Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Adhesiveness of beta5 integrin variant lacking FNK767-769 is similar to that of the prototype containing FNKFNK764-769. | Little is known about the functions of two different beta5 integrins: repeated-FNK (FNKFNK764-769) and single-FNK (FNK764-766) amino acid sequences in the cytoplasmic domain. We examined whether they occurred as germ line mutations or somatic mutations associated with neoplastic transformation, and whether there were f... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'CHO Cells', 'Cell Adhesion', 'Cell Line, Tumor', 'Cell Proliferation', 'Colonic Neoplasms', 'Cricetinae', 'Cricetulus', 'Genetic Variation', 'Germ-Line Mutation', 'Humans', 'Integrin beta Chains', 'Membrane Proteins', 'Molecular Sequence Data', 'Polymorphism, Genetic... | 15,979,906 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.200', 'A11.436.155'], ['G04.022'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.41... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Influence of patient costs and requests on emergency physician decisionmaking. | STUDY OBJECTIVES: We examine emergency physician knowledge of, attitudes about, and responses to patient cost-sharing in the emergency department (ED).METHODS: A convenience sample of emergency physicians from an integrated delivery system completed a questionnaire including self-report questions about knowledge of and... | ['Attitude of Health Personnel', 'California', 'Cost Sharing', 'Cross-Sectional Studies', 'Decision Making', 'Emergency Medicine', 'Female', 'Humans', 'Male', 'Physician-Patient Relations', 'Surveys and Questionnaires'] | 18,439,723 | [['F01.100.050', 'N05.300.100'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N03.219.151.170', 'N03.219.521.576.090'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['H02.403.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650.675... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
In vivo neuroprotective effects of peripheral kynurenine on acute neurotoxicity induced by glutamate in rat cerebral cortex. | N-methyl-D-aspartate (NMDA) receptors play a crucial role in Glutamate (L-Glu) neurotoxicity. To evaluate the effects of astrocyte-derived tryptophan metabolite kynurenic acid (KYNA), on L-Glu neurotoxicity, adult male rats were pretreated with Kynurenine (KYN) which is a precursor of KYNA, at a dose of 30 mg or 300 mg... | ['Animals', 'Catalase', 'Cerebral Cortex', 'Flow Cytometry', 'Glutamic Acid', 'Glutathione', 'Glutathione Reductase', 'Kynurenine', 'Lipid Peroxidation', 'Male', 'Neuroprotective Agents', 'Rats', 'Rats, Sprague-Dawley', 'Reactive Oxygen Species', 'Superoxide Dismutase'] | 20,035,383 | [['B01.050'], ['D08.811.682.732.332'], ['A08.186.211.200.885.287.500'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D12.644.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictors of depression among refugees from Vietnam: a longitudinal study of new arrivals. | The present study examined the impact of prearrival traumatic experiences and sociodemographic characteristics on future depression among Vietnamese and Chinese refugees from Vietnam. This is a longitudinal study of newly arrived refugees from Vietnam undergoing a mandatory health screening. A stratified consecutive sa... | ['Adult', 'Age Factors', 'China', 'Depressive Disorder', 'Ethnic Groups', 'Female', 'Humans', 'Language', 'Life Change Events', 'Longitudinal Studies', 'Male', 'Probability', 'Psychiatric Status Rating Scales', 'Refugees', 'United States', 'Vietnam', 'Warfare'] | 9,040,532 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.252.474.164'], ['F03.600.300'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F01.829.458.410'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'],... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Translational regulation of rotavirus gene expression. | Rotavirus mRNAs are transcribed from 11 genomic dsRNA segments within a subviral particle. The mRNAs are extruded into the cytoplasm where they serve as mRNA for protein synthesis and as templates for packaging and replication into dsRNA. The molecular steps in the replication pathway that regulate the levels of viral ... | ['Animals', 'Antigens, Viral', 'Capsid Proteins', 'Cattle', 'Cell Line', 'Gene Expression Regulation, Viral', 'Molecular Sequence Data', 'Polyribosomes', 'Protein Biosynthesis', 'RNA Processing, Post-Transcriptional', 'RNA, Messenger', 'Rotavirus', 'Viral Nonstructural Proteins'] | 12,560,571 | [['B01.050'], ['D23.050.327'], ['D12.776.964.970.600.550'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['G05.308.385'], ['L01.453.245.667'], ['A11.284.430.214.190.875.811.740'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['G02.111.760', 'G03.839', 'G05.308.700'], ['D13.444.735.544'], ['B04.820.22... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Nucleotide substitutions in the rpoB gene leading to rifampicin resistance of E. coli RNA polymerase]. | Three new rif-r-mutations, obtained independently, were localized in the rpoB gene coding for the beta-subunit of DNA-dependent RNA polymerase of E. coli. Two of them led to identical Asp(516)-Asn amino acid substitution with relatively low resistance of corresponding E. coli strains to rifampicin. The third mutation a... | ['Base Sequence', 'DNA-Directed RNA Polymerases', 'Drug Resistance, Microbial', 'Escherichia coli', 'Genes, Bacterial', 'Mutation', 'Rifampin'] | 6,385,989 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.696.445.735.270'], ['G06.225', 'G07.690.773.984.269'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.365.590'], ['D03.633.400.811.700', 'D04.34... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Conformational stability of Helicobacter pylori flavodoxin: fit to function at pH 5. | Flavodoxin is an essential protein for Helicobacter pylori, a pathogen living in the very acidic environment of the gastric tract and responsible for several diseases. We report the conformational stability of the protein in neutral and acidic pH. The apoprotein remains native between pH 12 and 5 and adopts a monomeric... | ['Apoproteins', 'Bacterial Proteins', 'Circular Dichroism', 'Drug Stability', 'Flavodoxin', 'Helicobacter pylori', 'Histidine', 'Hydrogen-Ion Concentration', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Conformation', 'Protein Folding', 'Recombinant Proteins', 'Solubility', 'Spectrum Analysis', 'Thermodynamics'... | 17,998,211 | [['D12.776.070'], ['D12.776.097'], ['E05.196.867.151'], ['E05.916.330'], ['D12.776.097.400', 'D12.776.331.400'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['D12.125.072.329', 'D12.125.142.308'], ['G02.300'], ['E05.196.867.519.550'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688'], ['D12.776.828'], ['G... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondrial DNA levels in fat and blood cells from patients with lipodystrophy or peripheral neuropathy and the effect of 90 days of high-dose coenzyme Q treatment: a randomized, double-blind, placebo-controlled pilot study. | BACKGROUND: Mitochondrial toxicity can be induced by reverse-transcriptase inhibitors, and an association between levels of mitochondrial DNA (mtDNA) per cell and lipodystrophy, peripheral neuropathy, and HIV infection per se has been suggested. Studies aimed at increasing the oxidative capacity in HIV-infected patient... | ['Adipocytes', 'Adipose Tissue', 'Adult', 'Aged', 'DNA, Mitochondrial', 'Double-Blind Method', 'Female', 'HIV Infections', 'HIV-Associated Lipodystrophy Syndrome', 'Humans', 'Male', 'Middle Aged', 'Neutrophils', 'Peripheral Nervous System Diseases', 'Reverse Transcriptase Inhibitors', 'Ubiquinone'] | 15,494,915 | [['A11.329.114'], ['A10.165.114'], ['M01.060.116'], ['M01.060.116.100'], ['D13.444.308.283.225'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.25... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Age related microsatellite instability in T cells from healthy individuals. | Many immune functions decline with age and may jeopardize the elderly, as illustrated, for example by the significantly higher mortality rate from influenza in old age. Although innate and humoral immunity are affected by aging, it is the T cell compartment, which manifests most alterations. The mechanisms behind these... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Base Pair Mismatch', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cellular Senescence', 'DNA Methylation', 'DNA Repair', 'Humans', 'Microsatellite Repeats', 'Middle Aged', 'Promoter Regions, Genetic', 'T-Lymphocytes'] | 15,050,284 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['G05.365.590.060'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G04.043'], ['G02.1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Calculation of the number of terminally ill patients through their use of opioid analgesics and tumor mortality]. | OBJECTIVE: To find the number of patients in terminal care in Madrid Health District 3.DESIGN: Ecological, descriptive study.SETTING: Eleven Health Districts. Madrid, Spain, 2002.MAIN MEASUREMENTS: Two models were used to calculate the number of patients in terminal care and were compared with data from the Primary Car... | ['Analgesics, Opioid', 'Drug Utilization', 'Humans', 'Models, Statistical', 'Neoplasms', 'Terminal Care', 'Terminally Ill'] | 16,527,115 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['N04.452.706.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['C04'], ['E02.760.905', 'N02.421.585.905... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of 13-cis-retinoic acid on survival of patients with myelodysplastic syndrome. | A randomised therapeutic trial of 13-cis-retinoic acid was carried out in 70 patients with myelodysplastic syndrome having 5% or fewer marrow blast cells. Among non-sideroblastic patients the 1-year survival in the treated group was 77%, compared with 36% in the control group. There were too few deaths among patients w... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anemia, Sideroblastic', 'Clinical Trials as Topic', 'Female', 'Humans', 'Isomerism', 'Isotretinoin', 'Male', 'Middle Aged', 'Myelodysplastic Syndromes', 'Random Allocation', 'Tretinoin'] | 2,882,180 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C15.378.071.419', 'C15.378.190.625.070'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.685', 'G02.607.445'], ['D02.455.326.271.665.202.495.325', 'D02.455.426... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acoustic vowel reduction in Creek: effects of distinctive length and position in the word. | Eight speakers (4 male and 4 female) of the Muskogee dialect of Creek pronounced a set of words illustrating the vowels and diphthongs of Creek. These recordings were analyzed acoustically and data on vowel duration and vowel formant frequencies are presented in this paper. The ratio of the durations of dictinctively l... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Language', 'Male', 'Middle Aged', 'Phonetics', 'Speech', 'Speech Acoustics', 'Speech Production Measurement'] | 11,096,370 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['M01.060.116.630'], ['L01.559.598.518'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['G11.561.812.650', 'G11.561.820'], ['E01.370.760']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Promoters and processing sites within the transforming region of bovine papillomavirus type 1. | The mRNAs present in bovine papillomavirus type 1 (BPV-1)-transformed C127 cells were studied by primer extension. The results show that two internal promoters are present in the E region of BPV-1 in addition to the previously identified promoter at coordinate 1 (H. Ahola, A. Stenlund, J. Moreno-L?pez, and U. Pettersso... | ['Base Sequence', 'Bovine papillomavirus 1', 'DNA', 'Gene Expression Regulation', 'Papillomaviridae', 'Poly A', 'Promoter Regions, Genetic', 'RNA Caps', 'RNA, Messenger', 'RNA, Viral'] | 2,884,331 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B04.280.210.655.200.100', 'B04.613.204.655.200.100'], ['D13.444.308'], ['G05.308'], ['B04.280.210.655', 'B04.613.204.655'], ['D13.695.578.550.500'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['D03.633.100.759.646.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Involvement of silent synapses in the induction of long-term potentiation and long-term depression in neocortical and hippocampal neurons. | Changes in the latency of small excitatory postsynaptic potentials were observed in association with induction of long-term modifications of synaptic transmission in slices of rat neocortex and guinea-pig hippocampus. After potentiation response latency decreased in 3/10 cases in the neocortex and in 6/24 cases in the ... | ['Animals', 'Cerebral Cortex', 'Hippocampus', 'Long-Term Potentiation', 'Rats', 'Reaction Time', 'Synapses'] | 8,865,185 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G11.561.638.350'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['A08.850', 'A11.284.149.165.420.780']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diffuse intrapulmonary malignant mesothelioma masquerading as interstitial lung disease: a distinctive variant of mesothelioma. | Malignant mesothelioma typically encases lungs as a thick rind, while relatively sparing lung parenchyma. We describe an unusual presentation of mesothelioma characterized by diffuse intrapulmonary growth, with absent or inconspicuous pleural involvement, clinically simulating interstitial lung disease (ILD). We identi... | ['Aged', 'Diagnosis, Differential', 'Humans', 'Immunohistochemistry', 'Lung Diseases, Interstitial', 'Lung Neoplasms', 'Male', 'Mesothelioma', 'Middle Aged'] | 23,797,722 | [['M01.060.116.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Argosomes: a potential vehicle for the spread of morphogens through epithelia. | The formation of morphogen gradients is essential for tissue patterning. Morphogens are released from producing cells and spread through adjacent tissue; paradoxically, however, many morphogens, including Wingless, associate tightly with the cell membrane. Here, we describe a novel cell biological mechanism that disper... | ['Animals', 'Biomarkers', 'Cell Membrane Structures', 'Drosophila Proteins', 'Drosophila melanogaster', 'Endosomes', 'Epithelium', 'Green Fluorescent Proteins', 'Heparin Lyase', 'Indicators and Reagents', 'Luminescent Proteins', 'Models, Biological', 'Morphogenesis', 'Proto-Oncogene Proteins', 'Transport Vesicles', 'Wn... | 11,551,510 | [['B01.050'], ['D23.101'], ['A11.284.149.165'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['A11.284.430.214.190.875.190.880.337'], ['A10.272'], ['D12.776.532.265'], ['D08.811.520.241.700.512'], ['D27.720.470.410'], ['D12.776.532'], ['E05.599.395'], ['G07.345.500'], ['D12.776.624.664.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The use of artificial neural networks in evaluation of posturographic data]. | BACKGROUND: Posturography methods have been applied in clinical neurootology to evaluate the equilibrium function of patients. Methods of statistical analysis play an important role for improving data processing and to support the interpretation of the results. In contrast to conventional statistics, artificial neural ... | ['Alcoholic Beverages', 'Diagnosis, Computer-Assisted', 'Ethanol', 'Fourier Analysis', 'Humans', 'Meniere Disease', 'Neural Networks, Computer', 'Neural Pathways', 'Postural Balance', 'Reference Values', 'Sensory Deprivation', 'Signal Processing, Computer-Assisted', 'Spinal Cord', 'Vestibular Function Tests', 'Vestibul... | 21,110,291 | [['G07.203.100.100', 'J02.200.100'], ['E01.158', 'L01.313.500.750.100.158'], ['D02.033.375'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.568.217.500'], ['G17.485', 'L01.224.050.375.605'], ['A08.612'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.690', 'G... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Anatomical and electrophysiological identification of motoneurones supplying the cat retractor bulbi muscle. | Motoneurones innervating the retractor bulbi muscle in the cat have been identified by retrograde labelling with horseradish peroxidase, by intracellular recording and by intracellular staining with horseradish peroxidase. Their somata are found in an accessory abducens nucleus, analogous to that described in some othe... | ['Abducens Nerve', 'Animals', 'Axons', 'Brain Stem', 'Cats', 'Electric Stimulation', 'Evoked Potentials', 'Horseradish Peroxidase', 'Motor Neurons', 'Oculomotor Muscles', 'Reflex'] | 421,760 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improving the cellular invasion into PHEMA sponges by incorporation of the RGD peptide ligand: the use of copolymerization as a means to functionalize PHEMA sponges. | A monomer that contained the RGD ligand motif was synthesized and copolymerized with 2-hydroxyethyl methacrylate using polymerization-induced phase separation methods to form poly(2-hydroxyethyl methacrylate)-based hydrogel sponges. The sponges had morphologies of aggregated polymer droplets and interconnected pores, t... | ['Biocompatible Materials', 'Cell Adhesion', 'Cells, Cultured', 'Epithelial Cells', 'Humans', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Ligands', 'Microscopy, Electron, Transmission', 'Oligopeptides', 'Polyhydroxyethyl Methacrylate'] | 24,094,205 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G04.022'], ['A11.251'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.455.250.700.485', 'D05.750.219.500', 'D05.750.741.485', 'D20.280.320.609.500', 'D25.720.532.500', 'D25.720.741.485', 'D26.255.165.320.375.375', 'J01.637.051.720.584.500',... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Duloxetine and pregabalin for pain management in multiple rheumatic diseases associated with fibromyalgia. | The fibromyalgia syndrome (FMS) is characterized by chronic and widespread musculoskeletal pain and soreness accompanied by sleep disorders, chronic fatigue and affective disorders. FMS is often associated with other forms of immuno-rheumatic diseases. Although FMS pathophysiology is still not fully understood, a numbe... | ['Analgesics', 'Comorbidity', 'Duloxetine Hydrochloride', 'Female', 'Fibromyalgia', 'Humans', 'Middle Aged', 'Pregabalin', 'Rheumatic Diseases', 'Thiophenes', 'gamma-Aminobutyric Acid'] | 23,126,475 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['N05.715.350.225', 'N06.850.490.687'], ['D02.886.778.260', 'D03.383.903.260'], ['C05.651.324', 'C05.799.321', 'C10.668.491.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.241.081.114.500.350.500', 'D12.125.190.350.450'], ['C05.799'... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Leukemia inhibitory factor ameliorates muscle fiber degeneration in the mdx mouse. | Although the muscles of the mdx mouse lack dystrophin, the protein absent in muscles of humans affected with Duchenne muscular dystrophy (DMD), the only mdx muscle to degenerate in a manner similar to those of DMD boys is the diaphragm. We have previously shown that leukemia inhibitory factor (LIF) is a trauma factor t... | ['Animals', 'Cell Size', 'Diaphragm', 'Growth Inhibitors', 'Infusion Pumps, Implantable', 'Interleukin-6', 'Leukemia Inhibitory Factor', 'Lymphokines', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred mdx', 'Muscle Contraction', 'Muscle Fatigue', 'Muscle Fibers, Skeletal', 'Muscular Atrophy', 'Muscular Dystrophy, Animal', '... | 11,054,748 | [['B01.050'], ['G04.325'], ['A02.633.567.900.300'], ['D27.505.696.377.450'], ['E07.505.254', 'E07.858.082.505.254'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D12.644.276.374.470', 'D12.776.467.374.470', 'D23.529.374.470'], ['D12.644.276.374.480', 'D12.776.467.374.480', 'D23.529.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Late Results of Half-Turned Truncal Switch Operation for Transposition of the Great Arteries. | BACKGROUND: Conventional Rastelli, Lecompte, and Nikaidoh operations are accepted as standard techniques for complete transposition of the great arteries (TGA) with left ventricular outflow tract (LVOT) obstruction. These operations show serious drawbacks, however, including postoperative obstruction of both ventricula... | ['Cardiac Surgical Procedures', 'Child, Preschool', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Reconstructive Surgical Procedures', 'Recovery of Function', 'Retrospective Studies', 'Risk Assessment', 'Survival Analysis', 'Transposition of Great Vessels', 'Treatment Outcome'] | 30,031,843 | [['E04.100.376', 'E04.928.220'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E04.680'], ['G16.757'], ['E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Should influenza vaccination be mandatory for healthcare staff? | Emeritus Professor Alan Glasper, from the University of Southampton, discusses government concerns about the low uptake of flu vaccination among frontline healthcare staff. | ['Health Personnel', 'Humans', 'Influenza Vaccines', 'Mandatory Programs', 'State Medicine', 'United Kingdom'] | 31,972,120 | [['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['I01.880.604.622', 'N03.706.657', 'N04.452.521'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
AIDS alarm: a case study. | Acquired Immune Deficiency Syndrome (AIDS) has made a wide impact not limited to those persons who have or are likely to contact it. A case history of a man with a near-delusional belief he had AIDS is presented to exemplify the individual issues that concern about AIDS may raise. Thorough exploration of the dynamic in... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Attitude to Health', 'Depressive Disorder', 'Humans', 'Male', 'Referral and Consultation', 'Somatoform Disorders'] | 3,409,157 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.758.849'], ['F03.875']] | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exogenous nucleosides promote the completion of MoMLV DNA synthesis in G0-arrested Balb c/3T3 fibroblasts. | We studied Moloney murine leukemia virus replication in newly infected Balb c/3T3 cells brought to the G0 phase by serum depletion. Using the polymerase chain reaction method, we showed that Moloney murine leukemia virus can be efficiently internalized in nonproliferating fibroblasts, although reverse transcription of ... | ['Animals', 'Base Sequence', 'Cytidine', 'DNA, Viral', 'Fibroblasts', 'Hydroxyurea', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Moloney murine leukemia virus', 'Nucleosides', 'Pyrimidine Nucleotides', 'RNA-Directed DNA Polymerase', 'Resting Phase, Cell Cycle', 'Transcription, Genetic', 'Virus Replicatio... | 7,510,441 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.383.742.680.245', 'D13.570.685.245', 'D13.570.800.286'], ['D13.444.308.568'], ['A11.329.228'], ['D02.065.950.395'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Arithmetic memory networks established in childhood are changed by experience in adulthood. | Adult bilinguals show stronger access to multiplication tables when using the language in which they learned arithmetic during childhood (LA+) than the other language (LA-), implying language-specific encoding of math facts. However, most bilinguals use LA+ throughout their life, confounding the impact of encoding and ... | ['Adult', 'Evoked Potentials', 'Female', 'Humans', 'Male', 'Mathematical Concepts', 'Memory', 'Middle Aged', 'Multilingualism', 'Problem Solving', 'Teaching'] | 25,445,361 | [['M01.060.116'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17'], ['F02.463.425.540'], ['M01.060.116.630'], ['L01.559.423.452'], ['F02.463.425.725', 'F02.463.785.810'], ['I02.903']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Transient expression of wild-type and mutant glucocerebrosidases in hybrid vaccinia expression system. | Gaucher disease, the most prevalent lysosomal storage disease, is characterised by a significant phenotypic variation caused by more than 150 mutations. In order to verify pathogenicity of mutations found in the Czech Gaucher population, the vaccinia expression system was used. The wild-type human beta-glucocerebrosida... | ['Cloning, Molecular', 'Gaucher Disease', 'Genetic Vectors', 'Glucosylceramidase', 'HeLa Cells', 'Humans', 'Mutagenesis, Site-Directed', 'Mutation', 'Vaccinia virus'] | 12,734,541 | [['E05.393.220'], ['C10.228.140.163.100.435.825.400', 'C16.320.565.189.435.825.400', 'C16.320.565.398.641.803.441', 'C16.320.565.595.554.825.400', 'C18.452.132.100.435.825.400', 'C18.452.584.687.803.441', 'C18.452.648.189.435.825.400', 'C18.452.648.398.641.803.441', 'C18.452.648.595.554.825.400'], ['G05.360.337'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three-month stability of the CogState brief battery in healthy older adults, mild cognitive impairment, and Alzheimer's disease: results from the Australian Imaging, Biomarkers, and Lifestyle-rate of change substudy (AIBL-ROCS). | Large prospective studies of Alzheimer's disease (AD) have sought to understand the pathological evolution of AD and factors that may influence the rate of disease progression. Estimates of rates of cognitive change are available for 12 or 24 months, but not for shorter time frames (e.g., 3 or 6 months). Most clinical ... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Analysis of Variance', 'Aniline Compounds', 'Association Learning', 'Australia', 'Case-Control Studies', 'Cognitive Dysfunction', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Neuro... | 23,552,802 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D02.092.146'], ['F02.463.425.069.296'], ['Z01.639.100', 'Z01.678.10... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cancer chemotherapy model using autochthonous large bowel cancer in rats. | Chemotherapy of methylnitrosourea-induced autochthonous large bowel cancer in rats, which is similar to that in man, was studied to evaluate the intrarectal administration or topical application of chemotherapeutic agents. Rats with large bowel tumors confirmed by endoscopic examination received an intrarectal instilla... | ['Administration, Topical', 'Animals', 'Drug Evaluation, Preclinical', 'Female', 'Fluorouracil', 'Intestinal Neoplasms', 'Methylnitrosourea', 'Neoplasms, Experimental', 'Nitrosourea Compounds', 'Rats', 'Semustine'] | 669,141 | [['E02.319.267.120'], ['B01.050'], ['E05.290.750', 'E05.337.550'], ['D03.383.742.698.875.404'], ['C04.588.274.476.411', 'C06.301.371.411', 'C06.405.249.411', 'C06.405.469.491'], ['D02.065.950.594.490', 'D02.654.692.480'], ['C04.619', 'E05.598.500.496'], ['D02.065.950.594', 'D02.654.692'], ['B01.050.150.900.649.313.992.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Involvement of lipid peroxidation in the degradation of a non-phenolic lignin model compound by manganese peroxidase of the litter-decomposing fungus Stropharia coronilla. | Culture liquids of the litter-decomposing basidiomycete Stropharia coronilla showed pro-oxidant activity promoting the peroxidation of linoleic acid. This activity depended on the presence of manganese peroxidase (MnP) in the fungal culture. Pro-oxidant activity maxima coincided with maximum MnP activities during the s... | ['Basidiomycota', 'Culture Media', 'Hydrolysis', 'Lignin', 'Lipid Peroxidation', 'Peroxidases', 'Reactive Oxygen Species'] | 15,796,893 | [['B01.300.179'], ['D27.720.470.305', 'E07.206'], ['G02.380'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['G02.111.515', 'G03.295.531.587'], ['D08.811.682.732'], ['D01.339.431', 'D01.650.775']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Different requirements for ó Region 4 in BvgA activation of the Bordetella pertussis promoters P(fim3) and P(fhaB). | Bordetella pertussis BvgA is a global response regulator that activates virulence genes, including adhesin-encoding fim3 and fhaB. At the fhaB promoter, P(fhaB), a BvgA binding site lies immediately upstream of the -35 promoter element recognized by Region 4 of the ó subunit of RNA polymerase (RNAP). We demonstrate tha... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Binding Sites', 'Bordetella pertussis', 'DNA, Bacterial', 'DNA-Directed RNA Polymerases', 'Hydroxyl Radical', 'Molecular Sequence Data', 'Mutation', 'Promoter Regions, Genetic', 'Sequence Homology, Amino Acid', 'Sequence Homology, Nucleic Acid', 'Transcrip... | 21,536,048 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['B03.440.400.425.115.425.600', 'B03.660.075.090.344.425.600'], ['D13.444.308.212'], ['D08.811.913.696.445.735.270'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mixed infections of Marek's disease and reticuloendotheliosis viruses in layer flocks in Argentina. | The presence of reticuloendotheliosis virus (REV) was examined in flocks affected with Marek's disease (MD). Sera were positive to REV antibodies by agar gel precipitation. However, these findings were not conclusive since fowlpox vaccines can have REV fragments or the whole genome inserted. Frozen sections from tumors... | ['Animals', 'Argentina', 'Cells, Cultured', 'Chick Embryo', 'Chickens', 'Coinfection', 'Female', 'Fluorescent Antibody Technique', 'Lymphocytes', 'Mardivirus', 'Marek Disease', 'Poultry Diseases', 'Reticuloendotheliosis virus', 'Retroviridae Infections', 'Tumor Virus Infections'] | 23,901,777 | [['B01.050'], ['Z01.107.757.077'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['C01.218'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A11.118.637.555.567', 'A... | ['Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Assessment of the real-world safety profile of vedolizumab using the United States Food and Drug Administration adverse event reporting system. | Vedolizumab is the first gut-selective integrin blocker indicated for patients with Crohn's disease (CD) and ulcerative colitis (UC). This study aimed to examine the adverse events (AEs) profile of vedolizumab compared to anti-tumor necrosis factors (anti-TNFs) indicated for CD and UC using the FDA Adverse Event Report... | ['Adult', 'Adverse Drug Reaction Reporting Systems', 'Antibodies, Monoclonal, Humanized', 'Female', 'Humans', 'Male', 'Tumor Necrosis Factor-alpha', 'United States', 'United States Food and Drug Administration'] | 31,800,627 | [['M01.060.116'], ['E05.337.800.120', 'N02.421.668.320.120'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.500.800', 'D12.644.276.374.750.626', 'D12.776.124.900', 'D12.776.395.930', 'D12.776.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes. | Alteration of nucleosomes by ATP-dependent remodeling complexes represents a critical step in the regulation of transcription. The human SWI/SNF (hSWI/SNF) family is composed of complexes that contain either Brg1 or hBrm as the central ATPase; however, these separate complexes have not been compared functionally. Here ... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Blotting, Western', 'Cell Line', 'Chromatin', 'DNA Helicases', 'Epitopes', 'Histone Deacetylases', 'Humans', 'Mi-2 Nucleosome Remodeling and Deacetylase Complex', 'Nuclear Proteins', 'Nucleosomes', 'Protein Binding', 'Sin3 Histone Deacetylase and Corepressor Comp... | 11,238,380 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D08.811.277.040.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcatheter hepatocyte transplantation: preclinical studies of anatomic consequences in the portal vascular bed. | RATIONALE AND OBJECTIVES: Intrasplenic transplantation deposits hepatocytes in host hepatic sinusoids with amelioration of chronic liver failure and genetic deficiency states. Because portal resistance can be altered by intrasinusoidal transplanted cells, we examined whether hepatocyte recipients would develop deleteri... | ['Animals', 'Cell Separation', 'Collateral Circulation', 'Dipeptidyl-Peptidases and Tripeptidyl-Peptidases', 'Hemodynamics', 'Histocytochemistry', 'Hypertension, Portal', 'Liver', 'Liver Transplantation', 'Portal System', 'Rats', 'Rats, Inbred F344', 'Rats, Mutant Strains', 'Rats, Sprague-Dawley', 'Spleen', 'Time Facto... | 9,419,491 | [['B01.050'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['G09.330.100.248'], ['D08.811.277.656.350.350'], ['G09.330.380'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['C06.552.494'], ['A03.620'], ['E... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Benign infantile seizures: a prospective study. | INTRODUCTION: One idiopathic focal epileptic syndrome with onset during infancy is recognized, the benign infantile seizures (BIS).OBJECTIVE: To analyze the electroclinical features and evolution in patients with BIS and assess the difference between familial and non-familial infantile cases.PATIENTS AND METHODS: We pe... | ['Age of Onset', 'Anticonvulsants', 'Diagnosis, Differential', 'Electroencephalography', 'Epilepsies, Myoclonic', 'Epilepsies, Partial', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Neurologic Examination', 'Patient Selection', 'Prospective Studies'] | 19,945,823 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['D27.505.954.427.080'], ['E01.171'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375.130', 'C10.228.140.490.493.063'], ['C10.228.140.490.360'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synmastia: prevention and correction. | Synmastia is a condition of aberrant communication of the breasts. Apart from the rare congenital cases, this is usually a result of technical complications during breast augmentation surgery caused by an overdissection at the medial side of the pocket, over the sternum, in the subglandular plane; or overdivision of th... | ['Adult', 'Breast', 'Cohort Studies', 'Congenital Abnormalities', 'Esthetics', 'Female', 'Follow-Up Studies', 'Humans', 'Iatrogenic Disease', 'Mammaplasty', 'Middle Aged', 'Pectoralis Muscles', 'Reoperation', 'Retrospective Studies', 'Risk Assessment', 'Treatment Outcome', 'Wound Healing', 'Young Adult'] | 20,948,424 | [['M01.060.116'], ['A01.236'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C16.131'], ['F02.463.785.477', 'K01.752.210'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.875'], ... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Joseph's disease: clinical and pathological studies in a Japanese family. | Joseph's disease is a hereditary ataxia found among descendants of Portuguese from the Azores Islands. We describe the clinical and pathological features of 4 members of a Japanese family who were diagnosed as having Joseph's disease. The illness began with cerebellar ataxia between the ages of 18 and 45 years. Nystagm... | ['Adolescent', 'Cerebellar Ataxia', 'Female', 'Genes, Dominant', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Muscle Spasticity', 'Nervous System', 'Pedigree', 'Syndrome'] | 3,963,757 | [['M01.060.057'], ['C10.228.140.252.190', 'C10.597.350.090.500', 'C23.888.592.350.090.200'], ['G05.360.340.024.340.240', 'G05.420.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['C05.651.512', 'C10.597.613.550.550', 'C23.888.592.608.550.550'], ['A08'], [... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Time-scale-invariant information-theoretic contingencies in discrimination learning. | Animals optimize their behavior to maximize rewards by utilizing cues from the environment. In discrimination learning, cues signal when rewards can and cannot be earned by making a particular response. In our experiment, we trained male mice to press a lever to receive a reward on a random interval schedule. We then i... | ['Acoustic Stimulation', 'Animals', 'Behavior, Animal', 'Conditioning, Operant', 'Cues', 'Discrimination Learning', 'Male', 'Mice', 'Reward', 'Time Factors'] | 31,021,132 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['F01.145.113'], ['F02.463.425.179.509'], ['F02.463.425.234'], ['F02.463.425.280'], ['B01.050.150.900.649.313.992.635.505.500'], ['F02.463.425.770.836'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunoglobulin A antibody activity to mutans streptococci in parotid, submandibular and whole saliva. | Antigen extracts of 9 strains of Streptococcus mutans, Streptococcus sobrinus, Streptococcus salivarius and Streptococcus mitis were separated in acrylamide gels by electrophoresis. Strains of the same genotype of mutans streptococci were found to have virtually identical sodium dodecyl sulfate-polyacrylamide gel elect... | ['Adult', 'Antibodies, Bacterial', 'Antigens, Bacterial', 'Bacterial Proteins', 'Blotting, Western', 'Child', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Humans', 'Immunoglobulin A, Secretory', 'Male', 'Parotid Gland', 'Saliva', 'Salivary Glands', 'Salivary Proteins and Peptides', 'Streptococcus', 'Streptococcus ... | 1,299,799 | [['M01.060.116'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D12.776.097'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['M01.060.406'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Heterogeneity of nuclear glucocorticoid receptor interactions. | When thymocytes are incubated with glucocorticoids at 37 degrees, 60--70% of the receptor bound steroid is associated with the nucleus. Under conditions where the rate of steroid-receptor formation is not limiting the transfer of steroid-receptors from the cytoplasm to the nucleus occurs rapidly with a T 1/2 of 30 seco... | ['Animals', 'Cell Nucleus', 'Dexamethasone', 'Hydrocortisone', 'Kinetics', 'Male', 'Osmolar Concentration', 'Rats', 'Receptors, Glucocorticoid', 'Receptors, Steroid', 'Substrate Specificity', 'Thymus Gland', 'Triamcinolone Acetonide'] | 474,292 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
No increase in the prevalence of COPD in two decades. | Relevant information on the prevalence of chronic obstructive pulmonary disease (COPD) and its trends is scarce. In the present study, we compare the prevalence rates and potential determinants of COPD in two national population samples that were surveyed 20 yrs apart. In 1978-1980, a sample of 8,000 people was surveye... | ['Adult', 'Aged', 'Airway Obstruction', 'Female', 'Finland', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Pulmonary Disease, Chronic Obstructive', 'Pulmonary Medicine', 'Respiratory Function Tests', 'Smoking', 'Spirometry', 'Time Factors'] | 20,693,258 | [['M01.060.116'], ['M01.060.116.100'], ['C08.618.846.185'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['C08.381.495.389'], ['H02.403.429.675'], ['E01.370.386... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: a feasibility study. | BACKGROUND: An absence of reliable molecular markers has hampered individualised breast cancer treatments, and a major limitation for translational research is the lack of fresh tissue. There are, however, abundant banks of formalin-fixed paraffin-embedded (FFPE) tissue. This study evaluated two platforms available for... | ['Adult', 'Aged', 'Breast Neoplasms', 'Feasibility Studies', 'Female', 'Formaldehyde', 'Gene Dosage', 'Gene Expression Profiling', 'Humans', 'Middle Aged', 'Paraffin Embedding', 'Tissue Fixation'] | 28,697,743 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['D02.047.407'], ['G05.380.350'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.225.500.620.760.440.610', 'E01.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficient detection of unusual words. | Words that are, by some measure, over- or underrepresented in the context of larger sequences have been variously implicated in biological functions and mechanisms. In most approaches to such anomaly detections, the words (up to a certain length) are enumerated more or less exhaustively and are individually checked in ... | ['Algorithms', 'Base Sequence', 'Biometry', 'DNA, Fungal', 'DNA, Viral', 'Genome, Viral', 'Herpesvirus 1, Human', 'Models, Statistical', 'Pattern Recognition, Automated', 'Saccharomyces cerevisiae', 'Sequence Analysis, DNA'] | 10,890,389 | [['G17.035', 'L01.224.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.225', 'N06.850.505.200'], ['D13.444.308.300'], ['D13.444.308.568'], ['G05.360.340.358.840'], ['B04.280.382.100.750.390'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['L01.399.750'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Class II correction in transitional dentition. | Correcting the developing Class II malocclusion and preventing abnormal relationship of the jaws and occlusal dysfunction by repositioning the permanent molars and incisors is a significant benefit to the growing child. Future orthodontic therapy is significantly reduced often to detailing or eliminated in some cases. | ['Child', 'Dentition, Mixed', 'Humans', 'Malocclusion, Angle Class II', 'Molar', 'Tooth Movement Techniques'] | 11,323,876 | [['M01.060.406'], ['A14.549.167.229'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494.630'], ['A14.549.167.860.525'], ['E06.658.578.836']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases. | INTRODUCTION: Breast cancer cells display preferences for specific metastatic sites including the bone, lung and liver. Metastasis is a complex process that relies, in part, on interactions between disseminated cancer cells and resident/infiltrating stromal cells that constitute the metastatic microenvironment. Distinc... | ['Biomarkers', 'Bone Neoplasms', 'Breast Neoplasms', 'Cell Line, Tumor', 'Chemokines', 'Cluster Analysis', 'Disease Progression', 'Female', 'Gene Expression Profiling', 'Granulocytes', 'Humans', 'Immunohistochemistry', 'Immunophenotyping', 'Liver Neoplasms', 'Lung Neoplasms', 'Lymphocytes, Tumor-Infiltrating', 'Neutrop... | 25,882,816 | [['D23.101'], ['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['C23.550.291.656'], ['E05.393.332... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Family issues in the pathogenesis of anorexia nervosa. | Factors residing in family systems have been implicated in the pathogenesis of anorexia nervosa. In this paper I critically review literature that bears on this issue: the transmission of anorexia nervosa in families; family stress patterns, personality and psychopathological characteristics of parents, parent-child in... | ['Achievement', 'Adolescent', 'Anorexia Nervosa', 'Body Image', 'Communication', 'Diseases in Twins', 'Family', 'Family Characteristics', 'Family Therapy', 'Female', 'Humans', 'Mental Disorders', 'Parent-Child Relations', 'Parents', 'Prognosis', 'Stress, Psychological'] | 7,089,153 | [['F01.658.059', 'F02.784.629.054'], ['M01.060.057'], ['F03.400.125'], ['F01.752.747.792.110', 'F02.463.593.112'], ['F01.145.209', 'L01.143'], ['C23.550.291.750'], ['F01.829.263', 'I01.880.853.150'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['F04.75... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Characterization of a thrombocytopoietic-stimulating factor from kidney cell culture medium. | The chemical characteristics of a thrombocytopoietic-stimulating factor (TSF or thrombopoietin) found in serum-free kidney cell culture medium were further delineated by subjecting the TSF-rich medium to varying temperatures, different pH, and trypsin digested; the ability of TSF to bind lectins on affinity chromatogra... | ['Agglutinins', 'Animals', 'Cells, Cultured', 'Concanavalin A', 'Culture Media', 'Glycoproteins', 'Humans', 'Hydrogen-Ion Concentration', 'Kidney', 'Mice', 'Plant Lectins', 'Temperature', 'Thrombopoietin', 'Triticum', 'Trypsin'] | 7,227,478 | [['D27.505.696.477.136', 'D27.505.954.502.270.232'], ['B01.050'], ['A11.251'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D27.720.470.305', 'E07.206'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Supramolecular and Liquid Crystalline Contributions to the Assembly of Myofibril. | We compare steps observed during the fibrillogenesis of myofibrils with the sequence of steps predictable by a recent analysis of the structurization and functioning of striated muscles. The predicted assembly steps are based solely on fundamental equilibrium processes, particularly supramolecular interactions and liqu... | ['Actin Cytoskeleton', 'Actins', 'Animals', 'Connectin', 'Humans', 'Liquid Crystals', 'Models, Biological', 'Myofibrils', 'Myosins'] | 32,075,335 | [['A11.284.430.214.190.750.050'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D08.811.913.696.620.682.324', 'D12.776.210.500.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.506'], ['E05.599.395'], ['A10.690.552.875', 'A11.284.430.214.190.750.620', 'A11.620.249... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Measurement of Pseudomonas aeruginosa multidrug efflux pumps by quantitative real-time polymerase chain reaction. | Multidrug efflux pumps contribute to multiple antibiotic resistance in Pseudomonas aeruginosa. Pump expression usually has been quantified by Western blotting. Quantitative real-time polymerase chain reaction has been developed to measure mRNA expression for genes of interest. Whether this method correlates with pump p... | ['Bacterial Outer Membrane Proteins', 'Bacterial Proteins', 'Blotting, Western', 'Drug Resistance, Multiple, Bacterial', 'Humans', 'Membrane Transport Proteins', 'Polymerase Chain Reaction', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'RNA, Messenger'] | 15,668,010 | [['D12.776.097.120', 'D12.776.543.100'], ['D12.776.097'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Meal replacements are as effective as structured weight-loss diets for treating obesity in adults with features of metabolic syndrome. | Meal replacements are widely used as a weight-loss strategy; however, their effectiveness outside controlled clinical trial environments is unknown. We compared meal replacements with a structured weight-reduction diet in overweight/obese Australians with raised triglycerides. In a randomized parallel design, 2 groups ... | ['Adult', 'Body Mass Index', 'Carotenoids', 'Diet Fads', 'Diet, Reducing', 'Energy Intake', 'Female', 'Humans', 'Male', 'Micronutrients', 'Middle Aged', 'Obesity', 'Weight Loss'] | 15,284,372 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['G07.203.650.240.250', 'I03.287'], ['E02.642.249.285', 'G07.203.650.240.285'], ['G07.203.650.240.340'], ['B01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Comparison of salivary cytokine levels in oral cancer patients and healthy subjects. | In order to find informative salivary biomarkers specific to oral cancer we examined expression of 4 kinds of cytokine in saliva. Levels of interleukins (IL-1beta, -6, -8) and osteopontin were measured by ELISA using whole saliva samples collected from 19 patients with oral cancer (9 men, 10 women; mean age, 60.9 years... | ['Adult', 'Biomarkers, Tumor', 'Cytokines', 'Female', 'Humans', 'Interleukin-1beta', 'Interleukin-6', 'Interleukin-8', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Osteopontin', 'Saliva', 'Salivary Proteins and Peptides'] | 18,360,107 | [['M01.060.116'], ['D23.101.140'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12.776.467.374.500.400.600', 'D23.529.374.465.131.600', 'D23.529.374.500.400.600'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Over-nutrient environment during both prenatal and postnatal development increases severity of islet injury, hyperglycemia, and metabolic disorders in the offspring. | Prenatal and postnatal over-nutrition has emerged as a new health issue contributing to metabolic disorders in early development of the offspring. Accumulating evidence has suggested that adverse prenatal and postnatal environments gave rise to the predisposition to metabolic syndromes including hyperglycemia, obesity,... | ['Adiposity', 'Animals', 'Blood Glucose', 'Body Weight', 'Diabetes Mellitus', 'Energy Intake', 'Energy Metabolism', 'Female', 'Gluconeogenesis', 'Glycogenolysis', 'Hyperglycemia', 'Insulin', 'Insulin Resistance', 'Insulin Secretion', 'Insulin-Secreting Cells', 'Islets of Langerhans', 'Male', 'Mice, Inbred C57BL', 'Obes... | 26,048,534 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['B01.050'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.452.394.750', 'C19.246'], ['G07.203.650.240.340'], ['G03... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of attitudes and knowledge toward mental disorders in a sample of the Chinese population using a web-based approach. | BACKGROUND: People with mental disorders often encounter stigmatizing attitudes related to their conditions. Stigma often represents one of the critical obstacles that stand in the way of delivering mental health care. The main aim of the study was to assess the knowledge and attitudes toward mental disorders in a samp... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'China', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Internet', 'Male', 'Mental Disorders', 'Middle Aged', 'Rural Population', 'Surveys and Questionnaires', 'Young Adult'] | 30,453,932 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['F03'], [... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Rapid protein depletion from complex samples using a bead-based microfluidic device for the point of care. | Translation of sample preparation methods to point-of-care formats has remained a challenge. We present a plastic laminate microfluidic device for protein depletion from human plasma using ligand immobilized porous beads stored dry within a novel, pneumatically-driven mixer. The card design accelerated the protein depl... | ['Adsorption', 'Analytic Sample Preparation Methods', 'Bacterial Proteins', 'Humans', 'Immobilized Proteins', 'Immunoglobulin G', 'Microfluidic Analytical Techniques', 'Nerve Tissue Proteins', 'Plastics', 'Point-of-Care Systems', 'Time Factors'] | 20,024,034 | [['G01.030', 'G02.020'], ['E05.196.059'], ['D12.776.097'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.463'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E05.588.465'], ['D12.776.631'], ['D05.750.716', 'D25.720.716', 'J01.637.051.720.716'],... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Development of a viral concentration method for bottled water stored in hydrophobic support. | Several protocols have been described for the detection of genomes of enteric viruses from water using two-step procedures: membrane filtration and RT-PCR detection. However, these methods, when applied to bottled water, generally consider only the aqueous phase. Such procedures do not take into account the adhesion of... | ['Animals', 'Cell Adhesion', 'Filtration', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Micropore Filters', 'Mineral Waters', 'Poliovirus', 'Polyethylene Terephthalates', 'RNA, Viral', 'Surface Properties', 'Virology'] | 17,374,404 | [['B01.050'], ['G04.022'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['E05.196.454.403', 'E07.560'], ['D01.045.250.875.600', 'D01.248.497.158.459.650.600', 'D01.650.550.925.600'], ['B04.820.578.750.284.184.500'], ['D05.750.728.764', 'D25.720.728.764', 'J01.637.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Evaluation on the method to test the sex-improve function and its key points]. | The mating-test with normal mouse is one of the methods built to test wheather the type of sexual function improvement food could improve the sexual function. Through controlling the influence factor of the experiment such as the most suitabke mating time, the weights of mating mice, the mating temperature and the mati... | ['Animals', 'Drugs, Chinese Herbal', 'Estrus', 'Female', 'Gonadotropins, Equine', 'Male', 'Mice', 'Sexual Behavior, Animal'] | 10,325,619 | [['B01.050'], ['D20.215.784.500.350', 'D26.335'], ['G08.686.195.500'], ['D06.472.699.322.451', 'D06.472.699.649.451', 'D12.644.548.726.451', 'D12.776.780.451'], ['B01.050.150.900.649.313.992.635.505.500'], ['F01.145.113.252.748']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Transjugular intrahepatic portosystemic shunt (TIPS)]. | Transjugular intrahepatic portosystemic (TIPS) is radiological technique that has opened up new therapeutic horizons in the treatment of portal hypertension. Technically, the procedure includes catheterizing of the suprahepatic veins, prevalently right or middle, by means of transjugular access, and the creation of an ... | ['Adult', 'Aged', 'Esophageal and Gastric Varices', 'Female', 'Follow-Up Studies', 'Gastrointestinal Hemorrhage', 'Humans', 'Hypertension, Portal', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Portasystemic Shunt, Surgical', 'Postoperative Complications', 'Radiography', 'Stents'] | 7,700,557 | [['M01.060.116'], ['M01.060.116.100'], ['C06.405.117.240', 'C06.552.494.414'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.11... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Therapeutic effect and risk factors for complications of excision in 76 patients with schwannoma. | BACKGROUND: Benign schwannoma is the most common tumor of peripheral nerves. However, the clinical course of excision and risk factors associated with postoperative neurological deficits are not well known. We evaluated the incidence of preoperative symptoms, the incidence of postoperative neurological deficits, and th... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Japan', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neurilemmoma', 'Neurosurgical Procedures', 'Peripheral Nervous System Neoplasms', 'Postoperative Complications', 'Prognosis', 'Retrospective Studies', 'Risk Factors... | 24,105,254 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mosquito infectivity is directly related to the proportion of repetitive DNA in Plasmodium berghei. | A strain of Plasmodium berghei (NK 65) was followed during syringe transmission in mice for over 120 passages after the last complete cycle, while the following parameters were monitored: (a) capacity to infect mosquitoes, inducing oocyst formation; (b) presence in the peripheral blood of morphologically identifiable g... | ['Aedes', 'Animals', 'DNA', 'Kinetics', 'Malaria', 'Mice', 'Mice, Inbred ICR', 'Nucleic Acid Renaturation', 'Plasmodium berghei', 'Rats', 'Rats, Inbred Strains', 'Repetitive Sequences, Nucleic Acid'] | 7,050,700 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['D13.444.308'], ['G01.374.661', 'G02.111.490'], ['C01.610.752.530', 'C01.920.875'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['G02.111.619'], ['B01.043.075.380.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infant room-sharing and prone sleep position in sudden infant death syndrome. New Zealand Cot Death Study Group. | BACKGROUND: There is evidence that the risk of sudden infant death syndrome is lower among ethnic groups in which parents generally share a room with the infant for sleeping. We investigated whether the presence of other family members in the infant's sleeping room affects the risk of the sudden infant death syndrome.M... | ['Adult', 'Beds', 'Case-Control Studies', 'Child', 'Child Rearing', 'Europe', 'Humans', 'Infant', 'Infant, Newborn', 'Interviews as Topic', 'Maternal Behavior', 'New Zealand', 'Odds Ratio', 'Parents', 'Polynesia', 'Prone Position', 'Risk', 'Risk Factors', 'Sleep', 'Smoking', 'Sudden Infant Death'] | 8,531,589 | [['M01.060.116'], ['E07.325.220'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['F01.318'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Gene transfection efficiency of tracheal epithelial cells by DC-chol-DOPE/DNA complexes. | We evaluated the transfection efficiency of five different cationic liposome/plasmid DNA complexes, during the in vitro gene transfer into human epithelial tracheal cell lines. A dramatic correlation between the transfection efficiency and the charge ratio (positive charge of liposome to negative charge of DNA) has bee... | ['Cell Line, Transformed', 'Cholesterol', 'DNA', 'Epithelial Cells', 'Fluorescent Dyes', 'Genetic Therapy', 'Humans', 'Liposomes', 'Microscopy, Confocal', 'Microscopy, Electron', 'Organic Chemicals', 'Phosphatidylethanolamines', 'Trachea', 'Transfection'] | 10,407,070 | [['A11.251.210.172'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D13.444.308'], ['A11.436'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E02.095.301', 'E05.393.420.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Variable-interval responding in the horse: a sensitive method of quantitating effects of centrally acting drugs. | An operant conditioning apparatus for studies in equine pharmacology was constructed. Horses interacted with this apparatus by breaking a light beam and were rewarded with 30 ml of oats. Horses readily learned to use this apparatus and were trained to respond on a variable-interval-60 schedule. With this schedule, ther... | ['Animals', 'Cocaine', 'Conditioning, Operant', 'Dose-Response Relationship, Drug', 'Female', 'Horses', 'Male', 'Methods', 'Reaction Time', 'Reserpine', 'Time Factors'] | 7,103,192 | [['B01.050'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['F02.463.425.179.509'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.984.235.472'], ['E05.581'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['D03.132.436.681.933.500', 'D03.63... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Early spinal bone loss in Klinefelter syndrome. X-ray computed tomographic evaluation in 16 cases]. | The lumbar spine bone density (BMD) was assessed by single energy quantitative tomography in 16 young patients with non traited Klinefelter's syndrome (19 +/- 2.2 yr) and in 16 age weight- and height-matched control males. The BMD were significantly lower in the patients than in the control group (175 +/- 26 mg/cm3 K2H... | ['Absorptiometry, Photon', 'Adolescent', 'Adult', 'Bone Density', 'Bone Resorption', 'Case-Control Studies', 'Estradiol', 'Humans', 'Klinefelter Syndrome', 'Lumbar Vertebrae', 'Male', 'Osteoporosis', 'Testosterone'] | 8,167,626 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.057'], ['M01.060.116'], ['G11.427.100'], ['C05.116.264', 'G11.427.213.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro organo-protective effect of bark extracts from Syzygium guineense var macrocarpum against ferric-nitrilotriacetate-induced stress in wistar rats homogenates. | BACKGROUND: Overconsumption of oxygen in mammalian cells often lead to the production of reactive oxygen species (ROS) resulting from different mechanisms. Escape of scavenging enzymes/components or nutritional failure are the most important origins. Plant-derived molecules may protect biological molecules either by qu... | ['Animals', 'Ferric Compounds', 'Glutathione', 'Lipid Peroxidation', 'Nitrilotriacetic Acid', 'Oxidative Stress', 'Plant Bark', 'Plant Extracts', 'Protective Agents', 'Rats', 'Rats, Wistar', 'Superoxide Dismutase', 'Syzygium'] | 27,561,333 | [['B01.050'], ['D01.490.100'], ['D12.644.456.448'], ['G02.111.515', 'G03.295.531.587'], ['D02.241.081.018.588'], ['G03.673', 'G07.775.750'], ['A18.024.750.200'], ['D20.215.784.500', 'D26.667'], ['D27.505.696.706', 'D27.720.799'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcatheter treatment of tricuspid regurgitation using edge-to-edge repair: procedural results, clinical implications and predictors of success. | AIMS: The aim of this study was to analyse the feasibility, safety and effectiveness of tricuspid valve (TV) repair using the MitraClip system in patients at high surgical risk.METHODS AND RESULTS: Forty-two elderly high-risk patients (76.8±7.3 years, EuroSCORE II 8.1±5.7) with isolated TR or combined TR and mitral reg... | ['Aged', 'Aged, 80 and over', 'Heart Valve Prosthesis Implantation', 'Humans', 'Mitral Valve', 'Treatment Outcome', 'Tricuspid Valve Insufficiency'] | 29,633,941 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.510.507'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C14.280.484.856']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of myosin heavy-chain isoforms in the respiratory muscles following inspiratory resistive breathing. | We investigated the effect of inspiratory resistive breathing (IRB) on the expression of the genes encoding fast and slow isoforms of myosin heavy chain (MyHC) in respiratory muscles. Eleven mongrel dogs were studied for baseline MyHC messenger RNA (mRNA) expression, seven of which were also used to study the effects o... | ['Animals', 'Dogs', 'Intubation, Intratracheal', 'Muscle, Skeletal', 'Myosin Heavy Chains', 'RNA, Messenger', 'Respiration', 'Respiratory Mechanics', 'Respiratory Muscles'] | 10,764,323 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['A02.633.567', 'A10.690.552.500'], ['D05.750.078.730.475.100', 'D08.811.277.040.025.193.750.249', 'D12.776.210.500.600.100', 'D12.776.220.525.475.100'], ['D13.444.735.544'], ['G09.772.705'], ['G09.772.705.700'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of vitamin D in children with hepatosteatosis. | BACKGROUND: The increasing incidence of obesity in children is a significant risk factor for nonalcoholic fatty liver disease and obesity-associated morbidity. Vitamin D has a major role in bone mineral metabolism and has antimicrobial, antioxidant properties. In this study we aimed to investigate the role of vitamin D... | ['Adolescent', 'Alkaline Phosphatase', 'Arabidopsis Proteins', 'Body Mass Index', 'Calcium', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Insulin Resistance', 'Male', 'Non-alcoholic Fatty Liver Disease', 'Obesity', 'Parathyroid Hormone', 'Severity of Illness Index', 'Sex Factors', 'Ultrason... | 24,647,335 | [['M01.060.057'], ['D08.811.277.352.650.035'], ['D12.776.765.149'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of variable lighting intensities and colour temperatures on sulphatoxymelatonin and subjective mood in an experimental office workplace. | Workplace illumination is of paramount importance in determining the employee's productivity and well-being. Moreover, light exerts non-visual effects with respect to biological rhythms. In this study, we investigated the impact of different lighting conditions (500-1800 lx, 6500 K; 500 lx, 4000 K) on sulphatoxymelaton... | ['Adult', 'Affect', 'Circadian Rhythm', 'Color', 'Cross-Over Studies', 'Humans', 'Light', 'Lighting', 'Male', 'Melatonin', 'Neopterin', 'Statistics, Nonparametric', 'Surveys and Questionnaires', 'Temperature', 'Visual Perception', 'Workplace'] | 18,164,275 | [['M01.060.116'], ['F01.470.047'], ['G07.180.562.190'], ['G01.590.540.199'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['N06.230.150.410'], ['D03.633.100.473.914.481', ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Achieving visibility? Use of non-verbal communication in interactions between patients and pharmacists who do not share a common language. | Despite the seemingly insatiable interest in healthcare professional-patient communication, less attention has been paid to the use of non-verbal communication in medical consultations. This article considers pharmacists' and patients' use of non-verbal communication to interact directly in consultations in which they ... | ['Adult', 'Aged', 'Analgesics', 'Anti-Asthmatic Agents', 'Asthma', 'Female', 'Humans', 'Iron Compounds', 'Language', 'London', 'Male', 'Middle Aged', 'Nebulizers and Vaporizers', 'Nonverbal Communication', 'Pain', 'Pharmacists', 'Professional-Patient Relations'] | 24,641,161 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['D27.505.954.796.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.490'], ['F01.145.209.399', 'L01.559'], ['Z01.433.553', 'Z01.542.363.300.553... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Human liver cDNA clones encoding proteolipid subunit 9 of the mitochondrial ATPase complex. | Clones encoding the proteolipid subunit 9 of the mitochondrial ATPase complex have been isolated from a lambda gt10 library of human liver cDNA sequences, using a probe of Neurospora crassa cDNA encoding subunit 9. From nucleotide sequence analysis it is concluded that the amino acid sequence of mature human subunit 9 ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cattle', 'Cloning, Molecular', 'DNA', 'Genes', 'Humans', 'Macromolecular Substances', 'Mitochondria, Liver', 'Proteolipids', 'Proton-Translocating ATPases', 'Sequence Homology, Nucleic Acid'] | 2,883,974 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.500.380.271'], ['E05.393.220'], ['D13.444.308'], ['G05.360.340.024.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05'], ['A11.284.430.214.190.875.564.461', 'A11.284.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Multilamellar hydrodissection in phacoemulsification and planned extracapsular surgery. | Multilamellar hydrodissection is the injection of balanced salt solution into multiple lamellae of the lens, cleaving it into a small nucleus and multiple layers of cortex. In phacoemulsification, the smaller nucleus reduces phacoemulsification time, and the thicker bed of cortex provides greater protection for the pos... | ['Cataract Extraction', 'Humans', 'Injections', 'Lens, Crystalline', 'Lenses, Intraocular', 'Prognosis', 'Solutions'] | 2,231,369 | [['E04.540.825.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['A09.371.060.500'], ['E07.632.500.460', 'E07.695.460'], ['E01.789'], ['D26.776']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Global protected area expansion is compromised by projected land-use and parochialism. | Protected areas are one of the main tools for halting the continuing global biodiversity crisis caused by habitat loss, fragmentation and other anthropogenic pressures. According to the Aichi Biodiversity Target 11 adopted by the Convention on Biological Diversity, the protected area network should be expanded to at le... | ['Animals', 'Biodiversity', 'Conservation of Natural Resources', 'Ecosystem', 'International Cooperation'] | 25,494,203 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['I01.615.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Caution in the use of boldo in herbal laxatives: a case of hepatotoxicity. | A case is reported in which a several-fold increase in transaminases and gamma-GT was detected in an elderly male patient with fatty liver. The patient was regularly taking a mixture of herbal products, used as a laxative, for a number of years, with no alteration of blood chemistry until 6 months before the present ob... | ['Aged', 'Aged, 80 and over', 'Cathartics', 'Chemical and Drug Induced Liver Injury', 'Constipation', 'Humans', 'Male', 'Peumus', 'Phytotherapy', 'Plant Extracts', 'Plant Leaves'] | 15,764,158 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.483.396'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['C23.888.821.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.650.940.800.575.912.250.595.600.500'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['A18.024.812']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of endurance training on beta-adrenergic system in three different skeletal muscles. | The beta-adrenergic receptor density (Bmax) and adenylate cyclase (AC) activity in the soleus muscle and deep red and white superficial portions of the vastus lateralis muscle were evaluated in a group of rats submitted to a progressive 10-wk treadmill running program (n = 19) and compared with a group of rats kept sed... | ['Adenylyl Cyclases', 'Animals', 'Isoproterenol', 'Male', 'Muscles', 'Physical Conditioning, Animal', 'Physical Endurance', 'Rats', 'Rats, Wistar', 'Receptors, Adrenergic, beta', 'Sodium Fluoride'] | 8,390,439 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.389.657.166.175.649'], ['A02.633', 'A10.690'], ['G11.427.410.698.277.280'], ['G11.427.680', 'I03.450.642.845.054.600'], ['B01.050.150.900.649.313.992.635.505.70... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
Isolation and structural characterization of Coryxin, a novel cyclic lipopeptide from Corynebacterium xerosis NS5 having emulsifying and anti-biofilm activity. | Herein we reported the structure and several properties of a new biosurfactants produced by Corynebacterium xerosis strain NS5. This strain was capable of producing a novel lipopeptide biosurfactant that we have named coryxin. The biosurfactant structure was characterized by using Fourier transform infrared spectroscop... | ['Anti-Bacterial Agents', 'Bacterial Adhesion', 'Biofilms', 'Corynebacterium', 'Emulsifying Agents', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Lipopeptides', 'Micelles', 'Microbial Sensitivity Tests', 'Peptides, Cyclic', 'Surface Tension', 'Surface-Active Agents'] | 26,280,817 | [['D27.505.954.122.085'], ['G06.099.050'], ['A20.593', 'G06.120'], ['B03.510.024.250', 'B03.510.460.400.400.200'], ['D27.720.877.383'], ['B03.440'], ['B03.510'], ['D10.477', 'D12.644.365'], ['D05.374', 'D26.255.560'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D04.345.566', 'D12.644.641'], ['G02.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lung nodules are reliably detectable on ultra-low-dose CT utilising model-based iterative reconstruction with radiation equivalent to plain radiography. | AIM: To determine if ultra-low-dose (ULD) computed tomography (CT) utilising model-based iterative reconstruction (MBIR) with radiation equivalent to plain radiography allows the detection of lung nodules.MATERIALS AND METHODS: Ninety-nine individuals undergoing surveillance of solid pulmonary nodules undertook a low-d... | ['Aged', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Multiple Pulmonary Nodules', 'Obesity', 'Radiation Dosage', 'Risk Factors', 'Smoking', 'Solitary Pulmonary Nodule', 'Tomography, X-Ray Computed'] | 30,832,990 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['C04.588.894.797.520.237', 'C08.381.540.148', 'C08.785.520.148'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.10... | ['Named Groups [M]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Being in another world: transcultural student experiences using service learning with families who are homeless. | Developing skills in cultural competence is a recognized theoretical strategy in schools of nursing. Nursing faculty know that students need to be sensitized to the concept of diversity; however, many are struggling with the best way to teach cultural competence. This article describes transcultural experiences from se... | ['Adaptation, Psychological', 'Attitude of Health Personnel', 'Clinical Competence', 'Cultural Diversity', 'Education, Nursing, Baccalaureate', 'Empathy', 'European Continental Ancestry Group', 'Family', 'Health Knowledge, Attitudes, Practice', 'Health Services Needs and Demand', 'Homeless Persons', 'Humans', 'Models, ... | 17,416,719 | [['F01.058'], ['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['I02.358.462.316'], ['F01.752.355', 'F01.752.543.500.500'], ['M01.686.508.400'], ['F01.829.263', 'I01.880.853.150'], ['F01.100.150.500', 'N05.300.150.410'], ['N03.349.380.420... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Antimicrobial activity of a new derivative: N-(4-chlorobenzyl)-2-(1H-imidazol-1-ylmethyl)benzenamine. | The activity of a new antifungal agent, an imidazolylmethylaniline derivative (XX H), synthesized by the authors, has been studied in vitro and in vivo. Antimicrobial data, in comparison with miconazole, ketoconazole and bifonazole, show antimicotic activity. The results are discussed on the basis of structure-activity... | ['Aniline Compounds', 'Animals', 'Antifungal Agents', 'Candida', 'Candida albicans', 'Gram-Negative Bacteria', 'Imidazoles', 'Ketoconazole', 'Male', 'Miconazole', 'Microbial Sensitivity Tests', 'Rabbits'] | 2,076,654 | [['D02.092.146'], ['B01.050'], ['D27.505.954.122.136'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['B03.440'], ['D03.383.129.308'], ['D03.383.606.560'], ['D03.383.129.308.550'], ['E01.370.225.875.595', 'E05.200.875.595', 'E0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis, cytotoxicity and DNA binding of oxoazabenzo[de]anthracenes derivatives in colon cancer Caco-2 cells. | New oxoazabenzo[de]anthracenes derivatives were synthesised and characterised. Their interactions with calf thymus DNA were studied by UV spectrophotometric analysis and a competitive ethidium bromide displacement assay. Cytotoxicity was determined by MTT assay, against colon adenocarcinoma (Caco-2 cells). Among all th... | ['Animals', 'Antineoplastic Agents', 'Benzoxazines', 'Binding Sites', 'Caco-2 Cells', 'Cattle', 'Cell Proliferation', 'DNA', 'Dose-Response Relationship, Drug', 'Drug Screening Assays, Antitumor', 'Heterocyclic Compounds, 4 or More Rings', 'Humans', 'Molecular Structure', 'Structure-Activity Relationship', 'Tumor Cells... | 24,099,994 | [['B01.050'], ['D27.505.954.248'], ['D03.383.533.249', 'D03.633.100.209'], ['G02.111.570.120'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['B01.050.150.900.649.313.500.380.271'], ['G04.161.750', 'G07.345.249.410.750'], ['D13.444.308'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.388',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distal bowel surgical margin shorter than 1 cm after preoperative radiation for rectal cancer: is it safe? | BACKGROUND: The primary end-point of our randomized trial was sphincter preservation. The secondary aim was to evaluate whether distal bowel clearance < or =1 cm is safe after radiation.METHODS: The study randomized 312 patients with cT3-4 resectable low-lying and mid-rectal cancer to receive either preoperative irradi... | ['Adult', 'Aged', 'Anal Canal', 'Antineoplastic Combined Chemotherapy Protocols', 'Female', 'Fluorouracil', 'Humans', 'Intestines', 'Leucovorin', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Preoperative Care', 'Prognosis', 'Prospective Studies', 'Rectal Neoplasms', 'Survival Rate', 'Treatm... | 18,766,404 | [['M01.060.116'], ['M01.060.116.100'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['D03.633.100.733.631.400.800.350.450', 'D08.211.840.300.500'], ['M01.060.116.6... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Comparative examination of selected blood parameters from different sampling sites in high yielding cows. Practical usability of blood sampling from the udder vein for metabolic analyses]. | OBJECTIVE: The aim of the present study was to evaluate different statements in the literature on the influence of the sampling site on various blood parameters in a larger amount of animals. In addition, the practical usability of blood sampling from the udder vein or other accessible veins (e. g. saphenous vein or ta... | ['Animals', 'Biomarkers', 'Blood Chemical Analysis', 'Cattle', 'Dairying', 'Female', 'Mammary Glands, Animal', 'Phlebotomy', 'Veins'] | 23,403,755 | [['B01.050'], ['D23.101'], ['E01.370.225.124.100', 'E05.200.124.100'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['A10.336.482', 'A13.589'], ['E01.370.225.998.110.625', 'E02.800.558', 'E04.665.150.625', 'E05.200.998.110.625'], ['A07.015.908']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Project Prescription for Hope (RxH): trauma surgeons and community aligned to reduce injury recidivism caused by violence. | The recidivism rate for violent injuries in the United States has been reported as high as 45 per cent. Based on a retrospective review, the 5-year recidivism rate at the Indiana University/Wishard Trauma Center is 31 per cent, and the 1-year recidivism rate is 8.7 per cent. Individuals who have been admitted with a v... | ['Adolescent', 'Adult', 'Community Health Services', 'Female', 'Health Promotion', 'Humans', 'Indiana', 'Interinstitutional Relations', 'Juvenile Delinquency', 'Male', 'Middle Aged', 'Organizational Objectives', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Trauma Centers', 'Traumatology', 'Violence', 'Wounds... | 22,964,211 | [['M01.060.057'], ['M01.060.116'], ['N02.421.143'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.360', 'Z01.107.567.875.510.360'], ['N04.452.822.400'], ['I01.880.735.479'], ['M01.060.116.630'], ['N04.452.615'], ['C23.550.291.937'], ['E05.318.372.500.... | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
DNA sequence analysis of an immediate-early gene region of the herpes simplex virus type 1 genome (map coordinates 0.950 to 0.978). | The nucleotide sequence of 4 kilobases of DNA from within the short region of the genome of herpes simplex virus type 1 has been determined. This portion of DNA contains the junctions of the terminal and inverted repeat sequence components with the unique sequence component and the 5'-regions of the genes which encode ... | ['Amino Acid Sequence', 'Base Composition', 'Base Sequence', 'DNA Restriction Enzymes', 'DNA, Viral', 'Deoxyribonuclease BamHI', 'Genes, Viral', 'RNA, Messenger', 'RNA, Viral', 'Repetitive Sequences, Nucleic Acid', 'Simplexvirus', 'Transcription, Genetic', 'Viral Proteins'] | 6,290,591 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.568'], ['D08.811.150.280.260.240', 'D08.811.277.352.335.350.300.260.240', 'D08.811.277.352.355.325.300... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Heritability of biochemical kidney markers and relation to survival in the elderly--results from a Danish population-based twin study. | BACKGROUND AND AIM: We performed a twin study to assess the relative contribution of genetic and environmental factors to serum levels of urea, creatinine, urate and sodium in a population of 688 elderly twins (73-95 years). Furthermore, we tested the association between these biochemical values and mortality to examin... | ['Aged', 'Aged, 80 and over', 'Alcohol Drinking', 'Algorithms', 'Biomarkers', 'Blood Urea Nitrogen', 'Body Mass Index', 'Creatinine', 'Denmark', 'Environment', 'Female', 'Humans', 'Kidney', 'Longitudinal Studies', 'Male', 'Sodium', 'Survival', 'Survival Analysis', 'Twins', 'Uric Acid'] | 15,469,867 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.145.317.269'], ['G17.035', 'L01.224.050'], ['D23.101'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D03.383.129.308.207'], ['Z01.542.816.124... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, ... | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
An automatic pulsed laser microfluorometer with high spatial and temporal resolution. | The paper describes an automatic pulsed laser microfluorometer with high spatial and temporal resolution, developed in our laboratories. The instrument consists of: (i) a nitrogen-laser-pumped dye-laser for the excitation of the fluorescence, (ii) a microscope with additional optics to focus the excitation beam on the ... | ['Animals', 'Base Composition', 'Chromatin', 'DNA', 'Humans', 'Lasers', 'Lymphocytes', 'Microscopy, Fluorescence', 'Plant Cells'] | 6,737,469 | [['B01.050'], ['G02.111.080'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490', 'E07.710.520'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['E01.370.350.515.458', 'E05.595.458'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Home Care for Cancer Patients During COVID-19 Pandemic: The Double Triage Protocol. | Patients with cancer have an increased risk of developing severe forms of coronavirus disease 2019, and patients with advanced cancer who are followed at home represent a particularly frail population. Although with substantial differences, the challenges that cancer care professionals have to face during a pandemic ar... | ['COVID-19', 'Coronavirus Infections', 'Home Care Services', 'Humans', 'Italy', 'Neoplasms', 'Palliative Care', 'Pandemics', 'Pneumonia, Viral', 'Psychology, Clinical', 'Telemedicine', 'Telephone', 'Triage'] | 32,240,755 | [['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['C04'], ['E02.760.666', 'N02.421... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Infants show early comprehension of basic color words. | Previous research has highlighted the difficulty that infants have in learning to use color words. Even after acquiring the words themselves, infants are reported to use them incorrectly, or overextend their usage. We tested 146 infants from 5 different age groups on their knowledge of 6 basic color words, red, green, ... | ['Acoustic Stimulation', 'Age Factors', 'Child Development', 'Child, Preschool', 'Color Perception', 'Comprehension', 'Female', 'Humans', 'Infant', 'Male', 'Photic Stimulation', 'Regression Analysis', 'Verbal Learning'] | 30,489,137 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['F02.463.593.932.217'], ['F02.463.188.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.723.729'], ['E05.318.740.750', 'N05.715.360.750.695', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Outline of the revision of ISO 15189 and accreditation of medical laboratory for specified health checkup]. | GOAL which accredited medical laboratory aims at is to continue "offering useful laboratory's service for patient medicine and treatment or the health of the nation". The medical laboratory, administers a quality management system, is competent technically and offers laboratory's service to satisfy the needs of all pat... | ['Accreditation', 'Clinical Laboratory Techniques', 'Humans', 'Laboratories', 'Physical Examination', 'Quality Assurance, Health Care', 'Quality of Health Care', 'Total Quality Management'] | 18,154,036 | [['N03.706.110.070', 'N05.700.200.100'], ['E01.370.225', 'E05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J03.520', 'N02.278.487'], ['E01.370.600'], ['N04.761.700', 'N05.700'], ['N04.761', 'N05.715'], ['N04.452.955', 'N04.761.700.675', 'N05.700.792']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Nonnegligible increasing temporal trends in unprotected anal intercourse among men who have sexual relations with other men in Montreal. | OBJECTIVE: The objective of this study is to determine temporal trends in unprotected anal intercourse (UAI) among men who have sex with other men (MSM) participating in the Omega Cohort Study, 1997-2003.METHODS: The Omega Cohort Study was a longitudinal study of HIV-negative MSM aged 16 years or older and living in Mo... | ['Adolescent', 'Adult', 'Aged', 'Homosexuality, Male', 'Humans', 'Interviews as Topic', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Quebec', 'Sexual Behavior', 'Surveys and Questionnaires', 'Unsafe Sex'] | 16,540,939 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Audiological evaluation of nonalcoholic, drug-free posttraumatic stress disorder patients. | Auditory functions of 32 Israeli soldiers with posttraumatic stress disorder (PTSD) were evaluated and compared with those of 32 matched controls without PTSD. The evaluation included peripheral auditory functions, tolerance to noise, and central auditory informational functions. Tolerance of intense auditory stimuli b... | ['Adult', 'Arousal', 'Attention', 'Auditory Perception', 'Auditory Threshold', 'Combat Disorders', 'Dominance, Cerebral', 'Hearing Loss, Noise-Induced', 'Humans', 'Loudness Perception', 'Male', 'Psychophysiologic Disorders', 'Speech Perception', 'Stress Disorders, Post-Traumatic'] | 3,167,141 | [['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['F02.830.104.214'], ['F02.463.593.071', 'G07.888.125'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['F03.950.750.249'], ['F02.830.297', 'G11.561.225'], ['C09.218.458.341.887.460', 'C10.597.751.418.341.887.460', 'C23.888.592.763.393.341.887.460']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Left ventricular flow propagation velocity measurement: Is it cast in stone? | This study aims to investigate the measurement of left ventricular flow propagation velocity, V p, using phase contrast magnetic resonance imaging and to assess the discrepancies resulting from inflow jet direction and individual left ventricular size. Three V p measuring techniques, namely non-adaptive (NA), adaptive ... | ['Blood Flow Velocity', 'Diastole', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Myocardial Contraction', 'Ventricular Function, Left'] | 28,321,684 | [['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.510.507'], ['G09.330.580', 'G11.427.494.570'], ['G09.330.955.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Embryonic versus adult myocardium: adenine nucleotide degradation during ischemia. | Neonatal myocardium demonstrates better recovery from ischemia than does adult tissue. We tested the hypothesis that developmental differences in adenine nucleotide degradation might facilitate recovery by quantitating depletion of high-energy phosphates in nine-day-old embryonic (n = 9) and 15-month-old adult (n = 14)... | ['Adenine Nucleotides', 'Animals', 'Chick Embryo', 'Chickens', 'Chromatography, High Pressure Liquid', 'Coronary Disease', 'Heart', 'Myocardium', 'Nucleosides', 'Time Factors'] | 2,764,588 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['B01.050'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.300'], ['C14.280.647.250', 'C14.907.585.250'], ['A07.541'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D09.408.595'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Obstetric Outcomes and Delivery-Related Health Care Utilization and Costs Among Pregnant Women With Multiple Chronic Conditions. | Our objective was to measure obstetric outcomes and delivery-related health care utilization and costs among pregnant women with multiple chronic conditions. We used 2013-2014 data from the National Inpatient Sample to measure obstetric outcomes and delivery-related health care utilization and costs among women with no... | ['Case-Control Studies', 'Cesarean Section', 'Chronic Disease', 'Cross-Sectional Studies', 'Female', 'Humans', 'Length of Stay', 'Logistic Models', 'Maternal Mortality', 'Multiple Chronic Conditions', 'Population Surveillance', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Premature Birth', 'Retrospecti... | 29,420,168 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.520.252.500'], ['C23.550.291.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E05.318.740.500.525', 'E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A biological phantom for contrast-media-based perfusion studies with CT. | OBJECTIVES: Perfusion computed tomography (PCT) is increasingly getting popular with the advent of computed tomography (CT) systems with adequate temporal resolution and spatial coverage. We sought to develop a biological phantom for perfusion measurements in CT to design, improve, and validate scan protocols and postp... | ['Animals', 'Contrast Media', 'Equipment Design', 'Equipment Failure Analysis', 'Kidney', 'Perfusion Imaging', 'Phantoms, Imaging', 'Swine', 'Tomography, X-Ray Computed'] | 19,724,231 | [['B01.050'], ['D27.505.259.500', 'D27.720.259'], ['E05.320'], ['E05.325.192'], ['A05.810.453'], ['E01.370.350.710.600', 'E01.370.384.730.354'], ['E07.671'], ['B01.050.150.900.649.313.500.880'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal. | A key challenge in the SAD phasing method is solving a structure when the anomalous signal-to-noise ratio is low. Here, algorithms and tools for evaluating and optimizing the useful anomalous correlation and the anomalous signal in a SAD experiment are described. A simple theoretical framework [Terwilliger et al. (2016... | ['Algorithms', 'Crystallography, X-Ray', 'Probability', 'Protein Conformation', 'Proteins', 'Signal-To-Noise Ratio'] | 26,960,123 | [['G17.035', 'L01.224.050'], ['E05.196.309.742.225'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['G02.111.570.820.709'], ['D12.776'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.85... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Use of an osteometer in the planning of a mandibular prosthesis]. | For series determining of small dimensions at high accuracy a pistollike measuring instrument has been devised which is well suitable for planning mandible prostheses, for instance for obtaining the with dimensions of the mandibula corpus basalis or for example for determining the mesio distal diameter of the teeth. | ['Anthropometry', 'Humans', 'Mandible', 'Mandibular Prosthesis', 'Prosthesis Design'] | 2,612,634 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['E07.695.510.500'], ['E05.320.550', 'E07.695.680']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of intermittent nasogastric feeding on preventing aspiration pneumonia in ventilated critically ill patients. | This randomized, controlled study employed two feeding protocols for 107 participants in two intensive care units (ICUs) of a medical center to investigate the efficacy of intermittent nasogastric (NG) feeding in preventing aspiration pneumonia in critically ill patients on ventilators. The participants were randomly a... | ['Critical Illness', 'Enteral Nutrition', 'Humans', 'Intensive Care Units', 'Intubation, Gastrointestinal', 'Outcome Assessment, Health Care', 'Pneumonia, Aspiration', 'Respiration, Artificial'] | 16,967,399 | [['C23.550.291.625'], ['E02.421.360', 'E02.642.500.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E02.585.412', 'E05.497.412'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['C01.748.610.529', 'C08.381.677.529', 'C08.730.610.529'], ['E02.041.625', 'E02.365.647.729',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Interpretation of serum ferritin concentrations as indicators of total-body iron stores in survey populations: the role of biomarkers for the acute phase response. | BACKGROUND: Nutritional surveys use acute phase protein (APP) biomarkers such as C-reactive protein (CRP) and alpha1-acid glycoprotein (AGP) to identify the influence of inflammation on the distribution of iron status biomarkers. Few, however, have examined which biomarker better identifies persons with spurious elevat... | ['Acute-Phase Proteins', 'Acute-Phase Reaction', 'Anemia, Iron-Deficiency', 'Biomarkers', 'C-Reactive Protein', 'Child', 'Cross-Sectional Studies', 'Female', 'Ferritins', 'Guatemala', 'Humans', 'Infant', 'Inflammation', 'Iron', 'Iron, Dietary', 'Male', 'Michigan', 'Nutritional Status', 'Orosomucoid', 'Pilot Projects', ... | 17,158,435 | [['D12.776.124.050'], ['C23.550.470.099'], ['C15.378.071.196.300', 'C18.452.565.100'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['Z01.107... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. | Phytochemical investigation of the stem bark of Myristica fatua Houtt. led to the isolation of a new compound 1 (3-tridecanoylbenzoic acid), along with six known acylphenols (2-7). All the compounds displayed moderate inhibitory activity on á-amylase and significant activity on á-glucosidase; however malabaricone B (6)... | ['Binding Sites', 'Cell Line', 'Cell Survival', 'Diabetes Mellitus, Type 2', 'Glycoside Hydrolase Inhibitors', 'Humans', 'Hypoglycemic Agents', 'Molecular Dynamics Simulation', 'Muscle Cells', 'Myristicaceae', 'Phytochemicals', 'Plant Bark', 'Plant Extracts', 'Plant Stems', 'Protein Structure, Tertiary', 'Resorcinols',... | 29,789,207 | [['G02.111.570.120'], ['A11.251.210'], ['G04.346'], ['C18.452.394.750.149', 'C19.246.300'], ['D27.505.519.389.320', 'D27.505.696.422.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['A11.620'], ['B01.650.940.800.575.912.250.765'], [... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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