic defects is "deleted in az... | ['Adult', 'Centrosome', 'Chromosome Aberrations', 'Chromosome Deletion', 'Chromosome Disorders', 'Deleted in Azoospermia 1 Protein', 'Humans', 'Male', 'Oligospermia', 'RNA-Binding Proteins', 'Y Chromosome'] | 10,948,474 | [['M01.060.116'], ['A11.284.430.214.190.750.585.160', 'A11.284.430.214.190.750.820.500.500'], ['C23.550.210', 'G05.365.590.175'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['C16.131.260', 'C16.320.180'], ['D12.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Electromotor feeding responses of primate ileum and colon. | Serosal bipolar electrodes to record spike discharges and strain gauge force transducers to record circular muscle contractions were placed in pairs on the terminal ileum, cecum, right colon at the ileocecal valve, ascending colon, and proximal transverse colon of sixteen primates. After an overnight fast, electromotor... | ['Animals', 'Colon', 'Electrophysiology', 'Fasting', 'Food', 'Gastrointestinal Motility', 'Haplorhini', 'Ileum', 'Macaca', 'Muscle Contraction', 'Muscle, Smooth', 'Time Factors'] | 103,452 | [['B01.050'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['H01.158.344.528', 'H01.158.782.236'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['G07.203.300', 'J02.500'], ['G10.261.360'], ['B01.050.150.900.649.313.988.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Monocyte chemoattractant protein-1 gene (MCP-1) polymorphisms are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study. | The CC chemokine monocyte chemoattractant protein (MCP)-1/CCL2 is involved in the formation, progression, and destabilization of atheromatous plaques and plays an essential role in postinfarction remodeling. The aim of the present study was to evaluate the role of MCP-1 gene polymorphisms as susceptibility markers for ... | ['Alleles', 'Biomarkers', 'Case-Control Studies', 'Chemokine CCL2', 'Comorbidity', 'Coronary Artery Disease', 'Female', 'Gene Frequency', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Haplotypes', 'Humans', 'Male', 'Mexico', 'Middle Aged', 'Odds Ratio', 'Polymorphism, Single Nucleotid... | 26,277,553 | [['G05.360.340.024.340.030'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['N05.715.350.225', 'N06.850.490.687'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Apomorphine and glycoprotein synthesis during consolidation. | The dopamine agonist, apomorphine, was injected intrahippocampally immediately after acquisition of a brightness discrimination task, which was motivated by footshock in rats. This led to an increase in the incorporation of L-fucose into total proteins which were measured in the hippocampus 7-9 hours later. In behavior... | ['Animals', 'Apomorphine', 'Ascorbic Acid', 'Discrimination Learning', 'Fucose', 'Glycoproteins', 'Hippocampus', 'Learning', 'Male', 'Nerve Tissue Proteins', 'Rats', 'Rats, Inbred Strains'] | 7,122,655 | [['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['F02.463.425.280'], ['D09.254.488'], ['D09.400.430', 'D12.776.395'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['F02.463.425', 'F02.784.629.529']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Opening and closure forces of sliding mechanisms of different self-ligating brackets. | UNLABELLED: Self-ligating brackets engage the wire by means of a slide mechanism. Forces that have to be applied to open and close the sliding mechanism of brackets are still unknown.OBJECTIVE: The aim of this study was to measure and compare the opening and closure forces of different self-ligating brackets.MATERIAL A... | ['Analysis of Variance', 'Biomechanical Phenomena', 'Materials Testing', 'Orthodontic Appliance Design', 'Orthodontic Brackets', 'Reference Values', 'Stainless Steel', 'Statistics, Nonparametric'] | 23,857,652 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G01.154.090', 'G01.374.089'], ['E05.570'], ['E05.320.274', 'E06.658.450', 'E06.912.675'], ['E06.658.453.255.500'], ['E05.978.810'], ['D01.490.800.900', 'D01.552.033.847.681', 'D25.058.807.681', 'J01.637.051.058.807.681'], ['E05.318.740.995', 'N05.715... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Acquired ocular toxoplasmosis. A fluorescein angiography study. | A 31-year-old man exhibited a bilateral deterioration of vision over the course of 1 week. The right fundus showed the picture of a central vein occlusion, and the left of a disseminated choroiditis. Indirect immunofluorescent testing indicated a titer of 1:2048 for toxoplasmosis. Fluorescein angiography revealed a hit... | ['Adult', 'Animals', 'Antibodies, Protozoan', 'Fluorescein Angiography', 'Follow-Up Studies', 'Fundus Oculi', 'Humans', 'Male', 'Pyrimethamine', 'Sulfadiazine', 'Toxoplasma', 'Toxoplasmosis, Ocular', 'Visual Acuity'] | 1,800,924 | [['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['E01.370.370.050.350', 'E01.370.380.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A new evaluation of pancreatic function after pancreatoduodenectomy using secretin magnetic resonance cholangiopancreatography. | BACKGROUND: The remnant pancreatic function after pancreatoduodenectomy influences greatly postoperative quality of life. However, it has been difficult to evaluate the exocrine remnant pancreatic function postoperatively. The aim of this study was to assess the usefulness of secretin-stimulated magnetic resonance chol... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bile Ducts', 'Feasibility Studies', 'Female', 'Glucose Tolerance Test', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pancreas', 'Pancreatic Function Tests', 'Pancreaticoduodenectomy', 'Postoperative Period', 'Secretin', 'Time Factors'] | 9,776,159 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.159.183'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.11... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Brain abnormalities in fucosidosis: transplantation or supportive therapy? | Fucosidosis is a rare lysosomal storage disease caused by á-fucosidase deficiency, which leads to progressive neurological deterioration and death. Hematopoietic stem cell transplantation is the best curative therapy if performed during the early stages of disease. We report two fucosidosis patients with brain abnormal... | ['Atrophy', 'Brain', 'Child, Preschool', 'Cord Blood Stem Cell Transplantation', 'Developmental Disabilities', 'Disease Progression', 'Female', 'Fucosidosis', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Infant', 'Male', 'Treatment Outcome'] | 28,238,202 | [['C23.300.070'], ['A08.186.211'], ['M01.060.406.448'], ['E02.095.147.500.500.312', 'E04.936.225.687.312'], ['F03.625.421'], ['C23.550.291.656'], ['C10.228.140.163.100.435.295', 'C16.320.565.189.435.295', 'C16.320.565.202.303', 'C16.320.565.595.554.295', 'C18.452.132.100.435.295', 'C18.452.648.189.435.295', 'C18.452.64... | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Parallel placement of Excluder legs for treatment of type IIIb endoleaks caused by fabric tear after endovascular aneurysm repair. | A total of 576 patients underwent endovascular aneurysm repair using main body devices for treatment of abdominal aortic aneurysms or iliac artery aneurysms. During follow-up, type IIIb endoleaks caused by fabric tear occurred in six patients (1.0% [6/576]). The device used was Zenith (Cook Medical, Bloomington, Ind) i... | ['Aged', 'Aged, 80 and over', 'Aortic Aneurysm, Abdominal', 'Aortography', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Computed Tomography Angiography', 'Echocardiography, Doppler, Color', 'Embolization, Therapeutic', 'Endoleak', 'Endovascular Procedures', 'Humans', 'Iliac Aneurysm', 'Male', 'Pr... | 28,705,593 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335',... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Relationship between single nucleotide polymorphisms in thiopurine methyltransferase gene and tolerance to thiopurines in acute leukemia]. | OBJECTIVE: For the purpose of clarifying the influence of thiopurine methyltransferase (TPMT) gene single nucleotide polymorphisms (SNPs) on the efficacy of thiopurines and risk for its toxicity and therefore improving the safety and efficacy of thiopurines, the authors investigated TPMT genotype in acute leukemia in c... | ['Acute Disease', 'Adolescent', 'Antimetabolites, Antineoplastic', 'Child', 'Child, Preschool', 'Chromatography, Liquid', 'Drug Resistance, Neoplasm', 'Exons', 'Female', 'Gene Frequency', 'Genotype', 'Humans', 'Infant', 'Leukemia', 'Male', 'Mercaptopurine', 'Methyltransferases', 'Polymerase Chain Reaction', 'Polymorphi... | 14,723,818 | [['C23.550.291.125'], ['M01.060.057'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['M01.060.406'], ['M01.060.406.448'], ['E05.196.181.400'], ['G07.690.773.984.395'], ['G05.360.340.024.340.137.232'], ['G05.330'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], [... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Robust inter-subject audiovisual decoding in functional magnetic resonance imaging using high-dimensional regression. | Major methodological advancements have been recently made in the field of neural decoding, which is concerned with the reconstruction of mental content from neuroimaging measures. However, in the absence of a large-scale examination of the validity of the decoding models across subjects and content, the extent to which... | ['Algorithms', 'Brain', 'Brain Mapping', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging'] | 28,939,433 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A rapid method for the separation of rat pancreatic islets from collagenase-digested pancreas using Percoll. | The isolation of pancreatic islets from collagenase-digested Wistar rat pancreas was shown by the sedimentation method at a unit gravity using Percoll solution with a density of 1.041 g/ml. The density of digested exocrine tissues was in the range of 1.013-1.041 g/ml, while that of purely isolated islets was in the nar... | ['Animals', 'Cell Separation', 'Glucose', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Male', 'Microbial Collagenase', 'Povidone', 'Rats', 'Rats, Inbred Strains', 'Silicon Dioxide'] | 6,284,493 | [['B01.050'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['D09.947.875.359.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', 'A06.300.414'], ['D08.811.277.656.300.480.205.500', 'D08.811.277.656.675.374.205.500'], ['D02.455.326.271.884.533.699'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
An upstream open reading frame impedes translation of the huntingtin gene. | Expansion of a CAG tract within the huntingtin gene, leading to the production of a protein with an expanded polyglutamine tract, is responsible for Huntington's disease. We show here that the 5' untranslated region (UTR) of the huntingtin gene plays an important role in controlling the synthesis of huntingtin. In part... | ["5' Untranslated Regions", 'Animals', 'Base Sequence', 'COS Cells', 'Gene Expression Regulation', 'Genes, Reporter', 'HeLa Cells', 'Humans', 'Huntingtin Protein', 'Molecular Sequence Data', 'Mutation', 'Nerve Tissue Proteins', 'Nuclear Proteins', 'Open Reading Frames', 'Promoter Regions, Genetic', 'Protein Biosynthesi... | 12,466,534 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.172.500', 'A11.329.228.220'], ['G05.308'], ['G05.360.340.024.340.435'], ['A11.251.210.190.400', 'A11.251.860.18... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Self-stigma by people diagnosed with schizophrenia, depression and anxiety: Cross-sectional survey design. | AIM: This study investigated self-attitudes towards schizophrenia, depression and anxiety.METHODS: A survey was conducted with 564 people with a schizophrenia, depression and anxiety who are currently being treated at a psychiatric clinic in Amman, Jordan.RESULTS: The research found that stigma towards schizophrenia, d... | ['Adolescent', 'Adult', 'Anxiety Disorders', 'Cross-Sectional Studies', 'Depressive Disorder', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Saudi Arabia', 'Schizophrenia', 'Self Concept', 'Social Stigma', 'Young Adult'] | 28,198,022 | [['M01.060.057'], ['M01.060.116'], ['F03.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.600.300'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.252.245.500.750'], ['F03.700.750'], ['F01.752.747.792'], ['F... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Enterotoxemia in newborn calves due to Cl. perfringens types A, C and D]. | The clinical symptoms and the morphologic picture of calf enterotoxemia are described. Studied were a total of thirty-two dead and slaughtered animals. Bacteriologically, the disease was shown to be caused by types A, D, and C of Clostridium perfringens. Types C and D proved pathogenic for guinea pigs, while type A did... | ['Animals', 'Animals, Newborn', 'Cattle', 'Cattle Diseases', 'Clostridium Infections', 'Clostridium perfringens', 'Enterotoxins', 'Guinea Pigs', 'Mice'] | 2,876,542 | [['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C01.150.252.410.222'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['D23.946.330'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.992.635.505.500']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Two-dimensional echocardiography during the acute phase of myocardial infarction. Diagnostic and prognostic value]. | A bidimensional cardiac sonogram was performed in 152 consecutive patients with in 24 hours after hospitalization in the intensive care unit for acute myocardial infarction, in order to evaluate the contribution of this technique to the diagnosis, determination of early complication and the prognosis. For this study, t... | ['Adult', 'Aged', 'Aged, 80 and over', 'Echocardiography', 'Electrocardiography', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Prognosis', 'Prospective Studies', 'Shock, Cardiogenic'] | 2,604,364 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.35... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Is the risk of pneumocystosis predictable in Wegener's disease?]. | Twelve cases of Pneumocystis pneumonia in patients with Wegener's granulomatosis were compared with a control-group of 32 patients. Our study showed that the dose of cyclophosphamide received in the first three months and a profound lymphocytopenia were strongly predictive of a risk of Pneumocystis carinii pneumonia in... | ['Cyclophosphamide', 'Granulomatosis with Polyangiitis', 'Humans', 'Lymphopenia', 'Pneumonia, Pneumocystis', 'Retrospective Studies', 'Risk Factors'] | 8,009,021 | [['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['C08.381.483.950', 'C14.907.940.897.249.750', 'C20.111.193.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.553.546.605', 'C20.673.627'], ['C01.150.703.534.700', 'C01.150.703.770.700', 'C01.748.435.700', 'C01.748.610.675', 'C08.381.472.700', 'C0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Origin of cell contrast in offset aperture adaptive optics ophthalmoscopy. | Offset aperture and split detector imaging are variants of adaptive optics scanning ophthalmoscopy recently introduced to improve the image contrast of retinal cells. Unlike conventional confocal scanning ophthalmoscopy, these approaches collect light laterally decentered from the optical axis. A complete explanation o... | ['Animals', 'Mice', 'Ophthalmoscopy', 'Optical Phenomena', 'Retina', 'Signal-To-Noise Ratio'] | 32,058,484 | [['B01.050'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.380.560'], ['G01.590'], ['A09.371.729'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Developmental characteristics of figure drawings made by boys and girls ages five through eleven. | 526 children from the ages of 5 yr. through 11 yr. (257 boys and 269 girls) responded when asked to draw the figure of a man. Of the 68 characteristics investigated the girls' responses were significantly different from the boys' on 41 items (60%) while boys' responses were significantly different on 28 items (41%). Al... | ['Art', 'Child', 'Child Development', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Psychometrics', 'Psychomotor Performance', 'Sex Factors'] | 2,326,128 | [['K01.093'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.780'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['N05.715.350.675', 'N06.850.490.875']] | ['Humanities [K]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Erythropoietin promotes hippocampal neurogenesis in in vitro models of neonatal stroke. | The hippocampus is often injured in neonatal stroke. We have investigated the effect of erythropoietin (EPO) on oxygen-glucose deprived hippocampal slices and hypoxic progenitor cells. EPO improved survival of the organotypic hippocampal slices with significantly less cell death in the dentate gyrus and an increased nu... | ['Analysis of Variance', 'Animals', 'Blotting, Western', 'Cell Hypoxia', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Erythropoietin', 'Glucose', 'Hippocampus', 'Immunohistochemistry', 'Neurogenesis', 'Neurons', 'Organ Culture Techniques', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Erythropoietin', 'Stem... | 20,117,210 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G03.197.300', 'G04.270.300'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['D12.644.276.374.410.240.150', 'D12.776... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The organization of the human-plasminogen-activator-inhibitor-1 gene. Implications on the evolution of the serine-protease inhibitor family. | Plasminogen activator inhibitor 1 (PAI-1) is a member of the serine protease inhibitor super family (SERPINS) which is thought to play an integral role in the control of plasminogen activation. PAI-1 inhibits both tissue-type plasminogen activator and urokinase-type plasminogen activator and may therefore be implicated... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Biological Evolution', 'Cloning, Molecular', 'Exons', 'Genes', 'Glycoproteins', 'Humans', 'Introns', 'Molecular Sequence Data', 'Oligonucleotide Probes', 'Plasminogen Inactivators', 'Promoter Regions, Genetic', 'Protease Inhibitors', 'Rats', 'Serine Proteinase Inhibi... | 3,262,512 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['E05.393.220'], ['G05.360.340.024.340.137.232'], ['G05.360.340.024.340'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A(4) and lipoxin A(4). | Proliferative states such as chronic inflammation, ischemic diseases, and cancer are often accompanied by intense angiogenesis, a highly orchestrated process involving vessel sprouting, endothelial cell migration, proliferation, and maturation. Aspirin-triggered lipoxins (ATLs), the 15R enantiomeric counterparts of lip... | ['Angiogenesis Inhibitors', 'Anti-Inflammatory Agents, Non-Steroidal', 'Cell Division', 'Cell Movement', 'Cells, Cultured', 'Chemotaxis', 'DNA Fragmentation', 'Eicosanoids', 'Endothelial Growth Factors', 'Endothelium, Vascular', 'Humans', 'Hydroxyeicosatetraenoic Acids', 'Immunohistochemistry', 'Leukotriene A4', 'Lipid... | 11,805,195 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['F01.145.113.780.500', 'F01.145.875.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary phosphorus supply, egg-shell deposition and plasma inorganic phosphorus in laying hens. | 1. In 2 experiments the effects of dietary phosphorus on relationships between plasma inorganic phosphorus concentration (Pi), shell and egg production and depletion states were measured in brown laying hens. 2. In a 12-week experiment dietary phosphorus concentrations from conventionally deficient (1.6 g non-phytate-p... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Bone and Bones', 'Chickens', 'Cross-Over Studies', 'Diet', 'Egg Shell', 'Female', 'Nutritional Requirements', 'Oviposition', 'Phosphorus', 'Phosphorus, Dietary', 'Random Allocation'] | 11,337,973 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['A02.835.232', 'A10.165.265'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.203.650.240'], ['A13.316'], ['G07.203.650.620'], ['G08.686.784.480'], ['... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Efficiency of host utilisation by coleopteran parasitoid. | In insect larvae, optimising food utilisation with respect to available meals and time is essential for achieving maximum adult body size, which is a relevant proxy of fitness. We studied the efficiency of food conversion, body size, mortality, and development time in a solitary idiobiont ectoparasitoid, Brachinus expl... | ['Animals', 'Body Size', 'Coleoptera', 'Female', 'Host-Parasite Interactions', 'Larva', 'Male'] | 21,968,287 | [['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.500.131.617.720.500.500.375'], ['G16.527.200.400'], ['B05.500.500', 'G07.345.500.550.500.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
White-knuckle ride to theatre. | Preventing or reducing anxiety in surgical patients can lead to better recovery with fewer complications and earlier discharge (Baldwin 1993). There seems to be little evidence, however, that effective nursing measures are taken to reduce anxiety. This article presents a critical review of the literature on preoperativ... | ['Anxiety', 'Fear', 'Humans', 'Nursing Assessment', 'Patient Education as Topic', 'Preoperative Care'] | 10,373,941 | [['F01.470.132'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.508.480'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Mentored simulation training improves procedural skills in cardiac catheterization: a randomized, controlled pilot study. | BACKGROUND: Despite valuable supplemental training resources for surgical skill acquisition, utility of virtual reality simulators to improve skills relevant to performing cardiac catheterization has not been evaluated.METHODS AND RESULTS: Post baseline cardiac catheterization performance assessment, 27 cardiology trai... | ['Adult', 'Cardiac Catheterization', 'Cardiology', 'Clinical Competence', 'Computer Simulation', 'Education, Medical, Graduate', 'Female', 'Humans', 'Learning Curve', 'Linear Models', 'Male', 'Mentors', 'Motor Skills', 'Ontario', 'Pilot Projects', 'Task Performance and Analysis'] | 23,048,053 | [['M01.060.116'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['H02.403.429.163'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['L01.224.160'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.629.529.274'], ['E05.318.740.500.500', 'E05.318.740.750.425... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Minimally symptomatic severe hypercalcaemia in a patient with parathyroid carcinoma. | The case of a 38 years old man with generalized pains fatigue, anorexia, constipation, polyuria serum calcium level of 20.6mg/dl in paired renal function parathyroid hormone is presented. Sestamibi scan showed a functioning left inferior parathyroid tumor, which was successfully removed. Before surgery he was managed w... | ['Adult', 'Calcium', 'Carcinoma', 'Follow-Up Studies', 'Humans', 'Hypercalcemia', 'Male', 'Parathyroid Hormone', 'Parathyroid Neoplasms', 'Parathyroidectomy', 'Severity of Illness Index', 'Thyroidectomy'] | 16,454,135 | [['M01.060.116'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C04.557.470.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.174.451', 'C18.452.950.340'], ['D06.472.699.590', 'D12.644.548.587'], ['C04.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Allogeneic hematopoietic cell transplant for prolymphocytic leukemia. | The poor prognosis of patients with prolymphocytic leukemia (PLL) has led some clinicians to recommend allogeneic hematopoietic cell transplant (HCT). However, the data to support this approach is limited to case-reports and small case series. We reviewed the database of the Center for International Blood and Marrow Tr... | ['Adult', 'Aged', 'Disease-Free Survival', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Leukemia, Prolymphocytic', 'Male', 'Middle Aged', 'Prognosis', 'Transplantation Conditioning'] | 19,961,946 | [['M01.060.116'], ['M01.060.116.100'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.565', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Access to assistive technology in two Southern African countries. | BACKGROUND: Millions of people in Southern Africa are deprived of basic human rights such as the right to education and work because of the large and growing unmet demand for assistive technologies (AT). Evidence is needed to better characterize the lack of AT access.METHODS: This study serves to identify the sociodemo... | ['Botswana', 'Disabled Persons', 'Eswatini', 'Female', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Humans', 'Qualitative Research', 'Self-Help Devices', 'Young Adult'] | 30,340,484 | [['Z01.058.290.175.230'], ['M01.150'], ['Z01.058.290.175.300'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.241.850'], ['E07.796'], ['M01.060.116.815']] | ['Geographicals [Z]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Percutaneous cryotherapy for metastatic bladder cancer: experience with 23 patients. | Bladder cancer is the most common malignancy of the urinary tract and in many patients is metastatic at diagnosis. Chemotherapy is the standard treatment for these patients but has serious side effects and in many patients is not tolerated. To avoid the side effects of systemic chemotherapy, patients with late stage bl... | ['Abdominal Neoplasms', 'Adenocarcinoma', 'Aged', 'Carcinoma, Squamous Cell', 'Carcinoma, Transitional Cell', 'Cryosurgery', 'Cryotherapy', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Middle Aged', 'Treatment Outcome', 'Urinary Bladder Neoplasms'] | 24,368,268 | [['C04.588.033'], ['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.557.470.200.430'], ['E04.014.180'], ['E02.258'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effectiveness of compensating filters in the presence of tissue inhomogeneities. | CT based 3D treatment planning systems (3DTPS) can be used to design compensating filters that, in addition to missing tissue compensation, can account for tissue inhomogeneities. The use of computer-driven systems provides a practical, convenient, and accurate method of fabricating compensating filters. In this work, ... | ['Biophysics', 'Bone and Bones', 'Calcium Sulfate', 'Phantoms, Imaging', 'Polystyrenes', 'Radiation Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, High-Energy', 'Wood'] | 12,841,791 | [['H01.158.344', 'H01.671.100'], ['A02.835.232', 'A10.165.265'], ['D01.146.375', 'D01.578.215', 'D01.875.800.800.850.125'], ['E07.671'], ['D02.455.426.559.389.150.750.800.830', 'D05.750.716.579', 'D25.720.716.579', 'J01.637.051.720.716.579'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E02.950.825', 'L01.313.5... | ['Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Identification of sylvatic Trichinella (T3) in foxes from France. | Thirty-three foxes (Vulpes vulpes) from a sample of 1912 collected in France were found to be infected with Trichinella spp. Four isolates were obtained for genetic identification. Isoenzymatic and biological analysis of these isolates revealed the presence of two distinct genetic types of Trichinella, Trichinella spir... | ['Animals', 'Animals, Wild', 'Disease Reservoirs', 'Foxes', 'France', 'Mice', 'Rats', 'Trichinella', 'Trichinellosis'] | 1,763,479 | [['B01.050'], ['B01.050.050.300'], ['N06.850.520.203.250'], ['B01.050.150.900.649.313.750.250.216.250'], ['Z01.542.286'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.500.500.294.100.275.780.608'], ['C01.610.335.508.100.275.882']] | ['Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Recombinant Von Willebrand factor concentrate in 2A Von Willebrand disease: comparison to plasma-derived Von Willebrand factor concentrate therapy. | : Type 2A sub-type of Von Willebrand disease (VWD) is characterized by the loss of high molecular weight multimers. Several plasma-derived Von Willebrand factor concentrates (PD-VWFC) are available for treatment and recently a recombinant VWF concentrate (rVWFC) has been approved for use in VWD for adults in the United... | ['Adult', 'Blood Proteins', 'Epistaxis', 'Factor VIII', 'Humans', 'Protein Multimerization', 'Recombinant Proteins', 'United States', 'von Willebrand Disease, Type 2', 'von Willebrand Factor'] | 31,090,598 | [['M01.060.116'], ['D12.776.124'], ['C08.460.261', 'C09.603.261', 'C23.550.414.712', 'C23.888.852.040'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.694'], ['D12.776.828'], ['Z01.107.567.875'], ['C15.378.100.100.900.200', 'C15.378.100.141.900.200... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Primary hyperparathyroidism associated with a giant cell tumor: One case in the distal radius. | Hyperparathyroidism can present itself as brown tumors (or osteolytic expansive lesions) that usually disappear after normalization of calcium and phosphate levels. It rarely occurs simultaneously with a giant cell tumor. The authors report one case of a localized form at the distal radius in a patient being followed f... | ['Aged', 'Female', 'Giant Cell Tumor of Bone', 'Giant Cell Tumors', 'Humans', 'Hyperparathyroidism, Primary', 'Radius'] | 26,433,838 | [['M01.060.116.100'], ['C04.557.450.565.380.380', 'C04.557.450.565.575.420'], ['C04.557.450.565.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355.239'], ['A02.835.232.087.090.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
First results on label-free detection of DNA and protein molecules using a novel integrated sensor technology based on gravimetric detection principles. | A novel integrated bio-sensor technology based on thin-film bulk acoustic wave resonators on silicon is presented and the feasibility of detecting DNA and protein molecules proofed. The detection principle of these sensors is label-free and relies on a resonance frequency shift caused by mass loading of an acoustic res... | ['Biosensing Techniques', 'Coated Materials, Biocompatible', 'DNA', 'Electrochemistry', 'Electrodes', 'Equipment Design', 'Equipment Failure Analysis', 'Feasibility Studies', 'Gravitation', 'In Situ Hybridization', 'Pilot Projects', 'Protein Array Analysis', 'Proteins', 'Reproducibility of Results', 'Sensitivity and Sp... | 14,683,645 | [['E05.601.043'], ['D25.130.420', 'J01.637.051.130.420'], ['D13.444.308'], ['H01.181.529.307'], ['E07.305.250'], ['E05.320'], ['E05.325.192'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['G01.060.350'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.62... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
The Yersinia enterocolitica phage shock proteins B and C can form homodimers and heterodimers in vivo with the possibility of close association between multiple domains. | The Yersinia enterocolitica phage shock protein (Psp) stress response is essential for virulence and for survival during the mislocalization of outer membrane secretin proteins. The cytoplasmic membrane proteins PspB and PspC are critical components involved in regulating psp gene expression and in facilitating toleran... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Dimerization', 'Gene Expression Regulation, Bacterial', 'Membrane Proteins', 'Molecular Sequence Data', 'Protein Binding', 'Protein Structure, Tertiary', 'Transcription Factors', 'Yersinia enterocolitica'] | 21,856,846 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.206', 'G03.230'], ['G05.308.300'], ['D12.776.543'], ['L01.453.245.667'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.610'], ['D12.776.930'], ['B03.440.450.425.900.300', 'B03.660.250.150.950.160']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A case-management program of medium intensity does not improve cardiovascular risk factor control in coronary artery disease patients: the Heartcare I trial. | BACKGROUND: Case-management programs for secondary prevention of coronary artery disease that utilize extensive resources can reduce cardiovascular risk factors, but less intensive approaches have failed to show benefits. This randomized trial evaluated whether a medium intensity case-management program improves risk f... | ['Blood Pressure', 'Body Mass Index', 'Case Management', 'Cholesterol', 'Coronary Disease', 'Female', 'Hospitalization', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Motivation', 'Risk Factors'] | 11,343,668 | [['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['N04.590.233.624.250'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C14.280.647.250', 'C14.907.585.250'], ['E02.760.400', 'N02.421.585.400'], ['B01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Can the pituitary secrete directly to the brain? (Affirmative anatomical evidence). | Vascular casts of 10 rhesus monkey pituitary glands and three vascular casts of the rhesus monkey cavernous sinus were examined by scanning electron microscopy. A continuous neurohypophyseal capillary bed was found uniting the infundibulum, infundibular stem, and infundibular process. The neurophypophysis was supplied ... | ['Animals', 'Arteries', 'Capillaries', 'Circle of Willis', 'Dura Mater', 'Haplorhini', 'Hypothalamus', 'Macaca mulatta', 'Microscopy, Electron, Scanning', 'Pituitary Gland', 'Pituitary Gland, Anterior', 'Pituitary Gland, Posterior', 'Veins'] | 105,877 | [['B01.050'], ['A07.015.114'], ['A07.015.461.165'], ['A07.015.114.228.351'], ['A08.186.566.395'], ['B01.050.150.900.649.313.988.400'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A06.300.747', 'A06.688.357... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Report on 16 cases of small intestine ascariasis diagnosed by capsule endoscopy]. | The clinical data and capsule endoscopy image of 16 adult patients with small intestine ascariasis were reviewed and analyzed retrospectively from June 2006 to June 2012 in West China Hospital. Among the 16 patients, 15 cases manifested as gastrointestinal bleeding, 15 cases showed anemia (3 severe, 10 moderate, and 2 ... | ['Adult', 'Aged', 'Animals', 'Ascariasis', 'Ascaris lumbricoides', 'Capsule Endoscopy', 'Female', 'Humans', 'Intestine, Small', 'Male', 'Middle Aged', 'Retrospective Studies'] | 24,812,868 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['C01.610.335.508.700.100.070'], ['B01.050.500.500.294.400.500.100.108.425'], ['E01.370.388.250.250.250.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.36... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Varieties of misdiagnosis in ASD: an illustrative case series. | The relationship between autism spectrum disorders (ASD) and psychotic disorders (PD) is a focus of continued interest. There are substantial conceptual and clinical difficulties associated with diagnosing comorbid PD in individuals who have ASD. In this case series, we report on five cases where adolescents with previ... | ['Adolescent', 'Child Development Disorders, Pervasive', 'Diagnostic Errors', 'Female', 'Humans', 'Male', 'Psychotic Disorders', 'Young Adult'] | 25,218,849 | [['M01.060.057'], ['F03.625.164'], ['E01.354', 'N02.421.450.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.700.675'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Listening to native patients. Changes in physicians' understanding and behaviour. | OBJECTIVE: To discover how physicians develop an understanding of Native patients and communities that enables them to communicate better with these patients.DESIGN: Qualitative method of in-depth interviews.SETTING: Native communities across Canada.PARTICIPANTS: Ten non-Native physicians providing primary care to Nati... | ['Adult', 'Canada', 'Communication Barriers', 'Cultural Characteristics', 'Humans', 'Indians, North American', 'Interviews as Topic', 'Physician-Patient Relations'] | 12,449,549 | [['M01.060.116'], ['Z01.107.567.176'], ['L01.143.230'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.600'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01.829.401.650.675', 'N05.300.660.625']] | ['Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Habituation and recovery of a slow negative wave of the event-related brain potential. | This study is concerned with the question of whether the late, slow negative wave 2 (SNW2) component of the event-related brain potential is a component of the orienting response (OR). As habituation of the SNW2 would be an argument for such a link with the OR, it was investigated using a variant of the classical repet... | ['Acoustic Stimulation', 'Adolescent', 'Adult', 'Brain', 'Electrocardiography', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Galvanic Skin Response', 'Habituation, Psychophysiologic', 'Humans', 'Male', 'Orientation'] | 11,850,088 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['F02.463.425.39... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genotyping and macrolide resistance of Mycoplasma pneumoniae identified in children with community-acquired pneumonia in Medell?n, Colombia. | OBJECTIVES: The aim of this study was to describe the genotypes and the main characteristics of community-acquired pneumonia (CAP) caused by Mycoplasma pneumoniae in hospitalized children in Medell?n and neighboring municipalities during the period 2011-2012.METHODS: The M. pneumoniae genotype was determined by PCR and... | ['Adolescent', 'Anti-Bacterial Agents', 'Child', 'Child, Preschool', 'Colombia', 'Community-Acquired Infections', 'Drug Resistance, Bacterial', 'Female', 'Genotype', 'Humans', 'Macrolides', 'Male', 'Molecular Typing', 'Mutation', 'Mycoplasma pneumoniae', 'Pneumonia, Mycoplasma', 'Polymerase Chain Reaction', 'RNA, Ribos... | 29,155,089 | [['M01.060.057'], ['D27.505.954.122.085'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.757.284'], ['C01.234'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['E01.370.225.875.150.125.457... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reliable Attention Network Scores and Mutually Inhibited Inter-network Relationships Revealed by Mixed Design and Non-orthogonal Method. | The attention system can be divided into alerting, orienting, and executive control networks. The efficiency and independence of attention networks have been widely tested with the attention network test (ANT) and its revised versions. However, many studies have failed to find effects of attention network scores (ANSs)... | ['Adolescent', 'Adult', 'Attention', 'Executive Function', 'Female', 'Humans', 'Male', 'Orientation', 'Reaction Time', 'Young Adult'] | 25,997,025 | [['M01.060.057'], ['M01.060.116'], ['F02.830.104.214'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.058.577', 'F02.830.606'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pertussis in adults. A study in an Italian population with chronic cough. | OBJECTIVE: Pertussis is commonly regarded as a disease of children but a number of clinical studies show that quite often it occurs in older children and adults, too. The purpose of the present study was to determine the prevalence of Bordetella pertussis infection in an Italian population of adults with persistent non... | ['Adolescent', 'Adult', 'Antigens, Bacterial', 'Bordetella Infections', 'Bordetella pertussis', 'Chronic Disease', 'Cough', 'Female', 'Humans', 'Italy', 'Male', 'Middle Aged'] | 12,814,036 | [['M01.060.057'], ['M01.060.116'], ['D23.050.161'], ['C01.150.252.400.143'], ['B03.440.400.425.115.425.600', 'B03.660.075.090.344.425.600'], ['C23.550.291.500'], ['C08.618.248', 'C23.888.852.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Evaluation of a flow cytometric fluorescence quenching assay of phagocytosis of sensitized sheep erythrocytes by polymorphonuclear leukocytes. | A number of reports have been published describing phagocytosis assays for flow cytometric analysis. In some of these, the fluorescence quenching technique has been used to discriminate between adherent and ingested particles. In this report, we have evaluated the efficacy of a quantitative fluorescence quenching techn... | ['Animals', 'Cells, Cultured', 'Erythrocytes', 'Fibroblasts', 'Flow Cytometry', 'Fluorescent Dyes', 'Gentian Violet', 'Humans', 'Mice', 'Neutrophils', 'Organic Chemicals', 'Phagocytosis', 'Sheep', 'Trypan Blue'] | 7,875,036 | [['B01.050'], ['A11.251'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.329.228'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D02.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of fibrinolysis in the pericardial cavity during cardiopulmonary bypass. | The clotting and fibrinolytic systems are activated by tissue factor and by tissue-type plasminogen activator in the pericardial cavity, where the thrombogenicity is greater than that of the surface of modern extracorporeal circuits. This local activation may have consequences for the systemic activation processes duri... | ['Blood Coagulation Factors', 'Cardiopulmonary Bypass', 'Fibrinolysis', 'Heparin', 'Humans', 'Middle Aged', 'Pericardium', 'Platelet Activation'] | 8,231,204 | [['D12.776.124.125', 'D23.119'], ['E04.292.413'], ['G09.188.390.150.390'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.795', 'A10.615.789.470'], ['G09.188.390.600']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Novel visual system homeobox 1 gene mutations in Turkish patients with keratoconus. | The aim of this study was to screen the visual system homeobox 1 (VSX1) gene in Turkish patients with keratoconus (KC). The patient group consisted of 44 patients who had undergone corneal transplant surgery before the age of 30, for advanced and rapidly progressive KC. The control group comprised 250 healthy individua... | ['Adult', 'Amino Acid Sequence', 'Case-Control Studies', 'Computational Biology', 'DNA Mutational Analysis', 'Eye Proteins', 'Female', 'Homeodomain Proteins', 'Humans', 'Keratoconus', 'Male', 'Mutation', 'Turkey', 'Young Adult'] | 27,819,732 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['H01.158.273.180', 'L01.313.124'], ['E05.393.760.700.300'], ['D12.776.306'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.204.627'], ['G05.365.590'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Nomifensine vs. imipramine in depressed inpatients. | In a double-blind random assignment study, nomifensine was compared to imipramine in a population of depressed male inpatients (N = 36; ages 22-56 years). Nomifensine and imipramine in doses of 100-150 mg/day were found to be comparable over the 4-week treatment period on the Hamilton Depression Rating Scale and Clinic... | ['Adult', 'Akathisia, Drug-Induced', 'Clinical Trials as Topic', 'Depressive Disorder', 'Double-Blind Method', 'Headache', 'Hospitalization', 'Humans', 'Imipramine', 'Isoquinolines', 'Male', 'Middle Aged', 'Nomifensine', 'Personality Inventory', 'Psychiatric Status Rating Scales', 'Random Allocation', 'Sleep', 'Xerosto... | 6,370,978 | [['M01.060.116'], ['C10.228.662.037', 'C10.720.075', 'C23.888.592.350.600.500', 'C25.100.249', 'C25.723.705.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F03.600.300'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C23.888.592.612.441']... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antiviral Activity of Aspalathus linearis against Human Influenza Virus. | Influenza A viruses are responsible for annual epidemics and occasional pandemics, which cause significant morbidity and mortality. The limited protection offered by influenza vaccination, and the emergence of drug-resistant influenza strains, highlight the urgent need for the development of novel anti-influenza drugs.... | ['Antiviral Agents', 'Aspalathus', 'Humans', 'Influenza, Human', 'Orthomyxoviridae', 'Plant Extracts', 'Virus Replication'] | 30,520,604 | [['D27.505.954.122.388'], ['B01.650.940.800.575.912.250.401.082'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['B04.820.480.968'], ['D20.215.784.500', 'D26.667'], ['G06.920.925']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Childhood adrenoleukodystrophy. Failure of intensive immunosuppression to arrest neurologic progression. | Cyclophosphamide in a dosage of 350 to 700 mg/m2/d was administered for five to 11 days to four patients with childhood adrenoleukodystrophy (ALD) and to one patient with the adult cerebral form of the disease. The rate of neurologic progression in the four patients with childhood ALD did not differ from that of 167 un... | ['Adrenoleukodystrophy', 'Adult', 'Brain', 'Child', 'Clinical Trials as Topic', 'Coma', 'Cyclophosphamide', 'Diffuse Cerebral Sclerosis of Schilder', 'Humans', 'Immunosuppressive Agents', 'Male', 'Nervous System Diseases', 'Radiography', 'Time Factors'] | 3,293,554 | [['C10.228.140.163.100.084', 'C10.228.140.163.100.362.250', 'C10.228.140.695.625.250', 'C10.314.400.250', 'C10.597.606.360.455.124', 'C16.320.322.500.124', 'C16.320.400.525.124', 'C16.320.565.189.084', 'C16.320.565.189.362.250', 'C16.320.565.663.100', 'C18.452.132.100.084', 'C18.452.132.100.362.250', 'C18.452.648.189.0... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of netilmicin regimens on the activities of ceftazidime-netilmicin combinations against Pseudomonas aeruginosa in an in vitro pharmacokinetic model. | The antibacterial activities of ceftazidime and netilmicin were studied in a two-compartment in vitro model. Pseudomonas aeruginosa cultures were exposed to changing drug concentrations that mimic human pharmacokinetics. Netilmicin alone reduced the numbers of organisms in cultures of the susceptible strains by more th... | ['Ceftazidime', 'Drug Combinations', 'Drug Synergism', 'Gentamicins', 'Humans', 'Kinetics', 'Microbial Sensitivity Tests', 'Models, Biological', 'Netilmicin', 'Pseudomonas aeruginosa', 'Time Factors'] | 3,929,682 | [['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['D26.310'], ['G07.690.773.968.477'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E05.599.395'], ['D09.40... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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