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135
46a7c121-014d-4cb4-a1a2-fa21ce769d66
Which of the following toxin acts by inhibiting protein synthesis?
Cholera toxin
LT of enterotoxigenic E.coli
Peusis toxin
Shiga toxin
3d
single
Shiga toxin also known as verotoxin, was first identified in a major cause of dysentry called Shigella dysentriae. Shiga toxin contains an enzymatic domain and 5 binding domains which bind to globotriaosylceramide (Gb3), a glycosphingolipid on the surface of cells and the complex is internalized. The internalized shiga...
Microbiology
null
4cdd7184-db93-47f4-9812-fbe08c253c7f
The phenomenon of cancer cells switching to glycolysis even in the presence of adequate oxygen for oxidative phosphorylation is known as:
Tyndall effect
Warburg effect
Hawthorne effect
None of the above
1b
multi
Even in the presence of ample oxygen, cancer cells shift their glucose metabolism away from the oxygen hungry, but efficient, mitochondria to glycolysis. This phenomenon, called the Warburg effect and also known as aerobic glycolysis, has been recognized for many years (indeed, Otto Warburg received the Nobel Prize for...
Biochemistry
null
c01505e1-0d53-461a-a3c2-ab24d388ee13
All of the following structures are present deep to Pterion except
Middle meningeal vein
Anterior division of middle meningeal aery
Syln Point
Temporal branch of Facial nerve
3d
multi
Structures present deep to Pterion areMiddle meningeal vein and aeryStem of lateral sulcus of brain Reference: Chourasia; 6th edition; 12th page
Anatomy
Head and neck
f673861f-998a-4808-963e-68f8f5b43324
The appropriate size of LMA for an average adult patient weighing 50 kg is:
2.5
3
4
5
2c
single
Ans. c. 4.0
Anaesthesia
null
eb967938-a6ea-4906-b74e-d10e0b08b89e
Incidence of scar rupture in a pregnant lady with previous LSCS is :
0.20%
0.50%
0.70%
0.90%
0a
single
0.20%
Gynaecology & Obstetrics
null
d2fd8dcc-ada9-4d6a-8dcb-27ed85a307e6
Capsicum seed can be confused with: NEET 14
Strychnine
Dhatura
Ricinus
Opium
1b
single
Ans. Dhatura
Forensic Medicine
null
7ec255e8-b782-4207-b83b-73f5412c309f
"Groundglass hepatocytes" are seen in which of the following viral hepatitis?
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
1b
single
Ans. b (Hepatitis B) (Ref Robbins 7th/899; TABLE 18-7)Robbins 7th/B99HBV HISTOLOGY# HBV infected hepatocytes may exhibit a cytoplasm packed with spheres and tubules of HBsAg, producing a finely granular eosinophilic cytoplasm (GROUNDGLASS HEPATOCYTES).Key Morphologic Features of Viral HepatitisAcute Hepatitis (Enlarged...
Pathology
Liver & Biliary Tract
7d86d506-ac4d-4d4d-8019-f3ca69582d42
Tumour arising from Rathke's pouch is
Meningioma
Glioma
Craniopharyngioma
Ependymoma
2c
single
Rathke's pouch develop at the roof of oral cavity from surface ectoderm to form most of pituitary . Posterior pituitary develops from diencephalon. Craniopharyngioma is a tumor that develop in the sella turcica.
Anatomy
FMGE 2017
7ee022cb-7a63-40d3-8c3d-32402187137a
All are presentation of retinoblastoma except:
Leucocoria
Squint
Cataract
Glaucoma
2c
multi
C i.e. Cataract
Ophthalmology
null
21d57ed2-7db5-41ad-9507-02c1b5f733ea
During Hysterectomy, Ureter is liable for injury at?
Where it crosses pelvic brim
Where it enters bladder wall.
Where it crosses uterine aery.
None
2c
multi
Where it crosses uterine aery REF: Novak's Gynecology chapter 5, chapter 22 "About 75% of all iatrogenic injuries to the ureter result from gynecologic procedures, most commonly abdominal hysterectomy" "Significant aerial bleeding during hysterectomy usually arises from the uterine aeries or the ovarian vessels near th...
Gynaecology & Obstetrics
null
9efaf1cd-69c3-4d88-8809-de119893c58f
Intravenous resuscitation is required in a patient with 30% burns. Which of the following will be the best choice of fluid in the first 24 hours?
Normal saline
Dextrose 5%
Ringer lactate
Whole blood
2c
single
Most commonly used fluid for resuscitation in burns is ringer lactate. Some centres use human albumin solution or fresh-frozen plasma, and some centres use hypeonic saline. Intravenous resuscitation is indicated for children with a burn greater than 10% TBSA and adults with 15% TBSA. Parkland formula is the most widely...
Surgery
null
d9d51e30-8b31-4138-97ad-73fa46c9199d
Which of the following criteria can be used to determine if a pheochromocytoma lesion is benign or malignant
Blood vessel invasion
Cannot be determined by microscopic examination
Hemorrhagic and necrosis
Nuclear pleomorphism
1b
single
Ref Robbins 8/e p1159-1161;9/e p1135 Pheochromocytoma and their related counterpas in extra adrenal sites called paraganglioma, are notorious Because the only reliable indicator of metastasis potential is the presence of distant metastasis . Very malignant appearing tumors may not metastasize and benign appearing tumor...
Anatomy
General anatomy
5cafd85f-ca1e-43ca-84af-cc03d478e531
Non cicatrical alopecia is present in-
Scleroderma
Lichen planus
Psoriasis
Parva virus
2c
single
C. i.e. Psoriasis
Skin
null
857f0b90-de63-4fbb-8864-94dea9de31bd
Time dependent Killing is exhibited by all the following drugs except:
Ceftriaxone
Vancomycin
Gentamicin
Meropenem
2c
multi
* Time dependent killing(TDK) : Here, the killing activity depends upon the length of time, plasma concentration is above MIC. It is shown by:* Beta Lactams.* Vancomycin Concentration dependent killing(CDK) : Here, killing activity depends upon the ratio of plasma concentration to MIC.It is shown by:* Aminoglycosides.*...
Pharmacology
Protein Synthesis Inhibitors
554361c6-a037-426a-a530-136b0009f1c0
Prozone phenomenon is due to-
Excess antigen
Excess antibody
Hyperimmune reaction
all
1b
multi
Ans. is 'b' i.e., Excess antibody
Microbiology
null
39534c0b-dc03-4b23-a7e3-f3f5a1695fa8
Cart wheel appearance of Tympanic membrane is seen in which stage of Asom
Stage of Tubal occlusion
Stage of Resolution
Stage of suppuration
Stage of Pre-suppuration
3d
single
null
ENT
null
31ddf634-052d-4e46-adff-ea8cc2ff6068
Rocky mountain spotted fever Cause and vector are:-
R. Akari and mite
R. Conori and tick
R. Rickettsii and tick
R. Prowazekii and louse
2c
single
RICKETTSIAL DISEASE CAUSE VECTOR RESERVOIR EPIDEMIC TYPHUS R. prowazekii Louse Man ENDEMIC TYPHUS R. typhi Flea Rodents SCRUB TYPHUS R. tsutsugamushi Trombiculid mite Rodents INDIAN TICK TYPHUS R. conori Tick Rodents RMSF R. ricketisii Tick Rodents R.POX R. akari Mite Rodents Q FEVER Coxiella - Cattle TRENCH FEVER Baon...
Social & Preventive Medicine
VBDs, Arboviral & Viral Infections, Surface Infections
683d22b2-7075-4df3-afe4-47f5f3dc1bfa
Fluid content of the blood is:
Plasma
Serum
Water
Tissue fluid
0a
single
null
Physiology
null
42d6d9d0-8c2d-4d9d-8883-f85610e59c3f
Emergency contraceptives are effective if administered within following period after unprotected intercourse:
24 hours
48 hours
72 hours
120 hours
3d
single
Ans. is d, i.e. 120 hoursRef: Shaw 15th/ed, p237; Current Concepts in Contraception and Women Death, pl05, Leon Speroff8th/ed, p1042The standard recommendation is to start emergency contraceptive not later than 72 hours. The greatest protection is offered, if it is taken within 12 hours, as postponing the dose by 12 ho...
Gynaecology & Obstetrics
Contraceptives
ea09d8bf-a5f0-4bbe-b32d-fbf0df74056a
All of the following are true regarding Temporal arteritis except
Age > 50 years
Unilateral headache
Diagnosed by measuring high ESR
Complicated by ischemic optic neuropathy
1b
multi
(B) Unilateral headache # Giant cell arteritis or Cranial arteritis or Temporal arteritis> Occurs almost exclusively in individuals > 50 years> The disease is characterized by the complex of fever, anemia, high ESR, and headaches in a patient over the age of 50 years.> A well recognized & dreaded complication of giant ...
Medicine
Miscellaneous
1d306e41-d04e-45fd-b435-41f6c07fdda1
Adequate Total per capita water for Urban domestic purposes?
50-100 Liters
100-150 Liters
150-200 Liters
200-250 Liters
2c
single
Ans. is 'c' i.e., 150-200 litresThe basic physiological requirements for drinking water have been estimated at about 2 litres per head per day.A daily supply of 150-200 litres per capita is considered as an adequate supply to meet the needs for all urban domestic purposes.
Social & Preventive Medicine
null
47c1fa8d-0ab7-41db-9250-a26de1e35027
An autoimmune disease is – a) Pemphigus vulgarisb) Psoriasisc) Lichen planusd) Acne vulgaris
abc
bc
acd
bcd
0a
single
Autoimmune skin disorders Autoimmune bullous skin disorders Pemphigus Bullous pemphigoid Dermatitis herpetiformis Lichen planus Lichen planus is believed to be an autoimmune disorder as it often occurs concurrently with other autoimmune disorders like primary biliary cirrhosis, diabetes, chronic active hepatitis. ...
Dental
null
d7efce9a-b450-4047-b4ec-6302066554f5
Aerial blood supply to Little's area is from all the following except
Sphenopalatine aery
Anterior ethmoidal aery
Superior labial aery
Posterior ethmoidal aery
3d
multi
Aeries supplying Little's area are: a. Sphenopalatine aery. b. Superior labial aery. c. Anterior ethmoidal aery. d. Septal branches of greater palatine aery.
Pathology
All India exam
a677f0a3-b6b2-42d3-908b-0c1d30c5e1ae
Ligamentum teres is the remnant of
Umbilical vein
Portal vein
Ductus venosus
Umbilical artery
0a
single
(A) Umbilical vein SOME FREQUENTLY ASKED REMNANTS* Ductus arteriosusLigamentum arteriosum* Ductus venosusLigamentum venosum* Left umbilical veinLigamentum teres of liver* Right umbilical veinDisappears* Vitello-intestinal ductMeckel's diverticulum* Wolffian ductGartner duct> After obliteration, the umbilical vein forms...
Anatomy
Misc.
8f914948-2833-44af-83b9-5356dc33fc16
Classification of aoic dissection depends upon
Cause of dissection
Level of aoa affected
Percentage of aoa affected
None
1b
multi
Aoic dissection occurs when blood splays apa the laminarplanes of the media to form a blood-filled channel within theaoic wall.The clinical manifestations of dissection depend primarily on the poion of the aoa affected; the most serious complicationsoccur with dissections involving the proximalaoa and arch.Thus, aoic d...
Pathology
Cardiovascular system
05c02e5d-2b0f-47c1-9b0f-ae85c38ee50c
True about helicobacter pylori are all except -
Urea breath test is diagnostic
Grain negative, flagellate bacilli
Risk factor for development of adenocarcinoma of stomach
It provides life long immunity
3d
multi
null
Microbiology
null
86f41989-84fe-4af8-a337-ffb783d44834
All are indications for penile angiography except:
Painful priapism
Peyronie's disease
Erectile dysfunction
Arterio-venous malformation
0a
multi
Priapism is of two types. A low-flow (ischemic), painful priapism and the other high-flow (non-ischemic), painless priapism. Penile angiography is not indicated in the painful, low-flow priapism. It is indicated for the high-flow, non-ischemic priapism which is painless. Priapism Priapism is defined as prolonged erec...
Surgery
null
1b987a0b-2fbc-407c-8ade-b8d813117243
Most impoant enzyme in DNA replication for chain elongation
Helicase
DNA polymerase I
DNA polymerase III
Topoisomerase III
2c
single
Ans. is 'c' i.e.,DNA polymerase III Impoant DNA PolymerasesIn ProkaryotesDNA polymerase I :- Helps in gap filling and synthesis between okazaki fragments of lagging strand, and replaces ribonucleotides of RNA primer by deoxyribonucleotides. It has (i) 3' 5' exonuclease activity, (ii) 5' 3' exonuclease activity and (iii...
Biochemistry
null
92635d7a-5567-4d5c-8a4b-d1825418e6bc
Which of the following is the least common site of pain in a case of rheumatoid ahritis? NOT RELATED- OHO
Cervical
Knee
Low back
Ankle
2c
single
.
Pharmacology
All India exam
62eb1fa4-d1dd-438e-aeab-b95f9053c535
Superficial perineal muscles include-
Iliococcygeus
Ischiococcygeus
Bulbospongiosus
Levator ani
2c
single
Muscles in superficial perineal space. -        Ischiocavernosus -        Bulbospongiosus -        Superficial transverse perinei
Anatomy
null
48f58d58-7c38-4402-a2f8-432e588223f1
Which anaesthetic modality is to be avoided in sickle cell disease –
General anaesthesia
Brachial plexus block
I.V. Regional Anaesthesia
Spinal
2c
single
null
Anaesthesia
null
0f9b3bd0-1cde-4f9f-ae25-453760fa3465
Commonest cause of ureteric injury during surgical operation is
Abdomino-perineal resection
Hysterectomy
Prostectomy
Colectomy
1b
single
Surgical trauma during pelvic surgery is the most common cause of ureteric trauma This occurs most often during vaginal or abdominal hysterectomy when the ureter is mistakenly divided, ligated, crushed or excised. Pre-emptive ureteric catheterisation makes it easier to identify the ureters. ( ref : Bailey 27th ed , cha...
Surgery
Urology
f55764f6-a1de-404f-8fc2-296b52fdc15f
Misoprostol is an analogue of
PGE1
PGE2
PGF2alfa
PGI2
0a
single
Misoprostal: PGE-1 Given transvaginally and orally Dose of 25 micrograms every 4 hrs is found to be more effective than PGE -2 for cervical ripening and labor induction. Oral use of misoprostal is less effective than vaginal administration . Ref: Dutta Obs 9e pg 485.
Gynaecology & Obstetrics
Abnormal labor
28c2d5a3-6cdc-4666-af70-740e64b800a6
The thickness of thin rubber dam is:
0.002 inch
0.004 inch
0.006 inch
0.2 inch
2c
single
null
Dental
null
b153349f-0c0c-4cae-863a-33177eb4abdb
Which of the following is true about seminoma?a) It is radiosensitiveb) It arises only from cryptorchid testisc) AFP is increasedd) It is chemosensitive
b
c
ad
ab
2c
multi
Seminomas are both radiosensitive & chemosensitive tumors.
Surgery
null
737a208e-0830-46e3-9056-2917b1108b2e
Radical dissection of neck includes all except -
Cervical lymph nodes
Sternocleido mastoid
Phrenic nerves
Internal jugular vein
2c
multi
null
Surgery
null
58e1a7dd-6fc3-4b0c-8195-c67ad3d198d3
Not a feature of traumatic optic neuropathy:
RAPD
Dilatation of pupil
Centrocecal scotoma
Macular edema
3d
single
Macular edema is not a characteristic feature of traumatic optic neurpathy. Traumatic Optic Neuropathy Loss of vision. Dilatation of pupil. Impaired Pupillary light reflex. Contrast sensitivity is decreased. Central or centrocecal scotoma (though less common, it can be seen in traumatic optic neuropathy) MRI is the inv...
Ophthalmology
Retina
023569d6-3a3d-41b5-8adb-8e560805adb3
Codex alimentarius is related to -
Water purity
Milk purity
Air polution
Food stardardization
3d
single
Food standards are done by CODE ALIMENTARIUS, PFA STANDARDS, THE AGMARK STANDARDS, BUREAU OF INDIA STANDARDS. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 610)
Social & Preventive Medicine
Nutrition and health
52fbc1c4-deb2-48c4-a05f-29dfd62e1ca8
Sinus not present at birth is -
Ethmoid
Maxillary
Sphenoid
Frontal
3d
single
Development and grwoth of paransal sinuses
ENT
null
5c17bf5c-dddd-4581-b557-07251975b6fd
Tillaux fracture involves:
Lower end tibia
Upper end tibia
Lower end femur
Upper end femur
0a
single
Tillaux fracture Lower tibial epiphysis injury (anterolateral pa)
Orthopaedics
Lower Limb Traumatology
90252609-b0bf-4455-9576-b318fe579e69
EEG rhythm in full awake and ale state?
Alpha
Beta
Theta
Delta
1b
single
Ans. is 'b' i.e., BetaBeta wave is seen when the person is fully awake and ale and is thinking with maximum concentration.Therefore it is also called arousal or ale response.
Physiology
null
538885ec-99dd-4e01-8c61-7416435ea194
Atractiloside act as ?
Uncoupler
Inhibitor of oxidative phosphorylation
Inhibitor of complex I of ETC
Inhibitor of complex III of ETC
1b
single
Ans. is 'b' i.e., Inhibitor of oxidative phosphorylationInhibitors of electron transpo chain?Inhibitors of respiratory chain may be divided into three groups : ?1. Inhibitors of electron transpo chain properThese inhibitors inhibit the flow of electrons through the respiratory chain. This occurs at following sites.Comp...
Biochemistry
null
e5554a36-2285-40cc-8020-554dda2f3b20
Champagne glass pelvis is seen in
Cretinism
Achandro plasia
Osteomalacia
Rickets
1b
single
(Achandroplasia): (306- Maheshwari 4th edition)Champagne - glass' pelvic cavity found in ACHONDROPLASIA(275-Aids to radiological differential diagnosis chapman)ACHONDROPLASIA(Primary defect of enchondral bone formation, Autosomal dominant (but 80% are spontaneous mutations)SkullPelvis1. Large skull, small base, small s...
Orthopaedics
Miscellaneous
88fabb45-2feb-447b-8ede-75d43494046a
Type A (augmented) adverse drug reactions are characterized by all EXCEPT:
Qualitatively abnormal responses to the drug
Predictable from the drug's known pharmacological or toxicological effects
Generally dose-dependent
Usually common
0a
multi
Predictable (Type A or Augmented) reactions - quantitatively responses- includes side effects, toxic effects and consequences of drug withdrawal. They are more common, dose-dependent and mostly preventable and reversible. Ref ; KD Tripathi pharmacology 7 th edition (page no; 82)
Pharmacology
General pharmacology
a7e9ea72-b4ac-4121-b916-f7e54de42f75
A specimen from a lung biopsy reveals occasional plexiform lesions within pulmonary aerioles. This abnormality is most characteristic of
Churg-Strauss syndrome
Adult respiratory distress syndrome
Wegener's granulomatosis
Pulmonary hypeension
3d
single
) Pulmonary vascular sclerosis refers to the vascular changes associated with pulmonary hypeension. Elevation of the mean pulmonary aerial pressure is the result of endothelial dysfunction and vascular changes. The vascular changes vary with the size of the vessel. The main aeries have atheromas that are similar to sys...
Pathology
miscellaneous
92670377-2898-492a-bd74-8c5f2190e230
Incised looking laceration is seen in all, except AFMC 11; NEET 13
Iliac crest
Zygomatic bone
Shin
Chest
3d
multi
Ans. Chest
Forensic Medicine
null
4c49f1f9-24e6-4c2d-93e4-31aa596557f2
Large placenta is seen in
Twins
Oligohydramnios
IUGR
Pre-eclamptic toxemia
0a
single
Ans. a Twins. (Ref. Dutta, Obstetrics, 4th/pg.221)D/d of Large placenta/hyperplacentosis:# Twin pregnancy# Hydrops fetalis# Diabetes in pregnancy# IUGRHUMAN PLACENTA# It is Discoid, Deciduate and Haemchorial.# It develops from--- foetal (4/5th)--chorionic frondosum and- maternal (l/5th)--decidua basalis.# Its developme...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
d361ab60-b65c-4ff9-8e58-8a85362a2ebb
Socially acquired behavior is known as: March 2005, September 2010
Culture
Socialization
Internalization
Custom
0a
multi
Ans. A: Culture Culture is defined as "learned behaviour which has been socially acquired". It is the central concept around which cultural anthropology has grown. Socialization refers to the process of inheriting norms, customs and ideologies. It may provide the individual with the skills and habits necessary for paic...
Social & Preventive Medicine
null
a2b33a49-6906-457c-9330-9926e1e5a569
Glucose diffusion in RBC by ?
GLUT I
GLUT 2
GLUT 3
GLUT 4
0a
single
Ans. is 'a' i.e., GLUT 1
Physiology
null
9815af73-704e-4c5c-a1a9-37e8ed16084c
A 58 year old woman has been diagnosed with locally advanced breast cancer and has been recommended for chemotherapy. She has five years history of myocardial infarction and congestive heart failure. Which antineoplastic drug should be best avoided?
Anthracycline
Alkylating agent
Platinum compound
Bisphosphonates
0a
multi
Ans. is 'a' i.e. AnthracyclineRef: Katzung 8th/e 937-938, Harrison 16th/e p 475 (15th/e p 434)Anthracyclines are anticancer antibiotics and they include Doxorubicin (Adriamycin) and Daunorubicin.The major toxicity of anthracyclines is potentially irreversible cumulative dose related toxicity.They may causes arrhythmias...
Pharmacology
Anti-Neoplastic Agents
dd42d061-4d03-4c68-8f0d-8f384209bb95
A 9-year-old girl child developed a 10 mm area of induration on the left forearm 72 hours after intradermal injection of 0.1 ml of purified protein derivative (PPD). Which of the following is most likely to be seen on the X-ray of this patient?
Marked hilar adenopathy
Upper lobe calcifications
No abnormal findings
Reticulo-nodular densities
2c
single
Most Mycobacterium tuberculosis infections are asymptomatic and subclinical infections. In most healthy people primary tuberculosis is asymptomatic, although it may cause fever and pleural effusion. Generally, the only evidence of infection, if any remains, is a tiny, fibrocalcific pulmonary nodule at the site of the i...
Pathology
Pulmonary Tuberculosis and Lung Abscess
fa0aad7f-16a8-4459-a7e0-1e451da8c5e3
All are seen in hypersplenism except:
Anemia
Thrombocytopenia
Splenomegaly
Hypocellular bone marrow
3d
multi
Ans. (d) Hypocellular bone marrowRef: Sabiston 19/e p 1553-1554Hypersplenism:* Spleen Enlargement+Decrease in Cell count in more than one cell line (Anemia, thrombocytopenia, leucopenia) is known as hyper splenism* Important feature on Bone marrow study is there will be Hyper plasia and immediate improvement of blood c...
Surgery
Spleen
a6fc3739-fdca-4018-aa63-9d66ed22db10
False regarding invlovement in Crohn's disease
Anorectal area
Rectum
Small intestine with Rt. colon
Large intestine alone without involvement of small intestine
1b
multi
Ans. is 'b' i.e., Rectum
Surgery
null
2018386e-1a58-495e-927f-43c2de258008
Latanoprost (PGF2 alfa) is used in -
Maintenance of ductus aeriosus
Pulmonary hypeension
Gastric mucosal protection
Glaucoma
3d
single
Ans. is 'd' i.e., Glaucoma PG F2 alpha (Latanoprost) is used in glaucoma.
Pharmacology
null
be5797c0-922f-4b84-809b-a178e4a8f0aa
The standard sutureless cataract surgery is done with phacoemulsification and foldable IOL has an incision of –
1mm–1.5mm
2mm–2.5min
3mm–3.5mm
3.5mm–4.5mm
2c
single
In phacoemulsification, the nucleus is emulsified using high frequency sound waves and then sucked out of the eye through a small (3.2 mm) incision.
Ophthalmology
null
a102e59e-6ab6-4620-8193-42395f3928f3
Following sign is diagnostic of which condition?
Peptic ulcer disease
Strawberry gallbladder
Carcinoma stomach
Patent vitellointestinal duct
2c
multi
Ans. C. Carcinoma stomacha. Ulcerating carcinoma of the stomach with mass is the most frequent type encountered in North America and Western Europe.b. These carcinomas have been described as irregular, saucer-shaped lesions with ulcerated centers.c. Such a configuration may produce the meniscus or Carman sign, which in...
Radiology
G.I.T.
466a6eec-9817-4c9d-9492-243d9895e9ad
Glaukomflecken is –
Acute uvetis due to glaucoma
Lens opacity due to glaucoma
Retinal detachment due to glaucoma
Corneal opacity due to glaucoma
1b
single
Epithelial cell necrosis leads to focal opacification of the lens epithelium as glaucomflecken in acute angle-closure glaucoma.
Ophthalmology
null
5b06347e-0194-4f80-9b78-9aa2c1ff7927
Elimination after 4 half lives in first order Kinetics is
84%
93%
80.50%
4.75%
1b
single
Ans. is 'b' i.e., 93% Half life Elimination 1t%2 50% 2t'/2 75% 3 0/2 87.5% 41 93.75% 5 t'/ 96.875
Pharmacology
null
6316b949-883e-429c-a197-f2dfffac989c
Hyperventilation in high altitude is due to
Respiratory alkalosis
Respiratory acidosis
Hypercapnea
Decreased concentration of bicarbonate
0a
single
Hyperventilation in high altitude is due to respiratory alkalosis Ref: guyton and hall textbook of medical physiology 12 edition page number:375,376,377
Physiology
Respiratory system
c1b5ea36-e9f5-4bda-8eff-8585fcee7ce2
The following regarding colostomy are true except :
A colostomy is an artificial opening made in large Bowel to divert the faeces to the exterior
Temporary colostomy is established to defunction an anastomosi
Permanent colostomy is formed after the resection of Rectum by the abdominoperinea technique
Double barreled colostomy is commonly done nowadays
3d
multi
• Bailey says “Double-barrelled colostomy was designed so that it could be closed by crushing the intervening ‘spur’ using an enterotome or a stapling device. It is rarely used now, but occasionally the colon is divided so that both ends can be brought to the surface separately, ensuring that the distal segment is comp...
Surgery
null
addb8cf1-0889-4834-86f6-c36eca89aa34
The first step in public health procedure is-
Analysis of programme
Planning of programme
Situation analysis
Appraisal of programme
2c
multi
* The steps in public health procedure are as follows- 1) Survey. 2) Situation analysis. 3) Programme planning. 4) Programme operation. 5) Financing. 6) Programme appraisal.
Surgery
null
3c1e27b5-6f86-4203-a93b-51ec27e6b8c8
A young patient is diagnosed to have choriocarcinoma the treatment of choice is :
Hysterectomy
Chemotherapy
Chemotherapy followed by hysterectomy
Hysterectomy followed by chemotherapy
1b
single
Chemotherapy
Gynaecology & Obstetrics
null
22f7e828-a48f-4e6a-a009-fe0e6a4057b7
In a family, the father has widely spaced eyes, increased facial hair and deafness. One of the three children has deafness with similar facial features. The mother is normal. Which one of the following is least likely pattern of inheritance in this case-
Autosomal dominant
Autosomal recessive
X-linked dominant
X-linked recessive
0a
single
Ans. is 'a' i.e., Autosomal dominant (most likely) o It is typical presentation of waardeburg syndrome type - 1. --> Widely spaced eyes, Hearing loss, Increased facial hair o It is an autosomal dominant disorder. o In autosomal disorder, if one parent is affected and the other is normal, 25% of children (1 out of 4) wi...
Pediatrics
null
13b5a0d4-10b0-4ce2-82f0-ca86b13e79df
Chvostek sign is?
Twitching of circumoral muscles on tapping of facial nerve
Involuntary blink on tapping on facial nerve
Inability to open eye on tapping of facial nerve
Inability to close eye on tapping of facial nerve
0a
single
1. Chvostek sign - seen in hypocalcemia - Twitching of Circumoral Muscle on tapping of Facial Nerve 2. Inability to open eye on tapping of facial nerve - L.P.S 3rd nerve
Medicine
Electrolyte Imbalance
6da9b62e-a507-43f6-8cca-138b8a8dea1d
Coho study is a type of -
Clinical trial
Analytic study
Descriptive study
Experimental study
1b
single
Ans. is 'b' i.e., Analytic study Coho study o Coho study is a type of analytic observational study (like case control study). o Coho study proceeds forward from cause to effect, i.e., disease has not occured in subjects (In contrast to case-control study which proceeds backward from effect to cause).
Social & Preventive Medicine
null
afc1f5e9-e485-4037-9844-1420226cfd3f
Lambda - Panda sign is typically seen in-
Sarcoidosis
Tuberculosis
Histoplasmosis
Leishmaniasis
0a
multi
Ans. is 'a' i.e., Sarcoidosis o Lambda sign and Panda sign on Gallium scan are typically described for sarcoidosis.o Active pulmonary and/or mediastinal sarcoidosis is gallium avid and a positive gallium scan can support the diagnosis of sarcoidosis. Typical patterns of uptake have been described as 'panda' and 'lambda...
Medicine
Interstitial Lung Disease
5e7c95c9-3327-43cb-9d31-027c90bf3c4f
COWS is related to ?
Romberg test
Caloric test
Fistula test
Hallpike positional test
1b
multi
Ans. is'b'i.e., Caloric testln bithermal caloric< test rCold water provokes nystagmus towards the opposite ear, while wann wotet grovolecs nystagmus towards sarne ear (COWS:- Cold - opposite, Warm - same).
ENT
null
46de4a8d-7024-4a47-8fa9-72ef146a3f1f
Pulmonary fibrosis is seen with :
Bleomycin
Cisplatin
Methotrexate
Actinomycin D
0a
single
Bleomycin is a marrow sparing drug but it causes pulmonary fibrosis and skin toxicity as adverse effects. Another antican­cer drug causing pulmonary fibrosis is busulfan.
Pharmacology
null
4ac2b77f-98ea-4f6e-90c4-4eb67af403b4
Phocomelia is-
Absence of long bones
Absence of brain
Reduplication of bones
Absence of hea
0a
single
Ans. is 'a' i.e., Absent long bones 'Phacomelia' o Is a term applied to a marked reduction in the size of limbs The distal pa of the limbs are placed very near the trunk (absent long bones). o Seen in foetuses of mothers who recieved thalidomide during pregnancy.
Pediatrics
null
bc773b1e-d4ae-4158-b46b-f6ff607365de
Cutaneous vasoconstriction is mediated by
Sympathetic adrenergic nerves
Sympathetic cholinergic nerves
Parasympathetic cholinergics
Somatic nerves
0a
single
Sympathetic noradrenergic division constricts the blood vessels of the skin(which limits bleeding from wounds). Ref: Ganong&;s review of medical physiology; 23rd edition; pg: 268.
Physiology
Nervous system
ae4182f7-b9b6-4546-9c59-fe432b9d8af7
Which is an indicator of severe Ulcerative colitis?
Blood in lumen on sigmoidoscopy
Stool volume >1 It
Serum albumin <40
Abdominal discomfort
0a
single
(A) Blood in lumen on sigmoidoscopy # Severe Ulcerative collitis: Bowel movements >6 per day, Severe Blood in stool, Severe Fever 37.5C mean.Tachycardia >90 mean pulse, Anemia <75%, Sedimentation rate >30 mm, Endoscopic appearance Spontaneous bleeding, ulcerations.> Sigmoidoscopy is used to assess disease activity and ...
Medicine
Miscellaneous
7d171def-9ed8-4944-8998-0b7d5325eebf
Dilator pupillae is supplied by -
Post-ganglionic parasympathetic fibers from Edinger Westphal nucleus
Post-ganglionic sympathetic fibers from cervical sympathetic chain
IIIrd nerve
Sympathetic fibers from fronto-orbital branch of V nerve
1b
single
Dilator pupillae muscle is suppliedby the postganglionic fibers arising from the cervical sympathetic chain. ... Oculomotor nerve supplies the skeletal as well as the smooth muscles of the eyeball. It carries the pre-ganglionic fibers from the Edinger-Westphal to supply two smooth muscles in the eyeball Ref AK khurana ...
Ophthalmology
Ocular motility and squint
60664f63-49fd-46ba-ba3e-de2cb0dec620
Non-depolarizing blockade is potentiated by:
Hyperkalemia
Hypomagnesemia
Chronic Phenytoin therapy
Quininidine
3d
single
Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. This is accomplished either by acting presynaptically the inhibition of acetylcholine (ACh) synthesis or release or by acting postsynaptically at the acetylcholine receptors o...
Pharmacology
Anesthesia
db6cad35-660d-4deb-80fa-d16df9b9f3e4
Refrigerated blood stored up to 48 hours before transfusion can destroy which of the following
HIV
Hepatitis B
Treponema pallidum
Plasmodium vivax
2c
multi
Treponema pallidum is killed in 1 to 3 days at 0-4degrees centigrade, so transfusion syphilis can be prevented by storing blood in the refrigerator before transfusion Stored frozen at -70deg C in 10% glycerol, or in liquid nitrogen (-130 deg C), it remains ble for 10-15 years. Ref: Textbook of microbiology; Ananthanara...
Microbiology
Bacteriology
5e76f6b5-6a5d-478e-9394-7556e3985b93
A 30-yebar old patient presented with features of acute meningoencephalitis in the casualty. His CSF on wet mount microscopy revealed motile unicellular microorganisms. The most likely organism is -
Naegleria fowleri
Acanthamoeba castellani
Entamoeba hystolytica
Trypanosoma cruzi
0a
single
Naegleria fowleri, the only pathogenic species of naegleria Human infection comes from water containing the amoebae and usually follows swimming or diving in ponds. Patients are mostly previously healthy young adults or children. The amoebae invade the nasal mucosa, pass through the olfactory nerve branches in the crib...
Microbiology
parasitology
44e81922-0b11-4350-ae6a-81f87440161c
All of the following methods are used for the diagnosis of HIV infection in a 2 months old child, except:
HIV-1 PCR
Viral culture
HIV ELISA
p24 antigen assay
2c
multi
HIV ELISA is required for detection of antibodies against the virus. The antibodies may be present in the infant because of maternal infection also because IgG antibodies can cross the placental barrier. So, this test is not reliable for diagnosis of HIV in a 2 month old child. HIV culture method is called as 'peripher...
Pathology
Immunodeficiency Disorders
e5d7dfbb-c2b1-4a3b-9826-5493a2704935
Artery of hindgut is
Coeliac trunk
Superior mesenteric
Inferior mesenteric
None
2c
multi
null
Anatomy
null
4e48e4e6-7393-487a-afbe-221b6e7a013a
Usual sign of opioid withdrawal: PGI 13
Stupor
Constipation
Constricted pupil
Yawning
3d
single
Ans. Yawning
Forensic Medicine
null
015a44de-cdf2-465f-9cd2-c26ab13b85c7
Congenital toxoplasmosis, all are true, except
Occurs in primarily infected mother during pregnancy
As gestational age increase, risk of transmission to fetus increases
Infant is usually asymptomatic, if infection is transmitted in 3rd trimester.
None of the above
3d
multi
Congenital toxoplasmosis is a disease that occurs in fetuses infected with Toxoplasma gondii, a protozoan parasite, which is transmitted from mother to fetus.  It can cause miscarriage or stillbirth.  It can also cause serious and progressive visual, hearing, motor, cognitive, and other problems in a child.  Most infec...
Microbiology
null
e2d63e36-5dee-479e-aee8-967e5e9cd04e
The reagent used in Apt test is
Sodium bicarbonate
KCL
Sodium hydroxide
Sodium chloride
2c
single
Alkali denaturation test (Apt-Downey test / apt test)Used to detect differentiate Fetal or neonatal blood from maternal blood (Qualitative).PrincipleMethodFetal hemoglobin (alpha 2 gamma 2 subunits) is resistant to alkali (basic) denaturation, whereas adult hemoglobin (alpha2 beta 2 subunits) is susceptible to such den...
Pathology
All India exam
81637a16-b0bb-41cd-90cf-de56f301b6d2
Hanging drop method is used for-
Trichomonas
Plasmodium
Toxoplasma
Cryptosporidium
0a
single
null
Microbiology
null
70b8ed66-1d24-4156-8285-19e19f9181b6
Predict the effect of aldosterone hypersecretion on body fluid pH and electrolytes ?
pH decreased, K+ decreased, Na+ increased
pH increased, K+ decreased, Na+ increased
pH decreased, K+ increased, Na+ decreased
pH increased, K+ increased, Na+ decreased
1b
single
Aldosterone increases the rate of sodium absorption and potassium secretion by the kidneys, but in high concentrations aldosterone also stimulates hydrogen ion secretion. Therefore elevated aldosterone levels such as occur in patients with Cushing's syndrome can elevate body fluid pH above normal (alkalosis). The major...
Physiology
null
98e836b0-8e07-4ef2-9cad-9bd55ba72dcc
Isovolumetric relaxation preceeds:
Ventricular ejection
Ventricular relaxation
Atrial contraction
Atrial relaxation
0a
single
Ventricular ejection
Physiology
null
759faf15-dbbf-40ab-ad95-63b62e01e51b
Saw tooth appearance in abdominal barium enema X ray is seen in
Multiple polyposis
Ischemic colitis
Diveiculosis
Ulcerative colitis
2c
single
Diveicula These are abnormal outpouchings or sacs of colon wall that occur due to interactions of high intraluminal pressures, disordered motility and low diet in fiber Formed on mesenteric side of antimesenteric taenia coli Results in protrusion of mucosa and submucosa through layers of muscle It is Pseudodiveiculum o...
Surgery
GIT
5e09e199-853c-45bb-a3ba-77983861b628
Receptor responsible for malignant hyperthermia is?
Nicotinic receptor
Ryanodine receptor
Muscarinic receptor
None
1b
multi
ANSWER: (B) Ryanodine receptorREF: Morgan 3ra e p. 869This condition is known by a number of names, including malignant hyperthermia (MH), malignant hyperthermia syndrome (MHS), and malignant hyperpyrexia.Signs and symptoms:The typical symptoms of malignant hyperthermia are due to a hyper catabolic state, which present...
Anaesthesia
Depolarising Neuromuscular Blocking Agents
b37bde23-8f8c-4286-b344-fde21a0ee1a9
Hinge axis face bow records:
Relationship of the mandible to the maxilla
Relationship of the mandible to the cranium
Relationship of teeth to the axis of the relation of the jaw
All of the above
2c
multi
Kinematic facebow or Hinge axis facebow A facebow with adjustable caliper ends used to locate the transverse horizontal axis of the mandible (GPT8) It locates the true (exact) centre of condylar rotation or transverse horizontal axis. It is preferred in full mouth reconstructions. Hinge axis face-bow records—relations...
Dental
null
b56c1677-06ff-4d74-be3c-8d0bf0aa99cc
During a routine checkup, a 50-year-old man is found to have blood in his urine. He is otherwise in excellent health. An abdominal CT scan reveals a 2-cm right renal mass. You inform the patient that staging of this tumor is key to selecting treatment and evaluating prognosis. Which of the following is the most importa...
Histologic grade of the tumor
Metastases to regional lymph nodes
Proliferative capacity of the tumor cells
Somatic mutations in the p53 tumor suppressor gene
1b
single
The choice of surgical approach or treatment modalities is influenced more by the stage of a cancer than by its cytologic grade. The significant criteria used for staging vary with different organs. Commonly used criteria include (1) tumor size, (2) extent of local growth, (3) presence of lymph node metastases, and (4)...
Pathology
Neoplasia
1e01454d-7a6c-4a71-b512-ea1430893e33
Part of colon with no mesentery-
Transverse colon
Sigmoid colon
Ascending colon
Rectum
2c
single
Ans. C. Ascending colona. The large intestine develops as a fully mesenteric organ. However, after the rotation of the gut tube in utero, large portions of it come to lie adherent to the retroperitoneum, which means that some parts of the colon are fixed within the retroperitoneum, and other parts are suspended by a me...
Anatomy
Large Intestine, Rectum, and Anal canal
3c2a012d-4eca-4eb9-b6cd-ac6318b6341f
Among patients with polymyositis, which one of the following auto-antibodies is associated with an increased risk of interstitial lung disease?
Anti-CCP antibody
Anti ds DNA antibody
Anti cardiolipin antibody
Anti-Jo-1 antibody
3d
single
Myositis Specific Antibodies Anti Jo-1 and anti synthetase antibodies Polymyositis and dermatomyositis with Interstitial lung disease, ahritis, mechanic's hands Anti-Mi-2 Dermatomyositis with rash Anti MDAS Dermatomyositis with rapidly progressive lung disease Anti-10 Juvenile dermatomyositis Anti-Signal recognition pa...
Medicine
Systemic Lupus Erythematous
b14abbfd-bb86-4729-ad6e-a16fa82d779b
One gm of Hb liberates _______ mg of billurubin .
40
34
15
55
1b
single
Approximately 35mg of bilirubin is formed from 1g of Hb. About 6g of Hb is broken down per day. A total of 300mg of bilirubin is formed everyday; of which 80% is from destruction of old RBCs, 10% from ineffective erythropoiesis and the rest 10% from degradation of myoglobin and other heme containing proteins. Reference...
Pediatrics
New born infants
f43dd649-4003-4a55-8023-18cad890d2cc
A 60-year-old man with no significant past medical history is scheduled for elective cholecystectomy. He has been taking aspirin daily. Preoperative recommendations should include which of the following?
Determination of prothrombin time (PT)
Estimation of platelet count
Discontinuation of aspirin 2 days before surgery
Discontinuation of aspirin at least 1 week before surgery
3d
single
Discontinuation of aspirin at least 1 week before surgery. Aspirin inactivates platelet cyclo-oxygenase and thus inhibits platelet aggregation. The effect of aspirin is irreversible and lasts for the entire life span of the platelets. Therefore, aspirin should be discontinued for at least 1 week before surgery.
Surgery
Miscellaneous
bc3c3aa6-96ee-477a-bea1-724ee0b906b1
Missing cases are detected by?
Active surveillance
Passive surveillance
Sentinel surveillance
Monitoring
2c
single
ANSWER: (C) Sentinel surveillanceREF: Park 20th edition page 38The word surveillance is the French word for "watching over"Sentinel surveillance is useful for answering specific epidemiologic questions because sentinel sites may not represent the general population or the general incidence of disease, they may have lim...
Social & Preventive Medicine
Concept of Control
7d193ac0-bb73-471b-bbb6-396fed67713f
Malignant transformation is commonly seen in:
Stomal ulcer
Gastric ulcer
Chronic duodenal ulcer
Postbulbar ulcer
1b
single
Ans. (b) Gastric ulcer* Malignant transformation is very rarely seen in gastric ulcer (<1%) - Not so common.* Giant gastric ulcer (>2cm) is associated with cancer in 6-15% cases* Of the above choices we can opt for choice B' only - but it is not so common.
Surgery
Stomach & Duodenum
6093968d-c9c6-4bb8-aad8-75bc7b681412
Eye lens dislocation seen in –a) Marfan\'s syndromeb) Homocystinuriac) Down\'s syndromed) Klinefelter syndrome
ac
a
ab
bc
2c
single
Marfan syndrome and homocystinuria can cause dislocation of lens.
Ophthalmology
null
a4d8b2ba-9d27-4da2-a762-83c272b10478
'First order 'symptoms of schizophrenias' schizopremia include all except:
Depersonilization
Running commentary of ones thoughts
Primary delusion
Somatic passivity
0a
multi
There are 11 first rank symptoms first three are related to thoughts - thought inseion , withdrawal & broadcasting next three are related to hallucinations -1St person ,2ND person & 3RD person next three are made phenomena remember MADE VOLITION, MADE IMPULSE, MADE AFFECT (mood) Last two are Somatic passivity & Delusio...
Surgery
null
3f396395-5c60-48c7-8404-c738c49cf46d
Micro nodular cirrhosis is commonly seen in all except,
Chronic hepatitis B
Alcoholic liver disease
Hemochromatosis
Chronic extra hepatic biliary obstruction
0a
multi
Ans. is 'a' i.e., Chronic hepatitis B Cirrhosis of the liver is a pathological entity which clinically represents the end stage of chronic liver disease.It is characterized by three features.Bridging fibrous septa Q in the form of delicate bands or broad scars linking portal tracts with one another and portal tracts wi...
Medicine
Cirrhosis and Alcoholic Liver Disease
fe6c28d2-8fef-4a90-a8d2-2b97370f156f
Most common cause of hypercalcemic crisis is :
Parathyroid adenoma
Parathyroid hyperplasia
Malignancy
Paget's disease
2c
single
A hypercalcaemiccrisisis an emergency situation with a severehypercalcaemia, generally above approximately 14 mg/dL (or 3.5 mmol/l)The most common cause is hypercalcemia of malignancy, although granulomatous diseases, previously undetected primary hyperparathyroidism, medication-induced hypercalcemia, and a few rarer c...
Surgery
Parathyroid and adrenal glands
58c3d6b9-d756-4140-ae3b-4731168ef147
Scarring loss of hair is seen in
Discoid lupus erythematosus
Atopic dermatitis
Alopecia areata
Systemic lupus erythematosus
0a
single
Conditions causing scarring alopecia Causes of non-cicatricial alopecia (non-scarring) Traumatic causes of scarring alopecia may be due to: Injury Surgery Radiation Traction (tight curls) Central centrifugal cicatricial alopecia Infections causing scarring alopecia include: Bacterial infection: boils and abscesses (Sta...
Dental
Autoimmune skin disorders
ad129b65-5e44-44d4-9495-8809bd9efa03
60 year old asymptomatic female shows following change in tunica media of blood vessels. Diagnosis?
Medial calcification
Medial fibrosis
Amyloidosis
None
0a
multi
Ans. (a) Medial calcificationMedial artery calcification (MAC) is also known as Monckeberg's arteriosclerosis, is a nonobstructive condition leading to reduced arterial compliance that is commonly considered as a nonsignificant finding.With the H&E stain, calcium appear deep blue-purple.
Pathology
Cellular Pathology
9285a130-99e1-4c2b-8e97-984eb4427877
The results of the pulmonary functions tests shown below, the best diagnosis is -ParametersActualPredictedFE VI (L)1[?]23[?]5-4[?]3FVC(L)4[?]14[?]6-5[?]4FEVL'FVC (%)2972-80PEF (L/min)80440-540DLCO120%100%
Asthma
Asbestosis
ARDS
Silicosis
0a
single
Ans. is 'a' i.e. Asthma o .All expiratory parameters are reduced in the data given with timed vital capacity of 29%.o FEV1/FVC is reduced in obstructive airway disease with lowering of peak expiratory flow rates. Due to air trapping in asthma the DLco may be normal or increased.
Medicine
Asthma