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135
e45b6ff9-fb5f-47fa-83a9-30e09d893967
A G2P1 A0 presents with full-term pregnancy with tranverse lie in the first stage of labour. On examination, cervix is 5 cm dilated, membranes are intact and fetal hea sounds are regular. What would be the appropriate management in this case :
Wait for spontaneous evolution and expulsion
External cephalic version
Cesarean section
All
2c
multi
Cesarean section
Gynaecology & Obstetrics
null
43fb2a4c-1d10-4c48-b2c8-c6b55911e3b6
Organic nitrates can lead to the development of tolerance when used chronically. Which of the following preparations is least likely to develop tolerance:
Sustained release oral nitroglycerine
Sublingual nitroglycerine
Transdermal nitroglycerine
Oral pentaerythritol tetranitrate
1b
multi
Tolerance develops to nitrates, when these are present constantly in the blood. Sublingual route leads to immediate action of nitrates and these act for a sho time. Other preparations mentioned in the question are more likely to give consistent plasma levels of nitrates leading to development of tolerance.
Pharmacology
CHF, Angina Pectoris and Myocardial Infarction
61d213ea-3ed8-487b-8ffa-35e6a5589ca7
Which of the following drugs is an inhibitor of cytochrome p450 enzymes?
Ketoconazole
Rifampicin
Phenytoin
Phenobarbitone
0a
single
Ans. (A) Ketoconazole(Ref: KDT 8th/e p30)Ketoconazole is a powerful microsomal enzyme inhibitor whereas rifampicin, phenobarbitone and phenytoin are enzyme inducers.
Pharmacology
General Pharmacology
ddc5513f-e167-44a3-b0f1-a9eb66bf1035
The mother of a 2-week-old infant reports that since birth, her infant sleeps most of the day; she has to awaken her every 4 hours to feed, and she will take only an ounce of formula at a time. She also is concerned that the infant has persistently hard, pellet-like stools. On your examination you find an infant with n...
Congenital hypothyroidism
Congenital megacolon (Hirschsprung disease)
Sepsis
Infantile botulism
0a
single
The clinical findings of congenital hypothyroidism are subtle, and may not be present at all at birth; this is thought to be a result of passage of some maternal T4 transplacentally. Infants with examination findings will usually have an umbilical hernia and a distended abdomen. The head may be large, and the fontanell...
Pediatrics
New Born Infants
680a03b7-e5bd-4f51-98de-a2c4bc9ea8b1
A 30 year old patient with radiographic appearance of endosteal bone formation, sclerosed bone is likely to be suffered from?
Garre's osteomyelitis
Chronic focaL sclerosing osteomyelitis
Acute osteomyelitis
Chronic osteomyelitis
1b
single
null
Pathology
null
f8fba79f-a606-4352-8fc1-95e46a7ae73f
Number of ovum at bih is
2-3 million
2-5 million
7-10 million
10-15 million
0a
single
In humans no ova formed after bih. at time of bih there are 2 million ova.Ref: Ganong&;s review of medical physiology; 24th edition; page no: 401
Physiology
Endocrinology
345ba827-103d-4ed8-a424-59ef76cfd596
All of the following is used for gradation of coma in Glasgow coma scale except-
Eye opening
Motor response
Verbal response
Bladder function
3d
multi
null
Medicine
null
9f44e46e-e779-4592-8329-2b54e2e9a7e5
A 40 year old male patient came for routine checkup. Patient is a smoker and has a sedentary lifestyle .General examination reveals truncal obesity. Physician warns the patient against the coronary heart disease chances. The physician is evaluating the risk factors which maybe all except:
High blood pressure
Gender
Obesity
Hard water drinking
3d
multi
Additional factors considered to play a part in coronary heart disease include high blood pressure, smoking, male gender, obesity (particularly abdominal obesity), lack of exercise, and drinking soft as opposed to hard water. Factors associated with elevation of plasma FFA followed by increased output of triacylglycero...
Biochemistry
null
e2924713-a49a-4bd2-8af6-764d38392141
A 30-year-old woman complains of weakness and fatigability over the past 6 months. She has a 3-month acute history of severe hypertension that has required treatment with antihypertensive medications. Radiographic examination reveals a tumor of her right suprarenal gland. The patient is diagnosed with a pheochromocytom...
Preganglionic sympathetic fibers
Postganglionic sympathetic fibers
Somatic motor fibers
Postganglionic parasympathetic fibers
0a
single
The preganglionic sympathetic fibers running to the adrenal gland would be cut during adrenalectomy for they synapse on catecholamine-secreting cells within the adrenal medulla. Unlike the normal route of sympathetic innervation, which is to first synapse in a sympathetic ganglion and then send postganglionic fibers to...
Anatomy
Abdomen & Pelvis
c1c24fde-a1db-404f-946f-ef5d33afd372
Treatment of choice for acute panic attacks is -
Barbiturates
Benzodiazepines
TCAs
MAO inhibitors
1b
single
Ans. is 'b' i.e. Benzodiazepines Treatment of Panic disorderso Two most effective treatment are:1) Pharmacotherapy:- The cornerstone of drug therapy is andidepressants. SSRIs (Fluoxetine or other) are the preferred agents. Because therapeutic effect of antidepressants takes some time to develop, intially Benzodiazepine...
Psychiatry
Panic Disorder
7204d483-9f5e-4617-8a8e-739d2c374b31
You are conducting an autopsy on a patient and you find the so-called ladder tears near the main lesion on a major blood vessel. What is the most likely cause of the injury and subsequent death of the person?
Rapid deceleration
Penetrating injury
Lightning strike
Strangulation
0a
multi
The aoa may rupture as a result of sudden deceleration as in A. The aoic rupture is circular and clean cut and appears as if it was cut by a sharp knife. Sometimes multiple transverse internal tears adjacent to the main rupture is seen and these are called ladder tears. Ref: Textbook of Forensic Medicine by Narayana Re...
Forensic Medicine
null
1d231372-d23e-4b29-ab7b-924b4d46812a
Dilution segment in nephron is:
Ascending LOH
Descending LOH
Collecting tubule
Proximal tubule
0a
single
Ans. a. Ascending LOH
Physiology
Kidneys and Body Fluids
42d3a313-0165-46b2-a7d1-6b93ef253ad6
Which of the following hormones exerts the least effect on calcium metabolism of bone tissue?
Androgen
Estrogen
Nor epinephrine
Thyroid hormone
2c
single
null
Physiology
null
9c8369fc-14e1-45f9-a3a5-25709a9cf714
A 9-year-old boy is brought with history of decreased urine output, cola colored urine and swelling of the face & hands of 2 days duration. He is hypeensive, has a puffy face and pitting edema of the lower limbs. He has history of skin lesions 4 weeks earlier. A diagnosis of post streptococcal glomerulonephritis is mad...
2 weeks
4 weeks
8 weeks
6 weeks
2c
single
C3 levels are likely to return to normal in- 8 weeks According to some sources, C3 level normalises in 6-8 weeks & according to other, its 8-12 weeks. So the closest ans- 8 weeks
Pediatrics
Nephritic & Nephrotic Syndrome
72c23fe1-1e2a-4b96-b0d5-2b8e2ff79dbc
A child has a history of profuse watery diarrhea, not taking orally and not passed urine for 2 days, which of the following to be given?
Milk
ORS
IV fluids
IV antibiotics
2c
multi
A child having a history of profuse watery diarrhea with poor oral intake and not passed urine for 2 days is suffering from diarrhea with dehydration and probably an acute renal failure of pre-renal types.Here the best choice is intravenous fluids.If IV access not possible, then you can give feed through Ryle's tube or...
Pediatrics
All India exam
f11aa600-629a-4bdc-a6cc-034e49da8753
The physical quality of life index takes into account all of the following factors except
Infant moality
Life expectancy at age one
Literacy
Income
3d
multi
Ref: Parks 23rd edition pg 17 PQLI includes literacy, infant moality rate and life expectancy at age 1.
Social & Preventive Medicine
Epidemiology
0a3f92ca-9afe-4e07-954f-b8587609e684
Prolactin secretion is inhibited by:
Dopamine antagonist
GABA
Neurophysin
Bromocripitine
3d
single
Ans. is 'd' i.e. BromocriptineRef. K.D.T. 4th/ep244, K.D.T 5th/ep217Prolactin is under predominant inhibitory control of hypothalamus through prolactin releasing inhibitory hormone (PRIH).PRIH is a dopamine that acts on pituitary lactotrope D2 receptor.So, Dopaminergic agonists decrease plasma prolactin levels. These a...
Pharmacology
Bromocriptine
eae3c974-9d82-4906-800b-f1d5d4534fa4
All are true about intermittent claudication except
Most common in calf muscle
Pain is positional
Atherosclerosis is impoant predisposing factor
relieved by rest
1b
multi
<p> Intermittent claudication: Crampy pain in the muscles seen in limbs. Due to aerial occlusion, metabolites like lactic acid and substance P accumulate in the muscle and cause pain. Site of pain depends on site of aerial occlusion. Most common site is calf muscles. Pain in foot is due to block in lower tibial and pla...
Surgery
Vascular surgery
d2b8926a-755b-4402-83f6-522f4578a0d3
Which of the following plays an important role in retinol mobilization?
Zinc
Iron
Manganese
Magnesium
0a
single
Zinc plays an important role in retinol mobilization.
Biochemistry
null
bb0188ae-5f1c-4c0a-a175-c57ab2a7f2f2
Following is true regarding opening snap :
It is a high-pitched diastolic sound
It s due to opening of stenosed aoic valve
It indicates pulmonary aerial hypeension
It preceedes the aoic component of second hea sound
0a
multi
Answer is A (It is a high pitched diastolic sound) Opening snap is brief high pitched sound heard in early diastole. Opening snap brief high pitched sound heard in early diastole (Ejection sound are heard in systole) It is usually due to stenosis of an (A.V.) most often mitral value. It follows second hea sound, A2 by ...
Medicine
null
76b3ef43-4f36-4b92-aca8-8b730d2a325c
A 20-year-old woman complains of headache and discomfort in both sides of her jaw. Physical examination reveals enlarged parotid glands that are slightly tender on palpation. There is reddening of the orifice of Stensen duct on intra oral examination; her temperature is 38.3degC, and the pulse rate is 80/min. Laborator...
single blood sample for a specific immunoglobulin G (IgG)
blood cell count
blood culture
single blood test for a specific immunoglobulin M (IgM)
3d
multi
A single test revealing a specific IgM antibody can confirm the disease. Acute and convalescent titers of specific IgG antibodies will also confirm the diagnosis of mumps. Urine, saliva, and throat swabs will grow the mumps virus, but blood does not. Salivary amylase is elevated but is relatively nonspecific. Of course...
Medicine
Infection
64658e9a-9034-42b1-99fe-aaad9cc2a587
Cell injury occurs due to
Decreased cellular ATP generation
Cytosolic Ca++
Membrane damage
Intracellular K+
0a
single
Cell injury occurs due to decreased generation of cellular ATP ATP is necessary for Na+--K+ ATPase pump and Ca pump action and many other cellular functions for the existence of the cell THE MORPHOLOGY OF CELL AND TISSUE INJURY It is useful to describe the structural alterations that occur in damaged cells before we di...
Pathology
General pathology
5f1231f2-b69e-4831-bc2c-768b79ff4b87
Hypotension with muffled heart sounds and congested neck veins is seen in?
Cardiac tamponade
Pericardial effusion
Constrictive pericarditis
Acute congestive heart failure
0a
single
Ans. A. Cardiac TamponadeBeck's triad is a collection of three medical signs associated with acute cardiac tamponade, an emergency condition wherein fluid accumulates around the heart and impairs its ability to pump blood. The signs are:1. Low arterial blood pressure2. Distended neck veins3. Distant, muffled heart soun...
Medicine
C.V.S.
9bd5d468-9668-41fb-a003-9c3eb987f81f
Sampson's Theory proposed to explain endometriosis is
Embolization of menstrual fragments through lymphatic channels.
Metaplastic changes in embryonal cell rests.
Reflux of menstrual endometrium.
Histogenesis by induction.
2c
single
Sampson's theory: Reflux of menstrual endometrium through fallopian tubes causes endometriosis.
Gynaecology & Obstetrics
null
a1197326-ba8b-4603-b934-ee5bafffe106
Russell's traction is used in:
Inter-trochanteric fracture
Fracture Shaft of femur
Low back ache
Flexion deformity of hip
0a
single
Russell's traction Trochanteric fractures (described as skin traction) Best treatment for interochanteric fracture is Dynamic hip screw. The fracture is reduced under X-ray control and fixed with Dynamic hip screw / Gamma nail or proximal femoral nail. Dynamic Hip Screw: OTHER OPTIONS: Fracture shaft femur- gallows tra...
Orthopaedics
Fracture Management
6906b562-bbbd-4800-bdbe-a010d9b6c096
Mucus plugs containing epithelial cell aggregations arranged as whorls of shed epithelium in the airway mucus plugs seen in bronchial asthma is known as:
CharcotLeyden crystals
Curshmann spirals
Creola bodies
None of above
1b
multi
(Refer: Robbins Pathologic Basis of Disease, 8thedition, pg no: 691) Histopathology of bronchial asthma The mucus plugs contain whorls of shed epithelium, spiral shaped mucus plugs called Curshmannspirals Numerous eosinophils. Charcot-Leyden crystals - collections of crystalloid made upof an eosinophil lysophospholipa...
Unknown
null
43dd09f7-80ed-484c-a4f4-2d4fafed564c
Simplest and most common method of measuring variation is
Mean
Median
SD
Range
3d
single
null
Dental
null
890f8311-b778-4ec6-886a-bcb5e4fe0193
If both the parents are carriers of the beta-thalassemia gene, the chance of having a child with thalassemia major in each pregnancy is
25%
50%
75%
100%
0a
multi
Normally, the majority of adult hemoglobin (HbA) is composed of four protein chains, two a and two b globin chains arranged into a heterotetramer. In thalassemia, patients have defects in either the a or b globin chain, causing production of abnormal red blood cells (In sickle-cell disease, the mutation is specific to ...
Pathology
General pathology
91662407-9e6a-49aa-9402-a166bdeb231b
Patients with chronic pancreatitis gives chain of lakes appearance in ERCP examination. Management is
Total pancreatectomy
Sphicteroplasty
Side to side pancteaticojejunostomy
Resecting the tail of pancreas and performing a pancteaticojejunostomy
2c
single
Surgical procedures in chronic pancreatitis Ideal procedure : DPPHR(Beger's procedure) In presence of poal vein thrombosis : Frey's Small duct disease : V- Shaped excision Disease recurrence in body and tail (after DPPHR, Whipple's or Longmire-Transverso procedure) : V-shaped drainage Disease limited to tail: Spleen - ...
Anatomy
G.I.T
aa2cb917-ab4d-44c6-a76a-dbf1baab0b17
Splaying and Cupping of the metaphysis is seen in –
Rickets
Scurvy
Paget's disease
Lead poisoning
0a
single
null
Pediatrics
null
362b3c4c-4a0a-4717-873b-1a8a0efb84f3
Hand foot mouth syndrome is caused by -
Parvovirus 6
Parvovirus 19
Coxsackie virus A 16
Coxsackie virus A 19
2c
single
HFMD id caused by coxsackie virus A16,A9,B1-3 REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.491
Microbiology
Virology
39895a7c-9d63-4e90-8bcf-824431ab28c5
Polyhydramnios-
2000cc
I500cc
l000cc
500cc
0a
single
Ans. is 'a' i.e., 2000cc
Gynaecology & Obstetrics
Hydramnios and Oligo Hydramnios
799b19e6-d582-4e37-b019-0c6884e41418
The WHO index for fluorosis is based on:
Dean's index
McKay's index
Community Fluorosis index
Public Health fluorosis index
0a
single
null
Dental
null
2ba0f9b4-2122-4660-be99-8feee2e7cf73
Choose the appropriate lettered structure in this magnetic resonance imaging (MRI) scan of the back. Cerebrospinal fluid (CSF) is produced by vascular choroid plexuses in the ventricles of the brain and accumulated in which space?
A
B
C
D
3d
single
(d) The cerebrospinal fluid (CSF) is found in the lumbar cistern, which is a subarachnoid space in the lumbar area. CSF is produced by vascular choroid plexuses in the ventricles of the brain, circulated in the subarachnoid space, and filtered into the venous system through the arachnoid villi and arachnoid granulation...
Anatomy
Upper Extremity
e8d2c1b9-5518-4f61-96b1-8d7858f0e9c9
Drug of choice for Mycoplasma pneumoniae is :
Penicillin
Tetracycline
Cefuroxime
Erythromycin
3d
single
Answer is D (Erythromycin):
Medicine
null
a92de0d0-7b3e-4f68-ad95-11fc9f1283ea
The treatment of acute Periapical abscess is
Endodontic therapy or extraction
Incision and drainage only
Pulp capping
None of the above
0a
multi
null
Dental
null
6321a0f9-9d63-41f9-b941-b92554e122b7
In myocardial infarction the infarct accquires hyperemic rim with an yellow centre at ?
3-7 days
10-20 days
7-14 days
1-2 hours
0a
single
Ans. is 'a' i.e., 3-7 days
Pathology
null
e7beecdc-9d6b-41a1-baf3-50f9690bea33
HbA2 is increased In -
Alfa-thalassemia
Iron deficiency anemia
Beta-thalassemia
Sickle cell trait
2c
single
<p>In beta thalassemia , hemoglobin electrophoresis shows presence of increased amounts of HbF,HbA2 and complete absence or presence of variable amounts of HbA.The increased level of HbA2 has not been found in any other hemoglobin abnormality except beta thalassemia .</p><p>Harsh mohan textbook of pathology 6th edition...
Medicine
Haematology
8ee459f4-736e-4552-b95a-a6453b34f58e
Gretaest psychiatric burden in society is due to?
Depression
Schizophrenia
OCD
Alcohol abuse
0a
single
ANSWER: (A) Depression.REF: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 8pt 8px; text-indent: 0; text-align: left">Psychiatric disorders contribute 33% of years lived with daily depression contributes to maximum burden followed by problems due to alcohol
Psychiatry
Major Depression
9520d222-6eab-4f18-ad41-e5e2e30b432d
A female infant is born approximately 10 weeks prematurely (at 30 weeks) and weighs 1710 gm. She has respiratory distress syndrome and is treated with endogenous surfactant. She is intubated endotracheally with mechanical ventilation immediately after bih. Over the first 4 days after bih the ventilator pressure and the...
Persistent foramen ovale
Patent ductus aeriosus
Ventricular septal defect
Pulmonary stenosis
1b
multi
Patent ductus aeriosus. The presence of a murmur could be indicative of any of the conditions. The presence of a continuous machine-like murmur is indicative of a patent ductus aeriosus (PDA). Usually, as in this case, the premature baby with PDA does not acutely become cyanotic and ill, although brief desaturations ca...
Surgery
null
8cce0360-9dad-40c0-b0e0-ea4b5235c653
Which of the following is the only intrinsic muscle of larynx that lies outside the laryngeal framework-
Cricothyroid
Superior constrictor
Cricopharyngeus
Lateral cricothyroid
0a
single
Cricothyroid is the only intrinsic muscle which lies outside the cartilagenous framework.
ENT
null
5e791046-4f23-47df-95f8-9fec52307ee3
Sarcoidosis is associated with:
Band keratopathy
Systemic amylodosis
Angioid streaks
Cataracta nigra
0a
single
Ans. (a) Band kerotopathySarcoidosis is associated the band keratopathy from metabolic derangement resulting in hypercalcemia and from chronic uveitis.
Ophthalmology
Cornea
1db27e6b-598b-47a2-b5b0-787bb34044c7
Which of the following is a direct branch of Inferior mesenteric artery?
Superior rectal artery
Middle rectal artery
Inferior rectal artery
Inferior epigastric artery
0a
single
Ans. A Superior rectal arteryRef: Gray's, 41st ed. pg. 1088, 1138Branches of Inferior Mesenteric Artery* Left colic artery: supplies descending colon* Sigmoid artery: supplies sigmoid colon* Superior rectal artery: terminal branch of IMA* Marginal branchesNote* Middle rectal artery: branch of internal iliac artery (ant...
Anatomy
Abdomen & Pelvis
57a76bc8-d79a-4e92-9a98-0fbc5dd20c89
Maternal moality is reduced to -
100
200
300
400
1b
single
In 2008,a global reduction in maternal death to 200 is estimated.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-515.
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
1d969ef2-9c72-4666-b8a0-61517135297e
Which of the following is a protease inhibitor ?
Lamivudine
Saquinavir
Delavirdine
Zidovudine
1b
single
null
Pharmacology
null
ddc0eb7b-cb17-40f5-83eb-491686df801a
How many pairs of spinal nerves are there?
30
32
31
34
2c
single
Ans. is 'c' i.e., 31 * There are 31 pairs of spinal nerves (8 cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal). Spinal nerves are mixed nerves containing both sensory and motor fibres.
Anatomy
Neuroanatomy
adbdfff0-31b6-4d82-b94b-eb2c7e6de49b
Blood supply of prelaminar optic nerve is
Short posterior ciliary arteries
Branch retinal artery
Ophthalmic artery
Meningeal arteries
0a
single
null
Ophthalmology
null
3a48db4a-e0c7-4521-960b-681b718b04f7
Which of the following group of drugs follows zero order kinetics with high dose
Phenytoin and Propranolol
Amiloride and probenacid
Alcohol and theophylline
Digoxin and propranolol
2c
single
drugs which follow zero order kinetics- methanol, ethanol mixed order - 1st order at a low dose and zero order at high dose- aspirin, phenytoin, tolbutamide, digoxin, warfarin, theophylline most of the drugs usually follow 1st order kinetics and they are considered safe drugs Ref: KD Tripathi 8th ed
Pharmacology
General pharmacology
6e0f954e-044b-45df-b84f-bbb9fb9c76cd
Fifth disease is caused by
Parvo virus 70
HPV
Hepatitis Virus
HPV
0a
single
(A) Parvo virus 70 # ERYTHEMA INFECTIOSUM (FIFTH DISEASE): The disease is caused by Human Parvovirus.> Erythema infectiosum is the most common clinical manifestation of human parvovirus infection.NAMENUMBERVIRUS(Rubeola) measles"First disease"Measles virusRubella, ("German Measles") identified in 1881."Third disease"Ru...
Microbiology
Misc.
170b8bb1-df6b-401c-94ae-2fd3f8b711a0
A patient of maniac depressive psychosis is on lithium, clozapine and fluphenazine. During the course of treatment, he developed seizures and tremors. He is drinking water heavily and had recurrent episodes of urination. Which drug is responsible for these complications: March 2012
Lithium
Clozapine
Fluphenazine
None of the above
0a
multi
Ans: A i.e. Lithium Drugs for Schizophrenia and side-effects Dose related side effects of lithium includes polyuria/polydypsia, weight gain, tremor etc. Common side effects of clozapine are anticholinergic, antiadrenergic etc. Potentially life threatening side effects includes fatal agranulocytosis, fatal myocarditis, ...
Psychiatry
null
cbb66e93-5341-46a2-bd8e-7f03ef765f8f
Thyroxine is synthesized from which amino acid
Arginine
Lysine
Methionine
Tyrosine
3d
single
The thyroid hormones, triiodothyronine (T3)and thyroxine (T4), are tyrosine-based hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism. Iodine is necessary for the production of T3 and T4. A deficiency of iodine leads to decreased production of T3 and T4, enlarges the thyro...
Physiology
Endocrinology
7e68e070-dab8-428d-8f30-fa73ad4c9293
The toxic effect of beta receptor antagonists includes all the following EXCEPT
Hypoglycemic episodes in diabetes
Worsening of preexisting asthma
Ischemic cardiac episode on abrupt discontinuation
Precipitate migrainic effect
3d
multi
null
Pharmacology
null
b0d2a048-02ed-4353-b8e0-b60ae9885e61
Which of the following is a differentiating feature of anopheles from aedes mosquito -
Pupa has broad siphon
Eggs are oval shaped
Wings unspotted
Popi are short
0a
single
Ans. is 'a' i.e., Pupa has broad siphon Differentiation between anopheiini and culiciniTribe GenusAnopheiini AnophelesCulicini Culex, Aedes, ManosniaEggs1. Laid singly2. Eggs are boat-shaped and provided with lateral floats1. Laid in duster or rafts, each raft containing 100 - 250 eggs (except-Aedes)2. Eggs are oval-sh...
Social & Preventive Medicine
Entomology
51b0fea6-592c-4967-b85b-a75862e5f80b
All of the following cause inhibition of CYP3A except.
Saquinavir
Ritonavir
Itraconazole
Erythromycin
0a
multi
Ans. (A) Saquinavir(Ref: Katzung 11th/e p58, 863)All the drugs given in the options are microsomal enzyme inhibitors. Among protease inhibitors, ritonavir is the strongest inhibitor of CYP3A4 enzymes whereas saquinavir is the weakest.
Pharmacology
Chemotherapy: General Principles
a6734dbc-2dff-4f24-a6ba-8d1d2ce4fdc0
Delinking Malaria activity from Family planning was under the recommendation of
Mudaliar committee
Chadah committee
Mukerji committee
Kaar Singh committee
1b
single
Chadah committee recommended that the vigilance operations in respect of the national malaria eradication programme should be the responsibility of the general health services ie primary health centres. Ref : Park 23rd edition Pgno : 874
Social & Preventive Medicine
Health programmes in India
842f97ac-d7fa-4a89-a9cc-780d7c0ed236
Hind milk is rich in?
Water
Fat
Proteins
Zinc
1b
single
Ans. b (Fat) (Ref. OP Ghai Essential Paediatrics 6th ed., 150)HIND MILK comes later towards the end of feed and richer in fat content and provides more energy, and satisfies the baby's hunger. Thus the composition of milk also varies during the phase of feeding. For optimum growth, the baby needs both fore and hind mil...
Pediatrics
Nutrition
5506684f-044a-4c7b-a6ee-380953bd12e9
Hunt Hess scale is used for
SAH
SDH
Menigiomas
Tuberculosis
0a
single
Ans. (a) SAH* Hunt and Hess Scale is used for Sub arachnoid hemorrhage* It helps to predict the outcome based on Clinical features.
Surgery
Nervous System
d12443e9-a2b8-4a57-b19b-e0e269d51767
Which is the medium used for Vibrio cholerae?
Thayer—Martin medium
TCBS medium
Scirrow’s medium
Loeffler’s medium
1b
single
null
Unknown
null
9d715d05-b8e4-4fda-bf8c-5c2a322da978
Myxoviruses include -a) Orthomyxovirusb) Influenzac) Measlesd) Polioe) HSV
ab
bc
acd
abc
3d
single
null
Microbiology
null
43466e5e-98d9-4558-9124-c5ed04c3a12d
Which nerve repair has the worst prognosis?
Ulnar
Radial
Median
Lateral popliteal
3d
single
Common peroneal nerve (Lateral popliteal nerve) has two main characteristics. The most common nerve lesions of the lower limb. Worst prognosis after nerve reconstructive surgery. Recovery potential after nerve repair Excellent: - Radial, Musculocutaneous, femoral, digital nerves Moderate: - Median, Ulnar, Tibial Poo...
Orthopaedics
null
e1e39568-2365-4b02-ac33-3ac4b91a847b
Macrocytic anemia may be seen in all of these except-
Liver disease
Copper deficiency
Thiamine deficiency
Vitamin B12 deficiency
1b
multi
Copper deficiency is manifested by hypochromic normocytic anemia, osteopenia, depigmentation, mental retardation and psychomotor abnormalities. Thiamine, pyridoxine and Bl2 deficiency leads to megaloblastic anemia. Classification of megaloblastic anemia
Pathology
null
06cd15f9-64eb-4adb-94c6-b356f2063b8c
The most important sign of significance of renal artery stenosis on an angiogram is –
A percentage diameter stenosis > 70%
Presence of collaterals
A systolic pressure gradient > 20 mm Hg across the lesion
Post–stenotic dilatation of the renal artery
1b
single
The presence of arterial collaterals indicates that renal artery stenosis is hemodynamically significant. The diameter of stenotic segment may also give an indication of hemodynamic significance, but is only reliable if the stenosis is either very severe or minimal .
Radiology
null
a8fae452-37bb-4d32-b9f6-4469e8951f6d
The epithelial lining of the urethra below the opening of the ejaculatory ducts is
Stratified cuboidal epithelium
Stratified columnar epithelium
Transitional epithelium
Stratified squamous epithelium
1b
single
The epithelium of the urethra stas off as transitional cells as it exits the bladder. Fuher along the urethra there are psuedostratified columnar and stified columnar epithelia, then stratified squamous cells near the external urethral orifice. There are small mucus-secreting urethral glands, that help protect the epit...
Anatomy
General anatomy
bd298c50-6fa6-45df-afea-6d85999e853a
A 37 year old primi Rh negative patient is very concerned above her pregnancy at this age. Her pregnancy is 16 weeks and she is HIV negative, hepatitis B surface Ag neg, Rubella non immune and has no complain.Her triple test report is normal but still due to her age she insists on getting an amniocentesis done.Which of...
Advise against amniocentesis as it will increase the risk of isoimmunisation
Follow Rh titres carefully and give Anti D if evidence of isoimmunisation is present
Give Anti D at 28 weeks of pregnancy and after delivery if baby is Rh neg
Give Anti D prior to her amniocentesis
3d
multi
Points worth noting are: Primi patient with Rh negative blood group She is 37 years old-elderly primi (>30 years) and has risk of Down syndrome (>35 years) She is concerned about the risk of having a down syndrome baby at this age and so insists on having amniocentesis done. Option a: Advise against amniocentesis as ...
Gynaecology & Obstetrics
null
686a1a53-d1f4-4465-a7e0-09dbac75c6f2
What is the pressure at which oxygen is stored?
75psi
1600psi
760 psi
2200 psi
3d
single
Ans. is 'd' i.e., 2200 psi GasType of cylinder and storage formColour codeCapacityPressurePin-IndexOxygenE. cylinderH. cylinder}GasBlack with white shoulderE-660 lit.H-6900 lit.2200 psi2.5Nitrous oxideEH}LiquidBlueE- 1590 lit.H-15800 lit.760 psi3.5AirE. gasGrey body with black & white shoulder625 lit.2000 psi1,5Carbond...
Anaesthesia
Breathing Systems
1b969fbf-b925-4aeb-8541-cb12031c2914
A 10 year old female patient complains of tiredness and shortness of breath. Patient is a known case of beta-thalassemia. This disease is caused by faulty splicing of:
hnRNA
snRNA
scRNA
snoRNA
0a
single
Faulty splicing can cause diseases: Splicing of hnRNA has to be performed with precision to produce functional mRNA. Faulty splicing may result in diseases. A good example is one type of beta-thalassemia in  humans. This is due to a mutation that results in a nucleotide change at an exon-intron junction. The result is ...
Biochemistry
null
173d0f3c-84a7-4c58-a298-41a1fde943ee
Heparin inhibits Xa by
Blocking vitamin K mediated activation of Xa
Activating Antithrombin III
Direct breakdown of Xa
Blocking P2 Y12 receptor of ADP
1b
single
Heparin contains pentasaccharide unit that activates Antithrombin III & inhibits factor Xa (Thus it is a indirect thrombin inhibitor). Unfractionised heparin also contains a heteropolysaccharide unit that inhibits factor II a. LMWH lacks this heteropolysacchoride unit and therefore inhibitors factor Xa only.
Pharmacology
null
63df7b09-e8fa-46f4-afdd-c6929d852b0e
TRUE about blood supply of scaphoid
Mainly through ulnar aery
Major supply from ventral surface
Major supply from dorsal surface
Proximal supply in antegrade fashion
2c
multi
Major blood supply to the scaphoid is the radial aery. 70-80 % of the intraosseous vascularity and the entire proximal pole is from branches of the radial aery entering through the dorsal ridge.
Anatomy
Upper limb : Miscellaneous
5785d8f2-5f50-424a-bbf2-c7997f0bfd9a
A girl 15 yrs of age is diagnosed with MRKH (Mayer Rokitansky kuster Hauser Syndrome). Which of these is true for her management?
Vaginoplasty to be done as soon as diagnosed
Sex of rearing should be male
Gonadectomy is to be performed
Child bearing can be possible through assisted reproduction
3d
multi
vaginoplasty should be done before onset of sexual activity sex of rearing should be female gonadectomy is to be done for Androgen Insensitivity Syndrome and not for MRKH as it has a normal functioning ovary child bearing is possible through assisted reproduction as the patient has normally functioning ovaries, through...
Gynaecology & Obstetrics
Intersex
b111b48d-3b49-420c-8738-8f60ac703f3c
The net protein utilization of rice is –
20%
40%
63%
81%
2c
single
null
Social & Preventive Medicine
null
43062ab0-4685-4f36-86d5-55f7c45a1025
For most effective cutting and long usefulness of a tungsten carbide bur, it should be
Rotating slowly before contacting the tooth
Rotating rapidly before contacting the tooth
Placed in contact with tooth before starting
Rotating rapidly before entering in to the oral cavity
1b
single
null
Dental
null
a1c85086-a8b0-419d-83f1-526650ce6507
Infective stage of hook worm is:
Trophozoite form
Filiform larva
Cyst
None
1b
multi
Ans. b. Filiform larva
Microbiology
null
246698aa-d624-49bb-af6c-b0140947423c
All of the following are examples of traction epiphysis, except -
Mastoid process
Tubercles of humerus
Trochanter of femur
Condyles of tibia
3d
multi
Condyles of tibia are pressure epiphysis. All other given options are traction epiphysis
Anatomy
null
55261ff4-9d94-4b4a-a34c-aa4bac475828
Stellate wound may be seen in which of the following bullet entry wounds -
Contact shot
Close shot
Distance shot
Two feet distance
0a
single
The synopsis of forensic medicine & toxicology ; Dr k.s narayan reddy ;28th edition ;pg.no 130 In a contact shot the muzzle blast & the negative pressure in the barrel following discharge may suck blood ,hair fragments, tissue,cloth fibers several cm. Back inside the barrel called back spatter .back spatter is more com...
Forensic Medicine
Mechanical injuries
d9d63f6c-138c-4e4f-8c9f-32049474f9dc
The level of blister formation in bullous pemphigoid is -
Intra epidermal
Sub epidermal
Subcorneal
None of the above
1b
multi
Ans. is 'b' i.e., Sub epidermal Site of blistersIntraepidermalSubepidermal (Dermo-epidermal)1) Subcorneal (granular layer)1) Junctional (at Basal lamina)o Blister is in granular layer or just below stratum corneumi) Junctional epidermolysis bullosaii) Bullous pemphigoidiii) Toxic epidermal necrolysi si) Pemphigus folia...
Skin
Pemphigoid Group
1da347e9-2770-47f1-a9d2-48c2d13eaa08
Koenen tumor seen in ?
Neurofibromatosis
Tuberous sclerosis
Struge weber syndrome
Tuberculosis
1b
single
Ans. is 'b' i.e., Tuberous sclerosis Periungual fibromas (Koenen's tumors) :? Present in 20% of patients of tuberous sclerosis. Develop in adult life. Small, pink, sausage-shaped growths arising from under the nail folds; may disto the nail plate.
Pathology
null
6bd6f414-a7e1-4f0e-a3fa-b8043b3656a1
All the following are causes of Transdative pleural effusion Except
Nephrotic syndrome
Rheumatoid ahritis
Myxedema
Constrictive pericarditis
1b
multi
TABLE 316-1 Differential Diagnoses of PleuralEffusions Transudative Pleural Effusions 1. Congestive hea failure 2. Cirrhosis 3. Nephrotic syndrome 4. Peritoneal dialysis 5. Superior vena cava obstruction 6. Myxedema 7. Urinothorax Ref Harrison 19th edition pg 1719
Anatomy
Respiratory system
913cb3d7-fd96-4f43-ba45-0eb572e579b9
Most common complication of cadwell-luc operation is:
oroantral fistula
Infraorbital nerve palsy
Hemorrhage
Orbital cellulitis
1b
single
Most common complication of Caldwell-Luc operation is injury to infraorbital nerve which occurs is 21% cases. Ref.Scott Brown 7/e,Vol 2,p1494.
ENT
Nose and paranasal sinuses
2b47a64c-cbdb-4b7b-8c1a-75387625936a
The basic tools of measurement in epidemiology are
Incidence, prevalence and index
Morbidity, mortality and disability
Rates, ratios and proportions
Endemic, pandemic and epidemic
2c
single
null
Dental
null
6beb2aef-93d4-4f71-b0a3-999d8c51ace5
Following is true about safety muscle of tongue
Innervated by cranial pa of accessory nerve
Hypoglossal nerve
Attached to hard palate
None of the given options
1b
multi
Ref BDC volume 3,6th edition pg 268Genioglossus is a life-saving muscle and its action is to protrude the tongueAll intrinsic and extrinsic muscles except palatoglossus are supplied by hypoglossal nerve
Anatomy
Head and neck
364d3b85-8af2-4444-a26f-2fc3f8a11d37
Most common sensorineural hearing loss in adults are due to
Meneries disease
Presbycusis
Meatal osteoarthritis
Osteosclerosis
1b
single
null
Medicine
null
65e500f1-1c49-47f7-9533-c1855dfe6e71
Hard palate contains:
Keratinized, submucosa, minor salivary gland
Keratinized, absent submucosal layer, minor salivary gland
Nonkeratinized, submucosal layer, minor salivary gland
Nonkeratinized, absent submucosa, minor salivary gland
0a
single
Ref. Gray’s anatomy.  41st edition. Page. 510 Hard Palate The hard palate is located on the roof of the oral cavity, posterior and medial to the alveolar process of the maxilla. The bony structure is formed by the palatine processes of the maxilla and the horizontal plates of the palatine bones. The periosteum is cove...
Unknown
null
675d328c-557f-494e-8a4e-9ab83d25a8a2
Which of the following components is a potent neutrophil chemotactic agent?
C 1
C 2
C5a
C789 complex
2c
single
C5a promotes chemotaxis. The complement components C l, C2, and the C789 complex do not promote chemotaxis.
Unknown
null
6806ad32-d165-420d-8db3-84bb152bf587
Which among the following can prevent coagulation of blood:
Calcium oxalate
Sodium citrate
Sodium iodide
Potassium chloride
1b
single
Ans b: (Ref: Guyton 11th edition p466-467)Methods to present blood coagulation in vitro1 Siliconized containers - Present contact activation of platelets & Factor 82 Heparin - Especially is heart lung machine /artificial kidney3 Oxalate compunds - By precipitation of calcium oxalate compounds4 Citrate compounds(Sodium ...
Pathology
Blood
67ce7c22-006f-49c5-a91a-f2a0aa6a4365
What is Neurapraxia: September 2010
Complete division of nerve
Loss of conduction due to axonal interruption
Irreversible injury
Reversible physiological nerve conduction block
3d
single
Ans. D: Reversible physiological nerve conduction block Neurapraxia is pa of Seddon's classification scheme used to classify nerve damage. It is a transient episode of motor paralysis with little or no sensory or autonomic dysfunction. Neurapraxia describes nerve damage in which there is no disruption of the nerve or i...
Surgery
null
8bd61490-9573-474d-a164-2c9c70977a3d
The pathogenicity of E. histolytica is indicated by:
Zymodeme pattern
Size
Nuclear pattern
ELISA test
0a
single
Ans. is 'a' i.e., Zymodeme patternZymodeme (isoenzyme) analysis: E. histolytica possesses several isoenzymes like malic enzyme, hexokinase, isomerase and phosphoglucomutase and these isoenzymes contribute in pathogenesis. When these isoenzymes are subjected to electrophoresis based on electrophoretic pattern (Zymodeme ...
Microbiology
Parasitology
61c6f088-881f-4451-91b8-5507939f7d9f
Increased incidence of breast carcinoma is seen with-
Sclerosing adenosis
Atypical hyperplasia
Apocrine metaplasia
Duct papilloma
1b
single
Ans. is 'b' i.e., Atypical hyperplasia o Patients with a history-' of breast biopsy for benign breast disease have an increased risk of breast cancer. The degree of increase in risk depends on the specific epithelial abnormality. The table below shows the relative associated risks for patients with benign histologic fi...
Surgery
Breast Cancer - Types and Staging
c958fd33-f95a-43ec-9d2e-51f04fa65765
Which type of pelvis is favorable for Face to pubis delivery?
Gynecoid
Android
Anthropoid
Platypelloid
2c
single
Ans. is 'c' i.e., Anthropoid Important educational points* Normal female pelvis - Gynaecoid pelvis* Male type pelvis - Android pelvis.* Most common type of pelvis - Gynaecoid pelvis.* Least common type pelvis - Platypelloid pelvis.* The only pelvis with AP diameter more than transverse diameter - Anthropoid pelvis.* Fa...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
6f2860f6-f9b9-446b-a36c-ce34dc265250
Rapid test used by WHO for tuberculosis ?
Quanteferon gold
ELISPOT
Xpe MTB
Sputum AFB
3d
single
Ans. is 'd' i.e., Sputum AFB Sputum smear microscopy is the quickest and easiest procedure. But it lacks both sensitivity and specificity. Smears are stained by ziehl-Neelsen acid-fast stain. Sputum smear examination (by AFB stain) is the method of choice for case finding. Note : Genexpe MTB/RIF is also a fast test (re...
Social & Preventive Medicine
null
cd3f15ff-2b89-4bdf-a51d-904abf731ebc
Ocular manifestations of dengue are all except
Cataract
Maculopathy
Vitreous hemorrhage
Optic neuropathy
0a
multi
Ans. (a) CataractRef: American Academy of Ophthalmology, BSCS, Section 9/p. 219* Dengue fever - caused by Flaviviridiae and transmitted by Aedes aegyptiOcular manifestations* Petechial subconjunctival hemorrhage - most common manifestation* Maculopathy (bilateral and asymmetric) - in 10% patients after one month of ons...
Ophthalmology
Retina
eef43146-af41-4e93-bf71-1192ac8f302c
Clomiphene citrate challenge test (CCCT) is used for
Assessing LH rise prior to ovulation
Used for accurate diagnosis of PCOS
Estimating the luteal phase defect
Method to asses the ovarian reserve of a woman
3d
multi
Clomiphene citrate challenge test : Used to asses the ovarian reserve of a woman On D3- Check serum FSH ON D5- D9 - Give 100mcg Clomiphene citrate (CC) On D10- Check serum FSH High FSH value on D3 which increases fuher on D10 : indicates poor reserve
Gynaecology & Obstetrics
Infeility (Eggs'plantation!)
a6458c48-90a3-4484-bbfa-bffa0a8140b3
Dryness of mouth with facial N.injury-site of lesion is at -
Chorda tympani N
Cerebellopontine angle
Geniculate ganglion
Concussion of tympanic membrane
0a
single
Chorda Tympani Nerve Carries
ENT
null
e4b531b2-5cc7-48a6-a0e4-eee21727a07e
Breast carcinoma is associated with all except:
BRCA1
BRCA2
TP53
ATR
3d
multi
ATR is associated with ataxia telengectasia.
Pathology
Breast
6235d1b3-c517-4e46-a68d-548302dfbba2
Results of a test were given as very satisfied, satisfied, dissatisfied, it representes
Nominal scale
Ordinal scale
interval scale
Ratio scale
1b
single
Scales can be: Qualitative: Categorical scales: Nominal : eg: names of countries . Dichotomous : eg: yes/no, presence/absence. Ordinal : severity of disease: mild/moderate/severe.eg: staging of cancer, kuppusamy socioeconomic class. Quantitative: Metric scales: Interval Ratio
Social & Preventive Medicine
Biostatistics
20242b8b-e7bd-4f6f-8ad6-a2caa840f676
Drug of choice for hepatitis B:
Beta interferon
Sofosbuvir
Simeprevir
Tenofovir
3d
single
Tenofovir is a first-line agent in the treatment of hepatitis B. It prevents the formation of 5' to 3' phosphodiester linkage essential for DNA chain elongation. Hence it causes premature termination of DNA transcription.
Medicine
Hepatitis
69237049-1faf-47a3-81f7-e47069db0abb
Gold standard for detection of gall stones is?
CECT
USG
XRAY
Cholecystography
1b
multi
Ans. is 'b' i.e., USG * Investigation of choice for cholelithiasis (gallstone in gallbladder) and choledocholithiasis (gallstone in common bile duct) is USG.Investigations of gall bladder diseases1) Ultrasonography: - This is the investigation of choice for the detection of gallstones, and obstructive jaundice. USG sho...
Radiology
G.I.T.
7b5cf9be-8170-480c-bdc8-97bcc3131f4d
All are components of gun-powder EXCEPT:
Charcoal
Lead peroxide
Potassium nitrate
Sulphur
1b
multi
Gun Powder is of two types: a) Black gun powder: Contains Potassium nitrate 75% + Charcoal 15% + sulphur 10% b) Smokeless Powder is of following types: -Single Base: Contains nitrocellulose -Double Base: contains nitrocellulose + nitroglycerine -Triple Base: Contains Nitrocellulose + Nitroglycerine + nitroguanidine
Forensic Medicine
Ballistics
fd0cb17d-e638-4d32-9fda-d07f70459a4f
A 45 day-old infant developed icterus and two days later symptoms and signs of acute liver failure appeared. Child was found to be positive for HbsAg. The mother was also HBs Ag carrier. The mother's hepatitis B serological profile is likely to be:
HBsAg positive only
HBsAg and HbeAg positivity
HBsAg and anti-HBe antibody positivity
Mother infected with mutant HB V
1b
single
HBeAg-positive women in third trimester frequently transmit infection to the fetus (80-90%) in the absence of immunoprophylaxis, whereas those who are negative rarely infect the fetus. Ref: Kliegman, Behrman, Jenson, Stanton (2008), Chapter 355, "Viral Hepatitis", In the book, "NELSON TEXTBOOK OF PEDIATRICS", Volume 2,...
Pediatrics
null
3f578c36-a457-4530-aa8f-e3ce6e8fb569
Objects are seen reduced in size in
Hypnagogic hallucinations
Lilliputian hallucinations
Psychomotor hallucinations
Haptic hallucinations
1b
multi
Lilliputian hallucinations (micropsia) objects are seen reduced in size. It is more properly regarded as an illusion Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 360
Anatomy
Special topics
e3f6f558-d281-4ba6-8d38-67e656922f8c
Which of the following is best associated with lumefantrine ?
Antirrtycobacterial
Antifungal
Antimalarial
Antiamoebic
2c
single
null
Pharmacology
null