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135
4ac2aa8b-02c4-494e-90dd-aeb859abca48
1.5 mL of a solution containing 20 mg/mL of Evans blue dye is injected into plasma, the final concentration of the dye is 0.015 mg/mL, the volume of the plasma is:
1 L
2 L
3 L
4 L
1b
single
Volume of plasma = volume of dye injected / final concentration of the dye Volume of dye injected = 1.5 * 20 = 30 mg Volume of plasma = 30/0.015 = 2000 mL
Physiology
Body fluid compaments
dcd5aa7c-dfcf-4727-acf0-13de51421ca1
Chloride shift is due to
Generationof HCO3 in RBC's
Metabolism of glucoses in RBC's
Formation of O2-Hb complex in RBC's
Release of K in RBC's
0a
single
Chloride shift (also known as the Hamburger phenomenon or lineas phenomenon, named after Haog Jakob Hamburger) is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate (HCO3-) and chloride (Cl-) across the membrane of red blood cells (RBCs Ref: guyton and hall textbook of medical p...
Physiology
Respiratory system
07950cce-6d72-4405-82ba-5ba894190ae5
Pityriasis versicolor is caused by-
E. floccosum
M. gypseum
M. furfur
T. tonsurans
2c
single
Tinea Versicolor or Pityriasis Versicolor: It is a chronic recurrent condition involving stratum corneum of skin, caused by a lipophilic fungus - Malassezia furfur. Malassezia furfur is a lipophilic fungus that is found on skin. Clinical manifestation: Characterized by scaly patches of hypo to hyper pigmentation of ski...
Microbiology
Mycology
085d2cd8-530c-4424-8769-d8a9dc02da3e
Greenish colour in a contussion is due to :
Hemosiderin
Haemotoidin
Bilirubin
Biliverdin
1b
single
B i.e. Haematoidin
Forensic Medicine
null
013b2aed-5b9d-4805-a941-5781987f5667
Most commonly involved ossicle in CSOM is
Malleus
Incus
Stapes
All the above
1b
multi
Ossicular necrosis is one of the sequale of CSOM. Most commonly, long process of incus gets necrosed. Sometimes, stapes superstructure also gets necrosed. This increases the conductive hearing loss to more than 50 dB Ref: Diseases of ENT by Dhingra 6th edition Pgno : 73
ENT
Ear
06581457-c9f1-4a3f-aa65-91b9e748bc97
Superior intercostal aery is a branch of
Costocervical trunk
Dorsal scapular aery
Thyrocervical trunk
Internal thoracic aery
0a
single
Superior intercostal arery is a branch of costocervical trunk of subclan aery. BD chaurasia's human anatomy.6th edition volume 1.page no 219.
Anatomy
Thorax
552d9589-aab5-4c17-a860-4f62dc7cee75
The amniotic membrane is characterized by all the following Except
Provides maximum tensile strength
Highly vascular
It developed after 2-7 days of gestation
Derived from Foetal ectoderm
1b
multi
AMNIONAt term, amnion is tough and tenacious.It provides almost all of the tensile strength of the fetal membranes.It is avascular and pliable.It is the innermost fetal membrane and is contiguous with the amniotic fluid.
Microbiology
All India exam
9684cda6-e729-4a81-aa79-d4e86d9c678f
All of the following species of borrelia are associated with tick borne relapsing fever, except -
Borrelia recurrentis
Borrelia hermsii
Borrelia turicatae
Borrelia duttani
0a
multi
null
Microbiology
null
96b76788-5c54-47e5-aafa-7a8231e76357
In the treatment of severe bradycardia, all of the following can be the best modality of treatment except
Atropine
Pacing
Isoproterenol
Diltiazem
3d
multi
null
Medicine
null
40f39443-a88f-4798-91e9-cd706d2c9e94
Keratan sulfate I and II is found in
Cornea
Cartilage
Loose connective tissue
All of the above
3d
multi
Biologically Important GAGs:
Biochemistry
null
fa13c6bf-dbf6-42d8-9cf3-9c26d7a33258
Tetralogy of Fallot's present with one of the following:
Cenral cyanosis with clubbing
Cardiomegaly
Left ventricular hypertrophy
Normal ECG and Chest x-ray
0a
multi
Ans. is 'a' i.e. . Central cyanosis with clubbing. TOF is the commonest cyanotic congenital* heart disease in children above the age of 2 years.The four constituents of Tetralogy are :Ventricular septal defect*Pulmonic stenosis*Overriding of dextroposed Aorta *Right ventricular hypertrophy *Physiologically the pulmonar...
Pediatrics
Cyanotic Congenital Heart Disease
e22acf59-7d54-4a8a-9487-b8c9b561c531
Ferning of cervical mucus depends upon:
LH
FSH
Progesterone
Estrogen
3d
single
The Ferning of the cervical mucus is because of the high estrogen content and its DOES NOT diagnose ovulation. Maximum before ovulation and once ovulation happens, the ferning actually reduces and finally disappears due to the high progesterone. This implies that loss of ferning pattern is suggestive of ovulation. Due ...
Gynaecology & Obstetrics
Tests of Ovulation
7c2fb41c-b231-4696-8fbe-a9d2f1d28aac
Neurotransmitter depleted in Parkinson's disease:September 2007
Dopamine
Acetylcholine
Glutamate
GABA
0a
single
Ans. A: DopamineParkinson's disease has both hypokinetic and hyperkinetic features. In this condition, which was originally described by James Parkinson and is named for him, the nigrostriatal dopaminergic neurons degenerate. The fibers to the putamen are most severely affected.Dopaminergic neurons and dopamine recepto...
Physiology
null
90eceaa9-ead0-464b-9b4c-0e81fb134c3e
Dangerous area of scalp is ?
Superficial fascia
Loose areolar tissue
Pericranium
Aponeurosis
1b
single
Ans. is 'b' i.e., Loose areolar tissueThe scalp consists of five layers:SkinClose network of connective tissue (superficial fascia)Aponeurosis (galea aponeurotica) with occipitofrontalis musclesLoose areolar (subaponeurotic) tissuePericranium (outer periosteum of skull)First three layers are intimately connected and mo...
Anatomy
null
a0d9e728-a0c5-42e3-8252-94ae52b086b5
A rickshaw tyre passed on a 8 year old child. Tyre marks were found on the body. This is an exmaple of:
Percolated bruise
Imprint abrasion
Contusion
Patterned bruise
1b
single
Ans is 'b' i.e. Imprint abrasion Real confusion in this question is between imprint abrasion and patterned bruising. In both imprint abrasion and patterned brusing there is mark or pattern of the object causing injury.* Abrasion is caused by friction and/or pressure between the skin and some rough object or surface. Fo...
Forensic Medicine
Death and Investigations
b6cdede5-20e8-4d9d-b26b-c834e5824ff7
What is present in the part of the bone which received radiotherapy -
Response to radiotherapy is good
Fast healing
More destruction of bone
Tumour regression is not affected
2c
single
Infection and radiation, both cause bone destruction and predispose to pathological fracture.
Pathology
null
f3b6d8cc-1a23-4b27-9405-443f6008ec27
Beta hemihydrate particles absorb
more water
less water
no water
none of the above
0a
multi
null
Dental
null
dd830ca3-24d8-4df7-8c5e-489133b469de
Malate shuttle is important in ________
Glycolysis only
Glycogenolysis
Glycolysis and gluconeogenesis
Glycogen synthesis
2c
single
NADH cannot penetrate the mitochondrial membrane, but it is produced continuously in the cytosol by 3-phosphoglyceraldehyde dehydrogenase, an enzyme in the glycolysis sequence. The transfer of reducing equivalents is carried out by using the various shuttle systems. Malate shuttle system is of more universal utility. U...
Biochemistry
null
1bf7d4f6-d23b-496c-98dc-31736d6e9623
Narrowest part of the urethra is-
External meatus
Membranous urethra
Bulbous urethra
Internal meatus
0a
single
null
Surgery
null
e973b652-7fda-49d7-9b4f-de37b1b06eb6
Programmed cell death is known as-
Cytolysis
Apoptosis
Necrosis
Proptosis
1b
single
Ans. is 'b' i.e., Apoptosis o Programmed cell death is apoptosis. o But remember this impoant fact that not all apoptosis are programmed cell death (read text below) Apoptosis o Apoptosis is pathway of cell death that is induced by a tightly regulated intracellular program in which cell destined to die activate enzymes...
Pathology
null
b67de6a6-5153-4ab4-b004-d3232f31b23a
All of the following are decreased in Nephrotic syndrome except :
Transferrin
Ceruloplasmin
Albumin
Fibrinogen
3d
multi
Answer is D (Fibrinogen): Nephrotic syndrome is characteristically associated with increased fibrinogen levels Nephrotic syndrome is characteristically associated with increased fibrinogen levels - Hyper fibrinogenemia. This is due to increase hepatic synthesis, impaired fibrinolysis, and increased platelet aggregabili...
Medicine
null
6d6bf4f5-725f-4a95-a785-2bd6ac94eb4f
Which of the following does not occur in a patient with gastrinoma -
Epigastric pain
Diarrhoea
Basal acid output (BAO) less than 15 mEq/litre
Serum gastrin levels >200 pg/ml
2c
single
Laboratory Studies in gastrinoma Due to the elusive nature of the neoplasm, the diagnosis is based on the following 3 criteria: Fasting hypergastrinemia is present (>150 pg/mL with levels >100,000 pg/mL in some patients; a serum gastrin level >1,000 pg/mL in the appropriate clinical setting is viually diagnostic of Zol...
Medicine
Endocrinology
0d266096-61c5-4609-8e16-19db23cd4323
A school teacher gives consent for treating a child who becomes sick during a picnic away from home town. This type of consent is known as?
Paternalism
Loco Parentis
Vicarious liability
Novus Actus Interveniens
1b
single
Loco Parentis: In an emergency involving children, when parents or guardians are not available, consent is taken from the person in charge of the child. Paternalism: Is an abuse of medical knowledge so as to disto the doctor-patient relationship in such a way that the patient is deprived of his autonomy, or his ability...
Forensic Medicine
null
88713cee-71e1-494d-aad9-f442908a5963
The "water act" passed in 1974 deals with:
Provision of adequate drinking water
Prevention of water pollution
Provision of adequate irrigation water
Provision for digging of wells
1b
single
The Act provides for the creation of the Central Pollution Control Board and State Pollution Control Boards. The main function of the Central Board is to promote cleanliness of streams and wells in the States. It also provides ceain functions in the nature of advice, planning, co-ordination, publications, education and...
Social & Preventive Medicine
null
4f520708-420d-4ed9-bdae-0c9f0ee2facf
A 80 year old patient presents with a midline tumor of the lower jaw, involving the alveolar margin. He is endentulous. Rx of choice is :
Hemimandibulectomy
Commando operation
Segmental mandiblectomy
Marginal mandibulectomy
2c
single
Ans. is 'c' i.e., Segmented mandibulectomy The best t/t for such tumor is excision of the growth along with segmental mandibulectomy. Hemimandibulectomy would not be useful, as the tumor is midline. Since the bone is involved by the growth, marginal mandibulectomy would not be a good choice.
Surgery
null
2df5982b-e379-4dad-9518-6527a403f504
Ca Breast stage I and II managed by -a) Total mastectomyb) Modified radical mastectomyc) Lumpectomy and axillary clearanced) Lumpectomy, axillary clearance and radiotherapy
c
d
bd
ac
2c
single
null
Surgery
null
24e64e1a-15b0-4a9b-8ed0-1411b5cd02b2
Modern monitors to measure ETCO2 make use of
Infrared absorption spectroscopy
Ultra violet rays
Laser technology
Scatter technology
0a
single
Measurements of variations in the respiratory cycle of expired carbon dioxide by displayed waveform and by absolute numerical values is defined as Capnography and Capnometry respectivelyMeasurement of the exhaled CO2 at the level of upper airway at the end of expiration (when CO2 is at its maximum) is referred to as 3e...
Anaesthesia
All India exam
dd45c6b2-527b-4dbb-8cf4-afafe78a8da3
Flag sign is seen in ___________
Marasmus
Kwashiorkor
Vitamin A deficiency
Rickets
1b
single
In kwashiorkor, the hair is straight and hypopigmented. The length of hair that grows during the period of nutritional deprivation appears reddish brown. During the phases of better nutrition, the growing pa of hair gets appropriately pigmented. This gives the appearance of alternate bands of hypopigmented and normally...
Pediatrics
Nutrition
d8084c92-f2b5-46e3-9ae7-01019d1a371a
A 30-year-old patient presented with features of acute meningoencephalitis in the casualty. His CSF on wet mount microscopy revealed motile unicellular microorganisms. The most likely organism is
Naegleria fowleri
Acanthamoeba castellan
Entamoeba histolytica
Trypanosoma cruzi
0a
single
(A) Naegleria fowleri # The clinical syndrome associate a with N. fowleri infection is Primary 'amoebic' meningoencephalitis (RAM).> When naegleria are suspected they can be identified by their Motility in wet preparation.> Acute meningoencephalitis which can be caused by either Naegleria or Acanthamoeba. (Entamoeba hi...
Microbiology
Misc.
c6f79b25-1462-49fd-98b7-5a9213befecb
The left subclan aery is a branch of :
Bracheocephalic trunk
Ascending aoa
Arch of aoa
Left common carotid
2c
single
C i.e. Arch of aoa
Anatomy
null
1285d99f-16cb-4666-a242-3ad21d2fb19a
Kamli Rani 75 yrs old woman present with post myocardial infarction after 6 weeks with mild CHF. He had a history of neck surgery for parathyroid adenoma 5 years ago. EKG shows slow arial fibrillation. Serum Ca+213.0 mg/L and urinary Ca+2 is 300 mg/24h. On examination a small mass is felt in the para tracheal position....
Repeat neck surgery
Treatment with technetium - 99
Observation and repeat serum Ca+2 in two months
Ultrasound - guided injection of alcohol injection into the mass
3d
multi
The patient in the question is not a good candidate for surgical removal of parathyroid mass due to the underlying medical complications, so ultrasound guided alcohol injection is the most appropriate treatment. Ultrasound guided alcohol injection of the mass is used as an alternate therapy for patients with primary hy...
Surgery
null
5c9c6bba-8e74-4f55-8e86-60d5b185e6d1
Monocomponent insulin has all the following advantages except:
Can be used in pregnancy
Less hypoglycemic episodes
Longer duration of action
Less chances of lipodystrophy
2c
multi
null
Pharmacology
null
02c0d7b8-ed9d-40a1-a8a7-0c8501d067a9
The chromosomal complement of a primary oocyte is :
23X
23Y
44XX
44XY
2c
single
44XX
Gynaecology & Obstetrics
null
ade1f143-ad15-4c35-8105-3edaab41698c
Hypocalcemia in child -All except?
Digeorge syndrome
Hypo parathyroidism
Magnesium deficiency
All of above
3d
multi
Ans. is 'd' i.e., All of above Causes of hypocakemia Hypo parathyroidism Digeorge syndrome PTH receptor defect (pseudo hypoparathyroidism) Magnesium dificiency Exogenous organic phosphate excess Vit D difeciency
Pediatrics
null
a637aad7-9b7a-474a-9c44-8c190f1b65dd
For development of alveolar PO2 of 60 mm Hg and high altitude illness to develop in an otherwise healthy person from sea level, rapid ascent to following height is required
2,000 meters
3,000 meters
4,000 meters
5,000 meters
1b
single
People have different susceptible to altitude sickness,on an average it begins around 2000 to 3000 meters above sea level Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:375,376
Physiology
General physiology
f9746be0-3269-4d86-b3ac-61f03ca9becd
Drug causing decrease in late sodium current -
Nicorandil
Ranolazine
Trimetazidine
Molsidominc
1b
single
Ans. is 'b' i.e., Ranolazine o Ranolazine was initially assigned as paial fatty acid oxidation inhibitors. However, now it is believed that it acts by a different mechanism. It acts by blocking a late sodium current that facilitates calcium NCX (Sodium -Calcium exchanger) -4 Calcium overload and decrease left ventricul...
Pharmacology
null
c926d94b-bb65-429f-8d3f-d8444886ca29
Human papillomatosis is caused by?
INV
HPV
HIV
HBV
1b
single
Ans. is b i.e., HPV Human upper respiratory papillomatosis is due to infection with human papilloma virus (HPV) type 6 and 11.
Microbiology
null
8f6d874e-c8f0-418d-90b3-ca927a6881b3
By the Factory Act the age for the child to work should minimum be (in years)
14
16
18
21
0a
single
Ans. a (14). (Ref. Park, PSM, 17th/pg.586)According to the Factory Act children below the age of 14 years should not work.FACTORY ACT- 1948Applicable towhole India except Jammu & Kashmir.Scope# Establishment >10 workers where power is used and > 20 where power is not used.# Minimum 500 Cu.ft of space for each worker.# ...
Social & Preventive Medicine
Occupational Health
251391b6-c2be-4fc5-84c5-4c91b8b87b98
In organophosphorous poisoning, following are seen except:
Pupillary dilatation
Salivation
Bronchospasm
Sweating
0a
multi
A i.e. Pupillary dilation
Forensic Medicine
null
054d84b0-3ec2-4e1b-bc82-0fdbba5d8f09
Epitheloid granuloma consists mainly of which type of cells:
B cells
T cells
Monocytes
Macrophages
3d
single
Ans. D: Macrophages Macrophages/ histiocytes are the cells that define a granuloma. They often, but not invariably, fuse to form multinucleated giant cells. The macrophages in granulomas are often referred to as "epithelioid". Epithelioid macrophages differ from ordinary macrophages in that they have elongated nuclei t...
Pathology
null
24a37e56-9916-46f9-837e-4c8f77395d7e
Which of the following drugs causes extra pyramidal symptoms:
Antibiotics
Salicylates
Barbiturates
Phenothiazines
3d
single
null
Pharmacology
null
a9e47fdc-a237-467f-9afb-e21d1bc0268c
Nexus criteria in trauma is used for
Intubation
Burns resuscitation
Blood transfusion
Taking X-Ray cervical spine
0a
single
Ref: ALTS, 10th edition Pgno: 140
Surgery
Trauma
0998ed0f-df83-4d57-a226-68bc0f6ff9e3
Lower first molar has which of the following occlusal shapes
Pentagonal
Trapezoid
Rectangular
Any of the above
3d
multi
In previous question only one has to be selected so answer should be Pentagonal. But other occlusal forms are also found in lower first molar.
Dental
null
c3b039c0-4438-4c88-8bbb-82ef732a6408
Which of following lesion shows characteristic anagen, catagen, telogen phase:
Kerato acanthoma.
Basal cell carcinoma
Leukoplakia
Squamous cell carcinoma
0a
single
null
Pathology
null
e7017f0e-b7db-4907-b861-96c34df44236
The efficacy of the moist heat sterilization technique commonly used to sterilize laboratory ware and culture media is tested by using (OR) Sterilisation control for moist heat is
using Bacillus stearothermophilus
using non-pathogenic strain of clostridium tetani
using chemical indicator
using methylene blue
0a
single
null
Microbiology
null
16b38f91-7f5d-4290-9a84-9846d6448d71
"Barefoot Doctors" were from which type of medicine?
Mesopotamian Medicine
Greek Medicine
Indian Medicine
Chinese Medicine
3d
single
Barefoot doctors are farmers who received minimal basic medical and paramedical training and worked in rural villages in China. Their purpose was to bring health care to rural areas where urban-trained doctors would not settle.
Social & Preventive Medicine
Concept of health and disease
cc49ce75-c23e-47ac-87a8-08333e6739dd
Oxygenated blood is carried to the fetus by?
Umbilical aery
Umbilical vein
Ductus venosus
Hypogastric aery
1b
single
- Umbilical vein -> carries oxygenated, nutrient rich blood from placenta to fetus - Umbilical aeries -> carries deoxygenated blood from fetus to placenta for oxygenation - Ductus venosus -> shunt that allows oxygenated blood from umbilical veins directly into inferior vena cava - Hypogastric aery -> aka internal iliac...
Pediatrics
Fetal circulation
b1987595-4144-4f57-b457-46b01476edd9
The earliest sign of iron deficiency anaemia-
Increase in iron binding capacity
Decrease in serum ferritin level
Decrease in serum iron level
All the above
1b
multi
The first stage in the development of iron deficiency anaemia is the depletion of storage iron. The iron reserves are lost without compromise of iron supply for erythropoesis.Therefore the earliest sign is decreased serum ferritin level indicating poor tissue iron stores. Reference : Harsh Mohan textbook of pathology, ...
Pathology
Haematology
383a259b-7fd7-4a36-8222-3001caf9d33e
A 63-year-old man undergoes a paial gastrectomy with Billroth II reconstruction for intractable peptic ulcer disease. He presents several months postoperatively with a megaloblastic anemia. Which of the following is the best treatment for this surgical complication?
Transfusion with 1 unit of packed red blood cells
Oral iron supplementation
Oral vitamin B12 supplementation
Intravenous vitamin B12 (cyanocobalamin) supplementation
3d
single
Either megaloblastic anemia due to vitamin B12 deficiency (due to lack of intrinsic factor, which is necessary for B12 absorption and is normally produced by the parietal cells of the stomach) or microcytic anemia due to iron deficiency (due to decreased iron intake and impaired absorption in the duodenum) can result a...
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
a41a62f3-ee4a-4542-b245-f41f75803c9a
Gold standard procedure to reduce recurrence of pterygium after surgical excision is
Thiotepa
B- radiation
Conjunctival autograft
Amniotic membrane grafting
3d
single
Gold standard procedure to reduce recurrence of pterygium after surgical excision is amniotic membrane grafting.
Ophthalmology
null
2f9d5f5e-4e5d-43c7-9590-28c3acb8d14c
A 40 yr female progressive dyspnoea from 1 yr. She also has b/I bibasilar end inspiratpory crepitation.True statement are :a) May be assocated with connective tissue diseaseb) Residual volume ↑edc) ↑ Total Lung Capacityd) HRCT is useful diagontic teste) FEV1 1/FVC ratio ↑ed
acd
ade
abd
ad
1b
multi
null
Medicine
null
dfc453a3-d256-4456-8aa3-00fc6f3d9734
who gave the concept of id pa of mind
bleuler
lorenz
erikson
freud
3d
single
CONTRIBUTIONS OF FREUD o Father of psychoanalysis He founded a type of psychotherapy called psychoanalysis. It is nothing but analyzing the psych(MIND) o Interpretation of dreams According to Freud dreams are royal road to unconscious In dreams several conflicts that are present in the unconscious comes to the consciou...
Anatomy
Treatment in psychiatry
177662c9-147a-4ee6-8197-7fb9d87e5a52
Cross-product ratio is estimated by ?
Coho study
Case-control study
Cross sectional study
Field trial
1b
single
Ans. is 'b' i.e., Case-control studyOdds - ratio (cross product ratio)From a case control study odds ratio can be derived which a measure of the strength of association between risk factor and outcome.Odds ratio is closely related to relative risk (which is analysed in coho study) 4 odds ratio represents only an estima...
Social & Preventive Medicine
null
9708fa92-9600-4bc0-bfcd-e0f52e05d581
A 25-year-old man presents with a blue right arm with absent radial pulse and painful passive finger extension following a supracondylar fracture of humerus. He is suffering from:
Sudeck's atrophy
Median nerve injury
Compartment syndrome
Myositis ossificans
2c
single
Ans. C. Compartment syndromeFracture can lead to ischemia in the distal limb by direct injury to the blood vessel or by the effect of oedema increasing the pressure within the osteo fascial compartment which limits perfusion. In compartment syndrome, the increased pressure can lead to profound ischemia with necrosis of...
Orthopaedics
Injuries Around Arm & Elbow
13719463-2a2d-4187-b241-ddab72377579
Baholin gland is related to vagina
Lateral wall
Posterior wall
Anterior wall
Superior wall
0a
multi
The Baholin's glands are two pea-sized compound racemose gland located slightly posterior and to the left and right of the opening of the vagina. They secrete mucus to lubricate the vagina and are homologous to bulbourethral gland in males. ref - BDC 6e vol2 pg394
Anatomy
Abdomen and pelvis
679648de-22bb-4459-a23d-d1ee6042ee33
A diabetic patient has black necrotic mass in nose, most likely causes is:
Mucormycosis
Aspergillus
Histoplasmosis
Candidiasis
0a
single
Ans. is 'a' i.e.Mucormycosis Mucormycosis is a fungal infection of nose and paranasal sinuses which may prove rapidly fatal if untreated.lt is seen in uncontrolled diabetes or in those taking immunosuppressive drugs.Treatment is by amphotericin B* and surgical debridement.Remember :Most common fungal infection of nose ...
ENT
Nose and PNS
35399572-4e81-45f5-8087-becbe709bd9b
An African presented with itching with rashes and inguinal lymph nodes. Skin snips shows microfilariae which are non-sheathed. The most probable organism will be:
Wuchereria bancrofti
Brugia malayi
Brugia timori
Mansonella streptocerca
3d
single
Mansonella streptocerca is transmitted by biting midges. The major clinical manifestations involve the skin and include pruritus, papular rashes, and pigmentation changes. Many infected individuals have inguinal adenopathy, although most are asymptomatic. The diagnosis is made by detection of the characteristic microfi...
Microbiology
null
071e2a09-46b7-484c-a4b3-bc222a2473b4
What is the most common loss of sense above 70 years?
Proprioception
Vibration
Touch
Pressure
1b
multi
(B) Vibration > Vibration sense is the most common to be lost in old age.
Medicine
Miscellaneous
a4aaf751-b12b-4645-afa8-cb610341610a
Clergyman's knee involves ?
Olecranon bursa
Suprapatellar bursa
Infrapatellar bursa
Prepatellar bursa
2c
single
Ans. is 'c' i.e., lnfrapatellar bursa
Surgery
null
d7c1bd66-22e1-434d-8acd-ef0d57b2c94b
A drug with plasma half life of 12 hours is administered twice a day. A drug with plasma half life of 12 hours is administered twice a day. Steady state plasma concentration reached is 300 mg/dl. Which of the following statements about this drug is not true?
Plasma concentration will be approximately 260 mg/d1 after three half lives of initiation of therapy
Intravenous administration will always achieve a higher concentration than oral route
After changing the dose, plasma concentration should be measured after 3 days
Doubling the dose, will double the plasma concentration after 3 days
1b
multi
Ans. is 'b' i.e., Intravenous administration will always achieve a higher concentration than oral route
Pharmacology
null
23c4d556-4f92-408f-b2fc-c15ad2dec7d2
Laminated concretions of calcium and proteins are -
Schaumann's bodies
Ferrugenious bodies
Asteroid bodies
Gamm Gandy bodies
0a
single
Ref:Textbook of pathology (Harsh mohan) 6th edition,page no.165 Schaumann's bodies or conchoid (conch like) bodies which are concentric laminations of calcium and of iron salts, complexed with proteins.The giant cells in sarcoid granulomas contain ceain cytoplasmic inclusions Schaumann's bodies is one of them others ar...
Pathology
Respiratory system
89449b3f-aee9-4894-a02e-125138c9a4c4
Mrs. X, 25years old with a history of 2 previous pregnancies, and now 28weeks of gestation her gravidity is
Nulligravida
G1
G2
G3
3d
single
Nulligravida: a woman who currently is not pregnant and has never been pregnant.Gravida: a woman who currently is pregnant or has been in the past, irrespective of the pregnancy outcome. With the establishment of the first pregnancy, she becomes a primigravida, and with successive pregnancies, a multigravida.Reference:...
Gynaecology & Obstetrics
General obstetrics
e75f8b1b-0b43-426a-ab4f-8b2e929f61af
Lovibond angle is:
Angle between the iris and cornea
Angle between the long axis of the forearm and the long axis of upper arm
Angle between nail bed and proximal nail fold
Angle between manubrium sternum and body of sternum
2c
single
Lovibond angle or Hyponychial angle - Angle between nail bed and proximal nail fold - Normally around 1600. - It is >1800 in digital clubbing. It is described as a 'profile sign'
Medicine
Thromboembolism and Fat Embolism Syndrome
3e931d42-8759-434b-8b86-f281385258ef
Which of the following is a Rave drug?
Cocaine
Methamphetamine
Heroin
Cannabis
1b
single
Rave drugs are used for recreational purpose in parties. Methamphetamine, LSD and Ketamine are the important Rave drugs.
Psychiatry
null
bd9bb4f2-a1ee-4c33-ae83-b61839b5aba0
Triangle of koch is made by:
Posterior leaf-let of mitral valve
Coronary sinus opening
Superior vena cava opening
All
1b
multi
B i.e. Coronary sinus opening
Anatomy
null
44023f26-f6dd-442a-925e-533516a48f21
Density of cells in adult corneal endothelium is
2000 cells/mm2
3000 cells/mm2
4000 cells/mm2
5000 cells/mm2
1b
single
(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 95 - 96)The cell density of corneal endothelium is around 3000 cells/mm2 in young adults, which decreases with the advancing age
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
e29d373b-df8d-46a8-ab11-d147e11951f8
The National Population Policy 2001 aims to achieve net reproduction rate of 1 by the year ?
2005
2010
2015
2050
1b
single
Ans. is 'b' i.e., 2010 Objectives of National Population Policy 2000 Immediate objectives: To meet unmet need of contraception; to strengthen health infrastructure; to strengthen health personnel and to promote integrated service delivery for basic RCH care Mid term objective: 'To bring the total feility rate (TFR) to ...
Social & Preventive Medicine
null
3cc1adf3-c93d-4e18-89be-f5fda9538650
Serum marker to return to normal level, last in myocardial infarction is:
Lactate dehydrogenase
Creatine phosphokinase
Aspaate transmainase
Myoglobin
0a
single
Enzymes in MILDH is the last enzyme to rise (3-4 days) and also the last enzyme to return to normal level in MI (10-15 days)CPK returns to normal by 2-3 daysAST/ SCOT returns to normal by 4-5 daysMyoglobin returns to normal by 20-25 hours
Biochemistry
null
1ad6eeb6-c907-4039-9a46-cf93d8135a95
A 55-year-old male presented with painless terminal hematuria. Cystoscopic examination revealed a solitary papillary tumor. Histopathological examination of the completely resected tumor is suggestive of grade III transitional cell carcinoma with no muscle invasion. further management of this patient is best done by
Just follow up
Intravesical chemotherapy
Intravesical BCG
Cystectomy
2c
single
null
Surgery
null
b0be109c-f8fe-437c-81cc-fb6f1a28f152
Which of the following is a new drug available to treat multi drug resistant tuberculosis?
Bedaquiline
Rifampicin
Linezolid
Cefepime
0a
single
Ans. a. Bedaquiline (Ref: Harrison 19/e p1115. 205e- 7)Two novel drugs belonging to two new antibiotic classes--the diarylquinoline bedaquiline and the nitroimidazole delamanid--have recently been approved for use in severe cases of MDR-TB by stringent regulatory authorities."Two novel drugs belonging to two new antibi...
Medicine
Bacteriology
8b5bd0c6-f20e-46ee-ad64-a306877fbb3d
A most common cause of erythema multiforme –
Herpes simplex
DM
Pityriasis rosae
Erysipelas
0a
single
Most of the cases of erythema multiforme are idiopathic, but amongst the known causes, HSV is the most important cause.
Dental
null
d655f73b-bd6c-4302-8736-1d9485c0f1a5
Berkesonian bias is a type of
Selection bias
Interviewer bias
Information bias
Recall bias
0a
multi
A special example of bias is berkesonian bias termed after doctor Joseph berkeson who recognized this problem. The bias arises because of different rates of admission to hospitals for people with different diseases (refer pgn:74 park 23 rd edition )
Social & Preventive Medicine
Epidemiology
57253b53-58aa-4528-a425-57c49dd0ead3
The daily extra calorie requirement in first trimester of pregnancy is -
50
150
350
450
2c
single
For pregnant woman the extra energy requirement is 350kcal.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-588 table no.29.
Social & Preventive Medicine
Nutrition and health
5131f7aa-e9fe-4acc-aecf-6487c8ad6fa4
Best treatment for glioblastoma multiforme:
Chemotherapy
Radiation
Excision with radiation
Stereotactic surgery
2c
single
Ans. C. Excision with radiation* These are highly infiltrative tumors, and the areas of increased T2/FLAIR signal surrounding the main tumor mass contain invading tumor cells.* Treatment involves maximal surgical resection followed by partial-field external beam radiotherapy (6000cGy in thirty 200-cGy fractions) with c...
Medicine
Oncology
7cc39d9a-9d4c-4c8e-9c1e-237b16d2854a
A patient comes to hospital with a history of sore throat, diarrhoea and sexual contact 2 weeks before. The best investigation to rule out HIV is
P24 antigen assay
ELISA
Western blot
Lymph node biopsy
0a
single
null
Medicine
null
6044e2db-f865-40bf-b3ce-6d6fdad8bebd
Pentostatin inhibits
Dihydrofolate reductose
Adenosine deaminase
Thymidylate synthase
Uridylate synthose
1b
single
Pentostatin is a purine analogue that inhibits Adenosine deaminase. It is used in cases of Hairy cell leukemia (Doc: Uadiribine).
Pharmacology
null
b7f629b4-ce73-48f0-a303-f47a94cd16ea
Alkalinization of urine is done in which of the following drug poisoning ?
Amphetamine
Morphine
Phenobarbitone
Digoxin
2c
single
null
Forensic Medicine
null
0ef4b06f-20b6-445f-90a3-6b8361155976
All of the following are true about cold sterilization except
It causes breakage of DNA without temperature rise
It includes x-rays,gamma rays and cosmic rays
It destroys spores,Vegetative cells and viruses
It is used for sterilization of catgut sutures, bone and tissue grafts
2c
multi
It destroys spores and vegetative cells but not effective against viruses.
Microbiology
null
dc9e7806-89b8-4f43-9f5b-d48a98fda67c
Drug used in irritable bowel syndrome with constipation is:
Lubiprostone
Loperamide
Alosetron
Clonidine
0a
single
Ans. (A) Lubiprostone(Ref: Katzung 11/e p1080)Lubiprostone acts by stimulating Cl- channel opening in the intestine, increasing liquid secretion in gut and decreasing transit time, therefore used for chronic constipation. It has also been approved for constipation dominant irritable bowel syndrome in women.
Pharmacology
G.I.T
86d8af81-604e-45ce-9fd0-c0ea41cf9d71
A condition, which occurs in puberty and in the absence of large amounts of supragingival plague and resulting in angular bone defects in the first molar and incisor region is called
Generalized juvenile periodontitis
Localized juvenile periodontitis
Desquamate gingivitis
Chronic periodontitis
1b
multi
null
Dental
null
b79330f5-50ac-4788-9ef0-bee9492431bc
Polychromatic lusture is seen in :
Complicated cataract
Diabetes mellitus
Post radiation cataract
Congenital cataract
0a
single
A i.e. Complicated cataract Complicated cataract (i.e. cataract secondary to some intraocular disease) may be - Anterior coical Q in anterior segmental lesions as glaucoma, acute iritis, or, - Posterior coical Q in posterior segmental lesions as uveitis, RD, pigmentary retinal dystrophy. The second type of complicated ...
Ophthalmology
null
8898c315-f99e-4e0c-bd79-e00e7699e908
ROSE questionnaire is used for
Alcohol addiction
Sex addiction
Angina assessment
DVT assessment
2c
single
The Rose Angina Questionnaire (RAQ) was developed in 1962 to detect ischemic hea pain (angina pectoris and myocardial infarction) for epidemiological field-surveys.1 Since then, the RAQ has been used in many countries to detect coronary hea disease (CHD) in epidemiological research . Ref Davidson edition23rd pg 460
Medicine
C.V.S
6c0ed82e-95dd-4f3b-8cee-54c7e5645a17
Hand foot syndrome is seen with which anticancer drug?
Cisplatin
5-fluorouracil
Methotrexate
Imatinib
1b
single
Ans. B. 5-fluorouracilHand and foot syndrome is caused by 5-fluorouracil, capecitabine, doxorubicin. Cisplatin is highly emetic and nephrotoxic drug. Methotrexate is hepatotoxic.
Pharmacology
Anti-Cancer
1635e48f-815f-4015-aa80-79ecc412e48b
Coloured halos are seen in all, except –a) Mucopurulent conjunctivitis b) Acute anterior uveitisc) Tetracyclined) Glaucoma
bc
c
ac
ad
0a
multi
Coloured halos are not seen in acute anterior uveitis and this is one of the differentiating points between acute anterior uveitis and acute angle closure glaucoma Tetracycline does not cause coloured halos. Important drugs causing coloured halos Amiodarone                                                            A...
Ophthalmology
null
adcbd52a-dd24-4b67-914a-d0a00239ce71
Uses of tumor marker are all except :
Screening of a cancer
Follow up of a cancer patient, esp. for knowing about recurrence
Confirmation of a diagnosed cancer
For monitoring the treatment of a cancer
2c
multi
Tumor markers are not specific, so, cannot be used for confirmation of diagnosis. Confirmation is done by biopsy Examples: PSA Prostate cancer Ig Multiple myeloma hCG Choriocarcinoma Calcitonin Medulaary thyroid cancer Catecholamines Pheochromocytoma CEA Colon ca, Pancreatic ca CA 15.3 Breast cancer CA 19-9 Pancreatic ...
Pathology
Etiological Factors of Neoplasia
2d915186-9fa5-4dd6-9cf1-c7812000fde7
Titration of the dose of a drug with the response can be done with which of the following routes of administration:
Sublingual
Transdermal
Inhalational
Subcutaneous
2c
single
- Titration of drug dosage can be done only with the inhalational route of administration among the given options.
Pharmacology
null
527b2ea5-0ebe-4fe1-a08c-80f1c801e7f3
Urban malaria is caused by
Anopheles culicifacies
Anopheles stephensi
Anopheles sundaicus
Anopheles flulis
1b
multi
Anopheles Mosquito There are over 55 species of anopheline mosquitoes in India causing malaria An.culicifacies - Vector of rural malaria An.stephensi - Vector of urban malaria; Breed in overhead tanks An.flutilis- Efficient vector, highly anthrophilic, breed in moving water An.sundaicus : Breed in brackish water An.dir...
Social & Preventive Medicine
Communicable diseases
bab68c3e-1a10-4807-a87c-320381df9664
Procedure to be performed in the case of arrest of after-coming head due to contracted pelvis in breech:
Craniotomy
Decapitation
Zavanelli maneuver
Cleidotomy
2c
single
Ans is c, i.e. Zavanelli maneuverRef Williams, 24/e, p 567The last rescue for entrapped fetal head in term fetus is replacement of the fetus higher into the vagina and uterus followed by cesarean delivery. This is called as Zavanelli maneuver.In preterm babies, last resort for entrapment of after-coming head of breech ...
Gynaecology & Obstetrics
Malpresentation
5eeff1eb-62ce-480a-a27f-d61cd173439d
Glanzmann thrombasthenia is due to
Decreased GpIb
Decreased GpIIb/IIa
Anti-GpIIb/IIIa antibodies
Inhibition or deficiency of ADAMTS 13
1b
single
Glanzmann thrombasthenia is an autosomal recessive disorder. There is a failure of primary platelet aggregation with ADP or collagen due to inherited deficiency of two platelets membrane glycoproteins. It is caused due to deficiency of glycoprotein IIb- IIa.
Pathology
null
afe4e0da-292c-4a81-97a7-592225c549a2
A patient with conjunctival infection, which lead to corneal perforation, was positive for Gram-negative coccoid appearance on Gram stain. Fuher investigation showed small translucent colourless organism which is oxidase positive. What could be the most probable causative organism-
Moraxella catarrhalis
Neisseria gonorrhea
Psedomonas aeruginosa
Acinetobacter actinatus
1b
multi
Ans. is 'b' i.e., Neisseria gonorrhea
Microbiology
null
6562ef6c-0e55-4e77-ac60-ee46c604fa3f
CALCULUS all are true except:
Supragingival calculus is brown in colour
Hard and gritty
Calcified from plaque
Subgingival calculus is more difficult to remove than supragingival calculus
0a
multi
null
Dental
null
0702ddb7-04ff-4b1d-874d-6b10c7b2a34a
Pseudohyponatremia can be seen in -
Multiple myeloma
Diarrhea
Vomiting
CHF
0a
single
Ans. is 'a' i.e., Multipe myeloma Causes of Hyponatremia* Pseudohyponatremia# Hyperlipidemia# Hyperproteinemia (multiple myeloma, macroglobulinemia)* Dilutional# Hyperglycemia* Hypovolemic hyponatremia : decreased total body sodium with a relatively greater increase in total body water# Heart failure# Chronic renal fai...
Medicine
Fluid & Electrolyte
01fef5d1-c5ed-4a09-a15f-d958a57b9a77
Most common parotid gland tumor is:
Warthins tumor
Mucoepidermoid carcinoma
Pleomorphic adenoma
Adenoid cystic Carcinoma
2c
single
Ans. (c) Pleomorphic adenomaRef: Bailey & Love 26th ed. / 732PLEOMORPHIC ADENOMA* Overall most common tumor of salivary gland* MC benign salivary gland tumor* MC tumor of major salivary glands* MC site is parotid tail (superficial lobe).Also Know* 2nd MC benign tumor of parotid gland: Warthin's tumor* MC malignant tumo...
Surgery
Thyroid Gland
373a5018-6446-4fba-8cf9-4248f3ac0b51
Metabolic alkalosis is seen in-
Primary mineralocoicoid excess
Deficiency of mineralocoicoid
Decreased acid excretion
Decreased base excretion
0a
single
Mineralocoicoid excess increases net acid excretion and may result in metabolic alkalosis, which may be worsened by associated K+ deficiency. ECFV expansion from salt retention causes hypeension. The kaliuresis persists because of mineralocoicoid excess and distal Na+ absorption causing enhanced K+ excretion, continued...
Medicine
Fluid and electrolytes
f065d4c4-d093-474f-bd1c-705752b59162
A 30-year-old woman complains of recent easy fatigability, bruising, and recurrent throat infections. Physical examination reveals numerous petechiae over her body and mouth. Abnormal laboratory findings include hemoglobin of 6 g/dL, WBC of 1,500/mL, and platelets of 20,000/mL. The bone marrow is hypocellular and displ...
Aplastic anemia
Iron-deficiency anemia
Megaloblastic anemia
Leukemia
0a
single
- Given features suggests the diagnosis of Aplastic anemia - Aplastic anemia is a disorder of pluripotent stem cells causing bone marrow failure resulting in hypocellular bone marrow & pancytopenia - Most cases are idiopathic. - Iron-deficiency anemia (choice B) and megaloblastic anemia (choice C) are not characterized...
Pathology
Aplastic Anemia
d578c856-e21c-42d8-85aa-c083d5ffd26a
Two most impoant test to be done in a comatose patient with blood glucose of 750mg/d1 will be:
Serum creatinine
Serum sodium
CSF examination
All
0a
multi
Answer is A (Serum creatinine) Presence of blood glucose of 750mg/d1 in a comatose patient suggests a possible diagnosis of non ketotic "hyperglycemic coma or diabetic ketoacidosis. Amongst the options provided estimation of blood pH will help establish a diagnosis of diabetic ketoacidosis while estimation of serum cre...
Medicine
null
aa2dc458-b95d-4125-a7b5-df260aba1a72
Which is not a dervative of cannabis?
Charas
Ganja
Heroin
Bhang
2c
single
Cannabis also is known as Dagga in South andCentral Africa and Hashish in Egypt as many preparations Marijuana (marihuana/mary jane/pot/weed/grass): The most commonly abused form of Cannabis is marijuana, which is dried plant material including cut leaves, flowering tops, stems, and seeds. Hashish (charas): It is dark ...
Forensic Medicine
Poisoning
00b53949-9c9a-48f4-8897-df640683fb32
Kussmaul's sign is positive in a. Restrictive cardiomyopathy b. Constrictive pericarditis c. Cardiac tamponade d. Dilated cardiomyopathy e. Pneumothorax
a,b,e
a,b
a,c,d,e
a,b,c,d,e
1b
single
Kussmaul's sign is rise in JVP with inspiration.  It is seen in constrictive pericarditis  and Restrictive cardiomyopathy.
Medicine
null
274aeedf-7b3a-46ec-955f-a1a020c0fc3a
Beheaded Scottish terrier sign is –
Spondylosis
Spondylolisthesis
Lumbar canal stenosis
Slipped disc
1b
single
Oblique view of spine displays the lamina and articular processes more clearly than the classical anteroposterior & lateral views. The shadow of the neural arch resembles that of Scottish terrier dog. Spondylolysis          → Scotty dog wearing a collar sign. Spondylolisthesis     → (i) Beheaded Scotty dog sign;      ...
Radiology
null
b588061b-fc7e-49c3-ad68-92c8ab2599ad
Giant papillary conjunctivitis is most commonly seen in:
Allergic response to MTB
Soft contact lens
Intacs
Rigid gas permeable lens
1b
multi
Giant Papillary conjunctivitis is a type of allergic inflammation affecting the superior tarsal conjunctiva Seen in soft contact lens user Etiology- d/t allergic reaction to antigens deposited on the surface of lens/prosthesis Soft hydropilic contact lens use Chronic hypoxia beneath the upper lid Mechanical irritation ...
Ophthalmology
Disorders of Conjunctiva