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498c9184-26ab-4019-80ee-b1f476b634bf | True about Gaucher disease | Due to deficiency of enzymes sphingomyelinase | Due to deficiency of enzyme b-Gluco-cerebroisidase | Deposition of glucosylceramide | Foam cell deposition | 1b | multi | This is an inborn error of metabolism due to failure of degradation of glucocerebrosides. The enzyme beta-glucosidase is deficient in this condition.Ref: DM Vasudevan, 7th edition, page no: 192 | Biochemistry | Metabolism of carbohydrate |
813b6cdb-7925-44ba-8e39-b3bcb2a8b0c6 | Stages of pneumonia are all except:- | Stage of Exudation | Stage of Red hepatisation | Stage of Cavitation | Stage of Resolution | 2c | multi | The stages of pneumonia/consolidation are:-
i. Stage of Exudation
ii. Stage of Red hepatisation
iii. Stage of Grey hepatisation
iv. Stage of Resolution | Medicine | null |
ccb0fa34-a5f0-4130-a90e-5ad3b9e86baa | Most common Complication of TIPSS procedure | Heart failure | Hepatic Encephalopathy | Thrombosis | Recurrent Variceal bleed | 1b | single | Since systemic blood is shunted toxins ( NH3) travel to brain
causing encephalopathy. Hence TIPSS is contra indicated in
encephalopathy patients. | Surgery | null |
e5a36c5b-f3d3-4821-9b9a-95c359f2da7c | Schirmer's test detects abnormality of which nerve? | Oculomotor | Facial | Hypoglossal | Glossopharyngeal | 1b | single | (Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 389)*Schirmer's test is used for the production of tear by lacrimal glands*Preganglion secretory fibers for lacrimal gland arise from the lacrimatory nucleus and pass through the facial nerve, then to its greater petrosal branch. Greater petrosal nerve... | Ophthalmology | Diseases of orbit, Lids and lacrimal apparatus |
e25a3d49-8005-4414-b3ad-3f6f7afb586c | All except one is required for the diagnosis of obesity hypoventilation syndrome | Hypeension | Sleep disorder breathing | BMI more than or equal to 30 kg/m2 | PaCO2 more than or eqal to 45 mmHg | 0a | multi | Repeated | Medicine | Respiratory system |
158988b2-226d-405b-9a6b-cbaabf5bb35f | OCP are associated with which of the following complication (Repeat 2009) | Papilledema | optic neuritis | colourblindness | Papillitis | 1b | single | Ans b (Optic neuritis)Ophthalmic complication of OCP central retinal artery occlusion prethrombosis of central retinal vein perivasculitis, inflammation of anterior segment of the eye ' macular hemorrage Papillitis & lesions of optic nerve causing variable degree of visual loss | Surgery | Miscellaneous |
d92e085f-2ba7-492f-a16a-4501bc3bbb88 | Hydrogen sulphide acts on which complex of cytochrome oxidase | Comlex I | Comlex II | Comlex III | Comlex IV | 3d | single | Complex IV inhibitors i. Carbon monoxide, inhibits cellular respiration ii. Cyanide (CN-) iii. Azide (N3-) iv. Hydrogen sulphide (H2S)Ref: DM Vasudevan Textbook of Medical Biochemistry, 6th edition, page no: 234 | Biochemistry | Respiratory chain |
f9f4492a-f37a-4fa1-bd32-b3bd0d11c54e | Which structure lies midway between the ASIS & pubic symphysis : | Femoral aery | Deep inguinal ring | Superior epigastric aery | Inguinal ligament | 0a | single | A. i.e. Femoral aery Femoral aery traverses the femoral triangle from its base (which is formed by inguinal ligament - attached between ASIS and Pubic tubercle) at midinguinal pointQDeep inguinal ring lies 1/2 inch above midinguinal pointQ; Superficial inguinal ring lies I/2 inch bellow midinguinal point; and Saphenous... | Anatomy | null |
cea2d2a7-48c6-4d56-8338-b6634634b04b | First antibody to appear in hepatitis - | IgM anti-Hbe | IgG-anti-Hbe | IgM-anti-HBc | IgM anti-HBs | 2c | single | Anti-HBV appears in serum a week or two after the appearance of HBsAg. It is therfore the earliest antibody marker to be seen in blood? long before anti-HBe or anti-HBs. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-546 | Microbiology | Virology |
5fe7dbf2-be56-46fd-b6c2-b12c4d79bdc4 | In which of the following vasculitis lung involvement does not occur: | Eosoniphilic granulomatosis with vasculitis | Polyaeritis nodosa (PAN) | Microscopic polyangitis | Granulomatosis with polyangitis | 1b | single | Answer- B. Polyaeritis nodosa (PAN)Microscopic polyangiitis (microscopic polyaeritis, hypersensitivity, or leukocytoclastic vasculitis): This type of necrotizing vasculitis generally affects aerioles, capillaries, and venule.Wegener granulomatosis (Granulomatosis with polyangitis)- is a necrotizing vasculitis character... | Medicine | null |
0478a4df-b4ed-4f30-bf70-9784ed2bb589 | Which of the following drug is commonly used in narcoanalysis? | Atropine sulfate | Scopolamine hydrochloride | Phenobarbitone | Morphine | 1b | single | Ans. (B) Scopolamine hydrochloride(Ref: J Psychiatry and Law 1993:3:447-471)Controlled administration of intravenous hypnotics to obtain information from subjects who are unable or unwilling to provide it otherwise, is known as Narcoanalysis or Narcosynthesis.Drugs used for narcoanalysis are:[?]Ethanol[?]Scopolamine[?]... | Pharmacology | A.N.S. |
d5fb003c-5207-42ef-a555-7516354d027b | The function common to neutrophils, monocytes, and macrophages is: | Immune response is reduced | Phagocytosis | Liberation of histamine | Destruction of old erythrocytes | 1b | single | Phagocytic cells are: neutrophils monocytes macrophages | Pathology | Oxygen dependent bacterial killing |
b0b42625-73ea-4b87-982d-33420f1e3069 | Which of the following enzyme is involved in rejoining sho fragments of DNA on the lagging strand? | DNA Ligases | DNA Helicase | DNA Topoisomerase | DNA Polymerase | 0a | single | The okasaki fragments that are sho segments of DNA formed on the lagging strand of DNA in the 5'-3' direction are joined by DNA ligase. Ref: Textbook of Biochemistry By D M Vasudevan, 3rd Edition, Pages 347-8 | Biochemistry | null |
f410b51f-3c6d-4813-a290-b90540b2a917 | Ototoxicity caused by: | Vancomycin | Streptomycin | Ampicillin | Rifampicin | 1b | single | Ans. (b) StreptomycinRef : KDT 6th ed. / 743-44* Streptomycin has been assigned to pregnancy category D by the FDA.* Streptomycin crosses the placenta; reported cord concentrations have been equal to or less than the mothers serum concentration.* There are reports of fetal eighth cranial nerve damage with subsequent bi... | Pharmacology | Adverse Drug Effect |
11b617ed-2119-485a-a6b6-b4701529456f | The instrument below is used for | Endoscopic ultrasound probe | Oesophageal temperature probe | Enterography | None | 1b | multi | This is used for monitoring temperature, core temperature monitoring. | Anaesthesia | null |
ef6475d3-7f13-44c0-a443-675a5754893c | Alkalinization of urine is required to treat toxicity of all except: | Salicylates | Barbiturates | Amphetamine | Methotrexate | 2c | multi | Changes in urinary pH affect tubular reabsorption of drugs that are paially ionized - * Weak bases are ionize more and are less reabsorbed in acidic urine.* Weak acids ionize more and are less reabsorbed in alkaline urine. Urine is alkalinized in barbiturate, methotrexate and salicylate poisoning. | Pharmacology | Sympathetic System |
08d512d2-494a-4454-bf2e-d0100bc95982 | Which of the following is the feature of vegetations in Libmann Sacks endocarditis? | Large and fragile | Small way along the line of closure of valve | Small or medium sized on either or both sides of valve | Small bland vegetations | 2c | multi | Mitral and tricuspid valvulitis with small, sterile vegetations, called Libman-Sacks endocarditis, is occasionally encountered in systemic lupus erythematosus. The lesions are small (1 to 4 mm in diameter), single or multiple, sterile, pink vegetations with a way (verrucous) appearance. They may be located on the under... | Pathology | Endocarditis |
8f2c9083-567a-496a-a062-915cc9375280 | Permanent impairment of fingerprints occurs in all except | Leprosy | Acanthosis nigricans | Electrical injuries | Radiation injuries | 1b | multi | Permanent impairment of fingerprints occurs in: Leprosy Electrical injuries Radiation injuries Ridge alteration occur in: Acanthosis nigricans Scleroderma | Forensic Medicine | Human identification |
aa416fa4-aeec-4e1b-95c1-88dc92a4a753 | True about ascent to high altitude: | Respiratory acidosis | Polycythemia due to dehydration | Acute mountain sickness stas to develop on 7th day of ascent | Acetazolamide may be given prophylactically | 3d | multi | Respiratory alkalosis occurs Polycythemia is due to increased erythropoietin Acute mountain sickness develops 8-24 hr after arrival at altitude and lasts 4-8 days. Acute altitude illness: 3 forms Acute mountain sickness (AMS) The pathophysiology of AMS is not well understood. The essential factor responsible for this c... | Physiology | Respiratory System Pa 3 |
1c4fb007-eb04-4e88-bb9d-201e64917e61 | Phenol test or Reidel Walker test is done to determine: | Hardness of water | Chlorine demand | Quality of disinfectant | Efficacy of a disinfectants | 3d | single | Ans. d. Efficacy of a disinfectants | Microbiology | null |
e0ef61f7-b6e7-4ac1-aaba-5d1cf8269bc8 | The instrument shown here is useful for: | To condense amalgam | For vital bleaching | Removal of crown | Removal of broken instrument | 2c | single | null | Dental | null |
e6d005fa-9ea5-4df0-a98a-976aa3254954 | Goodpasture syndrome has antibodies against: | Collagen 1 | G-y or x-y of collagen | Collagen 4 | Collagen 2 | 2c | single | (Refer: Robbins Pathologic Basis of Disease, 8thedition, pg no: 709) | Unknown | null |
308aabb1-4d39-4afc-8059-f34033266ea2 | Zygote is dependent on which of the following for its nutrition - | Deutoplasm | Secretions from wall of fallopian tube and uterus | Sperm carbohydrate stores | All the above | 3d | multi | Ans. is 'd' i.e., All the above While zygote is passing down the fallopian tube and after a brief period as it enters the uterus, it depends for its nutrition on the yolk sac granules (deutoplasm) embedded in its cytoplasm and on the fluid medium surrounding it which is secreted by the walls of the uterine tube and ute... | Gynaecology & Obstetrics | null |
320cc577-5f62-4e6c-b5bd-f849fed7972c | Urine is collected for examination in a pregnant female by : | Mid stream collection | Suprapubic puncture | Catheterisation | Early morning sample | 3d | single | Early morning sample | Gynaecology & Obstetrics | null |
c26ebb3c-2829-447d-a540-1e885f643b75 | Okazaki fragments are found during | Replication | Translation | Translocation | Transcription | 0a | single | DNA synthesis is always into 5&; to 3&; direction in both strands The strand which is discontinuously synthesized is referred to as the &;lagging strand &; otherwise called the retrograde strand The small DNA molecules attached to its own primer RNA are called Okazaki fragments The synthesis along the lagging strand is... | Biochemistry | Metabolism of nucleic acids |
4c909f2f-cf54-49da-af5a-576474205b13 | Which type of pelvis is associated with increased incidence of 'face to pubis' delivery: | Gynaecoid pelvis | Anthropoid pelvis | Android pelvis | Platypelloid pelvis | 1b | single | As discussed in the text in Table 1.1 face-to-pubis delivery is common in anthropoid pelvis. | Gynaecology & Obstetrics | null |
e6913561-9a1a-4f1b-b774-c718f0624fdb | HIV primarily replications in which cells - | CD4T-cells | CD8 T-cells | Neutrophils | Follicular dendritic cells | 0a | single | Ans. is 'a' i.e., CD4 T-cells * The receptor for the virus is the CD4 antigen on surface. The cells affected are :# CD4 T Cells (major target)# B lymphocytes# Monocytes and macrophages# Langerhans cells in dermis# Glial cells and microglia in the CNS# Follicular dendritic cells from tonsils can be infected by HIV witho... | Microbiology | Virology |
02f45a16-1b7d-4bf5-a2b5-247ed39f7c33 | According to The Workmen's Compensation Act, 1923, which of the following is considered an occupational disease? | Typhoid | Anthrax | Tetanus | Dengue | 1b | single | Ans. b. Anthrax (Ref: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 0 8px; text-indent: 0">According to The Workmen's Compensation Act, 1923, Anthrax is considered an occupational disease.List of Occupational Diseases as per Employee Compensation Act 1923 (Workmen Compens... | Social & Preventive Medicine | Occupational Health |
3850e71b-d98e-4398-ac95-60b2491bcdb2 | Radiological factors indicating an unstable pelvis are all except: | Posterior sacroiliac complex displacement by > 1 cm | Avulsion fracture of sacral or ischial end of the sacrospinous ligament | Avulsion fractures of the L5 transverse process | Isolated disruption of pubic symphysis with pubic diastasis of 2 cm | 3d | multi | Radiographic factors indicating unstable pelvis are: Posterior sacroiliac complex displacement >1cm Avulsion fracture of sacral or ischial end of the sacrospinous ligament. Avulsion fractures of the L5 transverse process Disruption of pubic symphysis with pubic diastasis of 2 cm with posterior pelvic injury or injury t... | Orthopaedics | Pelvis and Hip Injury |
6b10406e-1a8e-4e0c-8af3-eac2af82bc68 | Angioid streak is seen in - | Tuberous sclerosis | Pseudoxanthoma elasticum | Sturge weber syndrome | Septo optic dysplasia | 1b | single | null | Medicine | null |
52887773-dea5-4c47-a834-89defe5a175b | Xiphoid process fuses with body of sternum by: | 10 years | 20 years | 30 years | 40 years | 3d | single | 40 years | Forensic Medicine | null |
9aa277e2-6952-40e5-986a-84c7b302b2dc | Uveitis is caused by –a) TBb) Staphylococcusc) Streptococcusd) Klebsiellae) E.Coli | ab | abc | acd | bcd | 1b | single | TB causes chronic granulomatous uveitis.
Staphylococcus and streptococcus cause acute non-granulomatous pyogenic uveitis. | Ophthalmology | null |
bfb3f73b-a7ef-4726-97a5-29715e7bda57 | A young female presented to you with primary amenorrhea. Examination reveals normal breast development and absent axillary hairs. Pelvic examination shows a normally developed vagina with clitoromegaly. On ultrasound, gonads are visible in the inguinal region. What is the most likely diagnosis? | Complete androgen insensitivity syndrome | Partial androgen insensitivity syndrome | Mayer Rokitansky Kuster Hauser syndrome | Gonadal dysgenesis | 1b | multi | Ans. is b, i.e. Partial androgen insentivity syndromeIn the question patient has 1deg amenorrhea:* Breast development is normal and absent axillary hair. (This means it cannot be Mayer Rokitansky kiister hauser syndrome --where Breast and pubic as well as axillary hair are well developed and it cannot be Gonadal dysgen... | Gynaecology & Obstetrics | Disorders in Menstruation |
a7580720-1bf3-4102-854b-63c89c138c62 | A patient presents with thrombocytopenia, eczema and recurrent infections. What is the most probable diagnosis? | Wiskott Aldrich syndrome | A beta gammaglobulinemia | Chediak higashi syndrome | Lazy leukocyte syndrome | 0a | single | Wiskott-Aldrich syndrome (WAS) is an X-linked platelet/immunologic disorder caused by mutations in the WASP gene. The triad of eczema, recurrent infections, and microthrombocytopenia that characterizes WAS only occurs in 27% of the cases. The immunologic defects include low serum concentrations of IgM, while IgA and Ig... | Medicine | null |
84797bc4-0406-4d41-a130-f79e456161ef | A baby presents with refusal to feed, skin lesions, seizures, ketosis organic acids in urine with normal ammonia; likely diagnosis is: | Proprionic aciduria | Multiple carboxylase deficiency | Maple syrup urine disease | Urea cycle enzyme deficiency | 1b | single | Baby in the above mentioned case scenario is showing signs and symptoms of multiple carboxylase deficiency such as dermatitis severe metabolic acidosis, organic acid excretion. Ref: Essentials of Pediatrics By Nelson, 16th Edition, Pages 356 ; The Embryo: Scientific Discovery and Medical Ethics By Shraga Blazer, Page 2... | Biochemistry | null |
ef7b70d9-9605-46ad-b894-73476befdceb | Carbamoyl phosphate intermediates the synthesis of | Urea | Urea & Pyrimidine | Uric acid | Ketone body | 1b | single | (B) Urea & Pyrimidine # Biosynthesis of urea begins with the condensation of CC>2, NHs and ATP to form carbamoyl phosphate, a reaction catalyzed by carbamoyl phosphate synthase I which is a mitochondrial enzyme, and rate limiting or pacemaker enzyme and the enzyme is active only in the presence of its allosteric activa... | Biochemistry | Miscellaneous (Bio-Chemistry) |
2eedf190-2cea-4a73-aace-fdbacd32e092 | Which of the following is not true about Diplococcus pneumoniae | Bile solubility | Optochin resistance | Causes Meningitis | Possess Capsule | 1b | multi | Streptococcus pneumoniae is optochin sensitive. Optochin sensitivity: the sensitivity of Streptococcus pneumoniae to optochin is useful in differentiating it from other streptococci. When a disc impregnated with optochin is applied on a plate of blood agar inoculated with Streptococcus pneumoniae, a wide zone of inhibi... | Microbiology | Bacteriology |
09e0a7d8-6a3b-41be-8200-b32900c38d06 | A patient on Bilonatumomab for refractory B cell All is now resistance to the drug. Which drug to be used:- | Vorinostat | Brentuximab | Pembrolizumab | Tisagenlecleucel | 2c | multi | Drug Mechanism Use Vorinostat HDAC inhibitor Cutaneous T cell lymphoma Brentuximab Man against CD30 Hodgkin lymphoma Pembrolizumab PD-1 Melanoma Lung Cancer Head and neck cancer Tisagenlecleucel Ca therapy ALL Blinatumomab Bispecific t-cell engages ( targets CD19 and CD3) ALL | Pharmacology | JIPMER 2019 |
9e307cf2-906c-4880-9c66-434b8ab8685f | Horizontal semicircular canal responds to | Horizontal acceleration | Rotational acceleration | Gravity | Antero-posterior acceleration | 1b | single | The three canals lie at right angles to each other but the one which lies at right angles to the axis of rotation is stimulated the most.Thus horizontal canal will respond maximum to the rotation on the veical axis. (Ref: Diseases of EAR, NOSE and THROAT by PL Dhingra; 6th edition; page no.17) | ENT | Ear |
088e94f6-ca40-4fef-9eac-904fd15c4ef9 | Roof of the Anatomical snuff box is formed by the | Radial aery | Basilic aery | Sup branch of radial nerve | Sup branch of ulnar nerve | 2c | single | Anatomical snuff box boundaries: Lateral wall Abductor pollicis longus Extensor pollicis brevis Medial wall Extensor pollicis longus Roof Cephalic vein Sup branch of radial nerve Floor Radial styloid, scaphoid, trapezium,1st meta carpal Content Radial Aery Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice ... | Anatomy | Upper limb |
90bb4a01-f48b-43fa-abbd-ebe7e3623b06 | Which of these differentiates between ante moem and post moem burns? | Heat rupture | Heat Hematoma | Soot paicles up to terminal bronchioles | Pugilistic attitude | 2c | single | SPECIFIC FINDINGS IN ANTEMOEM BURNS 1.SOOT PAICLES UPTO THE LEVEL OF TERMINAL BRONCHIOLE. 2. PRESENCE OF CARBOXYHEMOGLOBIN IN BLOOD. 3. Cyanide IN BLOOD 4. CURLING ULCER IN FIRST PA OF DUODENUM. NON SPECIFIC FINDINGS IN BURNS( ANTEMOEM + POSTMOEM BURNS) 1. PUGILISTIC ATTITUDE OR HEAT STIFFENING. 2. HEAT RUPTURE 3. HEAT... | Forensic Medicine | Thermal injuries |
32f2f0d1-4e17-41d9-9693-4a1db029239b | Arrange the following in sequential order of their involvement in estrogen synthesis: A. Progesterone B. Androgen in granulosa cell C. Androgen in theca cell D. Aromatase | B-A-D-C | A-C-D-B | D-C-A-B | A-C-B-D | 3d | single | Interaction of follicular theca and granulosa cells for production of estrogens. The theca cells, under the control of luteinizing hormone (LH), produce androgens that diffuse into the granulosa cells. In mature follicles, follicle-stimulating hormone (FSH) acts on granulosa cells to stimulate aromatase activity, which... | Physiology | Female Reproductive System |
e801f1ea-1424-46c2-8686-c9781521c7aa | Left bundle branch block (LBBB) on ECG can suddenly develop in all of the following except: | Acute MI | Ashman phenomenon | Hypokalemia | Hyperkalemia | 1b | multi | Ans. b. Ashman phenomenon (Ref: Harrison 18/e p1835) style="font-size: 1.04761904761905em; font-weight: bold; font-family: Times New Roman, Times, serif; margin: 0 0 0 8px; text-indent: 0">Ashman phenomenon:Ashman phenomenon is an intraventricular conduction abnormality caused by a change in the heart rate.Wide QRS com... | Medicine | Electrocardiography |
51d267cb-45d4-4357-961a-4b4b248bf988 | C-3 convertase in alternate complement pathway - | C4b2a | C3b | C3bBb | C3a | 2c | single | null | Microbiology | null |
4895947e-dd27-4326-a9cb-aa7b66c26380 | Treatment of latent TB infection in Tuberculin positive, HIV positive patients: | INH biweekly for 9 month | 2(HRZ)3 + 4(HR)3 | Rifampicin biweekly for 6 months | Pyrazinamide daily for 6 months | 0a | single | Ans. is 'a' i.e., 1NH biweekly for 9 month Dosing regimens for treatment of latent tuberculosis* AdultsChildren <12IsoniazidStandard regimen:o 300 mg PO daily for nine months Alternate regimens:o 300 mg PO daily for six months900 mg PO twice weeklyD for nine months900 mg PO twice weeklyD for six monthsStandard regimen:... | Medicine | Bacteriology |
40f0dcf9-4e03-4698-ba8d-7da048d6d0c7 | In MI, which enzyme is raised in 4 to 6 hrs. & decreases in 3 to 4 days : | SGOT | LDH | CPK | SGPT | 2c | single | Answer is C (Creatinine phosphokinase) Creatinine phosphokinase is seen at 4 to 8 hours (May be seen at 2-4 hours), peaks at 24 hours and return to normal by 72 hours. Creatinine phosphokinase MB (CPKMB) Very sensitive (CPK MB isoenzyme increases the specificity) 'Absence in change in levels of CPK and CPKMB during the... | Medicine | null |
466a0e38-82d4-45ca-8246-f1f5602a5730 | The most impoant factor in fracture healing is: | Good alignment | Organization of blood clot | Accurate reduction and 100% apposition of fractured fragments | Immobilisation | 3d | single | D i.e. Immobilization | Surgery | null |
62cde5f3-9df6-4dfa-ba6d-ee580e857c09 | Rubella causes all except | Microcephaly | VSD | PDA | AS | 3d | multi | Rubella: Rubella/ german measles is caused by RNA virus of togavirus family. Rubella inhibits cell division and this is the reason for congenital malformations. Congenital Rubella syndrome refers to infants born with defects secondary to intrauterine infections sometime after bih. It consists of triad of symptoms of de... | Pediatrics | Infectious disease |
03cd7e2f-3eba-43df-96f3-9276236534cf | Optical urethroplasty is done in:(Internet) | Congenital stricture of urethra | Hypospadias | Epispadias | Testicular tumour's | 0a | single | (Congenital stricture of urethra) (1388-89-Baily & Love 24th) (Internet) (1362-Baily & Love 25th)Hypospadias - surgical plastic repair of hypospadias is currently accomplished by a variety of highly successful one stage operations and is routinely performed between 6 and 19 months of age (1008-CSDT 12(tm))Epispadias - ... | Surgery | Urethra & Penis |
84cd2af8-2c2e-4e13-ab76-519ecce5fada | A 78-year-old man with advanced renal disease has the ECG(lead II). What is the diagnosis? | hyperkalemia | hypercalcemia | hypernatremia | pericarditis | 0a | single | (a) Source: (Fuster, p. 313)No atrial activity is detected. The ventricular rate is slightly irregular. Beat number 4 is a ventricular premature contraction. The T waves are tall and markedly peaked. This type of T wave is characteristic of hyperkalemia, as is absence of visible atrial activity. The potassium level was... | Medicine | C.V.S. |
14f553ed-7b5f-4421-b6fd-d71e33b8c8b2 | Acute changes in brain due to wernicke's encephalopathy in chronic alcoholics is most frequently seen in: | Mamillary bodies | Aqueduct of the midbrain | Around the third ventricle | Around the fouh ventricle | 0a | single | Acute changes are most frequently seen in the 1. Mamillary bodies And also seen in 2. Around the third and fouh ventricles and 3. Aqueduct of the midbrain. Ref: Thorarinsson BL, S C I E N T I F I C P A P E R O V E R V I E W | Medicine | null |
8ba2b730-39d7-41bc-af72-14a9097039e8 | Secondary oocyte consists of | 46 XY | 46 XX | 23 Y | 23 X | 3d | single | Ans. d (23 X)Secondary oocyte consist of 23 X chromosomes.The chromosomal complement of a primary oocyte is 46 XX and that of secondary oocyte is 23 X.Sequence of maturation of ovarian primordial follicle after primary follicle stage:Primordial follicle(Single layered ovarian follicle)Spermatogonium (diploid, 2N) ||Pri... | Gynaecology & Obstetrics | The Ovarian Cycle |
c4a55ae6-dbec-4b2d-a084-081118673a68 | True about mucosa associated lymphoma | H. Pylori predisposes | Chemotherapy sensitive | Multiple lymphomas | Stromal Polyp | 0a | multi | Gastric lymphoma This is a rare tumour, accounting for less than 5% of all gastric malignancies. The stomach is, however, the most common site for extranodal non-Hodgkin lymphoma and 60% of all primary gastrointestinal lymphomas occur at this site. Lymphoid tissue is not found in the normal stomach but lymphoid aggrega... | Medicine | G.I.T |
8563613e-ccc0-4b34-8458-39fadfcda3e9 | Which is not Glucogenic? | Arginine | HIstidine | Glycine | Lysine | 3d | single | The glucogenic amino acids are: Alanine Arginine Asparagine Aspaic Cysteine Glutamic Glutamine Glycine Histidine Methionine Proline Serine ValineRef: DM Vasudevan, 7th edition | Biochemistry | Metabolism of carbohydrate |
f24130de-63a8-4a78-9ccf-fb1c5a0993bb | The gene for folic acid transpoer is located on which chromosome: | 5 | 15 | 21 | X | 2c | single | C i.e. 21Folic acid transpoer gene (SLC 19 AI solute carrier family 19) is located on long arm of chromosome 21 (21q) Q at band 22.3. Transpo of folate occurs by potocytosis which functionally couples folate receptor, folate transpoer and V- type h+ pump. | Biochemistry | null |
51dd9041-40e1-49e3-8f3b-0983ead096f6 | The best treatment for class V lesion on a tooth along with extensive class II caries is: | Restoration of class II followed by class V | Cast gold restoration | A full crown restoration | Restoration of class V followed by class II | 2c | single | With class V lesion and extensive class II cavity in the same tooth the remaining enamel surface with the supported healthy dentin will be much less hence in such situation full crown restoration will be long lasting. | Dental | null |
7252503e-f6ba-44d0-a96c-e3bd9e355781 | Which has maximum nicotinic effect- | Bethanechol | Carbachol | Pilocarpine | Methacholine | 1b | single | Ans. is 'b' i.e., Carbachol o Amongst the given options carbachol has maximum nicotinic actions. It has nicotinic as well as muscarinic action. | Pharmacology | null |
a2f3cb49-a4fa-46d3-9743-bd1de0ca096e | Indications for cesarean hysterectomy are all except: | Placenta accreta | Couvelaire uterus | Atonic uterus with uncontrolled PPH | Rupture uterus | 1b | multi | Cesarean hysterectomy refers to an operation where cesarean section is followed by removal of the uterus.
Peripartum hysterectomy is the surgical removal of the uterus either at the time of cesarean delivery or in the immediate postpartum period (even following vaginal delivery).
Some indications for peripartum hystere... | Gynaecology & Obstetrics | null |
702f2177-19eb-46fc-a1e4-972372aaadf9 | The parasympathetic secretomotor nerve supply to the nose is | Anterior ethmoid nerve | Greater palatine nerve | Vidian nerve | Inferior orbital nerve | 2c | single | The nerve of the pterygoid canal passes through the pterygoid canal to reach the pterygopalatine ganglion. The parasympathetic fibres relay in this ganglion. Postganglion are parasympathetic fibres arising in the ganglion ultimately supply the lacrimal gland and the mucosal glands of the nose, palate, and pharynx. The ... | Anatomy | Head and neck |
bcb2dd5b-4db9-4cc5-a1b7-ce725cc2c324 | Foot process effacement is seen on EM in ? | Minimal change disease | Focal segmental GN | IgA nephropathy | All | 3d | multi | Ans. is All 'a' i.e., Minimal change disease, 'b' i.e., Focal segmental GN, 'c' i.e., IgA nephropathyo Foot process effacement is noted in patients with nephrotic syndrome.o A variety of injurious stimuli may cause the podocyte to react with flatteninng or simplification of the foot process architecture.While most comm... | Pathology | null |
57457e76-0ccb-4fe8-8ee7-05cbef9d1d7e | Most common organism associated with reactive arthritis is? | Staphylococcus | Shigella | Chlamydia | Yersinia | 2c | single | null | Medicine | null |
40d34782-f2cd-4463-a921-396b1260cd38 | Which of the following drug is category B (adequate studies in pregnant woman have failed to demonstrate a fetal risk)? | Ranitidine | Pilocarpine | Latanoprost | Dorzolamide | 0a | single | Category B drugus are the one that have shown no risks in animal studies, but human studies do not exist or also if adverse effect have been seen in animal studies with no such effect im well controlled human trials. eg.ranitidine,paracetamol. TEXT BOOK OF OBSTETRICS,Sheila Balakrishnan,2nd edition,page no.564 | Gynaecology & Obstetrics | Medical, surgical and gynaecological illness complicating pregnancy |
6ed150e0-6324-40a3-8bfb-b716a0175cb9 | Which of the following is true regarding Hybridoma Technique | It is a method for production of monoclonal antibodies | B Cells are fused with myeloma cells using polyethylene glycol | HAT medium is used to differentiate fused v/s unfused cells | All of the above | 3d | multi | All the following statements are corret. | Biochemistry | null |
dbe81316-be72-4dc9-b134-ee55072ac07b | Hu is defined under section: NEET 14 | 319 IPC | 320 IPC | 321 IPC | 323 IPC | 0a | single | Ans. 319 IPC | Forensic Medicine | null |
9d0fc292-fee0-4862-8e40-56b7128a6bb1 | Pale infarcts are seen at all of the following sites except- | Hea | Spleen | Kidney | Lung | 3d | multi | Ans is 'd' i.e., Lung INFARCTION o An infarct is an area of ischemic necrosis by occlusion of either the aerial supply or venous drainage in a paicular tissue. Pathogenesis o Mostly it is caused by interrupted blood supply. o "Nearly 99% of all infarcts results from thrombotic or embolic events and almost all result. f... | Pathology | null |
d250a721-a6c3-4c82-aef1-f19effcae5be | All are split - thickness skin graft except | Thiersch graft | Padgett graft | Wolfe graft | Blair-Brown graft | 2c | multi | Wolfe graft is full thickness skin graft. | Surgery | null |
42f67821-567d-464b-9ea9-c0f7153fd39c | Enteropathy type T cell lymphoma is associated with - | M.A.L. Toma | Celiac Sprue | Menetrier disease | Crohn's disease | 1b | single | Answer- B. Celiac SprueEnteropathy-type- T cell lymphoma is a rare complication of long-standing celiac disease. | Medicine | null |
4d7125b4-f5d7-4c00-a87b-8d2304559eb5 | Fine touch is transmitted via: | The dorsal lemniscal system | The anterior spinothalamic tract | The lateral spinothalamic tract | The cerebellopontine tracts | 0a | single | Ans. A. The dorsal lemniscal systema. Lateral spinothalamic tract carries pain and temperature;b. Anterior spinothalamic tract carries crude touch;c. All other sensations are carried by dorsal lemniscal. | Physiology | Nervous System |
63171850-88da-4d16-ad44-4419876674c0 | A young 25 year old man following A presented with proptosis (pulsatile in nature) ,chemosis and pain in right eye after 4 days. On Examination there was bruit on forehead and right eye. The probable diagnosis is | Cavernous sinus thrombosis | Carotico cavernous Fistula | Fracture sphenoid | Internal Carotid Aery Aneurysm | 1b | single | B i.e. Carotico cavernos Fistula | Ophthalmology | null |
c806d509-79be-4275-9b1e-b7155be25181 | BERA can be most accurate from which gestation? | 30 weeks | 32 weeks | 34 weeks | 28 weeks | 2c | single | Ref: Clohertys Manual of Neonatal Care, 6th edition. Page 646 and ENT DhingraExplanation:"ABR is reliable after 34 weeks postnatal age. "Ref: ClohertyBRAINSTEM EVOKED RESPONSE AUDIOMETRY (BERA)Other nameso Auditory brainstem responses (ABR)o Brainstem auditory evoked response (BAER)o Brainstem auditory evoked potential... | ENT | Hearing Loss |
4e5b932f-b4af-4520-a837-af06b82158dc | Parapharygeal space is also known as | Retropharyngeal space | Pyriform sinus | Lateral pharyngeal space | Pterygomaxillary space | 2c | single | Parapharyngeal space is situated on the side of the pharynx. It is pyramidal in shape with the base at the base of the skull and apex at the hyoid bone. It contains carotid vessels, jugular vein, last 4 cranial nerves and cervical sympathetic chain. Ref: Diseases of ENT, PL Dhingra, 7th edition, pg no. 301 | ENT | Pharynx |
98c3413d-8056-4956-9828-5beb051e2612 | A patient undergoing chest x-ray following an automobile accident is found to have an enlarged mediastinum with bilateral hilar and right paratracheal adenopathy. The patient has been asymptomatic, but careful examination demonstrates an enlarged cervical lymph node. This node is biopsied and demonstrates involvement b... | Anitschkow cells | Aschoff bodies | Asteroid bodies | Paget's cells | 2c | multi | The cells described are asteroid bodies, and are classically associated with sarcoidosis, although they are not completely specific for this disease. Anitschkow cells are a form of activated histiocyte with an unusual wavy chromatin. They are found within inflammatory lesions called Aschoff bodies in the heas of patien... | Pathology | null |
7cf95b23-c2c6-416b-8f04-1b61b0df3d2b | Which of the following is not true about Mumps: March 2007 | Caused by paramyxovirus | Incubation period is less than 14 days | Orchitis is a common complication in males | Aseptic meningitis is a commoner complication in children | 1b | multi | Ans. B: Incubation period is less than 14 Incubation period of mumps is 14-18 days The more common symptoms of mumps are: Parotid inflammation/ parotitis in 60-70% of infections. Fever Headache Orchitis, referring to painful inflammation of the testicle.Males past pubey who develop mumps have a 30 percent risk of orchi... | Medicine | null |
18f1f812-6c33-4640-904c-e533d07f8517 | All are true regarding Scheuermann's osteochondritis except? | Dorsal kyphosis | Autosomal recessive inheritance | Predominantly affects adolescent boys | Irregular ossification of veebral endplates | 1b | multi | Scheuermann's osteochondritis has autosomal dominant inheritance. It commonly affects adolescent boys. It is characterised by irregular ossification of veebral endplates and dorsal kyphosis. Most patients are asymptomatic. It can present with backache which is aggravated by exercise. Management is by protective postura... | Medicine | All India exam |
1e1f0e83-16ad-45bb-9fd1-7adfd47ef425 | Which among the following electrolyte disturbance following diarrhoea can cause convulsions? | Hypokalemia | Hyponatremia | Hyperkalemia | Hypernatremia | 1b | single | Hyponatremia can result from diarrhea, vomiting, burns, diuretic administration, and administration of sodium-poor parenteral solutions. Seizures and coma usually are associated with severe hyponatremia and may be life-threatening. Acute hypernatremia usually is caused by severe water depletion with diarrhea especially... | Medicine | null |
56e18036-e4d2-4a52-a9ce-f08fefc48044 | All are true about liver adenoma except | Normal liver architecture | Increased fat | Increased glycogen | Cells arranged in cords | 0a | multi | Clinical features Symptomatic ( upper abdominal pain) in 50-75%, related to hemorrhage or local compressive symptoms Two major risks - Rupture and malignant transformation Pathology Composed of cords of benign hepatocytes containing increased glycogen and fat, without bile ductules, fibrous septa, poal tracts or centra... | Anatomy | G.I.T |
a0dc8c41-3b9c-4eeb-871d-1b5e61e2a3b5 | First retinal abnormality in diabetic retinopathy: (PGI Dec 2007) | Microaneurysm | Hard exudates | Soft exudates | Cotton Wool spots | 0a | single | Ans. A (Microaneurysm) [Ref Khurana 4th/260-62; Parson 20th/294-98}"The earliest detectable lesion is microaneurysms in the macular area" -Khurana 4th/260Diabetic Retinopathy: Classification- 4 types Khurana 4th/260-62Non-proliferative Diabetic RetinopathyMicro aneurysmQ in macular area (the earliest detectable lesionQ... | Ophthalmology | Vascular Disorders |
12dea8d2-9238-4f16-9ce8-834e8edb8000 | Phase I trial is done to test: | Safety | Efficacy | Dose | Pharmacokinetics | 3d | single | Ans. D. PharmacokineticsPhase I trial is also called First in human trial. In this phase, 10-100 healthy people are enrolled to calculate pharmacokinetic data. Phase 0 trials are also done sometimes prior to phase I studies to calculate early pharmacokinetic data. Phase II and III trials usually enrol patients. Phase I... | Pharmacology | General Pharmacology |
b0ab3da2-ad8d-408e-9b8e-6b7ae22ce811 | New infectious agents are - | Nipah virus | Pneumocystis jieruveci | Corona virus | SARS | 0a | single | A new genus Henipavirus has been recently identified with the Nipah and Henda viruses causing zoonotic outbreaks. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO:515 | Microbiology | Virology |
5292a5ee-7e19-426f-b0a4-20a07af51d58 | All of the following are tumor markers, except | CEA | HCG | Alpha-fetoprotein | Beta-2 macroglobulin | 3d | multi | Beta-2 microglobulin and not beta macroglobulin may be used as a tumor marker (as in multiple myeloma). | Pathology | null |
f14ddf6b-2f16-435a-9904-ad144bb3f411 | Felty syndrome is characterised by A/E | Rheumatoid ahritis | Splenomegaly | Neutropeni | Thrombocytopenia | 3d | single | Ans. is 'd' i.e., Thrombocytopenia Felty's syndrome is characterized by the combination of rheumatoid ahritis, splenomegaly and neutropenia. The condition is more common in those aged 50-70 years, and is more prevalent in females than males | Pediatrics | null |
52f4ab9b-7c18-4f58-897a-a54c73703718 | Inversion of foot is at | Talocalcaneonavicular joint | Calcaneocuboid joint | Talocalcaneal joint | Inferior tibiofibular joint | 2c | single | C. i.e. Talocalcaneal joint | Anatomy | null |
a6a7bf87-ad7b-4df1-aace-9c360b80df9f | The motility of cell is due to protein- | Motilin | Tubulin | Laminin | Tactilin | 1b | single | Functions of Microtubules include determination of cell shape and various cell movements. | Physiology | null |
241d2385-b917-4893-a7d9-7dad39f89f9b | After the first postoperative year of cardiac transplantation, the most common cause of death is | Infection | Arrhythmia | Accelerated graft arteriosclerosis | Acute rejection episode | 2c | single | Chronic graft rejection is manifested in cardiac allografts as chronic vascular rejection of main and intramuscular coronary arteries. Myointimal proliferation and medial scarring result in diffuse and eccentric arterial narrowing referred to as accelerated graft atherosclerosis. Infection remains the primary cause of ... | Surgery | Transplantation |
d51356ac-476d-49be-a4ee-ac604b7f9294 | Shape memory is seen in: | Stainless steel wire | NITINOL wire | TMA wire | Aluminium | 1b | single | null | Dental | null |
8ba15321-64eb-47d5-8b73-6e9e087a39bc | Thyroid carcinoma associated with hypocalcemia is | Follicular carcinoma | Medullary carcinoma | Anaplastic carcinoma | Papillary carcinoma | 1b | single | Answer is B (Medullary Carcinoma) Medullary carcinoma of thyroid secretes calcitonin and this causes reduction in calcium levels. | Medicine | null |
5a3925fa-6a7d-4689-bbeb-469a5ca13630 | Fetal abdominal circumference is measured at the level of : | Stomach and umbilical vein, perpendicular to spine | Kidneys | Stomach parallel to spine | Liver and spleen | 0a | multi | Abdominal Circumference (AC) is measured in the transverse section of the fetal abdomen at the level of the fetal stomach and the umbilical poion of the poal vein.This is usually affected in IUGR and is less useful in dating as it is the parameter most affected by fetal growth. Refer page no 479 of Text book of obstetr... | Gynaecology & Obstetrics | Diagnosis in obstetrics |
61450be5-7374-42fb-9508-c16293fe3349 | A 16 year old boy presented with asymptomatic, multiple erythamatous annular lesions with a collarette of scales at periph-ery of the lesions present on the trunk. The most likely diagnosis is: | Pityriasis versicolor | Pityriasis alba | Pityriasis rosacea | Pityriasis rubra pilaris | 2c | single | C i.e. Pityriasis rosea Pityriasis rosea is a self limiting disorderQ of unknown etiology, with a suspected association with Herpes virus 7 and 6Q. It presents with development of usually asymptomatic (i.e. no prodromal or constitutional system), sharply (well) demarcated, larger (2-6 cm), annular (oval-round), erythem... | Skin | null |
d887e299-72d5-4912-a90b-1a0450dd1038 | Which of the following is a stain for fat cells? | PAS | Prussian blue | Sudan IV | Alcian blue | 2c | single | ANSWER: (C) Sudan IVREF: See APPENDIX-24 for "HISTOLOGY/PATHOLOGY/ MICROBIOLOGY STAINS" APPENDIX - 24Histology/Pathology/Microbiology StainsT issue/substanoeStainCommentAmyloidGross stainingLugol's iodine Light microscopyH & E, Congo redPolarised lightCongo redMetachromatic stainMethyl violet, crystal violetFluorescent... | Pathology | Histo Pathology |
723f2290-a389-4c86-b783-77fb1727c225 | In a person with HIV-1 infection, which of the following is the most predictive of the patient's prognosis | CD4+ cell count | CD4:CD8 cell ratio | Level of HIV-1 RNA in plasma | Degree of lymphadenopathy | 2c | single | Amplification assays (-PCR, DNA PCR, and b DNA tests) are routinely used to detect viral RNA in clinical specimens. The tests can be quantitative when reference standards are used, and appropriate positive and negative controls must be included in each test. Because these molecular based tests are very sensitive, they ... | Microbiology | Virology |
85d93505-5b85-4514-ac9d-183a88365c70 | All of the following are biochemical markers included for triple test except | Alfa-fetoprotein | Human chorionic gonadotropin (hCG) | Human placental lactogen (HPL | Unconjugated oestriol | 2c | multi | Triple test It is a combined biochemical test which includes MSAFP,hCG,UE3(unconjugated oestriol).Maternal age in relation to confirmed gestational age is also taken into account.It is used for the detection of Down&;s syndrome.In an affected pregnancy,level of MSAFP and UE3 tend to be low while that of hCG is high.It ... | Gynaecology & Obstetrics | Diagnosis in obstetrics |
edbfe6fe-21c2-4743-98c2-e0c7426c7a9d | Maximum collagen in wound healing is seen at which stage of healing | End of first week | End of second week | End of third week | End of 2months | 2c | single | ref Robbins 9/ep106-108 When the levels of collagen production and degradation equalize, the maturation phase of tissue repair is said to have begun. During maturation, type III collagen, which is prevalent during proliferation, is replaced by type I collagen.Originally disorganized collagen fibers are rearranged, cros... | Anatomy | General anatomy |
ac0b04af-936c-4c5f-b4ac-507813dd5b38 | Elective endodontic treatment is contraindicated in | Angina patients | Recent MI | Diabetes | Hypertension | 1b | single | null | Dental | null |
dc27b944-65da-4b63-a642-9884cb520e38 | Which of the following is not a High Risk Characteristic in proliferative diabetic retinopathy | NVD >= 1/3 - 1/2 disc area | NVD + Vitreous or Preretinal haemorrhage | NVE >= 1/2 disc area and Preretinal or Vitreous haemorrhage | NVD + Clinically signifacnt macular edema | 3d | multi | Proliferative Diabetic Retinopathy Early PDR- Presence of new vessels High risk PDR NVD >= 1/3 - 1/2 disc area or NVD and Vitreous or Preretinal haemorrhage or NVE >= 1/2 disc area and Preretinal or Vitreous haemorrhage | Ophthalmology | Retina |
d02718fd-e241-4256-ae93-467655317154 | Normal aqueous production rate - | 2 ml/min | 5 ml/min | 2ml/min | 5 ml/min | 2c | single | Aqueous humour is derived from plasma within the capillary network of ciliary processes.The normal aqueous production rate is 2.3ml/min. Ref:ophthalmology -AK khurana -6th edition chapt:10 page no:221 | Ophthalmology | Glaucoma |
4f8f7930-288a-452d-8d93-86a9bd6aede3 | Ex-Press giaueoma implant is oiaily up of: | Silicone | Titanium | Gold | Stainless steel | 3d | single | Ans. d. Stainless steel | Ophthalmology | null |
010d3612-2353-4694-8d3a-9d3086dcb8bb | A 45 year - male presents with abrupt onset pain, weakness, loss of contour of shoulder and muscle wasting on 5deg day of tetanus toxoid immunization. Likely cause is: | Hysterical | Radial nerve entrapment | Brachial plexus neuritis | Thoracic outlet syndrome | 2c | single | Brachial plexus neuritis Ref: Basic neurology [By John Gilroy 3/e p594; "Brachial plexus neuritis is characterized by a sudden paralysis of muscles supplied through the brachial plexus and is often associated with painful dysesthesia of the arm. The condition occurs in known viral infections (herpes zoster, Epstein-Bar... | Anaesthesia | null |
e875b62b-33c2-4832-9185-bb14d29d14d2 | MOST common acute complication of hemodialysis is: | Muscle cramps | Anaphylaxis | Hypotension | Arrythmias | 2c | single | Hypotension is the most common acute complication of hemodialysis. It is paicularly common among patients with diabetes mellitus. The factors that appear to increase the risk of hypotension, are excessive ultrafiltration with inadequate compensatory vascular filling, impaired vasoactive or autonomic responses, osmolar ... | Medicine | null |
261a31e5-a2c6-43c1-a968-36d399308efb | Which of the following decreases effectiveness of insulin - | Thiazide | Atropine | b-blockers | Acute alcohol ingestion | 0a | single | Ans. is 'a' i.e., Thiazide o Thiazide, furosamide, coicosteroids, oral contraceptives, salbutamol, nifedipine tend to raise blood sugar and reduce effectiveness of insulin. | Pharmacology | null |
290a5141-1ac6-4b40-a494-9d5cbc80bb77 | Causes of exudative retinal detachment are all except - | Toxemia of pregnancy | Scleritis | High myopia | Central serous retinopathy | 2c | multi | Occurs due to the retina being pushed away by a neoplasm or accumulation of fluid beneath the retina following inflammatory or vascular lesions. Etiology: Systemic diseases- toxaemia of pregnancy, retinal HTN, blood dyscrasias. Ocular diseases- scleritis, central serous retinopathy, orbital cellulitis, retinoblastoma, ... | Ophthalmology | Vitreous and retina |
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