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135
2d5b2c7e-9ab1-420d-b016-c5cbec17bb76
Vaccine is what level of prevention
Primordial
Primary
Secondary
Tertiary
1b
single
All vaccines/immunization are primary level of prevention.
Social & Preventive Medicine
null
2f31c612-b471-449a-9258-a7a81ccc545d
Antrochoanal polyp arise from?
Ethmoid sinus
Maxillary sinus
Frontal sinus
Sphenoid sinus
1b
single
ANSWER: (B) Maxillary sinusREF: Dhingras ENT 5th ed p-188, 4th edition page 164See table of "DIFFERENCES BETWEEN ANTROCHOANAL AND ETHMOIDAL POLYP" in ENT December 2009
ENT
Polyp
e3505cbe-26ca-49d1-8fd2-8857725c3e37
Police inquest is A/E
Senior head constable can investigate
Most common inquest
Panchnama has to be signed by IC)
10 may not summon
3d
single
D i.e. 10 may not summon
Forensic Medicine
null
938c243c-28f7-475c-b144-66da2f8b2a96
ACTH secretion is highest during –
Noon
Evening
Morning
Night
2c
single
Cortisol levels in blood are normally elevated at 8.00 AM and decrease to less than 50% by midnight.
Pediatrics
null
eafa7d0d-c7f3-4f72-96c9-62c9f9a81f9e
If there are 4 nucleotides instead of 3 in codon, how many amino acids may be formed?
16
21
256
64
2c
single
C i.e. 256
Biochemistry
null
7410d491-9dfa-43c6-86ce-e392d2416357
Following causes distension of abdomen-a) Hirschsprungsb) Hypokalemiac) Hyperkalemiad) Hypomagnesmia
acd
bcd
abc
abd
3d
single
null
Medicine
null
22f97444-0a8d-47f1-9726-14c4671d1406
Biopsy findings of celiac disease all of the following, except
Crypt hyperplasia
Villous atrophy
Mucosal atrophy
Intraepithelial lymphocytes
2c
multi
Answer is C (Mucosal atrophy) Mucosa! atrophy and presence of Giardia lambia are not seen in biopsy front celiac disease. Small Intestinal Biopsy (duodenal /jejunal) in Celiac disease (Characteristic but not diagnostic()) Absence or reduced height of villi (Flat appearance)() Crypt hyperplasia, villous atrophy (but not...
Medicine
null
a8bc20e6-fac5-41cb-93f7-20cca024cbab
Most common tumor of urinary bladder is ?
Sq. cell carcinoma
Adeno carcinoma
Transitional carcinoma
Str. squamous carcinoma
2c
single
Answer is 'c' i.e. Transitional cell carcinoma There are 3 common histological types of bladder cancer a) Transitional (urothelial) cell ca -- 90% b) Squamous cell ca -- 5-10% c) Adenocarcinoma -- 2%
Surgery
null
87b32955-e809-4bf9-88d8-6175336fdae0
A village health guide is selected by
Panchayat
Zilla parishad
Block Development Officer
Medical Officer in-charge
0a
single
Health guides come from and are chosen by the community they work.They should be permanent residents of local community, have formal education up to 6th standard, acceptable to all sections, spend 2-3 hrs for community health work.Park 23e pg: 902
Social & Preventive Medicine
Health care of community & international health
618452cf-42c6-4dca-8707-4f66b44d0db5
All of the following are associated with coombs positive hemolytic anemia except -
Thrombotic thrombocytopenia purpura (TTP)
Scleroderma
SLE
PAN
0a
multi
Coombs is positive only in immune hemolytic anemias where there is hemolysis of RBCs by antibodies produced in the body which is the case in SLE ,PAN & Scleroderma. While in TTP hemolysis occurs due to trauma to RBCs due to Microangiopathic hemolysis, seen in TTP &HUS Ref Robbins 9/e pg 448-449
Pathology
Haematology
5d3fe1d3-46c4-4c58-823f-d6b9d9e5ae0b
Which of the following is NOT a tocolytic agent?
Nifedipine
MgSO4
Dinoprostone
Terbutaline
2c
single
The inhibition of uterine contractions, or tocolysis, has been the mainstay therapy for pre-term labour. Specific tocolytic agents are adrenergic receptor agonists Terbutaline, Ritodrine), MgSO4, Ca2+ channel blockers (Nifedipine), COX inhibitors, oxytocin-receptor antagonists, and nitric oxide donors. Two forms of pro...
Pharmacology
null
ba32557d-179a-4a95-a467-6d3388a2f8d7
What is the most likely cause of this physical finding?
Ascariasis
Esophagogastric bypass
Hirschsprung's disease
Acute intestinal pseudo-obstruction
1b
single
Answer B. Esophagogastric bypassEsophagogastric bypass is the correct answer. This patient had an subcutaneous esophagogastric bypass procedure over 50 years ago as a result of a complete esophageal stenosis due to a chemical burn. The examination finding is notable for the subcutaneous colonic segment on the chest wal...
Medicine
G.I.T.
267c59ce-118f-4baf-acf1-1eec00b4c858
IOC for urethral trauma:
Ascending urethrogram
Descending urethrogram
USG
CT scan
0a
single
Ans. (a) Ascending urethrogramRef: Bailey and Love 27th Edition, Page 1479* Most common urethral injury sites caused by external trauma are bulbar and membranous urethra.* Most common cause of urethral trauma: Catheterization and cystoscope induced.* IOC for urethral injuries is by ascending urethrogram using water sol...
Surgery
Urethra & Penis
8c9ecaeb-6415-4fb4-88f4-dd7d7216b36a
Tamoxifen is useful in:
Carcinoma prostate
Carcinoma ovary
Estrogen receptor positive breast carcinoma
Seminoma
2c
single
null
Pharmacology
null
4412f8ba-be82-454b-936f-da13dac0402f
Urate crystals are deposited in small joints of the hands & feets in: September 2003
Gout
Still's disease
Retropharyngeal abscess
Ankylosing spondylitis
0a
multi
Ans. A i.e. Gout
Surgery
null
d664a032-6045-4079-bd0c-f7e5d86d4722
In the calculation of Years of Potential Life Lost (YPLL), the denominator is-
Population under 75 years of age
Midyear population
Population in the ages of 15 to 65 years
Population above 15 years of age
0a
multi
Years of potential life lost (YPLL)/Potential years of life lost (PYLL) An estimate of the average years a person would have lived if he or she had not died prematurely. It is a measure of premature moality/death. Deaths occurring in individuals age 75 or older are NOT included in the calculation. For YPLL calculation,...
Social & Preventive Medicine
PQLI, HDI, MDPI, BPL
0e9b9822-5a51-480b-9c9a-3ef7fc89b686
A 46-year-old woman presents with fever, hemoptysis, weight loss, and night sweats. She has never smoked. She recently returned returned from a month-long trip to Asia. A chest radiograph reveals apical lesions with cavitation in the left lung. A purified protein derivative (PPD) test is placed, and 48 hours later an 1...
Acquired immunodeficiency syndrome
Congenital immunodeficiency
Miliary tuberculosis, with seeding of distal organs with innumerable small millet seed-like lesions
Secondary tuberculosis, resulting from activation of a prior Ghon complex, with spread to a new pulmonary site
3d
multi
Tuberculosis, at one time a frequent hazard in the United States, is now relatively uncommon except in immunocompromised individuals Primary tuberculosis is the initial infection by M. tuberculosis, and is restricted to the primary, or Ghon complex. Cavitation and selective localization to the pulmonary apices are char...
Pathology
Systemic Pathology
0d1f407b-9c60-4f7c-b3e9-1e1325a42cbb
High Viscosity GIC was discovered in?
1990
1980
1970
2000
0a
single
null
Dental
null
9e59ad74-7078-4c2b-9656-a1df58d50955
Most sensitive test for antigen detection is -
RIA
Elisa
Immunofluorescence
Passive hemagglutination
0a
single
RIA is a competitive binding assay in which fixed amounts of antibody and radiolabelled antigen react in the presence of unlabeled antigen. The labeled and unlabeled antigens compete for the limited binding sites on the antibody. This competition is determined by the level of the unlabelled antigen present in the patie...
Microbiology
Immunology
13542b08-c3d8-4cfb-8889-f1381c237086
True negative means-
Sensitivity
Specificity
Positive predictive value
Negative predective value
1b
multi
Ref:Parks 23rd edition pg 136 specificity is defined as the ability of a test to identify those who do not have the disease. That is true negatives.
Social & Preventive Medicine
Biostatistics
d004bc4f-2aa1-46ea-9ed1-33bbc4a2a698
Most common cause of gastric varices is:
Splenic vein thrombosis
Splenectomy
Cirrhosis
Mesenteric thrombosis
2c
single
Ans. (c) CirrhosisRef: Sabiston 19/e p 1222-1223* MC cause of Isolated Gastric varices- Splenic vein thrombosis* MC cause of gastric varices- Cirrhosis* Gastric Varices are in the SUBMUCOSA (Esophageal varices are seen in MUCOSA)* Endoscopic USG is the IOC to diagnose Gastric Varices because of the reason above.* Endos...
Surgery
Liver
c9fb4704-224b-4ebb-aaf8-32f33f5aafb4
During the first 6 months of lactation, which amongst the following contraceptives is not advisable?
DMPA
Combined oral contraceptives pills
Progestin only pills
Norplant
1b
single
- Combined oral contraceptives are relatively contraindicated in the first six months of delivery, as they decrease breastmilk output. - Progestin-only methods can be used after 6 weeks of delivery safely as they have little to no effect on lactation post-six weeks.
Social & Preventive Medicine
Natural Methods, Barrier Methods, IUDs, OCPs
99efb380-50e5-4abf-bfa0-1ae2da2aa615
Expression of which of the following oncogene is associated with a high incidence of medullary carcinoma of thyroid:
FOS
BRAF
RET Proto oncogene
WNT1
2c
single
Inherited Medullary Thyroid Cancer: In inherited medullary thyroid cancer prospective family screening is essential due to the 90 to 95% penetrance of the disease. Inherited MTC is usually present by the third decade of life. Inherited syndromes of medullary thyroid cancer are all transmitted in an autosomal dominant f...
Medicine
null
360e653e-5722-4bf1-a3d3-2083c529cf91
commonest site of a rodent ulcer is -
Limbs
Face
Abdomen
Trunk
1b
single
Ans. is 'b' i.e., Face o Rodent ulcer is synonymous with basal cel! carcinoma.o 90% of basal cell carcinomas are seen in the face, above a line from the corner of mouth to the lobule of ear. The commonest site is around the inner can thus of the eye (also k/a Tear cancer).o This is a typical appearance of nodular varie...
Pathology
Skin
69474b7f-9499-4a09-9722-bf2015728fc8
Early sign of glaucoma includes following except;
Nerve fibre atroiphy
Peripheral halo
Veical cup
Horizontal cup
3d
multi
D i.e. Horizontal cup Veically oval cup is seen in early glaucoma where as marked (total) bean pot cupping is seen in advanced glaucoma Q
Ophthalmology
null
531f514f-bfde-4e8c-a49f-84acdc59bf9a
Warthin Finkleday giant cells are seen in:
LGV
Measles
Mumps
Rubella
1b
single
Ans: b (Measles)The cytopathic effects of measles include1) Multinucleate syncitium formation2) Acidophilic cytoplasmic & nuclear inclusion bodies3) Multinucleate giant cells (Warthin Finkleday cells)More about measles* Commonest childhood exanthema (Mobili virus)* Characteristic Koplik spots are seen opposite to upper...
Microbiology
Virology
884bb6f3-a0ce-4ec3-86ef-dd71f0c48e9c
The main cause of increased blood flow to exercising muscles is :
Raised blood pressure
Vasodilatation due to local metabolites
Increased sympathetic discharge to peripheral vessels
Increased hea rate
1b
single
B i.e. Vasodilatation due to local metabolites
Physiology
null
e8b9e66f-8290-4410-908a-dead1e4f8f15
All are germ cell tumours of ovary EXCEPT :
Brenner's tumour
Dysgerminoma
Polyembryoma
Endodermal sinus tumor
0a
multi
Brenner's tumour
Gynaecology & Obstetrics
null
ac2ce0ab-3188-4236-8bcf-d03f904be249
Which phase of the cell cycle is resistant to most chemotherapeutic agents, i.e., those that are classified as phase-specific?
G0
G1
G2
M
0a
single
.
Pharmacology
All India exam
76387746-2b1e-438d-a80e-ff7e2a4aab14
Hypehermia is defined as-
Core temperature > 40.0degC
Core temperature > 41.50degC
Elevated temperature that normalizes with antipyretic drugs
Uncontrolled increase in body temperature despite a normal hypothalamic temperature setting
3d
single
Hypehermia is increase in the body temperature to abnormal level despite of normal hypothalamic functions The body temperature may be over 105 F, a level that damages the brain and other organs. Other symptoms include muscle cramps, fatigue, dizziness, headache, nausea, vomiting, and weakness. The hea rate may be eleva...
Medicine
Miscellaneous
48d71756-1bba-4675-8496-f0a617cdf84d
USG can detect gestation sac earliest at –
5–6 weeks of gestation
7–8 weeks of gestation
10 weeks of gestation
12 weeks of gestation
0a
single
The gestational sac can be visualized as early as 41/2 weeks by transvaginal USG and 5 weeks by transabdominal USG.
Radiology
null
be8dc1e6-9eef-4996-8fea-c773d78729c3
Physical Quality of life Index Components
Life expectancy at bih
Knowledge
Life expectancy at age one
Standard of Living
2c
single
Components of PQLI:Infant Moality Life expectancy at age oneLiteracyPQLI is scaled from 0 to 100.
Social & Preventive Medicine
Concept of health and disease
dc464c02-d6de-4ff3-8430-652ee6225f8f
Positive health indicators of nutritional status include all of the following EXCEPT:
Anthropometric measurements of pre-school children
Height of school children at school entry
Weight of antenatal mothers
Prevalence of low bih weight
2c
multi
(Weight of antenatal mothers) Nutritional status indicators Nutritional status is a positive health indicator. Three nutritional status indicators are considered impoant indicators of health status: a. Anthropometric measurements of pre-school children b. Height of school children at school entry c. Prevalence of low b...
Surgery
null
78a6de28-a173-4bd5-b9db-4d95655fa962
Ischial bursitis is also known as ?
Clergyman's knee
Housemaid's knee
Weaver's bottom
Students elbow
0a
single
Ans. is 'c' i.e., Weaver's bottom Prepatellar bursitis Hrdeg,1semaid's knee Infrapatellar bursitis Clergyman's knee Olecranon bursitis Student's elbow Ischia] bursitis Weaver's bottom On lateral malleolus Tailor's ankle On great toe Bunion
Surgery
null
6752e8f2-c5e1-4b3c-9c03-a972d7262045
Long acting non-depolarising competitive blocker is
Doxacurium
Rocuronium
Mivacurium
Atracurium
0a
single
null
Anaesthesia
Muscle relaxants
22b2d46b-8578-4ca7-8e69-9367f1d77287
Which of the following drugs is most frequently used in treating refractory periodontitis, including localized juvenile periodontitis?
Metronidazole and Amoxicillin
Tetracycline
Ciprofloxacin
Penicillin
0a
single
null
Dental
null
fb070130-bc61-44d6-b500-53bd61f0737f
Gene affected in breast cancer?
WT1
p53
RAS
p83
1b
single
Ans. is 'b' i.e., p53 * Most common gene involved infamilial breast cancer - BRCA-1* Most common gene involved in sporadic breast cancer -p53* Most common gene involved overall (Hereditory plus sporadic) - p53* Maximum increase in susceptibility to breast cancer is seen with - p53 mutation (>90%) whether it is sporadic...
Pathology
Breast
7b1f9a00-629f-4d15-9965-a1bc9e625482
A 50 year old woman, Hema has been diagnosed with locally advanced breast cancer and recommended for chemotherapy. She has five years history of myocardial infarction and congestive heart failure. Which antineoplastic drug should be best avoided
Anthracycline
Alkylating agent
Platinum compound
Bisphosphonates
0a
multi
Anthracyclines like Doxorubicin, Daunorubicin, Idarubicin and Epirubicin are implicated in causing cardiotoxicity. This adverse effect is due to the generation of iron mediated free radicals. Dexrazoxane is a free radical scavenger that can be used to prevent cardiotoxicity due to anthracyclines.
Pharmacology
null
72b6ce27-9eab-4d41-a127-69c9a3a8887c
All are examples of malignant disorders causing myelofibrosis except ?
Chronic myelogenous leukemia
Hairy cell leukemia
Hodgkin's disease
PNH
3d
multi
Disorders Causing Myelofibrosis Acute leukemia (lymphocytic, myelogenous, megakaryocytic) Chronic myelogenous leukemia Hairy cell leukemia Hodgkin's disease Idiopathic myelofibrosis Lymphoma Multiple myeloma Myelodysplasia Polycythemia vera Systemic mastocytosis Ref: Harrison, E-18,P-905.
Medicine
null
c39cc9c6-f7de-4c8e-a67f-57745beb1d9b
Use of lithium in pregnancy can result in which of the following abnormalities in the baby?
Anencephaly
Ebstein's anomaly
Caudal dysgenesis syndrome
Elfin facies
1b
single
Lithium usage in pregnancy can lead to Ebstein's anomaly cardiovascular defects.
Psychiatry
null
e5cbe988-6d56-422d-b058-994332876549
Non-visualization of Gallbladder is a feature seen in case of Acute cholecystitis in which of the following investigations?
HIDA scan
USG abdomen
CECT abdomen
MRCP
0a
multi
Acute cholecystitis on HIDA scan - failure to visualise gall bladder even after 60 min / delayed visualisation after 4 hrs
Anatomy
All India exam
b9cd8af8-420f-4db1-845f-71476249a4e6
Middle ear deafness can be tested by
Babinsky test
Chvostek test
Finger-nose test
Weber's test
3d
single
null
Physiology
null
a8e10f2c-95fa-4da7-9ebe-1fe0f659e128
Post-term labor is seen in:
Hydramnios
PID
Anencephaly
Multiple pregnancy
2c
single
Ans. is c, i.e. AnencephalyRef. Dutta Obs. 9/e, p 299Causes of Post-term pregnancy:Wrong dates: Due to inaccurate LMP (most common).Biologic variability (Hereditary) may be seen in the family.Maternal factors: Primipara/elderly multipara/H/o previous prolonged pregnancy, sedentary habit.Fetal factors: Congenital anomal...
Gynaecology & Obstetrics
Normal Labour
ea6c4eab-28c0-4094-832b-32ddef410236
The most common presentation for IgA nephropathy is:
Nephritic syndrome
Nephritic syndrome
Microscopic hematuria
Repeated gross hematuria
3d
single
Answer is D (Repeated Gross Hematuria): The most common presentation of IgA Nephropathy is with recurrent episodes of Gross (Macroscopic) Hematuria during or immediately following an upper respiratory tract infection 'Recurrent attacks of Painless Gross Hematuria represent the classic clinical presentation of IgA Nephr...
Medicine
null
4e181d8f-97c0-40b6-894c-24571061a847
The classification proposed by the International Lymphoma Study Group for non - Hodgkin's lymphoma is known as -
Kiel classification
REAL classification
WHO classification
Rappaport classification
1b
single
null
Medicine
null
4d79ee25-2539-41a5-969a-9a61f7a27580
Aschoff bodies in the myocardium are the hallmark of carditis associated with
Infective endocarditis
Rheumatic fever
Rheumatoid ahritis
Systemic lupus erythematosus
1b
multi
Acute rheumatic fever is characterized by discrete inflammatory foci within a variety of tissues. The myocardial inflammatory lesions--called Aschoff bodies--are pathognomonic for rheumatic fever these are collections of lymphocytes (primarily T cells), scattered plasma cells, and plump activated macrophages called Ani...
Pathology
Cardiovascular system
d5b054aa-2d01-4c3e-b0bf-9d0b7719bc1e
Essential Pentosuria is due to defect in?
Glycolysis
HMP Shunt
TCA Cycle
Uronic acid pathway
3d
single
Affected individuals excrete large amounts of L-xylulose in urine. Xylulose being a reducing sugar gives Benedict's test positive. Bial's test is positive as xylulose is a pentose Reference Harper's Illustrated Biochemistry 30th Edition Pg 205
Biochemistry
Metabolism of carbohydrate
6ea99ce8-03c0-472f-b19b-5be32c600f39
In a woman on subdermal progesterone implant, the menstrual abnormality seen is :
Menorrhagia
Metrorrhagia
Polymenorrhoea
Amenorrhoea
1b
single
Ans. is b i.e. Metrorrhagia
Gynaecology & Obstetrics
null
bf7bc935-2e3c-4143-b784-86ff1fcfad5d
A neonate presenting with ascites is diagnosed having urinary ascites. What is the most common cause
Bilateral PUJ obstruction
Infant polycystic kidney disease
posterior urethral valve
Meatal stenosis
2c
single
Posterior urethral valves Posterior urethral valves occur in around 1 in 5000-8000 live male bihs. The valves are membranes that have a small posterior slit within them, which typically lie just distal to the verumontanum and cause obstruction to the urethra of boys. They function as flap valves and so although they ar...
Surgery
Urology
a46322fc-d4ca-4cc0-83e6-16cbe56394c6
Which of the following cranial nerve palsy leaves the eye "down and out"?
Trochlear
Oculomotor
Optic
Abducens
1b
single
CN3 lesion causes dilated pupil, down-and-out eye, droopy eyelid.
Ophthalmology
All India exam
a2331634-5450-4aa3-a870-86fe09a0ea68
Na + uptake at basolateral surface of apical cells is by -
Active transport
Passivetransport
Diffusion
Osmosis
0a
single
Ans. is 'a' i.e., Active transporto The Na+ - 1C pump operates at basolateral membrane which maintains intracellular concentration of Na+ very low.o Na+ - K+ pump is a pump for active transport.
Physiology
Transport Across Cell Membrane
2d6be52a-151c-4302-a8a3-3e44fe79b188
Most common renal tumor in neonatal period:
Renal cyst
Congenital mesoblastic nephroma
Neuroblastoma
Nephroblastoma
1b
single
"Although congenital mesoblastic nephroma (CMN) is a rare benign congenital renal tumor it is the most common solid renal tumor in the neonatal period."
Surgery
Kidney and ureter
bcdbcc6e-46cd-437c-86be-db33bb8fd31a
Antihistaminic not much preferable in motion sickness among the following is:
Cetirizine
Meclizine
Diphenhydramine
Fexofenadine
3d
single
1st generation drugs better treat motion sickness than 2nd gen drugs due to high sedating nature Fexofenadine is a 2nd gen. antihistaminic Promethazine, diphenhydramine, dimenhydrinate, and meclozine have prophylactic value in milder types of motion sickness; should be taken one hour before staing journey. Promethazine...
Pharmacology
Autacoids
242a6ed2-5fd2-40e2-a1f5-e5bbb5e5b375
"Lemon sign" & "Banana sign" are see in-
Down syndrome
Spina bifida
Turner syndrome
Periventricular leukomalacia
1b
single
Ans. is 'b' i.e. Spina bifida * Lemon and banana signs are ultrasonographic findings in a patient of neural tube defects (esp spina bifida).* The banana sign seen on axial imaging through the posterior fossa of fetus. It describes the way the cerebellum is wrapped tightly around the brain stem as a result of spinal cor...
Radiology
Nervous System
d613bddd-79ee-4661-b151-f3511c92f0c9
Which immunoglobulin is scarce in human serum
IgA
IgG
IgM
IgE
3d
single
Antibody with least serum concentration IgE(0.0004)
Microbiology
null
1f5ab534-5f91-4b27-b910-6fc20601316e
All of the following statements regarding case control study are true, except
Used to find the relative risk
Odds ratio can be calculated
Relatively cheap
Used for rare diseases
0a
multi
Using case control study only odds ratio can be calculated. Incidence rates, relative risk and attributable risk can be calculated using coho study. Case control study is inexpensive, easy to carry out, used to investigate rare diseases, used to identify risk factors, allows study of different etiological factors and i...
Social & Preventive Medicine
null
f471cbb7-7ef1-44fe-8e84-9f7247a2c3d5
Pellagra is caused by the deficiency of
Niacin
folic acid
glycin
ascorbic acid
0a
single
null
Biochemistry
null
f9f09d5b-fc6b-416a-afa8-43fc620c6369
Changes occuring in vessels in Raynauds disease are all except -
Asphyxia
Recovery
Hyperfusion
Syncope
2c
multi
Ans. is 'c' i.e., Hyperperfusion Three stages are observed with exposure to cold or emotional disturbances. These are -Stages of local syncope - On cold exposure - digital arterioles go in spasm and blood flow decreases, pallor or blanching is observed (Stage of blanching).Stage of local asphyxia - With gradual warming...
Surgery
Peripheral Arterial Occlusive Disease
640ab192-6dac-4ad3-a17b-6aba3bda3046
In which of the following cardiac structure is middle cardiac vein located?
Anterior AV groove
Posterior AV groove
Anterior interventricular sulcus
Posterior interventricular sulcus
3d
single
Posterior interventricular vein or middle cardiac vein runs in the posterior interventricular sulcus and may drain into the right atrium or into the coronary sinus.
Anatomy
null
aea61ed0-473d-42dc-a059-e4d4734a1362
A hypertensive patient was started on antihypertensive drug. He develops dry cough during the course of the treatment. Which of the following drug is responsible for the following?
Beta blockers
ACE inhibitors
Alpha blockers
Diuretics
1b
single
Ans. B. ACE inhibitorsACE inhibitorsI- C- coughII- A-angioedemaIII- P-prodrugIV- T-taste disturbanceV- O- orthostatic hypotensionVI- P-pregnancyVII- R-renal artery stenosisVIII- I-increased potassiumIX- L-low risk of diabetic nephropathy.
Pharmacology
C.V.S
a81ba95c-f9e5-467d-afc7-7e67c1d7971a
In medical ethics all is involved except
Beneficence
Confidentiality
Informed consent
Directive guidance
3d
multi
null
Dental
null
5ae5acd9-d586-4f7c-8ce7-a4b3353d2d50
A one day census of inpatients in a mental hospital could -
Give good information about the patients in that hospital at that time
Give reliable estimates of seasonal factors in admissions
Enable us to draw conclusions about the mental hospitals of India
Enable us to estimate the distribution of different diagnosis in mental illness in the local area
0a
single
Ans. is 'a' i.e., Give good information about the patients in that hospital at a time o A one day census of inpatient in a mental hospital means the examination is carried out at one point of time --> feature of cross-sectional study. o So, it will provide information about the patients in that hospital at that time. A...
Social & Preventive Medicine
null
7ef6f205-8856-46d9-8857-4308ec8d4332
Apical cyst having a direct connection with apical foramen have been termed as
Residual
Bay
Paradental
Collateral
1b
single
null
Surgery
null
25d5e21c-4900-452a-a021-c379adb0959b
'Duret hemorrhages' are seen in:
Brain
Kidney
Heart
Lung
0a
single
Ans. (a) Brain* Due to increased ICP - there will be downward herniation of brain stem which causes stretching of the Basilar artery and results in Duret hemorrhage.* Duret hemorrhage is a small area of bleeding in Upper brain stem (Midbrain and Pons)* Fatal outcome.
Surgery
Nervous System
a90f1f74-fa8f-4bc2-9d94-d25d963792c7
Preformed toxin produces diarrhea in which organism ?
Staphylococcus
Vibrio cholera
Salmonella
Escherichia coli
0a
single
Example of Preformed toxin i.e. toxin secreted in food: S.aureus enterotoxin, Bacillus cereus emetic type of enterotoxin and botulinum toxin.
Microbiology
null
1a0aa19e-5b06-4bbe-92ca-621106200813
Vitamin B12 deficiency can lead to all EXCEPT:
Myopathy
Peripheral neuropathy
Optic atrophy
Myelopathy
0a
multi
Myelin formation requires B12 If B12| - myelination | | So, 1) Peripheral neuropathy 2) Optic atrophy 3) Myelopathy But Not Myopathy 4) SACD spinal cord (Sub-acute combine degeneration of spinal cord)
Medicine
FMGE 2018
3a796bfc-f2d7-4af7-a7c7-b1b78a0296f6
Diphtheria antibody titer considered optimally protective is
>0.1 IU/ml
>0.01 IU/ml
>0.05 IU/ml
0.5 IU/ml
0a
multi
Diphtheria antibody titer considered as optimally protective is >0.1 IU/ml. Titers of IgG antibody against diphtheria toxoid vaccine reflect various levels of protection against the disease as follows: <0.01 IU/ml: No protection 0.01 IU/ml: Basic protection >0.1 IU/ml: Optimal protection. Ref: Textbook of microbiology;...
Anatomy
Bacteriology
29bb1a2f-c4e6-4e69-8a02-6adfe06ac660
True regarding X-linked recessive disorders is
Menkey's kinkey hair diseases -- Copper
Rubber man syndrome -- Lungs
Alports syndrome -- Skin
Marfans syndrome -- MS
0a
multi
(A) Menkey's kinkey hair diseases-copper # MENKES KINKY HAIR SYNDROME is an X-linked metabolic disturbance of copper metabolism characterized by mental retardation, hypocupremia, and decreased circulating ceruloplasmin. It is caused by mutations in a copper-transporting ATP7A gene. Children with this disease often die ...
Medicine
Miscellaneous
3a8735da-4140-404a-adb8-f60bc0ac9f26
Ehrlichia chaffeensis is causative agent of
Human monocytic ehrlichiosis
Human granulocytic ehrlichiosis
Glandular fever
None
0a
multi
Ehrlichiae These are gram negative, obligate intracellular bacteria which have affinity towards blood cells, They grow within phagosomes of phagocytes as mulberry-like clusters called morula. They are tick-borne. Three human infections caused by this group of organisms have been identified :-   Human monocytic ehrlichi...
Unknown
null
83208258-2d7b-47c3-887b-6bc6401021cc
An 8-year-old mentally retarded child presents with left side flank pain. On ultrasound hvperechoic lesion is seen in right kidney and multiple lesions in the liver. CT scan of abdomen shows -50 to -60 HU density of the lesions in kidney and liver. The most probable diagnosis is: (E. REPEAT 2007)
Familial angiolipomatosis
ADPKD
VHL
Tuberous sclerosis
3d
multi
Ref: Nelson's Textbook of Pediatrics, 19th edit ion. Pages 2049 and 2052Explanation:HOUNSFIELD SCALEIt is a quantitative scale for describing radiodensity.The Hounsfield scale applies to medical grade CT scans.A change of one Hounsfield Unit (HU) represents a change of 0.1% of the attenuation coefficient of water since...
Pediatrics
Nephropathy
7f503224-9e68-43fa-bd19-ec14900fcee5
In humans, rate limiting step of de novo pyrimidine synthesis is:
Aspaate tanscarbamoylase
Carbamoyl phosphate synthetase-II
Dihydro orotate dehydrogenase
Ornithine tanscarbamoylase
1b
multi
De-novo pyramidine synthesis Rate limiting step in mammals CPS II in bacteria Aspaate transcarbamoylase CPS I CPS II Rate-limiting enzyme of urea cycle Rate limiting step of pyrimidine synthesis Found in mitochondria Found in cytosol Uses ammonia as nitrogen source Uses glutamine as nitrogen source Requires N-acetylglu...
Biochemistry
Nucleotides
a460ef3b-20e8-4397-b8e1-847f1aa69880
A 60 year old man has both HTN and DM for 10 years. There is reduced vision in one eye. On fundus examination there is a central bleed and the fellow eye is normal. The diagnosis is –
Retinal tear
Optic neuritis
Diabetic retinopathy
Hypertensive retinopathy
2c
multi
Central bleed implies bleed in the macula and this is resulting in reduced vision in the involved eye. Among the given options, macular bleed can be seen in diabetic retinopathy only. In diabetic retinopathy, neovascularization of macula may occur where there is growth of abnormal blood vessels under the retina which c...
Ophthalmology
null
4eb4e5bf-33b6-4696-8443-3d28d4e7322b
OCP's intake cause psychiatric symptoms, and abdominal pain. Diagnosis is:
Acute intermittent porphyria
Systemic lupus
Thrombosis
Anemia
0a
single
Ans. is a, i.e. Acute intermittent porphyriaRef: Harrison 17th/ed, p2439Patient taking OCP's and presenting with abdominal pain and psychiatric problem, diagnosis is undoubtedly acute intermittent porphyria as OCP's can precipitate porphyria.Some drugs which precipitate porphyria are:* BarbituratesSulfonamide antibioti...
Gynaecology & Obstetrics
Contraceptives
cae1f9fd-029f-411c-b209-74dfa1e1a576
All are the potential carcinogens for hepatic angiosarcoma except :
Thorotrast
Arsenic
Polyvinyl chloride
Naphthylamine
3d
multi
Hepatic angiosarcoma carcinogen:- T :- Thorotrast A :- Arsenic P :- Poly vinyl chloride Other carcinogen :- Aflatoxin :- HCC Asbestos :- Lung cancer/ Mesothelioma Nitrosamine :- Stomach cancer. Naphthylamine:- urothelial carcinoma of bladder
Pathology
Etiological Factors of Neoplasia
26a89f5e-9d15-405e-9feb-7719c7b26716
M.C.site of Atopic dermatitis –
Scalp
Elbow
Antecubital fossa
Trunk
2c
single
Sites of itching patch in atopic dermatitis Infant Face (especially cheeks), extensors of forearm & legs. Childhood & adult → Flexures (antecubital fossa, Popliteal fossa).
Dental
null
c43116df-a3e8-47ab-a28a-48901ebc1234
Treatment options for acne vulgaris is/are -
Dapsone
Oral Minocycline
Isotretinoin
All the above
3d
multi
Ans. is 'd' i.e., All the above Drugs used for the treatment of AcneTopicalComedolytics: Act by removing the follicular plug, thereby reopen pilosebaceous ostia. Comedolytics are; Retinoic acid, Adapalene, Azelaic acid, Tazarotene.Antibiotics: Decrease bacterial population and have an anti-inflammatory effect. Topical ...
Unknown
null
4cb7c449-f3bb-4ed8-8d0f-e37fa7a045ac
A 47-year-old woman presents with increasing headaches and visual changes. On examination, her pupils are normal and reactive to light, the extraocular movements are normal, and there are visual field defects of the outer half in both eyes (bitemporal hemianopsia). Which of the following is the most likely diagnosis?
pituitary adenoma
falx meningioma
craniopharyngioma
aneurysm of the internal carotid artery
0a
multi
Adenomas of the pituitary gland constitute approximately 7% of intracranial tumors, with the chromophobic type being the most common. With macroadenomas, some degree of pituitary insufficiency is common, and half the patients have headaches. With microadenomas, the other pituitary functions may be completely normal.
Medicine
C.N.S.
e1dfaa22-1189-4d88-b52c-7c32ed9027d0
Protein A of staph aureus is pa of bacterial ?
Genome
Cell wall
Limiting membrane
Plasmid
1b
multi
Ans. is 'b' i.e., Cell wall Protein A is a cell wall component of many S aureus strains that binds to the Fc poion of IgG molecules except IgG3.The Fab poion of IgG bound to protein A is free to combine with a specific anigen. Protein a has become an impoant reagent in immunology and diagnostic laboratory technology; f...
Microbiology
null
cc2277fb-2cea-48cc-9312-2d668ee59bb1
A patient with spine, chest and abdominal injury in road traffic accident developed hypotension and bradycardia. Most likely reason is
Hypovolemic shock
Hypovolemic + neurogenic shock
Hypovolemic + Septicemia
Neurogenic shock
3d
single
Answer is neurogenic shock. It is usually due to spinal cord injury, which causes dilatation of splanchnic vessels. There will be bradycardia, hypotension, arrhythmias, and decreased cardiac output. Reference : SRB's Manual of Surgery, 6th Edition, page no = 106.
Surgery
Trauma
e48f0783-40fc-41ca-8571-f31c3a1e8ce8
Framingham criteria for diagnosis of congestive heart failure classifies the following as major criteria except-
Extremity oedema
Acute pulmonary oedema
Paroxysmal nocturnal dyspnoes
S3 gallop
0a
multi
null
Medicine
null
ae80d5c9-2e2f-4a36-bb3a-48b61e7503ca
Investigation of choice for detection & characterization of interstitial lung disease is –
MRI
Chest X-ray
High resolution CT scan
Ventilation perfusion scan
2c
single
HRCT is the investigation of choice for interstitial lung disease.
Radiology
null
a91725e7-a8b5-4e2c-9eed-09b4529a08e8
The Tumor causing Polycythemia due to erythropoietin production is:
Cerebellar hemangioma
Medulloblastoma
Ependymoma
Oligodendroglioma
0a
single
Cerebellar hemangioma
Pathology
null
2087bcf4-9fdd-4d70-b916-05cda7b6211d
The most likely complication of insulin therapy in ketoacidosis is:
Dilutional hyponatremia
Hypoglycemia
Increased bleeding tendency
Pancreatitis
1b
single
null
Pharmacology
null
9dbd4d81-99ae-4131-8921-14c2942c26ab
The initial pharmacologic therapy of choice in this stable patient (refer to Q 87) is
Adenosine 6 mg rapid IV bolus
Verapamil 2.5 to 5 mg IV over 1 to 2 min
Diltiazem 0.25 mg /kg IV over 2 min
Digoxin 0.5 mg IV slowly
0a
single
Vagotonic maneuvers such as carotid massage or the Valsalva maneuver could ceainly be tried first. If these are unsuccessful, adenosine, with its excellent safety profile and extremely sho half-life, is the drug of choice for supraventricular tachycardia at an initial dose of 6 mg. Dosage can be repeated if necessary a...
Surgery
null
da322d1b-fa92-4479-bf66-e5f7509e7341
Eye ball movements are controlled by all of the following cranial nerves except:
Optic nerve
Abducens nerve
Trochlear nerve
Oculomotor nerve
0a
multi
Cranial Nerve I: OlfactoryArises from the olfactory epithelium.Functions solely by carrying afferent impulses for the sense of smell.Cranial Nerve II: OpticArises from the retina of the eye.Optic nerves pass through the optic canals and converge at the optic chiasm.Functions solely by carrying afferent impulses for vis...
Anatomy
null
ad20e74d-d638-4a5c-9068-89fff434d6bc
Avascular necrosis is the most common in one of the following fracture
Garden 3 and 4 fracture of femoral neck
Garden 1 and 2 fracture of femoral neck
Sub-trochanteric fracture of femoral neck
Baso-trochanteric fracture
0a
single
The Garden classification of subcapital femoral neck fractures is the most widely used. It is simple and. Garden stage III: complete fracture, incompletely displaced. femoral Garden stage IV: complete fracture, completely displaced. femoral
Orthopaedics
null
fd08f9d8-46be-42ba-b740-4f6847e27c0e
Chloride receptor defect is responsible for:
Cystic fibrosis
Wilson's disease
Alpha-1 antitrypsin deficiency
Hemochromatosis
0a
single
Ans: A (Cystic fibrosis) Ref: Harrison's 18th edn, pg 2149Explanation:Cystic FibrosisAutosomal recessiveMutation in CFTR (cysic fibrosis transmembrane conductance regulator) geneClinical FeaturesBronchiectasisExocrine pancreatic insufficiencyIntestinal dysfunctionAbnormal sweat gland functionUrogenital dysfunctionCF ai...
Medicine
Genetics
9b1f4393-9b51-456d-9476-146b1247169d
A young boy has a single scaly, hypo anaesthetic patch over Hand plus thickened ulnar nerve, diagnosis is:
Tuberculoid leprosy
Lepromatous leprosy
Indeterminate
Borderline
0a
single
Tuberculoid leprosy
Skin
null
bcb9cd4c-add4-44b4-8845-1e0b3ad8aa85
True about azathioprine is :
It has more anti tumor effect than immunosuppressant effect
It is not a prodrug
It selectively affects differentiation of T cells
It is a pyrimidine antimetabolite
2c
multi
null
Pharmacology
null
12d78741-c099-4720-b1d9-279738994e91
Tetracycline inhibits protein synthesis by-
Inhibiting initiation and causing misreading of mRNA
Binding to 30 S subunit and inhibits binding of aminoacyltRNA
Inhibiting peptidyitransferase activity
Inhibiting translocation
1b
single
Ans. is 'b' i.e., Binding to 30 S subunit and inhibits binding of ami noacyl tRNA Tetracyclineso Tetracyclines are classified into three groups -# Group 1 - Tetracycline, oxytetracycline, chlortetracycline.# Group II - Lymecycline, Demeclocycline.# Group III - Minocycline, Doxycycline.o Tetracyclines are bacteriostatic...
Pharmacology
Anti Microbial
bb233a4b-0183-4a65-ae34-4a7e98675d1a
MTAD is
Mixture of Tetracyclin, Acid and Detergent
Mixture of Triclosan Acid and Doxycycline hyclate
Mixture of Tetracyclin, Acid and EDTA
Mixture of Triclosan, Acid and EDTA
0a
single
null
Dental
null
95895b06-6bbf-43fb-8cbb-f492a645730e
A group of 8 expes discussing and interacting about a topic in front of large audience is?
Workshop
Symposium
Semin ar
Panel discussion
3d
single
- panel discussion is a group approach in health communication. - in a panel discussion, 4-8 people who are qualified to talk about a topic sit and discuss a given problem or topic in front of a large group or audience. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:865 <\p>
Social & Preventive Medicine
Health education & planning
521d1361-c99d-4bfc-aa9a-993b8e4a6385
A 28-year-old male with AIDS presents with moderate proteinuria and hypeension. Histologic sections of the kidney reveal the combination of normal-appearing glomeruli and occasional glomeruli that have deposits of hyaline material. No increased cellularity or necrosis is noted in the abnormal glomeruli. Additionally, t...
Diffuse proliferative glomerulonephritis (DPGN)
Focal segmental glomerulonephritis (FSGN)
Focal segmental glomerulosclerosis (FSGS)
Membranous glomerulopathy (MGN)
2c
multi
Focal segmental glomerulosclerosis (FSGS) is a glomerular disorder that accounts for about 10% of the cases of nephrotic syndrome. FSGS, which affects children and adults, begins as a focal process, affecting only some glomeruli. In the earliest stage, only some of the juxtamedullary glomeruli show changes. Eventually,...
Pathology
miscellaneous
3b754d8a-c4ff-4c48-9d9c-8c67df972a2d
What is the ponderal index of a child with weight 2000 g and height 50 cm –
1.6
3.6
2.2
2.6
0a
single
Ponderal index (PI) in neonate Ponderal index has been used as an indicator of fetal growth status, especially to assess assymetrical IUGR. Ponderal index can be used to indentify infants whose soft tissue mass is below normal for the stage of skeletal development. The Ponderal index is calculated by multiplying the w...
Pediatrics
null
f0afb109-b9d9-4061-9f66-01f5dfc3fca2
In Sickle cell trait patients, there is reduced risk of which of the following disease?
Typhoid
Malaria
G-6PD deficiency
Filaria
1b
single
Malaria is not seen in people sickle cell anaemia,thalassemia,G6PD deficiency disorders.Ref.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 21st edition page no 236
Social & Preventive Medicine
Communicable diseases
9f18ccee-3313-4ccf-b6d3-b1b70d6b4672
Which of the following hormones stimulates increased testosterone production by ovaries in PCOD
Estrogen
Luteinizing Hormone
Follicle - stimulating Hormone
Inhibin
1b
single
Lutenizing hormone and insulin stimulate increased testosterone production by ovaries in PCOD.
Gynaecology & Obstetrics
null
cc9c6e52-2b9c-4a28-8190-c6cbb644776f
Movements of supination & pronation take place at all of the following, EXCEPT?
Superior radioulnar joint
Middle radioulnar joint
Inferior radioulnar joint
Radio-carpal joint
3d
multi
Radio-carpal joint: Aiculation between the radius and the radioulnar disc (triangular fibrocailage complex) with the proximal row of carpal bones (scaphoid, lunate, and triquetrum). Motions present at radio carpal joint include flexion, extension, abduction and adduction. Movement of supination and pronation does not t...
Anatomy
null
c76efd0e-e890-46fd-9244-e812f2c04670
In obstruction of second pa of axillay aery, the anostomosis between the following aery will maintain the blood supply of upper limb?
Deep branch of transverse cervical aery & subscapular aery
Anterior & posterior circumflex humeral
Posterior circumflex humeral & circumflex scapular aery
Suprascapular & anterior circumflex humeral aery
0a
single
Formed by branches of- Subclan aery - first pa - Suprascapular aery - Deep branch of transverse cervical aery Axillary aery - third pa - Subscapular aery & its circumflex scapular branch There are other smaller anastomoses over the acromion process, which also helps to maintain .flow to arm. (BDC Vol I, 4/e, p 82) Anas...
Anatomy
null
d036d499-99ab-45f0-a899-419636ee49d6
Botulism causes:
Descending flaccid paralysis
Descending spastic paralysis
Ascending paralysis
Ascending spastic paralysis
0a
single
Ans. is 'a' i.e., Descending flaccid paralysis (Ref: Harrison, 18th/e, 1201)* Botulism causes acute descending paralysis of flaccid type (Areflexia).
Microbiology
Bacteria
de9ee238-6ea2-499f-8169-1226d1d5659e
In hemochromatosis iron not deposited in ?
Hea
Pituitary
Testis
Skin
2c
single
Ans. is 'c' i.e., Testis In hemochromatosis, hypogonadism is caused by impairment of hypothalamic pituitary function and not due to deposition of Iron in the Testis. Hemochromatosis Hemochromatosis is characterized by the excessive accumulation of body iron, most of which is deposited in parenchymal organs such as live...
Pathology
null