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135
75361554-bcf9-48ca-a6be-bd1f36211767
The structure marked A begins to close by what time frame and due to what cause?
Begins to close at 10-15 hours after bih, due to withdrawal of prostaglandins
Begins to close at 10-15 hours after bih, due to expression of prostaglandins
Begins to close 4 weeks after bih, due to fall in oxygen concentration
Begins to close 4 weeks after bih, due to rise in oxygen tension
0a
multi
The structure marked is ductus aeriosus which begins to close 10-15 hours after bih due to withdrawal of prostaglandins and exhibits functional closure by 7 days and anatomical closure by 4 weeks after bih.
Anatomy
Pharyngeal arch and its derivatives, pharyngeal arch aeries
6b8e3222-0786-460d-93a5-33c32e4f0f20
All are indicated in a 30-year-old patient with increased serum cystine and multiple renal stones except:
Cysteamine
Increase fluid intake
Alkalinization of urine
Penicillamine
0a
multi
The clinical diagnosis of profile given in the question is CYSTINURIA . Cystinuria- AR,defect in re-absorptive transpo of cystine and the dibasic amino acids ornithine, arginine, and lysine from the luminal fluid of the renal proximal tubule and small intestine. Urinalysis- hexagonal shaped crystals: pathognomonic of c...
Medicine
Kidney Stones & Renal Tubular Acidosis
ac6a6959-3139-431c-b49c-23b2a534bca9
A Ten year old boy presents to the pediatric emergency unit with seizures. Blood pressure in the upper extremity measured as 200/140 mm Hg. Femoral pulses were not palpable. The most likely diagnosis amongst the following is:
Takayasu Aooaeritis
Renal parenchymal disease
Grandmal seiures
Coarctation of Aoa
3d
single
Answer is D (Coarctation of Aoa) Isolated upper extremity hypeension (200 / 140 mm Hg), together with absent/ diminished femoral pulses is a characteristic feature of coarctation of aoa. Although coarctation of aoa does not commonly present with seizures, these may be seen as a consequence of severe hypeension (BP = 20...
Medicine
null
da3737ee-4035-41c4-8fa9-bdc1ac3f35ee
A 30 year-old male has jaundice. Blood examination shows total serum bilirubin 28 mg%, direct bilirubin 16 mg % and alkaline phosphatase 184 KA units. The Diagnosis is :
Haemolytic jaundice
Viral hepatitis
Chronic active hepatitis
Obstructive jaundice
3d
single
Answer is D (Obstructive jaundice): The patient in question has high conjugated bilirubin levels (direct bilirubin > 50% of total bilirubin), along with alkaline phosphatase levels more than 6 times normal. The answer of choice therefore is obstructive jaundice. Approach: If direct conjugated bilirubin is greater than ...
Medicine
null
f9d78211-6d8a-49fb-88da-ac7d4e023143
In differential diagnosis of lump in right fornix which is not true :
Ovarian cyst
Hydro salpinx
Appendicular mass
Submucosal fibroid
3d
multi
Submucosal fibroid
Gynaecology & Obstetrics
null
cff87108-acda-4a48-94dd-d1c9ddf0d7cb
A patient presents with symptoms of Hypoglycemia. Investigations reveal decreased blood glucose and increased Insulin levels. C-peptide assay is done which shows normal levels of C- peptide. The most likely diagnosis is:
Insulinoma
Accidental sulfonylurea ingestion
Accidental exogenous Insulin administration
Accidental Metformin ingestion
2c
single
Answer is C (Accidental exogenous Insulin administration): Normal / Reduced levels of C- peptide in the presence of increased insulin suggest a diagnosis of exogenous insulin administration as the cause of hypoglycemia. Approach to a patient with Hypoglycemia and Increased Insulin levels: Role of C- peptide Assay Norma...
Medicine
null
ec79e14c-1a38-43cf-84fb-4752981c0598
Methemoglobinemia may be caused by all of the following drugs, EXCEPT:
Sulfonamides
Phenytoin
Phenacetin
Nitrobenzenes
1b
multi
Drugs causing methemoglobinemia are: Nitrous gases, chloroquine and primaquine, phenazopyridine, sulfonamides, sulfones, aniline dye derivatives, phenacetin, dapsone, local anesthetics, and nitrobenzenes. Hemoglobin becomes methaemoglobin when iron is oxidized from the ferrous to the ferric form. This conversion of hem...
Pharmacology
null
da8bd45b-e1f3-41b9-96ea-ae837913c481
A patient came with abduction limitation of right eye and horizontal diplopia. Which nerve can possibly be paralyzed
2nd Nerve
3rd Nerve
4th Nerve
6th Nerve
3d
single
Lateral rectus Palsy 1. Lesion of Abducens nerve 2. Abduction limitation due to paralysis of lateral rectus 3. Convergent squint and diplopia (horizontal) on long standing palsy. 4. Patient present with turn towards the side of affected muscle Associations Millard Gubler syndrome: Ipsilateral 6th nerve palsy with contr...
Ophthalmology
Squint
228bafe6-feeb-4a22-aee1-30a74d77f82f
Most common cause of acute parotitis -
S. Aureus
S. Pneumonia
Klebsiella
S.Viridans
0a
single
Ans. is 'a' i.e., Staph Aureus o MC organism is staph aureus >> str. viridans >> pneumococcus.
Surgery
Miscellaneous (Salivary Gland)
fb17cf14-861c-4af4-a01b-118ab4f4d017
The most commonly affected tissues in neurocysticercosis is -
Brain
Eye
Muscles
Liver
0a
single
Larvae penetrate the intestine -MC sites of deposition in- CNS (60-90%)> Eye > muscle. in CNS - subarchanoid >parenchymal Option 1, 2, 3, 4 Cysticercosis: Caused by T. solium (Pork tapeworm) Potentially dangerous systemic disease. Neurocysticercosis (NCC) NCC: MC parasitic CNS infection of man and MC cause of adult ons...
Microbiology
Parasitology Pa 2 (Helminthology)
69cfb017-9078-4e30-b6c4-69cafa632abb
Which scientific principle is the basis for thermodilution method used in measurement of cardiac output by pulmonary catheter?
Hagen-Poisseuile principle
Stewart-Hamilton equation
Bemouli's principle
Universal Gas Equation
1b
single
Ans. b. Stewart-Hamilton equation (Ref: Ganong 23/e p513; Guyton 11/e p244)Stewrt-Hamilton equation is the basis for thermodilution method used in measurement of cardiac output by pulmonary catheter.Stewart Hamilton equationThe thermodilution technique has become the de-facto clinical standard for measuring cardiac out...
Physiology
Circulation: Cardiac Output, Venous Return
de8f938e-9794-4459-bf6f-0d7818667884
Which of the following muscle lies between superficial and deep pas of submandibular salivary gland?
Hyoglossus
Styloglossus
Mylohyoid
Geniohyoid
2c
single
Submandibular gland is a large salivary gland situated in the anterior pa of the digastric triangle. It is roughly J-shaped,being indented by the posterior border of the mylohyoid which divides into a larger pa superficial to the muscle,and a small pa lying deep to the muscle. Reference: B D Chaurasia's human anatomy; ...
Anatomy
Head and neck
f2fc8bc4-3e9c-4d2e-8316-2e96bfdf31be
Inhibition of protein synthesis in translation phase is: due to
Isoniazide
Ethambutol
Methotrexate
Cycloserine
0a
single
null
Biochemistry
null
4a209f8b-1317-4a45-94bf-83f4b6fd71d3
Most common cause of chronic pancreatitis:
Gallstones
Alcohol
Trauma
ERCP
1b
multi
Ref. API Textbook of Medicine. Pg. 815   Chronic pancreatitis is a chronic inflammatory disease in which there is irreversible progressive destruction of pancreatic tissue Its clinical course is characterized by severe pain and in the later stages, exocrine and endocrine pancreatic insufficiency . High alcohol consump...
Unknown
null
7a837c27-fb28-48ce-bbe0-1eb06db11273
Compliance curve of the lung given below. Curve A signifies which of the followings:
Pulmonary fibrosis
Atelectasis
Emphysema
ARDS
2c
single
Compliance is defined as the change in volume for a unit change in pressure. It measures the distensibility or, stretchability of lung The total compliance of both lungs together in the normal adult human averages about 200 milliliters of air per centimeter of water transpulmonary pressure. The compliance of the combin...
Physiology
Respiratory System
8169afad-2086-4bde-b413-a4dea8d49321
Which of the following nerves carries taste sensation from posterior one-third of the tongue:
Facial nerve
Chorda tympani
Glossopharyngeal nerve
Vagus nerve
2c
single
The Glossopharyngeal nerve is the nerve for both general sensation and taste sensation for the posterior 1/3rd of the tongue including the circumvallate papillaeNerve supply of tongueMotor supply: All the intrinsic muscles, except the palatoglossus are supplied by the hypoglossal nerve (The palatoglossus is supplied by...
Anatomy
null
9a61d711-1a82-4bdf-ad0c-1a1985e26ee0
All of the following are true about the Right Coronary Aery (RCA) except___
RCA diameter is less than left coronary aery
RCA arises from the anterior aoic sinus
RCA gives rise to circumflex coronary branch
Right Coronary aery is the first branch of RCA
2c
multi
The right coronary aery arises from the anterior aoic sinus (Right coronary sinus) of the ascending aoa. (Option B) It passes anteriorly and descends veically in the coronary sulcus between the right atrium and the right ventricle. On reaching the inferior margin, it turns posteriorly and continues in the sulcus on to ...
Anatomy
All India exam
2ee35b19-619b-4ea1-a997-5593a2cda11e
Most common malignant lesion of the eyelid is
Squamous cell carcinoma
Basal cell carcinoma
Malignant melanoma
Adenocarcinoma
1b
single
Basal cell carcinoma This is usually a slow-growing, locally-invasive, malignant tumour of pluripotential epithelial cells arising from basal epidermis and hair follicles; hence, it affects the pilo-sebaceous skin. EPIDEMIOLOGY The strongest predisposing factor to BCC is UVR. It occurs in the elderly or the middle-aged...
Surgery
Urology
db3c5c93-ebc6-47d3-887e-8061f01bbd9c
ANA seen in SLE is directed against?
dsDNA
mRNA
Nucleolus
Ribosomes
0a
single
“Antibodies to double-stranded DNA and the Smith (Sm) antigen are virtually diagnostic of SLE" ---------- Robbins Antinuclear antibodies in SLE 1) Generic antinuclear antibodies (ANA) □ These are most common (93-100% of patients), thus are most sensitive antibodies for SLE (best screening test). 2) Anti-dsDNA and Anti-...
Pathology
null
5d9cf11b-6a91-4b3f-8deb-be30bdc6d88e
In cellular event of acute inflammation all are seen except -
Compliment involved in chemotaxis
ICAM - adhesion of leukocytes
PECAM - Activation of leukocytes
Selectins - Margination & rolling
2c
multi
. PECAM &; Activation of leukocytesExplanation :- PECAM 1 (platelet endothelial adhesion molecule) or CD31 &; involved in migration of leukocytes
Pathology
null
7cffb021-2110-41d1-963f-50936f881550
A 76 year old male with a history of dyspnoea on exeion was subjected to x-ray chest by the treating physician. The findings on the chest X-ray are given below. There is a history of fever with significant loss of weight and occasional bloody diarrhoea for the past 3 months. What is the most likely diagnosis?
Disseminated tuberculosis
Colon cancer with lung metastasis
Amebic liver abscess with rupture
Squamous cell carcinoma lung
1b
single
This is an X-ray film showing multiple cannonball metastasis in the lung. The following neoplasms are most likely to spread to the lungs. Given the history it is likely to be a colorectal carcinoma. Melanoma Thyroid cancer Breast cancer Colorectal cancer Head and neck cancer Renal cell cancer Choriocarcinoma Testicular...
Radiology
null
1bb0f11e-a9d9-448e-a43c-f3a9483a93d5
A 21 years female of 143 cm height present primary amenorrhea, absent breast, Cubitus valgus. Most probable diagnosis is?
Turner's syndrome
Mixed gonadal dysgenesis
Mayer Rokitansky kuster Hauser syndrome
Androgen insensitivity syndrome
0a
single
Individuals with Turner's syndrome are phenotypic females with primary amenorrhea, absent secondary sexual characteristics, sho stature, multiple congenital anomalies, and bilateral streak gonads. Characteristic Findings in Women with Turner Syndrome: Height 142-147cm Micrognathia Epicanthal folds Low-set ears Sensorin...
Gynaecology & Obstetrics
null
5bb4ab2c-e273-4826-94f8-4ace92150b77
WHO ORS contains -
Sodium chloride 2.5 g
Potassium chloride 1.5 g
Glucose 20g
Shift of water from ECF to ICF
1b
single
Ans. is 'b' i.e., Potassium chloride-1.5 gm Because of the improved effectiveness of reduced osmolarity ORS solution, WHO and UNICEF are recommending that countries manufacture and use the following formulation in place of the previously recommended ORS solution.
Pediatrics
null
1d59dd69-b8cc-4f7e-baaa-21447e735f49
DNA replication and transcription occurs in which direction -
51-31
5l-51
31 -51
31 -31
0a
single
Ans. is 'a' i.e., 51 - 31 Elongation in DNA synthesiso Once the RNA primer has been synthesized at each of the replicating forks, a DNA polymerase III initiates the synthesis of new DNA strand by adding deoxyribonucleotides to the 31 end of RNA primer. Thus, both new strands are synthesized always in 51- 31 direction. ...
Biochemistry
DNA Replication
4e292c52-99ef-4c2d-ac8d-e089ef9711e6
Sympathetic ophthalmitis is due to
Blunt trauma
Penetrating trauma
Chemical injury
Retained intra ocular Iron foreign body
1b
single
Sympathetic Ophthalmitis* Bilateral granulomatous panuveitis after penetrating trauma with prolapsed of uvea* Injured eye - exciting eye; normal fellow- sympathizing eye* Causes: penetrating injury, intraocular surgeries, cyclophotocoagulation, cyclocryotherapy* Site of injury: involving CB, iris and lens capsule* Path...
Ophthalmology
Ocular Trauma
509d3a6b-c998-4898-b72b-59f4e308bbc0
Best test to quantify' feto-maternal haemorrhage in Rh isoimmunisation is -
LPT
DCT
Kleinhauser test
Indirect coombs
2c
single
Ans. is 'c' i.e., Kleinhauser test Kleiheaur betke testo It is quantitative test which is used to calculate the approx volume of the fetal blood entering into the maternal circulation. Based on the principle of acid elution technique and is done by using citric acid phosphate buffer. Fetal red cells (dark refractile bo...
Gynaecology & Obstetrics
Pregnancy in Rh-negative Women
f84822b1-ddbb-4b46-9074-c924e5278583
Collagen found in hyaline cailage is
Type I
Type II
Type IV
Type V
1b
single
Collagen present in cailage are chemically distinct from those in most other tissues.They are described as type 2 collagen Inderbir Singh&;s textbook of human Histology Seventh edition Pg no 82
Anatomy
General anatomy
8a281141-376a-436b-88ea-471b882711d7
A 60 year old male patient complains of food lodgment in upper right back teeth region. Patient gives h/o RCT with 16 and extraction with 15. Ceramic crown and bridge was planned. Which of the following is not a method for strengthening this restoration?
Thermal tempering
Maximizing the number of firing cycles
Ion exchange
Development of residual compressive stresses
1b
single
-DEVELOPMENT OF RESIDUAL COMPRESSIVE STRESSES The fabrication of metal-ceramic and all-ceramic prostheses usually involves sintering the ceramic at high temperature or hot-pressing a veneering ceramic onto the metal or core ceramic. The process of cooling to room temperature offers the opportunity to take advantage of ...
Dental
null
a846cbec-96ae-47a5-b359-0879c09aff59
A 23-year-old female presents with an itchy, linear rash on her foot. She returned from a camping trip 4 days ago and denies using any new makeup, clothing, or jewelry. True about this skin pathology:
Type II hypersensitivity reaction
More common in children than in adults
Usually pruritus is absent
Treatment is with coicosteroids
3d
multi
Diagnosis - Contact dermatitis. Foot lesions are erythematous papules and vesicles with serous weeping. Lesions localized to areas of contact with the offending agent (the foot ware in this case). Treatment: Topical or systemic coicosteroids & cool, wet compresses
Dental
Eczema and related disorders
0f01c6be-ef38-47c8-9e42-858ce3dc3f69
Treatment of choice of Kawasaki disease ?
IV immunoglobulin
Steroid
Azathioprin
Not recalled
0a
multi
Kawasaki disease is a vasculitis that mostly involves the coronary vessels. It presents as an acute systemic disorder, usually affecting children under 5 years.Kawasaki's disease is an acute, febrile, multisystem disease of children. Some 80% of cases occur prior to the age of 5, with the peak incidence occurring at <=...
Medicine
Immune system
c66b51d2-3197-45f8-b7e0-18ddd5b80168
When restoring a tooth with resin material, acid etching can do all of the following except
Increase the surface area
Permit chemical bonding between resin and enamel
Create surface irregularities in enamel for better mechanical retention of resin
Condition the tooth surface for better wetting
1b
multi
null
Dental
null
73efa318-a118-4e3e-8bad-3b2124250b99
A 35 year old female, hospitalized after a motor vehicle accident, develops acute gastric stress ulcers. Increases in which of the following normal physiological parameters may have contributed to this condition?
Bicarbonate transpo
Epithelial regenerative capacity
Mucosal blood flow
Pepsin production
3d
single
Pepsin production is a normal physiologic activity of the stomach that, in conditions of stress, may overwhelm the stomach's weakened defenses and result in gastric ulceration. Gastric acid production is another condition that may increase and cause acute ulceration. Fuhermore, these two factors may remain unchanged an...
Physiology
null
2e97b7e2-acc1-495c-b581-b3b7c935577f
Which of these is characteristic of amyloidosis-
Beta pleated, metachromosis, PAS + ve
Congophilic, beta pleated, PAS +ve
Beta pleated, fibrillary, congophilic
Alpha pleated, small fibrils
2c
multi
Robbins and Cotran pathologic basis of disease South Asia edition. *by electron microscopy all types amyloid consist of continuous non branching fibrills.X Ray crystallography and infrared spectroscopy demonstrate a characteristic cross-beta-pleated shear conformation .this conformation is responsible for distinctive C...
Pathology
General pathology
20bb0d70-4d3b-4d33-bf8f-e83625c4ab2c
What is the intermediate host of the organism shown here?
Snail
Cyclops
Pig
Mosquito
1b
single
organism-Guinea worm/medina worm/serpent worm habitat- subcutaneous nodules DH-humans IH- cyclops(lobsters, crabs shrimps) MOI-ingestion of drinking water containing cyclops infested with L3Larvae
Microbiology
Parasitology Pa 2 (Helminthology)
dc874841-182d-4a6e-b5f8-ba9aa6e427e0
Following is true about longitudinal studies
Used to study the natural history of the disease
Single outcome
Are economical
Are efficient
0a
multi
Longitudinal studies are useful in: To study the natural history of disease and it's future outcome For identifying risk factors of disease For finding out incidence rate or rate of occurrence of new cases of disease in the community Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 78
Social & Preventive Medicine
Epidemiology
72af96a1-0a0d-4a54-bc08-53a338572dbd
What is the indication for therapeutic thoracocentesis?
Free fluid separates the lung from chest wall by 10 mm
Loculated pleural fluid
Recurrence of pleural fluid < 72 hours of previous thoracocentesis
Mesothelioma
0a
multi
Therapeutic thoracocentesis- Indication - Free fluid separates the lung from chest wall by 10 mm Measured radiographically Preferred site of thoracocentesis -7th ICS Scapular line. For Recurrent pleural effusion - pleurodesis. In pleurodesis we inject a sclerosing agent in pleural space which causes obliteration of ple...
Medicine
Pleural effusion & Pulmonary alveolar proteinosis
dfaa4327-bc95-4b02-b2a3-93baed357088
The major difference between X-Rays and Light is:
Energy
Mass
Speed
Type of wave
0a
single
The main difference between an X-ray photon and a visible light photon lies in the energy of each photon. Xray photon has approximately 5000 times the energy of an ordinary light photon, allowing the Xray photon to pass through materials more readily than a regular light photon. Ref: Techniques in Microscopy for Biomed...
Radiology
null
cf225b0b-9e41-4f41-9e6a-55d6bd10e2a7
Structure NOT passing through esophageal opening
Esophagus
Phrenic nerve
Vagus nerve
Gastric aery branches
1b
single
At T8 - IVC hiatus in central tendon through which IVC and few branches of Rt. phrenic nerve passes At T10 - Oesophageal opening is present through which passes: Esophagus Esophageal branch of left gastric aery Anterior and posterior vagal trunk At T12 - Aoic hiatus posterior to diaphragm formed by median arcuate ligam...
Anatomy
Umblicial cord and diaphragm
ff0c1890-3cb3-4860-bfc1-7271ee281380
Waist Hip Ratio in men that indicate obesity
> 0.85
> 0.95
> 1
> 1.5
2c
single
null
Social & Preventive Medicine
null
2d61b4b3-2e53-42c7-a522-664232329f13
Notching of the ribs is seen in man
TR
TOF
Coarctation of aoa
PDA
2c
single
Coarctation of aoa
Radiology
null
07d6a46a-d033-40a0-bfe1-c06f0d253580
Baezomib is -
Proteosome inhibitor
DNA methyl transferase inhibitor
Tyrosine kinase inhibitor
Histone deacylase inhibitor
0a
single
Ans. is 'a' i.e., Proteosome inhibitor Proteosome inhibitors o Transcription factor NFKB is associated by an inhibitor IKB. o IKB is degraded by proteosomes. o Inhibition of proteosome prevents degradation of IKB which inhibits the overactivity of NFKB. o Proteosome inhibitor (Baezomib) is used in multiple myeloma.
Pharmacology
null
092281c7-4644-497c-a202-e5931a5c01dd
Superior rib notching is/are caused by:
Hyperparathyroidism
Poliomyelitis
Marfan syndrome
All
3d
multi
A, B, C, i.e. Hyperparathyroidism, Poliomyelitis, Marfan syndome
Radiology
null
6bb1a391-2c8d-45aa-9f20-54b3d60248b5
Destruction of fat in acute pancreatitis is due to -
Lipase and elastase
Lipase and trypsin
Secretin
Cholecystokinin and trypsin
1b
single
An enzyme activated by trypsin is phospholipase A2. This enzyme splits a fatty acid off lecithin, forming lysolecithin. Lysolecithin damages cell membrane. It has been hypothesized that in acute pancreatitis phospholipase A2 is activated in the pancreatic ducts, with the formation of lysolecithin from lecithin that is ...
Pathology
null
133910cc-48fc-40c8-9278-6e8c19219f14
The very first step in investigation of Epidemic
Confirmation of existence of epidemic
Verification of diagnosis
Development of epidemiological case sheet
Formulation of Hypothyesis
1b
multi
INVESTIGATION OF AN EPIDEMIC The occurrence of an epidemic always signals some significant shift in the existing balance between the agent, host and environment. It calls for a prompt and thorough investigation of the cases to uncover the factor(s) responsible and to guide in advocating control measures to prevent fuhe...
Social & Preventive Medicine
Epidemiology
d82e30e4-1785-4853-b836-c10ec3c098c1
Orally administered anti kala-azar drug is
Paromomycin
Miltefosine
Amphotericin
Sodium stibogluconate
1b
multi
Ans. is 'b' i.e., Miltefosine o Drugs used for kala-azar :- o Parentral : Amphotericin-B (iv), Paromomycin (im), sodium stibogluconate (iv or im). Oral : Miltefosine
Pharmacology
null
7ff5e2d3-c3a2-4693-a8a7-131d1830dcab
Which DNA segments in the lactose operon of E. coli is a trans-acting regulatory element?
B-galactosidase gene
Operator
Promoter
I gene
3d
single
Regulatory sequences in DNA are classified as cis- or trans-acting elements, depending on the mechanism of action. Cis-acting elements function only when located on the strand of DNA being regulated, relatively close to the regulated gene. The operator (0), the promoter (P), and the CAP binding site all are located jus...
Biochemistry
All India exam
b377d5f1-5b0a-45ac-92c9-3fed3bc05958
Comment on the diagnosis for an individual serum alkaline phosphatase normal, PTH normal, Vitamin D3 normal with elevated serum Calcium values?
Vitamin D intoxication
Hyperparathyroidism
Multiple myeloma
Nutritional rickets
2c
single
Multiple myeloma is a plasma cell neoplasm commonly associated with lytic bone lesions, hypercalcemia, renal failure, and acquired immune abnormalities. Clinical Features. The clinical features of multiple myeloma stem from (1) the effects of plasma cell growth in tissues, paicularly the bones (2) the production of exc...
Pathology
FMGE 2019
3141aace-abf3-4584-9881-498b0ae1b400
"Gold standard" study for diagnosis of pulmonary embolic episode is:
Ventilation perfusion scan
Pulmonary angiography
Chest x-ray
Multi slice CT
1b
single
Ans. B. Pulmonary angiographyAlthough pulmonary angiography is supposed to be the definitive and gold standard means of diagnosing PULMONARY EMBOLISM with the decreasing availability of pulmonary arteriography and increasing use of other non-invasive tests like spiral CT, the exact role of pulmonary arteriography is no...
Radiology
Respiratory System
745a0b8a-1943-4076-8ec0-7494f0bf7666
Tryptophan is
Glucogenic
Ketogenic
Both glucogenic & ketogenic
None
2c
multi
During metabolism Tryptophan, pa of carbon skeleton enters ketogenic pathway and rest glucogenic pathway. Alanine is glucogenic and Acetoacetyl CoA is ketogenic.
Biochemistry
Metabolism of protein and amino acid
2e5b6018-c5f4-44d9-aa1f-fc73ee0696d6
A 3–month old male child with normal genitalia presents to the emergency department with severe dehydration, hyperkalemia and hyponatremia. The measurement blood levels of which of the following will be helpful?
17–hydroxy progesterone
Renin
Cortisol
Aldosterone
0a
single
This is a case of congenital adrenal hyperplasia due to deficiency of 21 - hydroxylase deficiency. Because of the enzyme block ,there is increased formation of 17- hydroxyprogesterone, which is then shunted into the production of testosterone. Levels of cortisol and aldosterone are reduced.
Pediatrics
null
e530722d-fd21-4026-8be6-d9fd20cabc84
Refeeding Syndrome - Lab values to be monitored are all except
Calcium
Magnesium
Phosphate
Ammonium
3d
multi
Ans. (d) AmmoniumRef: Bailey and Love 27th edition Page 288, Surgery Sixer 3rd Edition Page 6Refeeding Syndrome* Characterized by severe fluid and electrolyte shifts in malnourished patients undergoing refeeding.* It can occur with Enteral and Parenteral nutrition (MC with TPN)* Lab values: Hypophosphatemia, Hypocalcem...
Surgery
Fluid & Electrolyte
b65ca73f-bca9-45cc-9cb3-6a9934924ccb
Mucormycosis of paranasal sinus is most common in
HIV
Diabetes
Those on immuno suppressants
Post surgical
1b
single
MUCORMYCOSIS: Caused by - rhizopus , rhizomucor , cunninghamella Moulds with non septate hyphae The higher prevalence of mucormycosis in India turned out to be statistically significant (p < 0.0001) in comparison with all other countries Predisposing factors - Organ transplant recipients - Long term desferroxamine ther...
ENT
null
b0ea28b6-46e2-47dd-8bf5-7aa4091d565e
Spironolactone is most useful in _________ syndrome:
Zollinger-Ellison
Conn's syndrome
Cushing syndrome
Acromegaly
1b
single
null
Medicine
null
afc45b91-f055-4779-8c39-27391adec243
Which of the following supplies the pineal gland?
Posterior choroidal aeries
Tuberothalamic
Recurrent aery of Heubner
Lenticulostriate aery
0a
single
Pineal gland is present posterior to midbrain so if tumor is in pineal gland ,it may l/t dorsal mid brain syndrome as it would press on the midbrain from behind. * MCA(Middle Cerebral Aery) not a pa of Circle of Willis * PCA (Posterior Cerebral Aery) P1,P2 and 10-11 Post choroidal aeries P1 supplies- Midbrain P2 suppli...
Medicine
Raised ICP and Brain death
7174ef25-4244-496c-8a1e-5f9f21f6d9fd
A 54-year-old man is admitted to the hospital due to severe headaches. A CT examination reveals an internal carotid artery aneurysm inside the cavernous sinus. Which of the following nerves would be typically affected first?
Abducens nerve
Oculomotor nerve
Ophthalmic nerve
Maxillary nerve
0a
multi
The abducens nerve would be affected first due to aneurysmal dilation of the internal carotid artery (ICA) because the nerve runs in closest proximity to the artery within the cavernous sinus. The other nerves running in the wall of the cavernous sinus are the oculomotor nerve, trochlear nerve, and both the maxillary a...
Anatomy
Head & Neck
b0941911-2f3b-4e96-9e75-3adfb1156dc2
Coenzyme required for tissue respiration is
Coenzyme Q
Coenzyme A
NADP
Cobamide
0a
single
Coenzyme Q (CoQ) is a quinone derivative with a long, hydrophobic isoprenoid tail. It is also called ubiquinone because it is ubiquitous in biologic systems. CoQ is a mobile carrier and can accept hydrogen atoms both from FMNH2, produced on NADH dehydrogenase (Complex I) and from FADH2, produced on succinate dehydrogen...
Biochemistry
Respiratory chain
bc5c2bc1-45c2-4757-abfe-59516ddff076
Cause of death in Carcinoma penis is usually -
Metastasis to lung
Metastasis to liver
Erosion of Femoral blood vessels
Urinary obstruction
2c
multi
Inguinal lymph nodes erode the skin of the groin and the death of the patient may be due to involvement of the femoral or external iliac artery with torrential hemorrhage.
Surgery
null
91aef141-0a3a-4edc-bcbb-831ddb28bf27
All are true about levamisole EXCEPT:
Act as an immunostimulator
Act as an immunodepressor in high doses
Single dose is sufficient for the treatment of psoriasis
Acts antihelminthic by causing depolarization
2c
multi
Levamisole- Active against many nematodes, but use is restricted to ascariasis and ancylostomiasis because the action on other worms is poor. The ganglia in worms are stimulated causing tonic paralysis and expulsion of live worms. Interference with carbohydrate metabolism (inhibition of fumarate reductase)may also cont...
Pharmacology
Immunomodulators
cf5c8cac-b077-4d10-b662-2940279ea4ad
In patients with osteoahritis of knee joint, atrophy occurs most commonly in which muscle :
>Qudriceps only
>Hamstrings only
>Both (a) and (b)
>Gastrocnemius
0a
multi
Quadriceps only Met Maheshwari 3/e, p 253;Apley's 8/e, p 472] In osteoahritis of knee joint, the quadriceps muscle is usually wasted.
Surgery
null
139b56c6-0426-4e38-a5ec-adb5db133743
All of the following are pyrogenic cytokines, Except-
Interleuken 18 (IL-18)
Interleuken 6 (IL-6)
Tumor Necrosis Factor (TNF)
Interferon a (IFN-a)
0a
multi
Ans. is 'a' i.e., Interleukin 18 (IL-18) Interleukin 18 is not a pyrogenic cytokine.
Pathology
null
90249ff6-3e92-4577-bf75-2e6aab78f48b
All of the following are known causes of recurrent aboion, except:
TORCH infections
SLE
Rh incompatibility
Syphilis
0a
multi
SLE is associated with antiphospholipid syndrome (anti cardiolipin antibodies) and is known to cause recurrent aboions. RH incompatibility is a known cause for spontaneous aboion and may lead to recurrent aboions if it remains unrecognized. Syphilis has also lead to recurrent aboion. TORCH is thus the single best answe...
Gynaecology & Obstetrics
null
9ac5f543-88c9-4060-829d-b0f9c1012817
Pontaic, fever is caused by -
Legionella
Listeria
Scrub typhus
Leptospira
0a
single
Ans. is 'a' i.e., Legionella
Microbiology
null
f5a7bf26-0527-4fb8-a48b-8d715ee2c967
A patient presents with fever, cough with sputum and weight loss. He has a history of not completing treatment for tuberculosis thrice in the past. XDR-TB is suspected. How is XDR-Tb defined?
Resistant to INH + Rifampicin + Amikacin
Resistant to INH + Amikacin + Ofloxacin + Ethambutol
Resistant to INH + Rifampicin + Amikacin + Ofloxacin
Resistant to Rifampicin + Amikacin+ Ofloxacin
2c
single
XDR-TB (Extensively drug-resistant TB) is defined as MDR TB (Resistant to rifampicin and isoniazid) + Resistant to one fluoroquinolone (eg. ofloxacin) + resistance to one injectable second line drug (Amikacin or kanamycin or capreomycin). Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition
Microbiology
Bacteriology
bfdf4cf8-7ed4-44d6-86ae-aa909a3e25eb
False about acute aluminium phosphate poisoning:
Subendocardial infarct
Produce phosphine gas
Inhibit mitochondrial cytochrome oxidase
Oesophageal stricture
3d
multi
D i.e. Oesophageal stricture Aluminium (zinc) phosphide or celphos poisoning liberates phosphine gas which inhibits mitochondrial cytochrome oxidase, respiratory chain enzymes and electron transpo systemQ. It is a systemic poison and kills most of patients with in 24 hours secondry to cardiovascular collapse d/t direct...
Forensic Medicine
null
e716deb5-93cf-42d2-a97d-be2afebf4f64
The vertical fracture of root seen with gutta percha obturation is due to:
The vertical compression of warm GP points
Lateral condensation of GP points
Use of spreader
Injection molding technique
0a
single
null
Dental
null
ae34c60a-0334-4183-9d3d-e68fe9fe6bb0
Alzheimers disease, true is all except -
Anterograde amnesia
Dysdiadochokinesia
Receptive aphasia
Recognition of familiar faces is absent
1b
multi
null
Medicine
null
08da0a28-d8b8-438a-8842-708528ebacc0
Injury occurs at C7 root, in what pa of arm, sensation will be lost ?
Upper medial
Lower medial
Posterior
None of the above
3d
multi
Ans. is 'd' i.e., None of the above
Anatomy
null
c5e6adb2-792a-47e5-a514-bf0f6162785f
A child having delayed separaion of umbilical cord with leukocytosis with Downs syndrome and recurrent infections. Diagnosis ?
Leucocyte Adhesion deficiency
Neonatal sepsis
Histiocytosis-X
All of above
0a
multi
Leukocyte adhesion deficiency (LAD) is a rare primary immunodeficiency. The clinical picture is characterized by marked leukocytosis and localized bacterial infections that are difficult to detect until they have progressed to an extensive level secondary to lack of leukocyte recruitment at the site of infection. Thus ...
Pediatrics
Genetic and genetic disorders
c4d2eb68-49ae-4504-9d19-c60c9e46472f
False regarding Cytochrome P 450 is ?
They are essential for the production of cholesterols, steroids, prostacyclins and thromboxane A2
They absorb light with 45nm wavelength
They occur predominantly in liver
They are non heme proteins
3d
multi
Ans. is d i.e., They are non heme proteins CYTOCHROME P450 They CYP450 are essential for the production of cholesterols, steroids, prostacyclins and thromboxane A2. They are also essential for the metabolism of foreign chemicals and detoxification of drugs. CYP 450 enzymes are so named because they are bound to membran...
Pharmacology
null
598bcc45-6061-4552-9a61-5fc003255aa6
The mode of inheritance of Incontinentia pigmenti is -
Autosomal dominant
Autosomal recessive
X-linked dominant
X-linked recessive
2c
single
Ans- C X-linked dominant
Skin
Autoimmune Skin Disorders
bbbd4c9a-a388-4111-8a1f-f30c2a9b90b7
Ramu, presents with recurrent attacks of cholelithiasis, U/S examination shows a dilated CBD of 1 cm. The next line of management is ?
ERCP
PTC
Cholecystostomy
Intravenous cholangiogram
0a
single
Ans. is A ie. ERCP The first inv. for any pt. with cholelithiasis or jaundice is U/S. Next inv. depends on U/S findings, If the intrahepatic ducts are dilated without any extrahepatic dilatation then the preferred inv. is ----> PTC* If the dilatation is in CBD ---> ERCP*. ERCP may provide direct diagnosis of the distal...
Surgery
null
5a3bf5e9-5210-4a40-87e2-60bcbe1a2e2d
A 50 year old male patient came with the complaint of palpitations. Examination of pulse revealed irregular heabeat and advised ECG recording. Spread of cardiac impulse is fastest in which of the following structure
SA node
AV node
Bundle of His
Purkinje fibre
3d
single
Conduction speed in cardiac tissue: Tissue Conduction Rate SA node 0.05 Atrial pathways 1 AV node 0.05 Bundle of His 1 Purkinje system 4 Ventricular muscle 1 Purkinje fibers also have the ability of firing at a rate of 15-40 beats per minute if upstream conduction or pacemaking ability is compromised. In contrast, the ...
Physiology
Cardiovascular system
17ca54f6-b5fe-42da-8454-8cd4b093151f
Golgi tendon apparatus conveys message to CNS, depends upon:
Tension in muscle
Length of muscle
Rapidity of contraction
Blood supply
0a
single
Golgi tendon organs are in series with the muscle fibers, they are stimulated by both passive stretch and active contraction of the muscle, when  tension increases inside muscle.
Physiology
null
4c5bd805-c9a7-4d37-8220-514de5b2293c
Best stimuli for secretin is-
Protein
Acid
Fat
Bile
1b
single
B i.e. Acid
Physiology
null
75b6a53f-ad40-42f8-a090-e829166a4807
Drugs used in congestive hea failure are All except
Nesiritide
Digoxin
Spiranolactone
Adrenaline
3d
multi
As a medication, adrenaline is used to treat a number of conditions including anaphylaxis, cardiac arrest, and superficial bleeding. Inhaled adrenaline may be used to improve the symptoms of croup. It may also be used for asthma when other treatments are not effective. It is given intravenously, by injection into a mus...
Pharmacology
Cardiovascular system
fabfb7b9-67d8-41b5-962d-8c5a453408f4
All are transmitted by blood except -
Parvovirus B-19
Hepatitis G
Epstein Bar virus
Cytomegalovirus
2c
multi
Ans-CEpstein Barr Virus??? Viruses associated with blood transfusion:Hepatitis C virus:Hepatitis G virus:Hepatitis B virusHIV type IHTLV Type ICytomegalovirusParvovirus B-19HGVA recently discovered and identified non A-E hepatitis virus has been designated the name Hepatitis G virus (HGV) which is a member of Flaviviri...
Unknown
null
a5686bd1-7bae-432c-ab49-7fdb6b5dd353
An adult patient presents with leg pain. On examination there is gangrene of his toe. What would be the ankle to brachial aerial pressure ratio in this patient ?
1
0.3
0.5
0.8
1b
single
Since this patient has developed gangrene of the toe ankle to brachial presure ratio should be less than 0.3. Ratio of ankle to brachial systolic pressure (ankle brachial index) is obtained to determine the presence and magnitude of occlusive disease. The ankle brachial index of 0.9 - 1.0 indicates normalcy or minimal ...
Surgery
null
ec880431-82ce-4ae4-872d-5eb8081d2d2d
The infection that is spreading to the newborn by caregivers?
Candida albicans
Candia galbrata
Candida parapsilosis
Candida tropicans
2c
single
Ans is (c) i.e Candida Paraspilosis Ref Clin MicroHol Rev. Oct 2008: 21(4): 606-625 Candida parapsilosis is an emerging major human pathogen that has dramatically increased in significance and prevalence over the past 2 decades, such that C. parapsilosis is now the second leading causes of invasive candidal disease. In...
Microbiology
null
a694ce66-4884-4fdd-9534-e488006ea631
Hepatotoxic drugs are
Chloroform
Halothane
Both are above
None
2c
multi
Refer KDT 6/e p372 Massive liver necrosis following Halothane anaesthesia is seen in some cases If chloroform cos given for long period liver damage occurs
Pharmacology
Anesthesia
730e3927-c77f-4357-88f3-1ce4f87307fb
Which of the following statement is false regarding phenobarbitone: September 2011
Act primarily at the GABA: BZD receptor-Chloride ion channel complex
Crosses placenta
May precipitate porphyria
No significant interaction with warfarin
3d
multi
Ans. D: N significant interaction with warfarin Barbiturates stimulates hepatic microsomal catabolism of warfarin Phenobarbital/ Phenobarbitone It is a barbiturate It is the most widely used anticonvulsant worldwide, and the oldest still commonly used. The World Health Organization recommends its use as first-line for ...
Pharmacology
null
9d5ec875-763a-40b9-bb80-84ecebf800b1
Optic tract fibers project to the superior colliculi for
Reflex gazes
Light reflex
Generation of circadian rhythms
Veical nystagmus
0a
single
Optic tract fibers project to the superior colliculi for reflex gazesPretectal area for the light reflexSuprachiasmatic nucleus of the anterior hypothalamus for generation of circadian rhythms
Microbiology
All India exam
6e79c796-606a-4897-befe-e25bcd260b93
Traid of Bulgar urethral injury includes all except
Perimeal hematoma
Blood at external urethral meatus
Acute retention of urine
Pelvic hematoma
3d
multi
Pelvic hematoma occurs in membranous urethral injury not bulbar urethral injury.
Surgery
null
4271fa97-23ea-418a-a877-51c7a213b1b7
Which of the following deals with section 377, I.P.C?
Unnatural sex offences
Rape
Incest
Adultery
0a
single
Voluntary sexual intercourse against the order of nature with any man, woman, or animal is an unnatural sexual offence (Section 377 I.P.C). Penetration is sufficient to constitute the offence. These offences are punishable with imprisonment for life or upto ten years and also with fine. Ref: The Essentials of Forensic ...
Forensic Medicine
null
bcb88621-6e51-495d-b7ee-3b5decc1fd7e
A 60-year man had undergone cardiac bypass surgery 2 days back. Now he staed forgetting things and was not able to recall names and phone numbers of his relatives. What is the probable diagnosis?
Depression
Post-traumatic psychosis
Cognitive dysfunction
Alzheimer's disease
2c
multi
The history of cardiac surgery 2 days prior followed by behavioral changes is suggestive of delirium. The question here is stressing on "disturbances of memory" which can be seen in delirium, however are usually restricted to sho term memory loss. The other impoant features such as clouding of consciousness and attenti...
Psychiatry
Organic Mental Disorders
2646edf5-8673-4dbe-b0bf-4cdf36be73ff
Striatum damage affects priming
Procedural memory
Sho term memory
Long term memory
Explicit memory
0a
single
Implicit memory is subdivided into 4 types. Procedural memory includes skills and habits, which one acquired become unconscious and automatic. Priming is facilitation of recognition of words or objects by prior exposure to them. Ganong&;s review of medical physiology; 23rd edition; pg: 290
Physiology
Nervous system
18843a5c-d0aa-4479-be20-b31105595dc0
In facial palsy, food accumulated in the mouth due to paralysis of
Masseter
Temporalis
Mentalis
Buccinator
3d
single
(D) Buccinator > The facial nerve contributes to the oropharyngeal phase of deglutition via the buccinator, perioral, digastricus posterior, and stylohyoid muscles. The gustatory and salivatory functions of the facial nerve are also known to contribute to swallowing.> The relation between peripheral facial nerve palsy ...
Medicine
Miscellaneous
75486946-8808-41b9-b03e-9ed065ccb9d2
Glycogen phosphorylase coenzyme associated is?
Thiamine pyrophosphate
Tetrahydrofolate
Flavin mononuleotide
Pyridoxal phosphate
3d
single
ANSWER: (D) Pyridoxal phosphateREF: Lehninger Principles of Biochemistry 4th edition page 562Pyridoxal phosphate is an essential cofactor in the glycogen phosphorylase reaction; itsphosphate group acts as a general acid catalyst, promoting attack by Pi on the glycosidic bond. (This is an unusual role for this cofactor;...
Biochemistry
Glycogen Metabolism and Glycogen Storage
6decd79e-783c-41f9-92b7-e0b6e1528838
The minimum number of feeding days in a year recommended, under Mid-day meal programme is
200
250
300
350
1b
single
Recommended norms of 450 Kcal and 12 g protein for a minimum of 200 days Ref : Park 23rd edition Pgno :661
Social & Preventive Medicine
Health programmes in India
48e79fac-305f-4e93-bd07-958b7264b734
Most characteristic eye lesion in diabetes is
Papilledema
Proptosis
Capillary aneurysm
Cataract
2c
single
Most characteristic - Capillary aneurysm.
Ophthalmology
null
66e6d1a7-8e54-47b0-83f1-3d42e5503212
A 24-year-old female complains of suicidal ideation. She lost her family in a car accident earlier this year. Since then, she had problems with focusing on her work. She was laid off from her work as she was making many errors due to false judgment. She was rescued from suicidal attempts a couple of times. She was pres...
Thiopentone
Ketamine
Methohexital
Fentanyl
2c
multi
Answer: c) MethohexitalMethohexital has minimum interference with therapeutic induction of seizures. Hence, it is the drug of choice for electroconvulsive therapy (ECT).Propofol can be used as an alternative if methohexital is contraindicated.Therapeutic seizures induced by ECT typically last for 15-70s.The steps invol...
Psychiatry
Treatment
ceea01dd-8ff5-4a6b-8d8b-1b5e800491e2
40 yr old with koilonychias, iron deficiency & dysphagia, diagnosis is -
Plummer Vinson syndrome
Achalasia cardia
ZES
None
0a
multi
Ans. is 'a' i.e., Plummer Vinson syndrome Plummer-Vinson syndromeo Plummer-Vinson syndrome, also known as Brown-Kelly-Paterson syndrome or sederopenic dysphagia, seen in middle aged edentulous women.o The plummer Vinsion Paterson Brown Kelly Syndrome is characterized by: -DysphagiaChronic iron deficiency anemiaAtrophic...
ENT
Oesophagus
6264db2a-a94d-4806-a0d7-23cba0aeb0f7
The most common site of perforation in tympanic membrane is
Antero inferior
Postero inferior
Postero superior
Antero superior
0a
single
Perforations. They may be central, attic or marginal and are associated with chronic otitis media The most common site of Tympanic membrane perforation is antero-inferior quadrant. Ref : Diseases of ENT by Dhingra 6th edition Pgno : 56,71
ENT
Ear
b27f4464-a60d-442f-ae18-be672caa02e9
A carrier who gets infected from another carrier is known as:-
Incubatory carrier
Paradoxical carrier
Convalescent carrier
Pseudo carrier
1b
single
Paradoxical carrier - A person gets infected from another carrier and himself becomes Carrier. Carriers are of 6 major types: Content carrier - Carrier gets infection from a case Paradoxical carrier - Carrier gets infection from another carrier Chronic carrier - Carrier for duration of more than 6 months Incubatory car...
Social & Preventive Medicine
Other Key Definitions & Concepts
0d491b97-af0c-41f5-9ff9-caed29402111
Which is the treatment of choice for CA head of pancreas
Radiotherapy
Chemotherapy+ Radiotherapy
Whipple's Surgery
Resection of the entire pancreas with adjuvant chemotherapy
2c
single
Answer- C. Whipple's SurgeryWhipples operation (Pancreaticoduodenectomy) is the most commonly performed operation for carcinoma of head of Pancreas.
Surgery
null
27113652-c797-4f8d-b351-66994a754993
Kartagener's syndrome increase risk of -
Brochitis
Bronchiolitis
Brochieactasis
Tracheitis
2c
single
Ans. is 'c' i.e., Bronchieactasis
Pathology
Respiration
b58e17c9-2829-4884-8708-e7c1b762dc20
An accused in a case of sodomy is brought for Medical Examination. On detailed questioning, he reveals that he is an active agent and is a regular participant. Which of the following will not be seen during the examination of the accused -
Presence of smegma
Fecal smell
Tear of Frenulum
Relative constriction of shaft of penis
0a
single
Presence of thick uniform coating of smegma under prepuce and around corona glandis is suggestive of absence of inter course (vaginal or anal) within the last 24 hours since it gets rubbed off during the sexual act. However, its an unreliable sign with no medicolegal value as its presence or absence depends on personal...
Forensic Medicine
null
df13d382-364f-440a-82f1-c14fb4f02a4b
30 yea raid female comes with acute breathelessness, neck vein distension, absent breath sounds and mediastinal shift. Which of the following should be done immediately: (PGI June 2008)
HRCT Ls the investigation of choice
ABG analysis should be done
CXR
Large bore needle puncture of pleura
3d
single
Ans.: D {Large bore needls puncture of thorax) (Ref Harrison 17th/1660; Oxford Textbook of Surgery'/1932}The young lady from the case history is suffering from tension pneumothorax.The immediate management of such patient should be large bore neelds punctureQ of thorax through second anterior intercostals space to save...
Medicine
Pulmonary Diagnostic Procedures
ab205150-9ee8-4714-9c4d-a04034af704d
All are true statements about Conversion disorder except
Autonomic nervous system involved
There is primary and secondary gain
La bella indifference is a feature
Patient does not intentionally produce symptoms
0a
multi
Conversion Disorder Conversion disorder is characterised by the following clinical features: 1. Presence of symptoms or deficits affecting motor or sensory function, suggesting a medical or neurological disorder. 2. Sudden onset. 3. Development of symptoms usually in the presence of a significant psychosocial stressor(...
Psychiatry
Somatoform disorders
dda71056-4f4e-4390-9441-65fb030682bb
HLA gene for abacavir hypersensitivity is?
B5
B51
DQ2
B57
3d
single
Drug allergies are the most significant allergic reactions occurring in HIV-infected patients and appear to become more common as the disease progresses. Anaphylaxis is extremely rare in patients with HIV infection, and patients who have a cutaneous reaction during a single course of therapy can still be considered can...
Medicine
Immune system
43d4126c-e798-40cb-8380-1bfb87095fe2
Major Pyrogenic cytokine:
INF alpha
TNF beta
IL-3
IL-1
3d
single
Ans. D. IL-1. (Ref Robbins Basic Pathology 8th/ Table 2-6).IL-1: fever.IL-2: stimulates T cells.IL-3: stimulates bone marrow.IL-4: stimulates IgE production.IL-5: stimulates IgA production.IL-6: stimulates acute-phase protein production.IL-8: recruites Neutrophils. Tumor Necrosis Factor and Interleukin-1# TNF and IL-1 ...
Pathology
Cellular Pathology