id
stringlengths
36
36
question
stringlengths
1
1.57k
opa
stringlengths
1
287
opb
stringlengths
1
287
opc
stringlengths
1
286
opd
stringlengths
1
301
cop
class label
4 classes
choice_type
stringclasses
2 values
exp
stringlengths
1
22.5k
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
0daffc3e-eb67-4a55-bb29-481fa7dc17ec
Mucocelr is commonly seen in sinus:
Frontal
Maxillary
Ethmoid
Sphenoid
0a
single
A mucocele is an epithelial lined,mucus containing sac completely filling the sinus and capable of expansion: Mucocele are most commonly formed in frontal sinus followed by Ethmoid,sphenoid and maxillary sinuses. Mucocele of frontal sinus presents as a swelking in the floor of frontal sinus above the inner canthus.Itbd...
ENT
Nose and paranasal sinuses
3d881fde-4a5a-4515-ab42-5ac796910ca9
Investigation of choice for Entrapment Neuropathy is?
CT
MRI
Clinical exam
SPECT
1b
single
ANSWER: (B) MRIREF: Surgical management of pain by Kim Burchiel Page 658, Neurology by Jon Brillman 8f Scott Khan page 110EMG and nerve conduction studies are done to identity the site of entrapment. Imaging is done to rule out any occult fracture and MRI for visualization of entrapped nerve in the tunnel. MRI is the i...
Radiology
Brain Imaging: Anatomy, Trauma, and Tumors
c60a5450-bafb-45ff-a9c7-c556fdb91c13
Graham Cole test refers to
Oral cholecystography
Intravenous cholangiography
Pre operative cholangiography
Post operative cholangiography
0a
single
Oral cholecystography (Graham Cole Test) Once considered the diagnostic test of choice for gallstones, oral cholecystography has been replaced by ultrasonography It involves oral administration of a Radiopaque compound that is absorbed, excreted by the liver, and passed into the gallbladder Successful visualisation of ...
Anatomy
G.I.T
7013a79a-27e8-41e3-905e-3029db80aed1
Node of Ranvier is seen in -
Cell body
Dendrites
Axons
Terminalbutons
2c
single
Ans. is 'c' i.e., Axons o Nodes of Ranvier are periodic gaps in the myelin sheath on the axon.o Neuron is the functional unit (basic unit of nervous tissue).o It is specialized for the function of reception, integration and transmission of information in the body,o The basic structure of neuron is best studied in a spi...
Physiology
Nerve Physiology
b639153c-1ec5-444d-b310-fcf57350eef4
Parasympathetic stimulation of nerves innervating the islets of the pancreas will:
Have no effect
Increase secretion of insulin from B cells
Decrease secretion of insulin from B cells
Increase secretion of glucagon from B cells
1b
single
The pancreatic islets receive innervation from both the sympathetic and parasympathetic nervous system. Stimulation of the parasympathetic system increases secretion of insulin from the B cells. Stimulation of the sympathetic system increases glucagon secretion from the A cells. Insulin is inhibited by sympathetic stim...
Physiology
null
67a82175-4d94-4da5-bc9c-f7f9e912a5eb
A 25 yr old man presents for a routine examination The patient is tall and on examination was found to have an early diastolic murmur Family pedigree given what is the mode of inheritance of the disease in this patient
AD
AR
XLD
XLR
0a
multi
HISTORY SUGGESTIVE OF MARFANS SYNDROME . WHICH IS AD. REF : ROBBINS 10TH ED
Pathology
All India exam
cf44c8de-f1e9-458a-ba21-bad5587dda95
Rhinophyma is a slow growing tumour with the following pathology:
Hyperophy of the sebaceous glands
Hyperophy of sweat glands
Hyperplasia of endothelial cells
Hyperplasia of epithelial cells
0a
single
Rhinophyma or potato tumour is a slow growing benign tumour due to hyperophy of the sebaceous glands of the tip of nose.
ENT
null
1bfbb88b-7019-4a30-abdb-9127c9e177d8
Best indicator of protein quality:-
DIAAS
Amino acid score
PDCAAS
Protein efficiency ratio
0a
single
Best indicator of protein quality: DIAAS (Digestible indispensable amino acid scores) > PDCAAS (Protein digestibility-corrected amino acid score) >NPU (Net protein utilization). DIAAS =100 x . NPU = 100 x (Nitrogen retained by the body) / (Nitrogen intake) Other indicators: Amino acid score, Biological value, Protein e...
Social & Preventive Medicine
Proteins, Fats, Rich Sources
98c9b278-c141-4761-89ed-cc76e264d488
Amniocentesis for aneuploidy detection is best done at:
10-11 weeks
12-13 weeks
16-18 weeks
20-26 weeks
2c
single
AMNIOCENTESIS Amniocentesis is the most commonly performed procedure used to diagnose fetal aneuploidy and other genetic conditions. Indications Diagnosis of fetal genetic disorders Congenital infections Alloimmunization Assessment of fetal lung maturity Therapeutic for polyhydramnios The most common types of prenatal ...
Gynaecology & Obstetrics
Aboions, Spontaneous & Induced Emergency Contraception (Hey,whats the hurry !)
3e1d3db7-0b85-4f99-b51e-e136d4653999
What is the treatment modality for the following fracture?
Tension band wiring
External fixation
Plating
ORIF
0a
single
Image shows patellar fracture. Tension band wiring is also used for: Patellar fracture Olecranon fracture Medial malleolus fracture Tension band wire are loop of wires passed around two bony fragments and then tightened to compress the fragments together. External fixation is done by using screws and is applicable to t...
Orthopaedics
Fracture Management
59582804-4d98-4607-a458-87df0ece4bd9
Which of the following is true for Klinefilter's syndrome?
45 XO
Tall stature
Intelligent Quotient Normal
Normal testis and genitalia
1b
multi
Klinefelter syndrome Rare disorder, Karyotype 47 XXY, Externally resembles a male in general body conformity, Penis small or normal, Testes small, Gynaecomastia, Appearance eunuchoid, Mentally retarded, Azoospermia,Infeility, Tall stature, Testosterone may help in Rx Breasts may need surgical excision.
Gynaecology & Obstetrics
Mullerian Abnormalities
82921af6-9ed4-47e9-a630-8776ff400405
Isovolumetric relaxation ends immediately after
AV Valve doses
When ventricular pressure falls below aortic pressure
When ventricular pressure falls below atrial pressure
None of the above
2c
multi
null
Physiology
null
2c6d0837-72f1-4dad-ab58-0ff17f3c37f2
Endometrial cancer involving 50% of endometrium, extending to vagina, lymph nodes negative with positive peritoneal cytology is staged as
3a
3b
3c1
3c2
1b
single
3b FIGO STAGING OF ENDOMETRIAL CANCER STAGE I Cancer confined to corpus uteri IA --> Limited to endometrium IB --> < 1/2 myometrial thickness IC > 1/2 myometrial thickness STAGE II Tumour involves cervix but does not extend beyond uterus (la --> Cervical glandular involvement llb --> Cervical stromal involvement STAGE ...
Gynaecology & Obstetrics
null
d037a4fa-2923-473c-b4af-b0a545a54a14
Mucopolysaccharide having anticoagulant action is?
Heparin
Phenindione
Rivoroxaban
Dabigatran
0a
single
Ans. is 'a' i.e., Heparin Heparin It is a parenteral indirect thrombin inhibitor. It is a on uniform mixture of straight chain polysaccharides with molecular weight 10, 000 - 20, 000. It contains polymers of two sulfated disaccharide units D glucosamine L iduronic acid and D glucosamine D glucuronic acid. Heparin is th...
Pharmacology
null
68b6d0a0-2395-41ec-b10c-60812848b1b6
Patients suffering from multidrug resistant tuberculosis can be treated with all the following drugs EXCEPT:
Tobramycin
Amikacin
Ciprofloxacin
Clarithromycin
0a
multi
Multidrug-resistant (MDR) TB: is defined as resistance to both H and R and may be any number of other(1ST LINE) anti-TB drugs. MDR-TB has a more rapid course (some die in 4-16 weeks). Treatment of these cases is difficult, because one or more second line drugs are to be given for 12-24 months. If sensitivity of the TB ...
Pharmacology
Chemotherapy
e901d5c6-681d-48a1-9d47-2e443af8b175
A 19 year old boy fell from the motorbike on his shoulder. The doctor diagnosed him as a case of Erb's paralysis. All of the following signs and symptoms will be observed in this boy, EXCEPT:
Loss of abduction at shoulder joint
Loss of lateral rotation
Loss of pronation at radioulnar joint
Loss of flexion at elbow joint.
2c
multi
Due to Erb's paralysis there is damage of biceps brachii and supinator due to which there is loss of pronation of forearm. It is associated with loss of abduction at shoulder joint, loss of lateral rotation and loss of flexion at elbow joint and is not associated with loss of pronation at radioulnar joint.Erb's paralys...
Anatomy
null
59323b9a-1f31-42be-93d8-6b292c15a12b
Cut off duration for diagnosis of Priaspism is:
1 hour
2 hours
3 hours
4 hours
3d
single
Priapism: It is defined as a persistent painful erection lasting longer than 4 hours irrespective of any sexual stimulation & beyond reaching of orgasm. It is an emergency situation It is of two types: Ischemic priapism Non-ischemic priapism
Surgery
Urethra and penis
8c19ab09-5f86-42b9-9fa8-58a0cdb55f4f
Most common cause of biliary stricture is:-
CBD stone
Trauma
Asiatic cholangitis
Congenital
1b
single
MC cause of benign biliary stricture is laparoscopic cholecystectomy (operative trauma).
Surgery
Bile duct
e9dd2630-f4e8-4b77-b2d2-5f4ec769e9ee
A patient gives history of recurrent episodes of pain and swelling in Mandibular posterior region.He is diagnosed to have pericoronitis.The partially erupted 3rd molar was vital.On radiographical examination a well defined radiolucency was found with distal aspect of the respected tooth. What could be the daignosis:
Dentigerous cyst.
Paradental cyst.
Eruption cyst.
Periapical cyst.
1b
multi
Paradental Cyst Aka: Baccal bifurcation Cyst Craig’s cyst Collateral cyst Mandi 3rd molar – Association. Associated with VITAL TOOTH and recurrent pericoronitis DISTAL Aspect of mandi 3rd molar
Pathology
null
dfdd0c26-e619-4340-a1b6-806b0101fe35
Warm antibody in autoimmune hemolytic anemia
IgM
IgG
IgE
IgA
1b
single
Warm antibody is IgG.
Medicine
null
1ef10f1f-2c16-44cf-8493-0c845033795d
A 35-year-old coal worker presents with difficulty in breathing on exeion for last 2 years. CXR was performed. What does it show?
Emphysema
Reticulonodular infiltrates
Pulmonary fibrosis
Cardiac atrophy
0a
single
The CXR of Coal worker patient shows the presence of hyperinflation in lungs with a tubular appearance of the hea. Lungs appear relatively blacker with flattening of the diaphragm on both sides. The hea appears smaller as lungs are hyper-inflated. These findings are suggestive of emphysema.
Medicine
Interstitial Lung Disease
0add4cae-029a-43d2-96a2-fa23d821347d
Which of the following is not a direct route for transmission of communicable diseases?
Skin contact
Vertical
Droplet nuclei
Soil contact
2c
single
Ref. Foundations of Community medicine. Page. 393
Unknown
null
c805aedd-61ae-428f-96b4-9091eeed10cf
Which is not associated with diabetes mellitus?
Cushing syndrome
Acromegaly
Hypothyroidism
Phaeochromocytoma
2c
single
Coisol, growth hormone and catecholamines increase the blood sugar levels leading to impaired glucose tolerance or diabetes mellitus. whereas hypothyroidism is not associated with the blood sugar levels or diabetes mellitus
Medicine
Diabetes Mellitus
c2a87175-6a21-4a8a-aab4-228331f1ac63
Which of the following anaesthetic agents causes a rise in the Intracranial pressure –
Sevoflurane
Thiopentone sodium
Lignocaine
Propofol
0a
single
All inhalational agents increase ICT. Amongst intravenous agents only ketamine increases ICT. Propofol, etomidate, and barbiturates (thiopentone, methexitone) decrease ICT. Lidocaine decreases ICT.
Anaesthesia
null
f5a55dad-9c8f-4258-9946-431f3a9e5800
A study is looking at breast cancer of women compared cases with non-cases, and found that 75/100 cases used calcium supplements compared with 25/100 of the non-cases. Calculate Cross product ratio
9
6
3
12
0a
single
Odds ratio = ad/bc Breast cancer cases Non-cases Used Ca supplements 75 (a) 25 (b) Did not use Ca supplements 25 (c) 75 (d) 100 100 Odds ratio = ad/bc = 75*75/25*25 = 9
Social & Preventive Medicine
Case Control Study, Combined Designs
8a34a026-61b2-4841-bbf9-60ce44dbc637
Oculomotor nerve palsy show all of the following except -
Ptosis
Inability of lateral gaze
Paralysis of accommodation
Upward gaze not possible
1b
multi
Ans. is 'b' i.e., Inability of lateral gaze Features of 3rd (occulomotor) nerve palsy* Paralysis of superior rectus, inferior rectus, medial rectus and inferior oblique. Eye is down and out due to unopposed action of superior oblique and lateral rectus. Medial 8c upward gaze is not possible.* Paralysis of sphinctor pup...
Ophthalmology
Neuro-Ophthalmology
80b3c9e4-4cbd-46fe-84bd-f8c30d42fe5f
True about tropomysin is?
Lies on top of troponin
Lies on top of actin
ATP binds to it
Calcium binds to it
1b
multi
ANSWER: (B) Lies on top of actinREF: Guyton 12th ed page 72-76SLIDING FILAMENT THEORY OF MUSCLE CONTRACTION:In resting muscle, the ends of the actin filaments extending from two successive Z discs barely begin to overlap one another. Troponin I is tightly bound to actin and tropomyosin covers the sites where myosin hea...
Physiology
Skeletal Muscle: Contraction and Excitation
cee6e5ca-4a68-48a6-bba4-cc627de60e54
A male neonate is born with an omphalocele. This entity can be distinguished from gastroschisis, because in an omphalocele, the protrusion is:
Not covered by a sac
A defect in the abdominal musculature
Associated with Intestinal atresia
Associated with congenital malformations
3d
single
Abdominal wall defects Omphalocele- Intestine fails return to the intra-abdominal cavity- Covered by 2 layers* Amnion* Peritoneum- For Small defect - Protrusion of small amounts of bowel- For Large defect - Protrusion of small bowel along with liver- Associated with Trisomy 13, 18, 21- Associated with congenital malfor...
Surgery
Hernia and abdominal wall
f71e0a3f-66d0-4a4c-8f37-9fa25c7b8f2e
Following grows in the cell free medium except -a) Rickettsiab) M lepraec) Bartonellad) Syphilis
acd
abd
abc
ab
1b
multi
Obligate intracellular organisms To grow in a medium which does not contain cells (cell free medium), organism should be capable of ATP synthesis. Obligate intracellular organisms are not capable of the metabolic pathways for ATP synthesis. So, these organisms are dependent on the ATP of host cells. As they require...
Microbiology
null
be321bac-8de5-4f38-a7a3-00dff7519a26
Stage X3B refers to the following in the classification of vitamin A deficiency:
Night blindness
Corneal xerosis
Conjunctival xerosis
Keratomalacia
3d
single
d. Keratomalacia(Ref: Nelson's 20/e p 3 IB-320, Ghai B/e p 111-112)WHO classification of Vitamin A deficiency:IndicatorCategoryNight blindnessXNConjunctival xerosisX1ABitot's spotsX1BCorneal xerosisX2Corneal ulcerationX3AKeratomalaciaX3BXerophthalmia-related corneal scarsXS
Pediatrics
Nutrition
5e2f71c2-ac05-4d30-a114-d3d9049736ae
Clue cell is seen in aEUR'
Bacterial vaginosis
Candidial vaginosis
Chlamydiasis
Trichomonas
0a
single
Bacterial vaginosis Clue cells are seen in bacterial vaginosis -Clue cells are vaginal epithelial cells coated with coccobacillary organisms which have granular appearance and indistinct borders, on a wet mount prepared by mixing vaginal secretions with normal saline in a ratio of -1:1. Amsel criteria for the diagnosis...
Gynaecology & Obstetrics
null
b28001b1-1308-464d-a018-ba0b9dd88ef6
Gold standard test for diagnosis of laryngopharyngeal reflux is -
24 hr double probe pH monitoring
Flexible endoscope
Barium swallow
Laryngoscopy
0a
multi
null
ENT
null
6d73097d-03e6-47ab-85cf-0712d90bde54
When ICF and ECF of child becomes equal to adult person -
1 year
2 year
3 year
4 year
0a
single
Ans. is 'a' i.e., 1 year o In fetus, ECF is much larger than ICF. o By the age of 1 year, ratio of ICF to the ECF volume approaches adult level.
Pediatrics
null
d758ee59-0ada-4e65-a3b8-6f4042e863eb
Which of the following antimalarial agents is most commonly associated with acute hemolytic reaction in patients with glucose–6–phosphate dehydrogenase deficiency
Chloroquine
Clindamycin
Mefloquine
Primaquine
3d
single
null
Pharmacology
null
68afe46d-ff6c-4136-a9e1-5fc548ee19e8
The most important function of the microcirculation is:
The exchange of nutrients and wastes between blood and tissue
The filtration of water through capillaries
The regulation of vascular resistance
The autoregulation of blood flow
0a
single
Ans. A. The exchange of nutrients and wastes between blood and tissueEach of the choices is a function of the microcirculation, but its most important function by far is to provide tissue with nutrients and remove the wastes.
Physiology
Heart, Circulation, and Blood
ee6a612d-ef0d-49b4-86c8-48325f11f9ac
Altitudnal Field Defects are seen in
Non Aeritic Ischemic Optic Neuropathy
Lateral Geniculate Body lesions
Optic nerve lesion
Optic Chiasma Lesion
0a
single
Non aeritic AION Impoant Points on Visual Pathway Lesions 1. Optic nerve lesion I/l direct and c/ L consensual reflex gone Causes *Optic atrophy/ optic neuritis, Avulsion optic nerve 2. Middle Chiasmal syndrome/ Central Chiasmal lesion Saggital chiasma lesion Bitemporal hemianopia
Ophthalmology
Squint
89c14dd8-52cb-4533-b5a3-84860c168358
What is the treatment for headache in a case of peptic ulcer disease?
Microline aspirin
Propoxyphene
Paracetamol
Oxyphenbutazone
1b
single
Propoxyphene binds primarily to opioid receptors and produces analgesia and other CNS effects that are similar to those seen with morphine-like opioids. It is likely that at equianalgesic doses the incidence of side effects such as nausea, anorexia, constipation, abdominal pain, and drowsiness are similar to those of c...
Pharmacology
null
b684b1f4-5d5b-411e-8b4e-270617392fc3
Which of the following is not estrogen dependant carcinoma
Lobular carcinoma breast
Follicular thyroid carcinoma
Endomtrial leiomyosarcoma
Carcinoma prostrate
1b
single
Refer Robbins page no 1095
Anatomy
Endocrinology
c5c91064-b830-4133-b6b6-dc57f601518d
Vogt Koyanagi - Harada (VKH) syndrome is -
Chronic granulomatous uveitis
Chronic non-granulomatous uveitis
Acute purulent uveitis
None
0a
multi
(Ref: Khurana 7th/e p.175 & 4th/e p.156) VKH syndrome is a multisystem disorder characterized by chronic granulomatous uveitsi with exudative retinal detachment that is often associated with neurological and cutaneous manifestations.
Anatomy
General anatomy
549d744a-40a6-48ae-93ca-81086f758eb1
Gallstones do not contain:
Oxalate
Cholesterol
Phosphate
Carbonate
0a
multi
Gallstones In the USA and Europe, 80% are cholesterol or mixed stones, whereas in Asia, 80% are pigment stones Cholesterol or mixed stones - 51-99% pure cholesterol Pigment stone contains <30% cholesterol Black stones - Insoluble bilirubin polymer + calcium phosphate + calcium bicarbonate Brown pigment stones- calcium ...
Surgery
Gallbladder
5a72298e-2c2b-4d6b-8567-8ceab4759835
Typical CECT finding to suggest the diagnosis of pseudomyxoma peritonei is:
Scalloping of the visceral surfaces of the liver and spleen
Ascites with increased HU units
Peritoneal seedlings
Pseudokidney sign
0a
multi
CT-scan findings may be pathognomonic for pseudomyxoma peritonei, Typical CT appearance 1. Areas of low attenuation, with islands of higher attenuation due to solid elements within mucinous material. 2. Classically scalloping of visceral surfaces, paicularly of the liver and spleen Ref: World J Gastrointest Oncol 2010 ...
Surgery
null
ebcfc2c0-c32a-4f15-9602-644c6eeaacc4
Pathologic migration of tooth occurs:
Towards the bone resorption area
Always from the bone resorption area
Inciso occlusal direction
Axio inclined direction
0a
single
null
Dental
null
be839723-e30c-45d8-abe9-bb25d6038d5b
Which is the most likely cause of protein - losing enteropathy
Menetrier's disease
Monosaccharidase deficiency
Sarcoidosis
Celiac sprue
0a
single
null
Medicine
null
5247f4f5-c472-4950-b5ef-9cd9fc4b0001
The given ECG shows
Hypertrophic cardiomyopathy
Pulmonary embolism
Pericardial effusion
Anterior wall MI
1b
multi
Ans. B. Pulmonary embolism* The given ECG shows changes corresponding with pulmonary embolism.* Changes are- Sinus tachycardia- S1Q3T3 pattern (T-wave inversion in III)- Incomplete RBBB- Right precordial T-wave inversions* Consistent with acute RV overload in a patient with pulmonary emboli
Medicine
C.V.S.
439a1759-2aae-44f1-afa9-123e2c0e02fc
Which of the following is not an effect of cholinergic muscarinic receptor stimulation:
Sweating.
Bradycardia.
Urination.
Rise in BP.
3d
single
Stimulation of muscarinic receptors decreases BP.
Pharmacology
null
d4c93a77-b1b7-4503-af29-edbdcd49c219
Branched chain aminoacid is used in:
MODS
SIRS
Sepsis
Isolated hepatic failure
3d
single
Ans: d (Isolated hepatic failure)Ref: Various internet sitesBranched chain amino acids are used in hepatic encephalopathy to improve mental function and muscle control.They have been tried in burns, sepsis and trauma but without much success.Eg of branched chain amino acid -valine, leucine and isoleucine.
Pharmacology
Miscellaneous (Pharmacology)
0efb3ec6-3959-4d9c-a145-63be996607d1
All are true about in pubey menorrhagia Except:
Associated with anovulatory bleeding
Endometrial biopsy confirms diagnosis
Routine screening for bleeding disorder is done
Hematinics & Hormone therapy is the treatment of choice
1b
multi
Endometrial biopsy confirms diagnosis REF: Novak's gynecology 13' edition - page 152 Causes of mennorhagia in adoloscese Anovulatory bleeding Pregnancy-related Bleeding Exogenous Hormones Hematologic Abnormalities Infections Anatomic Causes Obstructive or paially obstructive genital anomalies typically present during a...
Gynaecology & Obstetrics
null
344703fa-32d7-4519-b85a-d0d3eba46ca0
'Murphy sign' is associated with: March 2004
Acute cholecystitis
Pancreatic mass
Splenomegaly
Carcinoma colon
0a
single
Ans. A i.e. Acute cholecystitis
Radiology
null
5b9a54d1-3de1-4250-b94a-10dd51eafe74
Schneiderian First rank symptoms are found in :
Schizophrenia
Organic delusional disorder
Schizoaffective disorder
All
3d
multi
A >> B, C The presence of one of these Schneider's first rank symptoms (SFRS) in the absenc of intoxication, brain injury or clear affective illness, was sometimes taken as sufficient for making diagnosis of schizophrenia (Kaplan). SFRS are not specifc for schizophrenia and may be seen in other psychiatric disorders su...
Psychiatry
null
b03c7bb7-6004-47e3-9302-52a8f0a6cf3b
A drug not effective in Multiple Myeloma is?
Boezomib
Hydroxyurea
Melphalan
Cylcophosphamide
1b
single
Hydroxyurea REF: Harrison 17th ed chapter 106 Drugs used in chemotherapy of multiple myeloma are: Melphan Thalidomide Lenalidomide Cyclophosphamide Vincristine Doxorubicin (Adriamycin) and liposomal doxorubici
Surgery
null
275d5c0f-685a-4098-b759-db64d7510d59
Which of following is true about allodynia?
Hyperalgesia
Loss of sensory sensations
Perception of non painful stimulus as pain
Hyperaesthesia
2c
multi
*Allodynia describes the situation in which a non painful stimulus ,once perceived ,is experienced as painful ,even excruciating . Allodynia refers to central pain sensitization (increased response of neurons) following normally non-painful, often repetitive, stimulation. Allodynia can lead to the triggering of a pain ...
Medicine
C.N.S
c5f14096-b705-43e2-b029-f80f6d9a262e
In pseudomyxoma peritonei, mucinous cyst-adenocarcinoma of which following organ is involved:
Pancreas
Kidney
Ovary
Abdominal testis
2c
single
Pseudomyxoma Peritonei Mucinous ascites Caused by ruptured Appendiceal or Ovarian Adenocarcinoma MC primary cause - Appendix > ovary Incidence- male = female Usually seen in 4th - 5th decade Peritoneal cavity is filled with mucinous substances (JELLY like) creates pressure in abdomen compressing the bowel & simultaneou...
Surgery
GIT
9d9d74fc-8449-4ab2-bbea-31d5781e5d60
Low serum haptoglobin in hemolysis is masked by ?
Pregnancy
Liver disease
Bile duct obstruction
Malnutrition
2c
single
Ans. is 'c' i.e., Bile duct obstruction Haptoglobin o Haptoglobin is a transpo glycoprotein which binds free hemoglobin in plasma and carries it to the reticuloendothelial system. It is synthesized in the liver. o A decrease in haptoglobin levels (with normal liver function) occurs when there is excess of hemoglobin in...
Pathology
null
bc477ab5-e4b4-495b-a396-285e3ac5dbc4
Disinfection frees the surface from
Vegetative forms
Spore forms
Both of the above
None of the above
0a
multi
null
Microbiology
null
a7e6a125-1209-4d86-9f15-5fd0b74ae44e
Right axis detion is seen In all except-
Ostium primum ASD
Dextrocardia
Pulmonary hypeension
Ostium secundum ASD
0a
multi
Right axis detion also may occur as a normal variant (paicularly in children and young adults), as a spurious finding due to reversal of the left and right arm electrodes, or in conditions such as right ventricular overload (acute or chronic), infarction of the lateral wall of the left ventricle, dextrocardia, left pne...
Medicine
C.V.S
c2ffd06f-c09b-465b-8f9a-6393b00c0f8e
Antral puncture is done through
Superior meatus
Inferior meatus
Middle meatus
All
1b
multi
Antral puncture and irrigation: Sinus cavity is irrigated with a cannula passed through the inferior meatus. Removal of pus and exudates helps the sinus mucosa to reve to normal. Ref: Dhingra 7e pg 219.
ENT
Diagnostic and operative ENT
e6ac5271-14bf-4399-aa45-b758ed27a955
Investigation of choice in whole body imaging in metastasis is -
Magnetic Resonance Imaging
Radiography
Bone scan
CT Scan
2c
single
Best investigation for bony metastasis is MRI. MRI has almost 100% sensitivity in detecting bony metastasis Investigation of choice for whole body screening for bony metastasis is Bone scan Intial investigation in symptomatic bone pain is Radiography CT is used in evaluation of focal abnormalities of bone scan and also...
Radiology
Skeletal system
604634a0-a333-4c54-8fb1-1da9616120c3
Treatment for achlasia associated with high rate of recurrence :
Pneumatic dilatation
Laproscopic myotomy
Open surgical myotomy
Botulinum toxin
3d
single
Ans. is 'd' i.e., Botulinum toxin Treatment of Achalasia The aim of treatment is to be relieve the functional obstruction at the cardia The two main methods to achieve this are I) Forceful dilatation or 2) Esophageal myotomy (Heller's myotomy) with or without an antireflux procedure 1) Forceful dilatation (pneumatic di...
Surgery
null
923d402b-94b8-46ef-b46a-9db913133da9
True regarding presentation of primary T.B. is -
B/L pleural effusion with negative Tuberculin test.
U/L hilar lymphadenopathy
Sustained chronic pyrexia
B/L pelural effusion with positive tuberculin test.
1b
multi
null
Medicine
null
ba45eb6a-052d-4e23-af45-7a0ae683be56
Most potent stimulus for secretin secretion is
Distension of stomach
Bile in duodenum
Protein in duodenum
Fatty food in duodenum
2c
single
Protein / acid in duodenum is the most potent stimulus for secretion of secretin.
Physiology
null
7661d34d-3cf7-4848-9c07-211e5460e3ff
Standard treatment of whole-brain radiotherapy (WB) for brain Metastasis :
20 grays (Gy) in 10 fractions
30 grays (Gy) in 10 fractions
30 grays (Gy) in 5 fractions
15 grays (Gy) in 10 fractions
1b
single
Ans. B, 30 grays (Gy) in 10 fractionsWhole-brain radiotherapy (WB) to 30 grays (Gy) in 10 fractions - Standard treatment in patients with multiple brain metastases.Current study investigated the potential benefit of dose escalation beyond 30 Gy.
Radiology
null
17550dac-7d45-4e1d-ac9b-9119ac35fbfe
Which of the following statement regarding Rota virus is false?
Most commonly affects children
Double stranded RNA virus
It is a non enveloped virus
None of the above
3d
multi
Rota virus is a double stranded RNA virus belonging to the family Reoviridae. The RNA is enclosed in a triple layered, non enveloped icosahedral capsid. It is one of the commonest cause for watery diarrhoea in children. Oral rehydration therapy is the most appropriate treatment of choice.
Microbiology
null
1df59731-5911-4f76-84b0-af31326e3b96
Which of the following phospholipid is associated with apoptosis?
Phosphatidylcholine
Dipalmitoyl Phosphatidylcholine
Phosphatidylserine
Phosphatidylinositol 4,5-bisphosphate
2c
single
Lipid bilayer is asymmetric. Phosphatidylserine and phosphatidyl ethanolamine are located in the inner leaflet Lecithin and sphingomyelin are located in the outer leaflet. Flipping of phosphatidylserine to outer membrane is seen in apoptosis. This is the basis of annexin V assay
Biochemistry
Chemistry of Lipids
7cfa5fe7-ec5c-49e3-9e0e-de168a93eb92
Which of the following malignancy is associated with invasion of Voex Vein?
Retinoblastoma
Malignant melanoma
Optic nerve gliomas
Medullo-epitheliomas
1b
single
Malignant melanoma of the choroid is the most common primary intraocular tumor of adults usually between the age group 40-70 years. It is rare in blacks and is more common in whites. It arise from the neural crest derived pigment cells of the uvea as a solitary tumor and is usually unilateral. This tumor during the sta...
Ophthalmology
null
470f8c6c-20e6-4251-9931-79116a602ced
A Female health worker has to teach women in Urban slum about ORS preparation. Best method will be
Lecture
Flipcha
Demonstration
Workshop
2c
single
Demonstration -Is a carefully planned presentation where idea is to show ' how to perform' a skill/procedure Two principles : 1. Seeing is believing 2. learning by doing
Social & Preventive Medicine
HC Methods, D-P Communication
3bedb51a-0d6c-415e-ba51-63f285715532
Which of the following Inhalation anaesthesia agent is Hepatotoxic:
Sevoflurane
Isoflurane
Halothane
Procaine
2c
single
Side effects of inhalation anesthetics Halothane: Auto immune hepatitis Disrupts dual blood supply Respiratory depression Sevoflurane Produce Comp A (nephrotoxic) Day care surgery Inhalational induction agent of choice Pediatric population Isoflurane Coronary steel phenomenon Procaine Local anesthetic Used in cataract ...
Anaesthesia
FMGE 2018
ad10cb42-e1a4-46c2-aae7-5117a6ed9c7d
Degenerated neurofilaments seen in patients with Alzheimer's disease are:
Hirano bodies
Lipofuscin granules
Neurofibrillary tangles
Amyloid plaques
2c
single
Neurofibrillary tanglesThe build-up manifests in two ways:Plaques- deposits of the protein beta-amyloid that accumulate in the spaces between nerve cells Tangles - deposits of the protein tau that accumulate inside of nerve cellsBoth amyloid plaques and neurofibrillary tangles are clearly visible by microscopy in brain...
Psychiatry
null
95a15814-9dde-47b4-952a-c533b4c00180
Pepsinogen is secreted by
Parietal cells
Mucus cells
Chief cells
Oxyntic cells
2c
single
Chief or zymogen or peptic cells secrete pepsiongens.Parietal or oxyntic cells secrete HCl and intrinsic factor.These cells are located in the body of stomach, including the fundus.(Ref: Ganong&;s Review of medical physiology, 23 rd edition, page 431)
Physiology
G.I.T
d5c83c8d-2fad-4e4c-bb1a-5ddc9b848487
In the work of breathing, tissue resistance contributes ___% fraction:
7%
14%
28%
65%
0a
single
Work done = load x displacement. In the context of lungs, load is analogous to pressure and displacement is volume expansion of lungs. Hence, work of breathing = DP X DV. Thus, work done can be calculated as area covered under the inspiratory curve in compliance diagram. Of the total inspiratory work, 65% work is elast...
Physiology
Respiratory System Pa 1
cf6c0563-55e8-4149-9401-7be2d7a5942d
Snow banking is typically seen in:
Pars planitis
Endophthalmitis
Coat's disease
Eale's disease
0a
multi
A i.e. Pars planitis Pars planitis (intermediate uveitis) presents with snow ball opacities Q which coalesce to form a grey white plaque called snow banking Q
Ophthalmology
null
c2780510-d57d-40b0-bdfa-a5cb64397acd
Non visualization of gastric fundic bubble with air-fluid level in retrocardiac region suggests:September 20003
Carcinoma esophagus
Esophageal web
Achalasia cardia
Congenital hyperophic pyloric stenosis
2c
single
Ans. C i.e. Achalasia cardia
Radiology
null
1f0a7819-df2d-4d63-aafc-62590c3d3510
Which of the ITIowing mosquitoes is invohed in the spread of-Japanese encephalitis ?
Aedes
Anopheles
Culcx
Mansonoides
2c
single
Ans. is 'c' i.e., Culex
Social & Preventive Medicine
null
df16eb83-a248-4c24-9b26-604763328694
Which of the following is a content of dentinal tubules
Odontoblastic process
Afferent nerve terminal
Dendrites of Antigen presenting cells
All
3d
multi
Contents of Dentinal tubule Odontoblastic process Afferent Nerve terminal Dendrites of antigen presenting cell Dentinal fluid intratubular dentin
Dental
null
e35c2117-7846-495d-b1d0-4c12cdbc8cd7
Reducing sugar in urine can be detected by ?
Benedicts test
Fehling solution
Glucose-oxidase test
All of the above
3d
multi
Ans. is 'd' i.e., All of the aboveDetection of reducing sugars Reducing propey of sugars in alkaline solution is utilized for both qualitative and quantitative determination of sugars. Reagent containing Cu' ions are most commonly used. These are generally alkaline solution of cupric sulfate :-Benedict's quantitative r...
Biochemistry
null
d73ffecb-2adb-4a85-b060-741f57d2d182
Ulcerative colitis what is seen?
Cryptitis
Crypt loss
Crypt branching
Proliferating mucosa
0a
single
Cryptitis The pathology in ulcerative colitis typically involves distoion of crypt architecture, inflammation of crypts (cryptitis), frank crypt abscess, and hemorrhage or inflammatory cells in the lamina propria. Pathology of ulcerative colitis. Macroscopic features Ulcerative colitis is a mucosal disease that usually...
Pathology
null
5d57e27e-f21f-4078-a981-d61e610bd320
Parachute reflex disappears by: March 2013 (c, f)
1 year
2 years
3 years
Persists forever
3d
single
Ans. D i.e. Persists Parachute (forward) reflex When:This occurs from about 9 months of age and persists. What:If the baby is held in a position where he is dropped forward, he will outstretch his hands. This is one of the baby milestones that is protective for falling.
Pediatrics
null
4eaf53a8-d38a-4a3f-b52b-b801aa99f4c0
All are true regarding vitamin D, except ?
Sunlight is impoant
1-hydroxylation in liver
Active form is calcitriol
RDA is for children is 400 IU
1b
multi
Ans. is 'b' i.e., 1-hydroxylation in liver
Physiology
null
bd33b12f-ac10-40a4-8f1a-13cf4d118e1a
Marjolin ulcer
Ca in marjolin's is squamous cell ca
Chronic venous insufficiency
Basal cell carcinoma
arise from base of the ulcer
0a
single
.marjolin&;s ulcer is the name given to a malignancy ( usually a squamous cell carcinoma ) which arise in any long standing wound or a scar mostly scar of an old burn it grows slowly as it is avascular it is painless
Surgery
General surgery
53d0fd05-9fd6-4daf-a444-47303c37a667
Proprioception is carried by which fibers?
Fasciculus cuneatus and fasciculus gracilis
Anterior spinothalamic tract
Lateral spinothalamic tract
Spinocerebellar tract
0a
single
Ans. is'a'i.e., Fasciculus cuneatus and fasciculus gracilis(Ref: Guyton 12th/e p. 573)Posterior column (Dorsal column) (Fasciculus Gracilis and Fasciculus Cuneatus) carriesProprioception (Position of body or limb, position of joint)VibrationFine touch (two point discrimination, topognosis, stereognosis).Kinesthesia
Anatomy
null
392da5ca-e097-4dc4-a8e8-b55576c97d75
Persistent bucconasal membrane result in
Cleft lip
Choanal atresia
Cleft palate
T-O Fistula
1b
single
Ans. b (Choanal atresia). (Ref. Diseases of ENT, PL Dhingra, 3rd ed., 78, 210, 510)# Persistant bucconasal membrane leads to choanal atresia.Choanal atresia# Is a autosomal recessive trait in which the posterior choanae unilaterally or bilaterally fail to develop properly.# Persistent bucconasal membrane is the basic e...
ENT
Nose and PNS
0a8d08fb-bad1-4046-9ec6-62534715a204
Empirical treatment for meningococcal meningitis is:
Ceftriaxone
Cefotetan
Gentamicin
Cefoxitin
0a
single
Ans. (A) Ceftriaxone(Ref: Harrison 19/e p767)Drug of choice for treatment of meningococcal meningitis is Penicillin G. But for empirical treatment we need to cover other likely organisms too. So, ceftriaxone is preferred that will also cover H. influenzae. Vancomycin is usually added to cover other organisms also.
Pharmacology
Chemotherapy: General Principles
e0d81130-bfb6-419a-b679-74f1a859bf0b
Pheochromocytoma are tumours of:
Adrenal cortex
Adrenal medulla
Pancreas
Bone
1b
single
Ans. B. Adrenal medullaPheochromocytoma are a type of tumor of the adrenal glands that can release high levels of epinephrine and norepinephrine. As the name implies, the "ad-renal" glands are located near the "renal" area. Someone with a pheochromocytoma usually has three classic symptoms, headache, sweating, and hear...
Biochemistry
Endocrinology
332403aa-b8d2-4552-aafa-8097f8e9d843
Primary peritonitis is more common in females because :
Ostia of Fallopian tubes communicate with abdominal cavity
Peritoneum overlies the uterus
Rupture of functional ovarian cysts
None of the above
0a
multi
Ans. is a i.e. Ostia of fallopian tubes communicate with abdominal cavity Primary peritonitis refers to inflammation of peritoneal cavity without a documented source of contamination. "It occurs more commonly in children than adults and in women than in men. The later distribution is explained by entry of organisms int...
Gynaecology & Obstetrics
null
a85064ea-a586-4021-8880-493772698a71
Rhomboid major is supplied by which type of neuron-
Unipolar
Pseudounipolar
Bipolar
Multipolar
3d
single
Ans. is 'd' i.e., Multipolar * All skeletal muscles are supplied by motor neurons which are multipolar neurons.* There are following types of neurons1) Unipolor neurons These neurons have one process, with different segments (of that one process) serving as dendrite (receptive surfaces) as well as axons (releasing term...
Physiology
Nervous System
b63b2fe1-285d-493b-880b-c518a5aceb20
SIADH secretion is seen in all except -
Meningitis
Interstitial Nephritis
Hypothyrodism
lung cancer
1b
multi
Ref - geekymedics.com
Medicine
Endocrinology
52377123-bb22-4adc-96a9-285a4699d291
The most easily perforated tooth with a slight mesial or distal angulation of bur after a mandibular central incisor is:
Maxillary premolar
Maxillary molar
Mandibular premolar
Maxillary canine
0a
single
null
Dental
null
d5fd5a26-4d40-41f7-9b85-e25275807ef9
All of the following provisions are included in the primary health care according to the Alma Ata declaration except
Adequate supply of safe drinking water
Provision of food supply
Provision of free medicines
Basic sanitation
2c
multi
Ans. c. Provision of free medicines Primary Health Care The Alma Ata Conference has defined primary health care as -- an essential health care made universally accessible to individuals and acceptable to them, through their full paicipation and at a cost the community and country can The Alma -- Ata Declaration has out...
Social & Preventive Medicine
null
6b301571-46fe-409a-bda8-80d146e8aa66
True about first order kinetics is:
A constant amount is eliminated in unit time
The half-life increases with an increase in dose
The rate of elimination is constant
The rate of elimination is proportional to the plasma concentration
3d
multi
Ans. d. The rate of elimination is proportional to the plasma concentration (Ref: Katzung 12/e p43-44: KDT 7/e p30-31, 6/e p31-32)Rate of elimination is proportional to plasma concentrationQ first order kinetics (Linear kinetics).First Order Kinetics (Linear kinetics)Zero Order Kinetics (Non linear Kinetics)* Constant ...
Pharmacology
Pharmacokinetics
eceae43d-d926-44b3-a3d9-b4e8184a6df7
A 35-year-old female presents with recurrent renal stone. What is not advised?
Increase water intake
Restrict protein
Restrict salt
Restrict calcium
3d
single
Low-calcium diets increase the risk of the incident stone formation. Low-calcium diets lead to the stone formation by reducing the amount of calcium to bind oxalate in the intestine- | urine oxalate levels.
Medicine
Kidney Stones & Renal Tubular Acidosis
8a034771-38cb-4cd8-a500-08dd26fce343
The tensile strength of wound after laparoscopic cholecystectomy in a 30 years old woman depends upon:
Replacement of type 3 collagen
Macrophage aetivity/snvasion
Extensive crosslinking of tropocollagen
Granulation tissue
2c
single
The recovery of tensile strength results from the excess of collagen synthesis over collagen degradation during the first 2 months of healing, and, at later times, from structural modifications of collagen fibers (cross-linking, increased fiber size) after collagen synthesis ceases. 'Recovery of Tensile Strength: Fibri...
Pathology
null
ba8c36f0-dd42-44b5-bf6e-e3be83fe672a
A 53-year-old woman with known kidney disease presents to a hospital because her pain has become increasingly more severe. A physician performing kidney surgery must remember that:
The left kidney lies a bit lower than the right one
The perirenal fat lies external to the renal fascia
The renal fascia does not surround the suprarenal gland
The left renal vein runs anterior to both the aoa and the left renal aery
3d
multi
The left renal vein runs anterior to both the aoa and the left renal aery.. The right renal aery runs behind the IVC and is longer than the left renal aery. Because of the large size of the right lobe of the liver, the right kidney lies a little lower than the left kidney. 4 coverings around the kidney from inside to o...
Anatomy
GIT 1
06bbd2f9-2c3d-4fd6-afef-1b5830f43ff5
The major role of 2,3 DPG in RBC includes
Binding of O2
Release of O2
Acid base balance
Reversal of glycolysis
1b
single
The normal BPG in the blood keeps the O2-hemoglobin dissociation curve shifted slightly to the right all the time. In hypoxic conditions that last longer than a few hours, the quantity of BPG in the blood increases considerably, thus shifting the O2-hemoglobin dissociation curve even faher to the right. This shift caus...
Physiology
Cardiovascular system
cce8ac92-41f6-4ccf-a26d-0b215c93f624
A lady on long term hemodialysis developed carpel tunnel syndrome. The cause was diagnosed to be amyloidosis by using a biopsy. What is the type of amyloid that is seen?
Beta 2 microglobulin
Amyloid light chain
ATTR
Serum amyloid associated protein
0a
single
Ans. is 'a' i.e. Beta 2 microglobulin Dialysis-related amyloidosis (DRA) is a disorder caused by tissue deposition of beta2 microglobulin as amyloid fibrils.The clearance of beta2 microglobulin, a component of the major histocompatibility complex that is present on cell surfaces, normally occurs by glomerular filtratio...
Pathology
Histo Pathology
5ce8d49b-7ce5-4408-b923-3147bfc6eafc
Contrast used for MRI –
Iodine
Gadolinium
Metvazamide
Pmnipaque
1b
single
Gadolinium is the most commonly used MR contrast agent.
Radiology
null
5af8df70-a728-4d9b-8272-a491056f70a3
True about diabetic mother is :
Hyperglycemia occurs in all infants of diabetic mothers
High incidence of congenital hea anomalies is common
Small baby
All
1b
multi
Ans. is b i.e. High incidence of congenital hea anomalies is common
Gynaecology & Obstetrics
null
0671b28e-5cb9-43ce-b4d2-3bc210e95a2e
Earliest presentation of Friedrich's ataxia is?
Ataxia
Seizures
Optic atrophy
Stuttering
0a
single
Answer is A (Ataxia): In most patients ataxia of gait and stance is the first manifestation of the disease.- Clinical Neurology by Goetz 2"d/742 Friedreich's ataxia presents with progressive staggering gait, frequent falling and titubation- Harrison Note: The first pathological changes in Friendreich's Ataxia are thoug...
Medicine
null
10dbcd2f-df37-4901-96ed-35486a392340
Laproscopic tubal ligation contraindication -
Post partum state
Post MTP
Gynaecologic malignancies
3 previous childbirth
0a
single
Ans. is 'a' i.e., Postpartum state "The operation is done in the interval period, concurrent with the vaginal termination of pregnancy or 6 weeks following delivery. Should not be done within 6 weeks following delivery."
Unknown
null
bbceed07-b205-46b6-9933-7defdc90010b
All are the Complication of CVP line except -
Airway injury
Haemothroax
Air embolism
Septicemia
0a
multi
IMMEDIATE: Failure of procedure Pneumothorax Haemothorax Retroperitoneal haematoma Aerial puncture Local haematoma Guidewire-induced arrhythmia Thoracic duct injury Guide wire embolism Air embolism EARLY: catheter blockage chylothorax catheter knots LATE: Infection : 2.5 infections/ 1000 catheter days catheter fracture...
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
62620647-6c10-462a-af18-c531291d8a0d
which of the following is derived from surface ectoderm-
Iris
Sclera
Lens
Optic nerve
2c
single
Ans. is 'c' i.e., Lens PrecursorDerivativesNeural ectodermSmooth muscle of the iris, opticle vesicle and cup, iris epithelium, ciliary epithelium, Part of the vitreous, Retina, Retinal pigment epithelium, fibres of the opric nerve.Surface ectodermConjunctiva] epithelium , Corneal epithelium. Lacrimal glands, Tarsal gla...
Ophthalmology
Anatomy
a847371a-b9f1-4edb-a9b9-4bec0653d804
Golden S is seen in
Left upper lobe collapse
Pleural Effusion
Left lower lobe collapse
Bronchogenic carcinoma
3d
single
Golden "S" sign is a Reverse "S" sign seen on Frontal Chest Radiograph In patients with Bronchogenic Ca with Right Upper lobe collapse Lower convexity of the Reverse S is due to the mass Upper concavity of the "S" is due to Right UPPER LOBE atelectasis with the upward shifting of the horizontal fissure.
Radiology
Respiratory Radiology